MycoData

Enoki · 2004 · Patent · journal metadata

A STRAIN OF SOMATIC STRUCTURES OF EDIBLE BASIDIOMYCETE FLAMMULINA VELUTIPES (CURT.: FR.) SING. F.W.û PRODUCER OF ASCOCARP AND MYCELIUM WITH ANTIOXYGENIC PROPERTIES

A strain of somatic structures of edible basidiomycete F-vv of winter armillaria Flammulina velutipes (Curt.: Fr.) Sing. û producer of ascocarp and mycelium with antioxygenic properties..

Mesima · 2004 · Comparative Study · Archives of pharmacal research

An antioxidant hispidin from the mycelial cultures of Phellinus linteus.

In the course of screening for reactive oxygen species scavengers from natural products, an antioxidant was isolated from the mycelial culture broth of Phellinus linteus and identified as hispidin. The hispidin content was reached its maximum level at 12 days after onset of inoculation..

OncologyImmune supportEnergy & fatigueLiver support

Niu-Chang-Chih · 2004 · Research Support, Non U.S. Gov'T · FEMS microbiology letters

Anti-inflammatory activity of the extracts from mycelia of Antrodia camphorata cultured with water-soluble fractions from five different Cinnamomum species.

We have previously reported that polysaccharides extracted from fruiting bodies or cultured mycelia of Antrodia camphorata exhibit an anti-hepatitis B virus effect..

Niu-Chang-Chih · 2004 · Research Support, Non U.S. Gov'T · Planta medica

Evaluation of the anti-inflammatory activity of zhankuic acids isolated from the fruiting bodies of Antrodia camphorata.

We have previously shown that a concentrated ethanol extract of the fruiting bodies of Antrodia camphorata exhibited immunomodulating effects in human leukocytes and fourteen compounds including zhankuic acids A, B, C, and antcin K were identified in the extract..

Mesima · 2003 · Research Support, Non U.S. Gov'T · International immunopharmacology

Proteoglycan isolated from Phellinus linteus activates murine B lymphocytes via protein kinase C and protein tyrosine kinase.

Medicinal mushrooms are increasingly used to treat a wide variety of disease processes. Aqueous extract from the fruiting body or mycelia of Phellinus linteus has been reported to produce antitumor and immunomodulatory activities in vivo and in vitro.

OncologyImmune supportEnergy & fatigueMetabolic health

Niu-Chang-Chih · 2002 · Comparative Study · FEMS microbiology letters

Antrodia camphorata polysaccharides exhibit anti-hepatitis B virus effects.

Polysaccharides were extracted from fruiting bodies and cultured mycelia from five Antrodia camphorata strains. Polysaccharide profiles of the five strains, as determined by high-performance anion-exchange chromatography, showed varying yields and composition of neutral sugars.

Maitake · 2002 · Research Support, Non U.S. Gov'T · Journal of agricultural and food chemistry

Cyclooxygenase inhibitory and antioxidant compounds from the mycelia of the edible mushroom Grifola frondosa.

The bioassay-guided isolation and purification of the hexane extract of the cultured mycelia of Grifola frondosa led to the characterization of a fatty acid fraction and three compounds, ergosterol (1), ergostra-4,6,8(14),22-tetraen-3-one (2), and 1-oleoyl-2-linoleoyl-3-palmitoylglycerol (3)..

Cognition & nervesEnergy & fatigue

Enoki · 2000 · Research Support, Non U.S. Gov'T · FEMS microbiology letters

Basidiomycetous fungus Flammulina velutipes harbors two linear mitochondrial plasmids encoding DNA and RNA polymerases.

Basidiomycetous fungus Flammulina velutipes R15 strain had two linear plasmids in its mitochondria designated pFV1 and pFV2. They were double-stranded DNAs, whose sizes were 8.3 and 8.9 kb, respectively..

Almond Mushroom · 2026 · English Abstract · Huan jing ke xue= Huanjing kexue

[Structural Evolution and Carbon Emission Reduction Path in China's Power Sector Based on LEAP-ABM Model].

