MycoData

OncologyImmune supportCognition & nerves

Niu-Chang-Chih · 2023 · Research Article · Molecules (Basel, Switzerland)

Ergosterol Isolated from Antrodia camphorata Suppresses LPS-Induced Neuroinflammatory Responses in Microglia Cells and ICR Mice.

Inflammation caused by microglial activation is important in neurodegenerative diseases. In this research, we tried to identify safe and effective anti-neuroinflammatory agents by screening a natural compounds library and found that Ergosterol can inhibit the nuclear factor kappa-light-chain enhancer of the activated….

Immune supportEnergy & fatigueGut & microbiome

Reishi · 2023 · Journal Article · Phytomedicine: international journal of phytotherapy and phytopharmacology

Fermentation of Ganoderma lucidum and Raphani Semen with a probiotic mixture attenuates cyclophosphamide-induced immunosuppression through microbiota-dependent or -independent regulation of intestinal mucosal barrier and immune responses.

BACKGROUND: Probiotic fermentation is a promising strategy for improving the nutritional and functional properties of traditional Chinese medicines (TCMs). Ganoderma lucidum and Raphani Semen are famous TCMs that have been shown to help alleviate immune system disorders..

OncologyImmune supportMetabolic healthLiver support

Reishi · 2023 · Journal Article · Journal of primary health care

Ganoderma lucidum.

Metadata-grounded summary: This journal article indexes research on Ganoderma lucidum in Journal of primary health care in 2023. MycoData maps the paper to oncology, immune support, metabolic health, liver support based on its title, species context, article metadata, and study classification..

OncologyImmune supportEnergy & fatigueGut & microbiome

Maitake · 2023 · Preprint · journal metadata

Influence of Dried Maitake and Enoki Mushroom Addition on Antioxidant, Potentially Anti-inflammatory, and Anti-cancer Properties of Enriched Pasta

The influence of the addition of 2.5, 5, 7.5, and 10.0% of dried Enoki and Maitake mushrooms on the content of bioactive compounds and some pro-health properties of pasta was studied..

Shiitake · 2023 · Research Article · International journal of molecular sciences

Lentinula edodes Cultured Extract and Rouxiella badensis subsp. acadiensis (Canan SV-53) Intake Alleviates Immune Deregulation and Inflammation by Modulating Signaling Pathways and Epigenetic Mechanisms.

Puberty is a critical developmental period of life characterized by marked physiological changes, including changes in the immune system and gut microbiota development..

Immune supportMetabolic healthRespiratory

Cordyceps · 2023 · Preprint · journal metadata

Mechanism of alleviating acute lung injury in mice from serum metabolomics analysis of Cordyceps fumosorosea

Abstract Introduction Mechanism of alleviating acute lung injury in mice from serum metabolomics analysis of Cordyceps fumosorose a Aims This study investigated the potential anti-inflammatory effects of Cordyceps fumosorosea mycelia on lung health, with a focus on acute lung injury in mice..

Immune supportEnergy & fatigue

Oyster Mushroom · 2023 · Research Article · Foods (Basel, Switzerland)

Optimization of Plasma Activated Water Extraction of Pleurotus ostreatus Polysaccharides on Its Physiochemical and Biological Activity Using Response Surface Methodology.

This study focused on optimizing the extraction of P. ostreatus polysaccharides (POPs) using plasma-activated water (PAW).

Immune supportGut & microbiomeLiver supportRespiratory

Maitake · 2023 · Preprint · journal metadata

Pharmacokinetic Parameters and Tissular Biodistribution of 1,3 β-glucans From Maitake Pro4x in Balbc Mice.

The objective of this study was to examine the pharmacokinetic parameters of 1,3-beta-glucans from Maitake Pro4X in BALBc mice through oral and intravenous (IV) administration..

Zhu Ling · 2023 · Journal Article · International journal of biological macromolecules

Polyporus umbellatus polysaccharide iron-based nanocomposite for synergistic M1 polarization of TAMs and combinational anti-breast cancer therapy.

