MycoData

OncologyImmune supportCognition & nervesGut & microbiome

Lion's Mane · 2026 · Journal Article · Computational biology and chemistry

Modulation of ABCB1 by Erinacerin S: Binding dynamics and transmembrane helix remodeling.

Erinacerins are a group of bioactive heterocyclic organic compounds known as Isoindolin-1-one metabolites with the molecular formula C8H9N, derived from the mycelia or fruiting bodies of the mushroom Hericium erinaceus. They are known for their neuroprotective, anti-inflammatory, and anticancer properties..

Yellow Morel · 2026 · Journal Article · Journal of virological methods

Prevalence and ribavirin-mediated elimination of Morchella importuna endornavirus 1 (MiEV1) in cultivated Morchella species in China.

Fungal viruses compromise the cultivation of Morchella. We surveyed five mycoviruses (Morchella importuna endornavirus 1 [MiEV1], Morchella importuna endornavirus 2 [MiEV2], Morchella importuna endornavirus 3 [MiEV3], Morchella esculenta fusarivirus 1 [MeFV1], and Morchella esculenta fusarivirus 2 [MeFV2]) in 24….

Respiratory

Turkey Tail · 2025 · Research Article · Polymers

Artificial Neural Network Prediction of Mechanical Properties in Mycelium-Based Biocomposites.

Mycelium-based biocomposites (MBBs) represent a sustainable alternative to synthetic composites, as they are produced from lignocellulosic substrates bonded by fungal mycelium..

Shiitake · 2025 · Research Article · Frontiers in plant science

Effects and formula optimization of Rosa roxbunghii pomace substrate on the yield and volatile flavor compounds of Lentinulaedodes.

INTRODUCTION: Rosa roxbunghii pomace (RRP), a by-product of R. roxbunghii processing, remains largely underutilized.

Turkey Tail · 2025 · Journal Article · Industrial crops and products

Fungal specificity in degradation of Moso bamboo: White-rot versus brown-rot fungi

Moso bamboo (Phyllostachys edulis) is a cornerstone material in industrial processing, bamboo construction, and the manufacturing of bamboo products. However, its unique composition, particularly its high starch content, makes it highly susceptible to fungal decay, which leads to a significant loss of its mechanical….

Reishi · 2025 · Journal Article · Pakistan journal of biological sciences: PJBS

Laccase Characterization from Ganoderma lucidum Grown in Pineapple and Coffee Waste Substrates under Solid Fermentation.

Background and Objective: Laccase as a ligninolytic enzyme has been known for its green-catalysis mechanism, which has the potential to be applied to food industries..

Immune supportMetabolic health

Reishi · 2025 · Journal Article · Food Chemistry: X

Metabolomics-based analysis of changes in functional constituents and activities of Tartary buckwheat by solid-state fermentation with three kinds of edible-medicinal fungi

Solid-state fermentation of Tartary buckwheat using Auricularia auricula, Ganoderma lucidum, and Hericium erinaceus enhanced its functional components, increasing levels of phenols, polysaccharides, proteins, and amino acids, alongside improved antioxidant activity..

Cordyceps · 2025 · Research Article · Virology journal

Molecular characterization of four novel mycoviruses in entomopathogenic and nematophagous fungi.

BACKGROUND: Research on fungal viruses has predominantly focused on phytopathogenic fungi, with some studies elucidating their roles in modulating fungal virulence and influencing plant-fungus interactions..

Respiratory

Cognition & nervesMetabolic health

Lion's Mane · 2025 · Research Article · Molecules (Basel, Switzerland)

Polysorbate 80 Differentially Impacts Erinacine Production Profiles in Submerged Cultures of Hericium.

The mycelia of Hericium erinaceus contain neuroprotective cyathane diterpenoids (e.g., erinacine A). There is evidence that cultivation of submerged mycelia with surfactants increases glucose uptake and biomass, but the impact on erinacine production is unknown..

