MycoData

Yellow Morel · 2025 · Research Support, Non U.S. Gov'T · Genomics

Strategic intercropping with mulberry (Morus alba L.) predictably modulates rhizosphere microbiome assembly and enriches pathways for secondary metabolite production.

Intercropping is a key strategy for sustainable agriculture, but its effects on the rhizosphere microbiome remain poorly understood. Here, we investigated how intercropping mulberry (Morus alba L.) with functionally distinct partners-a nitrogen-fixing legume (Pisum sativum), a saprotrophic fungus (Morchella….

Turkey Tail · 2025 · Evaluation Study · Fungal biology

Systematic evaluation of fluoride quantification methods identifies an appropriate measurement for studying fungal defluorination of per- and Polyfluoroalkyl substances.

The large-scale manufacturing and disposal of Per- and Polyfluoroalkyl substances (PFASs) are causing global concerns, and investigations are needed to understand their ecological impacts. Saprotrophic fungi are dominant nutrient recyclers in ecosystems, while their roles in transforming PFAS remain largely untapped..

Enoki · 2025 · Comparative Study · Ultrasonics sonochemistry

The effects of three physical modifications on the structural and functional characteristics of soluble dietary fibers: comparison among ultrasound, ball milling and cold plasma treatments.

This work studied three physical modifications, including ultrasound (US), ball-milling (BM), and cold plasma (CP) on Flammulina velutipes soluble dietary fibres (FV-SDF) regarding the structural and functional properties..

Turkey Tail · 2024 · Research Support, Non U.S. Gov'T · Bioorganic chemistry

"Novel chemo-enzymatic synthesis, structural elucidation and first antiprotozoal activity profiling of the atropoisomeric dimers of trans-8-Hydroxycalamenene".

Leishmaniasis and malaria are two debilitating protozoan diseases affecting millions globally, particularly in tropical and subtropical regions. Current therapeutic options face significant challenges due to emerging drug-resistant strains, necessitating the discovery of novel antiprotozoal agents..

Turkey Tail · 2024 · Research Support, Non U.S. Gov'T · ACS applied bio materials

Artificial Manganese Metalloenzymes with Laccase-like Activity: Design, Synthesis, and Characterization.

Laccase is an oxidase of great industrial interest due to its ability to catalyze oxidation processes of phenols and persistent organic pollutants. However, it is susceptible to denaturation at high temperatures, sensitive to pH, and unstable in the presence of high concentrations of solvents, which is a issue for….

Turkey Tail · 2024 · Research Support, Non U.S. Gov'T · Cell reports

Biochemical and structural characterization of enzymes in the 4-hydroxybenzoate catabolic pathway of lignin-degrading white-rot fungi.

White-rot fungi (WRF) are the most efficient lignin-degrading organisms in nature. However, their capacity to use lignin-related aromatic compounds, such as 4-hydroxybenzoate, as carbon sources has only been described recently..

Oyster Mushroom · 2024 · Research Support, Non U.S. Gov'T · Journal of hazardous materials

Comparative genomics of fungal mutants provides a systemic view of extreme cadmium tolerance in eukaryotic microbes.

Whether eukaryotic organisms can evolve for higher heavy metal resistance in laboratory conditions remains unknown. In this study, we challenged a macrofungi, Pleurotus ostreatus, in a designed microbial evolution and growth arena (MEGA)-plate with an extreme Cd gradient..

Shiitake · 2024 · Comparative Study · Food chemistry

Comparison of primary and secondary metabolites and antioxidant activities by solid-state fermentation of Apios americana Medikus with different fungi.

This study compared the nutritional components, isoflavones, and antioxidant activities by solid-sate fermentation of Apios americana Medikus (AAM) with seven different fungi..

Cognition & nervesEnergy & fatigue

Oyster Mushroom · 2024 · Comparative Study · Sensors (Basel, Switzerland)

Deep Learning-Based Classification of Macrofungi: Comparative Analysis of Advanced Models for Accurate Fungi Identification.

This study focuses on the classification of six different macrofungi species using advanced deep learning techniques. Fungi species, such as Amanita pantherina, Boletus edulis, Cantharellus cibarius, Lactarius deliciosus, Pleurotus ostreatus and Tricholoma terreum were chosen based on their ecological importance and….

Oyster Mushroom · 2024 · Research Support, Non U.S. Gov'T · Scientific reports

Degradation of edible mushroom waste by Hermetia illucens L. and consequent adaptation of its gut microbiota.

