MycoData

Laccase is an extracellular enzyme that is widely used in the decolonization of textile dyes in waste water. The aim of our study was to isolate, purify, characterize and immobilize the laccase enzyme produced by Trametes versicolor HBB 7328..

Gut & microbiome

High relevance

Cordyceps · 2024 · Research Article · Frontiers in pharmacology

Protective effects of Cordyceps militaris against hepatocyte apoptosis and liver fibrosis induced by high palmitic acid diet.

BACKGROUND: Fatty Liver Disease (FLD) progresses from steatosis to steatohepatitis and, if left untreated, can lead to irreversible conditions such as cirrhosis and hepatocarcinoma. The etiology of FLD remains unclear, but factors such as overconsumption, poor diet, obesity, and diabetes contribute to its development..

OncologyImmune supportEnergy & fatigueMetabolic health

High relevance

Cordyceps · 2024 · Journal Article · Current microbiology

Proteomic Analysis Reveals Differentially Expressed Proteins in Cordyceps militaris Cultured with Different Media.

Cordyceps militaris is rich in high quality protein, which is an excellent protein supplement. In this study, proteins were extracted from C.

Immune supportMetabolic health

High relevance

Cordyceps · 2024 · Research Article · Journal of Ayurveda and integrative medicine

Quest for Anti-SARS-CoV-2 antiviral therapeutics: in-silico and in-vitro analysis of edible mushroom- Cordyceps militaris.

BACKGROUND: The emergence and evolution of SARS-CoV-2 resulted a severe threat to public health globally. Due to the lack of an effective vaccine with durable immunity, the disease transited into the endemic phase, necessitating potent antiviral therapy including a scientific basis for current traditional herbal….

Immune supportRespiratory

High relevance

Chaga · 2024 · Journal Article · Journal of separation science

Rapid screening and isolation of 5-lipoxygenase inhibitors in Inonotus obliquus and mechanism of action in the treatment of asthma.

Accurate screening and targeted preparative isolation of active substances in natural medicines have long been two technical challenges in natural medicine research..

Energy & fatigueRespiratory

High relevance

Shiitake · 2024 · Review · Frontiers in nutrition

Recent advances and role of melatonin in post-harvest quality preservation of shiitake (Lentinula edodes).

Shiitake mushrooms are renowned for their popularity and robust nutritional value, are susceptible to spoilage due to their inherent biodegradability. Nevertheless, because of their lack of protection, these mushrooms have a short shelf life..

High relevance

Reishi · 2024 · Review · Heliyon

Research progress of Ganoderma lucidum polysaccharide in prevention and treatment of Atherosclerosis.

Atherosclerosis (AS) is a chronic inflammatory disease resulting from dysregulated lipid metabolism, constituting the pathophysiological foundation of cardiovascular and cerebrovascular diseases. AS has a high incidence rate and mortality rate worldwide..

Immune supportMetabolic healthGut & microbiome

High relevance

Lion's Mane · 2024 · Preprint · journal metadata

Role of Hericium Erinaceus as a Probiotic Stimulant

Abstract Lion's Mane mushroom ( Hericium erinaceus ) is gaining scientific interest for its potential health benefits, particularly its bioactive compounds and probiotic-stimulatory properties..

Immune supportGut & microbiome

High relevance

Cordyceps · 2024 · Research Article · Antioxidants (Basel, Switzerland)

Sea Cucumber Viscera Processed by Protease Hydrolysis Combined with Cordyceps militaris Fermentation Protect Caco-2 Cells against Oxidative Damage via Enhancing Antioxidant Capacity, Activating Nrf2/HO-1 Pathway and Improving Cell Metabolism.

Excessive reactive oxygen species (ROS) may lead to oxidative damage and metabolic disorder. The pathogenesis of human bowel inflammation is closely related to oxidative damage of intestinal epithelial cells caused by ROS..

