MycoData

In this work, the laccase from Trametes versicolor was immobilized in highly porous silica monoliths (0.6-cm diameter, 0.5-cm length). These monoliths feature a unique homogeneous network of interconnected macropores (20 μm) with mesopores (20 nm) in the skeleton and a high specific surface area (330 m2/g)..

Energy & fatigue

Medium relevance

Oyster Mushroom · 2022 · Journal Article · Foods (Basel, Switzerland)

Exploring the Impact of Solid-State Fermentation on Macronutrient Profile and Digestibility in Chia (Salvia hispanica) and Sesame (Sesamum Indicum) Seeds.

Fermentation of plant-based substrates with edible fungi enhances the nutrient profile and digestibility, but it has been scarcely applied to edible seeds, which are rich in healthy lipids. In this study, chia and sesame seeds were solid-state fermented with Pleurotus ostreatus, followed by drying and milling..

Gut & microbiome

Medium relevance

Turkey Tail · 2022 · Journal Article · The Science of the total environment

Extracellular laccase-activated humification of phenolic pollutants and its application in plant growth.

Humification processes of phenolic pollutants may play a profound role in environment purification and plant growth. However, little literature is performed to explore exoenzyme-driven humification to polymerize 17β-estradiol (E2) and humic constituents (HCs), and the effects of their polymeric precipitates on plant….

Energy & fatigue

Medium relevance

Enoki · 2022 · Research Article · Frontiers in nutrition

FIP-fve Stimulates Cell Proliferation and Enhances IL-2 Release by Activating MAP2K3/p38α (MAPK14) Signaling Pathway in Jurkat E6-1 Cells.

FIP-fve, a fungal fruiting body protein from Flammulina velutipes, has potential immunomodulatory properties. Here, we investigated the immunomodulation mechanism of FIP-fve in Jurkat E6-1 cells by conducting a cell viability assay and IL-2 release assay..

Immune support

Medium relevance

Enoki · 2022 · Journal Article · Plant disease

First Report of Cobweb Disease in Oudemansiella raphanipes Caused by Cladobotryum varium in Beijing, China

Oudemansiella raphanipes is an edible mushroom with medicinal properties, which has been recently cultivated throughout China (Hao et al. 2016).

Gut & microbiome

Medium relevance

Enoki · 2022 · Research Article · Frontiers in microbiology

Flammulina velutipes Polysaccharides Modulate Gut Microbiota and Alleviate Carbon Tetrachloride-Induced Hepatic Oxidative Injury in Mice.

A carbon tetrachloride-induced acute liver injury mouse model is used to study the regulation of gut microbiota and hepatoprotective effect of polysaccharides from Flammulina velutipes (FVPs)..

Immune supportMetabolic healthGut & microbiomeLiver support

Medium relevance

Turkey Tail · 2022 · Journal Article · Talanta

Fluorescent enzymatic assay for direct total polyphenol determination in food-related samples.

A direct and simple fluorescent assay for the total polyphenol determination based on the bioconjugate formed between the laccase enzyme (TvL from Trametes versicolor) and carbon nanodots (CD) is developed..

Medium relevance

Enoki · 2022 · Research Article · Frontiers in microbiology

FTX271: A potential gene resource for plant antiviral transgenic breeding.

Flammutoxin (FTX), as well as its precursor TDP, is a protein from Flammulina velutipes with antiviral activity. Transgenic tobacco with the FTX271 (gene of FTX or TDP) can not only delay the onset time of symptoms but also alleviate the symptoms caused by tobacco mosaic virus (TMV), but the mechanism is still….

Energy & fatigueRespiratory

Medium relevance

Turkey Tail · 2022 · Journal Article · Advanced materials (Deerfield Beach, Fla.)

Functional Coating from Amyloid Superwetting Films.

Tailoring the hydrophilicity of solid surfaces with a strong affinity to water has been extensively explored in the last 20 years, but studies have been limited to the single function of wettability..

