MycoData

King Oyster · 2017 · Journal Article · Carbohydrate polymers

Anti-hyperlipidemic and antioxidant effects of alkali-extractable mycelia polysaccharides by Pleurotus eryngii var. tuolensis.

In this study, we noted that the Al-MPS from Pleurotus eryngii var. tuolensis provoked pharmacological effects on blood lipid profiles and oxidative stress.

Cognition & nervesMetabolic health

Lion's Mane · 2017 · Journal Article · Journal of natural medicines

Anti-obesity activity of Yamabushitake (Hericium erinaceus) powder in ovariectomized mice, and its potentially active compounds.

Hericium erinaceus (H. erinaceus) improves the symptoms of menopause.

King Oyster · 2017 · Research Article · BMC complementary and alternative medicine

Antihyperlipidaemic and hepatoprotective activities of acidic and enzymatic hydrolysis exopolysaccharides from Pleurotus eryngii SI-04.

BACKGROUND: Hyperlipidaemia is the major risk factor contributing to the development and progression of atherosclerosis, fatty liver and cerebrovascular disease. Pleurotus eryngii (P..

King Oyster · 2017 · Journal Article · International journal of biological macromolecules

Antioxidant and anti-hyperlipidemic effects of mycelia zinc polysaccharides by Pleurotus eryngii var. tuoliensis.

The aims of this work were designed to investigate the hepatoprotective and antioxidant effects of acidic- and alkali-extractable mycelia zinc polysaccharides (AcMZPS, AlMZPS) from Pleurotus eryngii var. tuoliensis on high-fat-high-cholesterol emulsion-induced hyperlipidemic mice..

OncologyImmune supportEnergy & fatigueMetabolic health

Niu-Chang-Chih · 2017 · Journal Article · Environmental toxicology

Antrodia camphorata attenuates cigarette smoke-induced ROS production, DNA damage, apoptosis, and inflammation in vascular smooth muscle cells, and atherosclerosis in ApoE-deficient mice.

Cigarette smoke exposure activates several cellular mechanisms predisposing to atherosclerosis, including oxidative stress, dyslipidemia, and vascular inflammation..

Maitake · 2017 · Journal Article · Bioscience, biotechnology, and biochemistry

CE-MS-based metabolomics reveals the metabolic profile of maitake mushroom (Grifola frondosa) strains with different cultivation characteristics.

Maitake mushroom (Grifola frondosa [Dicks.] Gray) is generally cultured using the sawdust of broadleaf trees. The maitake strain Gf433 has high production efficiency, with high-quality of fruiting bodies even when 30% of the birch sawdust on the basal substrate is replaced with conifer sawdust..

Immune supportCognition & nervesEnergy & fatigueMetabolic health

Cordyceps · 2017 · Research Article · Heliyon

Cordyceps militaris improves the survival of Dahl salt-sensitive hypertensive rats possibly via influences of mitochondria and autophagy functions.

The genus Cordyceps and its specific ingredient, cordycepin, have attracted much attention for multiple health benefits and expectations for lifespan extension. We analyzed whether Cordyceps militaris (CM), which contains large amounts of cordycepin, can extend the survival of Dahl salt-sensitive rats, whose survival….

Energy & fatigueMetabolic health

Cordyceps · 2017 · Research Article · Journal of dietary supplements

Cordyceps militaris Improves Tolerance to High-Intensity Exercise After Acute and Chronic Supplementation.

To determine the effects of a mushroom blend containing Cordyceps militaris on high-intensity exercise after 1 and 3 weeks of supplementation. Twenty-eight individuals (Mean ± standard deviation [SD]; Age = 22.7 ± 4.1 yrs; Height = 175.4 ± 8.7 cm; Weight = 71.6 ± 12.0 kg) participated in this randomized, repeated….

