MycoData

Cordyceps · 2018 · Research Article · Molecules (Basel, Switzerland)

Establishment of a PCR Assay for the Detection and Discrimination of Authentic Cordyceps and Adulterant Species in Food and Herbal Medicines.

Accurate detection and differentiation of adulterants in food ingredients and herbal medicines are crucial for the safety and basic quality control of these products..

OncologyLiver supportSkin & hydration

Chaga · 2018 · Journal Article · Nanoscale

Synthesis of porous Pd nanoparticles by therapeutic chaga extract for highly efficient tri-modal cancer treatment.

Porous palladium nanoparticles were designed and synthesized to maximize the pharmacological activity of the chaga mushroom (Inonotus obliquus) extract, which has anticancer and antibacterial activities..

Cordyceps · 2018 · Research Article · Proceedings of the National Academy of Sciences of the United States of America

The demise of caterpillar fungus in the Himalayan region due to climate change and overharvesting.

Demand for traditional medicine ingredients is causing species declines globally. Due to this trade, Himalayan caterpillar fungus (Ophiocordyceps sinensis) has become one of the world's most valuable biological commodities, providing a crucial source of income for hundreds of thousands of collectors..

Immune supportGut & microbiome

Chaga · 2018 · Journal Article · International immunopharmacology

The mast cell stabilizing activity of Chaga mushroom critical for its therapeutic effect on food allergy is derived from inotodiol.

While an anti-allergic effect of Chaga mushroom (Inonotus obliquus) has been indicated, its therapeutic effect on allergy and immunoregulatory mechanisms and chemical constituents directly responsible for that are hardly known..

Immune supportEnergy & fatigue

Oyster Mushroom · 2018 · Research Article · AMB Express

The use of fermented buckwheat to produce L-carnitine enriched oyster mushroom.

L-Carnitine is an essential compound that shuttles long chain fatty acids into mitochondria. The objective of this study was to produce L-carnitine enriched oyster mushroom (Pleurotus ostreatus) using common buckwheat fermented by Rhizopus oligosporus..

Shiitake · 2018 · Journal Article · Journal of food biochemistry

Valorization of spent shiitake substrate for recovery of antitumor fungal sterols by ultrasound‐assisted extraction

The ongoing expansion of mushroom industries has generated enormous spent mushroom substrate with the potential for production of valuable chemicals. This study aimed to investigate ultrasound‐assisted extraction (UAE) of fungal sterols from spent shiitake (Lentinula edodes) substrate (SSS) by response surface….

Oncology

OncologyImmune supportEnergy & fatigue

Cordyceps · 2017 · Research Article · PloS one

Isolation, Culture and Characterization of Hirsutella sinensis Mycelium from Caterpillar Fungus Fruiting Body.

The caterpillar fungus Ophiocordyceps sinensis (previously called Cordyceps sinensis) has been used for centuries in Asia as a tonic to improve health and longevity. Recent studies show that O..

Cordyceps · 2017 · Research Article · PloS one

Metabolomic profile and nucleoside composition of Cordyceps nidus sp. nov. (Cordycipitaceae): A new source of active compounds.

Cordyceps sensu lato is a genus of arthropod-pathogenic fungi, which have been used traditionally as medicinal in Asia. Within the genus, Ophiocordyceps sinensis is the most coveted and expensive species in China..

Metabolic health

Maitake · 2016 · Journal Article · International journal of medicinal mushrooms

Characterization of Cross-Flow Ultrafiltration Fractions from Maitake Medicinal Mushroom, Grifoia frondosa (Agaricomycetes), Reveals Distinct Cytotoxicity in Tumor Cells.

β-glucans from Basidiomycetes like Grifola frondosa (the maitake mushroom) are well known for their health benefits. Polysaccharide preparations from medicinal mushrooms such as G.

Shiitake · 2016 · Journal Article · Journal of microbiology and biotechnology

Identification and Characterization of Trichoderma Species Damaging Shiitake Mushroom Bed-Logs Infested by Camptomyia Pest.

The shiitake mushroom industry has suffered from Camptomyia (gall midges) pest, which feeds on the mycelium of shiitake mushroom during its cultivation. It has been postulated that fungal damage of shiitake bed-logs is associated with infestation by the insect pest, but this is not well understood..

