MycoData

Turkey Tail · 2026 · Journal Article · Innovative Food Science and Emerging Technologies

Different strategies to obtain laccase-based time-temperature indicator for monitoring of cold chain storage and management

In this work, we have developed a battery of enzymatic time-temperature indicators (TTIs) based on the oxidation of 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) catalyzed by laccase from Trametes versicolor..

Turkey Tail · 2026 · Research Article · Small science

Electrochemical Biosensor Based on Hairy Core-Shell Particles: Effect of Core Conductivity.

In this study, the effect of the core material in hairy core-shell carriers with grafted poly(2-(dimethylamino)ethyl methacrylate) (PDMAEMA) polymer brushes containing immobilized laccase from Trametes versicolor (TvL) is investigated..

Energy & fatigueMetabolic healthGut & microbiome

Reishi · 2026 · Journal Article · Journal of hazardous materials

Fungal removal of OPFRs from urban wastewater in a rotary drum bioreactor.

Organophosphate flame retardants (OPFRs) removal is usually limited in conventional treatment systems. This study assessed the long-term removal of five OPFRs (TBP, TBEP, TCEP, TCPP and TEP) in wastewater using rotating drum bioreactors (RDBs) inoculated with a white-rot fungi (WRF) consortium (Trametes versicolor,….

Turkey Tail · 2026 · Research Article · Angewandte Chemie (International ed. in English)

Harnessing Colloidal Dispersion for Laccase-Driven Enzymatic Depolymerization of Polystyrene.

Polystyrene (PS) is one of the most widely used synthetic polymers, with annual global production of around 20 million tons. However, its robust C─C backbone renders it highly recalcitrant to (bio)chemical depolymerization, and no sustainable re-/up-cycling method has yet been developed..

OncologyImmune supportEnergy & fatigueSkin & hydration

Cordyceps · 2026 · Journal Article · International journal of medicinal mushrooms

Immunomodulatory Effects of Medicinal Mushroom Extracts in the Sensitized Human Keratinocyte Cell Line NCTC2544.

Contact dermatitis (CD) is a common skin condition characterized by inflammation caused by exposure to allergens. In Malaysia, it accounts for a significant portion of skin diseases, with irritant contact dermatitis being the most prevalent type..

OncologyImmune supportCognition & nervesEnergy & fatigue

Reishi · 2026 · Research Article · International journal of molecular sciences

In Vitro Anti-Glioblastoma Activity of a Novel Pt(IV)-Ganoderic Acid A Conjugate.

Glioblastoma is the most aggressive primary malignant tumor of the central nervous system in adults, with a poor prognosis and high resistance to conventional therapies. Platinum drugs like cisplatin are effective but limited by systemic toxicity, poor blood-brain barrier penetration, and resistance..

Turkey Tail · 2026 · Journal Article · International journal of biological macromolecules

Laccase-peroxidase synergy modifies Kraft lignin structure and enhances the electrospinnability for bio-based materials.

Lignin is a promising renewable macromolecular feedstock for advanced carbon-based materials; however, its intrinsic molecular heterogeneity, relatively low molecular weight, and limited thermal stability often hinder direct fiber formation..

Reishi · 2026 · Journal Article · Bioresource technology

Lignocellulolytic fungi to tailor hydrophobic microstructures of biochar for efficient and selective removal of diverse emerging contaminants.

The co-occurrence of multiple classes of emerging contaminants (ECs) in water bodies, such as phenolic compounds (PCs), extracellular DNA (eDNA), and nanoscale plastics (PSNP), complicates their simultaneous removal due to divergent physicochemical properties..

Turkey Tail · 2026 · Journal Article · Journal of hazardous materials

Mechanistic insights into the enhancement of azithromycin biodegradation by extracellular polymeric substances: Roles of metabolic activity, electron transfer, and reactive oxygen species.

White-rot fungi (WRF) have shown potential as an effective alternative for antibiotic removal in wastewater treatment. However, their slow degradation rates remain a major challenge..

Shiitake · 2026 · Journal Article · Ecotoxicology and environmental safety

Metal-organic framework-hybridized immobilized laccase for the efficient degradation of industrial wastewater pollutants.

Natural laccases from Lentinula edodes exhibit remarkable catalytic versatility in degrading various organic pollutants in industrial wastewater. However, their practical applications are limited by their inherent structural instability and poor reusability..

