MycoData

Following the idea of a circular bioeconomy, the use of side streams as substitutes for cultivation media (components) in bioprocesses would mean an enormous economic and ecological advantage..

High relevance

Reishi · 2024 · Research Article · Journal of fungi (Basel, Switzerland)

The Performance and Evolutionary Mechanism of Ganoderma lucidum in Enhancing Selenite Tolerance and Bioaccumulation.

BACKGROUND: Selenium (Se) pollution poses serious threats to terrestrial ecosystems. Mushrooms are important sources of Se with the potential for bioremediation.

Energy & fatigue

High relevance

Reishi · 2024 · Journal Article · Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire

The qualitative and quantitative analysis of Ganoderma lucidum spore powder chemical compounds as p38 MAPK inhibitors by the generation and verification of pharmacophore modelling

Ganoderma lucidum spore powder (GLSP), a high-value health food and medicine, has attracted widespread attention for its biological components and abundant pharmacological activities..

High relevance

Maitake · 2024 · Research Article · Life (Basel, Switzerland)

The Role of Grifola frondosa Polysaccharide in Preventing Skeletal Muscle Atrophy in Type 2 Diabetes Mellitus.

Type 2 diabetes mellitus (T2DM) is a burgeoning public health challenge worldwide. Individuals with T2DM are at increased risk for skeletal muscle atrophy, a serious complication that significantly compromises quality of life and for which effective prevention measures are currently inadequate..

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

High relevance

Shiitake · 2024 · Journal Article · Biological & pharmaceutical bulletin

The Tumor Growth Inhibitory Effect of a Standardized Extract of Cultured Lentinula edodes Mycelia Using Patient Derived Xenograft Model

Patient derived xenograft (PDX) is a powerful tool to confirm pharmacological efficacy in non-clinical studies for the development of various drugs including anti-cancer agents and therapeutic research. A standardized extract of cultured Lentinula edodes mycelia, a product name AHCC® is produced by Amino Up Co., Ltd..

OncologyImmune support

High relevance

Cordyceps · 2024 · Journal Article · Food chemistry

Tracing the geographical origin of endangered fungus Ophiocordyceps sinensis, especially from Nagqu, using UPLC-Q-TOF-MS.

Ophiocordyceps sinensis (OS), known as "soft gold", played an important role in local economic development. OS from different producing areas was difficult to be discriminated by the appearance.

High relevance

Turkey Tail · 2024 · Research Article · Materials (Basel, Switzerland)

Trametes versicolor Laccase-Based Magnetic Inorganic-Protein Hybrid Nanobiocatalyst for Efficient Decolorization of Dyes in the Presence of Inhibitors.

In the present investigation, an ecofriendly magnetic inorganic-protein hybrid system-based enzyme immobilization was developed using partially purified laccase from Trametes versicolor (TvLac), Fe3O4 nanoparticles, and manganese (Mn), and was successfully applied for synthetic dye decolorization in the presence of….

High relevance

Oyster Mushroom · 2024 · Journal Article · Fungal biology

Transcription factor Pofst3 regulates Pleurotus ostreatus development by targeting multiple biological pathways.

Pleurotus ostreatus is a popular edible mushroom cultivated worldwide. However, the mechanism of P.

Metabolic health

High relevance

Shiitake · 2024 · Research Article · Foods (Basel, Switzerland)

Transcriptome Reveals the Key Genes Related to the Metabolism of Volatile Sulfur-Containing Compounds in Lentinula edodes Mycelium.

Lentinula edodes (L. edodes) is a globally popular edible mushroom because of its characteristic sulfur-containing flavor compounds.

High relevance

Shiitake · 2024 · Journal Article · Journal of agricultural and food chemistry

Transcriptomic Communication between Nucleus and Mitochondria during the Browning Process of Lentinula edodes.

To explore the reason for cytoplasmic replacement's significant effect on browning, transcriptomic data of nuclear (N) and mitochondrial (M) mRNAs and long noncoding RNAs (lncRNAs) in L808 and two cytoplasmic hybrids (cybrids) (L808-A2 and L808-B) of Lentinula edodes at three different culturing times (80, 100, and….

Energy & fatigueMetabolic healthSkin & hydration

High relevance

Snow Fungus · 2024 · Research Article · Nutrients

Tremella fuciformis Berk Alleviated Atherosclerosis Symptoms via Nuclear Factor-Kappa B-Mediated Inflammatory Response in ApoE-/- Mice.

BACKGROUND: Atherosclerosis, a persistent inflammatory disease marked by the presence of atherosclerotic plaques or fibrous plaques, is a significant contributor to the onset of the development of cardiovascular disease..

Immune supportGut & microbiome

High relevance

Reishi · 2024 · Journal Article · Phytochemistry

Triterpenes from antler-shaped fruiting body of Ganoderma lucidum and their hepatoprotective activities.

Seven previously undescribed triterpenes (1-7), as well as one triterpene (8) previously described as a synthetic product, were isolated from the antler-shaped fruiting body of Ganoderma lucidum. Their structures were established based on comprehensive spectroscopy analysis..

OncologyLiver support

High relevance

Reishi · 2024 · Research Article · Frontiers in pharmacology

Triterpenoids from Ganoderma lucidum inhibit cytochrome P450 enzymes interfering with the metabolic process of specific clinical drugs.

BACKGROUND: Ganoderma lucidum (G. lucidum), which possesses various biological effects, has been widely used as traditional medicine and functional food in Asian countries, especially China.

