MycoData

OncologyImmune supportCognition & nervesEnergy & fatigue

Reishi · 2024 · Journal Article · Frontiers in nutrition

UPLC-ESI-MS/MS-based widely targeted metabolomics reveals differences in metabolite composition among four Ganoderma species.

The Chinese name "Lingzhi" refers to Ganoderma genus, which are increasingly used in the food and medical industries. Ganoderma species are often used interchangeably since the differences in their composition are not known..

Almond Mushroom · 2022 · Review · Memory (Hove, England)

Towards a better integration of emotional factors in autobiographical memory.

While the role of emotion in autobiographical memory (ABM) is acknowledged in some models, its specific effects are blurred by narrow approaches towards emotion that are often limited to a distinction between intensity and valence..

Immune supportCognition & nervesRespiratory

Almond Mushroom · 2021 · Review · AIDS research and therapy

New-onset focal seizure as a presenting feature of HIV infection: a case report and mini review to the challenge in resource-limited settings.

BACKGROUND: The frequency of new-onset HIV-associated seizure in the HIV-infected patient is estimated to be between 2 and 11%. Identifying the underlying etiology of new-onset seizure will have a vital impact on the mortality and morbidity of patients living with HIV infection..

Cognition & nervesMetabolic health

Almond Mushroom · 2021 · Review · Acta neurologica Taiwanica

The Clinical Characteristics and Therapeutic Outcomes of Escherichia Coli Meningitis in Adults.

BACKGROUND: To examine the clinical characteristics and therapeutic outcome of Escherichia (E.) coli adult bacterial meningitis (ABM). METHODS: The demographic data, clinical and laboratory features and therapeutic outcome of 25 E.

Almond Mushroom · 2021 · Review · Biological psychology

The ERN as a neural index of changes in performance monitoring following attention training in pediatric obsessive-compulsive disorder.

Evidence of associations between obsessive compulsive disorder (OCD) and alterations in neural indices of performance monitoring, i.e., elevated neural activity following errors, have accelerated interest in the error-related negativity (ERN) as a biomarker for pediatric OCD..

Almond Mushroom · 2021 · Review · Frontiers in veterinary science

The Use of the General Animal-Based Measures Codified Terms in the Scientific Literature on Farm Animal Welfare.

Background: The approach to farm animal welfare evaluation has changed and animal-based measures (ABM), defined as the responses of an animal or effects on an animal, were introduced to assess animal welfare. Animal-based measures can be taken directly on the animal or indirectly and include the use of animal records..

Immune supportCognition & nervesGut & microbiome

Cordyceps · 2025 · Research Support, Non U.S. Gov'T · Molecular nutrition & food research

Edible and Medicinal Fungi as Candidate Natural Antidepressants: Mechanisms and Nutritional Implications.

This systematic review examines the antidepressant potential of edible medicinal fungi (EMFs), focusing on their bioactive compounds and mechanisms of action. EMFs modulate neurotransmitter systems, including serotonin (5-HT) and dopamine (DA), alleviating depressive symptoms..

Cognition & nervesEnergy & fatigueSkin & hydration

Shiitake · 2024 · Research Support, Non U.S. Gov'T · Brain research

Potential role of ergothioneine rich mushroom as anti-aging candidate through elimination of neuronal senescent cells.

Oxidative stress can upset the antioxidant balance and cause accelerated aging including neurodegenerative diseases and decline in physiological function. Therefore, an antioxidant-rich diet plays a crucial role in healthy aging..

Immune supportCognition & nerves

Chaga · 2023 · Journal Article · Biological & pharmaceutical bulletin

3,4-Dihydroxybenzalacetone Inhibits the Propagation of Hydrogen Peroxide-Induced Oxidative Effect via Secretory Components from SH-SY5Y Cells

The polyphenol derivative 3,4-dihydroxybenzalacetone (DBL) is the primary antioxidative component of the medicinal folk mushroom Chaga (Inonotus obliquus (persoon) Pilat)..

Oyster Mushroom · 2023 · Research Article · Science advances

A carnivorous mushroom paralyzes and kills nematodes via a volatile ketone.

