MycoData
Medicinal fungi research database
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Oncology
Cancer, tumor biology, chemotherapy support, and oncology adjunct literature.
Species records
Species record
Oyster Mushroom
Pleurotus ostreatus
- Studies
- 1,947
- Avg relevance
- 53
- Latest
- 2026
Species record
Reishi · Lingzhi
Ganoderma lucidum
- Studies
- 1,830
- Avg relevance
- 60
- Latest
- 2026
Species record
Turkey Tail · Yun Zhi
Trametes versicolor
- Studies
- 1,828
- Avg relevance
- 41
- Latest
- 2026
Species record
Shiitake · Hua Gu
Lentinula edodes
- Studies
- 1,766
- Avg relevance
- 60
- Latest
- 2026
Species record
Cordyceps · Scarlet Club
Cordyceps militaris
- Studies
- 1,635
- Avg relevance
- 67
- Latest
- 2026
Species record
Cordyceps · Caterpillar Fungus
Ophiocordyceps sinensis
- Studies
- 1,576
- Avg relevance
- 59
- Latest
- 2026
Species record
Almond Mushroom · ABM
Agaricus blazei
- Studies
- 1,441
- Avg relevance
- 54
- Latest
- 2026
Species record
Enoki · Winter Mushroom
Flammulina velutipes
- Studies
- 1,403
- Avg relevance
- 47
- Latest
- 2026
Species record
King Oyster · Eryngii
Pleurotus eryngii
- Studies
- 1,278
- Avg relevance
- 60
- Latest
- 2026
Species record
Maitake · Hen of the Woods
Grifola frondosa
- Studies
- 1,276
- Avg relevance
- 48
- Latest
- 2026
Species record
Snow Fungus · Silver Ear
Tremella fuciformis
- Studies
- 1,052
- Avg relevance
- 29
- Latest
- 2026
Species record
Lion's Mane · Yamabushitake
Hericium erinaceus
- Studies
- 862
- Avg relevance
- 67
- Latest
- 2026
Species record
Chaga
Inonotus obliquus
- Studies
- 738
- Avg relevance
- 65
- Latest
- 2026
Species record
Mesima · Sanghwang
Phellinus linteus
- Studies
- 722
- Avg relevance
- 58
- Latest
- 2026
Species record
Niu-Chang-Chih
Antrodia camphorata
- Studies
- 496
- Avg relevance
- 63
- Latest
- 2026
Species record
Nameko · Nametake
Pholiota microspora
- Studies
- 421
- Avg relevance
- 29
- Latest
- 2026
Species record
Yellow Morel
Morchella esculenta
- Studies
- 392
- Avg relevance
- 42
- Latest
- 2026
Species record
Zhu Ling · Umbrella Polypore
Polyporus umbellatus
- Studies
- 263
- Avg relevance
- 55
- Latest
- 2026
Species record
Wood Ear · Kikurage
Auricularia auricula-judae
- Studies
- 254
- Avg relevance
- 51
- Latest
- 2026
Species record
Agarikon · Quinine Conk
Fomitopsis officinalis
- Studies
- 47
- Avg relevance
- 55
- Latest
- 2026
Articles
4,056 results
Showing 1,301–1,350 of 4,056
Reishi · 1984 · Journal Article · Nippon Nōgeikagaku Kaishi
Fractionation, Structural Features and Antitumor Activity of Water-Soluble Polysaccharide from “Reishi, ” the Fruit Body of Ganoderma lucidum
Metadata-grounded summary: This journal article indexes research on Ganoderma lucidum in Nippon Nōgeikagaku Kaishi in 1984. MycoData maps the paper to oncology, immune support based on its title, species context, article metadata, and study classification..
Reishi · 1984 · Journal Article · Agricultural and Biological Chemistry
New Bitter C27 and C30 Terpenoids from the Fungus Ganoderma lucidum (Reishi)
Metadata-grounded summary: This journal article indexes research on Ganoderma lucidum in Agricultural and Biological Chemistry in 1984. MycoData maps the paper to oncology, immune support, metabolic health, liver support based on its title, species context, article metadata, and study classification..