The edible fungus industry is one of the pillar industries in the Yunnan-Guizhou Plateau, China. The expansion of the planting scale has led to the release of various mushroom residues, such as mushroom feet, and other wastes, which are not treated adequately, resulting in environmental pollution..

Shiitake · 2024 · English Abstract · Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan

Elucidation of Coloring Molecule Using a Simple Identification Method with a Color Reaction for Omphalotus japonicus

For Omphalotus japonicus, the coloring molecule was found and characterized using a simple method of identification with a color reaction. The compound that chang color under basic conditions was isolated from a methanolic extract of O.

Oyster Mushroom · 2024 · Research Support, Non U.S. Gov'T · Journal of food protection

Evaluation of White Rot Fungus to Control Growth of Escherichia coli in Cattle Manure.

Biological soil amendments of animal origin, such as aqueous dairy manure, may be contaminated with microbial pathogens that can subsequently result in contaminated soil, water runoff, and crops. Multiple mitigation strategies are being evaluated to reduce these risks..

Cognition & nervesMetabolic health

Lion's Mane · 2024 · Research Support, Non U.S. Gov'T · CNS neuroscience & therapeutics

Exploring the Synergistic Effects of Erinacines on Microglial Regulation and Alzheimer's Pathology Under Metabolic Stress.

BACKGROUND: Hericium erinaceus mycelium and its constituents, erinacines A and S, have shown neuroprotective effects in APP/PS1 transgenic mice; however, the precise mechanisms by which they modulate microglial phenotypes remain unclear..

Oyster Mushroom · 2024 · Research Support, Non U.S. Gov'T · Food research international (Ottawa, Ont.)

Flours from fermented lentil and quinoa grains as ingredients with new techno-functional properties.

The need to provide novel, nutritious plant-based products requires seeking high-value, sustainable protein sources, like quinoa and lentils, having an increased digestibility and lacking antinutrients. Fungal fermentation has evidenced enhanced nutritional value of flours obtained from these grains..

Oyster Mushroom · 2024 · Research Support, Non U.S. Gov'T · Toxins

Fungal Laccases and Fumonisin Decontamination in Co-Products of Bioethanol from Maize.

Maize (Zea mays L.) may be infected by Fusarium verticillioides and F. proliferatum, and consequently contaminated with fumonisins (FBs), as well as the co-products of bioethanol intended for animal feed.

Reishi · 2024 · Research Support, Non U.S. Gov'T · Toxicology and applied pharmacology

Ganoderic acid T, a Ganoderma triterpenoid, modulates the tumor microenvironment and enhances the chemotherapy and immunotherapy efficacy through downregulating galectin-1 levels.

Ganoderic acid T (GAT), a triterpenoid molecule of Ganoderma lucidum, exhibits anti-cancer activity; however, the underlying mechanisms remain unclear. Therefore, in this study, we aimed to investigate the anti-cancer molecular mechanisms of GAT and explore its therapeutic applications for cancer treatment..

OncologyImmune support

Immune supportCognition & nervesSkin & hydration

Lion's Mane · 2024 · Research Support, Non U.S. Gov'T · Biochemical and biophysical research communications

Hericenone C attenuates the second phase of formalin-induced nociceptive behavior by suppressing the accumulation of CD11c-positive cells in the paw epidermis via phosphorylated P65.

Hericenone C is one of the most abundant secondary metabolites derived from Hericium erinaceus, under investigation for medicinal properties. Here, we report that Hericenone C inhibits the second phase of formalin-induced nociceptive behavior in mice..

Turkey Tail · 2024 · Research Support, Non U.S. Gov'T · Journal of hazardous materials

Inhibit or promote? Trade-off effect of dissolved organic matter on the laccase-mediator system.

A biocatalytic system comprising fungal laccase and mediators can generate phenol radicals and efficiently eliminate various triarylmethane dyes. This study systematically explores the kinetic impact of dissolved organic matter (DOM), represented by humic substance (HS consisting of 90% fulvic acid, from lignite), on….

Turkey Tail · 2024 · Research Support, Non U.S. Gov'T · Biomolecules

Laccase-Mediated Oxidation of Phenolic Compounds from Wine Lees Extract towards the Synthesis of Polymers with Potential Applications in Food Packaging.