Exploring low-carbon transition pathways in the power sector holds significant importance for promoting comprehensive green transformation of the economy and society and achieving carbon neutrality goals..

Oyster Mushroom · 2026 · Preprint · journal metadata

Acoustic Performance and Life Cycle Assessment of a Mycelium-Based Insulation Composite Produced from Agricultural Waste

Mycelium-based composites (MBC) have already been applied in various fields like construction, architecture, packaging, waste management and many others, as a sustainable replacement material. The composites created from such materials are lightweight, biodegradable and can take many different geometrical shapes..

Immune supportEnergy & fatigueMetabolic health

Cordyceps · 2026 · Comparative Study · Fitoterapia

Comparative chemical profiles of fruiting bodies and mycelia of Cordyceps cicadae and Ophiocordyceps sobolifera, and Immunometabolic modulation by liquid-fermented mycelia.

Cordyceps cicadae and Ophiocordyceps sobolifera are entomopathogenic fungi often misidentified due to taxonomic ambiguity, leading to confusion in research and applications..

Cordyceps · 2025 · English Abstract · Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

[Network pharmacology and animal experiments reveal molecular mechanisms of Cordyceps sinensis in ameliorating heart aging and injury in mice by regulating Nrf2/HO-1/NF-κB pathway].

This study aims to explore the effects and mechanisms of the traditional Chinese medicine Cordyceps sinensis(CS) in ameliorating heart aging and injury in mice based on animal experiments and network pharmacology..

Cordyceps · 2025 · Review · The American journal of Chinese medicine

Cordycepin: A Promising Anticancer Compound from Traditional Chinese Medicine.

As cancer continues to pose a significant threat to human health, the search for effective therapeutic agents has become a critical focus in medical research. Cordyceps is a fungus used in traditional Chinese medicine (TCM) valued for its potential health benefits, which include boosting energy, supporting the immune….

Shiitake · 2025 · Evaluation Study · Journal of the science of food and agriculture

High-intensity ultrasound treatment of shiitake mushroom protein isolate: effects on physicochemical, structural properties, and functional performance.

BACKGROUND: With increasing consumer demand for healthy and sustainable food, plant proteins have been used widely in meat substitutes, dairy alternatives, and functional foods..

OncologyImmune supportEnergy & fatigueMetabolic health

Cordyceps · 2024 · English Abstract · Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases

[Research on ameliorating pulmonary fibrosis in silicosis mice of Cordyceps cicadae polysaccharides].

Objective: A mouse silicosis model was constructed by injecting silicon dioxide (SiO(2)) particles into the trachea to explore the effect and mechanism of Cordyceps cicadae polysaccharides (CCP) on ameliorating pulmonary fibrosis in silicosis mice..

Almond Mushroom · 2024 · Review · Journal of orthopaedic surgery and research

Correlation of metabolic markers and OPG gene mutations with bone mass abnormalities in postmenopausal women.

OBJECTIVE: The aim was to investigate the relationship between metabolic indices and abnormal bone mass (ABM), analyse the association between osteoprotegerin (OPG) gene mutations and ABM, and explore the interaction effect of type 2 diabetes mellitus (T2DM) and OPG gene mutations on bone mineral density (BMD) in….

Cognition & nervesEnergy & fatigue

Lion's Mane · 2024 · Scoping Review · Journal of the American Nutrition Association

The Role of Dietary Ingredients in Mental Energy - A Scoping Review of Randomized Controlled Trials.

Low mental energy can contribute to decreased productivity, altered life balance, decreased physical performance, and ultimately affect quality of life. As such, there is a great demand for food and beverage products that positively impact mental energy..

OncologyImmune supportCognition & nervesEnergy & fatigue

Cordyceps · 2023 · Research Article · Nutrients

Cordyceps cicadae NTTU 868 Mycelia Fermented with Deep Ocean Water Minerals Prevents D-Galactose-Induced Memory Deficits by Inhibiting Oxidative Inflammatory Factors and Aging-Related Risk Factors.