Maitake · 2016 · Research Article · Cancer medicine

Maitake Pro4X has anti-cancer activity and prevents oncogenesis in BALBc mice.

The understanding of the molecular mechanisms of the immune tolerance induced by the tumoral microenvironment is fundamental to prevent cancer development or to treat cancer patients using immunotherapy. Actually, there are investigations about "addressed-drugs" against cancer cells without affecting normal cells..

OncologyImmune supportMetabolic health

Cordyceps · 2014 · Review Article · Journal of functional foods

Recent advances in Cordyceps sinensis polysaccharides: Mycelial fermentation, isolation, structure, and bioactivities: A review.

Cordyceps (Ophiocordyceps sinensis) sinensis, the Chinese caterpillar fungus, is a unique and precious medicinal fungus in traditional Chinese medicine which has been used as a prestigious tonic and therapeutic herb in China for centuries. Polysaccharides are bioactive constituents of C..

Cordyceps · 2026 · Review · Molecules (Basel, Switzerland)

Medicinal Mushrooms and Their Bioactive Compounds: From Traditional Use to Therapeutic Potential.

Medicinal mushrooms have become an important component of modern dietary supplementation and functional nutrition due to their diverse biological activities and long-standing use in traditional medicine..

Cognition & nervesLiver support

Almond Mushroom · 2026 · Randomized Controlled Trial · The American journal of psychiatry

Primary Prevention of PTSD Symptoms in Combat-Deploying Soldiers Using Attention Bias Modification: A Randomized Controlled Trial.

OBJECTIVE: Evidence suggests that attentional threat avoidance is associated with increased risk for posttraumatic stress disorder (PTSD). This study evaluated the efficacy of two attention bias modification (ABM) protocols designed to enhance attention toward threats as a primary prevention of PTSD..

Cognition & nervesLiver support

Almond Mushroom · 2026 · Randomized Controlled Trial · Alcohol (Fayetteville, N.Y.)

Your team is counting on you: Digital gamification and team motivation in alcohol aftercare.

BACKGROUND: Relapse after inpatient treatment for alcohol dependence is frequent, particularly within the first three months post-discharge. Cognitive Bias Modification (CBM), and specifically alcohol Approach Bias Modification (ABM), has demonstrated benefits in inpatient care, but its efficacy for aftercare remains….

Almond Mushroom · 2025 · Randomized Controlled Trial · Translational psychiatry

5-HTTLPR does not moderate the effect of attention bias modification for depression: a randomized sham-controlled trial.

The 5-HTTLPR polymorphism in the serotonin transporter gene SLC6A4 has previously been dubbed a plasticity marker. Within the 5-HTTLPR polymorphism, a SNP (rs25531) in the L-allele in the promoter region, affects the transcription efficacy of the SCL6A4, leading to functionally important differences related to….

Almond Mushroom · 2025 · Randomized Controlled Trial · Journal of anxiety disorders

A randomized clinical trial investigating the clinical impact of a game-based digital therapeutic for social anxiety disorder.

The objective of this study was to determine if a novel game-based digital therapeutic intervention reduced anxiety symptom severity in adults with clinically elevated symptoms of social anxiety disorder (SAD)..

Almond Mushroom · 2025 · Randomized Controlled Trial · Behaviour research and therapy

Active positive searching versus passive negative avoidance: A comparative investigation of large-scale offline attention bias modification training in nonclinical adolescents.

Attentional bias (AB), characterized by a disproportionate allocation of attention toward threat-related stimuli, constitutes a well-established cognitive mechanism underlying anxiety disorders..

Almond Mushroom · 2025 · Randomized Controlled Trial · Journal of behavior therapy and experimental psychiatry

Attend to the positive while feeling anxious: The effect of state anxiety on the effectiveness of Attentional Bias Modification.

BACKGROUND AND OBJECTIVES: Elevating state anxiety during Attentional Bias Modification (ABM) may improve its effectiveness by matching the emotional state experienced during the training with the emotional state under which it is intended that the learned pattern of attentional bias will subsequently operate..

Almond Mushroom · 2025 · Randomized Controlled Trial · The journal of pain

Attention and nocebo hyperalgesia: Testing a novel virtual reality attention bias modification paradigm.

