MycoData

Immune supportCognition & nervesEnergy & fatigueMetabolic health

Shiitake · 2021 · Journal Article · Applied microbiology and biotechnology

Antidepressant-like effect of Ganoderma lucidum spore polysaccharide-peptide mediated by upregulation of prefrontal cortex brain-derived neurotrophic factor.

A 28-kDa polysaccharide-peptide (PGL) with antidepressant-like activities was isolated from spores of the mushroom Ganoderma lucidum. It was unadsorbed on DEAE-cellulose.

OncologyImmune supportCognition & nerves

Lion's Mane · 2021 · Journal Article · Food & function

Apoptotic mechanisms of gastric cancer cells induced by isolated erinacine S through epigenetic histone H3 methylation of FasL and TRAIL.

Erinacine S, the new bioactive diterpenoid compound isolated from the ethanol extract of the mycelia of Hericium erinaceus, displays great health-promoting properties. However, the effects of erinacine S on inductive apoptosis in cancer cells such as gastric cancer and its molecular mechanisms remain unclear..

Immune supportCognition & nervesSkin & hydration

Niu-Chang-Chih · 2021 · Research Article · Molecules (Basel, Switzerland)

Ergosta-7,9(11),22-trien-3β-ol Rescues AD Deficits by Modulating Microglia Activation but Not Oxidative Stress.

Ergosta-7,9(11),22-trien-3β-ol (EK100) was isolated from the Taiwan-specific medicinal fungus Antrodia camphorata, which is known for its health-promotion and anti-aging effects in folk medicine. Alzheimer's disease (AD) is a major aging-associated disease..

OncologyImmune supportCognition & nerves

Shiitake · 2021 · Journal Article · Clinical nutrition (Edinburgh, Scotland)

Fungal beta-glucans as adjuvants for treating cancer patients - A systematic review of clinical trials.

BACKGROUND & AIMS: Fungal β-glucans have been considered as biological response modifiers (BRMs) promoting stimulation of immune system according to numerous scientific publications performed in vitro and in vivo. Some clinical trials involving such compounds started to be published since 1980's..

OncologyImmune supportCognition & nervesMetabolic health

Mesima · 2021 · Research Article · Experimental and therapeutic medicine

Hispidin inhibits LPS-induced nitric oxide production in BV-2 microglial cells via ROS-dependent MAPK signaling.

Neuroinflammation is associated with many neurodegenerative diseases. Abnormal activation of microglial cells in the central nervous system (CNS) is a major characteristic of neuroinflammation..

Immune supportCognition & nervesEnergy & fatigue

Oyster Mushroom · 2021 · Journal Article · Frontiers in molecular biosciences

Immobilization of Antibodies by Genetic Fusion to a Fungal Self-Assembling Adhesive Protein.

Although antibody immobilization on solid surfaces is extensively used in several applications, including immunoassays, biosensors, and affinity chromatography, some issues are still challenging. Self-assembling protein layers can be used to coat easily different surfaces by direct deposition..

Immune supportCognition & nervesGut & microbiome

Snow Fungus · 2021 · Journal Article · Journal of ethnopharmacology

Laxative effect and mechanism of Tiantian Capsule on loperamide-induced constipation in rats.

ETHNOPHARMACOLOGICAL RELEVANCE: Tiantian capsule (TTC), as a functional food, which consists of four herb medicines, including Aloe vera Burm.f. (25%), leaf juices, dried; Cucurbita moschata Duch.

Cognition & nervesEnergy & fatigueLiver support

Oyster Mushroom · 2021 · Journal Article · Biotechnologia

Relative profiling of L-tryptophan derivatives from selected edible mushrooms as psychoactive nutraceuticals to inhibit P-glycoprotein: a paradigm to contest blood-brain barrier.

Depression is a mental illness and is considered to be a global threat. It is designated as burden of disease.

Oyster Mushroom · 2021 · Journal Article · Scientific reports

Self-assembling thermostable chimeras as new platform for arsenic biosensing.

The correct immobilization and orientation of enzymes on nanosurfaces is a crucial step either for the realization of biosensors, as well as to guarantee the efficacy of the developed biomaterials..