M1 polarization of tumor-associated macrophages (TAMs) is a promising approach to breaking through therapeutic barriers imposed by the immunosuppressive tumor microenvironment (TME)..

OncologyImmune supportMetabolic healthGut & microbiome

Maitake · 2023 · Journal Article · International journal of biological macromolecules

Preparation and structural characterization of acid-extracted polysaccharide from Grifola frondosa and antitumor activity on S180 tumor-bearing mice.

In this study, an acid-extracted polysaccharide (GFP-A) was extracted from the fruiting bodies of G. frondosa with 1 % hydrochloric acid solution.

OncologyImmune supportSkin & hydration

Chaga · 2023 · Preprint · journal metadata

Protective Effects of Lanostane Triterpenoids from Chaga Mushroom in Human Keratinocytes HaCaT Cell against Inflammatory and Oxidative Stresses

Inotodiol, a lanostane-type triterpenoid, and many phytochemicals from Chaga mushroom have been investigated for various allergic diseases. However, antiaging and anti-inflammatory activities of inotodiol under different types of oxidative stress and impact of inotodiol on collagen and hyaluronan synthesis are not….

Immune supportMetabolic health

Reishi · 2023 · Research Article · Journal of fungi (Basel, Switzerland)

Study on the Structure and Bioactivity of Ganoderma lucidum Polysaccharides under Cassava Stalk Stress.

Various carbon sources affect the growth of the G. lucidum fruiting body, and the cassava stalk is considered a promising carbon source for G.

Turkey Tail · 2022 · Journal Article · Lignin

4-Hydroxybenzoic Acid Secreted from Trametes versicolor Catalyzes the Oxidation of a Nonphenolic β-O-4 Lignin Model Dimer as Laccase Mediator

Metadata-grounded summary: This journal article indexes research on Trametes versicolor in Lignin in 2022. MycoData maps the paper to oncology, immune support based on its title, species context, article metadata, and study classification..

Maitake · 2022 · Journal Article · Mushroom Science and Biotechnology

Antioxidant activity of different parts of Grifola frondosa and fractionation of iron-binding proteins

Metadata-grounded summary: This journal article indexes research on Grifola frondosa in Mushroom Science and Biotechnology in 2022. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Shiitake · 2022 · Journal Article · Mushroom Science and Biotechnology

Biochemical characterization and application of glycoside hydrolases from Lentinula edodes

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in Mushroom Science and Biotechnology in 2022. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

Maitake · 2022 · Preprint · journal metadata

Cd3 Epsilon Immune Restorative Ability Induced by Maitake Pro4x in Immunosupressed Balbc Mice.

Abstract Objectives: The aim of this research was to determine if the rich beta glucan compound called Maitake Pro4X can recover the T cell/NK population depleted by Dexamethasone treatment in lymph nodes from cancer-free BALBc female mice..

Turkey Tail · 2022 · Journal Article · Mushroom Science and Biotechnology

Development of fermented tofu with mushroom koji from Trametes versicolor mycelium

Metadata-grounded summary: This journal article indexes research on Trametes versicolor in Mushroom Science and Biotechnology in 2022. MycoData maps the paper to oncology, immune support based on its title, species context, article metadata, and study classification..

Shiitake · 2022 · Journal Article · Abstracts of Papers Presented at the Meeting of the Mycological Society of Japan

Homologous recombination of PyrGin Lentinula edodes with transient CRISPR/Cas9 introduction

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in Abstracts of Papers Presented at the Meeting of the Mycological Society of Japan in 2022. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

OncologyImmune supportMetabolic healthLiver support

Reishi · 2022 · Journal Article · Mushroom Science and Biotechnology

Identification, characterization and expression of a glutamic protease gene from Ganoderma lucidum

Metadata-grounded summary: This journal article indexes research on Ganoderma lucidum in Mushroom Science and Biotechnology in 2022. MycoData maps the paper to oncology, immune support, metabolic health, liver support based on its title, species context, article metadata, and study classification..