Energy & fatigue

Medium relevance

Turkey Tail · 2022 · Journal Article · Industrial crops and products

Functionalisation of organosolv lignin by enzymatic demethylation for bioadhesive formulation

Bio-based adhesives offer a sustainable alternative to formaldehyde-based adhesives, which is the most common product applied in wood-based panel manufacturing. Despite the undeniable interest in lignin as a bulk chemical for the synthesis of bio-based adhesives, the main problem is its low reactivity..

Medium relevance

Oyster Mushroom · 2022 · Journal Article · iScience

Fungal glycoside hydrolase family 44 xyloglucanases are restricted to the phylum Basidiomycota and show a distinct xyloglucan cleavage pattern.

Xyloglucan is a prominent matrix heteropolysaccharide binding to cellulose microfibrils in primary plant cell walls. Hence, the hydrolysis of xyloglucan facilitates the overall lignocellulosic biomass degradation.

Immune support

Medium relevance

Turkey Tail · 2022 · Journal Article · Bioresource technology

Fungal pretreatment parameters for improving methane generation from anaerobic digestion of corn silage.

Corn silage was treated by white rot fungi (WRF) to investigate the effect of pretreatment on material's ability to produce methane in anaerobic digestion (AD). The selective fungi Pleurotus ostreatus and Dichomitus squalens promoted biogas generation, whereas the non-selective Trametes versicolor and Irpex lacteus….

Gut & microbiome

Medium relevance

Reishi · 2022 · Journal Article · Journal of fungi (Basel, Switzerland)

Fungal-Modified Lignin-Enhanced Physicochemical Properties of Collagen-Based Composite Films.

Renewable and biodegradable materials have attracted broad attention as alternatives to existing conventional plastics, which have caused serious environmental problems. Collagen is a potential material for developing versatile film due to its biosafety, renewability, and biodegradability..

Energy & fatigueSkin & hydration

Medium relevance

Reishi · 2022 · Journal Article · Aging cell

Ganoderic acid D prevents oxidative stress-induced senescence by targeting 14-3-3ε to activate CaM/CaMKII/NRF2 signaling pathway in mesenchymal stem cells.

Stem cell senescence is an important cause of aging. Delaying senescence may present a novel way to combat aging and age-associated diseases.

Energy & fatigueSkin & hydration

Medium relevance

Oyster Mushroom · 2022 · Journal Article · eLife

Gene age shapes the transcriptional landscape of sexual morphogenesis in mushroom-forming fungi (Agaricomycetes).

Multicellularity has been one of the most important innovations in the history of life. The role of gene regulatory changes in driving transitions to multicellularity is being increasingly recognized; however, factors influencing gene expression patterns are poorly known in many clades..

Medium relevance

Oyster Mushroom · 2022 · Journal Article · Biomimetics (Basel, Switzerland)

Growth and Mechanical Characterization of Mycelium-Based Composites towards Future Bioremediation and Food Production in the Material Manufacturing Cycle.

Today's architectural and agricultural practices negatively impact the planet. Mycelium-based composites are widely researched with the aim of producing sustainable building materials by upcycling organic byproducts..

Medium relevance

Mesima · 2022 · Research Article · International journal of molecular sciences

Hispolon Cyclodextrin Complexes and Their Inclusion in Liposomes for Enhanced Delivery in Melanoma Cell Lines.

Hispolon, a phenolic pigment isolated from the mushroom species Phellinus linteus, has been investigated for anti-inflammatory, antioxidant, and anticancer properties; however, low solubility and poor bioavailability have limited its potential clinical translation..

OncologyImmune supportLiver support

Medium relevance

Mesima · 2022 · Research Article · International journal of molecular sciences

Hispolon Methyl Ether, a Hispolon Analog, Suppresses the SRC/STAT3/Survivin Signaling Axis to Induce Cytotoxicity in Human Urinary Bladder Transitional Carcinoma Cell Lines.