The carnivorous mushroom Pleurotus ostreatus uses an unknown toxin to rapidly paralyze and kill nematode prey upon contact. We report that small lollipop-shaped structures (toxocysts) on fungal hyphae are nematicidal and that a volatile ketone, 3-octanone, is detected in these fragile toxocysts..

Cordyceps · 2023 · Journal Article · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Cordycepin improved neuronal synaptic plasticity through CREB-induced NGF upregulation driven by MG-M2 polarization: a microglia-neuron symphony in AD.

PURPOSE: Microglia-neuron crosstalk is critically involved in synaptic plasticity and degeneration by releasing diverse mediators in Alzheimer's disease (AD). Therefore, determining contributors that modulate the systemic microenvironment is essential..

Cognition & nervesMetabolic healthGut & microbiome

Lion's Mane · 2023 · Research Article · Molecules (Basel, Switzerland)

Deacylated Derivative of Hericenone C Treated by Lipase Shows Enhanced Neuroprotective Properties Compared to Its Parent Compound.

Hericium erinaceus, a mushroom species commonly known as Yamabushitake in Japan, is known to have a stimulatory effect on neurotrophic factors, such as brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF)..

Lion's Mane · 2023 · Journal Article · International journal of medicinal mushrooms

Effects of Dietary Supplementation with In Vitro-Cultivated Arboreal Medicinal Mushrooms on Long-Term Memory and Anxiety-Like Behavior of Male Mice.

Health-promoting effects of medicinal mushrooms have been postulated for centuries in folk medicine in Asia and Europe and are currently being verified by scientific research..

Cognition & nervesGut & microbiome

Oyster Mushroom · 2023 · Research Article · Heliyon

Zinc bioaccessibility in finger millet porridge blended with zinc-dense mushroom.

INTRODUCTION: Zinc deficiency is a common health problem among people who rely heavily on cereal-based foods. Consequently, most people from low-income families, particularly young children in Sub-Saharan Africa, who rely mainly on cereal-based meals, have suffered from Zinc deficiency-related health issues..

Cordyceps · 2022 · Journal Article · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Cordycepin suppresses glutamatergic and GABAergic synaptic transmission through activation of A1 adenosine receptor in rat hippocampal CA1 pyramidal neurons.

Cordycepin (known as 3-deoxyadenosine, CRD), a natural product from the valuable traditional Chinese medicine Cordyceps militaris, has been reported to improve cognitive function and modulate neuroprotective effects on the central nervous system (CNS)..

Immune supportCognition & nerves

Cordyceps · 2021 · Journal Article · Journal of neuroinflammation

Cordycepin confers long-term neuroprotection via inhibiting neutrophil infiltration and neuroinflammation after traumatic brain injury.

BACKGROUND: The secondary injury caused by traumatic brain injury (TBI), especially white matter injury (WMI), is highly sensitive to neuroinflammation, which further leads to unfavored long-term outcomes..

OncologyImmune supportCognition & nervesSkin & hydration

Cordyceps · 2021 · Journal Article · American journal of cancer research

Cordycepin inhibits the proliferation of malignant peripheral nerve sheath tumor cells through the p53/Sp1/tubulin pathway.

Neurofibromatosis type 1 (NF1) is one of the most common hereditary neurocutaneous disorders. In addition to skin pigmentation and cutaneous neurofibroma, some patients developed the plexiform neurofibroma since birth..

Cognition & nervesEnergy & fatigueLiver support

Oyster Mushroom · 2021 · Journal Article · Computers and Electronics in Agriculture

Mushroom spawn quality classification with machine learning

During spawn incubation in mushroom cultivation, spawns can be contaminated by a variety of pests and pathogenic molds, which cause virulent crop damage. Contaminated spawns must be classified and discarded before they are delivered to the fruiting stage..

Shiitake · 2004 · Journal Article · Bioscience, Biotechnology, and Biochemistry

A recQ Gene Homolog from the Basidiomycetous Mushroom Lentinula edodes: Sequence Analysis and Expression

We cloned and sequenced a recQ gene homolog from the basidiomycetous mushroom Lentinula edodes (Le.). This gene, named Le.recQ, was found to have a coding capacity of 945 amino acids (aa) and be interrupted by 11 small introns..

Niu-Chang-Chih · 2004 · Journal Article · Food chemistry

Antioxidant properties of methanolic extracts from two kinds of Antrodia camphorata mycelia.