OncologyImmune supportEnergy & fatigueRespiratory

Shiitake · 2022 · Research Article · Infection and drug resistance

In vitro Anti SARS-CoV-2 Activity and Docking Analysis of Pleurotus ostreatus, Lentinula edodes and Agaricus bisporus Edible Mushrooms.

BACKGROUND: Fungi are rich source of biologically active metabolites aimed for the improvement of human health through the prevention of various diseases, including infections and inflammatory disorders..

OncologyImmune supportMetabolic healthGut & microbiome

Wood Ear · 2022 · Journal Article · Trends in food science & technology

Insights into health-promoting effects of Jew's ear (Auricularia auricula-judae)

Jew's ear is an important cultivated edible mushroom. It contains high levels of melanin, carbohydrates, fiber, protein, amino acids, ergosterol, and ascorbic acids, and a very lower level of fat.

Shiitake · 2022 · Journal Article · Mushroom Science and Biotechnology

Marker-assisted selection of a novel Lentinula edodes cultivation strain with improved post-harvest quality

Immune supportMetabolic healthGut & microbiomeSkin & hydration

Snow Fungus · 2022 · Journal Article · Journal of food composition and analysis

Primary structure, physicochemical properties, and digestive properties of four sequentially extracted polysaccharides from Tremella fuciformis

Polysaccharides from Tremella spp. are known to have various functions and applications.

Immune supportMetabolic healthLiver support

Snow Fungus · 2022 · Research Article · Current issues in molecular biology

Tremella fuciformis Crude Polysaccharides Attenuates Steatosis and Suppresses Inflammation in Diet-Induced NAFLD Mice.

Nonalcoholic fatty liver disease (NAFLD) is a chronic liver disorder characterized by an enhanced accumulation of lipids, which affects around 40% of the world's population. The T..

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

Oyster Mushroom · 2021 · Journal Article · British poultry science

Agaricus subrufescens and Pleurotus ostreatus mushrooms as alternative additives to antibiotics in diets for broilers challenged with Eimeria spp.

1. The effect of A.

Wood Ear · 2021 · Journal Article · Mushroom Science and Biotechnology

Comparison of element content of dried mushrooms: Auricularia polytricha from Japan and China and Auricularia auricula-judae from China

Metadata-grounded summary: This journal article indexes research on Auricularia auricula-judae in Mushroom Science and Biotechnology in 2021. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

OncologyImmune supportMetabolic healthLiver support

Reishi · 2021 · Journal Article · Mushroom Science and Biotechnology

Cultivation of Ganoderma lucidum and G. sinense on medium containing bamboo chips

Metadata-grounded summary: This journal article indexes research on Ganoderma lucidum in Mushroom Science and Biotechnology in 2021. MycoData maps the paper to oncology, immune support, metabolic health, liver support based on its title, species context, article metadata, and study classification..

Shiitake · 2021 · Journal Article · Abstracts of Papers Presented at the Meeting of the Mycological Society of Japan

Genome sequencing of Lentinula edodes by Nanopore sequencing

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in Abstracts of Papers Presented at the Meeting of the Mycological Society of Japan in 2021. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

Shiitake · 2021 · Journal Article · Abstracts of Papers Presented at the Meeting of the Mycological Society of Japan

Identification of quantitative trait loci for high temperature development in Lentinula edodes fruitbodies by QTL-seq method

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in Abstracts of Papers Presented at the Meeting of the Mycological Society of Japan in 2021. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

Shiitake · 2021 · Journal Article · Journal of the Japanese Forest Society

Influence of A0-Layer Removal on Radiocesium Concentration and the Amount in Lentinula edodes Fruiting Body, Bed-log, and Soil in Forest

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in Journal of the Japanese Forest Society in 2021. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

Shiitake · 2021 · Journal Article · Japanese Journal of Mycology

Isolating sporulation-deficient (sporeless) mutant of Lentinula edodes and identifying single-nucleotide polymorphism linked to the mutant trait

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in Japanese Journal of Mycology in 2021. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

Immune supportCognition & nervesEnergy & fatigue

Lion's Mane · 2021 · Research Article · International journal of molecular sciences

Neuroprotective Metabolites of Hericium erinaceus Promote Neuro-Healthy Aging.

