MycoData

Thirty percent of deaths worldwide are caused by cardiovascular disorders (CVDs). As per the WHO data, the number of fatalities due to CVDs is 17.9 million years, and it is projected to cause 22.2 million deaths by 2030.

Immune supportMetabolic health

Medium relevance

Almond Mushroom · 2025 · Preprint · journal metadata

War, Belief, and the Needle: An Agent-Based Analysis of Vaccine Hesitancy in Ukraine

Abstract Background Vaccine uptake in conflict zones is hindered by disrupted supply chains, instability, and eroded trust, leaving millions unvaccinated. Traditional models overlook behavioral and social dynamics shaping vaccine attitudes..

Medium relevance

Almond Mushroom · 2024 · Preprint · journal metadata

A Hybrid Simulation Model of HIV Program Interventions: From Transmission Behavior to Macroeconomic Impacts

While several studies have examined the public health effects of HIV investments, there is a smaller literature that examines the macroeconomic impacts of such investments. The most recent efforts have utilized econometric analyses of country-level panel data, as well as demographic simulations of HIV spending..

Energy & fatigue

Medium relevance

Oyster Mushroom · 2024 · Review · Materials (Basel, Switzerland)

Advances in the Applications of Clinoptilolite-Rich Tuffs.

Adsorptive, catalytic, and antibacterial properties of clinoptilolite-rich tuffs (ZT) are presented here. ZT transformed into Fe-containing ZT (Fe-ZT) removes various organic and inorganic anions from water.

Medium relevance

Almond Mushroom · 2024 · Preprint · journal metadata

Agent-Based Modeling of Virtual Tumors Reveals the Critical Influence of Microenvironmental Complexity on Immunotherapy Efficacy

Since the introduction of the first immune checkpoint inhibitor (ICI), immunotherapy has changed the landscape of molecular therapeutics for cancers. However, ICIs do not work equally well on all cancers and for all patients..

OncologyImmune support

Medium relevance

Almond Mushroom · 2024 · Preprint · journal metadata

Agent-based modelling of Mycobacterium tuberculosis transmission: A systematic review

Abstract Background: Traditional epidemiological models simplify many aspects of Mycobacterium tuberculosis transmission to capture observed tuberculosis (TB) epidemic dynamics, leading to interest in more advanced methodologies,such as agent-based modelling (ABM), that can more flexibly represent the underlying….

Medium relevance

Almond Mushroom · 2024 · Preprint · journal metadata

An Agent-Based Model for Disease Epidemics in Greece

In this research, we present the first steps taken towards a data-driven agent-based model (ABM) specifically designed for simulating infectious disease dynamics in Greece..

Respiratory

Medium relevance

Almond Mushroom · 2024 · Preprint · journal metadata

An Assessment of Agent-Based Modelling Tools for Community-Based Adaptation to Climate Change

Human induced climate change led to the recognition of Community-Based Adaptation (CBA) as one of the remedies in building adaptive capacity and resilience of communities. It recognizes the agency of communities in shaping the optimal strategy..

Cognition & nerves

Medium relevance

Almond Mushroom · 2024 · Preprint · journal metadata

An Overview of the Utility of Autonomic Balance Measurement in Clinical Practice.

Background: Autonomic balance measurement (ABM) is a valuable tool in clinical practice for assessing the functioning of the autonomic nervous system (ANS), which controls involuntary bodily functions. Here we summarize the current understanding of the utility of autonomic balance measurement in clinical practice..

Cognition & nervesEnergy & fatigueMetabolic health

Medium relevance

Shiitake · 2024 · Review · Current opinion in biotechnology

Anti-inflammatory and immunomodulatory properties of polysaccharides in mushrooms.

Mushrooms are distinguished as important food-containing polysaccharides possessing potent anti-inflammatory and immunomodulating properties. These compounds belong mostly to polysaccharides that are mostly β-D-glucans..

Immune supportMetabolic health

Medium relevance

Lion's Mane · 2024 · Review · Phytomedicine: international journal of phytotherapy and phytopharmacology

Anticancer diterpenes of African natural products: Mechanistic pathways and preclinical developments.