Turkey Tail · 2026 · Journal Article · Bioresource technology

Molecular orbital-guided design of laccase-mediator systems for antibiotic removal in the presence of humic acid.

Antibiotic residues, as emerging environmental contaminants, have raised significant concerns, underscoring the urgent need for efficient laccase-mediator systems (LMS) to facilitate their removal..

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

Lion's Mane · 2026 · Journal Article · International journal of biological macromolecules

Multiscale interaction of Hericium coralloides polysaccharide with maize starch: Impact on structural properties and digestibility.

Regulating starch digestion to alleviate postprandial hyperglycemia is one of the core challenges in the field of nutrition. Edible mushroom polysaccharides have become highly promising natural starch modifiers due to their dual functions of modulating food structure and potentially inhibiting digestive enzyme….

Enoki · 2026 · Journal Article · ACS synthetic biology

Mushroom Derived STS-HMGS Fusion Enzyme Enhances Sesquiterpene Production in Fungal Hosts.

3-Hydroxy-3-methylglutaryl-CoA synthase (HMGS) is a key enzyme in the mevalonate (MVA) pathway that catalyzes the formation of 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) from acetoacetyl-CoA and acetyl-CoA. Recently, a novel class of HMGS-sesquiterpene synthase (STS) fusion enzymes has been identified..

Yellow Morel · 2026 · Journal Article · Molecular diversity

Novel oleanolic acid derivatives containing piperazine pyrimidine moieties: design, synthesis, and antimicrobial activity.

Natural products are main sources of new chemical entities for pesticide discovery and also important modification substrates for activity enhancement. In this study, a series of novel oleanolic acid derivatives containing piperazine pyrimidine structures were designed and synthesized..

Energy & fatigueMetabolic healthGut & microbiome

Zhu Ling · 2026 · Journal Article · Cellular and molecular life sciences: CMLS

Renal fibrosis is induced by hyperactive Wnt/β-catenin pathway via microbial-mediated tryptophan metabolism-driven AhR signaling in rodents and humans.

Renal fibrosis is a common pathological endpoint in progressive chronic kidney disease (CKD). Clinical evidence indicates that a decline in renal function is more closely associated with tubulointerstitial fibrosis (TIF) than with glomerular injury..

Immune supportEnergy & fatigueGut & microbiomeSkin & hydration

Oyster Mushroom · 2026 · Research Article · Aquaculture nutrition

Species- and Level-Dependent Modulation of Growth and Skin and Intestinal Mucosal Microbiota in Rainbow Trout Fed Mushroom Stem Meals.

Mucosal microbiomes play key roles in fish physiology by supporting digestion, nutrient absorption, metabolism, immune modulation, and pathogen defense. This study evaluated the effects of mushroom stem meals from Agaricus bisporus (AB) and Pleurotus ostreatus (PO) as nutritional alternatives to soybean meal (SBM) on….

Shiitake · 2026 · Journal Article · Phytopathology

The Host Range and Pathogenic Potential Differences Between Aphelenchoides oryzae and Aphelenchoides pseudobesseyi.

Foliar nematodes within the Aphelenchoides besseyi species complex are economically important plant parasites. Unfortunately, the species delimitation and their host range have been unclear because these nematodes were long considered a single species.

Immune supportEnergy & fatigueSkin & hydration

Oyster Mushroom · 2026 · Journal Article · Pharmaceuticals (Basel, Switzerland)

The Use of Biomass from In Vitro Fungal Cultures as a Bioactive Ingredient with Antimicrobial Activity in Hydrogel Dressings.

Background/Objectives: Chronic wounds represent a significant clinical burden and require multimodal treatment strategies targeting inflammation, infection, moisture balance, and tissue remodeling, as defined by the TIME framework..

Immune supportEnergy & fatigueMetabolic healthSkin & hydration

Snow Fungus · 2026 · Research Article · Regenerative biomaterials

Three-dimensional-printed ROS-scavenging and immunomodulatory hydrogel accelerates diabetic wound healing through synergistic microenvironment regulation.

The management of diabetic wounds remains clinically challenging, primarily owing to three interrelated pathological mechanisms: excessive accumulation of reactive oxygen species (ROS), dysregulated angiogenesis and sustained, non-resolving inflammation..

Energy & fatigueGut & microbiome

Turkey Tail · 2026 · Journal Article · Scientific reports

Valorisation of waste OSB into sustainable mycelium-based composites for insulation applications.

