MycoData

Reishi · 2023 · Preprint · journal metadata

Effect of dissolved oxygen regulation on the content of ganoderic acid S and R in mycelium of Ganoderma lucidum in a two-stage culture by oscillatory-stationary culture

Currently, liquid fermentation is regarded as a feasible method for cultivating thyme as contrast to subentity culture. Nevertheless, the production of ganoderic acid S and R is still rather limited, thus requiring the need for parameter adjustment in the liquid fermentation process..

Immune supportEnergy & fatigueMetabolic healthSkin & hydration

Chaga · 2023 · Preprint · journal metadata

Protective effect of Inonotus obliquus polysaccharide on fibroblasts after MGO-induced nonenzymatic glycation

Abstract Background Nonenzymatic glycation of fibroblasts causes functional downregulation and behavioral disorders in skin. Methods To investigate the effect of Inonotus obliquus on the nonenzymatic glycation of skin, we examined advanced glycation end product (AGE) inhibition by four extract fractions: n-butanol,….

Enoki · 2023 · Preprint · journal metadata

The genome sequence of the Velvet Shank, Flammulina velutipes (Curtis) Singer, 1951

We present a genome assembly from a specimen of Flammulina velutipes (the Velvet Shank; Basidiomycota; Agaricomycetes; Agaricales; Physalacriaceae). The genome sequence is 37.4 megabases in span.

Shiitake · 2021 · Preprint · journal metadata

Corncob as a Substrate for the Cultivation of Lentinula Edodes

Abstract Corncob is a major agricultural waste in the world. The study aims to evaluate the effect of using corncob as a substrate for Lentinula edodes cultivation, so as to provide an economic and eco-friendly approach to transform waste biomass into high quality edible mushrooms (whose original substrate - wood - is….

Oyster Mushroom · 2021 · Preprint · journal metadata

Development of Mycelium Materials Incubating Pleurotus Ostreatus Fungi With Different Substrates Composed of Poplar Sawdust and Cottonseed Hull

The mycelium materials incubating Pleurotus ostreatus fungi based on different substrate compositions were developed, the main components of which were poplar sawdust and cottonseed hull in different proportions..

OncologyImmune supportEnergy & fatigue

Shiitake · 2021 · Preprint · journal metadata

Selenium-Containing Exopolysaccharides Isolated from the Culture Medium of Lentinula edodes: Structure and Biological Activity

In continuation of our research on the influence of selenium incorporation on the biosynthesis, structure, immunomodulatory and antioxidant activities of polysaccharides of fungal origin, we have isolated from a post-culture medium of Lentinula edodes a selenium (Se)-containing exopolysaccharide fraction composed….

Energy & fatigueMetabolic healthGut & microbiome

Oyster Mushroom · 2021 · Preprint · journal metadata

Treatment of Rice Stubble with Pleurotus Ostreatus and Urea Improves the Growth Performance in Slow-Growing Goats

The objective of this study was to evaluate the efficacy of fungal treatment (Pleurotus ostreatus) of urea-treated rice stubble on growth performance in slow-growing goats..

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

Cordyceps · 2020 · Journal Article · Natural product research

1H NMR-based metabonomics of the hypoglycemic effect of polysaccharides from Cordyceps militaris on streptozotocin-induced diabetes in mice.

The crude polysaccharide was extracted from Cordyceps militaris. Material ratio of powder and water was 1:10.

OncologyImmune supportEnergy & fatigueRespiratory

Cordyceps · 2020 · Research Article · Mycobiology

Beneficial Effect of Cordyceps militaris on Exercise Performance via Promoting Cellular Energy Production.

Cordyceps militaris has been reported to the diverse pharmaceutical effects including cancer, inflammatory diseases, and bacteria or virus infection. However, the effect of C.

Immune supportEnergy & fatigueMetabolic healthLiver support

Reishi · 2020 · Journal Article · International journal of medicinal mushrooms

Bioactivities and Molecular Characterizations of the Polysaccharide(s) from Ultrasonic-Circulating Extracts of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes).

Total polysaccharide (i.e., GLP-UCE) was effectively isolated from the crude polysaccharide extract powder of Ganoderma lucidum by ultrasonic-circulating extraction, which was separated into three fractions (i.e., GLP-U40, GLP-U60, and GLP-U80) by ethanol fractional precipitation..

Cordyceps · 2020 · Journal Article · Natural product research

Carboxymethylation and acetylation of the polysaccharide from Cordyceps militaris and their α-glucosidase inhibitory activities.