BACKGROUND: The African continent is home to five biodiversity hotspots, boasting an immense wealth of medicinal flora, fungi and marine life. Diterpenes extracted from such natural products have compelling cytotoxic activities that warrant further exploration for the drug market, particularly in cancer therapy, where….

OncologyCognition & nerves

Medium relevance

Almond Mushroom · 2024 · Preprint · journal metadata

Assessing Walkability in Urban Environments: A Comprehensive Overview

Walkability, defined as the degree to which urban environments encourage walking, is a vital component of sustainable urban development. It enhances public health, reduces environmental pollution, and fosters social cohesion..

Medium relevance

Almond Mushroom · 2024 · Preprint · journal metadata

Bone Health in Newly Diagnosed Female Breast Cancer Patients in China: A Cross-sectional Study

Abstract Background and Purpose Bone health problem is one of the important concomitant diseases of breast cancer (BC). This study aimed to investigate the status of bone health of newly diagnosed female BC patients in China..

Oncology

Medium relevance

Almond Mushroom · 2024 · Preprint · journal metadata

D5.3 Agent-based model at the European scale

This document presents the generalised linear model (GLM) and agent-based model (ABM) that were developed in the H2020 project BESTMAP to model and predict the uptake of Agri-Environmental Schemes (AES) in the European Union..

Liver support

Medium relevance

Almond Mushroom · 2024 · Preprint · journal metadata

Dynamic Coalition Formation Among IoT Service Providers: A Systematic Exploration of IoT Dynamics Using an Agent-Based Model

This paper introduces an Agent-Based Model (ABM) for investigating the dynamics of the Internet of Things (IoT) ecosystem, specifically focusing on dynamic coalition formation among IoT Service Providers (SPs)..

Medium relevance

Almond Mushroom · 2024 · Preprint · journal metadata

Estimates of SARS-CoV-2 infections and population immunity after the COVID-19 pandemic in Austria: Analysis of national wastewater data

ABSTRACT Background Post-pandemic surveillance data on COVID-19 infections may help inform future public health policies regarding SARS-CoV-2 testing, vaccinations or other COVID-19 measures..

Immune supportRespiratory

Medium relevance

Almond Mushroom · 2024 · Preprint · journal metadata

Examining The Effects of Carbon Dioxide Emissions on Human Brain Activity Using Agent-Based Modeling

The escalating levels of atmospheric carbon dioxide (CO2) due to anthropogenic activities have raised significant concerns regarding their far-reaching consequences, including potential impacts on human brain function..

Cognition & nerves

Medium relevance

Almond Mushroom · 2024 · Preprint · journal metadata

Exploring the use of environment-agent-based models for risk assessment of Great Lakes piping plovers

The Piping Plover Charadrius melodus is an endangered species of shorebird endemic to North America. This species has been the centre of many modelling studies in the last decade..

Medium relevance

Reishi · 2024 · Review · International journal of medicinal mushrooms

Ganoderic Acid A: A Potential Natural Neuroprotective Agent for Neurological Disorders: A Review.

Ganoderic acid A (GAA) is one of the major triterpenoids in Ganoderma lucidum (GL). Accumulating evidence has indicated that GAA demonstrates multiple pharmacological effects and exhibits treatment potential for various neurological disorders..

OncologyImmune supportCognition & nerves

Medium relevance

Almond Mushroom · 2024 · Preprint · journal metadata

How Effective are Tabletop Role-Playing (Serious) Games in Understanding and Validating the Predictive Capabilities of Disaster Response Agent-based Models?

Tabletop role-playing games (TRPGs) for disaster response management are collaborative exercises in which participants take on the roles of characters and are guided by a “game master.” TRPGs are useful tools for training, improving the preparedness of emergency responders, and understanding/validating agent-based….

Energy & fatigue

Medium relevance

Almond Mushroom · 2024 · Preprint · journal metadata

Identifying Importation and Asymptomatic Spreaders of Multi-drug Resistant Organisms in Hospital Settings

Abstract Healthcare-associated infections (HAIs) due to multi-drug resistant organisms (MDROs) are a significant burden to the healthcare system. Patients are sometimes already infected at the time of admission to the hospital (referred to as “importation”), and additional patients might get infected in the hospital….

Cognition & nervesEnergy & fatigue

Medium relevance

Mesima · 2024 · Review · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Initial report on the multiple biological and pharmacological properties of hispolon: Exploring stochastic mechanisms.