Nocebo effects in pain (nocebo hyperalgesia) have received significant attention recently, with negative expectancies and anxiety proposed to be explanatory factors. While both expectancy and anxiety can bias attention, attention has been rarely explored as a potential mechanism involved in nocebo hyperalgesia..

Cognition & nervesEnergy & fatigueLiver support

Almond Mushroom · 2025 · Randomized Controlled Trial · Behavioural and cognitive psychotherapy

Combining internet-delivered cognitive behavioural therapy and attention bias modification for reducing depressive symptoms in firefighters: a randomized controlled trial.

BACKGROUND: Firefighters are frequently exposed to traumatic events and stressful environments and are at particularly high risk of depressive symptoms. AIMS: The present study aimed to examine the impact of a combined internet-delivered cognitive behavioral therapy (iCBT) and attention bias modification (ABM)….

Almond Mushroom · 2025 · Randomized Controlled Trial · Neuropsychopharmacology reports

Effectiveness of Attentional Bias Modification Combined With Cognitive Behavioral Therapy in Reducing Relapse Risk and Cravings in Male Patients With Alcohol Use Disorder: A Quasi-Randomized Controlled Trial.

BACKGROUND: Alcohol use disorder (AUD) is characterized by severe dependence on alcohol, poor impulse control, and heightened attention to alcohol-related cues. Attention bias modification (ABM) retrains individuals to distract attention from alcohol-related cues..

OncologyImmune supportEnergy & fatigueSkin & hydration

Cordyceps · 2025 · Review · Frontiers in nutrition

Effects of fungal supplementation on endurance, immune function, and hematological profiles in adult athletes: a systematic review and meta-analysis.

Edible fungi are rich in a wide array of bioactive compounds, and a growing body of evidence suggests that they possess anti-inflammatory, antioxidant, antitumor, anti-aging, and other beneficial properties..

Almond Mushroom · 2025 · Randomized Controlled Trial · Brain research

Prefrontal transcranial direct current stimulation enhances the analgesic effects of attention bias modification: a randomized controlled trial.

This study aimed to investigate whether high-definition transcranial direct current stimulation (HD-tDCS) augmented the effect of attentional bias modification (ABM) on pain perception and to explore the potential neuroimaging mechanism by functional infrared spectroscopy (fNIRS)..

OncologyImmune supportMetabolic healthLiver support

Niu-Chang-Chih · 2025 · Review · Naunyn-Schmiedeberg's archives of pharmacology

Unlocking the biological potential of methyl antcinate A: a new frontier in cancer and inflammation application.

Antrodia camphorata is a valued and scarce parasitic mushroom that exclusively proliferates on the inner cavity wall of the endangered tree Cinnamomum kanehirai Hay (Lauraceae), endemic to Taiwan..

Almond Mushroom · 2025 · Randomized Controlled Trial · Drug and alcohol review

What hepatology clinicians and their patients with alcohol-related liver disease think of wearable alcohol biosensors to aid abstinence from alcohol: A qualitative study.

INTRODUCTION: We aimed to determine acceptability and feasibility of innovative wearable alcohol biosensor monitors (ABM) for patients with alcohol-related liver disease (ALD) and their clinicians..

Liver support

OncologyImmune supportMetabolic healthLiver support

Reishi · 2024 · Review · Mycology

Bibliometric, taxonomic, and medicinal perspectives of Ganoderma neo-japonicum Imazeki: A mini review.

Ganoderma, a traditional medicine in Asian countries, has been used to prevent and treat various ailments for centuries. Ganoderma neo-japonicum (synonym Ganoderma bambusicola), also known as purple Lingzhi, is a species that is currently underutilised when compared to Ganoderma lucidum (Lingzhi)..

Shiitake · 2024 · Research Support, Non U.S. Gov'T · Viruses

Identification of a Novel Antiviral Lectin against SARS-CoV-2 Omicron Variant from Shiitake-Mushroom-Derived Vesicle-like Nanoparticles.

Lectins are a class of carbohydrate-binding proteins that may have antiviral activity by binding to the glycans on the virion surface to interfere with viral entry..

Respiratory

Almond Mushroom · 2024 · Randomized Controlled Trial · Journal of behavior therapy and experimental psychiatry

Inhibition moderates the effect of attentional bias modification for reducing residual depressive symptoms: A randomized sham-controlled clinical trial.