Laccase from Trametes versicolor was applied to produce phenolic polymeric compounds with enhanced properties, using a wine lees extract as the phenolic source. The influence of the incubation time on the progress of the enzymatic oxidation and the yield of the formed polymers was examined..

Turkey Tail · 2024 · Research Support, Non U.S. Gov'T · Toxins

New Insights into Interactions between Mushroom Aegerolysins and Membrane Lipids.

Aegerolysins are a family of proteins that recognize and bind to specific membrane lipids or lipid domains; hence they can be used as membrane lipid sensors. Although aegerolysins are distributed throughout the tree of life, the most studied are those produced by the fungal genus Pleurotus..

Oyster Mushroom · 2024 · Research Support, Non U.S. Gov'T · Fungal biology

Persistent polycyclic aromatic hydrocarbons removal from sewage sludge-amended soil through phytoremediation combined with solid-state ligninolytic fungal cultures.

Polycyclic aromatic hydrocarbons (PAHs) are widely present in the environment, causing increasing concern because of their impact on soil health, food safety and potential health risks..

Reishi · 2024 · Research Support, Non U.S. Gov'T · Mycologia

Phylogenetic analysis and morphological characteristics of laccate Ganoderma specimens in Finland.

The Ganoderma lucidum complex includes fungi with similar morphologies but which are thought to represent different species. The lack of available type material and associated absence of multiple locus sequence data has complicated identification of these fungi..

Reishi · 2024 · Brief Report · Pharmaceuticals (Basel, Switzerland)

Selective Antineoplastic Potential of Fractionated Caribbean Native Ganoderma Species Extracts on Triple-Negative Breast Cancer Cells.

Triple-negative breast cancer (TNBC) is an aggressive subtype characterized by the absence of estrogen receptor, progesterone receptor, and human epidermal growth factor receptor type 2 expression..

OncologySkin & hydration

Reishi · 2024 · Research Support, Non U.S. Gov'T · G3 (Bethesda, Md.)

Whole-genome sequencing and comparative genomic analyses of the medicinal fungus Sanguinoderma infundibulare in Ganodermataceae.

Sanguinoderma infundibulare is a newly discovered species of Ganodermataceae known to have high medicinal and ecological values. In this study, the whole-genome sequencing and comparative genomic analyses were conducted to further understand Ganodermataceae's genomic structural and functional characteristics..

Lion's Mane · 2023 · Research Article · Journal of agricultural and food chemistry

"Fruiting Liquid" of Mushroom-Forming Fungi, A Novel Source of Bioactive Compounds - Fruiting-Body Inducer and HIF and Axl Inhibitors.

In general, mushroom-forming fungi secrete liquid on the surface of mycelia just before fruiting-body formation. However, no researchers in mushroom science have paid attention to the liquid until now..

Turkey Tail · 2023 · Research Article · Biotechnology reports (Amsterdam, Netherlands)

A high throughput screening process and quick isolation of novel lignin-degrading microbes from large number of natural biomasses.

High throughput screening approaches can significantly speed up the identification of novel enzymes from natural microbial consortiums. A two-step high throughput screening process was proposed and explored to screen lignin-degrading microorganisms..

Energy & fatigueLiver support

Reishi · 2023 · Journal Article · Phytomedicine: international journal of phytotherapy and phytopharmacology

A tri-herb formulation protects against ethanol-induced mouse liver injury and downregulates mitogen-activated protein kinase phosphatase 1.

BACKGROUND: A tri-herb formulation comprising Ganoderma (the dried fruiting body of Ganoderma lucidum), Puerariae Thomsonii Radix (the dried root of Pueraria thomsonii) and Hoveniae Semen (the dried mature seed of Hovenia acerba) -GPH for short- has been using for treating liver injury; however, the pharmacological….

Turkey Tail · 2023 · Research Article · Frontiers in fungal biology

Aerobic H2 production related to formate metabolism in white-rot fungi.

Biohydrogen is mainly produced by anaerobic bacteria, anaerobic fungi, and algae under anaerobic conditions. In higher eukaryotes, it is thought that molecular hydrogen (H2) functions as a signaling molecule for physiological processes such as stress responses..

OncologyImmune supportGut & microbiomeLiver support

Reishi · 2023 · Journal Article · BMC cancer

AGA induces sub-G1 cell cycle arrest and apoptosis in human colon cancer cells through p53-independent/p53-dependent pathway.