The crude polysaccharide extracted from Cordyceps militaris was chemically modified to obtain carboxymethylated derivatives (CM-CPS) and acetylated derivatives (AC-CPS)..

OncologyImmune supportCognition & nervesEnergy & fatigue

Cordyceps · 2020 · Journal Article · International journal of medicinal mushrooms

Caterpillar Medicinal Mushroom, Cordyceps militaris (Ascomycetes), Mycelia Attenuates Doxorubicin-Induced Oxidative Stress and Upregulates Krebs Cycle Dehydrogenases Activity and ATP Level in Rat Brain.

Post-chemotherapy-induced cognitive dysfunction remains one of the challenges in cancer survivors. Cytokine-induced neurotoxicity manifests in subjects at any time after doxorubicin (DOX) chemotherapy..

Cognition & nervesEnergy & fatigue

Cordyceps · 2020 · Journal Article · International journal of medicinal mushrooms

Caterpillar Medicinal Mushroom, Cordyceps militaris (Ascomycetes), Protects Aβ1-42-Induced Neurologic Damage in C6 Glial Cells.

Alzheimer's disease (AD) shows neurological symptoms common to cognitive disorders and memory loss. Several hypotheses have suggested that the accumulation of amyloid-beta peptide (Aβ) and reduction of acetylcholine synthesis cause AD..

Oyster Mushroom · 2020 · Journal Article · Journal of food science

Characterization of astragaloside I-IV based on the separation of HPTLC from Pleurotus ostreatus cultivated with Astragalus.

In this study, total saponins were extracted from Pleurotus ostreatus cultivated with Astragalus as one of organic culture substrates. High Performance Thin Layer Chromatography (HPTLC) assay showed total saponins could be separated effectively, and four kinds of spots were identified as AG I, AG II, AG III, and AG….

Cordyceps · 2020 · Journal Article · Microbial pathogenesis

Comparative analysis of the immune response of the wax moth Galleria mellonella after infection with the fungi Cordyceps militaris and Metarhizium robertsii.

Entomopathogenic fungi form different strategies of interaction with their insect hosts. The influence of fungal infection on insect physiology has mainly been studied for generalists (Metarhizium, Beauveria), but studies of specialized teleomorphic species, such as Cordyceps militaris, are rare..

Cordyceps · 2020 · Research Article · Nutrients

Cordyceps militaris Fruit Body Extract Decreases Testosterone Catabolism and Testosterone-Stimulated Prostate Hypertrophy.

The androgens testosterone and dihydrotestosterone (DHT) are essential for a variety of systemic functions in mature males. Alteration of these hormones results in late-onset hypogonadism (LOH) and benign prostate hyperplasia (BPH)..

King Oyster · 2020 · Journal Article · Biotechnology and applied biochemistry

Decolorization and degradation potential of enhanced lignocellulolytic enzymes production by Pleurotus eryngii using cherry waste from industry.

Lignocellulosic wastes accumulate in large quantities and thus cause environmental issues. Cherry waste (CW) of them collected from industry was used as the substrate to increase production of lignocellulolytic enzymes, laccase (Lac), manganese peroxidase (MnP), lignin peroxidase (LiP), carboxymethyl cellulase….

Cordyceps · 2020 · Research Article · ACS omega

Determination of Adenosine and Cordycepin Concentrations in Cordyceps militaris Fruiting Bodies Using Near-Infrared Spectroscopy.

Near-infrared (NIRS) spectroscopy, coupled with partial least squares regression, was used to predict adenosine and cordycepin concentrations in fruiting bodies of Cordyceps militaris..

Chaga · 2020 · Journal Article · International journal of medicinal mushrooms

Effects of Chaga Medicinal Mushroom Inonotus obliquus (Agaricomycetes) Extracts on NOS-cGMP-PDE5 Pathway in Rat Penile Smooth Muscle Cells.

Some medicinal mushrooms have effects on sexual dysfunctions. Nitric oxide synthase (NOS)-cyclic gua-nosine monophosphate (cGMP)-phosphodiesterase 5 enzyme (PDE5) pathway is one of the pathophysiological basis of erectile dysfunction (ED)..

OncologyImmune supportCognition & nervesEnergy & fatigue

Cordyceps · 2020 · Research Article · Biotechnology reports (Amsterdam, Netherlands)

Enhanced production of cordycepin in Ophiocordyceps sinensis using growth supplements under submerged conditions.