Bladder cancer is a leading human malignancy worldwide. Signal transducer and activator of transcription (STAT) 3 is an oncogenic transcription factor commonly hyperactivated in most human cancers, including bladder cancer..

OncologyImmune support

Medium relevance

Oyster Mushroom · 2022 · Journal Article · Scientific reports

Immunomodulatory activity of extracts from five edible basidiomycetes mushrooms in Wistar albino rats.

Mushrooms are nutritious foods that are widely cultivated all over the world. They are rich in a range of compounds linked to improving functions of the immune system including carotenoids, alkaloids, lectins, enzymes, folates, fats, organic acids, minerals, polysaccharides, phenolics, proteins, tocopherols,….

OncologyImmune support

Medium relevance

Mesima · 2022 · Research Article · Pharmaceutics

Immunomodulatory Effect of Hispolon on LPS-Induced RAW264.7 Cells and Mitogen/Alloantigen-Stimulated Spleen Lymphocytes of Mice.

Hispolon is a potent anticancer, anti-inflammatory, antioxidant, and antidiabetic agent isolated from Phellinus linteus, an oriental medicinal mushroom. However, the immunomodulatory mechanisms by which hispolon affects macrophages and lymphocytes remain poorly characterized..

OncologyImmune supportEnergy & fatigueMetabolic health

Medium relevance

Oyster Mushroom · 2022 · Journal Article · Foods (Basel, Switzerland)

Impact of Freeze- and Spray-Drying Microencapsulation Techniques on β-Glucan Powder Biological Activity: A Comparative Study.

The study compares the impact of freeze- and spray-drying (FD, SD) microencapsulation methods on the content of β-glucan, total polyphenols (TP), total flavonoids (TF), phenolic acids (PA), and antioxidant activity (AA) in commercially β-glucan powder (Pleurotus ostreatus) using maltodextrin as a carrier..

Medium relevance

Turkey Tail · 2022 · Journal Article · The Science of the total environment

Impact of lignocellulosic waste-immobilised white-rot fungi on enhancing the development of 14C-phenanthrene catabolism in soil.

In this study, an investigation was carried out to explore the the impact of white-rot fungi (WRF) on enhancing the development of phenanthrene catabolism in soil over time (1, 25, 50, 75 and 100 d). The WRF were immobilised on spent brewery grains (SBG) prior to inoculation to the soil..

Medium relevance

Turkey Tail · 2022 · Research Article · Royal Society open science

In vitro cell composition identification of wood decay fungi by Fourier transform infrared spectroscopy.

Decay pathogens follow dissimilar metabolic mechanisms to cause irreversible damage to woody tissues. The objective of this study is to perform inter- and intra-species microbial cell structural comparison using attenuated total reflectance Fourier transform infrared spectroscopy..

Energy & fatigueMetabolic healthGut & microbiome

Medium relevance

Turkey Tail · 2022 · Journal Article · Bioelectrochemistry (Amsterdam, Netherlands)

Influence of different covalent immobilization protocols on electroanalytical performance of laccase-based biosensors.

This paper presents a simple and effective flow-through electrochemical biosensor, consisting of Trametes versicolor laccase (Lac)-based mini-reactor and a tubular detector of silver solid amalgam (TD-AgSA), capable of rapid and selective detection of phenolic compounds..

Energy & fatigue

Medium relevance

Turkey Tail · 2022 · Journal Article · Chemosphere

Inhibition mechanisms of Fe2+/Fe3+ and Mn2+ on fungal laccase-enabled bisphenol a polyreaction.

Bisphenol A (BPA) is regarded as an endocrine disruptor associated with negative health effects in animals and humans. Laccase from white-rot fungus can enable BPA oxidation and auto-polymerization to circumvent its biotoxicity, but the work concerning the effect mechanisms of divalent and trivalent metal ions (MIs)….