BACKGROUND: Despite the advancement in chemotherapeutic drugs for colon cancer treatment, it is still a life-threatening disease worldwide due to drug resistance. Therefore, an urgently needed to develop novel drugs for colon cancer therapies..

Chaga · 2023 · Journal Article · Chemistry & biodiversity

Antifungal Activity of Cadinane-Type Sesquiterpenes from Eupatorium adenophorum against Wood-Decaying Fungi.

The present study aimed to evaluate the antifungal activities of Eupatorium adenophorum against four strains of wood-decaying fungi, including Inonotus hispida, Inonotus obliquus, and Inonotus cuticularis. Bioguided isolation of the methanol extract of E..

Oyster Mushroom · 2023 · Journal Article · Polymers

Antifungal Activity of Chitosan/Poly(Ethylene Oxide) Blend Electrospun Polymeric Fiber Mat Doped with Metallic Silver Nanoparticles.

In this work, the implementation of advanced functional coatings based on the combination of two compatible nanofabrication techniques such as electrospinning and dip-coating technology have been successfully obtained for the design of antifungal surfaces..

Energy & fatigueGut & microbiome

Oyster Mushroom · 2023 · Journal Article · Journal of basic microbiology

Application of solid-state fermentation using mushrooms for the production of animal feed.

The increasing growth of agroindustrial activity resulting in excessive amounts of agriwaste has led to the accumulation of a large quantity of lignocellulosic residues all over the world, in particular in deforestation initiatives for the removal of invasive trees in South Africa..

Oyster Mushroom · 2023 · Journal Article · Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering

Assessing three industrially produced fungi for the bioremediation of diclofenac.

Diclofenac is an emerging pollutant: toxic, persistent, and bioaccumulative, present in several environmental niches in a concentration of parts per million. This pharmaceutical's biological removal was reported with various fungal species, showing promissory results..

Metabolic health

Oyster Mushroom · 2023 · Research Article · Foods (Basel, Switzerland)

Assessment of Chemical, Physico-Chemical and Sensory Properties of Low-Sodium Beef Burgers Formulated with Flours from Different Mushroom Types.

It is now widely demonstrated that excessive salt consumption can cause various health problems, and meat products are among the foods most consumed with a high salt content..

Lion's Mane · 2023 · Research Article · Tropical life sciences research

Benefits of Erinacines from Different Cultivate Formulas on Cognitive Deficits and Anxiety-Like Behaviour in Mice with Trimethyltin-Induced Toxicity.

We investigated the neurological effects of the varied erinacine composition of different mycelia cultures in mice with trimethyltin (TMT)-induced neurodegeneration. Forty male ICR mice were randomly divided into five groups of Sham-veh, TMT-veh, TMT-EME, TMT-EMR and TMT-EME/R..

Cognition & nerves

Oyster Mushroom · 2023 · Journal Article · Frontiers in bioengineering and biotechnology

Biohybrids: Textile fibres provide scaffolds and highways for microbial translocation.

Introduction: Living materials (biohybrids, textile-microbial hybrids, hybrid living materials) have gained much attention in recent years with enormous potential for applications in biomedical science, the built environment, construction and architecture, drug delivery and as environmental biosensors..

Liver support

Turkey Tail · 2023 · Journal Article · Biodegradation

Biological control of some wood-decay fungi with antagonistic fungi.

One of the most important biological factors that damage wood materials are wood-decay fungi (WDF). Chemical preservatives have traditionally been the most effective method for controlling WDF.

Oyster Mushroom · 2023 · Journal Article · Chemosphere

Bioremediation of the synthetic musk compounds Galaxolide and Tonalide by white rot fungal strain-assisted phytoremediation in biosolid-amended soil.

The study was aimed to conduct the bioremediation of synthetic musks by four species of white rot fungi combined with phytoremediation (Zea mays) in biosolid-amended soils where only Galaxolide (HHCB) and Tonalide (AHTN) were found as other musks were below the detection limit (0.5-2 μg/kg dw)..

Oyster Mushroom · 2023 · Journal Article · Applied soil ecology: a section of Agriculture, Ecosystems & Environment

Bioremediation study of a hydrocarbon-contaminated soil by profiling aromatic and aliphatic chains

Efficient decontamination of oil contaminated soils is not always easy, especially when the contamination is aged. In this work, we have opted for bioremediation techniques, with a low environmental impact, whose treatments were selected according to the area and soil to be treated..

