MycoData

Cordyceps · 2022 · Journal Article · Frontiers in microbiology

Development of Cordyceps javanica BE01 with enhanced virulence against Hyphantria cunea using polyethylene glycol-mediated protoplast transformation.

Cordyceps javanica has promising application prospects as an entomopathogenic fungus with a wide range of hosts. To enhance the virulence of C.

Immune supportEnergy & fatigueGut & microbiome

Cordyceps · 2022 · Journal Article · Frontiers in veterinary science

Effects of Coated Sodium Butyrate and Polysaccharides From Cordyceps cicadae on Intestinal Tissue Morphology and Ileal Microbiome of Squabs.

This experiment was conducted to investigate the effects of dietary supplementation with different levels of coated sodium butyrate (CSB) and polysaccharides extracted from Cordyceps cicadae (CCP) on growth performance, intestinal tissue morphology and ileum microbiome in squabs..

Maitake · 2022 · Journal Article · International journal of biological macromolecules

Fermentability of Maitake polysaccharides processed by various hydrothermal conditions and fermented with probiotic (Lactobacillus).

Maitake polysaccharides, after hydrothermal processing, were fermented with Lactobacillus acidophilus CCFM202 (L.A.) and Lactobacillus plantarum CCFM6392 (L.P.). The degradation of molecular weight of polysaccharides by hydrothermal processing under acidic conditions was obviously enhanced, which turned part of the….

Cordyceps · 2021 · Journal Article · Food & function

A polysaccharide from natural Cordyceps sinensis regulates the intestinal immunity and gut microbiota in mice with cyclophosphamide-induced intestinal injury.

A polysaccharide from Cordyceps sinensis (NCSP) was reported to attenuate intestinal injury and regulate the balance of T helper (Th)1/Th2 cells in immunosuppressed mice. However, whether it influences Th17 and regulatory T (Treg) cells as well as gut ecology remains unknown..

Cordyceps · 2021 · Journal Article · Evidence-based complementary and alternative medicine: eCAM

Arsenic Content, Speciation, and Distribution in Wild Cordyceps sinensis.

The excessive arsenic content in wild Cordyceps sinensis has caused great concerns on human health. The toxicity of arsenic depends on its concentration, chemical form, and valence.

Cordyceps · 2021 · Journal Article · Insects

Field Efficacy of Cordyceps javanica, White Oil and Spinetoram for the Management of the Asian Citrus Psyllid, Diaphorina citri.

Citrus greening disease is devastating the citrus industry in Florida, and the conventional synthetic pesticide applications used to control the vector, the Asian citrus psyllid (AsCP), Diaphorina citri, are rapidly becoming unsustainable..

Cordyceps · 2021 · Journal Article · Microorganisms

In Planta Localization of Endophytic Cordyceps fumosorosea in Carrizo Citrus.

Entomopathogenic fungi can be a useful resource for controlling insect vectors of citrus plant pathogens, such as the Asian citrus psyllid (Diaphorina citri) associated with huanglongbing or the citrus root weevil (Diaprepes abbreviatus) associated with the spread of Phytophtora spp..

Immune supportGut & microbiomeLiver support

Oyster Mushroom · 2021 · Journal Article · Journal of agricultural and food chemistry

Influence of a Biotechnologically Produced Oyster Mushroom (Pleurotus sajor-caju) on the Gut Microbiota and Microbial Metabolites in Obese Zucker Rats.

Mushrooms are a rich source of dietary fiber. This study aimed to characterize the modulation of colonic microbiota in Zucker rats after supplementing their diet with a biotechnologically produced oyster mushroom (Pleurotus sajor-caju)..

Cordyceps · 2021 · Journal Article · Insects

Unraveling the Mode of Action of Cordyceps fumosorosea: Potential Biocontrol Agent against Plutella xylostella (Lepidoptera: Plutellidae).

The entomopathogenic fungus, Cordyceps fumosorosea is a potential eco-friendly biocontrol agent. The present study revealed the entire course of infection of P.