Frailty is a geriatric syndrome associated with both locomotor and cognitive decline, typically linked to chronic systemic inflammation, i.e., inflammaging. In the current study, we investigated the effect of a two-month oral supplementation with standardized extracts of H..

Shiitake · 2021 · Journal Article · Mushroom Science and Biotechnology

Purification and characterization of a novel GABA-synthesizing enzyme from Lentinula edodes

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in Mushroom Science and Biotechnology in 2021. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

Immune supportCognition & nervesGut & microbiome

Maitake · 2020 · Research Support, Non U.S. Gov'T · Journal of natural products

A (1→6)-Branched (1→4)-β-d-Glucan from Grifola frondosa Inhibits Lipopolysaccharide-Induced Cytokine Production in RAW264.7 Macrophages by Binding to TLR2 Rather than Dectin-1 or CR3 Receptors.

Mushroom polysaccharides including β-glucans possess various health-promoting properties and are known to be the major bioactive constituents of Grifola frondosa (GF), which is a popular edible and medicinal mushroom. Dectin-1, a pattern-recognition receptor, is responsible for recognizing β-glucans..

Immune supportSkin & hydration

Mesima · 2020 · Comparative Study · Medicine

A clinical pilot study to evaluate the efficacy of oral intake of phellinus linteus (sanghuang) extract on knee joint and articular cartilage: Study protocol clinical trial (SPIRIT Compliant).

BACKGROUND: Knee osteoarthritis (KOA) is the most common form of degenerative arthritis. We used Phellinus linteus (PL), which has been well-known anti-inflammatory function.

OncologyImmune supportCognition & nervesEnergy & fatigue

Niu-Chang-Chih · 2020 · Research Support, Non U.S. Gov'T · Brain and behavior

Antrodia camphorata polysaccharide resists 6-OHDA-induced dopaminergic neuronal damage by inhibiting ROS-NLRP3 activation.

INTRODUCTION: Parkinson's disease (PD) is a common degenerative disease of the central nervous system (CNS). The main pathological change is the apoptosis of dopaminergic neurons in the substantia nigra pars compacta (SNPc), thereby leading to dopamine reduction in nigral striatum..

Immune supportMetabolic health

Oyster Mushroom · 2020 · Research Support, Non U.S. Gov'T · Scientific reports

Glucose counteracts wood-dependent induction of lignocellulolytic enzyme secretion in monokaryon and dikaryon submerged cultures of the white-rot basidiomycete Pleurotus ostreatus.

The secretome complexity and lignocellulose degrading capacity of Pleurotus ostreatus monokaryons mkPC9 and mkPC15 and mated dikaryon dkN001 were studied in submerged liquid cultures containing wood, glucose, and wood plus glucose as carbon sources..

Turkey Tail · 2020 · Research Support, Non U.S. Gov'T · MicrobiologyOpen

Insights into the mechanism of cyanobacteria removal by the algicidal fungi Bjerkandera adusta and Trametes versicolor.

Fungal mycelia can eliminate almost all cocultured cyanobacterial cells within a short time. However, molecular mechanisms of algicidal fungi are poorly understood.

Immune supportMetabolic healthGut & microbiome

Mesima · 2020 · Research Support, Non U.S. Gov'T · FASEB journal: official publication of the Federation of American Societies for Experimental Biology

Phellinus linteus polysaccharide extract improves insulin resistance by regulating gut microbiota composition.

The hypoglycemic effect of Phellinus linteus polysaccharide extract (PLPE) has been documented in several previous studies, but the functional interactions among PLPE, gut microbiota, and the hypoglycemic effect remain unclear..

