MycoData

Age-related loss of function brings age-related disease, and therefore it is of primary importance to search for interventions that can help minimize detrimental symptoms people deal with in old age..

Immune supportCognition & nerves

Medium relevance

Almond Mushroom · 2023 · Randomized Controlled Trial · Scientific reports

Reduction in sugar drink valuation and consumption with gamified executive control training.

The overvaluation of high-energy, palatable food cues contributes to unhealthy eating and being overweight. Reducing the valuation of unhealthy food may thus constitute a powerful lever to improve eating habits and conditions characterized by unhealthy eating..

Cognition & nervesEnergy & fatigue

Medium relevance

Agarikon · 2022 · Review · Environmental chemistry letters

Old growth forests and large old trees as critical organisms connecting ecosystems and human health. A review.

Old forests containing ancient trees are essential ecosystems for life on earth. Mechanisms that happen both deep in the root systems and in the highest canopies ensure the viability of our planet..

Cognition & nervesEnergy & fatigueRespiratory

Medium relevance

Lion's Mane · 2021 · Review · Bioscience, biotechnology, and biochemistry

Chemical studies on bioactive compounds related to higher fungi.

Hericium erinaceus (Yamabushitake in Japan) is a well-known edible and medicinal mushroom. We discovered antidementia compounds, hericenones C to H, from the fruiting bodies and erinacine A to I from the cultured mycelia of the fungus..

Cognition & nervesMetabolic health

Medium relevance

Cordyceps · 2021 · Review · Food & function

Dietary agents in mitigating chemotherapy-related cognitive impairment (chemobrain or chemofog): first review addressing the benefits, gaps, challenges and ways forward.

Chemobrain or chemofog is one of the important but less investigated side effects, where the cancer survivors treated with chemotherapy develop long-term cognitive impairments, affecting their quality of life. The biological mechanisms triggering the development of chemobrain are largely unknown..

OncologyImmune supportCognition & nerves

Medium relevance

Cordyceps · 2026 · Preprint · journal metadata

Fungal Cordyceps Nucleosides and Analogs as Potential PD-L1 Inhibitors as Anti-Glioblastoma: An In Silico Multiparameter Optimization (MPO) Design

Immune checkpoint modulation has emerged as a promising strategy in cancer therapy, including the treatment of aggressive tumors such as glioblastoma. Among these targets, programmed death-ligand 1 (PD-L1) plays a key role in tumor immune evasion and represents an attractive target for small-molecule inhibitor….

OncologyImmune supportCognition & nervesEnergy & fatigue

Medium relevance

Reishi · 2026 · Systematic Review · The international journal of neuropsychopharmacology

The efficacy of nutritional phytochemical compounds in improving cognition.

The incidence of cognitive disorders is rising, and medications to address cognitive impairments are limited. Phytochemical compounds have had some success in improving cognitive outcomes in preclinical studies..

Cognition & nervesEnergy & fatigue

Medium relevance

Reishi · 2023 · Research Article · Aging medicine (Milton (N.S.W))

Ganoderic Acid A targeting leucine-rich repeat kinase 2 involved in Parkinson's disease-A computational study.

OBJECTIVE: This study aims to find the most promising Ganoderma lucidium targeting LRRK2 involved in PD. METHODS: First ADMET analysis was performed for five compounds followed by molecular docking of each compound..

OncologyCognition & nervesLiver support

Medium relevance

Lion's Mane · 2022 · Research Article · International journal of molecular sciences

Erinacine A Prevents Lipopolysaccharide-Mediated Glial Cell Activation to Protect Dopaminergic Neurons against Inflammatory Factor-Induced Cell Death In Vitro and In Vivo.

Hericium erinaceus (HE) is a common edible mushroom consumed in several Asian countries and considered to be a medicinal mushroom with neuroprotective effects. Erinacine A (EA) is a bioactive compound in Hericium erinaceus mycelium (HEM) that has been shown to have a neuroprotective effect against neurodegenerative….

Immune supportCognition & nerves

Medium relevance

Cordyceps · 2024 · Journal Article · Journal of Asian natural products research

Cordycepin, a bioactive compound from Cordyceps spp., moderates Alzheimer's disease-associated pathology via anti-oxidative stress and autophagy activation.

Alzheimer's causes cognitive dysfunction. This study investigated the neuro-promoting effects of cordycepin on amyloid-beta precursor protein (APP) synthesis in human neuroblastoma SH-SY5Y cells.

Cognition & nerves

Medium relevance

Cordyceps · 2024 · Journal Article · Acta crystallographica. Section C, Structural chemistry

Structure and absolute configuration of natural fungal product beauveriolide I, isolated from Cordyceps javanica, determined by 3D electron diffraction.