OncologyImmune supportEnergy & fatigueMetabolic health

High relevance

Shiitake · 2024 · Journal Article · Journal of food composition and analysis

Selenium speciation analysis of selenium-enriched Shiitake mushrooms (Lentinula edodes) by HPLC-ESI-MS

Selenium (Se) is an essential component of critical enzymes and is intricately linked to human health. Shiitake mushrooms (Lentinula edodes) are considered as good dietary supplements for producing Se-enriched foods due to their high protein content and ability to absorb minerals from growth substrates..

Energy & fatigueGut & microbiome

High relevance

Shiitake · 2024 · Journal Article · Carbohydrate polymers

Simulated human digestion and fermentation of a high-molecular weight polysaccharide from Lentinula edodes mushroom and protective effects on intestinal barrier

Lentinula edodes (Shiitake) is an important edible mushroom and polysaccharides are its major constituents with proven health benefits. The study was to investigate the gut bacterial fermentation and subsequent effects on gut barrier function of a glucan-rich polysaccharide, LePS40 precipitated from the mushroom water….

OncologyImmune supportMetabolic healthGut & microbiome

High relevance

Cordyceps · 2024 · Preprint · journal metadata

Solid-state fermentation product of Cordyceps militaris enhances the antioxidation and modulates immune response in grower pigs

Abstract Background: Pathogenic infections can significantly impact the health of livestock. Traditionally, antibiotic growth promoters (AGPs) have been used in feed to enhance growth performance and disease control..

OncologyImmune supportEnergy & fatigueGut & microbiome

High relevance

Reishi · 2024 · Research Article · Frontiers in pharmacology

Sporoderm-removed Ganoderma lucidum spores ameliorated early depression-like behavior in a rat model of sporadic Alzheimer's disease.

Introduction: Ganoderma lucidum: (G. lucidum, Lingzhi) is a medicinal and edible homologous traditional Chinese medicine that is used to treat various diseases, including Alzheimer's disease and mood disorders.

Immune supportCognition & nerves

High relevance

King Oyster · 2024 · Research Article · Foods (Basel, Switzerland)

Steam Explosion-Assisted Extraction of Polysaccharides from Pleurotus eryngii and Its Influence on Structural Characteristics and Antioxidant Activity.

Pleurotus eryngii (PE) has been sought after for its various health benefits and high content of phenolic compounds. This study explored the feasibility of steam explosion (SE)-assisted extraction of polysaccharides with high antioxidant capacities from PE..

Immune supportMetabolic health

High relevance

Reishi · 2024 · Review · International journal of medicinal mushrooms

Strategies to Increase the Production of Triterpene Acids in Ligzhi or Reishi Medicinal Mushroom (Ganoderma lucidum, Agaricomycetes): A Review.

Ganoderic acids (GAs) are the main active ingredient of Ganoderma lucidum, which has been widely accepted as a medicinal mushroom. Due to the low yield of GAs produced by liquid cultured Ganoderma mycelium and solid cultured fruiting bodies, the commercial production and clinical application of GAs are limited..

High relevance

Cordyceps · 2024 · Journal Article · International journal of biological macromolecules

Structural characteristics and anti-tumor activity of alcohol-precipitated polysaccharides from Cordyceps militaris under different ethanol concentrations.

Six Cordyceps militaris polysaccharides (named CMP-1, CMP-2, CMP-3, CMP-4, CMP-9, and CMP-A) were obtained by fractional alcohol precipitation. The experimental results showed that the six Cordyceps militaris polysaccharides had similar chemical composition and spectral features, and different molecular weights,….

OncologyImmune supportMetabolic health

High relevance

Maitake · 2024 · Journal Article · Carbohydrate research

Structural characterization and immunomodulatory effect of a starch-like Grifola frondosa polysaccharides on cyclophosphamide-induced immunosuppression in mice.

In this study, a pure Grifola frondosa polysaccharide (GFP-1) was extracted and purified from Grifola frondosa. By HPLC, GC-MS, FT-IR, and NMR analysis, GFP-1 was determined to be a starch-like polysaccharide with an average molecular weight of 3370 kDa..