The need for the construction industry to reduce its contribution to landfill waste and greenhouse gas emissions is urgent, with engineered wood products such as oriented strand board (OSB) representing a complex and difficult-to-recycle waste stream..

Turkey Tail · 2026 · Research Article · Polymers

Walls That Grow: Fungal Species-Driven Performance of Mycelium-Based Composites Grown on Rice-Husk Waste.

Mycelium-based composites (MBCs) are gaining attention as sustainable alternatives to conventional materials because they are grown biologically rather than produced through resource-intensive extraction and processing..

OncologyImmune supportCognition & nervesEnergy & fatigue

Agarikon · 2025 · Journal Article · International journal of biological macromolecules

A TME-responsive polysaccharide nanoplatform integrating synergetic therapy for cancer.

A self-assembling nanoplatform based on FOB (a heteropolysaccharide from Fomitopsis officinalis) named QU@FOB-FcDBA was developed in this study. A dynamic boronate ester bond, a pH-sensitive covalent linkage formed through reversible dehydration reactions, linked FOB and 1,1'-ferrocenediboronic acid (FcDBA) while….

Turkey Tail · 2025 · Research Article · ChemistryOpen

Biosensor Based on the Immobilization of Laccase on β-Cyclodextrin Membrane for the Evaluation of Antioxidant Capacity in Real Samples.

The optimization of a new amperometric biosensor for evaluating antioxidant capacity in real samples is reported. The biosensor is based on the immobilization of Laccase from Trametes versicolor on an electropolymerized β-cyclodextrin polymeric membrane on a glassy carbon electrode..

OncologyImmune supportEnergy & fatigueGut & microbiome

Oyster Mushroom · 2025 · Research Article · BMC complementary medicine and therapies

Computational development of mushroom-6-glucan/paclitaxel as a synergistic complementary medicine for breast cancer therapy.

BACKGROUND: Breast cancer is chemo-resistant and highly metastatic, often resulting in patient mortality. One of the primary factors contributing to the metastasis and chemotherapy resistance is the presence of cancer stem-like cells..

Turkey Tail · 2025 · Research Article · Biotechnology journal

Conductive Hairy Particles With Homogeneous and Janus Design as Carrier Materials for the Efficient Immobilization of Unspecific Peroxygenases.

Efficient immobilization of unspecific peroxygenases (UPOs) on hairy particles with homogeneous and Janus design possessing conductive core and polymeric shell was demonstrated..

Turkey Tail · 2025 · Journal Article · Engineering in life sciences

Design of a Biocatalytic Filter for the Degradation of Diclofenac and Its Ozonation Products.

Posttreatment of the effluents from wastewater treatment plants is becoming increasingly important, as the conventional treatment cannot completely remove organic trace contaminants..

OncologyImmune supportEnergy & fatigueMetabolic health

Niu-Chang-Chih · 2025 · Research Article · Molecular medicine reports

Eburicoic acid inhibits endothelial cell pyroptosis and retards the development of atherosclerosis through the Keap1/Nrf2/HO‑1/ROS pathway.

Atherosclerosis (AS)‑related coronary artery disease is the main cause of morbidity and mortality around the globe. Eburicoic acid, a triterpenoid compound from Antrodia camphorata, exerts anti‑inflammatory and anti‑hyperlipidemic effects, although its role in atherogenesis remains unknown..

Immune supportCognition & nervesEnergy & fatigue

Lion's Mane · 2025 · Journal Article · The Journal of pharmacy and pharmacology

Effects of dietary supplementation with arboreal medicinal mushrooms on stress coping strategies, depressive and anxiety-like behavior of rats.

BACKGROUND: Preclinical studies have demonstrated that the edible arboreal medicinal mushroom Hericium erinaceus (HE) mitigates high corticosterone levels and enhances stress-coping strategies in rodents, with emerging evidence suggesting similar neuroprotective potential for Fomitopsis officinalis (FO) and Pleurotus….

OncologyImmune supportEnergy & fatigueSkin & hydration

Reishi · 2025 · Journal Article · International journal of biological macromolecules

Effects of Ganoderma spent substrate containing with polysaccharides and triterpenoids on the growth performance, antioxidant capacity and immunity level of chickens.