Reishi · 2025 · Journal Article · World J Microbiol Biotechnol

Preparation of fungal biocomposite for environment friendly packaging of plant saplings

Plastic packaging poses significant environmental and health risks due to its non-degradability and its accumulation as microplastics in soil, plants, and food chains. Fungal biocomposites derived from lignocellulosic biomass offer a sustainable alternative for biodegradable packaging..

Reishi · 2025 · Journal Article · World journal of microbiology & biotechnology

Preparation of fungal biocomposite for environment friendly packaging of plant saplings.

Immune supportGut & microbiomeLiver supportSkin & hydration

Reishi · 2025 · Research Article · Pharmaceuticals (Basel, Switzerland)

Safety Considerations for Natural Products with Adaptogenic and Immunomodulating Activities.

Background/Objectives: Natural products with claimed adaptogenic and/or immunomodulatory effects are widely used in traditional medicine systems across Eurasia. These include herbal remedies (e.g., Panax ginseng), fungi (e.g., Ganoderma lucidum), and animal-derived substances (e.g., propolis from Apis mellifera)..

Reishi · 2025 · Research Article · Biomimetics (Basel, Switzerland)

The Effects of the Substrate Length and Cultivation Time on the Physical and Mechanical Properties of Mycelium-Based Cushioning Materials from Salix psammophila and Peanut Straw.

Mycelium-based biocomposites represent a novel class of environmentally friendly materials. This study investigated the potential of using Salix psammophila and peanut straw as substrates for cultivating Pleurotus ostreatus and Ganoderma lucidum, respectively, to fabricate mycelium-based cushioning materials..

Energy & fatigueGut & microbiomeLiver supportSkin & hydration

Shiitake · 2024 · Research Article · American journal of physiology. Gastrointestinal and liver physiology

AHCC inhibited hepatic stellate cells activation by regulation of cytoglobin induction via TLR2-SAPK/JNK pathway and collagen production via TLR4-NF-κβ pathway.

Cirrhosis, which represents the end stage of liver fibrosis, remains a life-threatening condition without effective treatment. Therefore, prevention of the progression of liver fibrosis through lifestyle habits such as diet and exercise is crucial..

Reishi · 2024 · Journal Article · Plant foods for human nutrition (Dordrecht, Netherlands)

Bidirectional Solid-State Fermentation of Highland Barley by Edible Fungi to Improve Its Functional Components, Antioxidant Activity and Texture Characteristics.

In food industry, the characteristics of food substrate could be improved through its bidirectional solid-state fermentation (BSF) by fungi, because the functional components were produced during BSF..

Snow Fungus · 2024 · Research Article · Applied microbiology and biotechnology

Comprehensive investigations of 2-phenylethanol production by the filamentous fungus Annulohypoxylon stygium.

2-Phenylethanol (2-PE) is an aromatic compound with a rose-like fragrance that is widely used in food and other industries. Yeasts have been implicated in the biosynthesis of 2-PE; however, few studies have reported the involvement of filamentous fungi..

Turkey Tail · 2024 · Journal Article · Journal of food composition and analysis

Determination of the total phenolic content in Hardaliye by amperometric laccase-based biosensor and comparison of the LC-MS/MS

In this study, a laccase-based amperometric biosensor was fabricated for the quantitative analysis of total phenolic content in Hardaliye. The biosensor was constructed using a carbon paste electrode with simple modifications..

Immune supportSkin & hydration

Shiitake · 2024 · Research Article · Foods (Basel, Switzerland)

Effect of Frying Temperatures and Times on the Quality and Flavors of Three Varieties of Lentinus edodes.

The effects of frying times (1, 2, 3, and 4 min) and temperatures (140, 160, 180, and 200 °C) were investigated on the nutritional components, color, texture, and volatile compounds of three Lentinula edodes varieties (808, 0912, and LM) from Guizhou, China..

Energy & fatigueMetabolic healthGut & microbiome

Oyster Mushroom · 2024 · Journal Article · Animal feed science and technology

Effect of mushroom crop residue on growth performance, carcass traits, nutrient digestibility, nitrogen balance, ingestive behavior, ruminal and blood parameters of lambs

Using agricultural wastes as substrates of mushroom cultivation can minimize environmental pollution and provide a high-quality substrate that might be used for animal feeding after cultivation, which is beneficial for ruminants..

