MycoData

In several Mediterranean countries, olive pruning residues (OLPRs) are abandoned or burned leading to several environmental problems. Valorization of these agrowastes could be a challenge for the primary decomposer Pleurotus ostreatus, turning them into edible biomass..

Gut & microbiome

High relevance

Lion's Mane · 2019 · Journal Article · International journal of biological macromolecules

A polysaccharide from cultured mycelium of Hericium erinaceus relieves ulcerative colitis by counteracting oxidative stress and improving mitochondrial function.

EP-1 is a polysaccharide with a molecular weight of approximately 3100 Da, which is extracted from the cultured mycelium of Hericium erinaceus. Its anti-ulcerative colitis activity was evaluated in experimental systems using rats with ulcerative colitis and Caco-2 cells as models for experimentation..

OncologyImmune supportEnergy & fatigueGut & microbiome

High relevance

Shiitake · 2019 · Journal Article · International journal of biological macromolecules

A protease-resistant α-galactosidase characterized by relatively acid pH tolerance from the Shitake Mushroom Lentinula edodes.

A monomeric α-galactosidase with a molecular weight of 64 kDa was purified from fresh fruiting bodies of Lentinula edodes. The purification protocol involved ion-exchange chromatography on DEAE-cellulose, CM-cellulose and Q-Sepharose and a final gel-filtration on Superdex 75..

Gut & microbiome

High relevance

Lion's Mane · 2019 · Journal Article · International immunopharmacology

A unique polysaccharide from Hericium erinaceus mycelium ameliorates acetic acid-induced ulcerative colitis rats by modulating the composition of the gut microbiota, short chain fatty acids levels and GPR41/43 respectors.

Ulcerative colitis (UC) is an idiopathic, chronic inflammatory disorder of the colonic mucosa. Risk of colorectal cancer in ulcerative colitis is increased in patients with long-standing disease compared with the general population..

OncologyImmune supportGut & microbiome

High relevance

Lion's Mane · 2019 · Research Article · Molecules (Basel, Switzerland)

Absolute Bioavailability, Tissue Distribution, and Excretion of Erinacine S in Hericium erinaceus Mycelia.

Erinacine S, so far known to have been produced only in Hericium erinaceus mycelia, has just recently been discovered and is able to reduce amyloid plaque growth and improve neurogenesis in aged brain of rats..

Cognition & nervesMetabolic healthGut & microbiomeLiver support

High relevance

Shiitake · 2019 · Research Article · Journal of clinical biochemistry and nutrition

Activation of NF-E2 p45-related factor-2 transcription and inhibition of intestinal tumor development by AHCC, a standardized extract of cultured Lentinula edodes mycelia.

It has been reported that activation of NF-E2 p45-related factor-2 (NRF2), a transcription factor, induces a variety of antioxidant enzymes, and plays an important role in preventing carcinogenesis. AHCC is a standardized extract of cultured Lentinula edodes mycelia and it has been demonstrated to improve cancer..

OncologyImmune supportGut & microbiome

High relevance

Snow Fungus · 2019 · Research Article · Mycobiology

An Enzymolysis-Assisted Agrobacterium tumefaciens-Mediated Transformation Method for the Yeast-Like Cells of Tremella fuciformis.

Agrobacterium tumefaciens-mediated transformation (ATMT), as a simple and versatile method, achieves successful transformation in the yeast-like cells (YLCs) of Tremella fuciformis with lower efficiency..

Gut & microbiomeSkin & hydration

High relevance

Turkey Tail · 2019 · Journal Article · Industrial crops and products

Biological pretreatment with Trametes versicolor to enhance methane production from lignocellulosic biomass: a metagenomic approach

The presence of poorly biodegradable components in lignocellulosic biomass limits the methane recovery in anaerobic digesters. The main reason to go for aerobic pretreatment before anaerobic digestion (AD) is to enable enzymatic cleavage of the aromatic rings in lignin by oxygen since it cannot be efficiently degraded….