Cordyceps cicadae, a medicinal fungus that is abundant in bioactive compounds such as N6-(2-hydroxyethyl)-adenosine (HEA) and polysaccharides, possesses remarkable anti-inflammatory, antioxidant, and nerve damage recovery properties..

Immune supportCognition & nervesEnergy & fatigue

Shiitake · 2023 · Journal Article · Journal of food composition and analysis

Determination of polysaccharide content in shiitake mushroom beverage by NIR spectroscopy combined with machine learning: A comparative analysis

A comprehensive comparative analysis of the performance of near-infrared (NIR) spectroscopy combined with various chemometrics and machine learning methods was performed to quantitatively determine polysaccharide content in shiitake mushroom beverages..

Energy & fatigueMetabolic healthGut & microbiome

Reishi · 2023 · Journal Article · Frontiers in veterinary science

Ganoderma lingzhi culture enhance growth performance via improvement of antioxidant activity and gut probiotic proliferation in Sanhuang broilers.

INTRODUCTION: The experiment was conducted to evaluate the effects of Ganoderma lingzhi culture (GLC) as a fermented feed on growth performance, serum biochemical profile, meat quality, and intestinal morphology and microbiota in Sanhuang broilers..

Immune supportCognition & nervesEnergy & fatigueSkin & hydration

Cordyceps · 2023 · Research Article · Nutrients

Preventative Effects of Cordyceps cicadae Mycelial Extracts on the Early-Stage Development of Cataracts in UVB-Induced Mice Cataract Model.

Cataracts, a prevalent age-related eye condition, pose a significant global health concern, with rising rates due to an aging population and increased digital device usage. In Taiwan, cataract prevalence is particularly high, reaching up to 90% among individuals aged 70 and above..

OncologyImmune supportEnergy & fatigueLiver support

Cordyceps · 2023 · Journal Article · International journal of biological macromolecules

The cellular uptake of Cordyceps sinensis exopolysaccharide‑selenium nanoparticles and their induced apoptosis of HepG2 cells via mitochondria- and death receptor-mediated pathways.

This wok investigated the effects of Cordyceps sinensis exopolysaccharide‑selenium nanoparticles (EPS-SeNPs), EPS-Se-1, EPS-Se-2, EPS-Se-3, and EPS-Se-4) with particle sizes (79-124 nm) and Se contents (20.11-40.80 μg/mg) on endocytosis and antitumor activity against human hepatocellular carcinoma (HepG2) cells and….

Cognition & nervesEnergy & fatigue

Cordyceps · 2022 · Journal Article · Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

[Identification of Cordyceps cicadae and Tolypocladium dujiaolongae based on ITS sequences and chemical pattern recognition method].

Based on ITS sequences, the molecular identification of Cordyceps cicadae and Tolypocladium dujiaolongae was carried out, and high-performance liquid chromatography(HPLC) fingerprint combined with chemical pattern recognition method was established to differentiate C. cicadae from its adulterant T.

Reishi · 2022 · Journal Article · G3 (Bethesda, Md.)

Comparative transcriptome analysis of genes and metabolic pathways involved in sporulation in Ganoderma lingzhi.

Over the past decades, Ganoderma lingzhi spores have received considerable attention as a great potential pharmaceutical resource. However, the genetic regulation of sporulation is not well understood..

Energy & fatigueMetabolic healthSkin & hydration

Cordyceps · 2022 · Journal Article · RSC advances

Cordyceps sinensis-mediated biotransformation of notoginsenoside R1 into 25-OH-20(S/R)-R2 with elevated cardioprotective effect against DOX-induced cell injury.

Notoginsenoside R1 is a dammarane saponin in Panax notoginseng with promising cardioprotective effects. The bioactivity-structure relationship of such saponins suggested that the presence of a hydroxyl group at C25 could elevate its performance..

