MycoData

Almond Mushroom · 2025 · Preprint · journal metadata

Disrupted endothelial cell–cell dynamics in ALK1 and SMAD4 deficiency drive arteriovenous malformations

Arteriovenous malformations (AVMs) are a hallmark of hereditary haemorrhagic telangiectasia (HHT) and arise from abnormal vascular remodelling. Although AVM formation has been associated with disruptions in the BMP9/10 signalling pathway, the distinct contributions of its components remain unclear..

Almond Mushroom · 2025 · Preprint · journal metadata

Dual Chromatographic Analysis of Pesticide Residues in Eggplants: A Green Approach to Food Safety Monitoring

Abstract The determination of pesticide residues is crucial for safeguarding human health and ensuring food safety, while also contributing to environmental sustainability. Chlorfenapyr (CLF), abamectin (ABM), and fenpyroximate (FNP) are widely employed in eggplant (Solanum melongena L.) cultivation for pest control..

Almond Mushroom · 2025 · Preprint · journal metadata

Evaluating the impact of NPC1 SNPs on entry efficiency of Filovirus in vitro: agent-based model approach

The interaction between the Niemann-Pick C1 (NPC1) protein and the glycoprotein (GP) of filoviruses is essential for viral entry into host cells. Single nucleotide polymorphisms (SNPs) in NPC1, which lead to amino acid substitutions, can significantly alter viral entry efficiency..

Almond Mushroom · 2025 · Preprint · journal metadata

Exploring the relationship between vascular remodelling and tumour growth using agent-based modelling

We develop a multiscale agent-based model (ABM) to investigate the effect that mechanical interactions between proliferating tumour cells and the surrounding vasculature have on the oxygen supply to the tumour microenvironment (TME), the tumour’s growth dynamics, and its response to radiotherapy..

OncologyEnergy & fatigue

Energy & fatigueRespiratory

Almond Mushroom · 2025 · Preprint · journal metadata

Fine-Grained Synthetic Population Generation and Agent-Based Models for COVID-19 in Malta

This study presents the development of a fine-grained COVID-19 agent-based model (Agent-based Model (ABM)) specifically designed for Malta, leveraging a synthetic population that captures the country’s demographic and tourism characteristics. The research is structured into three phases..

Cognition & nervesLiver support

Snow Fungus · 2025 · Review · Fa yi xue za zhi

Forensic Research Progress on Bongkrekic Acid Poisoning.

Bongkrekic acid (BA) is a toxin with stable properties and no distinctive smell. It exists in common foods such as fermented edible grain products, potato products, spoiled tremella fuciformis and auricularia polytricha, as well as auricularia polytricha that has been soaked too long..

Almond Mushroom · 2025 · Preprint · journal metadata

From Intention to Loyalty: Unfolding Tokenized Smart Contract Incentives in Ecotourism via Agent-Based Modeling

Abstract This study investigates how tokenized incentives supported by blockchain-enabled smart contracts can influence eco-tourists’ sustainable behaviors and loyalty..

Enoki · 2025 · Review · Mycology

Fungal graviresponses: Physiological and molecular insights from tissue reorientation in the gravity vector.

Graviresponses, the growth responses of organisms to gravitational alterations, are pivotal yet understudied phenomena in fungi compared to plants and animals. Fungi perceive gravity through proposed statoliths, including nuclei connected to actin filaments, octahedral protein crystals, and floating lipid globules..

Immune supportMetabolic healthGut & microbiome

Reishi · 2025 · Review · Poultry science

Harnessing mushrooms for poultry nutrition: Boosting health, immunity, and productivity.

Edible mushrooms, the fruiting bodies of fungi, are emerging as promising functional feed additives in poultry nutrition, offering a sustainable alternative to synthetic growth promoters..

OncologyImmune supportSkin & hydration

Turkey Tail · 2025 · Review · Foods (Basel, Switzerland)

Himalayan Mushrooms as a Natural Source of Ergosterol and Vitamin D2: A Review of Nutraceutical and Functional Food Perspectives.

Mushroom diversity is essential for maintaining ecological balance and provides valuable bioactive compounds for human use. Beyond their nutritional value, mushrooms contribute to functional foods and have applications in nutraceuticals, pharmaceuticals, and biotechnology..

Immune supportMetabolic healthLiver supportSkin & hydration

Reishi · 2025 · Review · Frontiers in cell and developmental biology

Hydrogels incorporating active compounds from traditional Chinese medicine for diabetic wound healing: mechanistic pathways and bioengineering progress.

Diabetic wounds, especially foot ulcers, pose significant clinical challenges due to persistent inflammation, oxidative stress, impaired angiogenesis, and a high risk of infection. Advanced therapeutic strategies are needed to actively modulate the wound microenvironment..