Niu-Chang-Chih · 2017 · Journal Article · Journal of ethnopharmacology

Effects of antrosterol from Antrodia camphorata submerged whole broth on lipid homeostasis, antioxidation, alcohol clearance, and anti-inflammation in livers of chronic-alcohol fed mice.

ETHNOPHARMACOLOGICAL RELEVANCE: Antrodia camphorata is a functional fungus in Taiwan and owns several pharmacological functions. Antrosterol, a bioactive constitute of sterols in edible Antrodia camphorata submerged whole broth, can protect liver from CCl4 damage via enhancing antioxidant and anti-inflammatory….

Reishi · 2017 · Journal Article · International journal of medicinal mushrooms

Effects of Exogenous Salicylic Acid on Ganoderic Acid Biosynthesis and the Expression of Key Genes in the Ganoderic Acid Biosynthesis Pathway in the Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes).

We demonstrate herein that salicylic acid (SA) can enhance ganoderic acid (GA) accumulation in the lingzhi or reishi medicinal mushroom Ganoderma lucidum. Following treatment with different concentrations of SA, the GA content was increased 22.72% to 43.04% compared with the control group..

Metabolic healthLiver support

Shiitake · 2017 · Journal Article · European journal of nutrition

Effects of Lentinula edodes consumption on biochemical, hematologic and oxidative stress parameters in rats receiving high-fat diet.

PURPOSE: Functional foods can prevent/reduce the risks related to obesity. Lentinula edodes is a highly nutritious mushroom rich in protein, vitamins and minerals.

OncologyImmune supportMetabolic healthRespiratory

Cordyceps · 2017 · Journal Article · Applied biochemistry and biotechnology

Functional Analysis of Ribonucleotide Reductase from Cordyceps militaris Expressed in Escherichia coli.

Cordyceps militaris produces cordycepin (3'-deoxyadenosine), which has various activities, including anti-oxidant, anti-tumoral, anti-viral, and anti-inflammatory. Ribonucleotide reductase (RNR) seems to be a candidate to produce cordycepin in C..

Energy & fatigueMetabolic health

Cordyceps · 2017 · Journal Article · Gene

Genome-scale metabolic network of Cordyceps militaris useful for comparative analysis of entomopathogenic fungi.

The first genome-scale metabolic network of Cordyceps militaris (iWV1170) was constructed representing its whole metabolisms, which consisted of 894 metabolites and 1,267 metabolic reactions across five compartments, including the plasma membrane, cytoplasm, mitochondria, peroxisome and extracellular space..

King Oyster · 2017 · Journal Article · Carbohydrate polymers

Hepatoprotection of enzymatic-extractable mycelia zinc polysaccharides by Pleurotus eryngii var. tuoliensis.

The purpose of this work was designed to investigate the hepatoprotective and antioxidant effects of enzymatic-extractable mycelia zinc polysaccharides (En-MZPS) from Pleurotus eryngii var. tuoliensis on the hyperlipidemic mice induced by high-fat-high-cholesterol emulsion (HFHCM)..

Cognition & nervesMetabolic healthLiver support

King Oyster · 2017 · Journal Article · International journal of medicinal mushrooms

In Vitro Antioxidant and In Vivo Hypolipidemic Effects of the King Oyster Culinary-Medicinal Mushroom, Pleurotus eryngii var. ferulae DDL01 (Agaricomycetes), in Rats with High-Fat Diet-Induced Fatty Liver and Hyperlipidemia.

We investigated the effect of the culinary-medicinal mushroom Pleurotus eryngii var. ferulae DDL01 on oxidative damage in the liver and brain and a high-fat/high-cholesterol-induced hyperlipidemic model..

Immune supportMetabolic healthGut & microbiome

King Oyster · 2017 · Journal Article · Food & function

In vivo fermentation of a Pleurotus eryngii polysaccharide and its effects on fecal microbiota composition and immune response.