Immune supportEnergy & fatigueGut & microbiome

Cordyceps · 2022 · Journal Article · Frontiers in veterinary science

Effects of Coated Sodium Butyrate and Polysaccharides From Cordyceps cicadae on Intestinal Tissue Morphology and Ileal Microbiome of Squabs.

This experiment was conducted to investigate the effects of dietary supplementation with different levels of coated sodium butyrate (CSB) and polysaccharides extracted from Cordyceps cicadae (CCP) on growth performance, intestinal tissue morphology and ileum microbiome in squabs..

Oyster Mushroom · 2022 · Research Article · Frontiers in nutrition

Evaluation of Volatile Profile and In Vitro Antioxidant Activity of Fermented Green Tea Infusion With Pleurotus sajor-caju (Oyster Mushroom).

Green tea has distinct astringency, bitter taste, and typical green flavor because of its post-harvest treatment without withering and enzymatic oxidation. Microbial fermentation has been identified as a promising strategy that could give green tea infusion a special taste flavor..

Cordyceps · 2022 · Research Article · Heliyon

Optimization of Cordyceps sinensis fermentation Marsdenia tenacissima process and the differences of metabolites before and after fermentation.

In this paper, we explored the interaction of factors which influenced the Cordyceps sinensis fermentation Marsdenia tenacissima (Roxb.) Wight et Arn, a Dai (a national minority of China) medicine, and the optimal fermentation conditions. The differences of C..

Immune supportEnergy & fatigueSkin & hydration

Nameko · 2022 · Research Article · Antioxidants (Basel, Switzerland)

Pholiota nameko Polysaccharides Protect against Ultraviolet A-Induced Photoaging by Regulating Matrix Metalloproteinases in Human Dermal Fibroblasts.

Ultraviolet-A (UVA) exposure is a major cause of skin aging and can induce oxidative damage and accelerate skin wrinkling. Many natural polysaccharides exhibit a UV protective effect..

Immune supportEnergy & fatigueLiver support

Cordyceps · 2022 · Journal Article · International journal of biological macromolecules

Protective effects of Cordyceps sinensis exopolysaccharide‑selenium nanoparticles on H2O2-induced oxidative stress in HepG2 cells.

This work investigated the protective effects of Cordyceps sinensis exopolysaccharide‑selenium nanoparticles (EPS-SeNPs) at different Se/EPS ratios (1/20, 1/3, 1/1, and 4/3) against 0.4 mM H2O2-induced oxidative stress in human hepatoma (HepG2) cells..

Immune supportEnergy & fatigueMetabolic healthSkin & hydration

Cordyceps · 2021 · Journal Article · Frontiers in pharmacology

Cordyceps cicadae Ameliorates Renal Hypertensive Injury and Fibrosis Through the Regulation of SIRT1-Mediated Autophagy.

Hypertensive renal injury is a complication of hypertension. Cordyceps cicadae (C.

Cordyceps · 2021 · Journal Article · International journal of medicinal mushrooms

Optimization of In Vitro Culture Conditions for Production of Cordyceps bassiana Spores (Ascomycetes) and the Effect of Spore Extracts on the Health of Caenorhabditis elegans.

Cordyceps bassiana, an entomogenous fungus, has been used as a dietary therapeutic in traditional Chinese medicine for several millennia. However, naturally occurring C.

Energy & fatigueSkin & hydration

Shiitake · 2021 · Research Article · Foods (Basel, Switzerland)

Study on the Rehydration Quality Improvement of shiitake Mushroom by Combined Drying Methods.

The aim of study is to improve the rehydration quality of dried shiitake mushrooms for their instant food manufacturers and fast restaurants. Serial combined drying methods were investigated to achieve this objective: either instant controlled pressure drop drying (DIC) or freeze drying (FD) was used as the treatments….