Reishi · 2024 · Research Article · Mycobiology

Effects of Environmental and Nutritional Conditions on Mycelium Growth of Three Basidiomycota.

In recent decades, an enormous potential of fungal-based products with characteristics equal to, or even outperforming, classic petroleum-derived products has been acknowledged. The production of these new materials uses mycelium, a root-like structure of fungi consisting of a mass of branching, thread-like hyphae..

Oyster Mushroom · 2024 · Journal Article · Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire

Evaluation of carrot and agroindustrial residues for obtaining Tenebrio molitor (yellow mealworm) powder enriched in bioaccessible provitamin A and colourless carotenoids

In this pilot study Tenebrio molitor larvae were fed with two residues (olive leaf meal and spent Pleurotus ostreatus substrate meal) and wheat flour (control). Carrot was used to provide a source of water and carotenoids..

Immune supportEnergy & fatigueGut & microbiomeSkin & hydration

Reishi · 2024 · Research Article · Bioresources and bioprocessing

Evaluation of cosmetic efficacy of lychee seed fermentation liquid.

BACKGROUND: Lychee seeds were fermented by three kinds of bacteria (Lactobacillus plantarum, Saccharomyces cerevillus and ganoderma lucidum mycelium), and two effective strains were selected by two indexes of activity content and antioxidant, so as to further verify whether lychee seeds have waste multiplication….

Turkey Tail · 2024 · Journal Article · Heliyon

Fungal enzyme degradation of lignin-PLA composites: Insights from experiments and molecular docking simulations

Fungal enzymes are effective in degrading various polymeric materials. In this study, we assessed the initial degradation of composites consisting of lignin-poly(lactic acid) (PLA) with both unmodified lignin (LIG) and oxypropylated lignin (oLIG) incorporated at 10 % and 40 % weight within the PLA matrix in a fungal….

Turkey Tail · 2024 · Research Article · Heliyon

Fungal enzyme degradation of lignin-PLA composites: Insights from experiments and molecular docking simulations.

Oyster Mushroom · 2024 · Journal Article · Food chemistry

In vitro digestibility and angiotensin converting enzyme (ACE) inhibitory activity of solid-state fermented fava beans (Vicia faba L.).

Reducing the content of quickly absorbed carbohydrates and saturated fats in snack formulations while increasing the consumption of high-quality proteins are effective strategies to prevent obesity in childhood..

Immune supportEnergy & fatigueSkin & hydration

Lion's Mane · 2024 · Research Article · Foods (Basel, Switzerland)

Mitigating Oxidative Stress and Promoting Cellular Longevity with Mushroom Extracts.

Oxidative stress can disrupt the body's ability to fight harmful free radicals, leading to premature aging and various health complications. This study investigated the antioxidant and anti-aging properties of four medicinal and edible mushrooms: Ganoderma lucidum, Hericium erinaceus, Pleurotus ostreatus, and Agaricus….

Turkey Tail · 2024 · Research Article · International journal of molecular sciences

Ultra-Pressurized Deposition of Hydrophobic Chitosan Surface Coating on Wood for Fungal Resistance.

Fungi (Neolentinus lepideus, Nl, and Trametes versicolor, Tv) impart wood rot, leading to economic and environmental issues. To overcome this issue, toxic chemicals are commonly employed for wood preservation, impacting the environment and human health..

Reishi · 2024 · Research Article · Current research in food science

Understanding the characteristic changes of retrogradation behavior and edible quality of brown rice modified with inhibiting retrogradation enzymes of Ganoderma lucidum.

Brown rice (BR) has gradually become a new choice for consumers due to its exceptionally nutritional value. Whereas starch retrogradation profoundly reduces its edibility, shelf-life and consumer acceptance, limiting the development of BR and even other starch-based food products..

Cognition & nerves

Oyster Mushroom · 2024 · Journal Article · World J Microbiol Biotechnol

Utilization of local agro-industrial by-products based substrates to enhance production and dietary value of mushroom (P. ostreatus) in Ethiopia

Food insecurity and malnutrition are serious problems in many developing countries, including Ethiopia. This situation warrants an urgent need for the diversification of food sources with enhanced productivity..