A novel, homogeneous Pleurotus eryngii polysaccharide (PEP) (molecular weight 426 kDa, purity 91.25 ± 3.14%) which mainly consisted of glucose with β-type glycosidic linkages was used to investigate in vivo fermentation behavior and effects on immune response in mice..

Metabolic healthLiver support

Cordyceps · 2017 · Research Article · Nutrition research and practice

Increased glucose metabolism and alpha-glucosidase inhibition in Cordyceps militaris water extract-treated HepG2 cells.

BACKGROUND/OBJECTIVES: Recent living condition improvements, changes in dietary habits, and reductions in physical activity are contributing to an increase in metabolic syndrome symptoms including diabetes and obesity..

Maitake · 2017 · Journal Article · Carbohydrate polymers

Isolation, purification, structural analysis and immunostimulatory activity of water-soluble polysaccharides from Grifola Frondosa fruiting body.

A new polysaccharide had been successfully isolated from maitake mushroom (Grifola Frondosa)-GFP. HPLC and Monosaccharide analysis showed that the average molecular weight of GFP was 155kDa and it was mainly composed of rhamnose, xylose, mannose, glucose, molar ratio of 1.00: 1.04: 1.11: 6.21..

Enoki · 2017 · Journal Article · Journal of proteomics

iTRAQ-based quantitative proteome revealed metabolic changes of Flammulina velutipes mycelia in response to cold stress.

UNLABELLED: Temperature is one of the pivotal factors influencing mycelium growth and fruit-body formation of Flammulina velutipes. To gain insights into hyphae growth and fruit-body formation events and facilitate the identification of potential stage-specific biomarker candidates, we investigated the proteome….

Cordyceps · 2017 · Research Article · Laboratory animal research

Lipolytic effect of novel extracts from mulberry (Morus alba) leaves fermented with Cordyceps militaris in the primary adipocytes derived from SD rats.

Mulberry (Morus alba) leaves are known to have therapeutic effects on lipid metabolism including lipogenesis, lipolysis and hyperlipidemia. However, novel compounds with strong lipolytic ability among 27 extracts of the mulberry leaves fermented with Cordyceps militaris (EMfCs) have not yet been identified..

Cordyceps · 2017 · Journal Article · Archives of microbiology

Molecular analysis and biochemical characteristics of degenerated strains of Cordyceps militaris.

Cordyceps militaris has commercially been cultivated, but its degenerated subcultures have gradually resulted in the reduced production. In this study, the biological characteristics and DNA change of degenerated strains of C.

Maitake · 2017 · Research Article · Iranian journal of pharmaceutical research: IJPR

Purification, Characterization and Antioxidant Activities of Enzymolysis Polysaccharide from Grifola frondosa.

Our previous study revealed that the antioxidant activity of polysaccharide (coded as FGFP) extracted from Grifola frondosa by enzymolysis treatment was significantly superior than that (coded as GFP) extracted by boiling-water..

OncologyImmune supportMetabolic health

King Oyster · 2017 · Journal Article · Carbohydrate polymers

Safe therapeutics of murine melanoma model using a novel antineoplasic, the partially methylated mannogalactan from Pleurotus eryngii.

A heteropolysaccharide was isolated by cold aqueous extraction from edible mushroom Pleurotus eryngii ("King Oyster") basidiocarps and its biological properties were evaluated. Structural assignments were carried out using mono- and bidimensional NMR spectroscopy, monosaccharide composition, and methylation analyses..

Cordyceps · 2017 · Journal Article · Carbohydrate polymers

Structural elucidation and immunostimulatory activity of polysaccharide isolated by subcritical water extraction from Cordyceps militaris.

Water-soluble polysaccharides were obtained from Cordyceps militaris (C. militaris) (CMP) by subcritical water extraction (SWE).

OncologyImmune supportMetabolic healthLiver support

Cordyceps · 2017 · Journal Article · International journal of biological macromolecules

The preparation of three selenium-containing Cordyceps militaris polysaccharides: Characterization and anti-tumor activities.