Snow Fungus · 2020 · Research Support, Non U.S. Gov'T · Journal of food biochemistry

Preparation, characterization, and cytokine-stimulating activity of oligosaccharides from Tremella fuciformis Berk.

The Tremella fuciformis Berk polysaccharides (TP) have significant cytokine-stimulating activity and low oral bioavailability owing to their large molecular volume..

OncologyImmune supportEnergy & fatigueMetabolic health

Maitake · 2020 · Research Support, Non U.S. Gov'T · Journal of food biochemistry

The hypoglycemic and renal protective effects of Grifola frondosa polysaccharides in early diabetic nephropathy.

Grifola frondosa is a basidiomycete polypore fungus. Polysaccharides from G.

Immune supportMetabolic health

Maitake · 2019 · Comparative Study · Food & function

A comparative study on the structures of Grifola frondosa polysaccharides obtained by different decolourization methods and their in vitro antioxidant activities.

Decolourization of polysaccharides is one of the crucial procedures that affects their structure, which is closely related to their bioactivity. Here, Grifola frondosa polysaccharide (GFP) was decolourized with H2O2 and AB-8 macroporous resin..

Immune supportRespiratory

Niu-Chang-Chih · 2018 · Research Support, Non U.S. Gov'T · Cytokine

Analogous corticosteroids, 9A and EK100, derived from solid-state-cultured mycelium of Antrodia camphorata inhibit proinflammatory cytokine expression in macrophages.

Antrodia camphorata mycelium is used in traditional Chinese medicine in Taiwan. The wild-type mycelium is rare and expensive, so a solid-state-cultured mycelium of A.

Shiitake · 2018 · Research Support, Non U.S. Gov'T · Fungal biology

Cell wall structure of secreted laccase-silenced strain in Lentinula edodes.

Laccase1 (Lcc1) is abundantly secreted from vegetative mycelia into culture medium by Lentinula edodes. Down-regulation of lcc1 in L.

Immune supportCognition & nervesMetabolic health

Almond Mushroom · 2018 · Research Support, Non U.S. Gov'T · Journal of food and drug analysis

Characteristics of fucose-containing polysaccharides from submerged fermentation of Agaricus blazei Murill.

Fucose is one of important residues of recognition pattern for many immune cells. In this study, we characterized bioactive fucose-containing acidic polysaccharides from submerged fermentation of Agaricus blazei Murill..

Immune supportMetabolic healthSkin & hydration

Lion's Mane · 2018 · Comparative Study · Nutrients

Chondroprotective Effects of a Standardized Extract (KBH-JP-040) from Kalopanax pictus, Hericium erinaceus, and Astragalus membranaceus in Experimentally Induced In Vitro and In Vivo Osteoarthritis Models.

The aim of this study was to investigate the chondroprotective effect of a standardized extract (KBH-JP-040) of the Korean traditional herbs Kalopanax pictus Castor-Aralia, Hericium erinaceus (Bull.) Persoon, and Astragalus membranaceus Schischkin on in vivo and in vitro osteoarthritis (OA) models..

Immune supportMetabolic healthGut & microbiome

Chaga · 2018 · Research Support, Non U.S. Gov'T · Food research international (Ottawa, Ont.)

Effects of simulated gastrointestinal digestion in vitro on the chemical properties, antioxidant activity, α-amylase and α-glucosidase inhibitory activity of polysaccharides from Inonotus obliquus.

This study was aimed to investigate the impacts of gastrointestinal digestion in vitro on the physicochemical properties and the biological activities of polysaccharides from Inonotus obliquus (UIOPS-1)..

Immune supportRespiratory

Chaga · 2018 · Research Support, Non U.S. Gov'T · Molecular and cellular probes

Immunopotentiating effect of Inonotus obliquus fermentation products administered at vaccination in chickens.

Vaccination is an important approach for the control of avian viral diseases. The aim of this study was to evaluate the immune-potentiating effect of oral administration of Inonotus obliquus fermentation products (IOFP) at vaccination in chickens..