Beauveriolides, including the main beauveriolide I {systematic name: (3R,6S,9S,13S)-9-benzyl-13-[(2S)-hexan-2-yl]-6-methyl-3-(2-methylpropyl)-1-oxa-4,7,10-triazacyclotridecane-2,5,8,11-tetrone, C27H41N3O5}, are a series of cyclodepsipeptides that have shown promising results in the treatment of Alzheimer's disease and….

Cognition & nerves

Medium relevance

Lion's Mane · 2023 · Systematic Review · The International journal of neuroscience

Effect of nutritional supports on malnutrition, cognition, function and biomarkers of Alzheimer's disease: a systematic review.

AIM: To summarize the nutritional supplementation on biochemical parameters, cognition, function, Alzheimer's Disease (AD) biomarkers and nutritional status. MATERIALS AND METHODS: PubMed, Web of Science, Korean Journal Database, Russian Science Citation Index, SciELO Citation Index, Cochrane Library and Scopus….

Cognition & nervesSkin & hydration

Medium relevance

Lion's Mane · 2018 · Published Erratum · Evidence-based complementary and alternative medicine: eCAM

Corrigendum to "Peripheral Nerve Regeneration Following Crush Injury to Rat Peroneal Nerve by Aqueous Extract of Medicinal Mushroom Hericium erinaceus (Bull.: Fr) Pers. (Aphyllophoromycetideae)".

[This corrects the article DOI: 10.1093/ecam/neq062.]..

Cognition & nerves

Medium relevance

Cordyceps · 2014 · Journal Article · Mycoscience

Cloning and analysis of the Oswc-1 gene encoding a putative blue light photoreceptor from Ophiocordyceps sinensis

Light plays an important role during both sexual and asexual growth of Ophiocordyceps sinensis, one of the best-known traditional Chinese medicines. In the present study, we cloned Oswc-1, the homologue of the blue light photoreceptor Ncwc-1 of Neurospora crassa, from O.

Cognition & nervesEnergy & fatigue

Medium relevance

Oyster Mushroom · 2013 · Journal Article · Bioscience, Biotechnology, and Biochemistry

The Inhibition of Human Tumor Cell Proliferation by RNase Pol, a Member of the RNase T1 Family, from Pleurotus ostreatus

RNase Po1 is a guanylic acid-specific ribonuclease (a RNase T1 family RNase) from Pleurotus ostreatus. We determined the cDNA sequence encoding RNase Po1 and expressed RNase Po1 in Escherichia coli..

OncologyCognition & nerves

Medium relevance

Reishi · 2010 · Journal Article · Journal of Pharmacological Sciences

Inhibitory Effects of the Methanol Extract of Ganoderma lucidum on Mosquito Allergy–Induced Itch-Associated Responses in Mice

Recently, we showed that a methanol extract of Ganoderma lucidum inhibits scratching, an itch-related response, induced by intradermal injections of some pruritogens in mice. The present study investigated whether G.

Cognition & nervesSkin & hydration

Medium relevance

Lion's Mane · 2008 · Journal Article · Journal of essential oil research

Characteristic flavor of volatile oil from dried fruiting bodies of Hericium erinaceus (Bull.:Fr.) Pers.

Metadata-grounded summary: This journal article indexes research on Hericium erinaceus in Journal of essential oil research in 2008. MycoData maps the paper to cognition & nerves based on its title, species context, article metadata, and study classification..

Cognition & nerves

Medium relevance

Reishi · 2008 · Journal Article · Bioscience, Biotechnology, and Biochemistry

Effects of the Antlered Form of Ganoderma lucidum on Tumor Growth and Metastasis in Cyclophosphamide-Treated Mice

We examined the alleviation of cyclophosphamide-induced immunodepression by the antlered form of Ganoderma lucidum (G. lucidum AF) and also evaluated the anti-tumor and anti-metastatic effects of G.

OncologyImmune supportCognition & nervesMetabolic health

Medium relevance

Reishi · 2008 · Journal Article · Nippon Eiyo Shokuryo Gakkaishi

Protective Effects of a Water-soluble Extract from Culture Medium of Ganoderma lucidum Mycelia against Neuronal Damage after Cerebral Ischemia/Reperfusion in Diabetic Rats

Metadata-grounded summary: This journal article indexes research on Ganoderma lucidum in Nippon Eiyo Shokuryo Gakkaishi in 2008. MycoData maps the paper to cognition & nerves, metabolic health based on its title, species context, article metadata, and study classification..

