MycoData

Metabolic changes of mushroom (Flammulina velutipes) applied with polyethylene (PE) material (Normal-PM) or nanocomposite reinforced PE packaging material (Nano-PM) were monitored using tandem mass tags (TMT) labeling combined with two-dimensional liquid chromatography-tandem mass spectrometry (2D LC-MS/MS) technique..

Energy & fatigueMetabolic health

High relevance

Yellow Morel · 2017 · Journal Article · International journal of biological macromolecules

Purification, antitumor and immunomodulatory activity of polysaccharides from soybean residue fermented with Morchella esculenta.

Crude polysaccharides (MPS) from soybean residue fermented with Morchella esculenta were extracted and purified by DEAE Sephadex A-50 chromatography and Sephadex G-100 size-exclusion chromatography in sequence. Three main fractions MP-1, MP-3 and MP-4 were obtained during the purification steps..

OncologyImmune supportLiver supportSkin & hydration

High relevance

Turkey Tail · 2017 · Journal Article · International journal of biological macromolecules

Quorum sensing molecule-farnesol increased the production and biological activities of extracellular polysaccharide from Trametes versicolor.

A novel strategy of exposing 2-day-old mycelia cultures to 0.8mM farnesol was developed to stimulate extracellular polysaccharide (EPS) production in Trametes versicolor submerged cultures..

OncologyImmune supportMetabolic health

High relevance

Shiitake · 2017 · Research Article · Food science & nutrition

Removal of cadmium from contaminated Lentinula edodes by optimized complexation and coagulation.

Heavy metal pollution is a serious problem for Lentinula edodes; however, the treatment of contaminated L. edodes has seldom been studied.

High relevance

Maitake · 2017 · Journal Article · Food chemistry

Rice bran polysaccharides and oligosaccharides modified by Grifola frondosa fermentation: Antioxidant activities and effects on the production of NO.

Rice bran polysaccharides (RBPSs) are valuable compounds with many biological activities. In this work, a fungus called Grifola frondosa, was selected to ferment defatted rice bran water extracts and modify the RBPSs, which were then isolated by ethanol precipitation and deproteinization..

Immune supportMetabolic health

High relevance

Lion's Mane · 2017 · Journal Article · International journal of biological macromolecules

Selenizing Hericium erinaceus polysaccharides induces dendritic cells maturation through MAPK and NF-κB signaling pathways.

In this study, polysaccharides extracted from Hericium erinaceus were modified to obtain its nine selenium derivatives, sHEP1-sHEP9. Their structures were identified, yields and selenium contents were determined, the phenotypic and functional maturation of murine bone marrow-derived dendritic cells (DCs) and relevant….

Immune support

High relevance

Turkey Tail · 2017 · Research Article · Bioprocess and biosystems engineering

Simultaneous production of laccase and degradation of bisphenol A with Trametes versicolor cultivated on agricultural wastes.

Solid state fermentation with Trametes versicolor was carried out on agricultural wastes containing bisphenol A (BPA). It was found that BPA degradation was along with the occurrence of laccase production, and wheat bran and corn straw were identified as suitable mixed substrates for laccase production..

Energy & fatigue

High relevance

Cordyceps · 2017 · Preprint · journal metadata

Stable Carbon Isotope Composition of the Lipids in Natural Cordyceps sinensis from Major Habitats in China and Its Substitutes

Cordyceps sinensis is one rare medicinal fungus produced in the Qinghai-Tibetan Plateau. Its quality and price varies hugely with different habitat, and its numerous substitutes have sprung up in functional food markets.

High relevance

Enoki · 2017 · Journal Article · International journal of medicinal mushrooms

Structural Characteristics of the Novel Polysaccharide FVPA1 from Winter Culinary-Medicinal Mushroom, Flammulina velutipes (Agaricomycetes), Capable of Enhancing Natural Killer Cell Activity against K562 Tumor Cells.

