MycoData

Mycelial growth in a defined medium by submerged fermentation is a rapid and alternative method for obtaining fungal biomass of consistent quality. Biomass, exopolysaccharides (EPS) and intracellular polysaccharides (IPS) production were optimised by response surface methodology in Lentinula edodes strain LeS (NCBI….

Immune support

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Chaga · 2016 · Journal Article · Molecular medicine reports

Polysaccharide isolated from the liquid culture broth of Inonotus obliquus suppresses invasion of B16-F10 melanoma cells via AKT/NF-κB signaling pathway.

A number of polysaccharides exhibit pharmacological activities. Polysaccharides derived from Inonotus obliquus (PLIO) appear to have various potential pharmacological properties, including anti‑tumor activity.

OncologyImmune support

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Lion's Mane · 2016 · Journal Article · Current microbiology

Protective Effects of Extracellular and Intracellular Polysaccharides on Hepatotoxicity by Hericium erinaceus SG-02.

The protective effects of extracellular and intracellular polysaccharides from Hericium erinaceus SG-02 on the CCl4-induced hepatic injury of mice were investigated in this work..

Immune supportMetabolic healthLiver support

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Shiitake · 2016 · Journal Article · Food & function

Proteomic analysis of intestinal tissues from mice fed with Lentinula edodes-derived polysaccharides.

Lentinula edodes-derived polysaccharides are well known for their immunomodulation and antitumor activities. However, the mechanisms of action have not been fully elucidated..

OncologyImmune supportGut & microbiome

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Maitake · 2016 · Journal Article · Food & function

Structural characterization and immunomodulatory activity of Grifola frondosa polysaccharide via toll-like receptor 4-mitogen-activated protein kinases-nuclear factor κB pathways.

We isolated a neutral polysaccharide from the fruiting body of a mushroom Grifola frondosa (GFP-A). The aim of this study was to characterize a neutral α-d-polysaccharide derived from G..

OncologyImmune support

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Mesima · 2016 · Journal Article · International journal of biological macromolecules

Structure and antioxidative property of a polysaccharide from an ammonium oxalate extract of Phellinus linteus.

In this paper, the novel polysaccharide PL-A11 was purified from an ammonium oxalate extract of Phellinus linteus mycelia. Its physicochemical properties, structural characteristics, and antioxidant activities were investigated..

Immune supportMetabolic healthLiver supportSkin & hydration

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Lion's Mane · 2016 · Research Article · International journal of molecular sciences

The Neuroprotective Properties of Hericium erinaceus in Glutamate-Damaged Differentiated PC12 Cells and an Alzheimer's Disease Mouse Model.

Hericium erinaceus, an edible and medicinal mushroom, displays various pharmacological activities in the prevention of dementia in conditions such as Parkinson's and Alzheimer's disease. The present study explored the neuroprotective effects of H..

OncologyImmune supportCognition & nervesEnergy & fatigue

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Lion's Mane · 2014 · Review · Applied microbiology and biotechnology

Medicinal properties of Hericium erinaceus and its potential to formulate novel mushroom-based pharmaceuticals.

Hericium erinaceus is an important mushroom with edible values and medicinal properties. Both the mycelium and the fruiting bodies contain many bioactive compounds with drug efficacy..

OncologyImmune supportCognition & nervesGut & microbiome

High relevance

Chaga · 2013 · Review · Asian Pacific journal of cancer prevention: APJCP

Progress on understanding the anticancer mechanisms of medicinal mushroom: inonotus obliquus.

Cancer is a leading cause of death worldwide. Recently, the demand for more effective and safer therapeutic agents for the chemoprevention of human cancer has increased.

OncologyImmune supportSkin & hydrationRespiratory

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Niu-Chang-Chih · 2012 · Review · International journal of medicinal mushrooms

Review of biological and pharmacological activities of the endemic Taiwanese bitter medicinal mushroom, Antrodia camphorata (M. Zang et C. H. Su) Sh. H. Wu et al. (higher Basidiomycetes).