OncologyImmune supportGut & microbiome

Mesima · 2023 · Research Article · Biomedicines

Blockade of the SRC/STAT3/BCL-2 Signaling Axis Sustains the Cytotoxicity in Human Colorectal Cancer Cell Lines Induced by Dehydroxyhispolon Methyl Ether.

Colorectal cancer (CRC) is the third most prevalent human cancer globally. 5-Fluorouracil (5-FU)-based systemic chemotherapy is the primary strategy for advanced CRC treatment, yet is limited by poor response rate..

Turkey Tail · 2023 · Research Article · Nanomaterials (Basel, Switzerland)

Cellulose Nano Crystals (CNC) as Additive for a Bio-Based Waterborne Acrylic Wood Coating: Decay, Artificial Weathering, Physical and Chemical Tests.

Wood coatings prolong the service life of wood-based products, but they are usually of synthetic origin. The aim of the present article is to reduce the fossil-based compounds in a commercial waterborne acrylic coating by CNC addition and to test its performance..

Oyster Mushroom · 2023 · Research Article · Scientific reports

Characterization and nutritional valorization of agricultural waste corncobs from Italian maize landraces through the growth of medicinal mushrooms.

The research investigates the potential use of maize cobs (or corncobs) from five genotypes, including the B73 inbred line and four locally cultivated landraces from Northern Italy, as substrate for implementing Solid State fermentation processes with four Medicinal Mushrooms (MMs)..

Zhu Ling · 2023 · Research Article · Molecules (Basel, Switzerland)

Chemical Profile Determination and Quantitative Analysis of Components in Oryeong-san Using UHPLC-Q-Orbitrap-MS and UPLC-TQ-MS/MS.

In this study, a method to both qualitatively and quantitively analyze the components of Oryeong-san (ORS), which is composed of five herbal medicines (Alisma orientale Juzepzuk, Polyporus umbellatus Fries, Atractylodes japonica Koidzumi, Poria cocos Wolf, and Cinnamomum cassia Presl) and is prescribed in traditional….

Almond Mushroom · 2023 · Research Article · Daru: journal of Faculty of Pharmacy, Tehran University of Medical Sciences

Clove volatile oil-loaded nanoemulsion reduces the anxious-like behavior in adult zebrafish.

BACKGROUND: Clove volatile oil (CVO) and its major compound, eugenol (EUG), have anxiolytic effects, but their clinical use has been impaired due to their low bioavailability. Thus, their encapsulation in nanosystems can be an alternative to overcome these limitations..

Immune support

OncologyImmune supportEnergy & fatigueMetabolic health

Niu-Chang-Chih · 2023 · Journal Article · Archives of toxicology

Coenzyme Q0 defeats NLRP3-mediated inflammation, EMT/metastasis, and Warburg effects by inhibiting HIF-1α expression in human triple-negative breast cancer cells.

Coenzyme Q0 (CoQ0) is a derivative quinone from Antrodia camphorata (AC) that exerts anticancer activities. This study examined the anticancer attributes of CoQ0 (0-4 µM) on inhibited anti-EMT/metastasis and NLRP3 inflammasome, and altered Warburg effects via HIF-1α inhibition in triple-negative breast cancer….

Reishi · 2023 · Journal Article · Journal of magnetic resonance (San Diego, Calif.: 1997)

Combination of peak-picking and binning for NMR-based untargeted metabonomics study.

In NMR-based untargeted metabolomic studies, 1H NMR spectra are usually divided into equal bins/buckets to diminish the effects of peak shift caused by sample status or instrument instability, and to reduce the number of variables used as input for the multivariate statistical analysis..

Shiitake · 2023 · Journal Article · Heliyon

Combined transcriptomics and metabolomics analysis reveals the molecular mechanism of heat tolerance of Le023M, a mutant in Lentinulaedodes

Lentinula edodes, one of the most highly regarded edible mushrooms in China, is susceptible to damage from high temperatures. However, a mutant strain derived from L.

Metabolic health

Shiitake · 2023 · Research Article · Heliyon

Combined transcriptomics and metabolomics analysis reveals the molecular mechanism of heat tolerance of Le023M, a mutant in Lentinulaedodes.

Lentinula edodes, one of the most highly regarded edible mushrooms in China, is susceptible to damage from high temperatures. However, a mutant strain derived from L.

Metabolic health