Cognition & nervesEnergy & fatigue

Chaga · 2021 · Research Article · Current issues in molecular biology

Water Extract of Mixed Mushroom Mycelia Grown on a Solid Barley Medium Is Protective against Experimental Focal Cerebral Ischemia.

Although the individual consumption of medicinal mushrooms, including Phellinus linteus (PL), Ganoderma lucidum (GL), and Inonotus obliquus (IO), is known to be neuroprotective, the associated mechanisms underlying their therapeutic synergism on focal cerebral ischemia (fCI) have yet to be elucidated..

Immune supportCognition & nerves

Snow Fungus · 2021 · Research Article · Journal of fungi (Basel, Switzerland)

Whole Genome Sequencing and Annotation of Naematelia aurantialba (Basidiomycota, Edible-Medicinal Fungi).

Naematelia aurantialba is a rare edible fungus with both nutritional and medicinal values and especially rich in bioactive polysaccharides. However, due to the lack of genomic information, researches on the mining of active compounds, artificial breeding and cultivation, genetics, and molecular biology are limited..

Immune supportCognition & nerves

Almond Mushroom · 2023 · Research Support, Non U.S. Gov'T · Analytical chemistry

A Proof-of-Concept Sandwich Enzyme-Linked Immunoassay Development for Small Molecules.

A sandwich immunoassay theoretically exhibits higher sensitivity and specificity compared to a competitive counterpart; however, it is extremely difficult to obtain a pair of antibodies that can bind to a small molecule simultaneously, which is always thought to be a single epitope..

OncologyCognition & nerves

Almond Mushroom · 2023 · Research Support, Non U.S. Gov'T · PLoS computational biology

Calibrating agent-based models to tumor images using representation learning.

Agent-based models (ABMs) have enabled great advances in the study of tumor development and therapeutic response, allowing researchers to explore the spatiotemporal evolution of the tumor and its microenvironment..

Almond Mushroom · 2023 · Research Support, Non U.S. Gov'T · Development and psychopathology

Functional brain plasticity following childhood maltreatment: A longitudinal fMRI investigation of autobiographical memory processing.

Altered autobiographical memory (ABM) processing characterizes some individuals with experiences of childhood maltreatment. This fMRI study of ABM processing evaluated potential developmental plasticity in neural functioning following maltreatment..

Almond Mushroom · 2023 · Research Support, Non U.S. Gov'T · Proceedings. Biological sciences

Simulation and social network analysis provide insight into the acquisition of tool behaviour in hybrid macaques.

The pathways through which primates acquire skills are a central focus of cultural evolution studies. The roles of social and genetic inheritance processes in skill acquisition are often confounded by environmental factors..

Almond Mushroom · 2022 · Research Support, Non U.S. Gov'T · Insect biochemistry and molecular biology

Identification and pharmacological characterization of histamine-gated chloride channels in the fall armyworm, Spodoptera frugiperda.

Histamine-gated chloride channels (HACls) mediate fast inhibitory neurotransmission in invertebrate nervous systems and have important roles in light reception, color processing, temperature preference and light-dark cycle. The fall armyworm, Spodoptera frugiperda is a main destructive pest of grain and row crops..

Almond Mushroom · 2022 · Research Support, Non U.S. Gov'T · Journal of clinical psychology

Patterns of alliance development in cognitive behavioral therapy versus attention bias modification for social anxiety disorder: Sawtooth patterns and sudden gains.

OBJECTIVES: We examined patterns in alliance development in cognitive behavioral therapy (CBT) for social anxiety disorder (SAD) compared to attention bias modification (ABM)..

Almond Mushroom · 2021 · Research Support, Non U.S. Gov'T · Development and psychopathology

Autobiographical memory as a latent vulnerability mechanism following childhood maltreatment: Association with future depression symptoms and prosocial behavior.

OBJECTIVES: Childhood maltreatment is associated with altered neural reactivity during autobiographical memory (ABM) recall and a pattern of overgeneral memory (OGM). Altered ABM and OGM have been linked with psychopathology and poorer social functioning..

Almond Mushroom · 2021 · Brief Report · Iranian journal of veterinary research

Percutaneous transplantation of allogenic bone marrow-derived mesenchymal stem cells for the management of paraplegia secondary to Hansen type I intervertebral disc herniation in a Beagle dog.