Antrodia camphorata is an extremely rare fungus native to the forested regions of Taiwan. It is also a traditional Chinese medicine, and Taiwanese aborigines applied it for treating liver diseases and protecting from food and drug intoxication.

OncologyImmune supportMetabolic healthLiver support

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Niu-Chang-Chih · 2011 · Review Article · Evidence-based complementary and alternative medicine: eCAM

Review of Pharmacological Effects of Antrodia camphorata and Its Bioactive Compounds.

Antrodia camphorata is a unique mushroom of Taiwan, which has been used as a traditional medicine for protection of diverse health-related conditions. In an effort to translate this Eastern medicine into Western-accepted therapy, a great deal of work has been carried out on A.

OncologyImmune support

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Chaga · 2010 · Review · Journal of biomedicine & biotechnology

Anti-inflammatory effects of Inonotus obliquus in colitis induced by dextran sodium sulfate.

A total of 28 male BALB/c mice (average weight 20.7 +/- 1.6 g) were divided into 4 treatment groups and fed a commercial diet (A), a commercial diet + induced colitis by dextran sodium sulfate (DSS) (B), Inonotus obliquus (IO) administration (C), and IO administration + induced colitis by DSS (D)..

OncologyImmune supportGut & microbiome

High relevance

Mesima · 2010 · Review Article · Experimental and therapeutic medicine

Medicinal mushroom Phellinus linteus as an alternative cancer therapy.

Alternative cancer treatment with nutritional/dietary supplements containing a wide variety of herbal products is on the rise in Western countries. Recent epidemiological studies have suggested that mushrooms may prevent against different types of cancers..

OncologyImmune support

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Niu-Chang-Chih · 2009 · Review · Journal of ethnopharmacology

Niuchangchih (Antrodia camphorata) and its potential in treating liver diseases.

Niuchangchih (Antrodia camphorata (M. Zang & C.H.

OncologyImmune supportMetabolic healthLiver support

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Mesima · 2008 · Review · Current medicinal chemistry

A medicinal mushroom: Phellinus linteus.

Phellinus Linteus (Berkeley & M. A.

OncologyImmune support

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Maitake · 2005 · Journal Article · Oncology reports

Enhancement of cytotoxicity of NK cells by D-Fraction, a polysaccharide from Grifola frondosa.

In innate immunity, activated natural killer (NK) cells attack and damage pathogens such as bacteria and virus without restriction by the MHC antigen. NK cells activated by IL-12 have been reported to recognize and kill tumor cells in perforin-mediated apoptosis..

OncologyImmune supportRespiratory

High relevance

Chaga · 2005 · Research Article · Mycobiology

Immunomodulatory Activity of the Water Extract from Medicinal Mushroom Inonotus obliquus.

The immunomodulatory effect of aqueous extract of Inonotus obliquus, called as Chaga, was tested on bone marrow cells from chemically immunosuppressed mice. The Chaga water extract was daily administered for 24 days to mice that had been treated with cyclophosphamide (400 mg/kg body weight), immunosuppressive….

OncologyImmune supportMetabolic healthGut & microbiome

High relevance

Turkey Tail · 2005 · Research Article · Wei sheng wu xue tong bao

The optimization of manganese peroxidase production by {\sl Trametes versicolor}

Metadata-grounded summary: This research article indexes research on Trametes versicolor in Wei sheng wu xue tong bao in 2005. MycoData maps the paper to oncology, immune support based on its title, species context, article metadata, and study classification..

OncologyImmune support

High relevance

Maitake · 2004 · Journal Article · Journal of medicinal food

Administration of a polysaccharide from Grifola frondosa stimulates immune function of normal mice.

We have reported that D-Fraction, a polysaccharide extracted from the edible maitake mushroom (Grifola frondosa), activates immunocompetent cells, thereby eliciting antitumor activity..

OncologyImmune support

High relevance

Lion's Mane · 2004 · Research Article · Heilongjiang Medicine and Pharmacy

Isolation, purification and activity of polysaccharide from Hericium erinaceus

The mitotic activity of the transplantable mouse tumors, Sarcoma 37, Krebs-2, and Ehrlich carcinomas, in the ascites form, were inhibited after treatment with a mixture of vitamins C and B12 with no apparent toxic side effects..