OBJECTIVES: Residual symptoms represent risk factor for relapse. Attention bias modification (ABM) may reduce clinical and sub-clinical depressive symptoms, indicating that is may be of relevance when preventing relapse..

Cognition & nervesEnergy & fatigue

Almond Mushroom · 2024 · Randomized Controlled Trial · European archives of psychiatry and clinical neuroscience

Neural mechanisms underlying attentional bias modification in fibromyalgia patients: a double-blind ERP study.

There is a growing interest in the potential benefits of attentional bias modification (ABM) training in chronic pain patients. However, studies examining the effectiveness of ABM programs in fibromyalgia patients have demonstrated inconclusive effects on both behavioral indices and clinical symptoms..

Almond Mushroom · 2024 · Randomized Controlled Trial · Journal of behavior therapy and experimental psychiatry

Testing a brief attention training protocol to prevent emotional distress from a fear induction procedure.

BACKGROUND AND OBJECTIVES: Attentional hypervigilance to threat in posttraumatic stress disorder (PTSD) is an important topic to investigate. Efforts to leverage attention training to prevent PTSD have been promising but underlying mechanisms have not been fully elucidated..

Almond Mushroom · 2024 · Randomized Controlled Trial · Scientific reports

The effect of attentional bias modification on positive affect dynamics.

Negative attentional bias and alterations in positive affect dynamics constitute emotional vulnerability to depression. Attentional bias modification (ABM) aims to reduce emotional vulnerability to depression by fostering attentional deployment towards positive stimuli..

Cordyceps · 2023 · Journal Article · Canadian journal of microbiology

Detection of the pathogenic fungus Cordyceps farinosa in the Thitarodes armoricanus soil-rearing environment based on nucleic acid targets.

Cordyceps farinosa, an entomopathogenic fungus, infects and leads to high mortality of Thitarodes armoricanus larvae, which die soon after the infection of C. farinose, usually before the colonization of Ophiocordyceps sinensis owing to competitive inhibition and fruiting body formation.

Maitake · 2023 · Journal Article · Life sciences

Maitake α-glucan promotes differentiation of monocytic myeloid-derived suppressor cells into M1 macrophages.

AIMS: Myeloid-derived suppressor cells (MDSCs) are major components of the tumor microenvironment and systemically accumulate in tumor-bearing hosts and patients with cancer, facilitating cancer progression..

Oyster Mushroom · 2023 · Journal Article · World J Microbiol Biotechnol

Nutrient uptake in supplemented substrate by oyster mushroom

Spent mushroom substrate (SMS) is a promising alternative for supplementing oyster mushroom substrate, replacing conventional cereal bran. Therefore, the objective was to evaluate the production of Pleurotus ostreatus supplemented with Lentinula edodes' SMS, through the nutritional analysis of the substrate..

Oyster Mushroom · 2023 · Journal Article · World journal of microbiology & biotechnology

Nutrient uptake in supplemented substrate by oyster mushroom.

Energy & fatigueRespiratory

Oyster Mushroom · 2023 · Research Article · International journal of molecular sciences

Oyster Mushroom Spherical Virus Crosses the Species Barrier and Is Pathogenic to a New Host Pleurotus pulmonarius.

Oyster mushroom spherical virus (OMSV) is a mycovirus with a positive-sense single-stranded RNA genome that infects the edible mushroom Pleurotus ostreatus. OMSV is horizontally transferred from an infected strain to a cured strain via mycelia..

Cordyceps · 2023 · Journal Article · International journal of medicinal mushrooms

Polysaccharide Elicitors Affect the Yield, Polysaccharide Synthase and Antibacterial Activity of Intracellular Polysaccharides from Submerged Culture of Cordyceps milifaris (Ascomycetes).

This study aimed to increase the yield of Cordyceps militaris intracellular polysaccharide (IPS) by adding elicitors. By comparing the effects of different elicitors on the IPS yield, three polysaccharide elicitors with significant promoting effect were screened out: Tween 80, pH, and vitamin B6 (VB6)..

Immune support

Energy & fatigueGut & microbiomeSkin & hydration

Shiitake · 2022 · Journal Article · Bioscience, biotechnology, and biochemistry

A new method for the preparation of a purified glucosylceramide and ceramide from shiitake mushroom.