Immune supportEnergy & fatigueMetabolic health

Cordyceps · 2021 · Journal Article · Frontiers in pharmacology

Supercritical Carbon Dioxide Extracts of Cordyceps sinensis: Chromatography-based Metabolite Profiling and Protective Efficacy Against Hypobaric Hypoxia.

The toxicity and disposal concerns of organic solvents used in conventional extraction purposes has entailed the need for greener alternatives. Among such techniques, supercritical fluid extraction (SFE) has gained popularity by yielding extracts of high purity in a much faster manner..

Immune supportEnergy & fatigueMetabolic healthLiver support

Oyster Mushroom · 2021 · Journal Article · Journal of proteomics

Tandem mass tag-based proteomics for studying the effects of a biotechnologically produced oyster mushroom against hepatic steatosis in obese Zucker rats.

Hepatic steatosis is a very common response to liver injury and often attributed to metabolic disorders. Prior studies have demonstrated the efficacy of a biotechnologically produced oyster mushroom (Pleurotus sajor-caju, PSC) in alleviating hepatic steatosis in obese Zucker rats..

Almond Mushroom · 2020 · Randomized Controlled Trial · European addiction research

Imaginal Retraining Reduces Cigarette Smoking: A Randomized Controlled Study.

OBJECTIVES: Smoking is a highly prevalent addictive behavior with severe and life-shortening health consequences. This is the first study to evaluate the efficacy of a newly developed imaginal variant of approach bias modification (ABM) (i.e., imaginal retraining) for the reduction of craving for tobacco and actual….

Immune supportEnergy & fatigue

Cordyceps · 2017 · Research Support, Non U.S. Gov'T · Trends in biotechnology

Myths and Realities Surrounding the Mysterious Caterpillar Fungus.

The caterpillar fungus Ophiocordyceps sinensis is a medicinal mushroom increasingly used as a dietary supplement for various health conditions, including fatigue, chronic inflammation, and male impotence..

Cordyceps · 2026 · Research Article · Fundamental research

Accumulation of the spontaneous and random mutations is causative of fungal culture degeneration.

Filamentous fungi frequently degenerate during subculturing, which manifests as the reduction or loss of conidiation, sexuality, secondary metabolite production, and/or virulence against hosts. The underlying mechanism of spontaneous fungal degeneration is still elusive..

Immune supportEnergy & fatigueMetabolic healthLiver support

King Oyster · 2026 · Journal Article · International journal of biological macromolecules

Antidiabetic effects of Agaricus bisporus polysaccharide in HFD/STZ-induced mice.

Fungal polysaccharides have garnered attention for their antidiabetic potential. Here, we evaluated five edible fungal polysaccharides-Agaricus bisporus (ABP), Pleurotus eryngii (PEP), Boletus spp.

OncologyImmune supportEnergy & fatigueSkin & hydration

Cordyceps · 2026 · Journal Article · Journal of chromatography. A

Construction of porous adsorbent for selective enrichment of cis-diol-containing flavonoids and evaluation of green performance based on life cycle analysis.

Flavonoids exhibit anti-inflammatory, anti-cancer, antibacterial and anti-aging properties. However, their complex structures make the separation and purification of flavonoids pharmacologically significant..

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

Cordyceps · 2026 · Journal Article · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Elucidation of mechanisms underlying the therapeutic effects of cordycepin on pulmonary hypertension, with a focus on cell senescence and gut microbiota.

INTRODUCTION: Pulmonary hypertension (PH) is a progressive cardiopulmonary disorder characterized by excessive pulmonary vascular remodeling and aberrant proliferation of pulmonary artery smooth muscle cells (PASMCs). Emerging evidence suggests that gut microbiota dysbiosis contributes to PH development..

Immune supportEnergy & fatigueRespiratory

Shiitake · 2026 · Research Article · Frontiers in immunology

Evaluation of Imoviral® effects on early immune response in Sparus aurata challenged with Vibrio anguillarum.