Cordyceps · 2017 · Journal Article · Tumour biology: the journal of the International Society for Oncodevelopmental Biology and Medicine
Cordycepin induces apoptosis in human bladder cancer cells via activation of A3 adenosine receptors.
Bladder cancer is a neoplasm originated from bladder epithelial cells. The therapy for bladder cancer is so far not satisfactory.
Reishi · 2019 · Review · Advances in experimental medicine and biology
Preventive and Therapeutic Effect of Ganoderma (Lingzhi) on Liver Injury.
Ganoderma lucidum (G. lucidum, Lingzhi) has a wide range of hepatoprotective effects.
Turkey Tail · 2012 · Case Reports · Global advances in health and medicine
Trametes versicolor (Turkey Tail Mushrooms) and the Treatment of Breast Cancer.
Metadata-grounded summary: This case reports indexes research on Trametes versicolor in Global advances in health and medicine in 2012. MycoData maps the paper to oncology based on its title, species context, article metadata, and study classification..
Maitake · 2002 · Review · Alternative medicine review: a journal of clinical therapeutic
Can maitake MD-fraction aid cancer patients?
Maitake mushroom (Grifola frondosa) MD-fraction containing beta-1,6 glucan with beta-1,3 branched chains has previously exhibited strong anticancer activity by increasing immune-competent cell activity.1,2 In this non-random case series, a combination of MD-fraction and whole maitake powder was investigated to….
Maitake · 2001 · Review · Alternative medicine review: a journal of clinical therapeutic
Maitake extracts and their therapeutic potential.
Maitake (Grifola frondosa) is the Japanese name for an edible fungus with a large fruiting body characterized by overlapping caps. It is a premier culinary as well as medicinal mushroom.
Reishi · 2026 · Retraction Of Publication · Scientific reports
Retraction Note: The effect of Ganoderma lucidum polysaccharide extract on sensitizing prostate cancer cells to flutamide and docetaxel: an in vitro study.
Metadata-grounded summary: This retraction of publication indexes research on Ganoderma lucidum in Scientific reports in 2026. MycoData maps the paper to oncology, immune support based on its title, species context, article metadata, and study classification..
Reishi · 2026 · Retraction Of Publication · Integrative cancer therapies
Retraction: Ganoderma lucidum Exerts an Anticancer Effect on Human Osteosarcoma Cells via Suppressing the Wnt/β-Catenin Signaling Pathway.
Metadata-grounded summary: This retraction of publication indexes research on Ganoderma lucidum in Integrative cancer therapies in 2026. MycoData maps the paper to oncology based on its title, species context, article metadata, and study classification..
Snow Fungus · 2025 · Published Erratum · International journal of biological macromolecules
Corrigendum to "Cu-Tremella fuciformis polysaccharide-based tumor microenvironment-responsive injectable gels for cuproptosis-based synergistic osteosarcoma therapy" [Int. J. Biol. Macromol. 217 (2024): 132029].
Metadata-grounded summary: This published erratum indexes research on Tremella fuciformis in International journal of biological macromolecules in 2025. MycoData maps the paper to oncology, immune support based on its title, species context, article metadata, and study classification..
Niu-Chang-Chih · 2025 · Retraction Of Publication · Evidence-based complementary and alternative medicine: eCAM
RETRACTION: The Antitumor Activity of Antrodia camphorata in Melanoma Cells: Modulation of Wnt/β-Catenin Signaling Pathways.
[This retracts the article DOI: 10.1155/2012/197309.]..
Almond Mushroom · 2024 · Letter · Asian journal of surgery
Agaricus blazei Murill extract FA-2-b-β inhibits gastric cancer cell proliferation through the mechanisms of cell-cycle blocking and apoptosis by the mitochondrial pathway.
Metadata-grounded summary: This letter indexes research on Agaricus blazei in Asian journal of surgery in 2024. MycoData maps the paper to oncology, energy & fatigue based on its title, species context, article metadata, and study classification..
Reishi · 2024 · Published Erratum · Cancer cell international
Correction: Exploring the anti-cancer potential of Ganoderma Lucidum polysaccharides (GLPs) and their versatile role in enhancing drug delivery systems: a multifaceted approach to combat cancer.