The development of natural substances derived from nature poses a significant challenge as technologies for the extraction and characterization of active principles advance. Hispolon has received a lot of attention in recent years, ascribable to its wide range of biological activities..

OncologyImmune supportEnergy & fatigueMetabolic health

Medium relevance

Reishi · 2024 · Review · Physiology international

Innovative prophylactic and therapeutic approaches in liver cirrhosis.

Liver cirrhosis is the consequence of chronicisation and of the evolution of untreated liver diseases. The complexity of the disease and the complications it can cause have been and are still intensively researched, aiming to discover new therapies or improve existing ones for the effective management of liver….

Immune supportLiver support

Medium relevance

Almond Mushroom · 2024 · Preprint · journal metadata

Integrating mechanism-based T cell phenotypes into a model of tumor-immune cell interactions

ABSTRACT Interactions between cancer cells and immune cells in the tumor microenvironment influence tumor growth and can contribute to the response to cancer immunotherapies. It is difficult to gain mechanistic insights into the effects of cell-cell interactions in tumors using a purely experimental approach..

OncologyImmune support

Medium relevance

Cordyceps · 2024 · Review · Current issues in molecular biology

Medicinal Mushrooms in Metastatic Breast Cancer: What Is Their Therapeutic Potential as Adjuvant in Clinical Settings?

Breast cancer (BC) is the most commonly diagnosed tumor, remaining one of the leading causes of morbidity and mortality in females worldwide, with the highest rates in Western countries..

OncologyImmune supportCognition & nervesLiver support

Medium relevance

Almond Mushroom · 2024 · Preprint · journal metadata

Meta Biome: A Multiscale Model Integrating Agent-Based Modeling and Metabolic Networks Reveals Spatial Regulation in Mucosal Microbial Communities

Mucosal microbial communities (MMCs) are complex ecosystems near the mucosal layers of the gut, essential for maintaining health and modulating disease states. Despite advances in high-throughput omics technologies, current methodologies struggle to capture the dynamic metabolic interactions and spatiotemporal….

Energy & fatigueMetabolic healthGut & microbiome

Medium relevance

Almond Mushroom · 2024 · Preprint · journal metadata

On the equivalence between agent-based and continuum models for cell population modeling. Application to glioblastoma evolution in microfluidic devices

A bstract Mathematical models are invaluable tools for understanding the mechanisms and interactions that control the behavior of complex systems. Modeling a problem as cancer evolution includes many coupled phenomena being therefore impossible to obtain sufficient experimental results to fully evaluate all possible….

OncologyImmune support

Medium relevance

Lion's Mane · 2024 · Review · Antioxidants (Basel, Switzerland)

Oxidative Stress in Spinocerebellar Ataxia Type 3 and Its Attenuation by Herbal Remedies in Traditional Chinese Medicine: A Systematic Review.

Spinocerebellar ataxia type 3 (SCA3) is an autosomal dominant neurodegenerative disorder that gives rise to motor incoordination and progressive functional disabilities. Although pharmacological interventions have revealed promising prospects in the management of SCA3, adverse effects may become unbearable..

OncologyImmune supportCognition & nervesEnergy & fatigue

Medium relevance

Almond Mushroom · 2024 · Preprint · journal metadata

Perspectives: Two Approaches in Computational Social Sciences

Big data-driven machine learning and artificial intelligence (ML/AI) is not all computational social sciences (CSS) have. Agent-based modeling (ABM) or multi-agent system (MAS) is another fundamentally different but equally useful approach in CSS..

Cognition & nerves

Medium relevance

Oyster Mushroom · 2024 · Preprint · journal metadata

Pleurotus sajor-caju (Fr.) Singer β-1,3- Glucanoligosaccharide (Ps-GOS) suppresses RANKLInduced Osteoclast Differentiation and Function in Pre-Osteoclastic RAW 264.7 Cells by Inhibiting the RANK/NFκB/cFOS/NFATc1 Signalling Pathway

Edible grey oyster mushroom, Pleurotus sajor-caju, β (1,3), (1,6) glucan possesses a wide range of biological activities, including anti-inflammation, anti- microorganisms, and antioxidant. However, its biological activity is limited by their low water solubility resulting from the high molecular weight..