Energy & fatigueGut & microbiome

High relevance

Enoki · 2019 · Journal Article · International journal of food science & technology

Characteristic of polysaccharides from Flammulina velutipes in vitro digestion under salivary, simulated gastric and small intestinal conditions and fermentation by human gut microbiota

In this study, in vitro digestion and fermentation of Flammulina velutipes ‐derived polysaccharides (FVP) were investigated. It was found that FVP mainly consisted of 48.45% glucose, 15.40% mannose, 14.60% xylose, 11.80% fucose and 9.90% galactose..

Immune supportMetabolic healthGut & microbiome

High relevance

Lion's Mane · 2019 · Research Article · Molecules (Basel, Switzerland)

Effects of Atmospheric and Room Temperature Plasma (ARTP) Mutagenesis on Physicochemical Characteristics and Immune Activity In Vitro of Hericium erinaceus Polysaccharides.

The polysaccharide is the main active substance contained in Hericium erinaceus and is commonly used in the treatment of neurasthenia, tumors, and digestive diseases. Six intracellular polysaccharide components were obtained from H..

OncologyImmune supportGut & microbiome

High relevance

Shiitake · 2019 · Journal Article · International journal of biological macromolecules

Expression of a recombinant Lentinula edodes cellobiohydrolase by Pichia pastoris and its effects on in vitro ruminal fermentation of agricultural straws.

An experiment was conducted to determine the effects of recombinant cellobiohydrolase on the hydrolysis and in vitro rumen microbial fermentation of agricultural straws including rice straw, wheat straw, and corn straw. The cellobiohydrolase from Lentinula edodes (LeCel7A) was produced in Pichia pastoris..

Gut & microbiome

High relevance

Enoki · 2019 · Journal Article · Plant disease

First Report of Cedecea neteri Causing Yellow Sticky Disease in Flammulina velutipes in China

Flammulina velutipes is one of the most popular and widely cultivated edible mushrooms in many areas of China. In the summer of 2017, a yellow sticky mass was observed on the surface of stipes and pileus of F.

Gut & microbiome

High relevance

Maitake · 2019 · Journal Article · Food & function

Grifola frondosa polysaccharides ameliorate lipid metabolic disorders and gut microbiota dysbiosis in high-fat diet fed rats.

The purpose of this study was to assess the potential effects of polysaccharides from edible mushroom Grifola frondosa (GFP) on lipid metabolic disorders and gut microbiota dysbiosis, and elucidate their possible regulatory mechanisms on lipid and cholesterol metabolism in high-fat diet (HFD)-exacerbated….

Immune supportMetabolic healthGut & microbiomeLiver support

High relevance

Turkey Tail · 2019 · Research Article · International journal of medical sciences

In Vitro Anti-proliferative and Anti-invasive Effect of Polysaccharide-rich Extracts from Trametes Versicolor and Grifola Frondosa in Colon Cancer Cells.

Colorectal cancer (CRC) is one of leading causes of mortality in western countries and novel treatment strategies are required. The medicinal application of mushrooms has been used in traditional medicine in many oriental countries..

OncologyImmune supportGut & microbiomeSkin & hydration

High relevance

Lion's Mane · 2019 · Journal Article · Food Hydrocolloids

Isolation of crude oligosaccharides from Hericium erinaceus by integrated membrane technology and its proliferative activity

In this study, isolation of crude oligosaccharides from Hericium erinaceus (CHOS), and its physicochemical properties and proliferative effects on lactic acid bacteria were investigated..

Immune supportGut & microbiome

High relevance

Enoki · 2019 · Journal Article · International journal of biological macromolecules

Preparation and in vitro absorption studies of a novel polysaccharide‑iron (III) complex from Flammulina velutipes.

Iron is essential in fundamental bioactivities, so it makes sense to improve the efficiency of iron on epithelial transport. In this work, a novel polysaccharide‑iron(III) complex (FVP-Fe(III)) was prepared from Flammulina velutipes with a specific structure..

OncologyImmune supportMetabolic healthGut & microbiome

High relevance

Snow Fungus · 2019 · Journal Article · Food Hydrocolloids

Stability, microstructure, and digestibility of whey protein isolate – Tremella fuciformis polysaccharide complexes

Manufacturing of protein-enriched beverages is an interesting field which has attracted a lot of attention from the research community. In this study, polysaccharides extracted from a mushroom (Tremella fuciformis) were used to enhance the stability of 5% whey protein isolate (WPI) solution for enriched beverage….