OncologyImmune support

High relevance

King Oyster · 2004 · Research Article · Journal of Hebei Agricultural University

Study on liquid culture and polysaccharide antioxidation of Pleurotus eryngii

Terminal renal failure secondary to the hemolytic uremic syndrome (HUS) developed 18 months after initial transplantation and 4 1/2 months after the child received his second cadaveric renal allograft..

Immune supportMetabolic health

High relevance

Maitake · 2004 · Research Article · Zhongshan da xue xue bao. Zi ran ke xue ban = Acta scientiarum naturalium Universitatis Sunyatseni

UV induced mutagenesis of Grifola frondosa

Metadata-grounded summary: This research article indexes research on Grifola frondosa in Zhongshan da xue xue bao. Zi ran ke xue ban = Acta scientiarum naturalium Universitatis Sunyatseni in 2004.

Immune support

High relevance

Maitake · 2003 · Journal Article · Journal of medicinal food

Effect of Maitake (Grifola frondosa) D-Fraction on the activation of NK cells in cancer patients.

Maitake D-Fraction, extracted from maitake mushroom, has been reported to exert its antitumor effect in tumor-bearing mice by enhancing the immune system through activation of macrophages, T cells, and natural killer (NK) cells..

OncologyImmune supportLiver supportRespiratory

High relevance

Maitake · 2002 · Journal Article · Japanese journal of pharmacology

A Polysaccharide, Extract From Grifola frondosa, Induces Th-1 Dominant Responses in Carcinoma-Bearing BALB/c Mice

A polysaccharide, designated as the D-fraction, extracted from maitake (Grifola frondosa), was reported to have anti-tumor effects by activating macrophages and T cells in C3H/HeN mice in which a Th-1 dominant response was established..

OncologyImmune support

High relevance

Zhu Ling · 2002 · Journal Article · Jilin nong ye da xue xue bao = Acta agriculturae universitatis jilinensis

A Preliminary Report on the Study of Selecting Formulas for Liquid Culture Media of Polyporus umbellatus

Metadata-grounded summary: This journal article indexes research on Polyporus umbellatus in Jilin nong ye da xue xue bao = Acta agriculturae universitatis jilinensis in 2002. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Immune support

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Maitake · 2002 · Journal Article · Biological & pharmaceutical bulletin

Effect of Maitake (Grifola frondosa) D-Fraction on the Control of the T Lymph Node Th-1/Th-2 Proportion

We have already reported that the D-Fraction, a beta-glucan extracted from the fruiting body of the maitake mushroom (Grifola frondosa), activates cellular immunity and expresses anti-tumor effects..

OncologyImmune support

High relevance

Enoki · 2002 · Journal Article · Chinese Journal of Eco-Agriculture

Effects of CO_(2) concentration on the growth and development of Flammulina velutipes

Metadata-grounded summary: This journal article indexes research on Flammulina velutipes in Chinese Journal of Eco-Agriculture in 2002. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Immune support

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Maitake · 2002 · Journal Article · Biological & pharmaceutical bulletin

Effects of D-Fraction, a Polysaccharide from Grifola frondosa on Tumor Growth Involve Activation of NK Cells

Natural killer (NK) cells are directly cytotoxic for tumor cells and play a primary role in regulating immune responses. We monitored levels of NK cell cytotoxic activity in cancer patients receiving D-Fraction extracted from maitake mushrooms (Grifola frondosa)..

OncologyImmune support

High relevance

Maitake · 2002 · Journal Article · Journal of Wuxi University of Light Industry

Preliminary Studies on Preparation of Liquid Inoculum and Solid Medium Cultivation of Grifola frondosa

Metadata-grounded summary: This journal article indexes research on Grifola frondosa in Journal of Wuxi University of Light Industry in 2002. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Immune support

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Maitake · 2001 · Journal Article · Huadong shifan daxue xuebao = Journal of East China Normal University

Analysis of polysaccharide isolated from the fruit bodies and mycelia of Grifola frondosa

Metadata-grounded summary: This journal article indexes research on Grifola frondosa in Huadong shifan daxue xuebao = Journal of East China Normal University in 2001. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Immune support

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Lion's Mane · 2001 · Journal Article · The Kaohsiung journal of medical sciences

Antimutagenicity of extracts of Hericium erinaceus.