BACKGROUND: An acute phase response (APR) was experimentally induced in Sparus aurata (Linnaeus, 1758) by intraperitoneal (IP) injection of Vibrio anguillarum to evaluate the effects of dietary supplementation with the Imoviral® complex (CRISTALFARMA) on fish growth performance and health status, through the analysis….

Energy & fatigueGut & microbiome

Oyster Mushroom · 2026 · Journal Article · Journal of environmental management

Feasibility of soilless substrate systems supplemented with black soldier fly frass for sustainable mushroom cultivation.

The rising cost and limited availability of sawdust have driven interest in alternative substrates for mushroom cultivation. Black soldier fly larvae (BSFL) frass is a nutrient-rich byproduct of insect farming that could serve as a low-cost supplement, however, its effective incorporation requires a suitable substrate….

Immune supportEnergy & fatigueLiver supportSkin & hydration

Cordyceps · 2026 · Journal Article · Journal of ethnopharmacology

Paecilomyces hepiali Chen (Cs-4) polysaccharides ameliorate chronic liver fibrosis via inhibiting TGF-β1/Smad and NLRP3/Caspase-1-mediated hepatic stellate cells activation in vivo and in vitro.

ETHNOPHARMACOLOGICAL RELEVANCE: Paecilomyces hepiali Chen (Cs-4), recognized as the classic deficiency-tonifiying medicine of traditional Chinese medicine (TCM), is the principal and most valuable medicinal species of Ophiocordyceps sinensis (known as Cordyceps sinensis (Berk.) Sacc., or 'Dong-Chong-Xia-Cao' in….

Oyster Mushroom · 2026 · Research Article · World journal of microbiology & biotechnology

Utilization of lignocellulosic mushroom cultivation residues for bioethanol production via consolidated bioprocessing.

In the context of the energy transition, there is an increasing need for research focused on low-cost feedstocks, such as lignocellulosic biomass, and on process optimization for the sustainable production of biofuels. Traditionally, processing lignocellulosic materials requires multiple stages..

Immune supportEnergy & fatigue

King Oyster · 2025 · Journal Article · International journal of biological macromolecules

Blending polysaccharides from three edible mushrooms represents a promising approach for augmenting their anti-oxidant and anti-fatigue activities.

It has been well documented that a number of polysaccharides with potent free-radical scavenging capability possess notable anti-fatigue activity. Interestingly, recent evidence also suggested mixed polysaccharides derived from multiple sources may yield augmented bioactivities compared to the polysaccharides from a….

Immune supportCognition & nervesEnergy & fatigueLiver support

Cordyceps · 2025 · Research Article · Scientific reports

Cordycepin combined with antioxidant effects improves fatigue caused by excessive exercise.

Excessive exercise can lead to physical fatigue and disruption of the antioxidant system, resulting in neurological damage and cognitive decline. Cordycepin, the main component of Cordyceps militaris, has anti-inflammatory, antioxidant and neuroprotective effects..

Immune supportCognition & nervesEnergy & fatigueGut & microbiome

Cordyceps · 2025 · Journal Article · Molecular neurobiology

Cordycepin Mitigates Sepsis-Associated Encephalopathy by Promoting Microglial M2 Polarization via the IL-17a/IL-17RA/NF-κB Axis.

Sepsis-associated encephalopathy (SAE) is a serious neurological complication of systemic infection, marked by cognitive deficits, neuroinflammation, and increased mortality. Microglial activation and proinflammatory signaling pathways, particularly involving IL-17a and NF-κB, are key contributors to SAE pathogenesis..

Shiitake · 2025 · Journal Article · Food Packaging and Shelf Life

Preparation and characterization of a novel polyvinyl alcohol/pectin film containing bromocresol green-alizarin mixed indicator label for monitoring mushroom freshness

Intelligent indicator labels offer significant potential for real-time shelf-life assessment and quality preservation during perishable food logistics. This study developed a novel bromocresol green-alizarin (BGA) indicator-embedded polyvinyl alcohol (PVA)/pectin (P) composite film for visual freshness monitoring of….