Almond Mushroom · 2025 · Preprint · medRxiv: the preprint server for health sciences

Identifying and Forecasting Importation and Asymptomatic Spreaders of Multi-drug Resistant Organisms in Hospital Settings.

Healthcare-associated infections (HAIs) from multi-drug resistant organisms (MDROs) pose a significant challenge for healthcare systems. Patients can arrive at hospitals already infected ("importation") or acquire infections during their stay ("nosocomial infection")..

Immune supportCognition & nervesEnergy & fatigue

Maitake · 2025 · Review · Journal of fungi (Basel, Switzerland)

Immunoregulation in Fungal Infections: A Review and Update on the Critical Role of Myeloid-Derived Suppressor Cells.

Myeloid-derived suppressor cells (MDSCs) are a heterogeneous group of immune cells that play a central role in regulating host immune responses during fungal infections..

Almond Mushroom · 2025 · Preprint · journal metadata

Impact of environmental land lease contract specification on implementation of nature inclusive farming

Background: Environmental Land Lease Contracts (ELLCs) are contracts in which farmers receive a discount on their rent upon implementing biodiversity measures. ELLCs gain more and more attention as a tool to help reversing biodiversity loss..

Almond Mushroom · 2025 · Preprint · journal metadata

Impact of initial infected characteristics in an agent-based model of infectious respiratory disease: A methodological study

There is limited existing literature about how infectious conditions are introduced in agent-based models (ABMs). This methodological study investigated the impact of the number, timing, and age of initial infected agents on the development of infectious disease outbreaks in ABMs, using influenza as an example..

Turkey Tail · 2025 · Review · Journal of environmental management

Insights into bioremediation of pharmaceuticals from wastewater streams: A meta-analysis of build type and organism selection.

Pharmaceuticals are widely used to manage health issues, but their release into the environment poses risks to human health and ecosystems, and most wastewater treatment plants are not designed to remove them. The suite of alternative treatments (e.g.

Almond Mushroom · 2025 · Preprint · bioRxiv: the preprint server for biology

Lung architecture amplifies tissue deposition in an agent-based model of fibrotic development.

Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease where excessive extracellular matrix (ECM) deposition and remodeling stiffens the lung, impeding its function..

Cognition & nervesRespiratory

Almond Mushroom · 2025 · Preprint · journal metadata

ML-ABC: Machine-learning assisted Approximate Bayesian Computation for efficient calibration of agent-based models for pandemic outbreak analysis

Abstract Mathematical modelling with agent-based models (ABMs) has gained popularity during the COVID-19 pandemic, but their complexity makes efficient and robust calibration to data challenging, particularly when applying Bayesian methods to quantify parameter uncertainty..

Almond Mushroom · 2025 · Preprint · medRxiv: the preprint server for health sciences

Mobility and non-household environments: understanding dengue transmission patterns in urban contexts.

Households (HH) have been traditionally described as the main environments where people are at risk of dengue and other arbovirus infections. Mounting entomological evidence suggests a larger role for environments other than HH..

Almond Mushroom · 2025 · Preprint · journal metadata

Modeling and Simulating Agent-Based City Migration Using Conway’s Game of Life

Agent-based modeling (ABM) has become a cornerstone of complexity science, enabling the study of heterogeneous agents interacting within dynamic environments. Among ABM frameworks, John Conway’s Game of Life (GoL) stands out for its simplicity and ability to generate emergent macroscopic patterns from basic….

OncologyLiver supportRespiratory

Almond Mushroom · 2025 · Preprint · bioRxiv: the preprint server for biology

Modeling of hepatitis B virus infection spread in primary human hepatocytes.

Chronic hepatitis B virus (HBV) infection poses a significant global health threat, causing severe liver diseases including cirrhosis and hepatocellular carcinoma..

Immune supportEnergy & fatigueGut & microbiome

Reishi · 2025 · Review · Poultry science

Molecular approaches for enhancing fermented bamboo-derived feed additives: A sustainable nutritional innovation for poultry.

The function of fermented and non fermented bamboo-derived feed additives in poultry nutrition is critically assessed in this review, with emphasis on the effects on growth performance, immunity, intestinal health, egg and meat quality..

Reishi · 2025 · Review · Drug design, development and therapy

Molecular Pharmacological Interventions for Endometrial Cancer: A Comprehensive Review.

Endometrial cancer, a common malignancy of the female reproductive system, has a rising incidence and complex clinical management due to its diverse molecular subtypes..

OncologyImmune supportMetabolic healthGut & microbiome

Lion's Mane · 2025 · Review · Foods (Basel, Switzerland)

Mushrooms as Nutritional Powerhouses: A Review of Their Bioactive Compounds, Health Benefits, and Value-Added Products.