Hericium erinaceus is valuable in the diet and in medical treatment. It contains water-soluble polysaccharides that have been found to enhance immunity and which show anti-artificial pulmonary metastatic tumor effects..

OncologyImmune supportRespiratory

High relevance

Yellow Morel · 2001 · Journal Article · Jilin nong ye da xue xue bao = Acta agriculturae universitatis jilinensis

Effects of GA and NAA on the growth of hyphae of Morchella esculenta

Metadata-grounded summary: This journal article indexes research on Morchella esculenta in Jilin nong ye da xue xue bao = Acta agriculturae universitatis jilinensis in 2001. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Immune support

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Maitake · 2001 · Journal Article · Cancer letters

Effects of maitake (Grifola frondosa) D-Fraction on the carcinoma angiogenesis.

We have reported that D-Fraction extracted from maitake (Grifola frondosa), activates immune competent cells, and indicates anti-tumor activities. The D-Fraction was observed to induce angiogenesis in vivo and to enhance the proliferation capability and migration capability of human vascular endothelial cell in vitro..

OncologyImmune support

High relevance

Enoki · 2001 · Journal Article · Life sciences

Isolation and characterization of velutin, a novel low-molecular-weight ribosome-inactivating protein from winter mushroom (Flammulina velutipes) fruiting bodies.

From the fruiting bodies of the edible mushroom Flammulina velutipes a single-chained ribosome inactivating protein with a molecular weight of 13.8 kDa was isolated with a procedure involving ion exchange chromatography on DEAE-cellulose and SP-Sepharose and affinity chromatography on Affi-gel blue gel..

Immune supportRespiratory

High relevance

Maitake · 2001 · Journal Article · Journal of experimental & clinical cancer research: CR

Nitric oxide-mediated antitumor activity induced by the extract from Grifola frondosa (Maitake mushroom) in a macrophage cell line, RAW264.7.

We have investigated D-fraction (MDF) extracted from Grifola frondosa (Maitake mushroom) on the inducible nitric oxide synthase (iNOS)-mediated nitric oxide (NO) production in RAW264.7 (RAW) cells, a murine monocyte/macrophage cell line, with special reference to antitumor activity of MDF against human….

OncologyImmune supportLiver support

High relevance

Enoki · 2000 · Journal Article · Sheng ming ke xue yan jiu

Conditions for protoplast formation of Flammulina velutipes

Metadata-grounded summary: This journal article indexes research on Flammulina velutipes in Sheng ming ke xue yan jiu in 2000. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Immune support

High relevance

Maitake · 2000 · Journal Article · Japanese journal of pharmacology

Effects of maitake (Grifola frondosa) polysaccharide on collagen-induced arthritis in mice.

We recently reported the anti-hepatitis effect of a polysaccharide, designated as the D-fraction, extracted from maitake. Its effect includes immuno-regulating activities.

OncologyImmune supportGut & microbiomeLiver support

High relevance

Maitake · 2000 · Journal Article · Wei sheng wu xue tong bao

Study on medium of submerged culture for Grifola frondosa

Each of 212 sera, taken from 129 patients with clinically established syphilis, was subjected to seven immunological tests. The tests were designed to detect both anti-lipoidal and anti-treponemal antibodies and to titrate antibody of both IgG and IgM molecular species..