Cordycepin is a crucial bioactive compound produced by the fungus Cordyceps spp. Its therapeutic potential has been recognized for a wide range of biological properties such as anticancer, anti-diabetic, antidepressant, antioxidant, immunomodulation, etc..

Turkey Tail · 2020 · Journal Article · Food & function

Enhancement of the anti-inflammatory properties of grape pomace treated by Trametes versicolor.

The application of solid-state fermentation for the production of value-added products from the agro- and food-industry residues has been recently investigated greatly. The white-rot basidiomycete Trametes versicolor is a widely used fungi for the degradation lignocellulosic material in solid-state conditions..

Immune supportEnergy & fatigueMetabolic health

King Oyster · 2020 · Journal Article · International journal of food science & technology

Extraction, isolation, characterisation, antioxidant and anti‐fatigue activities of Pleurotus eryngii polysaccharides

Pleurotus eryngii polysaccharide (PEP) was obtained using hot water extraction and ethanol precipitation. Three purified polysaccharide fractions (namely PEP1‐A, PEP2‐A and PEP3‐A) were obtained from PEP using DEAE‐cellulose‐52 chromatography and a gel permeation Sephadex G‐100 column..

OncologyImmune supportEnergy & fatigueMetabolic health

Lion's Mane · 2020 · Journal Article · Food & function

Fruiting body polysaccharides of Hericium erinaceus induce apoptosis in human colorectal cancer cells via ROS generation mediating caspase-9-dependent signaling pathways.

The fruiting bodies of Hericium erinaceus (Bull.) Pers. are commonly used in China in the treatment of digestive system diseases.

Energy & fatigueRespiratory

Cordyceps · 2020 · Research Article · Sensors (Basel, Switzerland)

Implementation and Performance Evaluation of Integrated Wireless MultiSensor Module for Aseptic Incubator of Cordyceps militaris.

This paper originally proposes a wireless multisensor module with illuminance, temperature, relative humidity (RH) and carbon dioxide (CO2) sensors in an aseptic jar incubator for a solid-state fermentation (SSF) of Cordyceps militaris culture..

Immune supportEnergy & fatigueGut & microbiomeLiver support

King Oyster · 2020 · Journal Article · Food Hydrocolloids

In vitro digestion and cellular antioxidant activity of β-carotene-loaded emulsion stabilized by soy protein isolate-Pleurotus eryngii polysaccharide conjugates

β-Carotene is a natural fat-soluble antioxidant, while the poor oral bioavailability of β-carotene restricts its application for functional foods. To overcome this barrier, a stable oil-in-water emulsion was structured to effectively deliver β-carotene..

OncologyImmune supportEnergy & fatigueMetabolic health

Chaga · 2020 · Journal Article · International journal of biological macromolecules

Inonotus obliquus polysaccharides induces apoptosis of lung cancer cells and alters energy metabolism via the LKB1/AMPK axis.

The present study explores the mechanisms underlying the anti-cancer action of Inonotus obliquus polysaccharides (IOP). Thus, we characterized the IOP components extracted from Chaga sclerotium and, found that the extracts contained 70% polysaccharides with an average molecular weight of 4.5 × 104 Da consisting of 75%….

Energy & fatigueMetabolic health

Oyster Mushroom · 2020 · Journal Article · Applied microbiology and biotechnology

Lactic acid accumulation under heat stress related to accelerated glycolysis and mitochondrial dysfunction inhibits the mycelial growth of Pleurotus ostreatus.

High temperature is a major threat to Pleurotus ostreatus cultivation. In this study, a potential mechanism by which P.

Shiitake · 2020 · Journal Article · Applied microbiology and biotechnology

Latcripin-7A, derivative of Lentinula edodes C91-3, reduces migration and induces apoptosis, autophagy, and cell cycle arrest at G1 phase in breast cancer cells.

Due to the high mortality rate and an increase in breast cancer incidence, it has been challenging for researchers to come across an effective chemotherapeutic strategy with minimum side effects. Therefore, the need for the development of effective chemotherapeutic drugs is still on the verge..

OncologyEnergy & fatigue

Immune supportEnergy & fatigueGut & microbiome

Shiitake · 2020 · Research Article · Biological trace element research

Lentinula edodes as a Source of Bioelements Released into Artificial Digestive Juices and Potential Anti-inflammatory Material.

Lentinula edodes (shiitake), an edible and medicinal mushroom, was chosen for this study with the aim of evaluating the possibility of release of bioelements into artificial digestive juices and analyzing the anti-inflammatory properties..