Medium relevance

Chaga · 2022 · Research Article · Experimental and therapeutic medicine

Inonotsuoxide B suppresses hepatic stellate cell activation and proliferation via the PI3K/AKT and ERK1/2 pathway.

Hepatic stellate cells (HSCs) serve a pivotal role in the formation and degradation of the extracellular matrix during liver fibrosis. Inonotsuoxide B is a tetracyclic triterpenoid that can be extracted from Inonotus obliquus and has been previously reported to inhibit the growth of liver and gastric cancer cells..

OncologyEnergy & fatigueLiver supportSkin & hydration

Medium relevance

Turkey Tail · 2022 · Journal Article · Environmental research

Insolubilization of Tramates versicolor laccase as cross-linked enzyme aggregates for the remediation of trace organic contaminants from municipal wastewater.

The novelty of this study deals with the biocatalytic treatment of trace organic contaminants (TrOCs) from municipal wastewater by insolubilized laccase. Laccase from Trametes versicolor was aggregated by three-phase partitioning technique followed by cross-linking with glutaraldehyde to produce insolubilized laccase….

Energy & fatigue

Medium relevance

Reishi · 2022 · Journal Article · Frontiers in oncology

Integrated Whole-Transcriptome Profiling and Bioinformatics Analysis of the Polypharmacological Effects of Ganoderic Acid Me in Colorectal Cancer Treatment.

Ganoderic acid Me (GA-Me) is a natural bioactive compound derived from Ganoderma lucidum. Our present results suggested that GA-Me inhibited proliferation, induced DNA fragmentation and significantly activated caspase-9 and caspase-3 in HCT116 cells..

OncologyImmune support

Medium relevance

Turkey Tail · 2022 · Research Article · Plants (Basel, Switzerland)

Investigations on Fungi Isolated from Apple Trees with Die-Back Symptoms from Basilicata Region (Southern Italy).

Val d'Agri is an important orchard area located in the Basilicata Region (Southern Italy). A phenomenon affecting cv.

Medium relevance

Oyster Mushroom · 2022 · Journal Article · Frontiers in microbiology

Investigations on the Fusants From Wide Cross Between White-Rot Fungi and Saccharomyces cerevisiae Reveal Unknown Lignin Degradation Mechanism.

The degradation of lignocellulose by fungi, especially white-rot fungi, contributes a lot to carbon cycle, bio-fuel production, and many other bio-based applications..

Medium relevance

Oyster Mushroom · 2022 · Journal Article · Environmental technology

Iron-enriched mycelia of edible and medicinal basidiomycetes.

Iron bioaccumulation in basidiomycetes is an alternative to recover ferrous sulphate from titanium dioxide pigment production and to produce an iron-enriched mycelial biomass..

Medium relevance

Turkey Tail · 2022 · Research Article · Brazilian journal of microbiology: [publication of the Brazilian Society for Microbiology]

Isolation and characterization of wood-decomposing basidiomycetes from the Andean Forest in Boyacá, Colombia.

This study explores the biotechnological potential of lignocellulolytic fungi collected in an oak forest. Fungal collections were obtained from natural reserves located in Boyacá-Colombia, ranging from 2700 to 3000 m.a.s.l..

Medium relevance

Zhu Ling · 2022 · Research Article · Frontiers in microbiology

Isolation, genomic characterization, and mushroom growth-promoting effect of the first fungus-derived Rhizobium.

Polyporus umbellatus is a well-known edible and medicinal mushroom, and some bacteria isolated from mushroom sclerotia may have beneficial effects on their host. These mushroom growth-promoting bacteria (MGPBs) are of great significance in the mushroom production..

Medium relevance

Turkey Tail · 2022 · Journal Article · Bioelectrochemistry (Amsterdam, Netherlands)

Laccase bioconjugate and multi-walled carbon nanotubes-based biosensor for bisphenol A analysis.