Immune support

High relevance

Enoki · 1999 · Journal Article · Wei sheng wu xue tong bao

The physiological and biochemical characteristic in Flammulina velutipes Sing culture utilizing starch processing wastewater as medium

Metadata-grounded summary: This journal article indexes research on Flammulina velutipes in Wei sheng wu xue tong bao in 1999. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Immune support

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Enoki · 1998 · Journal Article · Wei sheng wu xue tong bao

Application of cluster analysis in crossbreeding in Flammulina velutipes

Metadata-grounded summary: This journal article indexes research on Flammulina velutipes in Wei sheng wu xue tong bao in 1998. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Immune support

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Enoki · 1997 · Journal Article · Edible Fungi of China

Biotransformation of selenium in hyphostroma of Flammulina velutipes NJ9601

Metadata-grounded summary: This journal article indexes research on Flammulina velutipes in Edible Fungi of China in 1997. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Immune support

High relevance

Enoki · 1997 · Journal Article · Wei sheng wu xue bao = Acta microbiologica Sinica

Studies on the conditions of quantity of bioconcentration Zn and the combined state of Zn by Flammulina velutipes

Metadata-grounded summary: This journal article indexes research on Flammulina velutipes in Wei sheng wu xue bao = Acta microbiologica Sinica in 1997. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Immune support

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Zhu Ling · 1997 · Journal Article · Zhongguo yao xue za zhi (Zhongguo yao xue hui: 1989)

The effects of Pseudomonas alba, Ganoderma lueidum etc. fermenting liquors in mycelia fermention of Polyporus umbellatus

Metadata-grounded summary: This journal article indexes research on Polyporus umbellatus in Zhongguo yao xue za zhi (Zhongguo yao xue hui: 1989) in 1997. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Immune support

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Enoki · 1997 · Journal Article · Nong ye sheng wu ji shu xue bao = Journal of agricultural biotechnology

Transformation of foreign DNA into protoplasts from Flammulina velutipes

Fifty-six male and 14 female leprosy patients, aged 11-62, were studied for cell-mediated immunity (CMI) and histocompatibility antigens. Healthy blood donors were used as normal controls.

OncologyImmune support

High relevance

Maitake · 1996 · Journal Article · Edible Fungi of China

Experiment on selection of stock culture medium for Grifola frondosa

Metadata-grounded summary: This journal article indexes research on Grifola frondosa in Edible Fungi of China in 1996. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Immune support

High relevance

Maitake · 1994 · Journal Article · Biological & pharmaceutical bulletin

Monoclonal antibody to proteoglycan derived from Grifola frondosa (Maitake).

A murine monoclonal antibody (MAb) was prepared by immunizing BALB/c mice with a proteoglycan fraction derived from Grifola frondosa (Maitake mushroom), followed by the hybridization of spleen cells with mouse myeloma cells..

Immune support

High relevance

Enoki · 1991 · Journal Article · Journal of food protection

Evaluation of the botulism hazard from vacuum-packaged enoki mushrooms (Flammulina velutipes)

Metadata-grounded summary: This journal article indexes research on Flammulina velutipes in Journal of food protection in 1991. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Immune support

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Wood Ear · 1981 · Journal Article · Carbohydrate research

Studies on interrelation of structure and antitumor effects of polysaccharides: antitumor action of periodate-modified, branched (1 goes to 3)-beta-D-glucan of Auricularia auricula-judae, and other polysaccharides containing (1 goes to 3)-glycosidic linkages.

Antitumor activities of two (1 goes to 3)-beta-D-glucans, isolated from the fruiting body of Auricularia auricula-judae ("kikurage", an edible mushroom), and other branched polysaccharides containing a backbone chain of (1 goes to 2)-alpha-D-glucosidic or (1 goes to 3)-alpha-D-mannosidic linkage [and their….

OncologyImmune support

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Almond Mushroom · n.d. · Research Article · journal metadata

Research advance in Agaricus blazei Murill

Metadata-grounded summary: This research article indexes research on Agaricus blazei. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Immune support

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Reishi · 2026 · Research Article · Food science & nutrition

A Triterpenoid-Enriched GLE70 Fraction From Ganoderma lingzhi Ameliorates Alcoholic Liver Disease via Multi-Target Regulation.

Alcoholic liver disease (ALD) arises from chronic alcohol consumption and progresses toward severe hepatic injury. Ganoderma lingzhi (G.

Immune supportMetabolic healthLiver support