Ganoderma spent substrate (GSS) is the residual material of Ganoderma lucidum (GL) cultivation, which has abundant polysaccharides and triterpenoids. GL is widely recognized for its antioxidant and immune-boosting properties, however, the effects of GSS remain largely unexplored..

Oyster Mushroom · 2025 · Research Article · Current issues in molecular biology

Enzymatic Activity and Nutrient Profile Assessment of Three Pleurotus Species Under Pasteurized Cenchrus fungigraminus Cultivation.

Oyster mushrooms are regarded as one of the most significant edible mushrooms in terms of commercial value because of their rich nutritional profile. Many bioactive extracts from Pleurotus species have been found to exhibit antitumor and antioxidant activities..

OncologyEnergy & fatigue

OncologyImmune supportEnergy & fatigueSkin & hydration

Reishi · 2025 · Research Article · Frontiers in pharmacology

Evaluation of in vitro pharmacological activities of medicinal mushrooms in the context of dry eye disease.

INTRODUCTION: Ethnic groups worldwide use mushrooms, particularly polypores (a group of fungi with woody fruiting bodies), to manage inflammatory conditions. In this study, the in vitro anti-inflammatory potential and mycochemical composition of six polypore extracts derived from the fruit bodies of Fomes fomentarius….

Oyster Mushroom · 2025 · Research Article · Foods (Basel, Switzerland)

Evaluation of the Gelation Characteristics and Printability of Edible Filamentous Fungi Flours and Protein Extracts.

There is a pressing need to produce novel food ingredients from sustainable sources to support a growing population. Filamentous fungi can be readily cultivated from low-cost agricultural byproducts to produce functional proteins for food biomanufacturing of structured products..

Oyster Mushroom · 2025 · Journal Article · Industrial crops and products

Fungal mycelium enhanced magnetic biochar from rice straw for efficient tetracycline adsorption: A sustainable strategy for agricultural waste valorization

This study presents a sustainable fungal-biochar refinery approach to convert rice straw into a high-performance magnetic adsorbent. The material was synthesized via solid-state fermentation using Pleurotus ostreatus followed by carbonization and KHCO₃ activation at 900 °C..

OncologyImmune supportEnergy & fatigue

Lion's Mane · 2025 · Journal Article · Histology and histopathology

Galangin alleviates gastric mucosal injury in rats with chronic atrophic gastritis by reducing ferroptosis.

OBJECTIVE: Chronic atrophic gastritis (CAG) is a precancerous lesion and is the first stage in a multistep precancerous cascade that can lead to gastric adenocarcinoma. This study aimed to reveal the role and mechanism of galangin in CAG..

Immune supportCognition & nervesEnergy & fatigue

Reishi · 2025 · Journal Article · J Nat Med

Ganoderic acid A ameliorated LPS-induced depression-like behaviors via suppression of acute neuroinflammation

Research context reveals that major depressive disorder (MDD), as a prevalent chronic relapsing psychiatric condition affecting up to one-third of patients with treatment resistance, necessitates urgent development of novel therapeutic agents..

Immune supportCognition & nervesEnergy & fatigue

Reishi · 2025 · Journal Article · Journal of natural medicines

Ganoderic acid A ameliorated LPS-induced depression-like behaviors via suppression of acute neuroinflammation.

Reishi · 2025 · Research Article · Theranostics

GLSP mitigates vascular aging by promoting Sirt7-mediated Keap1 deacetylation and Keap1-Nrf2 dissociation.

Background and Purpose: Vascular aging is a prior marker of human aging and a significant contributor to atherosclerosis and vascular calcification. However, there are limited pharmacological options available to mitigate vascular aging..

OncologyImmune supportEnergy & fatigueRespiratory

Oyster Mushroom · 2025 · Research Article · Biotechnology and bioengineering

Gold Nanoparticles Coated With Hydrophobin-ProteinA Fusion Protein: Development of a Versatile Immunosensing Platform.

Advancing immunosensing technologies hinges on the development of next-generation surface functionalization methods, as the precise anchoring of antibodies on transducer interface is essential for achieving high sensitivity and selectivity..

Shiitake · 2025 · Journal Article · International journal of medicinal mushrooms

Identification and Quantification of α-D-Glucopyranosyl-Isomaltol, α-D-Maltosyl-Isomaltol, and α-Glucan in AHCCŴ Cultured Mushroom Mycelia Extract.