Mushrooms are known to be a nutritional powerhouse, offering diverse bioactive compounds that promote and enhance health. Mushrooms provide a distinguishable taste and aroma and are an essential source of vitamin D2, vitamin B complex, hydroxybenzoic acids (HBAs) and hydroxycinnamic acids (HCAs), terpenes, sterols,….

Immune supportSkin & hydration

Reishi · 2025 · Review · Archives of dermatological research

Mushrooms in modern cosmetics: unlocking anti-aging, antioxidant, and therapeutic potential.

Mushrooms have gained significant attention in the cosmetics industry due to their rich bioactive compounds with numerous skin benefits. This review explores the potential of various mushroom species as ingredients in cosmeceuticals, focusing on their anti-aging, anti-wrinkle, skin whitening, moisturizing,….

OncologyImmune supportRespiratory

Almond Mushroom · 2025 · Preprint · bioRxiv: the preprint server for biology

Partially-functional exhausted CD8+ T cells can contribute to short-term viral suppression: a computational prediction for children with perinatal HIV.

We and others have reported evidence of T cell exhaustion in children with perinatal HIV with increased expression of inhibitory receptors PD-1, CD160, and TIM-3, but there is limited data on the virologic functional consequences of this immune exhaustion..

Reishi · 2025 · Review · Frontiers in pharmacology

Plant polysaccharides influence tumor development based on epigenetics: a review.

Plant polysaccharides have emerged as pivotal epigenetic modulators in oncology, offering multi-target therapeutic potential to address toxicity and drug resistance limitations of conventional therapies..

OncologyImmune supportMetabolic health

Lion's Mane · 2025 · Review · Journal of fungi (Basel, Switzerland)

Potential Medicinal Fungi from Freshwater Environments as Resources of Bioactive Compounds.

Owing to their nutritional, culinary, and nutraceutical, mushrooms are worldwide consumed and appreciated. Moreover, many of these mushrooms are also known as medicinal mushrooms since they possess several pharmacological properties attributable to a huge number of bioactive compounds derived from their sporophores..

Almond Mushroom · 2025 · Preprint · journal metadata

Predicting Polarization Using Personality Traits - Calibrating an Agent-Based Model on Survey Data

We examine whether classic opinion-dynamics models can be strengthened by grounding their core parameters in psychological domain knowledge. First, we fielded a preregistered survey experiment in Germany (N = 1,804) that mimics a single ABM updating step..

Reishi · 2025 · Review · Food research international (Ottawa, Ont.)

Radioprotective effect of edible and medicinal mushrooms against ionizing radiation: Components, potential mechanisms, and applications.

Ionizing radiation can cause severe damage to the body. The use of natural products as radioprotective agents has gained increasing popularity and attention in recent years..

Immune supportMetabolic health

Reishi · 2025 · Review · Carbohydrate polymers

Refined regulation of polysaccharide biosynthesis in edible and medicinal fungi: From pathways to production.

Polysaccharides derived from edible and medicinal fungi (EMF) exhibit various biological activities, rendering them useful in the pharmaceutical, nutraceutical, and food industries..

Almond Mushroom · 2025 · Preprint · journal metadata

Reluctance Toward Complex Market Modelling and Simulation in The French Extractive and/or Recycling Sector: A Sociological Perspective on Agent-Based Approach

In France, the extractive and recycling (ExtRec) sector plays a critical role in resource recovery and circular economy transitions; and representing complexity in the modelling and simulation of material and waste flows would allow the sector to better capture the effects of various stakeholders’ decisions on waste….

OncologyImmune supportMetabolic health

Enoki · 2025 · Review · Current issues in molecular biology

Research Progress on Nutritional Components, Functional Active Components, and Pharmacological Properties of Floccularia luteovirens.

Edible and medicinal fungi are a general term for large fungi with both edible and medicinal values. As a unique wild edible and medicinal fungus in the Qinghai-Tibet Plateau, the 'Four Medical Classics' of the Tang Dynasty has recorded Floccularia luteovirens effects of external application and internal….

Almond Mushroom · 2025 · Preprint · journal metadata

RESET (Ready for Safe Cancer Treatment) – a comprehensive tool for improving quality and optimizing perioperative care and safe discharge planning in surgical oncology: study protocol for a large-scale long-term trial including a randomized control group, with elements of exploratory cross-sectional study.

Abstract Background Prolonged hospitalizations and rehospitalizations are common challenges in oncological surgery, often resulting in increased morbidity, increased healthcare costs, and diminished patient outcomes..

Oncology

Almond Mushroom · 2025 · Preprint · bioRxiv: the preprint server for biology

Rethinking the seven-day treatment-free interval in T-cell engager therapy using agent-based modeling.