In the present work, three fractions of selenized Cordyceps militaris polysaccharides (SeCPS) named SeCPS- I, SeCPS- II and SeCPS- III were isolated and purified by ultra-filtration. Their selenium content were measured as 541.3, 863.7 and 623.3μg/g respectively by a graphite furnace atomic absorption spectroscopy..

Niu-Chang-Chih · 2017 · Journal Article · International journal of biological macromolecules

β-d-glucan from Antrodia Camphorata ameliorates LPS-induced inflammation and ROS production in human hepatocytes.

A water soluble Antrodia Camphorata polysaccharide was composed of β-d-glucan, coded as ACP1. ACP1 was derived from cultured Antrodia Camphorata powder, which was extracted, separated and purified by DEAE-52 column and Sephadex G-100 chromatography..

Maitake · 2016 · Journal Article · Sheng wu gong cheng xue bao = Chinese journal of biotechnology

[Structure and immunomodulatory activity of extracellular polysaccharide from Grifola frondosa].

We aimed at analyzing the structure of extracellular polysaccharide A from Grifola frondosa (EXGFP-A) and testing its immunomodulatory activity. Structural analysis shows that EXGFP-A was a contained α-D-glucoside bond and pyranose ring..

Immune supportEnergy & fatigueMetabolic health

Enoki · 2016 · Journal Article · International journal of medicinal mushrooms

Activity of Extracts from Submerged Cultured Mycelium of Winter Mushroom, Flammulina velutipes (Agaricomycetes), on the Immune System In Vitro.

Extracts from submerged cultured mycelium of two strains of Flammulina velutipes, a popular culinary mushroom, were obtained by ultrasound and tested in vitro to determine their activity in innate immunity (monocytes/ macrophages). In addition, polyclonal antibodies against the extracts were produced..

Metabolic healthGut & microbiome

Lion's Mane · 2016 · Journal Article · Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire

Analogy in selenium enrichment and selenium speciation between selenized yeast Saccharomyces cerevisiae and Hericium erinaceus (lion's mane mushroom)

Human selenium supplementation is vastly dominated by selenized yeasts based products not only due to regulation issues but due to the fact that yeasts convert inorganic selenium into organic forms up to 2000 μg g−1 through a well characterized selenium metabolism..

OncologyImmune supportMetabolic healthGut & microbiome

Lion's Mane · 2016 · Journal Article · International journal of medicinal mushrooms

Anti-Inflammatory Effects of Ethanol Extract of Lion's Mane Medicinal Mushroom, Hericium erinaceus (Agaricomycetes), in Mice with Ulcerative Colitis.

This study investigated the anti-inflammatory activity of ethanol extracts of Hericium erinaceus in the inflammatory bowel disease (IBD) model. Twenty C57BL/6 mice were exposed to 2% (w/v) dextran sulfate sodium (DSS) in their drinking water for 7 d to induce acute intestinal inflammation..

Cordyceps · 2016 · Research Article · Oxidative medicine and cellular longevity

Antidiabetic and Antinephritic Activities of Aqueous Extract of Cordyceps militaris Fruit Body in Diet-Streptozotocin-Induced Diabetic Sprague Dawley Rats.

Cordyceps militaris has long been used as a crude drug and folk tonic food in East Asia. The present study aims to evaluate the antidiabetic and antinephritic effects of the aqueous extract of the Cordyceps militaris fruit body (CM) in diet-streptozotocin- (STZ-) induced diabetic rats..

King Oyster · 2016 · Journal Article · International journal of biological macromolecules

Antioxidant and hepatoprotective activities of intracellular polysaccharide from Pleurotus eryngii SI-04.

In present study, the intracellular polysaccharide (IPS) and its two fractions of IPS-1 and IPS-2 were obtained and purified by DEAE-52 cellulose chromatography from Pleurotus eryngii SI-04 mycelia, and their hepatoprotective effects were also investigated..