Immune supportMetabolic healthGut & microbiome

High relevance

Cordyceps · 2024 · Research Article · Polymers

Structural Elucidation and Anti-Tumor Activity of a Polysaccharide (CP2-S) from Cordyceps militaris Fruit Bodies.

A polysaccharide (CP2-S), consisting of glucose with a weight average molecular weight of 5.9 × 106, was purified from the fruit bodies of Cordyceps militaris. In this work, the corresponding structure and anti-tumor activity in vivo were investigated..

OncologyImmune supportMetabolic healthRespiratory

High relevance

Reishi · 2024 · Journal Article · Carbohydrate research

Structural variety of glucans from Ganoderma lucidum fruiting bodies.

Ganoderma lucidum, widely used in traditional medicine, has several biological properties. Polysaccharides, mainly glucans, are known as one of its main bioactive compounds.

Immune support

High relevance

Reishi · 2024 · Research Article · Molecules (Basel, Switzerland)

Structure Identification of Ganoderma lucidum Spore Polysaccharides and Their Antitumor Activity In Vivo.

Ganoderma lucidum spore powder, valued for its nutritional and medicinal properties, contains polysaccharides crucial for its efficacy. However, the complex structural nature of these polysaccharides necessitates further investigation to fully realize their potential..

OncologyImmune supportGut & microbiomeLiver support

High relevance

Cordyceps · 2024 · Research Article · BMC veterinary research

Synergistic fermentation of Cordyceps militaris and herbal substrates boosts grower pig antioxidant and immune function.

BACKGROUND: Pathogenic infections can significantly impact the health of livestock. Traditionally, antibiotic growth promoters (AGPs) have been used in feed to enhance growth performance and disease control..

OncologyImmune supportEnergy & fatigueGut & microbiome

High relevance

Reishi · 2024 · Clinical Trial Protocol · BMC complementary medicine and therapies

Synergy of de-walled Ganoderma Lucidum spore powder (GLSP) on targeted therapy in advanced non-squamous non-small cell lung cancer with epidermal growth factor receptor (EGFR) mutant: protocol for a randomized, double-blind, placebo-controlled study.

BACKGROUND: Osimertinib is regarded as a promising third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) for advanced non-squamous non-small cell lung cancer (NSCLC) patients who developed T790M..

OncologyImmune supportEnergy & fatigueGut & microbiome

High relevance

Reishi · 2024 · Research Article · Heliyon

The anti-fatigue and sleep-aiding effects vary significantly among different recipes containing Ganoderma lucidum extracts.

AIMS: This study aims to delve into the anti-fatigue and sleep-aiding effects of various formulations containing Ganoderma lucidum extracts. MATERIALS AND METHODS: PGB [incorporating Ganoderma lucidum extract (GE), broken Ganoderma lucidum spore powder (GB) and Paecilomyces hepiali mycelium (PH)] and GBS [composed of….

Cognition & nervesEnergy & fatigueLiver support

High relevance

Reishi · 2024 · Review · Molecules (Basel, Switzerland)

The Biological Activity of Ganoderma lucidum on Neurodegenerative Diseases: The Interplay between Different Active Compounds and the Pathological Hallmarks.

Neurodegenerative diseases represent a cluster of conditions characterized by the progressive degeneration of the structure and function of the nervous system. Despite significant advancements in understanding these diseases, therapeutic options remain limited..

Immune supportCognition & nerves

High relevance

Wood Ear · 2024 · Research Article · Journal of microbiology and biotechnology

The Biphasic Activity of Auricularia Auricula-Judae Extract on Bone Homeostasis through Inhibition of Osteoclastogenesis and Modulation of Osteogenic Activity.