OncologyMetabolic healthGut & microbiome

Almond Mushroom · 2020 · Randomized Controlled Trial · International journal of radiation oncology, biology, physics

A Multi-atlas Approach for Active Bone Marrow Sparing Radiation Therapy: Implementation in the NRG-GY006 Trial.

PURPOSE: Sparing active bone marrow (ABM) can reduce acute hematologic toxicity in patients undergoing chemoradiotherapy for cervical cancer, but ABM segmentation based on positron emission tomography/computed tomography (PET/CT) is costly..

Cordyceps · 2017 · Research Support, Non U.S. Gov'T · Scientific reports

Fungus-larva relation in the formation of Cordyceps sinensis as revealed by stable carbon isotope analysis.

For more than one thousand years, Cordyceps sinensis has been revered as a unique halidom in the Qinghai-Tibetan Plateau for its mysterious life history and predominant medicinal values..

OncologyImmune supportMetabolic healthGut & microbiome

Maitake · 2009 · Journal Article · International immunopharmacology

Maitake beta-glucan enhances therapeutic effect and reduces myelosupression and nephrotoxicity of cisplatin in mice.

Cisplatin is broadly used clinically as an anticancer drug. Despite its significant anticancer activity, cisplatin-induced nephrotoxicity and myelosuppression limit its use..

Cordyceps · 2026 · Research Article · Drug design, development and therapy

Cordycepin Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice by Inhibiting IL-6/IL-6R-Mediated p38 MAPK and NF-κB Activation Through Adenosine A2A Receptor Stimulation.

BACKGROUND: Current ulcerative colitis (UC) therapies often cause adverse effects, and novel treatments are urgently needed. Cordycepin (COR), a bioactive compound from Cordyceps militaris, shows anti-inflammatory and intestinal protective potential, its precise role and mechanisms in UC remain unclear..

Metabolic healthGut & microbiome

Cordyceps · 2026 · Journal Article · Food research international (Ottawa, Ont.)

Cordycepin-mediated protection against bisphenol A-induced male reproductive toxicity via PI3K/mTOR/HIF-1α signaling.

Environmental endocrine disruptors, such as bisphenol A (BPA), pose significant threats to male reproductive health. Cordycepin, a bioactive nucleoside derived from Cordyceps militaris, has demonstrated antioxidant and bioregulatory effects; however, its protective role against BPA-induced reproductive toxicity….

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

Cordyceps · 2026 · Journal Article · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Elucidation of mechanisms underlying the therapeutic effects of cordycepin on pulmonary hypertension, with a focus on cell senescence and gut microbiota.

INTRODUCTION: Pulmonary hypertension (PH) is a progressive cardiopulmonary disorder characterized by excessive pulmonary vascular remodeling and aberrant proliferation of pulmonary artery smooth muscle cells (PASMCs). Emerging evidence suggests that gut microbiota dysbiosis contributes to PH development..

Energy & fatigueGut & microbiome

Oyster Mushroom · 2026 · Journal Article · Journal of environmental management

Feasibility of soilless substrate systems supplemented with black soldier fly frass for sustainable mushroom cultivation.

The rising cost and limited availability of sawdust have driven interest in alternative substrates for mushroom cultivation. Black soldier fly larvae (BSFL) frass is a nutrient-rich byproduct of insect farming that could serve as a low-cost supplement, however, its effective incorporation requires a suitable substrate….

Immune supportGut & microbiomeRespiratory

Reishi · 2026 · Research Article · Chinese medicine

Guominkang formula alleviates airway inflammation in HDM-induced asthma mice by regulating Wnt/β-Catenin pathway.

BACKGROUND: The Guominkang formula (GMK), formulated according to the principle of "treatment based on constitution differentiation," comprises Prunus mume (Siebold) Siebold & Zucc. (Wumei), Saposhnikovia divaricata (Turcz.

Cordyceps · 2026 · Research Article · Toxics

Integrating Speciation Analysis and Bioaccessibility to Reassess Cadmium Exposure Risk from Six Mushrooms.