FVPA1, a novel polysaccharide, has been isolated from fruiting bodies of the culinary-medicinal mushroom Flammulina velutipes, a historically popular, widely cultivated and consumed functional food with an attractive taste, beneficial nutraceutical properties such as antitumor and immunomodulatory effects, and a….

OncologyImmune supportEnergy & fatigue

High relevance

Shiitake · 2017 · Research Article · Mitochondrial DNA. Part B, Resources

The complete mitochondrial genome of the widely cultivated edible fungus Lentinula edodes.

The complete mitochondrial genome of the widely cultivated edible fungus Lentinula edodes was determined using the next-generation sequencing technology. The circular molecule is 116,819 bp in length with a GC content of 30.75%..

Energy & fatigue

High relevance

Maitake · 2017 · Journal Article · Apoptosis: an international journal on programmed cell death

The induction of apoptosis and autophagy in human hepatoma SMMC-7721 cells by combined treatment with vitamin C and polysaccharides extracted from Grifola frondosa.

Polysaccharides extracted from the mushroom Grifola frondosa (GFP) are a potential anticancer agent. The objective of this study was to investigate the effect of GFP and vitamin C (VC) alone and in combination on the viability of human hepatocarcinoma SMMC-7721 and HepG2 cells..

OncologyImmune supportLiver support

High relevance

Turkey Tail · 2017 · Research Article · Journal of enzyme inhibition and medicinal chemistry

The lignicolous fungus Trametes versicolor (L.) Lloyd (1920): a promising natural source of antiradical and AChE inhibitory agents.

This study aimed to determine antiradical (DPPH• and •OH) and acetylcholinesterase (AChE) inhibitory activities along with chemical composition of autochtonous fungal species Trametes versicolor (Serbia). A total of 38 phenolic compounds with notable presence of phenolic acids were identified using HPLC/MS-MS..

Cognition & nerves

High relevance

Lion's Mane · 2017 · Journal Article · Journal of Asian natural products research

Three new isobenzofuranone derivatives from the fruiting bodies of Hericium erinaceus.

Three new isobenzofuranone derivatives erinaceolactones D-F (1-3), together with four known ones (4-7), were isolated from the fruiting bodies of Hericium erinaceus. Their structures were determined on the basis of comprehensive spectroscopic analyses including UV, 1D, 2D NMR and HR-TOF-MS..

High relevance

Mesima · 2017 · Journal Article · International journal of medicinal mushrooms

Tissue Inhibitor of Metalloproteinase-1 (TIMP-1) and IL-23 Induced by Polysaccharide of the Black Hoof Medicinal Mushroom, Phellinus linteus (Agaricomycetes).

Matrix metalloproteinase-9 (MMP-9) has diverse roles associated with cell growth, migration, invasion, and angiogenesis. Tissue inhibitor of metalloproteinase-1 (TIMP-1) is known to inhibit MMP-9 by complexing with it at a 1:1 ratio..

OncologyImmune supportLiver supportRespiratory

High relevance

Chaga · 2017 · Journal Article · Natural product communications

Triterpenes with Anti-invasive Activity from Sclerotia of Inonotus obliquus.

The methanolic extract [inhibition (%): 61.2±3.8 (p<0.01) at 100 μg/mL] and its EtOAc-soluble fraction [inhibition (%): 82.5±1.7 (p<0.01) at 100 μg/mL1 from the sclerotia of Inonotus obliquus collected in Japan significantly inhibited invasion of human fibrosarcoma HT1080 cells through matrigel-coated filters..

OncologyRespiratory

High relevance

Lion's Mane · 2017 · Journal Article · Journal of Asian natural products research

Two new isobenzofuranone derivatives from the fruiting bodies of Hericium erinaceus.

Two new isobenzofuranone derivatives erinaceolactones G and H (1 and 2) were isolated from the ethanolic extract of fruiting bodies of Hericium erinaceus. Their structures were characterized on the basis of spectroscopic evidences..