Bisphenol A (BPA) is an endocrine disruptor compound that has been detected in aquatic ecosystems. In this work, the development of an electrochemical biosensor for BPA determination based on laccase from Trametes versicolor is reported..

Energy & fatigue

Medium relevance

Turkey Tail · 2022 · Journal Article · Environmental technology

Laccase immobilized on amino-functionalized magnetic Fe3O4-SiO2 core-shell material for 2,4-dichlorophenol removal.

In this study, an amino-functionalized magnetic silica microsphere material (Fe3O4-SiO2-NH2) was prepared. Using glutaraldehyde as a cross-linking agent, Trametes versicolor laccase was adsorbed-covalently bonded and immobilized on the material to prepare Laccase @ Fe3O4-SiO2..

Medium relevance

Turkey Tail · 2022 · Research Article · International journal of molecular sciences

Laccase Mediator Cocktail System as a Sustainable Skin Whitening Agent for Deep Eumelanin Decolorization.

The overproduction of eumelanin leads to a panel of unaesthetic hyper-pigmented skin diseases, including melasma and age spots. The treatment of these diseases often requires the use of tyrosinase inhibitors, which act as skin whitening agents by inhibiting the synthesis of eumelanin, with harmful side effects..

Skin & hydration

Medium relevance

Turkey Tail · 2022 · Research Article · Journal of functional biomaterials

Laccase-Carrying Polylactic Acid Electrospun Fibers, Advantages and Limitations in Bio-Oxidation of Amines and Alcohols.

Laccases are oxidative enzymes that could be good candidates for the functionalization of biopolymers with several applications as biosensors for the determination of bioactive amine and alcohols, for bioremediation of industrial wastewater, and for greener catalysts in oxidation reactions in organic synthesis,….

Medium relevance

Niu-Chang-Chih · 2022 · Research Article · Frontiers in cell and developmental biology

Large-scale transcriptomic analysis of coding and non-coding pathological biomarkers, associated with the tumor immune microenvironment of thyroid cancer and potential target therapy exploration.

Papillary thyroid carcinoma (PTC) is the most prevalent endocrine malignancy with a steadily increasing global incidence in recent decades. The pathogenesis of PTC is poorly understood, and the present diagnostic protocols are deficient..

OncologyImmune support

Medium relevance

Shiitake · 2022 · Journal Article · Molecular and cellular biochemistry

Lentinan triggers oxidative stress-mediated anti-inflammatory responses in lung cancer cells.

Inflammatory responses change several aspects of malignancies such as proliferation, survival, angiogenesis, and metastasis and lead to tumor progression. Lung cancer is the leading type of cancer worldwide and cancer-related inflammatory mediators challenge the successful treatments..

OncologyImmune supportEnergy & fatigueGut & microbiome

Medium relevance

Reishi · 2022 · Journal Article · Microbiology spectrum

Lignin Metabolism by Selected Fungi and Microbial Consortia for Plant Stimulation: Implications for Biologically Active Humus Genesis.

Plant lignin is regarded as an important source for soil humic substances (HSs). Nonetheless, it remains unclear whether microbial metabolism on lignin is related to the genesis of unique HS biological activities (e.g., direct plant stimulation)..

Energy & fatigue

Medium relevance

Reishi · 2022 · Journal Article · Food and chemical toxicology: an international journal published for the British Industrial Biological Research Association

Lucidenic acid A inhibits the binding of hACE2 receptor with spike protein to prevent SARS-CoV-2 invasion.

High infection caused by mutations of SARS-CoV-2 calls for new prevention strategy. Ganoderma lucidum known as a superior immunoenhancer exhibits various antiviral effects, whether it can resist SARS-CoV-2 remains unclear..

Immune supportRespiratory

Medium relevance

Reishi · 2022 · Journal Article · Bioprocess and biosystems engineering

Mechanism of enhanced production of triterpenoids in algal-fungal consortium.