Osteoporosis arises from the disturbance of bone homeostasis, a process regulated by osteoblasts and osteoclasts. The treatment and prevention of bone metabolic disorders resulting from an imbalance in bone homeostasis require the use of agents that effectively promote both bone formation and anti-resorptive effects..

OncologyMetabolic health

High relevance

King Oyster · 2024 · Research Article · Food science & nutrition

The effect of in vitro digestion on the interaction between polysaccharides derived from Pleurotus eryngii and intestinal mucus.

Pleurotus eryngii polysaccharides (PEPs) have been proven to display multiple activities through digestive system action, from which the digestion products should first interact with intestinal mucus (MUC), followed by the function of intestinal cells..

Immune supportEnergy & fatigueGut & microbiome

High relevance

Reishi · 2024 · Research Article · Foods (Basel, Switzerland)

The Impact of Ganoderma lucidum (Curtis) P. Karst. Supplementation on the Technological, Chemical, and Quality Parameters of Wheat Bread.

This study explores the incorporation of Ganoderma lucidum (Curtis) P. Karst.

High relevance

Lion's Mane · 2024 · Journal Article · International journal of medicinal mushrooms

The Influence of Polysaccharide Fractions of the Lion's Mane Medicinal Mushroom Hericium erinaceus (Agaricomycetes) on the Immunomodulatory and Antioxidant Activity of Neutrophils Exposed to Stress of Different Durations.

Polysaccharide fractions from the mycelium of the lion's mane medicinal mushroom Hericium erinaceus BP 16, cultivated on sterile grain substrates (barley, oats, wheat, rice, rye), were isolated and characterized..

Immune support

High relevance

Oyster Mushroom · 2024 · Preprint · journal metadata

The Niger Delta is Under a Pollution Warning: Hydrocarbon profiles in crude oil polluted soil remediated with Pleurotus ostreatus and Eisenia fitida

Rationale: The contamination of soil with crude oil poses significant environmental and ecological threats. Bioremediation, particularly through the use of organisms like Pleurotus ostreatus (mushroom) and Eisenia fetida (earthworm), has emerged as a promising approach to mitigate crude oil pollution..

High relevance

Lion's Mane · 2024 · Review · Journal of physiology and pharmacology: an official journal of the Polish Physiological Society

The potential therapeutic role of Hericium erinaceus extract in pathologic conditions involving the urogenital-gut axis: insights into the involved mechanisms and mediators.

In this review we focused on the putative therapeutic effect of Hericium erinaceus extract in the treatment of pathologic conditions of the lower urinary tract in which intestinal inflammation may play a role..

Immune supportGut & microbiome

High relevance

Reishi · 2024 · Research Article · Toxics

The Protective Effects of Ganoderma lucidum Active Peptide GLP4 on Lung Injury Induced by Cadmium Poisoning in Mice.

Ganoderma triterpenes and spore powder have shown promising results in mitigating cadmium-induced renal and hepatic injuries. Ganoderma lucidum active peptide GLP4 is a natural protein with dual antioxidant activities derived from the mycelium of Ganoderma lucidum..

Immune supportLiver supportRespiratory

High relevance

Cordyceps · 2024 · Research Article · Journal of fungi (Basel, Switzerland)

The Stress of Fungicides Changes the Expression of Clock Protein CmFRQ and the Morphology of Fruiting Bodies of Cordyceps militaris.

The physiological, biochemical, and morphological changes brought about by fungi in response to fungicides can undoubtedly bring diversity to fungi. Cordyceps militaris strains TN (mating type genes MAT1-1-1, MAT1-1-2, and MAT1-2-1) and CmFRQ-454 (mating type genes MAT1-1-1 and MAT1-1-2) were treated with non-lethal….

High relevance

Chaga · 2024 · Review · Mycology

Therapeutic properties of Inonotus obliquus (Chaga mushroom): A review.

Inonotus obliquus, also known as Chaga, is a medicinal mushroom that has been used for therapeutic purposes since the sixteenth century. Collections of folk medicine record the application of Chaga for the treatment of diseases such as gastrointestinal cancer, diabetes, bacterial infection, and liver diseases..