High relevance

Niu-Chang-Chih · 2017 · Research Article · Frontiers in microbiology

Vanillin Promotes the Germination of Antrodia camphorata Arthroconidia through PKA and MAPK Signaling Pathways.

Wild fruiting bodies of medicinal mushroom Antrodia camphorata are only found on the endemic species bull camphor tree, Cinnamomum kanehirae, in Taiwan. Despite the evident importance of the host components in promoting the growth of A.

High relevance

Zhu Ling · 2016 · Journal Article · Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

[Molecular cloning and characterization of two kind of heat-shock protein gene from Polyporus umbellatus].

With RT-PCR approaches, the full-length cDNA of two heat shock protein genes were cloned from total RNA of the Polyporus umbellatus sclerotium. The full open reading frame cDNA sequence of the Hsp90 was 2 091 bp, encoding 696 amino acid residues with a predicted molecular mass of 78.9 kDa..

Liver support

High relevance

Maitake · 2016 · Journal Article · Mikrobiologiia

[Role of the NO Synthase System in Response to Abiotic Stress Factors for Basidiomycetes Lentinula edodes and Grifola frondosa].

Effect of stressors (unfavorable pH and temperature or carbon and nitrogen limitation) on the synthesis of the components of the NO synthase signaling system was studied in submerged cultures of xylotrophic basidiomycetes Lentinula edodes and Grifola frondosa..

High relevance

Enoki · 2016 · Research Article · International journal of molecular sciences

A Jacalin-Related Lectin Regulated the Formation of Aerial Mycelium and Fruiting Body in Flammulina velutipes.

Flammulina velutipes, one of the most popular mushroom species in the world, has been recognized as a useful model system to study the biochemical and physiological aspects of the formation and elongation of fruit body. However, few reports have been published on the regulation of fruiting body formation in F..

High relevance

Shiitake · 2016 · Journal Article · International immunopharmacology

Activation of the NRF2-ARE signalling pathway by the Lentinula edodes polysaccharose LNT alleviates ROS-mediated cisplatin nephrotoxicity.

The nephrotoxicity of cisplatin (cis-DDP) limits its general clinical applications. Lentinan (LNT), a dextran extracted from the mushroom Lentinula edodes, has been shown to have multiple pharmacological activities..

OncologyImmune supportEnergy & fatigue

High relevance

Enoki · 2016 · Research Article · G3 (Bethesda, Md.)

Advances in Understanding Mating Type Gene Organization in the Mushroom-Forming Fungus Flammulina velutipes.

The initiation of sexual development in the important edible and medicinal mushroom Flammulina velutipes is controlled by special genes at two different, independent, mating type (MAT) loci: HD and PR. We expanded our understanding of the F..

High relevance

Almond Mushroom · 2016 · Journal Article · International journal of oncology

Agarol, an ergosterol derivative from Agaricus blazei, induces caspase-independent apoptosis in human cancer cells.

Agaricus blazei (A. blazei) is a mushroom with many biological effects and active ingredients.

OncologyEnergy & fatigue

High relevance

Shiitake · 2016 · Journal Article · Cancer immunology, immunotherapy: CII

Age-associated impairment of antitumor immunity in carcinoma-bearing mice and restoration by oral administration of Lentinula edodes mycelia extract.

Because cancer is associated with aging, immunological features in the aged should be considered in anticancer immunotherapy. In this study, we investigated antitumor immunity in aged mice using a CT26 colon carcinoma model..

OncologyImmune supportGut & microbiome

High relevance

Niu-Chang-Chih · 2016 · Research Article · Evidence-based complementary and alternative medicine: eCAM

Antcin K, a Triterpenoid Compound from Antrodia camphorata, Displays Antidiabetic and Antihyperlipidemic Effects via Glucose Transporter 4 and AMP-Activated Protein Kinase Phosphorylation in Muscles.

The purpose of this study was to screen firstly the potential effects of antcin K (AnK), the main constituent of the fruiting body of Antrodia camphorata, in vitro and further evaluate the activities and mechanisms in high-fat-diet- (HFD-) induced mice..