Cognition & nervesEnergy & fatigueMetabolic health

Reishi · 2020 · Journal Article · International journal of medicinal mushrooms

Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes) Ameliorates Spatial Learning and Memory Deficits in Rats with Hypercholesterolemia and Alzheimer's Disease.

Hypercholesterolemia has been implicated as one of the pathomechanistic factors of Alzheimer's disease (AD), the most common neurodegenerative disorder affecting memory and learning abilities..

OncologyImmune supportEnergy & fatigueMetabolic health

Chaga · 2020 · Research Article · Scientific reports

Molecular insights and cell cycle assessment upon exposure to Chaga (Inonotus obliquus) mushroom polysaccharides in zebrafish (Danio rerio).

Chaga (Inonotus obliquus) mushroom is considered as one of the most powerful antioxidants across the world. Though the therapeutic effects of Chaga components are well characterized in vitro, the in vivo developmental effects are not elucidated in detail..

Wood Ear · 2020 · Journal Article · International journal of biological macromolecules

Phagocytosis enhancement, endotoxin tolerance, and signal mechanisms of immunologically active glucuronoxylomannan from Auricularia auricula-judae.

Glucuronoxylomannan (AAPS) from the edible wood ear mushroom Auricularia auricula-judae has been demonstrated to exhibit immunostimulatory properties through its binding to TLR4. However, the mechanisms of immune modulation by AAPS in mammalian cells remains unclear..

Immune supportEnergy & fatigueMetabolic health

Snow Fungus · 2020 · Journal Article · International journal of biological macromolecules

Production, structure, and bioactivity of polysaccharide isolated from Tremella fuciformis XY.

Tremella fuciformis polysaccharide (TFP) is an important bioactive substance in Tremella, that contributes to its use as medicine and food. In this study, a novel fungus Tremella fuciformis XY was isolated and introduced to produce macromolecule polysaccharides (TFPB)..

OncologyImmune supportEnergy & fatigue

Maitake · 2020 · Journal Article · Glycoconjugate journal

Relationship between heat treatment on structural properties and antitumor activity of the cold-water soluble polysaccharides from Grifola frondosa.

Grifola frondosa is a basidiomycete fungus with potential biomedical applications owing to the presence of bioactive polysaccharides. The activities of polysaccharides are influenced by many factors, particularly temperature; however, the optimal temperature and conditions for preparation of polysaccharides from this….

King Oyster · 2020 · Research Article · Molecules (Basel, Switzerland)

Selenium and Zinc Biofortification of Pleurotus eryngii Mycelium and Fruiting Bodies as a Tool for Controlling Their Biological Activity.

Pleurotus eryngii (DC:Fr.) Quel. is a cultivated mushroom of high culinary value and medicinal properties.

Immune supportCognition & nervesEnergy & fatigueMetabolic health

Chaga · 2020 · Journal Article · International journal of biological macromolecules

Spatial structure and anti-fatigue of polysaccharide from Inonotus obliquus.

The aim of this study was to evaluate the spatial structure and potential antifatigue activity of polysaccharide fractions which was extracted from Inonotus obliquus..

OncologyImmune supportEnergy & fatigueLiver support

Maitake · 2020 · Journal Article · International journal of biological macromolecules

The caspases-dependent apoptosis of hepatoma cells induced by an acid-soluble polysaccharide from Grifola frondosa.

The edible mushroom Grifola frondosa has been used as a functional food for diseases prevention and therapy in Asian countries. In the present work, an acid-soluble polysaccharide (GFAP) was prepared from Grifola frondosa under room temperature and hydrochloric acid solution treatment, and its inhibitory effects on….

Cordyceps · 2020 · Research Article · Frontiers in microbiology

Transcriptome Analysis Reveals the Flexibility of Cordycepin Network in Cordyceps militaris Activated by L-Alanine Addition.

Cordycepin, isolated from the traditional medicinal fungus Cordyceps militaris, has gained much attention due to its various clinical functions. Previous reports of L-alanine addition could significantly improve cordycepin production, but the molecular mechanism remains unknown..

Cordyceps · 2020 · Journal Article · Biomedical chromatography: BMC

UPLC-ESI-Q-TOF-MS/MS analysis of anticancer fractions from Ophiocordyceps xuefengensis and Ophiocordyceps sinensis.

Ophiocordyceps xuefengensis (O. xuefengensis), a new species of caterpillar fungus, has been identified as the sister taxon of Ophiocordyceps sinensis (O.