Immune supportGut & microbiome

High relevance

Maitake · 2019 · Research Article · International journal of molecular sciences

The Positive Effects of Grifola frondosa Heteropolysaccharide on NAFLD and Regulation of the Gut Microbiota.

: Non-alcoholic fatty liver disease (NAFLD) is a major public health problem in many countries. In this study, the ability of Grifola frondosa heteropolysaccharide (GFP) to ameliorate NAFLD was investigated in rats fed a high-fat diet (HFD)..

Immune supportMetabolic healthGut & microbiomeLiver support

High relevance

Lion's Mane · 2019 · Journal Article · International journal of biological macromolecules

Transcriptome analysis of the effects of Hericium erinaceus polysaccharide on the lymphocyte homing in Muscovy duck reovirus-infected ducklings.

Hericium erinaceus polysaccharide (HEP) is a bioactive substance present in the fruiting bodies of H. erinaceus.

Immune supportGut & microbiomeRespiratory

High relevance

Mesima · 2018 · Research Article · Oncotarget

A lethal synergy induced by phellinus linteus and camptothecin11 in colon cancer cells.

Side effects of anti-cancer drugs are always challenging for effective cancer treatments. The polysaccharides extracted from Phellinus linteus (PLGL) have been widely used in treating cancers.

OncologyImmune supportGut & microbiome

High relevance

Turkey Tail · 2018 · Journal Article · Journal of wood science

Biodegradation of diuron in artificially contaminated water and seawater by wood colonized with the white-rot fungus Trametes versicolor

We investigated the potential of white-rot fungi for bioremediation of aqueous environments contaminated with diuron (3-(3,4-dichlorophenyl)-1,1-dimethylurea). First, diuron degradation activities of several white-rot fungi (Ceriporia lacerata, Phanerochaete chrysosporium, Phanerochaete sordida, Trametes versicolor)….

Gut & microbiome

High relevance

Chaga · 2018 · Journal Article · Food research international (Ottawa, Ont.)

Effects of simulated gastrointestinal digestion in vitro on the chemical properties, antioxidant activity, α-amylase and α-glucosidase inhibitory activity of polysaccharides from Inonotus obliquus

This study was aimed to investigate the impacts of gastrointestinal digestion in vitro on the physicochemical properties and the biological activities of polysaccharides from Inonotus obliquus (UIOPS-1)..

Immune supportMetabolic healthGut & microbiome

High relevance

Shiitake · 2018 · Research Article · Frontiers in microbiology

Expression of a Recombinant Lentinula edodes Xylanase by Pichia pastoris and Its Effects on Ruminal Fermentation and Microbial Community in in vitro Incubation of Agricultural Straws.

Agricultural straws, such as rice straw, wheat straw, and corn straw, are produced abundantly every year but not utilized efficiently in China. An experiment was conducted to determine the effects of recombinant xylanase on ruminal fermentation and microbial community structure in in vitro incubation of these straws..

Gut & microbiome

High relevance

Enoki · 2018 · Journal Article · Plant disease

First Report of Ewingella americana Causing Bacterial Brown Rot Disease on Cultivated Needle Mushroom (Flammulina velutipes) in China

Needle mushroom (Flammulina velutipes) is one of the most industrially cultivated edible fungi in China. Its production is constrained by multiple abiotic and biotic stresses.

Metabolic healthGut & microbiomeRespiratory

High relevance

Snow Fungus · 2018 · Journal Article · Plant disease

First Report of Lecanicillium aphanocladii Causing Rot of Tremella fuciformis in China

The white jelly-leaf mushroom (Tremella fuciformis Berk.) is a widely consumed edible fungus in Asia, particularly in China (Stamets 2000). In 2013, fresh T.

Gut & microbiome

High relevance

Enoki · 2018 · Journal Article · Food & function

Flammulina velutipes polysaccharides improve scopolamine-induced learning and memory impairment in mice by modulating gut microbiota composition.