Energy & fatigueMetabolic healthLiver support

High relevance

Niu-Chang-Chih · 2016 · Journal Article · Antiviral therapy

Anti-herpes simplex virus activities of bioactive extracts from Antrodia camphorata mycelia.

BACKGROUND: Antrodia camphorata, a traditional Chinese medicine, is widely used in the treatment of liver diseases and cancers. Anti-inflammatory properties have also been described.

OncologyImmune supportLiver supportRespiratory

High relevance

Niu-Chang-Chih · 2016 · Research Article · Molecules (Basel, Switzerland)

Antiinflammatory and Antiphotodamaging Effects of Ergostatrien-3β-ol, Isolated from Antrodia camphorata, on Hairless Mouse Skin.

Ergostatrien-3β-ol (EK100), isolated from the submerged whole broth of Antrodia camphorata, has antidiabetic, hyperlipidemic, and hepatoprotective activities. However, the antiphotodamage activity of EK100 has still not been revealed..

Immune supportMetabolic healthLiver supportSkin & hydration

High relevance

Chaga · 2016 · Journal Article · International journal of biological macromolecules

Antioxidant activity of Inonotus obliquus polysaccharide and its amelioration for chronic pancreatitis in mice.

Inonotus obliquus polysaccharide (IOP) was extracted by water with a yield of 9.83% and purified by an anion-exchange DEAE cellulose column and Sephadex G-200 gel with a polysaccharide content of 98.6%..

Immune supportMetabolic health

High relevance

Maitake · 2016 · Journal Article · International journal of food science & technology

Antioxidant and antitumour activities of exopolysaccharide from liquid‐cultured Grifola frondosa by chemical modification

Grifola frondosa is a popular edible mushroom for its tasty flavour and can be used as a dietary supplement for its functional substances. In this study, an exopolysaccharide (EPS), purified from the submerged culture of G..

OncologyImmune supportEnergy & fatigue

High relevance

Enoki · 2016 · Journal Article · Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic]

Antitumor and Antioxidant Properties of Water-Soluble Polysaccharides from Submerged Mycelium of Flammulina velutipes.

The aim of the study was to evaluate antitumor and antioxidant properties of water-soluble polysaccharides from submerged myceliumn of Flammulina velutipes grown under optimized conditions..

OncologyImmune supportMetabolic health

High relevance

Niu-Chang-Chih · 2016 · Research Article · Frontiers in pharmacology

Antrodia camphorata Increases Insulin Secretion and Protects from Apoptosis in MIN6 Cells.

Antrodia camphorata is a Taiwanese-specific fungus which has been used clinically to treat hypertension, immune- and liver-related diseases and cancer; however, it has never been studied in type 2 diabetes mellitus (T2DM). Hyperglycemia in T2DM causes endoplasmic reticulum (ER) stress, leading to β-cell dysfunction..

OncologyImmune supportMetabolic healthLiver support

High relevance

Shiitake · 2016 · Research Article · SpringerPlus

Biosynthesis of Se-methyl-seleno-l-cysteine in Basidiomycetes fungus Lentinula edodes (Berk.) Pegler.

BACKGROUND: The aim of the current study was to investigate whether the Basidiomycetes fungus Lentinula edodes can biosynthesize Se-methyl-seleno-l-cysteine, a seleno-amino acid with strong anticancer activity, and to optimize the culture conditions for its biosynthesis..

Oncology

High relevance

Mesima · 2016 · Journal Article · International journal of medicinal mushrooms

Black Hoof Medicinal Mushroom Phellinus linteus (Agaricomycetes) Extracts Protect Against Radiation-Induced Hematopoietic Abnormality in Mice.

We investigated the effects of Phellinus linteus extracts (PLEs) against radiation damage in mice. First, BALB/c mice were irradiated once with γ-rays at 4, 5, 6, or 8 Gy and allowed to recover for 20 days..