Cognition & nervesMetabolic health

Medium relevance

Reishi · 2008 · Journal Article · Japanese Journal of Complementary and Alternative Medicine

Protective Effects of a Water-Soluble Extract from Culture Medium of Ganoderma lucidum Mycelia against Neuronal Damage after Hypoxia-Ischemia in Mice

Metadata-grounded summary: This journal article indexes research on Ganoderma lucidum in Japanese Journal of Complementary and Alternative Medicine in 2008. MycoData maps the paper to cognition & nerves based on its title, species context, article metadata, and study classification..

Cognition & nerves

Medium relevance

Shiitake · 2007 · Journal Article · Bioscience, Biotechnology, and Biochemistry

Sequence Analysis and Expression of a Blue-Light Photoreceptor Gene, Le.phrA from the Basidiomycetous Mushroom Lentinula edodes

We cloned and sequenced a photoreceptor gene (Le.phrA) from the basidiomycete Lentinula edodes. The product of Le.phrA, Le.PHRA (924 aa residues) contained a serine-rich region, an LOV domain and two PAS domains..

Cognition & nerves

Medium relevance

Reishi · 2006 · Journal Article · Bioscience, Biotechnology, and Biochemistry

Anti-Tumor Activities of the Antlered Form of Ganoderma lucidum in Allogeneic and Syngeneic Tumor-Bearing Mice

We investigated the anti-tumor effects of a dry powder preparation of the antlered form of Ganoderma lucidum (G. lucidum AF, rokkaku-reishi in Japanese), a variant type of G.

OncologyImmune supportCognition & nerves

Medium relevance

Almond Mushroom · 2026 · Preprint · journal metadata

Clinical Predictors, Antibiogram, and the Relationship Between Abnormal Leucocytes and Positive Cerebrospinal Bacterial Isolates in Children seen at a Tertiary Facility in Nigeria.

Abstract Background: Acute bacterial meningitis (ABM) remains a significant public health concern in resource-limited settings like Nigeria. It is a frequent neurologic emergency among children and often presents at under-resourced medical centers..

Cognition & nerves

Medium relevance

Lion's Mane · 2026 · Review · Molecules (Basel, Switzerland)

Recent Advances in Erinacine A: Preparation, Biological Activities, and Biosynthetic Pathway.

Erinacine A, a cyathane diterpenoid derived from the medicinal and edible fungus Hericium erinaceus, is increasingly recognized for its potent neurotrophic and neuroprotective properties..

OncologyImmune supportCognition & nerves

Medium relevance

Almond Mushroom · 2026 · Preprint · journal metadata

Spatial Agent-Based Modeling and Interpretable Machine Learning Predict Combination Therapy Response in HER2-Heterogeneous Breast Cancer

HER2 heterogeneity and reversible phenotypic plasticity play a central role in breast cancer progression and therapeutic resistance, yet how their interaction shapes treatment response remains poorly understood..

OncologyCognition & nerves

Medium relevance

Reishi · 2026 · Review · Nutrients

The Potential of Plant-Derived Foods to Treat Glaucoma: A Review.

Glaucoma, characterized by progressive retinal ganglion cell degeneration and optic nerve damage, is the leading cause of irreversible blindness worldwide. Multiple risk factors influence the pathogenesis and progression of glaucoma..

Immune supportCognition & nerves

Medium relevance

Snow Fungus · 2025 · Review · Fa yi xue za zhi

Forensic Research Progress on Bongkrekic Acid Poisoning.

Bongkrekic acid (BA) is a toxin with stable properties and no distinctive smell. It exists in common foods such as fermented edible grain products, potato products, spoiled tremella fuciformis and auricularia polytricha, as well as auricularia polytricha that has been soaked too long..

Cognition & nervesLiver support

Medium relevance

Almond Mushroom · 2025 · Preprint · medRxiv: the preprint server for health sciences

Identifying and Forecasting Importation and Asymptomatic Spreaders of Multi-drug Resistant Organisms in Hospital Settings.

Healthcare-associated infections (HAIs) from multi-drug resistant organisms (MDROs) pose a significant challenge for healthcare systems. Patients can arrive at hospitals already infected ("importation") or acquire infections during their stay ("nosocomial infection")..

Cognition & nerves

Medium relevance

Maitake · 2025 · Review · Journal of fungi (Basel, Switzerland)

Immunoregulation in Fungal Infections: A Review and Update on the Critical Role of Myeloid-Derived Suppressor Cells.

Myeloid-derived suppressor cells (MDSCs) are a heterogeneous group of immune cells that play a central role in regulating host immune responses during fungal infections..

Immune supportCognition & nervesEnergy & fatigue

Medium relevance