BACKGROUND: Intervertebral disc herniation (IVDH) is one of the common causes of spinal cord injury (SCI) in dogs. It is commonly treated by performing surgical decompression that involves the removal of the extruded disc material..

Lion's Mane · 2020 · Journal Article · Mushroom Science and Biotechnology

Hericium erinaceum (Yamabushitake) extract inhibits biofilm formation and degrades mature biofilm of the periodontopathogenic bacterium Eikenella corrodens

Metadata-grounded summary: This journal article indexes research on Hericium erinaceus in Mushroom Science and Biotechnology in 2020. MycoData maps the paper to cognition & nerves based on its title, species context, article metadata, and study classification..

Almond Mushroom · 2020 · Journal Article · Frontiers in veterinary science

Variable Cognition in ABM Decision-Making: An Application to Livestock Vaccine Choice.

Modeling realistic human decision-making is an important feature of good policy design processes. The use of an agent-based modeling framework allows for quantitative human decision-models that assume fully rational agents.

Wood Ear · 2019 · Journal Article · International journal of medicinal mushrooms

Role of Aqueous Extract of the Wood Ear Mushroom, Auricularia polytricha (Agaricomycetes), in Avoidance of Haloperidol-lnduced Catalepsy via Oxidative Stress in Rats.

Haloperidol-induced catalepsy is an animal model of a psychotic disorder that may be associated with neurodegeneration and free radical damage. Auricularia polytricha is effective in both prevention and treatment of numerous types of neurological disorders..

OncologyImmune supportCognition & nervesEnergy & fatigue

Chaga · 2014 · Research Support, Non U.S. Gov'T · Journal of cellular biochemistry

3,4-dihydroxybenzalacetone protects against Parkinson's disease-related neurotoxin 6-OHDA through Akt/Nrf2/glutathione pathway.

UNLABELLED: Oxidative stress is implicated in the pathogenesis of various neurodegenerative diseases including Parkinson's disease (PD). 3,4-Dihydroxybenzalacetone (DBL) is a small catechol-containing compound isolated from Chaga (Inonotus obliquus [persoon] Pilat), and has been reported to have beneficial….

Immune supportCognition & nerves

Lion's Mane · 2020 · Review · Planta medica

A Mechanistic Review on Medicinal Mushrooms-Derived Bioactive Compounds: Potential Mycotherapy Candidates for Alleviating Neurological Disorders.

According to the World Health Organization, neurological and neurodegenerative diseases are highly debilitating and pose the greatest threats to public health. Diseases of the nervous system are caused by a particular pathological process that negatively affects the central and peripheral nervous systems..

Almond Mushroom · 2020 · Preprint · journal metadata

A systematic review of event-related potentials as outcome measures of attention bias modification

Attention bias modification (ABM) was initially developed with the goal of reducing attentional bias to threat—and subsequently anxious symptoms—in individuals with heightened anxiety. Although controversial, ABM appears to be generally effective in achieving this goal..

OncologyImmune supportCognition & nervesEnergy & fatigue

Lion's Mane · 2020 · Review · Pharmacological research

Erinacine A and related cyathane diterpenoids: Molecular diversity and mechanisms underlying their neuroprotection and anticancer activities.

The presence of a fused 5/6/7 tricyclic core characterizes the group of cyathane diterpene natural products, that include more than 170 compounds, isolated from fungi such as Cyathus africanus and Hericium erinaceus..

OncologyImmune supportCognition & nervesRespiratory

Shiitake · 2019 · Review · Journal of ethnopharmacology

Do recent research studies validate the medicinal plants used in British Columbia, Canada for pet diseases and wild animals taken into temporary care?

ETHNOPHARMACOLOGICAL RELEVANCE: There are insufficient safe and effective treatments for chronic pain in pets. In cases such as osteoarthritis there is no commercially available cure and veterinarians use NSAIDs to manage pain..

OncologyImmune supportCognition & nervesMetabolic health

Snow Fungus · 2019 · Review · Progress in molecular biology and translational science

Tremella polysaccharide: The molecular mechanisms of its drug action.

Tremella fuciformis is an edible medicinal mushroom well known as "Yiner" or "Baimuer" in China and has been used as a Chinese herb for many years. T.