Metabolic health

High relevance

Shiitake · 2016 · Research Article · Molecules (Basel, Switzerland)

Chemical Composition and Inhibitory Effect of Lentinula edodes Ethanolic Extract on Experimentally Induced Atopic Dermatitis in Vitro and in Vivo.

The ethanolic extract of Lentinula edodes was partially analyzed and then characterized for its efficacy in treating atopic dermatitis. Polyphenols were determined to be the major antioxidant component in the extract (6.12 mg/g), followed by flavonoids (1.76 mg/g), β-carotene (28.75 μg/g), and lycopene (5.25 μg/g)..

Immune supportSkin & hydration

High relevance

Chaga · 2016 · Journal Article · Journal of natural medicines

Chemical constituents from Inonotus obliquus and their antitumor activities.

Four new lanostane-type triterpenes (inonotusanes D-G, 1-4), including a 24,25,26,27-tetranorlanostane, together with 11 known compounds (5-15), including 7 lanostane derivatives, 2 steroids and 2 aromatic compounds, were isolated from the sclerotia of Inonotus obliquus..

Oncology

High relevance

Maitake · 2016 · Research Article · Experimental biology and medicine (Maywood, N.J.)

Cold-water extracts of Grifola frondosa and its purified active fraction inhibit hepatocellular carcinoma in vitro and in vivo.

Mushrooms are used in traditional Chinese medicine to treat a variety of diseases. Grifola frondosa (GF) is an edible mushroom indigenous to many Asian countries with a large fruiting body characterized by overlapping caps..

OncologyLiver support

High relevance

Shiitake · 2016 · Research Article · BioMed research international

Comparative Proteomic Analysis of Light-Induced Mycelial Brown Film Formation in Lentinula edodes.

Light-induced brown film (BF) formation by the vegetative mycelium of Lentinula edodes is important for ensuring the quantity and quality of this edible mushroom. Nevertheless, the molecular mechanism underlying this phenotype is still unclear..

Metabolic health

High relevance

Lion's Mane · 2016 · Research Article · Experimental and therapeutic medicine

Comparative studies on extracts from Hericium erinaceus by different polarity reagents to gain higher antioxidant activities.

Hericium erinaceus (H. erinaceus) is a source of exogenous antioxidants that has been traditionally used in China for the prevention and treatment of oxidative stress-associated disease.

High relevance

Maitake · 2016 · Journal Article · Applied biochemistry and biotechnology

Control of Grifola frondosa Morphology by Agitation and Aeration for Improving Mycelia and Exo-Polymer Production.

The present study describes the improved mycelia and exo-polymer production under control of Grifola frondosa morphology by changing the aeration rate and agitation intensity in a 25-L stirred fermentor..

Immune supportMetabolic health

High relevance

Turkey Tail · 2016 · Journal Article · Waste management & research: the journal of the International Solid Wastes and Public Cleansing Association, ISWA

Corn forage biological pretreatment by Trametes versicolor in a tray bioreactor.

Trametes versicolor is a white-rot fungus known to be efficient in lignin removal due to its complex extracellular lignocellulolytic enzymatic system. Therefore, it can be used in the treatment of lignocellulose waste from agro, food, and wood industries.

High relevance

Niu-Chang-Chih · 2016 · Research Article · International journal of molecular sciences

Dehydroeburicoic Acid from Antrodia camphorata Prevents the Diabetic and Dyslipidemic State via Modulation of Glucose Transporter 4, Peroxisome Proliferator-Activated Receptor α Expression and AMP-Activated Protein Kinase Phosphorylation in High-Fat-Fed Mice.

This study investigated the potential effects of dehydroeburicoic acid (TT), a triterpenoid compound from Antrodia camphorata, in vitro and examined the effects and mechanisms of TT on glucose and lipid homeostasis in high-fat-diet (HFD)-fed mice..

Energy & fatigueMetabolic healthLiver support

High relevance

Lion's Mane · 2016 · Journal Article · Applied biochemistry and biotechnology

Detoxification of Olive Mill Wastewater and Bioconversion of Olive Crop Residues into High-Value-Added Biomass by the Choice Edible Mushroom Hericium erinaceus.