BACKGROUND: The CD3/CD19 bispecific T cell engager (TCE) blinatumomab has shown efficacy in relapsed/refractory (R/R) B-cell acute lymphoblastic leukemia (B-ALL), but response rates are often limited by T cell exhaustion..

Almond Mushroom · 2025 · Preprint · journal metadata

Simulating The Effect of the Radiotherapy on Cancer Stem Cell Evolution

ABSTRACT Radiotherapy is one of the most effective treatments for cancer. However, the radiation on cancer often leads to further tumor evolution and resistance.

Oncology

OncologyImmune supportEnergy & fatigueMetabolic health

Almond Mushroom · 2025 · Preprint · journal metadata

Spatiotemporal Simulation of Radiotherapy Impact on Stage III Sigmoid Colon Cancer Using a Metabolically Coupled Agent-Based Model

Colorectal cancer (CRC), particularly sigmoid colon adenocarcinoma, presents complex therapeutic challenges at advanced stages. While fractionated radiotherapy combined with chemotherapy and immune involvement is clinically effective, its outcomes vary due to tumor heterogeneity, hypoxia, and treatment-induced….

Almond Mushroom · 2025 · Preprint · journal metadata

Stage 2: The Efficacy of Attentional Bias Modification for Anxiety: A Registered Replication

Generalised anxiety disorder is a prevalent condition linked to the presence of cognitive biases, including attention bias. Attention bias is the tendency to attend preferentially to threat-related stimuli and has been consistently observed in high anxious samples..

Shiitake · 2025 · Preprint · journal metadata

Statistical optimization of fermentation conditions for metabolites production by Lentinus edodes and investigation of anticancer activity

Abstract The investigation was carried out to increase polysaccharide yield utilizing statistical strategies, starting with submerge and shifting to solid-state fermentation, with the main aim of promoting the anticancer properties of Lentinus edodes (shiitake) fruit and exploring the rheological properties of….

Turkey Tail · 2025 · Review · Frontiers in microbiology

Sustainable strategies for hospital wastewater treatment: bioremediation, phytoremediation, and hybrid approaches for emerging pollutants.

Hospital wastewater (HWW) is a complex matrix of pharmaceutical residues, antibiotic resistance genes (ARGs), pathogens, and emerging contaminants that threaten public health and ecosystems..

Reishi · 2025 · Review · Journal of agricultural and food chemistry

Synergies between Carbon Sequestration, Nitrogen Utilization, and Mushroom Quality: A Comprehensive Review of Substrate, Fungi, and Soil Interactions.

Mushroom cultivation offers a sustainable approach by combining carbon sequestration, nitrogen use, and quality food production. This review synthesizes current knowledge on the synergistic interactions between substrate composition, fungal species, environmental factors, and their cumulative effects on the carbon and….

Reishi · 2025 · Review · Nanomaterials (Basel, Switzerland)

Synthesis, Application and Prospects of Carbon Dots as A Medicine Food Homology.

Against the background of the vigorous development of materials science and the deep cross-infiltration in many fields, a new medicine food homology, carbon dots (herein combined and abbreviated as MFH-CDs), has sprung up, showing great potential..

OncologyLiver support

Turkey Tail · 2025 · Review · International journal of molecular sciences

Systematic Evaluation of Biodegradation of Azo Dyes by Microorganisms: Efficient Species, Physicochemical Factors, and Enzymatic Systems.

Modern culture, strongly influenced by the growth of sectors such as the fashion and textile industries, has generated an environmental trend that is difficult to reverse..

Metabolic health

Almond Mushroom · 2025 · Preprint · journal metadata

The Effect of Police Deployment Strategy on Emergency Response Times: An Agent-based Modelling Investigation

Abstract Objectives: This study investigates the impact of three police deployment strategies on emergency response times using agent-based modelling (ABM). Specifically, it evaluates the effectiveness of random patrol, stationary deployment (optimal spreading), and static deployment (idling at last incident….

Almond Mushroom · 2025 · Preprint · journal metadata

The Efficacy of Attentional Bias Modification for Anxiety: A Registered Replication

Almond Mushroom · 2025 · Preprint · journal metadata

The Efficacy of Attentional Bias Modification for Anxiety: A Registered Replication

Almond Mushroom · 2025 · Preprint · journal metadata

The Efficacy of Attentional Bias Modification for Anxiety: A Registered Replication

Reishi · 2025 · Review · 3 Biotech

The role of statistical methods in optimizing and enhancing fungal chitosan commercial production.

UNLABELLED: This review portrays the role of fermentation technology in the production of fungal chitosan (FCH) under optimized conditions using statistical methods..