Metadata-grounded summary: This journal article indexes research on Antrodia camphorata in Food chemistry in 2004. MycoData maps the paper to oncology, cognition & nerves, liver support based on its title, species context, article metadata, and study classification..

Niu-Chang-Chih · 2004 · Journal Article · Transactions of the Meeting in Hokkaido Branch of the Japanese Forest Society

Antrodia camphorata (Japanese name Benikusunokitake) in Basidiomycota

Metadata-grounded summary: This journal article indexes research on Antrodia camphorata in Transactions of the Meeting in Hokkaido Branch of the Japanese Forest Society in 2004. MycoData maps the paper to oncology, cognition & nerves, liver support based on its title, species context, article metadata, and study classification..

Immune supportCognition & nervesEnergy & fatigue

Reishi · 2004 · Journal Article · Journal of Pharmacological Sciences

Polysaccharide Extract Isolated From Ganoderma lucidum Protects Rat Cerebral Cortical Neurons From Hypoxia/Reoxygenation Injury

The effect of polysaccharide extract isolated from Ganoderma lucidum (Gl-PS) on rat cortical neuronal cultures exposed to hypoxia/reoxygenation (H/R) was studied in vitro. Gl-PS (1, 10, 100 microg/ml) increased neuron viability following H/R as measured by the inhibition of MTT reduction..

Lion's Mane · 2002 · Journal Article · Shi yong jun xue bao (Online)

A study on the screening of high-yield formulae of vinegar distillers^ grain and nutritional utilization law for Hericium erinaceus

Metadata-grounded summary: This journal article indexes research on Hericium erinaceus in Shi yong jun xue bao (Online) in 2002. MycoData maps the paper to cognition & nerves based on its title, species context, article metadata, and study classification..

OncologyImmune supportCognition & nerves

Almond Mushroom · 1994 · Journal Article · The Japanese Journal of Pharmacology

Inhibitory Action of a (1→6)-β-D-Glucan-Protein Complex (FIII-2-b) Isolated from Agaricus blazei Murill ("Himematsutake") on Meth A Fibrosarcoma-Bearing Mice and Its Antitumor Mechanism

The effects of F III-2-b (Agaricus blazei Murill polysaccharide) with or without 5-fluorouracil (5-FU) on immune responses were investigated in Meth A tumor-bearing and normal mice. The i.p.

Cognition & nervesMetabolic healthLiver support

Reishi · 1990 · Journal Article · Chemical and Pharmaceutical Bulletin

Cardiovascular Effects of Mycelium Extract of Ganoderma lucidum: Inhibition of Sympathetic Outflow as a Mechanism of Its Hypotensive Action

In an effort to understand the mechanism of cardiovascular actions of Ganoderma lucidum which was cultivated in Korea, the mycelium was isolated for a large-scale culture. Water extract of the mycelia was evaluated for its cardiovascular activity in anesthetized rabbits and rats..

Almond Mushroom · 2023 · Preprint · journal metadata

An agent based model (ABM) to reproduce the boolean logic behaviour of neuronal self organized communities through pulse delay modulation and generation of logic gates

The human brain is arguably the most complex “machine” to ever exist. Its detailed functioning is yet to be fully understood, let alone modeled.

Almond Mushroom · 2023 · Preprint · journal metadata

Review of the Brain Behaviour after Injury and Disease for Its Application in an Agent Based Model (ABM)

The brain being arguably the most complex organ in the human body, its detailed functioning is yet to be fully deciphered, let alone accurately modeled. Nonetheless, the medical community has gathered quite a remarkable amount of studies about the consequences of illnesses and injuries on its development and….

Almond Mushroom · 2026 · Review · Bone

A review of bone fracture healing modelling: from mechanobiological theory to personalized rehabilitation protocols.

Despite standard rehabilitation protocols, many patients still suffer from limited mobility, delayed union, or even non-union. This underscores the need for personalized rehabilitation protocols.

Cognition & nervesEnergy & fatigueLiver support

Almond Mushroom · 2026 · Review · ACS biomaterials science & engineering

A Review on AI-Based Data-Driven Models for Optimization of Nanocarriers as Drug Delivery Systems.