Almond Mushroom · 2023 · Preprint · journal metadata

Differentiable Agent-based Epidemiology

Mechanistic simulators are an indispensable tool for epidemiology to explore the behavior of complex, dynamic infections under varying conditions and navigate uncertain environments..

Cordyceps · 2023 · Preprint · journal metadata

Early-warning of trends in commercial wildlife trade through novel machine-learning analysis of patent filing

Abstract Unsustainable wildlife trade imperils thousands of species, but efforts to identify and reduce these threats are hampered by rapidly evolving commercial markets..

Almond Mushroom · 2023 · Preprint · journal metadata

Machine learning assisted calibration of stochastic agent-based models for pandemic outbreak analysis

Abstract Mathematical modelling with agent-based models (ABMs) has gained popularity during the COVID-19 pandemic, but their complexity makes efficient and robust calibration to data challenging..

Almond Mushroom · 2023 · Preprint · journal metadata

Temporal Meta-optimiser based Sensitivity Analysis (TMSA) for Agent-Based Models: A Children’s Services Application

Abstract With current and predicted economic pressures within English Children's Services in the UK, there is a growing discourse around the development of methods of analysis using existing data to make more effective interventions and policy decisions..

Cognition & nervesEnergy & fatigueLiver support

Almond Mushroom · 2020 · Journal Article · Nonlinear dynamics, psychology, and life sciences

Applying an Agent-based Model to Simulate Just-In-Time Support for Keeping Users of eLearning Courses Motivated.

Persuasive technology can support users of self-paced eLearning courses during critical moments of low motivation. Agent-based models (ABMs) - a relatively unfamiliar phenomenon within the persuasive technology and eLearning domains- offers a potentially relevant methodology to understand when the support should be….

Almond Mushroom · 2020 · Journal Article · Acta neurologica Belgica

Community-acquired bacterial meningitis in adults: emergency department management protocol.

Acute bacterial meningitis (ABM) is a rare but disabling infectious condition that requires a performant multidisciplinary management approach. Between 70 and 90 adult patients are diagnosed with community-acquired ABM in Belgium annually, and reported case fatality rates range from 17 to 40%..

King Oyster · 2020 · Research Article · Molecules (Basel, Switzerland)

Free Amino Acids in Three Pleurotus Species Cultivated on Agricultural and Agro-Industrial By-Products.

Previous studies have demonstrated the feasibility of employing by-products of the olive and wine sectors for the production of Pleurotus mushrooms with enhanced functionalities. In this work we investigated the influence of endogenous and exogenous factors on free amino acids (FAAs) profile of Pleurotus ostreatus, P..

Cognition & nervesLiver support

Almond Mushroom · 2020 · Research Article · JMIR research protocols

Personalized Approach Bias Modification Smartphone App ("SWIPE") to Reduce Alcohol Use Among People Drinking at Hazardous or Harmful Levels: Protocol for an Open-Label Feasibility Study.

BACKGROUND: Alcohol accounts for 5.1% of the global burden of disease and injury, and approximately 1 in 10 people worldwide develop an alcohol use disorder. Approach bias modification (ABM) is a computerized cognitive training intervention in which patients are trained to "avoid" alcohol-related images and "approach"….

Cognition & nervesLiver support

Almond Mushroom · 2020 · Research Article · Clinical psychological science: a journal of the Association for Psychological Science

Randomized Controlled Trial Testing Mobile-Based Attention-Bias Modification for Posttraumatic Stress Using Personalized Word Stimuli.

Although behavioral therapies are effective for posttraumatic stress disorder (PTSD), access for patients is limited. Attention-bias modification (ABM), a cognitive-training intervention designed to reduce attention bias for threat, can be broadly disseminated using technology..

Almond Mushroom · 2020 · Journal Article · Frontiers in human neuroscience

Relationship Between Attention Bias and Psychological Index in Individuals With Chronic Low Back Pain: A Preliminary Event-Related Potential Study.

Introduction: Attention bias towards pain-related information exists in patients with chronic pain, and recently, attention bias modification (ABM) training has been administered to patients with chronic pain..

Almond Mushroom · 2020 · Journal Article · Nature medicine

Revealing COVID-19 transmission in Australia by SARS-CoV-2 genome sequencing and agent-based modeling.