OncologyImmune supportEnergy & fatigueMetabolic health

High relevance

Shiitake · 2024 · Journal Article · Trends in food science & technology

Therapeutic values and nutraceutical properties of shiitake mushroom (Lentinula edodes): A review

Mushrooms are generally regarded as useful products with multiple applications in the food and health industry. Shiitake (Lentinula edodes) is one of the most cultured and consumed mushrooms around the world..

OncologyImmune supportMetabolic healthLiver support

High relevance

Reishi · 2024 · Journal Article · Animal science journal = Nihon chikusan Gakkaiho

Time-dependent change in Reishi (Ganoderma lingzhi) triterpenoids in culture with rumen fluid.

The purpose of this study was to investigate the time-dependent change in Reishi (Ganoderma lingzhi) triterpenoids in rumen fluid. G.

Metabolic healthGut & microbiome

High relevance

Reishi · 2024 · Journal Article · Animal science journal =

Time‐dependent change in Reishi (Ganoderma lingzhi) triterpenoids in culture with rumen fluid

The purpose of this study was to investigate the time‐dependent change in Reishi (Ganoderma lingzhi) triterpenoids in rumen fluid. G.

Metabolic healthGut & microbiome

High relevance

Snow Fungus · 2024 · Journal Article · Advances in clinical and experimental medicine: official organ Wroclaw Medical University

Transcriptome analysis of immune-inflammatory regulation in Tremella fuciformis-derived polysaccharide reeducated B16 cells: A subcutaneous model.

BACKGROUND: Circulating cancer cells have characteristics of tumor self-targeting. Modified circulating tumor cells may serve as tumor-targeted cellular drugs.

OncologyImmune supportLiver support

High relevance

King Oyster · 2024 · Research Article · Journal of fungi (Basel, Switzerland)

Transcriptome Analysis of the Growth-Promoting Effect of Large Macrofungal Sclerotium Powder on Lentinula edodes and Pleurotus eryngii Strains.

In the industrial production of Lentinula edodes and Pleurotus eryngii, slow growth of the mother seed and insufficient hyphal vitality can significantly affect the cultivation process. To shorten the growth period on traditional PDA medium, two strains of L.

Energy & fatigueMetabolic health

High relevance

Oyster Mushroom · 2024 · Research Article · International journal of molecular sciences

Transcriptome Analysis Reveals the Effect of Oyster Mushroom Spherical Virus Infection in Pleurotus ostreatus.

Oyster mushroom spherical virus (OMSV) is a mycovirus that inhibits mycelial growth, induces malformation symptoms, and decreases the yield of fruiting bodies in Pleurotus ostreatus. However, the pathogenic mechanism of OMSV infection in P.

Metabolic healthRespiratory

High relevance

Cordyceps · 2024 · Research Article · Animals: an open access journal from MDPI

Transcriptomic and Metabolomic Analyses Reveal the Attenuating Role of Cordycepin and Cordyceps militaris Extract on Acute Liver Injury Induced by LPS in Piglets.

Cordyceps militaris extract (CME) contains many bioactive compounds, mainly cordycepin (CPN). This study aimed to investigate the possible mechanisms underlying the amelioration of LPS-induced acute liver injury in piglets by CME or CPN supplementation using multi-omics analysis..

Immune supportLiver support

High relevance

Snow Fungus · 2024 · Research Article · BMC nutrition

Tremella fuciformis beverage improves glycated hemoglobin A1c and waist circumference in overweight/obese prediabetic subjects: a randomized controlled trial.

BACKGROUND: Prediabetes is increasing worldwide. Previous studies have demonstrated the potential of β-glucan derived from oat or barley to lower blood glucose, body weight, and plasma lipid levels.