Flammulina velutipes polysaccharides (FVP) have been proved to be effective in improving learning and memory impairment in mice. However, their underlying mechanism remains unclear.

Immune supportCognition & nervesEnergy & fatigueGut & microbiome

High relevance

Lion's Mane · 2018 · Journal Article · International journal of biological macromolecules

Hericium erinaceus polysaccharide facilitates restoration of injured intestinal mucosal immunity in Muscovy duck reovirus-infected Muscovy ducklings.

To elucidate the effect of Hericium erinaceus polysaccharide (HEP) on the intestinal mucosal immunity in normal and Muscovy duck reovirus (MDRV)-infected Muscovy ducklings, 1-day-old healthy Muscovy ducklings were pretreated with 0.2g/L HEP and/or following by MDRV infection in this study, duodenal samples were….

Immune supportGut & microbiomeRespiratory

High relevance

Lion's Mane · 2018 · Research Article · Journal of evidence-based integrative medicine

Lactobacillus fermentum HP3-Mediated Fermented Hericium erinaceus Juice as a Health Promoting Food Supplement to Manage Diabetes Mellitus.

The current study investigated the antidiabetic property of Lactobacillus fermentum HP3-mediated fermented Hericium erinaceus juice (FHJ) using male Wistar rats with streptozotocin-induced diabetes mellitus (DM). FHJ was prepared using boiled mushroom juice and L.

Immune supportMetabolic healthGut & microbiome

High relevance

Mesima · 2018 · Journal Article · Carbohydrate polymers

Polysaccharide isolated from Phellinus linteus mycelia exerts anti-inflammatory effects via MAPK and PPAR signaling pathways.

In the present study, the anti-inflammatory function of Phellinus linteus polysaccharide (PLP) was investigated in animal and cell inflammation models, and the anti-inflammatory mechanism of PLP was also explored..

Immune supportGut & microbiome

High relevance

Mesima · 2018 · Journal Article · Carbohydrate polymers

Polysaccharides extracted from Phellinus linteus ameliorate high-fat high-fructose diet induced insulin resistance in mice.

Phellinus linteus polysaccharide (PLP) has hypoglycemic effects, but mechanisms remain unclear. Male C57BL/6 J mice were either fed a normal diet (CON) or a high-fat high-fructose diet (HFD) for 16 weeks, and starting from week 12, HFD-fed animals in PLP group were orally given PLP..

Immune supportMetabolic healthGut & microbiomeLiver support

High relevance

Shiitake · 2018 · Journal Article · Journal of the science of food and agriculture

Preservation of Ceriporiopsis subvermispora and Lentinula edodes treated wheat straw under anaerobic conditions

BACKGROUND: No attention has been paid so far to the preservation of fungal‐treated lignocellulose for longer periods. In the present study, we treated wheat straw (WS) with the white‐rot fungi Ceriporiopsis subvermispora and Lentinula edodes for 8 weeks and assessed changes in pH, chemical composition and in vitro….

Gut & microbiome

High relevance

Shiitake · 2018 · Research Article · Journal of the science of food and agriculture

Preservation of Ceriporiopsis subvermispora and Lentinula edodes treated wheat straw under anaerobic conditions.

BACKGROUND: No attention has been paid so far to the preservation of fungal-treated lignocellulose for longer periods. In the present study, we treated wheat straw (WS) with the white-rot fungi Ceriporiopsis subvermispora and Lentinula edodes for 8 weeks and assessed changes in pH, chemical composition and in vitro….

Gut & microbiome

High relevance

Yellow Morel · 2018 · Journal Article · International journal of medicinal mushrooms

Traditional Knowledge of Gucchi, Morchella esculenta (Ascomycetes), in Doda District, Jammu and Kashmir, India.

The gucchi mushroom, Morchella esculenta, commonly known as the morel, is called thunthoo in the Bhaderwahi dialect spoken in District Doda of Jammu and Kashmir, India, and is an expensive food item that grows wild and is collected manually. Its nutritive and medicinal values are acknowledged..

Gut & microbiomeSkin & hydration

High relevance

Niu-Chang-Chih · 2017 · Journal Article · Journal of ethnopharmacology

Antrodia camphorata inhibits metastasis and epithelial-to-mesenchymal transition via the modulation of claudin-1 and Wnt/β-catenin signaling pathways in human colon cancer cells.