Metadata-grounded summary: This published erratum indexes research on Ganoderma lucidum in Cancer cell international in 2024. MycoData maps the paper to oncology, immune support, liver support based on its title, species context, article metadata, and study classification..
Almond Mushroom · 2024 · Letter · Asian journal of surgery
Correlation of the apoptosis in the mitochondrial pathway with the JAK2/STAT3 signaling pathway regarding the effect of Agaricus blazei Murill extract FA-2-b-β in inhibiting the proliferation of gastric cancer cells.
Metadata-grounded summary: This letter indexes research on Agaricus blazei in Asian journal of surgery in 2024. MycoData maps the paper to oncology, energy & fatigue based on its title, species context, article metadata, and study classification..
Reishi · 2023 · Journal Article · International journal of biological macromolecules
A Ganoderma lucidum polysaccharide F31 alleviates hyperglycemia through kidney protection and adipocyte apoptosis.
In this paper, we reported an excellent hypoglycemic effect of a Ganoderma lucidium polysaccharide F31 with efficacies between 45 and 54 %, approaching to that of liraglutide (52 %). Significantly, F31 reduced the body weight gains and food intakes..
Mesima · 2023 · Research Article · BMC complementary medicine and therapies
Effect of Smilax spp. and Phellinus linteus combination on cytotoxicity and cell proliferation of breast cancer cells.
BACKGROUND: Although the prevalence of breast cancer (BC) has been reduced in recent years, proficient therapeutic regimens should be further investigated with the aim of further reducing the mortality rate..
Niu-Chang-Chih · 2023 · Research Article · Molecules (Basel, Switzerland)
Ergosterol Isolated from Antrodia camphorata Suppresses LPS-Induced Neuroinflammatory Responses in Microglia Cells and ICR Mice.
Inflammation caused by microglial activation is important in neurodegenerative diseases. In this research, we tried to identify safe and effective anti-neuroinflammatory agents by screening a natural compounds library and found that Ergosterol can inhibit the nuclear factor kappa-light-chain enhancer of the activated….
Reishi · 2023 · Journal Article · Journal of primary health care
Ganoderma lucidum.
Metadata-grounded summary: This journal article indexes research on Ganoderma lucidum in Journal of primary health care in 2023. MycoData maps the paper to oncology, immune support, metabolic health, liver support based on its title, species context, article metadata, and study classification..
Maitake · 2023 · Preprint · journal metadata
Influence of Dried Maitake and Enoki Mushroom Addition on Antioxidant, Potentially Anti-inflammatory, and Anti-cancer Properties of Enriched Pasta
The influence of the addition of 2.5, 5, 7.5, and 10.0% of dried Enoki and Maitake mushrooms on the content of bioactive compounds and some pro-health properties of pasta was studied..
Zhu Ling · 2023 · Journal Article · International journal of biological macromolecules
Polyporus umbellatus polysaccharide iron-based nanocomposite for synergistic M1 polarization of TAMs and combinational anti-breast cancer therapy.
M1 polarization of tumor-associated macrophages (TAMs) is a promising approach to breaking through therapeutic barriers imposed by the immunosuppressive tumor microenvironment (TME)..
Maitake · 2023 · Journal Article · International journal of biological macromolecules
Preparation and structural characterization of acid-extracted polysaccharide from Grifola frondosa and antitumor activity on S180 tumor-bearing mice.
In this study, an acid-extracted polysaccharide (GFP-A) was extracted from the fruiting bodies of G. frondosa with 1 % hydrochloric acid solution.
Chaga · 2023 · Preprint · journal metadata
Protective Effects of Lanostane Triterpenoids from Chaga Mushroom in Human Keratinocytes HaCaT Cell against Inflammatory and Oxidative Stresses
Inotodiol, a lanostane-type triterpenoid, and many phytochemicals from Chaga mushroom have been investigated for various allergic diseases. However, antiaging and anti-inflammatory activities of inotodiol under different types of oxidative stress and impact of inotodiol on collagen and hyaluronan synthesis are not….