Accurate assessment of dietary exposure to cadmium in mushrooms is crucial for food safety. The inherent limitation lies in relying solely on total cadmium content, failing to reflect its actual bioaccessibility.

King Oyster · 2026 · Journal Article · Innovative Food Science and Emerging Technologies

Mycelial growth stimulus-responsive 4D printing: A novel approach for mycelium-based meat analogs fabrication

Mycelium emerges as a promising sustainable biomaterial for meat analogs, owing to its fibrous structure and rich nutritional profile. This study introduces a novel 4D printing approach that leverages mycelial growth as a biological stimulus to fabricate mycelium-based meat analogs..

Cordyceps · 2026 · Journal Article · International journal of biological macromolecules

Physicochemical, structural, digestive stability, and microbiota effects of five edible mushroom polysaccharides (EMPs).

EMPs are widely used for their food-medicine characteristics and bioactivities. However, the lack of unified standards has resulted in inconsistent product quality..

Cordyceps · 2026 · Journal Article · Current microbiology

Selective Carbohydrate Modulation Enhances BLIS-Mediated Bioprotection Against Multidrug-Resistant Foodborne Pathogens During Vegetable Fermentation.

Lactic acid bacteria (LAB) play a pivotal role in food fermentation by shaping microbial ecosystems and enhancing product safety through the production of antimicrobial metabolites..

Cordyceps · 2025 · Research Article · Foods (Basel, Switzerland)

Bioactive Polysaccharides Prevent Lipopolysaccharide-Induced Intestinal Inflammation via Immunomodulation, Antioxidant Activity, and Microbiota Regulation.

Intestinal inflammation involves barrier impairment, immune hyperactivation, and oxidative stress imbalance. Bioactive polysaccharides universally alleviate inflammation via anti-inflammatory, antioxidant, and microbiota-modulating effects, yet exhibit distinct core mechanisms..

King Oyster · 2025 · Research Article · Journal of animal physiology and animal nutrition

Conversion of Lignocellulosic Biomass Into Valuable Feed for Ruminants Using White Rot Fungi.

White rot fungi can degrade lignin and improve the nutritional value of highly lignified biomass for ruminants. We screened for excellent fungi-biomass combinations by investigating the improvement of digestibility of wheat straw, barley straw, oat straw, rapeseed straw, miscanthus, new reed, spent reed from thatched….

Immune supportCognition & nervesEnergy & fatigueGut & microbiome

Cordyceps · 2025 · Journal Article · Molecular neurobiology

Cordycepin Mitigates Sepsis-Associated Encephalopathy by Promoting Microglial M2 Polarization via the IL-17a/IL-17RA/NF-κB Axis.

Sepsis-associated encephalopathy (SAE) is a serious neurological complication of systemic infection, marked by cognitive deficits, neuroinflammation, and increased mortality. Microglial activation and proinflammatory signaling pathways, particularly involving IL-17a and NF-κB, are key contributors to SAE pathogenesis..

Cordyceps · 2025 · Journal Article · International Journal of Biological Macromolecules

Editing a mushroom with high-digestibility using a novel endo-N-acetyl-β-D-glucosaminidase

Fungi comprise approximately 2 % of the Earth's biomass; however, the human gastrointestinal tract has a limited capacity to digest fungal biomass. In this study, a novel endo-N-acetyl-β-D-glucosaminidase, Endo CM, was characterized in the mushroom-forming fungus Cordyceps militaris, where it plays a role in….

Cordyceps · 2025 · Journal Article · International journal of biological macromolecules

Editing a mushroom with high-digestibility using a novel endo-N-acetyl-β-D-glucosaminidase.

Shiitake · 2025 · Journal Article · Industrial crops and products

Mild thermal treatment assists fungal preprocessing of softwood sawdust for production of fermentable sugar

Preheating with hot air at 85 – 125 °C was evaluated for its effectiveness in removing terpenes and terpenoids in softwood sawdust, thereby enhancing fungal preprocessing and subsequent saccharification of softwood-based mushroom substrates. Sawdust from pine (Pinus sylvestris L.) and spruce (Picea abies (L.) H..