OncologyImmune supportMetabolic health

Medium relevance

Reishi · 2024 · Review · Chinese journal of natural medicines

Polysaccharides from Chinese herbal medicine: a review on the hepatoprotective and molecular mechanism.

Polysaccharides, predominantly extracted from traditional Chinese medicinal herbs such as Lycium barbarum, Angelica sinensis, Astragalus membranaceus, Dendrobium officinale, Ganoderma lucidum, and Poria cocos, represent principal bioactive constituents extensively utilized in Chinese medicine..

OncologyImmune supportLiver support

Medium relevance

Reishi · 2024 · Review · International journal of biological macromolecules

Polysaccharides targeting autophagy to alleviate metabolic syndrome.

Metabolic syndrome is a prevalent non-communicable disease characterized by central obesity, insulin resistance, hypertension, hyperglycemia, and hyperlipidemia. Epidemiological statistics indicate that one-third of the world's population is affected by metabolic syndrome..

Immune supportMetabolic health

Medium relevance

Reishi · 2024 · Review · Chinese medicine

Potential of natural products and gut microbiome in tumor immunotherapy.

Immunotherapy is a novel treatment approach for malignant tumors, which has opened a new journey of anti-tumor therapy. Although some patients will show a positive response to immunotherapy, unfortunately, most patients and cancer types do not achieve an ideal response to immunotherapy..

OncologyImmune supportGut & microbiomeLiver support

Medium relevance

Reishi · 2024 · Review · Antioxidants (Basel, Switzerland)

Potentials of Natural Antioxidants in Reducing Inflammation and Oxidative Stress in Chronic Kidney Disease.

Chronic kidney disease (CKD) presents a substantial global public health challenge, with high morbidity and mortality. CKD patients often experience dyslipidaemia and poor glycaemic control, further exacerbating inflammation and oxidative stress in the kidney..

Immune supportMetabolic health

Medium relevance

Turkey Tail · 2024 · Review · Mycology

Role of white rot fungi in sustainable remediation of heavy metals from the contaminated environment.

Heavy metal contamination has severe impacts on the natural environment. The currently existing physico-chemical methods have certain limitations, restricting their wide-scale application..

Medium relevance

Almond Mushroom · 2024 · Preprint · journal metadata

Simulations probe the role of space in the interplay between drug-sensitive and drug-resistant cancer cells

The interplay between drug-sensitive and drug-resistant cancer cells has been observed to impact cell-to-cell interactions in experimental settings. However, the role that space plays in these interactions remains unclear..

Oncology

Medium relevance

Almond Mushroom · 2024 · Preprint · bioRxiv: the preprint server for biology

SMoRe GloS: An efficient and flexible framework for inferring global sensitivity of agent-based model parameters.

Agent-based models (ABMs) have become essential tools for simulating complex biological, ecological, and social systems where emergent behaviors arise from the interactions among individual agents..

Oncology

Medium relevance

Almond Mushroom · 2024 · Preprint · journal metadata

Spatially Fractionated GRID radiation potentiates immune-mediated tumor control

Abstract Background Tumor-immune interactions shape a developing tumor and its tumor immune microenvironment (TIME) resulting in either well-infiltrated, immunologically inflamed ‘hot’ tumor beds, or ‘cold’ immune deserts with low levels of infiltration..

OncologyImmune support

Medium relevance

Cordyceps · 2024 · Review · Frontiers in pharmacology

Structural and pharmacological insights into cordycepin for neoplasms and metabolic disorders.

Cytotoxic adenosine analogues were among the earliest chemotherapeutic agents utilised in cancer treatment. Cordycepin, a natural derivative of adenosine discovered in the fungus Ophiocordyceps sinensis, directly inhibits tumours not only by impeding biosynthesis, inducing apoptosis or autophagy, regulating the cell….

OncologyImmune supportMetabolic health

Medium relevance

Reishi · 2024 · Review · Phytomedicine: international journal of phytotherapy and phytopharmacology

Targeting CD8+ T cells with natural products for tumor therapy: Revealing insights into the mechanisms.

BACKGROUND: Despite significant advances in cancer immunotherapy over the past decades, such as T cell-engaging chimeric antigen receptor (CAR)-T cell therapy and immune checkpoint blockade (ICB), therapeutic failure resulting from various factors remains prevalent..