Consumer demand and use of mushrooms and their extracts for health promotion is increasing in the United States and worldwide. In order to further advance the science and quality assurance of mushroom products and ingredients, analytical data is needed to identify and standardize biochemical markers..

Mesima · 2025 · Journal Article · International journal of medicinal mushrooms

In Silico Interaction of Phellilane L with HmuY: A Promising Therapeutic Strategy against Porphyromonas gingivalis in Chronic Periodontitis.

This study investigates the in silico interaction between Phellilane L, a sesquiterpene metabolite from Phellinus linteus, and the Porphiromonas gingivalis HmuY protein, a key player in chronic periodontitis pathogenesis..

Cognition & nervesEnergy & fatigue

Reishi · 2025 · Journal Article · International journal of medicinal mushrooms

In Silico Investigation of Ganoderic Acid A Targeting Amyloid-Beta and Tau Protein Aggregation in Alzheimer's Disease.

Alzheimer's disease (AD) represents a significant challenge in neurodegenerative disorders, characterized by the accumulation of amyloid-beta (Aβ) plaques and tau protein tangles in the brain. Current treatments provide symptomatic relief but do not halt disease progression..

Energy & fatigueGut & microbiome

Oyster Mushroom · 2025 · Research Article · Veterinary world

In vitro evaluation of ammoniation-fungal fermentation of citronella straw: Impacts on digestibility, ruminal fermentation, and palatability in Indonesian native sheep.

BACKGROUND AND AIM: Citronella straw (Cymbopogon nardus L.), a byproduct of essential oil extraction, is rich in lignin therefore poorly digestible, which limits its use as livestock feed..

Oyster Mushroom · 2025 · Journal Article · The Science of the total environment

Inclusion of biochar in mushroom substrate influences microbial community composition of the substrate and elemental composition of the fruiting bodies.

Due to its structure, biochar makes the soil porous and oxygen-rich, enhancing the water-holding capacity and increasing the cation exchange capacity for a longer duration. These aspects could also be favourable for mushroom production.

OncologyImmune supportEnergy & fatigueMetabolic health

Zhu Ling · 2025 · Journal Article · Journal of ethnopharmacology

Injinoryeong-San attenuates metabolic dysfunction-associated steatohepatitis via regulation of YAP/TAZ-signaling pathway.

ETHNOPHARMACOLOGICAL RELEVANCE: Injinoryeong-san (IJO), known as Yinchen-Wuling Powder in Chinese medicine, is a traditional herbal formula comprising six herbal medicinal plants, including Atractylodes macrocephala Koidz., Polyporus umbellatus (Pers.) Fries, Poria cocos (Schw.) Wolf, Cinnamomum cassia Presl, Alisma….

Turkey Tail · 2025 · Research Article · Biotechnology for biofuels and bioproducts

Insight into the role of antioxidant in microbial lignin degradation: Ascorbic acid as a fortifier of lignin-degrading enzymes.

BACKGROUND: Microbial-driven lignin depolymerization has emerged as a promising approach for lignin degradation. However, this process is hindered by the limited activity of lignin-degrading enzymes.

OncologyImmune supportEnergy & fatigue

Shiitake · 2025 · Journal Article · International Journal of Biological Macromolecules

Lentinan attenuates histone deacetylation of SOCS1 promoter to remodel autophagy via JAK2/STAT3 pathway for the prevention of intervertebral disc degeneration

Intervertebral disc degeneration (IVDD), driven by nucleus pulposus cell (NPCs) apoptosis, extracellular matrix (ECM) dyshomeostasis, and inflammation, lacks effective therapies. Lentinan (LNT), a polysaccharide from lentinula edodes, has anti-inflammatory and antioxidant properties..

OncologyImmune supportEnergy & fatigue

Shiitake · 2025 · Journal Article · International journal of biological macromolecules

Lentinan attenuates histone deacetylation of SOCS1 promoter to remodel autophagy via JAK2/STAT3 pathway for the prevention of intervertebral disc degeneration.

Reishi · 2025 · Journal Article · Bioresource Technology Reports

Mycelium biocomposites from agricultural and paper waste: Sustainable alternative to plastic foam based secondary packaging

Plastic foams like Expanded polystyrene (EPS) and Expanded Polyethylene (EPE), though common in packaging, are environmentally harmful due to their non-biodegradable nature—especially in regions with poor waste management..