Turkey Tail · 2022 · Journal Article · Lignin
4-Hydroxybenzoic Acid Secreted from Trametes versicolor Catalyzes the Oxidation of a Nonphenolic β-O-4 Lignin Model Dimer as Laccase Mediator
Metadata-grounded summary: This journal article indexes research on Trametes versicolor in Lignin in 2022. MycoData maps the paper to oncology, immune support based on its title, species context, article metadata, and study classification..
Chaga · 2022 · Journal Article · Parasitology international
Anti-malarial activity in a Chinese herbal supplement containing Inonotus obliquus and Panax notoginseng.
Plasmodium falciparum, the most virulent human malaria parasite, causes serious diseases among the infected patients in the world and is particularly important in African regions. Although artemisinin combination therapy is recommended by the WHO for treatment of P..
Turkey Tail · 2022 · Journal Article · Chemosphere
Catalyzed degradation of polycyclic aromatic hydrocarbons by recoverable magnetic chitosan immobilized laccase from Trametes versicolor.
The capability of laccase to oxidate a broad range of polyphenols and aromatic substrates in vitro offers a new technological option for the remediation of polycyclic aromatic hydrocarbon (PAH) pollution with high cytotoxicity..
Maitake · 2022 · Preprint · journal metadata
Cd3 Epsilon Immune Restorative Ability Induced by Maitake Pro4x in Immunosupressed Balbc Mice.
Abstract Objectives: The aim of this research was to determine if the rich beta glucan compound called Maitake Pro4X can recover the T cell/NK population depleted by Dexamethasone treatment in lymph nodes from cancer-free BALBc female mice..
Turkey Tail · 2022 · Journal Article · Mushroom Science and Biotechnology
Development of fermented tofu with mushroom koji from Trametes versicolor mycelium
Metadata-grounded summary: This journal article indexes research on Trametes versicolor in Mushroom Science and Biotechnology in 2022. MycoData maps the paper to oncology, immune support based on its title, species context, article metadata, and study classification..
Reishi · 2022 · Journal Article · Mushroom Science and Biotechnology
Identification, characterization and expression of a glutamic protease gene from Ganoderma lucidum
Metadata-grounded summary: This journal article indexes research on Ganoderma lucidum in Mushroom Science and Biotechnology in 2022. MycoData maps the paper to oncology, immune support, metabolic health, liver support based on its title, species context, article metadata, and study classification..
Shiitake · 2022 · Research Article · Infection and drug resistance
In vitro Anti SARS-CoV-2 Activity and Docking Analysis of Pleurotus ostreatus, Lentinula edodes and Agaricus bisporus Edible Mushrooms.
BACKGROUND: Fungi are rich source of biologically active metabolites aimed for the improvement of human health through the prevention of various diseases, including infections and inflammatory disorders..
Wood Ear · 2022 · Journal Article · Trends in food science & technology
Insights into health-promoting effects of Jew's ear (Auricularia auricula-judae)
Jew's ear is an important cultivated edible mushroom. It contains high levels of melanin, carbohydrates, fiber, protein, amino acids, ergosterol, and ascorbic acids, and a very lower level of fat.
Chaga · 2021 · Research Article · Plants (Basel, Switzerland)
A Novel Bioanalytical Method for Determination of Inotodiol Isolated from Inonotus Obliquus and Its Application to Pharmacokinetic Study.
In this study, we developed a bioanalytical method using liquid chromatography coupled to triple quadrupole tandem mass spectrometry (LC-MS/MS) to apply to a pharmacokinetic study of inotodiol, which is known for its anti-cancer activity..
Reishi · 2021 · Journal Article · Mushroom Science and Biotechnology
Cultivation of Ganoderma lucidum and G. sinense on medium containing bamboo chips
Metadata-grounded summary: This journal article indexes research on Ganoderma lucidum in Mushroom Science and Biotechnology in 2021. MycoData maps the paper to oncology, immune support, metabolic health, liver support based on its title, species context, article metadata, and study classification..
Niu-Chang-Chih · 2020 · Research Support, Non U.S. Gov'T · Journal of natural products
Antcamphorols A-K, Cytotoxic and ROS Scavenging Triterpenoids from Antrodia camphorata.