OncologyImmune support

Medium relevance

Reishi · 2024 · Review · Applied microbiology and biotechnology

The microbial biosynthesis of noncanonical terpenoids.

Terpenoids are a class of structurally complex, naturally occurring compounds found predominantly in plant, animal, and microorganism secondary metabolites. Classical terpenoids typically have carbon atoms in multiples of five and follow well-defined carbon skeletons, whereas noncanonical terpenoids deviate from these….

Medium relevance

Reishi · 2024 · Review · Phytotherapy research: PTR

The role of selected nutraceuticals in management of prediabetes and diabetes: An updated review of the literature. Part II.

We have already published a review about the results of clinical trials evaluating the effects of selected nutraceuticals on glycemia in humans. In this second part, we describe the role of other nutraceuticals involved in dysglycemia..

Metabolic health

Medium relevance

Turkey Tail · 2024 · Review · Environmental science and pollution research international

Under explored roles of microbial ligninolytic enzymes in aerobic polychlorinated biphenyl transformation.

Polychlorinated biphenyls (PCBs) are persistent organic pollutants in the environment that are responsible for many adverse health effects. Bioremediation appears to be a healthy and cost-effective alternative for remediating PCB-contaminated environments..

Metabolic health

Medium relevance

Almond Mushroom · 2024 · Preprint · journal metadata

Uplifting Moods: Augmented Reality-based Gamified Mood Intervention app with Attention Bias Modification

Attention Bias Modification (ABM) is a cost-effective emotional intervention that has the potential to be used in daily settings beyond clinical environments. However, its interactivity and user engagement are known to be limited and underexplored..

Medium relevance

Shiitake · 2020 · Case Reports · Journal of surgical case reports

A case series of intestinal obstruction secondary to shiitake mushroom intake during Chinese New Year.

Shiitake mushroom is a common ingredient in East Asian cuisines. Food processing/preparation can cause the mushroom to be soft and slimy, leading to accidental swallowing.

Gut & microbiome

Medium relevance

Almond Mushroom · 2020 · Case Reports · Veterinary and animal science

Clinical evaluation following the percutaneous transplantation of allogenic bone marrow-derived mesenchymal stem cells (aBM-MSC) in dogs affected by vertebral compression fracture.

Stem cell therapy has been extensively evaluated for its potential in managing neuronal diseases and disorders. The present study was performed to evaluate the therapeutic potential of allogenic bone marrow-derived mesenchymal stem cells (aBM-MSC) for the management of neural defects associated with vertebral….

Cognition & nerves

Medium relevance

Chaga · 2020 · Case Reports · Journal of Korean medical science

Development of End Stage Renal Disease after Long-Term Ingestion of Chaga Mushroom: Case Report and Review of Literature.

Chaga mushrooms are widely used in folk remedies and in alternative medicine. Contrary to many beneficial effects, its adverse effect is rarely reported.

Skin & hydration

Medium relevance

King Oyster · 2020 · Clinical Trial · Molecules (Basel, Switzerland)

Effects of Rich in Β-Glucans Edible Mushrooms on Aging Gut Microbiota Characteristics: An In Vitro Study.

Alterations of gut microbiota are evident during the aging process. Prebiotics may restore the gut microbial balance, with β-glucans emerging as prebiotic candidates..

Gut & microbiome

Medium relevance

Cordyceps · 2020 · Research Support, Non U.S. Gov'T · Protein expression and purification

Expression, purification and characterization of 5'-nucleotidase from caterpillar fungus by efficient genome-mining.

5'- nucleotidase (5'-NT) is a key enzyme in nucleoside/nucleotide metabolic pathway, it plays an important role in the biosynthesis of cordycepin in caterpillar fungus..

Metabolic health

Medium relevance

Shiitake · 2020 · Case Reports · The Journal of emergency medicine

Flagellate Dermatitis After Ingestion of Shiitake Mushrooms in a Healthy Female Living in the Southeastern United States.

BACKGROUND: Shiitake flagellate dermatitis is a shiitake mushroom (SM)-induced toxic dermatosis that is a widely recognized clinical phenomenon in Japan, China, and Korea but is rarely reported outside of Asia..

Skin & hydration