Oyster Mushroom · 2024 · Research Article · World journal of microbiology & biotechnology

Utilization of local agro-industrial by-products based substrates to enhance production and dietary value of mushroom (P. ostreatus) in Ethiopia.

Almond Mushroom · 2023 · English Abstract · Revue medicale suisse

[Understanding health equity through artificial intelligence The case of Agent-Based Modelling (ABM)].

Agent-Based Modelling (ABM) is a computer modelling technique that simulates the behaviour and interactions of autonomous agents within a virtual environment. Applied to health equity, this technique allows for a better understanding of the complex social and economic determinants that contribute to health inequities….

Almond Mushroom · 2023 · Clinical Trial Protocol · Contemporary clinical trials

Combining antidepressants and attention bias modification in primary health care (DEPTREAT): Protocol for a pragmatic randomized controlled trial.

BACKGROUND: Major depressive disorder (MDD) is a highly prevalent psychiatric condition associated with significant disability, mortality and economic burden. A large proportion of MDD patients are treated in primary health care in the local community..

Cognition & nerves

Reishi · 2023 · Research Support, Non U.S. Gov'T · Fungal genetics and biology: FG & B

Comparative proteomic analysis of two divergent strains provides insights into thermotolerance mechanisms of Ganoderma lingzhi.

Heat stress (HS) is a major abiotic factor influencing fungal growth and metabolism. However, the genetic basis of thermotolerance in Ganoderma lingzhi (G.

Cordyceps · 2023 · Research Support, Non U.S. Gov'T · Journal of invertebrate pathology

Diversity of anamorphic Cordyceps (formerly Isaria) isolated from Brazilian agricultural sites.

A total of 53 anamorphic strains of Brazilian Cordyceps species currently maintained in a government-owned culture collection, were reassessed for diversity and species identity using multi-loci-based phylogenetic methods..

Enoki · 2023 · Research Support, Non U.S. Gov'T · Food research international (Ottawa, Ont.)

Efficacy of combined caprylic acid and thymol treatments for inactivation of Listeria monocytogenes on enoki mushrooms in household and food-service establishments.

Raw enoki mushroom is a high-risk vector for listeriosis, which led to foodborne outbreaks resulting in four deaths in the United States in 2020. This study aimed to investigate the washing method for the inactivation of L.

Immune supportEnergy & fatigueLiver supportRespiratory

Reishi · 2023 · Research Support, Non U.S. Gov'T · Scientific reports

Immuno-physiological effects of dietary reishi mushroom powder as a source of beta-glucan on Rohu, Labeo rohita challenged with Aeromonas veronii.

Beta-glucans have immense potential to stimulate immune modulation in fish by being injected intramuscularly, supplemented with feed or immersion routes of administration. We studied how supplementing Labeo rohita's diet with reishi mushroom powder containing beta-glucan influenced immunological function..

Almond Mushroom · 2023 · Clinical Trial, Veterinary · International journal for parasitology

Monepantel-based anthelmintic combinations to optimize parasite control in cattle.

Improvement in the use of existing anthelmintics is a high priority need for the pharmaco-parasitology research field, considering the magnitude and severity of anthelmintic resistance as an important issue in livestock production..

Cordyceps · 2023 · Case Reports · ACG case reports journal

Traditional Chinese Medicine, Cordyceps, Related to Hepatoportal Sclerosis.

We describe a case of hepatoportal sclerosis (HPS) identified in an 81-year-old woman taking a traditional Chinese herbal supplementation, Cordyceps. The patient presented with splenomegaly and weight loss..

Liver support

Energy & fatigueMetabolic health

Cordyceps · 2023 · Research Support, Non U.S. Gov'T · Scientific reports

Transcriptome and metabonomics combined analysis revealed the energy supply mechanism involved in fruiting body initiation in Chinese cordyceps.