Environmentally acceptable disposal of olive cultivation residues (e.g., olive prunings; olive pruning residues (OLPR)) and olive mill wastes is of paramount importance since they are generated in huge quantities within a short time..

High relevance

Enoki · 2016 · Journal Article · Carbohydrate polymers

Development, physiochemical characterization and forming mechanism of Flammulina velutipes polysaccharide-based edible films.

Edible films of Flammulina velutipes polysaccharide were prepared and characterized in terms of rheological, optical, morphologic, mechanical and barrier properties to evaluate their potential application in food packaging..

Immune supportEnergy & fatigue

High relevance

Shiitake · 2016 · Research Article · MicrobiologyOpen

Diversity and effect of Trichoderma spp. associated with green mold disease on Lentinula edodes in China.

Lentinula edodes, one of the most important edible mushrooms in China, is affected heavily by the infection of green mold that overgrows mushroom mycelia. We collected the diseased samples from main L.

High relevance

Almond Mushroom · 2016 · Research Article · PloS one

Effect of the Medicinal Agaricus blazei Murill-Based Mushroom Extract, AndoSanTM, on Symptoms, Fatigue and Quality of Life in Patients with Crohn's Disease in a Randomized Single-Blinded Placebo Controlled Study.

BACKGROUND: Ingestion of AndoSanTM, based on the mushroom Agaricus blazei Murill, has previously shown an anti-inflammatory effect through reduction of pro-inflammatory cytokines in healthy individuals and patients with Crohn's disease (CD)..

Immune supportEnergy & fatigue

High relevance

Mesima · 2016 · Journal Article · International journal of medicinal mushrooms

Effects of Black Hoof Medicinal Mushroom, Phellinus linteus (Agaricomycetes), Polysaccharide Extract in Streptozotocin-Induced Diabetic Rats.

In this article we report the healing effects of a Phellinus linteus fruiting body hot water extract (PLE) in streptozotocin (STZ)-induced diabetic rats. PLE was given before and after STZ..

Immune supportMetabolic health

High relevance

Chaga · 2016 · Journal Article · Molecular medicine reports

Effects of polysaccharides isolated from Inonotus obliquus against hydrogen peroxide-induced oxidative damage in RINm5F pancreatic β-cells.

The purpose of the present study was to elucidate the cytoprotective effects of polysaccharides isolated from Inonotus obliquus. The polysaccharides were extracted from the fruiting body of I.

OncologyImmune supportEnergy & fatigueMetabolic health

High relevance

Lion's Mane · 2016 · Journal Article · Bioresource technology

Efficient conversion of pretreated brewer's spent grain and wheat bran by submerged cultivation of Hericium erinaceus.

Brewer's spent grain (BSG) and wheat bran (WB) are industrial byproducts that accumulate in millions of tons per year and are typically applied as animal feed. Since both byproducts show a great potential as substrates for fermentation, the approach developed in this study consists of utilizing these lignocellulosic….

Cognition & nerves

High relevance

Turkey Tail · 2016 · Journal Article · Applied microbiology and biotechnology

Enhanced biodegradation of antibiotic combinations via the sequential treatment of the sludge resulting from pharmaceutical wastewater treatment using white-rot fungi Trametes versicolor and Bjerkandera adusta.

While anaerobic treatment is capable of treating pharmaceutical wastewater and removing antibiotics in liquid phases, solid phases may still contain significant amounts of antibiotics following this treatment..

High relevance

Turkey Tail · 2016 · Research Article · Molecules (Basel, Switzerland)

Enhancing the Antioxidant Ability of Trametes versicolor Polysaccharopeptides by an Enzymatic Hydrolysis Process.

Polysaccharopeptides (PSPs) are among the main bioactive constituents of Trametes versicolor (T. versicolor).

Immune supportEnergy & fatigue