In January 2020, a novel betacoronavirus (family Coronaviridae), named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was identified as the etiological agent of a cluster of pneumonia cases occurring in Wuhan City, Hubei Province, China1,2..

Almond Mushroom · 2020 · Journal Article · Internet interventions

Seeking neutral: A VR-based person-identity-matching task for attentional bias modification - A randomised controlled experiment.

BACKGROUND: Attentional bias modification (ABM) aims to reduce anxiety by attenuating bias towards threatening information. The current study incorporated virtual reality (VR) technology and 3-dimensional stimuli with a person-identity-matching (PIM) task to evaluate the effects of a VR-based ABM training on….

Almond Mushroom · 2020 · Journal Article · Scientific reports

Segregation dynamics with reinforcement learning and agent based modeling.

Societies are complex. Properties of social systems can be explained by the interplay and weaving of individual actions.

Almond Mushroom · 2020 · Journal Article · International journal of psychophysiology: official journal of the International Organization of Psychophysiology

Single session positive attention bias modification training enhances reward-related electrocortical responses in females.

Positive affect is linked to greater mental and physiological well-being. Conversely, negative affect is linked to depressive symptoms such as anhedonia.

OncologyCognition & nervesRespiratory

Almond Mushroom · 2020 · Journal Article · The Journal of international medical research

Survival analysis of afatinib versus erlotinib for individuals with advanced del19 lung adenocarcinoma with asymptomatic brain metastasis after pemetrexed-cisplatin chemotherapy: a retrospective study.

OBJECTIVE: To evaluate survival following afatinib (AF) and erlotinib (ER) treatment in advanced del19 lung adenocarcinoma (AD19LA) with asymptomatic brain metastasis (ABM) after pemetrexed-cisplatin chemotherapy (PCC)..

Almond Mushroom · 2020 · Research Article · Iranian journal of psychiatry

The Effectiveness of Attention Bias Modification with and without Trans Cranial Direct Current Stimulation in Chronic Low Back Pain.

Objective: The present study aimed to compare the effect of ABM (attention bias modification) with and without tDCS (transcranial direct current stimulation) on attention bias, pain intensity, and disability due to pain and pain-related psychological consequences, such as depression, anxiety, and stress..

Almond Mushroom · 2020 · Journal Article · Cognition & emotion

The effectiveness of touchscreen-based attentional bias modification to thin body stimuli on state rumination.

Ruminative thinking is considered a vulnerability factor for eating disorder symptomatology. Research suggests that attentional bias to body shape stimuli may serve to underpin this maladaptive form of emotion regulation..

Cognition & nervesEnergy & fatigue

Almond Mushroom · 2019 · Research Article · Frontiers in psychology

Linear Ballistic Accumulator Modeling of Attentional Bias Modification Revealed Disturbed Evidence Accumulation of Negative Information by Explicit Instruction.

In recent years, several attentional bias modification (ABM) studies have been conducted. Previous studies have suggested that explicit instruction (i.e., informing participants of the contingency of stimuli) enhances the effect of ABM.

Almond Mushroom · 2019 · Journal Article · Clinical psychological science: a journal of the Association for Psychological Science

Pinpointing mechanisms of a mechanistic treatment: Dissociable roles for overt and covert attentional processes in acute and long-term outcomes following Attention Bias Modification.

Biased patterns of attention towards threat are implicated as key mechanisms in anxiety which can be modified through automated intervention (Attention Bias Modification; ABM)..

Almond Mushroom · 2019 · Journal Article · Social cognitive and affective neuroscience

The altered early components and the decisive later process underlying attention bias modification in social anxiety: evidence from event-related potentials.

Attention bias modification (ABM) is a potential intervention in relieving social anxiety symptoms, while its underlying neural mechanisms are not yet understood. The current study included 63 college students with social anxiety..

Chaga · 2018 · Research Article · GeroScience

Lowbush cranberry acts through DAF-16/FOXO signaling to promote increased lifespan and axon branching in aging posterior touch receptor neurons.

Medicinal berries are appreciated for their health benefits, in traditional ecological knowledge and nutrition science. Determining the cellular mechanisms underlying the effects of berry supplementation may contribute to our understanding of aging..