ETHNOPHARMACOLOGICAL RELEVANCE: Antrodia camphorata (AC) is a well known traditional Chinese medicinal mushroom in Taiwan, has been used to treat various diseases including cancer..

OncologyGut & microbiome

High relevance

Niu-Chang-Chih · 2017 · Journal Article · Journal of agricultural and food chemistry

Antroquinonol, a Ubiquinone Derivative from the Mushroom Antrodia camphorata, Inhibits Colon Cancer Stem Cell-like Properties: Insights into the Molecular Mechanism and Inhibitory Targets.

Antroquinonol (ANQ) is a ubiquinone derivative from the unique mushroom Antrodia camphorata, which exhibits broad-spectrum bioactivities. The effects of ANQ on cancer stem cell-like properties in colon cancer, however, remain unclear.

OncologyGut & microbiome

High relevance

Almond Mushroom · 2017 · Journal Article · International journal of food science & technology

Effect of addition of Agaricus blazei mushroom residue to milk enriched with Omega‐3 on the prevention of lipid oxidation and bioavailability of bioactive compounds after in vitro gastrointestinal digestion

The residue from a hydroalcoholic extract of the mushroom Agaricus blazei (MAR) was evaluated for phenolic compounds, flavonoids and antioxidant activity. The ability of MAR to slow the oxidation of Omega‐3 resulting from light exposure in milk matrix, and its bioavailability after in vitro digestion was investigated..

Gut & microbiome

High relevance

Niu-Chang-Chih · 2017 · Journal Article · Molecular medicine reports

Ethanol extract of Antrodia camphorata inhibits proliferation of HCT-8 human colorectal cancer cells by arresting cell cycle progression and inducing apoptosis.

Antrodia camphorata (AC) is well known in Taiwan as a traditional Chinese medicine, with a long history of use in treating cancer and inflammation. Previous studies have revealed that AC exhibits anticancer effects in various cancer cell lines..

OncologyImmune supportGut & microbiome

High relevance

Lion's Mane · 2017 · Research Article · Oncotarget

Extracts from Hericium erinaceus relieve inflammatory bowel disease by regulating immunity and gut microbiota.

Hericium erinaceus (HE), a traditional edible mushroom, is known as a medicine food homology to ameliorate gastrointestinal diseases. To investigate whether HE is clinically effective in alleviating inflammatory bowel disease (IBD), HE extracts (polysaccharide, alcoholic extracts and whole extracts were prepared using….

OncologyImmune supportGut & microbiome

High relevance

Chaga · 2017 · Research Article · International journal of biological macromolecules

Identification of Inonotus obliquus polysaccharide with broad-spectrum antiviral activity against multi-feline viruses.

Inonotus obliquus polysaccharides (IOPs) are a potential drug for the prevention and treatment of cancer, cardiopathy, diabetes, AIDs, pancreatitis and other diseases. In this study, we found that IOP can act as a broad-spectrum antiviral drug against feline viruses in the in vitro experiment..

OncologyImmune supportMetabolic healthGut & microbiome

High relevance

Lion's Mane · 2017 · Research Article · Frontiers in immunology

Immunomodulatory Activities of a Fungal Protein Extracted from Hericium erinaceus through Regulating the Gut Microbiota.

A single-band protein (HEP3) was isolated from Hericium erinaceus using a chemical separation combined with pharmacodynamic evaluation methods. This protein exhibited immunomodulatory activity in lipopolysaccharide-activated RAW 264.7 macrophages by decreasing the overproduction of tumor necrosis factor-α, interleukin….

OncologyImmune supportGut & microbiome

High relevance

Lion's Mane · 2017 · Journal Article · Food & function

Immunomodulatory effects of Hericium erinaceus derived polysaccharides are mediated by intestinal immunology.

This study was aimed at investigating the immunomodulating activity of Hericium erinaceus polysaccharide (HEP) in mice, by assessing splenic lymphocyte proliferation (cell-mediated immunity), serum hemolysin levels (humoral immunity), phagocytic capacity of peritoneal cavity phagocytes (macrophage phagocytosis), and….