Metabolic health

High relevance

Cordyceps · 2024 · Journal Article · Crop protection

Trichoderma gamsii, a new pathogen causing disease on cultivated mushroom Cordyceps militaris in China

The fungal disease of Cordyceps militaris has become the primary disease during the cultivation of C. militaris.

High relevance

Cordyceps · 2024 · Research Article · Molecules (Basel, Switzerland)

Ultrasound-Assisted Enzyme Extraction, Physicochemical Properties and Antioxidant Activity of Polysaccharides from Cordyceps militaris Solid Medium.

Cordyceps militaris solid medium polysaccharides (CMMPs) were extracted using an ultrasound-assisted enzyme method, and the process conditions were optimized via response surface methodology (RSM)..

Immune supportMetabolic healthSkin & hydration

High relevance

Cordyceps · 2024 · Research Article · Frontiers in microbiology

Unveiling mycoviral diversity in Ophiocordyceps sinensis through transcriptome analyses.

Ophiocordyceps sinensis, an entomopathogenic fungus, infects larvae from the Lepidoptera: Hepialidae family, forming the valuable Chinese cordyceps. Mycoviruses are widespread across major lineages of filamentous fungi, oomycetes, and yeasts and have the potential to influence fungal biology and ecology..

Respiratory

High relevance

Shiitake · 2024 · Research Article · Heliyon

Valorization of agro-forest wastes (oak acorns, vineyard pruning, and olive pruning) through the cultivation of shiitake (Lentinula edodes) mushrooms.

Experimental research has been focusing on developing new substrates for growing shiitake mushrooms as alternatives to the standard oak sawdust substrate. The selection of appropriate lignocellulosic materials is based on their availability in the production area and their compatibility with the requirements of the….

High relevance

King Oyster · 2024 · Research Article · Life (Basel, Switzerland)

Valorization of Ginkgo biloba Leaf Powder as a Substrate in King Oyster Mushroom (Pleurotus eryngii) Cultivation.

Ginkgo biloba is widely planted as a colorful foliage tree, and its leaf can be used as a biomass energy source, but it has been underutilized for a long time. The aim of this study was to investigate the potential of garden waste as a substrate component in the cultivation process of the king oyster mushroom….

Energy & fatigueGut & microbiome

High relevance

Cordyceps · 2024 · Research Article · Molecules (Basel, Switzerland)

Verification of In Vitro Anticancer Activity and Bioactive Compounds in Cordyceps Militaris-Infused Sweet Potato Shochu Spirits.

Many liqueurs, including spirits infused with botanicals, are crafted not only for their taste and flavor but also for potential medicinal benefits. However, the scientific evidence supporting their medicinal effects remains limited..

OncologyEnergy & fatigueGut & microbiome

High relevance

Cordyceps · 2024 · Research Article · International journal of molecular sciences

Visualized Nucleic Acid Hybridization Lateral Flow Strip Integrating with Microneedle for the Point-of-Care Authentication of Ophiocordyceps sinensis.

Due to the price and demand of Ophiocordyceps sinensis having increased dramatically, adulteration with other fungi is a common problem. Thus, a reliable method of authentic O.

High relevance

Reishi · 2023 · Review · International journal of biological macromolecules

A novel promising neuroprotective agent: Ganoderma lucidum polysaccharide.

Nervous system diseases (NSDs) are characterized by a wide range of symptoms, a complex pathophysiology, an unclear etiology, a great deal of variation in treatment response, and lengthy therapy cycles, all of which pose considerable hurdles to clinical treatment..

OncologyImmune supportCognition & nervesLiver support

High relevance

King Oyster · 2023 · Review · Foods (Basel, Switzerland)

Advances in Postharvest Storage and Preservation Strategies for Pleurotus eryngii.

The king oyster mushroom (Pleurotus eryngii) is a delicious edible mushroom that is highly prized for its unique flavor and excellent medicinal properties. Its enzymes, phenolic compounds and reactive oxygen species are the keys to its browning and aging and result in its loss of nutrition and flavor..

Energy & fatigue