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

Reishi · 2025 · Journal Article · Food Research International

Study on the intervention mechanism of Ganodermalucidum polysaccharides in mice with atopic dermatitis

Taishan Red Reishi Mushroom, also known as Taishan Ganoderma lucidum, is a medicinal and edible mushroom. Polysaccharides from Taishan Ganodermalucidum (GLP) represent its most significant bioactive component..

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

Reishi · 2025 · Journal Article · Food research international (Ottawa, Ont.)

Study on the intervention mechanism of Ganodermalucidum polysaccharides in mice with atopic dermatitis.

King Oyster · 2025 · Journal Article · Food Chemistry

Successive fungal solid-state fermentation and UV-B irradiation: A novel strategy to boost bioactive potential and vitamin D2 levels of corn flour

This study introduces a novel biofortification strategy that combines solid-state fermentation (SSF) using edible fungi Pleurotus eryngii and Hericium erinaceus, followed by UV-B irradiation of colonized corn flour, to enhance its vitamin D₂ content and functional properties..

Cordyceps · 2024 · Research Article · International journal of molecular sciences

Translation of Mutant Repetitive Genomic Sequences in Hirsutella sinensis and Changes in the Secondary Structures and Functional Specifications of the Encoded Proteins.

Multiple repetitive sequences of authentic genes commonly exist in fungal genomes. AT-biased genotypes of Ophiocordyceps sinensis have been hypothesized as repetitive pseudogenes in the genome of Hirsutella sinensis (GC-biased Genotype #1 of O..

Immune supportGut & microbiomeRespiratory

Shiitake · 2021 · Randomized Controlled Trial · Nutrients

Adjuvant Effect of Orally Applied Preparations Containing Non-Digestible Polysaccharides on Influenza Vaccination in Healthy Seniors: A Double-Blind, Randomised, Controlled Pilot Trial.

Senior individuals can suffer from immunosenescence and novel strategies to bolster the immune response could contribute to healthy ageing. In this double-blind, randomised, controlled pilot trial, we investigated the ability of non-digestible polysaccharide (NPS) preparations to enhance the immune response in a human….

Snow Fungus · 1993 · Review · Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]

[Pseudomonas contamination of Chinese herbal drug. Tremella fuciformis].

Metadata-grounded summary: This review indexes research on Tremella fuciformis in Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] in 1993. MycoData maps the paper to gut & microbiome, skin & hydration based on its title, species context, article metadata, and study classification..

Energy & fatigueMetabolic healthGut & microbiome

Turkey Tail · 2025 · Research Support, Non U.S. Gov'T · Applied and environmental microbiology

Fungus-mediated bacterial survival and migration enhance wood lignin degradation.

UNLABELLED: Bacterial-fungal interactions are increasingly recognized as a key factor in wood decomposition; however, the specific mechanisms underlying these interactions remain unclear..

Immune supportEnergy & fatigueGut & microbiome

Reishi · 2022 · Journal Article · Frontiers in nutrition

Insoluble Dietary Fibers From By-Products of Edible Fungi Industry: Basic Structure, Physicochemical Properties, and Their Effects on Energy Intake.

With the rapid development of the edible fungi industry in the world, especially in China, the resource utilization of edible fungi by-products has become an urgent problem for the industry's sustainable development..

Immune supportMetabolic healthGut & microbiome

Cordyceps · 2026 · Journal Article · Phytomedicine: international journal of phytotherapy and phytopharmacology

Cordyceps cicadae polysaccharides ameliorate ulcerative colitis by modulating the gut microbiota and regulating the bile acid/FXR/NF-κB signaling pathway.

BACKGROUND: Ulcerative colitis (UC) is a chronic, relapsing inflammatory bowel disease, closely linked to dysbiosis of the intestinal microbiota and abnormal bile acid homeostasis. Polysaccharides derived from Paecilomyces cicadae (CCP) exhibit immunomodulatory and anti-inflammatory effects..