OncologyEnergy & fatigue

Immune supportEnergy & fatigueGut & microbiomeLiver support

Cordyceps · 2020 · Journal Article · Food & function

Using Cordyceps militaris extracellular polysaccharides to prevent Pb2+-induced liver and kidney toxicity by activating Nrf2 signals and modulating gut microbiota.

In this study, we investigated the protective efficacy of extracellular polysaccharide from Cordyceps militaris (CEP-I) in liver and kidney and their regulating effect on gut microbiota against Pb-induced toxicity in vivo..

Oyster Mushroom · 2020 · Research Article · Saudi journal of biological sciences

Variation of Pleurotus ostreatus (Jacq. Ex Fr.) P. Kumm. (1871) performance subjected to differentdoses and timings of nano-urea.

Supplementation of the growing substrate by nitrogenous additives has been known to improve the production of oyster mushroom (Pleurotus ostreatus (Jacq. ex Fr.) P.

OncologyImmune supportCognition & nervesEnergy & fatigue

Mesima · 2020 · Research Article · Molecules (Basel, Switzerland)

Vasodilatory Effect of Phellinus linteus Extract in Rat Mesenteric Arteries.

Phellinus linteus is a well-known medicinal mushroom that is widely used in Asian countries. In several experimental models, Phellinus linteus extracts were reported to have various biological effects, including anti-inflammatory, anti-cancer, hepatoprotective, anti-diabetic, neuroprotective, and anti-angiogenic….

OncologyCognition & nervesEnergy & fatigue

Reishi · 2020 · Research Article · Molecules (Basel, Switzerland)

Water-Extracted Ganoderma lucidum Induces Apoptosis and S-Phase Arrest via Cyclin-CDK2 Pathway in Glioblastoma Cells.

Glioblastoma is one of the most common and most aggressive brain cancers. The current treatment is mainly surgery, chemotherapy, and radiation therapy, but the results are not satisfactory.

Cordyceps · 2019 · Journal Article · Sheng wu gong cheng xue bao = Chinese journal of biotechnology

[Production of antioxidative exopolysaccharides of Cordyceps militaris with Vernonia amygdalina leaves in substrate].

Cordyceps militaris exopolysaccharides (EPS) have many pharmacological activities such as boosting immunity and antifatigue. To obtain EPS efficiently, we added moderate Vernonia amygdalina leaf powder as inducer to the fermentation medium to promote the production of Cordyceps militaris EPS and studied the infrared….

OncologyImmune supportEnergy & fatigueLiver support

Maitake · 2019 · Journal Article · International journal of biological macromolecules

A cold-water soluble polysaccharide isolated from Grifola frondosa induces the apoptosis of HepG2 cells through mitochondrial passway.

Grifola frondosa is a widely eaten and medicinal fungus. In this study, we extracted a cold-water-soluble polysaccharide from Grifola frondosa (cGFP) and investigated its effects on the proliferation and apoptosis of human hepatoma HepG2 cells..

OncologyEnergy & fatigueMetabolic health

Cordyceps · 2019 · Journal Article · Fitoterapia

A new cerebroside from cordyceps militaris with anti-PTP1B activity.

Cordyceps militaris (L.) Link (C. militaris) has been used as a folk medicine for treatment of various diseases in China and some other countries.

Cordyceps · 2019 · Journal Article · Innovative Food Science and Emerging Technologies

A novel infrared freeze drying (IRFD) technology to lower the energy consumption and keep the quality of Cordyceps militaris

A novel laboratory scale apparatus using infrared lamps replacing the electric heating plate for the freeze drying of Cordyceps militaris was developed in this study..

Cordyceps · 2019 · Journal Article · International journal of food science & technology

A simple and effective method using macroporous resins for the simultaneous decoloration and deproteinisation of Cordyceps militaris polysaccharides

The aim of this study was to develop an effective one‐step decoloration and deproteinisation method using macroporous resin for Cordyceps militaris polysaccharide (CMP) extraction..

Cordyceps · 2019 · Journal Article · International journal of medicinal mushrooms

Antioxidant-Rich Peptide Fractions Derived from High-Altitude Chinese Caterpillar Medicinal Mushroom Ophiocordyceps sinensis (Ascomycetes) Inhibit Bacterial Pathogens.

Ophiocordyceps sinensis (=Cordyceps sinensis), a medicinal mushroom native to the Orient, has been extensively used for the past few centuries in traditional Chinese medicine because of its immunomodulatory, antiinflammatory, and nutraceutical properties..