Artificial intelligence (AI), primarily machine learning (ML), has revolutionized as a transformative strategy to accelerate nanomedicine research and optimization. The present review highlights the nanocarrier-integrated AI-based approaches to enhance the performance of drug delivery systems..

Oyster Mushroom · 2026 · Preprint · journal metadata

Comparative Evaluation of YOLOv8 and YOLOv11 Models for Efficient Phenotypic Segmentation of Edible Mushrooms

Digital phenotyping is increasingly recognized as a critical tool for quantitative analysis of fungal morphology, particularly in controlled indoor cultivation systems where large numbers of fruiting bodies must be assessed consistently and non-destructively..

Shiitake · 2026 · Published Erratum · Food research international (Ottawa, Ont.)

Corrigendum to "Based on the umami-transformer machine learning model: Screening of umami peptides from ultrasound-assisted enzymatic hydrolysis of shiitake mushrooms and study on their flavor mechanism" [Food Res. Int. 228 (2026) 118379].

Metadata-grounded summary: This published erratum indexes research on Lentinula edodes in Food research international (Ottawa, Ont.) in 2026. MycoData maps the paper to cognition & nerves based on its title, species context, article metadata, and study classification..

OncologyCognition & nervesEnergy & fatigueRespiratory

Cordyceps · 2026 · Review Article · Neural regeneration research

Modulation of mitochondrial dysfunction: Mechanisms and strategies for the use of natural products to treat stroke.

Modulations of mitochondrial dysfunction, which involve a series of dynamic processes such as mitochondrial biogenesis, mitochondrial fusion and fission, mitochondrial transport, mitochondrial autophagy, mitochondrial apoptosis, and oxidative stress, play an important role in the onset and progression of stroke..

Immune supportCognition & nervesEnergy & fatigue

Lion's Mane · 2026 · Review · International journal of molecular sciences

Natural Molecules for Brain Health and Resilience.

The global rise in cognitive decline and neurodegenerative disorders has intensified the search for safe and accessible strategies to support brain health. In recent years, nutraceuticals have gained considerable attention as potential modulators of neurological function due to their antioxidant, anti-inflammatory,….

Cognition & nervesEnergy & fatigueMetabolic health

Cordyceps · 2026 · Review · Cureus

Synergistic Actions of Natural Compounds for Enhancing Cognitive and Physical Performance: A Narrative Review.

Energy drinks are widely consumed for cognitive and physical enhancement, yet most commercial formulations rely on a narrow mechanism: rapid stimulation from synthetic caffeine combined with artificial sweeteners..

Almond Mushroom · 2025 · Review · Journal of mathematical biology

Advances in surrogate modeling for biological agent-based simulations: trends, challenges, and future prospects.

Agent-based modeling (ABM) is a powerful computational approach for studying complex biological and biomedical systems, yet its widespread use remains limited by significant computational demands..

OncologyImmune supportCognition & nervesLiver support

Niu-Chang-Chih · 2025 · Review · Journal of the Chinese Medical Association: JCMA

Anti-inflammatory and anticancer effects of polysaccharides from Antrodia cinnamomea: A review.

Antrodia cinnamomea ( Ac ), also known as "Niu-Chang-Chih" in Chinese, is a valuable fungus that has been widely used as medicine and food among indigenous people in Taiwan. Ac is rich in polysaccharides ( Ac -PS), making it a promising candidate for adjunctive therapy in cancer and inflammation conditions..

Lion's Mane · 2025 · Preprint · journal metadata

Effects of dietary supplementation with in vitro-cultivated arboreal medicinal mushrooms on stress coping strategies, depressive and anxiety-like behaviour of rats.

Abstract Preclinical studies show that an edible arboreal medicinal mushroom – Hericium erinaceus (HE), is neuroprotective against high corticosterone levels and modulates stress-coping strategies of rodents..

OncologyImmune supportCognition & nervesMetabolic health

Chaga · 2025 · Preprint · journal metadata

Mushroom-Derived Compounds as Inhibitors of Advanced Glycation End-Products

Mushrooms have long been valued not only as food but also for their medicinal properties, especially in Eastern European traditional medicine. Species such as Inonotus obliquus, Fomitopsis officinalis, Piptoporus betulinus and Fomes fomentarius have been used to treat gastrointestinal problems, cancers, respiratory….