Energy & fatigueMetabolic healthGut & microbiome

Oyster Mushroom · 2016 · Journal Article · International journal of medicinal mushrooms

Bioavailability and Digestibility of Nutrients from the Dried Oyster Culinary-Medicinal Mushroom, Pleurotus ostreatus (Agaricomycetes): In Vivo Experiments.

There is a limited number of publications on the bioavailability and digestibility of nutrients contained in macrofungi. The aim of this study was to assess the bioavailability and digestibility of macronutrients using in vivo experiments on laboratory animals..

OncologyImmune supportMetabolic healthGut & microbiome

Yellow Morel · 2016 · Research Article · International journal of molecular sciences

Characteristics and Antitumor Activity of Morchella esculenta Polysaccharide Extracted by Pulsed Electric Field.

Polysaccharides from Morchella esculenta have been proven to be functional and helpful for humans. The purpose of this study was to investigate the chemical structure and anti-proliferating and antitumor activities of a Morchella esculenta polysaccharide (MEP) extracted by pulsed electric field (PEF) in submerged….

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

King Oyster · 2016 · Journal Article · Food chemistry

Characterization, antioxidative and bifidogenic effects of polysaccharides from Pleurotus eryngii after heat treatments.

Polysaccharides were extracted from freeze-dried-, oven-dried- and boiling-treated Pleurotus eryngii (FDPEPS, ODPEPS and BTPEPS). Yield of FDPEPS and its total carbohydrates, total polysaccharides, reducing sugars, phenolics and protein content were higher than ODPEPS and BTPEPS..

OncologyImmune supportMetabolic healthLiver support

King Oyster · 2016 · Journal Article · Carbohydrate polymers

Chemical characterization of Pleurotus eryngii polysaccharide and its tumor-inhibitory effects against human hepatoblastoma HepG-2 cells

This study was designed to investigate the chemical characterization and antitumor effects of Pleurotus eryngii polysaccharides (PEP). The crude PEP was fractionated into two fractions, namely PEP-1 and PEP-2..

OncologyEnergy & fatigueMetabolic healthRespiratory

Chaga · 2016 · Research Article · Heliyon

Continuous intake of the Chaga mushroom (Inonotus obliquus) aqueous extract suppresses cancer progression and maintains body temperature in mice.

AIMS: Cancer is a leading cause of morbidity and mortality worldwide; therefore, effective measures for cancer prevention and treatment are in constant demand. The extracts of Inonotus obliquus (Chaga mushroom) demonstrate potent anti-tumor activities and have been used to treat cancer in several countries; however,….

Immune supportMetabolic healthSkin & hydration

Cordyceps · 2016 · Research Article · PloS one

Cordyceps militaris Treatment Preserves Renal Function in Type 2 Diabetic Nephropathy Mice.

Diabetic nephropathy is derived from long-term effects of high blood glucose on kidney function in type 2 diabetic patients. Several antidiabetic drugs and herbal medications have failed to prevent episodes of DN..

Cognition & nervesMetabolic health

Lion's Mane · 2016 · Research Article · Journal of biomedical science

Erinacine A-enriched Hericium erinaceus mycelium ameliorates Alzheimer's disease-related pathologies in APPswe/PS1dE9 transgenic mice.

BACKGROUND: The fruiting body of Hericium erinaceus has been demonstrated to possess anti-dementia activity in mouse model of Alzheimer's disease and people with mild cognitive impairment. However, the therapeutic potential of Hericium erinaceus mycelia on Alzheimer's disease remains unclear..

Shiitake · 2016 · Research Article · PloS one

Genome Sequence of the Edible Cultivated Mushroom Lentinula edodes (Shiitake) Reveals Insights into Lignocellulose Degradation.