Ingestion of plant and fungal glucosylceramides is known to reduce colon carcinogenesis and skin barrier damage in mice and humans. However, such effects in animal experiments have not been revealed for plant and fungal ceramides because the content of ceramides contained in plants and fungi is so low that the large….

Cordyceps · 2022 · Journal Article · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Adenosine derivatives from Cordyceps exert antitumor effects against ovarian cancer cells through ENT1-mediated transport, induction of AMPK signaling, and consequent autophagic cell death.

Cordyceps militaris is rich in adenosine derivatives, including 3'-deoxyadenosine, also known as cordycepin. It has been reported for antitumor effects, but its underlying molecular mechanism has yet to be elucidated..

Oncology

Reishi · 2022 · Research Article · Molecules (Basel, Switzerland)

Assessment of Cosmetic Properties and Safety of Use of Model Washing Gels with Reishi, Maitake and Lion's Mane Extracts.

Natural cosmetics are becoming more and more popular every day. For this reason, this work investigates the properties of mushroom extracts, which are not as widely used in the cosmetics industry as plant ingredients..

Skin & hydration

Oyster Mushroom · 2022 · Research Article · Foods (Basel, Switzerland)

Bioactive Metabolites from the Fruiting Body and Mycelia of Newly-Isolated Oyster Mushroom and Their Effect on Smooth Muscle Contractile Activity.

Higher basidiomycetes are recognized as functional foods due to their bioactive compound content, which exerts various beneficial effects on human health, and which have been used as sources for the development of natural medicines and nutraceuticals for centuries..

Energy & fatigue

Shiitake · 2022 · Journal Article · Bioresource technology

Shiitake cultivation as biological preprocessing of lignocellulosic feedstocks - Substrate changes in crystallinity, syringyl/guaiacyl lignin and degradation-derived by-products.

Formulation of substrates based on three hardwood species combined with modulation of nitrogen content by whey addition (0-2%) was investigated in an experiment designed in D-optimal model for their effects on biological preproceesing of lignocellulosic feedstock by shiitake mushroom (Lentinula edodes) cultivation..

Cordyceps · 2021 · Journal Article · Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

[Comparison of endogenetic microbial community diversity between wild Cordyceps sinensis,artificial C. sinensis and habitat soil].

To obtain the difference of the fungal and bacterial community diversity between wild Cordyceps sinensis, artificial C. sinensis and their habitat soil, Illmina Hiseq high-throughput sequencing technology was applied.

Oyster Mushroom · 2021 · Research Article · Foods (Basel, Switzerland)

Accumulation of Selected Metal Elements in Fruiting Bodies of Oyster Mushroom.

The species Pleurotus ostreatus is a commercially, gastronomically, and biotechnologically important fungus. Its strain variability has been little researched.

Reishi · 2020 · Review · Applied microbiology and biotechnology

Mushroom extracts and compounds with suppressive action on breast cancer: evidence from studies using cultured cancer cells, tumor-bearing animals, and clinical trials.

This article reviews mushrooms with anti-breast cancer activity. The mushrooms covered which are better known include the following: button mushroom Agaricus bisporus, Brazilian mushroom Agaricus blazei, Amauroderma rugosum, stout camphor fungus Antrodia camphorata, Jew's ear (black) fungus or black wood ear fungus….

Oncology

OncologyImmune supportEnergy & fatigueMetabolic health

Cordyceps · 2019 · Review Article · Molecules (Basel, Switzerland)

Therapeutic Potential and Biological Applications of Cordycepin and Metabolic Mechanisms in Cordycepin-Producing Fungi.

Cordycepin(3'-deoxyadenosine), a cytotoxic nucleoside analogue found in Cordyceps militaris, has attracted much attention due to its therapeutic potential and biological value. Cordycepin interacts with multiple medicinal targets associated with cancer, tumor, inflammation, oxidant, polyadenylation of mRNA, etc..

Enoki · 2015 · Case Reports · Arerugi = [Allergy]

[A case of anaphylaxis caused by enokitake (Flammulina velutipes) ingestion].

Enokitake (Flammulina velutipes, winter mushroom) is a common edible mushroom in Japan. We experienced a case of anaphylaxis after enokitake ingestion.

Skin & hydration