Shiitake · 2025 · Journal Article · Journal of the Japanese Forest Society

Estimation of the Amount of 137Cs Transferred into the Fruiting Bodies Considering Distribution of That of Shiitake Mushroom Logs

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in Journal of the Japanese Forest Society in 2025. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

Shiitake · 2025 · Journal Article · Mushroom Science and Biotechnology

Fruiting body yield of shiitake mushrooms cultivated on partially debarked logs

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in Mushroom Science and Biotechnology in 2025. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

Snow Fungus · 2025 · Journal Article · Abstracts of Papers Presented at the Meeting of the Mycological Society of Japan

Search for antifungal compounds against Cryptococcus neoformans from fungi isolated from snow fungus

Metadata-grounded summary: This journal article indexes research on Tremella fuciformis in Abstracts of Papers Presented at the Meeting of the Mycological Society of Japan in 2025. MycoData maps the paper to gut & microbiome, skin & hydration based on its title, species context, article metadata, and study classification..

Shiitake · 2024 · Journal Article · Mushroom Science and Biotechnology

Effect of sound and sound frequency associated with lightning strikes on the promotion of fruiting body development in shiitake mushrooms

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in Mushroom Science and Biotechnology in 2024. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

Immune supportMetabolic healthGut & microbiome

Cordyceps · 2024 · Journal Article · Food & function

Soluble dietary fibers from solid-state fermentation of wheat bran by the fungus Cordyceps cicadae and their effects on colitis mice.

Ulcerative colitis is a chronic inflammatory disease with a complex pathogenesis for which there is no definitive therapeutic agent. Fermentation, as a green and efficient bioprocessing technique, has been shown to enhance the biological activity of food ingredients..

Shiitake · 2024 · Journal Article · Food Science and Technology Research

Structural analysis of vacuum microwave dried shiitake mushrooms based on X-ray CT images and physical properties

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in Food Science and Technology Research in 2024. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

Reishi · 2023 · Systematic Review · Nutrients

Changes in the Gut Microbiota after the Use of Herbal Medicines in Overweight and Obese Individuals: A Systematic Review.

BACKGROUND: Herbal medicine is a low-cost treatment and has been increasingly applied in obesity treatment. Gut microbiota (GM) is strongly associated with obesity pathogenesis..

Oyster Mushroom · 2021 · Research Support, Non U.S. Gov'T · PloS one

Cultivating oyster mushrooms on red grape pomace waste enhances potential nutritional value of the spent substrate for ruminants.

The use of red grape pomace (GP; Vitis vinifera L. var.

Shiitake · 2020 · Published Erratum · Biological trace element research

Correction to: Lentinula edodes as a Source of Bioelements Released Into Artificial Digestive Juices and Potential Anti-inflammatory Material.

The original version of this article unfortunately contained a mistake..

Shiitake · 2015 · Journal Article · The Japanese Forest Society Congress

Effects of resting stage in high temperature on fruit body development of Lentinula edodes with bed logs

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in The Japanese Forest Society Congress in 2015. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

Shiitake · 2015 · Journal Article · Food & function

Lentinula edodes-derived polysaccharide rejuvenates mice in terms of immune responses and gut microbiota.

Aging is characterized by impaired immunity and unbalanced gut microbiota. Prebiotics have the capability to prevent or reverse age-related declines in health by modulating gut microbiota.

Shiitake · 2015 · Journal Article · The Japanese Forest Society Congress

Radiocesium concentration in bed-logs of Lentinula edodes, moved to bed-log laying yard

Yellow Morel · 2015 · Journal Article · International journal of surgical pathology

The Morchella esculenta of the digestive tract.

Metadata-grounded summary: This journal article indexes research on Morchella esculenta in International journal of surgical pathology in 2015. MycoData maps the paper to gut & microbiome based on its title, species context, article metadata, and study classification..