Antrodia camphorata is a rare and valuable medicinal mushroom. In this work, 11 new triterpenoids, namely, antcamphorols A-K (1-11), together with 10 known triterpenoids, 12-21, were isolated from dish-cultured A.
Niu-Chang-Chih · 2020 · Research Support, Non U.S. Gov'T · Brain and behavior
Antrodia camphorata polysaccharide resists 6-OHDA-induced dopaminergic neuronal damage by inhibiting ROS-NLRP3 activation.
INTRODUCTION: Parkinson's disease (PD) is a common degenerative disease of the central nervous system (CNS). The main pathological change is the apoptosis of dopaminergic neurons in the substantia nigra pars compacta (SNPc), thereby leading to dopamine reduction in nigral striatum..
Agarikon · 2020 · Research Support, Non U.S. Gov'T · Scientific reports
Medicinal potential of mycelium and fruiting bodies of an arboreal mushroom Fomitopsis officinalis in therapy of lifestyle diseases.
Fomitopsis officinalis is a medicinal mushroom used in traditional European eighteenth and nineteenth century folk medicine. Fruiting bodies of F.
Chaga · 2020 · Research Support, Non U.S. Gov'T · Bioorganic chemistry
Modified lanostane-type triterpenoids with neuroprotective effects from the fungus Inonotus obliquus.
Six undescribed lanostane triterpenoids (1-6), together with three known compounds (7-9) were isolated from Inonotus obliquus. Compounds 3-5 are the rare natural compounds featuring a 4,5-seco-lanostane core with a 5,7,9-trien-21,24-cyclopentane moiety..
Maitake · 2020 · Research Support, Non U.S. Gov'T · Journal of food biochemistry
The hypoglycemic and renal protective effects of Grifola frondosa polysaccharides in early diabetic nephropathy.
Grifola frondosa is a basidiomycete polypore fungus. Polysaccharides from G.
Niu-Chang-Chih · 2020 · Research Support, Non U.S. Gov'T · Integrative cancer therapies
The Leaf Extracts of Toona sinensis and Fermented Culture Broths of Antrodia camphorata Synergistically Cause Apoptotic Cell Death in Promyelocytic Leukemia Cells.
Toona sinensis is a common edible vegetable that is used in certain Chinese dishes and has importance in folk medicine. The leaf extracts of T sinensis possess and exhibit anticancer efficacy against various cancer cell types..
Niu-Chang-Chih · 2019 · Research Support, Non U.S. Gov'T · Journal of cellular physiology
Antrodia camphorata inhibits epithelial-to-mesenchymal transition by targeting multiple pathways in triple-negative breast cancers.
Antrodia camphorata (AC) exhibits potential for engendering cell-cycle arrest as well as prompting apoptosis and metastasis inhibition in triple-negative breast cancer (TNBC) cells..
Mesima · 2019 · Research Support, Non U.S. Gov'T · Integrative cancer therapies
Potential Impact of Phellinus linteus on Adherence to Adjuvant Treatment After Curative Resection of Pancreatic Ductal Adenocarcinoma: Outcomes of a Propensity Score-Matched Analysis.
BACKGROUND: Surgical resection followed by adjuvant chemotherapy is the only therapeutic option in pancreatic cancer. However, there is limited research evaluating methods of improving adherence to adjuvant treatment after curative resection..
Lion's Mane · 2018 · Research Support, Non U.S. Gov'T · The Journal of nutritional biochemistry
Polysaccharide of Hericium erinaceus attenuates colitis in C57BL/6 mice via regulation of oxidative stress, inflammation-related signaling pathways and modulating the composition of the gut microbiota.
Inflammatory bowel disease (IBD) is a disease caused by a dysregulated immune with unknown etiology. Hericium erinaceus (H.
Turkey Tail · 2018 · Research Support, Non U.S. Gov'T · PloS one
Potential activities and mechanisms of extracellular polysaccharopeptides from fermented Trametes versicolor on regulating glucose homeostasis in insulin-resistant HepG2 cells.
Polysaccharides derived from mushrooms have potential to control blood sugar, reduce insulin resistance and prevent diabetic complications. The intracellular polysaccharopeptides of Trametes versicolor (TV) have been used as immunologic and oncologic adjuvants..