Chlorella pyrenoidosa-Ganoderma lucidum symbiotic systems were constructed. The mechanism of enhanced production of triterpenoids in algal-fungal consortium by comparing the contents of triterpenoids in individual fungal systems and algal-fungal consortium systems was investigated..

Medium relevance

Cordyceps · 2022 · Journal Article · Frontiers in pharmacology

Medicinal Plants and Fungi Traditionally Used by Dulong People in Northwest Yunnan, China.

The Dulong, an ethnic group living in the isolated Northwest Yunnan of Southwest China, have directly used a wide of plants to serve their needs and have accumulated rich traditional knowledge about medicinal plants over years..

Immune support

Medium relevance

Oyster Mushroom · 2022 · Journal Article · mSphere

Metabolomics Highlights Different Life History Strategies of White and Brown Rot Wood-Degrading Fungi.

White and brown rot fungi efficiently deconstruct lignocellulose in wood, Earth's largest pool of aboveground biotic carbon and an important natural resource. Despite its vital importance, little is known about the metabolomic signatures among fungal species and nutritional modes (rot types)..

Metabolic health

Medium relevance

Oyster Mushroom · 2022 · Journal Article · Journal of hazardous materials

Microbially-mediated synthesis of activated carbon derived from cottonseed husks for enhanced sulfanilamide removal.

This study provided a novel pathway to develop activated carbon with enhanced adsorption performance via feedstock pretreatment by fungi. The growth of Pleurotus ostreatus on cottonseed husks offered this feedstock an advantageous pore size for porous carbon making..

Energy & fatigue

Medium relevance

Reishi · 2022 · Journal Article · Molecules (Basel, Switzerland)

Mushroom-Derived Novel Selenium Nanocomposites' Effects on Potato Plant Growth and Tuber Germination.

Multicomponent materials, where nanosized selenium (Se) is dispersed in polymer matrices, present as polymer nanocomposites (NCs), namely, selenium polymer nanocomposites (SeNCs). Selenium as an inorganic nanofiller in NCs has been extensively studied for its biological activity..

Immune supportEnergy & fatigue

Medium relevance

Chaga · 2022 · Journal Article · Food & function

Neuroprotective effects of a new triterpenoid from edible mushroom on oxidative stress and apoptosis through the BDNF/TrkB/ERK/CREB and Nrf2 signaling pathway in vitro and in vivo.

Inonotus obliquus (Fr.) Pilat is an edible mushroom which is used to produce tea and syrup due to its medicinal properties. In this study, 10 secondary metabolites (1-10), including a new lanostane triterpenoid named 2α-hydroxy-inotodiol (2α-HI, 1), were identified from the edible mushroom I..

OncologyCognition & nervesEnergy & fatigue

Medium relevance

Reishi · 2022 · Journal Article · Biology

Novel Glycosylation by Amylosucrase to Produce Glycoside Anomers.

Glycosylation occurring at either lipids, proteins, or sugars plays important roles in many biological systems. In nature, enzymatic glycosylation is the formation of a glycosidic bond between the anomeric carbon of the donor sugar and the functional group of the sugar acceptor..

Energy & fatigue

Medium relevance

Turkey Tail · 2022 · Journal Article · Colloids and surfaces. B, Biointerfaces

Novel laccase from Xylaria polymorpha and its efficiency in the biotransformation of pharmaceuticals: Optimization of operational conditions, comparative effect of redox-mediators and toxicity studies.

The promising potentials of biocatalytic treatment processes in the removal of micropollutants whilst eliminating health and environmental hazards have attracted great attention in recent years..

Energy & fatigueMetabolic health

Medium relevance

Reishi · 2022 · Journal Article · Frontiers in pharmacology

Polysaccharides, Next Potential Agent for the Treatment of Epilepsy?

Epilepsy is a chronic neurological disorder. Current pharmacological therapies for epilepsy have limited efficacy that result in refractory epilepsy (RE).

Immune supportCognition & nervesGut & microbiome