Chinese cordyceps was one of most valuable traditional Chinese medicine fungi. To elucidate the molecular mechanisms related to energy supply mechanism involved in the initiation and formation of primordium in Chinese cordyceps, we performed the integrated metabolomic and transcriptomic analyses of it at….

Shiitake · 2022 · Case Reports · Internal medicine (Tokyo, Japan)

Bowel Obstruction due to Shiitake Mushrooms: Diagnostic Features on Computed Tomography.

Shiitake mushrooms are edible mushrooms popular in East Asian cuisine. We herein report a 69-year-old man with abdominal distension and vomiting after ingesting several pieces of sautéed Shiitake mushrooms..

Maitake · 2022 · Brief Report · BMC research notes

CD3Ɛ immune restorative ability induced by Maitake Pro4x in immunosupressed BALBc mice.

OBJECTIVES: The aim of this research was to determine if the rich beta glucan compound called Maitake Pro4X can recover the T cell/NK population depleted by Dexamethasone treatment in lymph nodes from cancer-free BALBc female mice..

OncologyImmune support

Immune supportCognition & nervesEnergy & fatigue

Nameko · 2022 · Research Support, Non U.S. Gov'T · Journal of food biochemistry

Chemical properties and anti-fatigue effect of polysaccharide from Pholiota nameko.

The aim of this study was to explore the primary chemical properties and anti-fatigue effect in vivo of Pholiota nameko polysaccharide (PNP). Through UV-visible spectrum, the absorption peaks of proteins, nucleic acids and pigments were not found..

Energy & fatigueMetabolic healthGut & microbiomeLiver support

Cordyceps · 2022 · Research Support, Non U.S. Gov'T · Scientific reports

Cordyceps inhibits ceramide biosynthesis and improves insulin resistance and hepatic steatosis.

Ectopic ceramide accumulation in insulin-responsive tissues contributes to the development of obesity and impairs insulin sensitivity. Moreover, pharmacological inhibition of serine palmitoyl transferase (SPT), the first enzyme essential for ceramide biosynthesis using myriocin in rodents reduces body weight and….

Almond Mushroom · 2022 · Clinical Trial · American journal of clinical oncology

Hematologic Toxicity Comparison of Intensity Modulated Proton Therapy and Intensity Modulated Radiation Therapy in Anal Cancer Patients.

PURPOSE: We hypothesize that hematologic toxicity will be lower in anal cancer patients treated definitively with intensity modulated proton therapy (IMPT) compared with patients treated with intensity modulated radiation therapy (IMRT)..

Oncology

Cordyceps · 2022 · Research Support, Non U.S. Gov'T · Proceedings. Biological sciences

Profiling, monitoring and conserving caterpillar fungus in the Himalayan region using anchored hybrid enrichment markers.

The collection of caterpillar fungus accounts for 50-70% of the household income of thousands of Himalayan communities and has an estimated market value of $5-11 billion across Asia..

Shiitake · 2022 · Comparative Study · Journal of the science of food and agriculture

Role of thermal and non-thermal drying techniques on drying kinetics and the physicochemical properties of shiitake mushroom.

BACKGROUND: Fresh shiitake mushrooms are rich in nutrients, but have high water content, a fast metabolism after harvest, and deteriorate extremely easily. Therefore, the drying of shiitake mushrooms has become a research direction..

Immune support

Cordyceps · 2022 · Research Support, Non U.S. Gov'T · Microbiology spectrum

Species Diversity of Cordyceps-Like Fungi in the Tiankeng Karst Region of China.

Tiankeng acts as a refugium for biodiversity amid a changing global climate, and a previous study has shown that some ancient (Alsophila spinulosa) and unique plants (cool-adapted plants) are present in Tiankeng. However, there are few reports on Ascomycota from the Tiankeng karst region..

Nameko · 2022 · Research Support, Non U.S. Gov'T · Journal of food biochemistry

Structure characterization and antioxidant activity of carboxymethylated polysaccharide from Pholiota nameko.

The objective of this paper was to prepare the carboxymethyl polysaccharide of Pholiota nameko (CPPN) and further evaluate its structural characteristics, water solubility, and antioxidant activities..

Immune support