Immune supportGut & microbiome

High relevance

Chaga · 2017 · Research Article · AMB Express

Inonotus obliquus polysaccharide regulates gut microbiota of chronic pancreatitis in mice.

Polysaccharide is efficient in attenuation of metabolic ailments and modulation of gut microbiota as prebiotics. The therapeutic effect of Inonotus obliquus polysaccharide (IOP) on chronic pancreatitis (CP) in mice has been validated in our previous study..

OncologyImmune supportMetabolic healthGut & microbiome

High relevance

Shiitake · 2016 · Journal Article · Cancer immunology, immunotherapy: CII

Age-associated impairment of antitumor immunity in carcinoma-bearing mice and restoration by oral administration of Lentinula edodes mycelia extract.

Because cancer is associated with aging, immunological features in the aged should be considered in anticancer immunotherapy. In this study, we investigated antitumor immunity in aged mice using a CT26 colon carcinoma model..

OncologyImmune supportGut & microbiome

High relevance

Enoki · 2016 · Journal Article · Revista iberoamericana de micologia

Flammulina velutipes: An option for "alperujo" use.

BACKGROUND: Two-phase olive-mill wastes (or "alperujo") exhibit highly phytotoxic properties, mainly due to phenols. A valuable option for alperujo is its agricultural use, provided that no phytotoxic effects occur..

Gut & microbiome

High relevance

Lion's Mane · 2016 · Journal Article · Journal of ethnopharmacology

Haematological, biochemical and histopathological aspects of Hericium erinaceus ingestion in a rodent model: A sub-chronic toxicological assessment.

ETHNOPHARMACOLOGICAL RELEVANCE: Hericium erinaceus is a culinary-medicinal mushroom and has a long history of usage in traditional Chinese medicine as a tonic for stomach disorders, ulcers and gastrointestinal ailments..

Metabolic healthGut & microbiomeLiver support

High relevance

Shiitake · 2016 · Journal Article · Food & function

Proteomic analysis of intestinal tissues from mice fed with Lentinula edodes-derived polysaccharides.

Lentinula edodes-derived polysaccharides are well known for their immunomodulation and antitumor activities. However, the mechanisms of action have not been fully elucidated..

OncologyImmune supportGut & microbiome

High relevance

Lion's Mane · 2014 · Review · Applied microbiology and biotechnology

Medicinal properties of Hericium erinaceus and its potential to formulate novel mushroom-based pharmaceuticals.

Hericium erinaceus is an important mushroom with edible values and medicinal properties. Both the mycelium and the fruiting bodies contain many bioactive compounds with drug efficacy..

OncologyImmune supportCognition & nervesGut & microbiome

High relevance

Chaga · 2010 · Review · Journal of biomedicine & biotechnology

Anti-inflammatory effects of Inonotus obliquus in colitis induced by dextran sodium sulfate.

A total of 28 male BALB/c mice (average weight 20.7 +/- 1.6 g) were divided into 4 treatment groups and fed a commercial diet (A), a commercial diet + induced colitis by dextran sodium sulfate (DSS) (B), Inonotus obliquus (IO) administration (C), and IO administration + induced colitis by DSS (D)..

OncologyImmune supportGut & microbiome

High relevance

Maitake · 2005 · Journal Article · Phytochemistry

Grifolisin, a member of the sedolisin family produced by the fungus Grifola frondosa.

The pepstatin-insensitive carboxyl proteinase grifolisin was purified from fruiting bodies of the fungus Grifola frondosa, a maitake mushroom. The enzyme had an optimum pH of 3.0 for the digestion of hemoglobin and 2.8 for milk casein digestion..

Metabolic healthGut & microbiome

High relevance

King Oyster · 2005 · Research Article · Guangxi Agricultual Sciences

High-yielding cultivation techniques for Pleurotus eryngii in refrigerated warehouse

Metadata-grounded summary: This research article indexes research on Pleurotus eryngii in Guangxi Agricultual Sciences in 2005. MycoData maps the paper to gut & microbiome based on its title, species context, article metadata, and study classification..

Gut & microbiome