Lentinula edodes, one of the most popular, edible mushroom species with a high content of proteins and polysaccharides as well as unique aroma, is widely cultivated in many Asian countries, especially in China, Japan and Korea. As a white rot fungus with lignocellulose degradation ability, L..

OncologyImmune supportMetabolic health

Maitake · 2016 · Journal Article · International journal of medicinal mushrooms

High-Level Production of Exopolysaccharides by a Cosmic Radiation-Induced Mutant M270 of the Maitake Medicinal Mushroom, Grifola frondosa (Agaricomycetes).

A new Grifola frondosa mutant, M270, was successfully isolated for high production of exopolysaccharides (EPSs) using cosmic radiation-induced mutagenesis. We found that the mutant M270 had a clearer and thicker EPS layer (~10 µm) adhering to mycelia than those of its parent strain 265 after Congo red staining..

King Oyster · 2016 · Journal Article · International journal of biological macromolecules

Hypolipidaemic and hypoglycaemic activities of polysaccharide from Pleurotus eryngii in Kunming mice.

Therapeutic drugs must be developed to treat hyperglycaemia and hyperlipidaemia, which are major risk factors for developing coronary artery diseases and atherosclerosis. Pleurotus eryngii is a well-known food resource with functional properties in China.

Immune supportMetabolic healthGut & microbiomeLiver support

Oyster Mushroom · 2016 · Journal Article · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Oral administration of an aqueous extract from the oyster mushroom Pleurotus ostreatus enhances the immunonutritional recovery of malnourished mice.

Mushroom nutriceutical components have lately attracted interest for developing immunonutritional support. However, there is relatively little information pertaining to the use of mushroom preparations for modulating the metabolic and immunological disorders associated to malnutrition..

Cordyceps · 2016 · Journal Article · International journal of biological macromolecules

Preparation and inhibition on α-d-glucosidase of low molecular weight polysaccharide from Cordyceps militaris.

The structural properties and the inhibition on α-d-glucosidase activity of the low molecular weight (LCMPs-II) obtained from the optimized acid hydrolysis of the Cordyceps militaris polysaccharides (CMPs) were investigated in this paper..

OncologyImmune supportMetabolic health

Chaga · 2016 · Research Article · International journal of molecular sciences

Renal Protective Effects of Low Molecular Weight of Inonotus obliquus Polysaccharide (LIOP) on HFD/STZ-Induced Nephropathy in Mice.

Diabetic nephropathy (DN) is the leading cause of end-stage renal disease in diabetes mellitus. Oxidative stress, insulin resistance and pro-inflammatory cytokines have been shown to play an important role in pathogeneses of renal damage on type 2 diabetes mellitus (DM)..

Cordyceps · 2016 · Journal Article · International journal of biological macromolecules

Synthesis, characterization and antioxidant activity of selenium polysaccharide from Cordyceps militaris.

A purified selenium-containing derivatives of Cordyceps militaris polysaccharide synthesized using H2SeO3/HNO3 and BaCl2 as a catalyst was investigated in this paper. The reaction condition was optimized by selecting different reaction temperature and period..

Immune supportCognition & nervesEnergy & fatigueMetabolic health

Lion's Mane · 2015 · Review · Journal of agricultural and food chemistry

Chemistry, Nutrition, and Health-Promoting Properties of Hericium erinaceus (Lion's Mane) Mushroom Fruiting Bodies and Mycelia and Their Bioactive Compounds.

The culinary and medicinal mushroom Hericium erinaceus is widely consumed in Asian countries, but apparently not in the United States, for its nutritional and health benefits..

OncologyImmune supportCognition & nervesMetabolic health

Lion's Mane · 2014 · Review · Food & function

Hericium erinaceus (Yamabushitake): a unique resource for developing functional foods and medicines.

Hericium erinaceus (HE) is a fungus inhabiting the mountainous areas of the northeast territories in Asia. HE has been used in traditional folk medicine and medicinal cuisine in China, Korea and Japan..