Niu-Chang-Chih · 2016 · Research Support, Non U.S. Gov'T · International immunopharmacology
4,7-Dimethoxy-5-methyl-1,3-benzodioxole from Antrodia camphorata inhibits LPS-induced inflammation via suppression of NF-κB and induction HO-1 in RAW264.7 cells.
Several benzenoid compounds have been isolated from Antrodia camphorata are known to have excellent anti-inflammatory activity. In this study, we investigated the anti-inflammatory potential of 4,7-dimethoxy-5-methyl-1,3-benzodioxole (DMB), one of the major benzenoid compounds isolated from the mycelia of A..
Lion's Mane · 2016 · Research Support, Non U.S. Gov'T · Journal of ethnopharmacology
Anti-Helicobacter pylori activity of bioactive components isolated from Hericium erinaceus.
ETHNOPHARMACOLOGICAL RELEVANCE: The fungus Hericium erinaceus (Bull.) Pers is used in Chinese traditional medicine to treat symptoms related to gastric ulcers. Different extracts from the fungus were assessed for anti-Helicobacter pylori activity to investigate the antibacterial activity of the ethanol extracts from….
Maitake · 2016 · Research Support, Non U.S. Gov'T · International journal of biological macromolecules
Anti-tumor and immunomodulatory activity of selenium (Se)-polysaccharide from Se-enriched Grifola frondosa.
A polysaccharide termed Se-GP11 was extracted and purified from Se-enriched Grifola frondosa in our previous study. This study investigated the characterization, anti-tumor and immunomodulatory activity of Se-GP11..
Maitake · 2016 · Research Support, Non U.S. Gov'T · Nutrition and cancer
Grifola frondosa Glycoprotein GFG-3a Arrests S phase, Alters Proteome, and Induces Apoptosis in Human Gastric Cancer Cells.
GFG-3a is a novel glycoprotein previously purified from the fermented mycelia of Grifola frondosa with novel sugar compositions and protein sequencing. The present study aims to investigate its effects on the cell cycle, differential proteins expression, and apoptosis of human gastric cancer SGC-7901 cells..
Lion's Mane · 2016 · Research Support, Non U.S. Gov'T · Oxidative medicine and cellular longevity
Hericium erinaceus Inhibits TNF-α-Induced Angiogenesis and ROS Generation through Suppression of MMP-9/NF-κB Signaling and Activation of Nrf2-Mediated Antioxidant Genes in Human EA.hy926 Endothelial Cells.
Hericium erinaceus (HE) is an edible mushroom that has been shown to exhibit anticancer and anti-inflammatory activities. We investigated the antiangiogenic and antioxidant potentials of ethanol extracts of HE in human endothelial (EA.hy926) cells upon tumor necrosis factor-α- (TNF-α-) stimulation (10 ng/mL)..
Lion's Mane · 2016 · Retracted Publication · Journal of translational medicine
Hericium erinaceus mycelium and its isolated erinacine A protection from MPTP-induced neurotoxicity through the ER stress, triggering an apoptosis cascade.
BACKGROUND: Hericium erinaceus is an edible mushroom; its various pharmacological effects which have been investigated. This study aimed to demonstrate whether efficacy of oral administration of H..
Enoki · 2016 · Research Support, Non U.S. Gov'T · Food chemistry
Identification of flavonoids from Flammulina velutipes and its neuroprotective effect on pheochromocytoma-12 cells.
The flavonoids from Flammulina velutipes (FVF) were isolated and the chemical composition of FVF was identified by high-performance liquid chromatography/mass spectrometry (HPLC/MS)..
Shiitake · 2016 · Clinical Study · Alternative therapies in health and medicine
Improvement of QOL and Immunological Function With Lentinula Edodes Mycelia in Patients Undergoing Cancer Immunotherapy: An Open Pilot Study.
Context • Combined treatment with an extract of Lentinula edodes mycelia (LEM) and chemotherapy has been reported to improve quality of life (QOL) and immunological function in cancer patients. However, those effects have not been elucidated for patients receiving cancer immunotherapy..