Almond Mushroom · 2024 · Abstract · Neuro-oncology

CTNI-11. A PHASE 1 OPEN-LABEL STUDY OF BRAF INHIBITOR ABM-1310 IN PATIENTS (PTS) WITH RECURRENT BRAF V600-MUTATED PRIMARY CNS TUMORS

Metadata-grounded summary: This abstract indexes research on Agaricus blazei in Neuro-oncology in 2024. MycoData maps the paper to oncology, cognition & nerves based on its title, species context, article metadata, and study classification..

Lion's Mane · 2024 · Review · Frontiers in nutrition

Enriching the Mediterranean diet could nourish the brain more effectively.

The increasing prevalence of neurodegenerative disorders represents a challenge to the global health of all nations and populations, particularly with increasing longevity..

Immune supportCognition & nervesEnergy & fatigue

Reishi · 2024 · Preprint · journal metadata

Exopolysaccharides extracted from submerged cultures of Ganoderma lucidumactivate the NLRP3 inflammasome

Abstract Interleucin-1β (IL-1β) is a pivotal cytokine in pro-inflammatory response induction, and it is regarded as protective in various diseases. IL-1β secretion is mainly associated with activation of the inflammasome complex, which generally is tightly regulated, depending on two signals for significant activity..

Immune supportCognition & nervesRespiratory

Cordyceps · 2024 · Review · Frontiers in pharmacology

Geo-authentic Tibetan medicine: a traditional pharmacological resource for promoting human health and wellness.

Traditional Tibetan medicine (TTM) is an ancient healing system that has been practiced for more than 2,000 years and involves the use of various medicinal plants for preventing and treating acute mountain sickness, depression, asthma, etc..

OncologyImmune supportCognition & nervesGut & microbiome

Lion's Mane · 2024 · Review · Journal of ethnopharmacology

The ethnopharmacology, phytochemistry and pharmacology of the genus Hericium.

ETHNOPHARMACOLOGICAL RELEVANCE: Mushrooms in the genus Hericium are used as functional food and traditional medicines for a long history in East Asian countries such as China, India, Japan, and Korea..

Immune supportCognition & nervesMetabolic health

Oyster Mushroom · 2022 · Journal Article · Journal of medicinal food

β-Glucan-Rich Extract of Gray Oyster Mushroom, Pleurotus pulmonarius, Improves Object Recognition Memory and Hippocampus Morphology in Mice Fed a High-Fat Diet.

Obesity may cause behavioral alterations, while maternal obesity can contribute to metabolic disorders in subsequent generations. The effect of β-glucan-rich Pleurotus pulmonarius (βgPp) was investigated on mouse neurobehavior and hippocampus and its offspring's hippocampus development..

Immune supportCognition & nervesMetabolic healthLiver support

Cordyceps · 2020 · Review · Phytotherapy research: PTR

Anti-inflammatory effects of cordycepin: A review.

Cordycepin is the major bioactive component extracted from Cordyceps militaris. In recent years, cordycepin has received increasing attention owing to its multiple pharmacological activities.

Turkey Tail · 2015 · Research Support, Non U.S. Gov'T · Journal of molecular recognition: JMR

Aldehyde PEGylation of laccase from Trametes versicolor in route to increase its stability: effect on enzymatic activity.

Laccase is a multicopper oxidase that catalyzes the oxidation of phenolic compounds. Laccase can be used in bioremediation, beverage (wine, fruit juice, and beer) processing, ascorbic acid determination, sugar beet pectin gelation baking, and as a biosensor..

Niu-Chang-Chih · 2012 · Patent · journal metadata

Cultivation barrel structure for Antrodia camphorata

Metadata-grounded summary: This patent indexes research on Antrodia camphorata in 2012. MycoData maps the paper to oncology, cognition & nerves, liver support based on its title, species context, article metadata, and study classification..

Niu-Chang-Chih · 2012 · Patent · journal metadata

Novel cyclohexenone compounds from antrodia camphorata and application thereof

Niu-Chang-Chih · 2012 · Patent · journal metadata

Tower-type cultivation base structure for rapid cultivating fruiting body of Antrodia camphorata