Metabolic health

High relevance

Almond Mushroom · 2024 · Journal Article · International journal of biological macromolecules

Troxerutin associated with Agaricus blazei Murill polysaccharides in films improves full-thickness wound healing.

The present study aimed to associate troxerutin (TRX) with polysaccharides from Agaricus blazei Murill mushroom (PolyAb) in alginate/PVA films and evaluate their effect on wound healing..

Immune supportSkin & hydration

High relevance

Lion's Mane · 2024 · Research Article · Food chemistry: X

Ultrasound-assisted enzymatic extraction of soluble dietary Fiber from Hericium erinaceus and its in vitro lipid-lowering effect.

Dietary fiber (DF) is an important active polysaccharide in Hericium erinaceus. Obesity can lead to a wide range of diseases.

Immune supportMetabolic health

High relevance

Oyster Mushroom · 2024 · Journal Article · Current microbiology

Use of Ozone as a Substrate Treatment for the Control of Trichoderma in the Production of Pleurotus ostreatus.

Pleurotus ostreatus is one of the most widely cultivated species in the world. It can be produced in many lignocellulosic substrates after carrying out a treatment to eliminate competing microorganisms.

High relevance

Oyster Mushroom · 2024 · Journal Article · International journal of food microbiology

Using pre-fermented sugar beet pulp as a growth medium to produce Pleurotus ostreatus mycelium for meat alternatives.

This study aimed to determine the compatibility of pre-fermented sugar beet pulp to support the growth of Pleurotus ostreatus mycelium in submerged fermentation. The goal was to create a meat alternative based on mycelial-fermented pulp..

Gut & microbiome

High relevance

Reishi · 2024 · Journal Article · Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire

Valorization of brewer's spent grains through Ganoderma lucidum cultivation: Functional food ingredients and bread prototypes

Brewer spent grain (BSG) is the primary by-product of beer production, representing 85% of total waste in this industry. This study aimed to valorize BSG by incorporating it into the cultivation medium for Ganoderma lucidum to develop functional food ingredients with enhanced techno-functional and nutritional….

High relevance

Reishi · 2023 · Review · Chinese medicine

A review of anti-tumour effects of Ganoderma lucidum in gastrointestinal cancer.

Gastrointestinal (GI) cancer is the most common cancer in the world and one of the main causes of cancer-related death. Clinically, surgical excision and chemotherapy are the main treatment methods for GI cancer, which is unfortunately accompanied with serious adverse reactions and drug toxicity, bringing irreversible….

OncologyImmune supportGut & microbiome

High relevance

Reishi · 2023 · Review · International journal of biological macromolecules

A review of Ganoderma lucidum polysaccharides: Health benefit, structure-activity relationship, modification, and nanoparticle encapsulation.

Ganoderma lucidum polysaccharides possess unique functional properties. Various processing technologies have been used to produce and modify G.

Immune supportLiver support

High relevance

Niu-Chang-Chih · 2023 · Review · Journal of ethnopharmacology

A review on the protective effect of active components in Antrodia camphorata against alcoholic liver injury.

ETHNOPHARMACOLOGICAL RELEVANCE: Antrodia camphorata is a genus of wood-rot basidiomycete in the family Fomitopsidaceae. It is a valuable medicinal fungus in China that contains more than 78 kinds of active compounds.

Immune supportGut & microbiomeLiver support

High relevance

Oyster Mushroom · 2023 · Review · Journal of applied microbiology

Bacterial interactions with the mycelium of the cultivated edible mushrooms Agaricus bisporus and Pleurotus ostreatus.

The cultivated edible mushrooms Agaricus bisporus and Pleurotus ostreatus are valuable food crops and an important source of human nutrition. Agaricus bisporus is the dominant cultivated species in the western hemisphere and in Australia, while in Asian countries P.

High relevance

Reishi · 2023 · Review · Journal of research in medical sciences: the official journal of Isfahan University of Medical Sciences

Effect of Ganoderma lucidum on serum lipid profiles: A systematic review and meta-analysis on animal studies.

BACKGROUND: Ganoderma lucidum (G. lucidum) is one of the most popular edible mushrooms in the world which has various pharmacological components.

Metabolic health

High relevance

Reishi · 2023 · Review · Cancer cell international

Exploring the anti-cancer potential of Ganoderma lucidum polysaccharides (GLPs) and their versatile role in enhancing drug delivery systems: a multifaceted approach to combat cancer.

There has been a growing global interest in the potential health benefits of edible natural bioactive products in recent years. Ganoderma lucidum, a medicinal mushroom, has gained attention for its decadent array of therapeutic and pharmaceutical compounds.

OncologyImmune supportEnergy & fatigueLiver support

High relevance

Reishi · 2023 · Review · Foods (Basel, Switzerland)

Exploring the Potential Medicinal Benefits of Ganoderma lucidum: From Metabolic Disorders to Coronavirus Infections.

Ganoderma lucidum is a medicinal mushroom that has been traditionally used in Chinese medicine for centuries. It has been found to have a wide range of medicinal properties, including antioxidant, anti-inflammatory, and immune-boosting effects.

Immune supportMetabolic healthRespiratory

High relevance

Yellow Morel · 2023 · Review · International journal of medicinal mushrooms

Food and Antioxidant Supplements with Therapeutic Properties of Morchella esculenta (Ascomycetes): A Review.

Morchella esculenta, commonly known as yellow morels, is an edible and medicinal mushroom popular worldwide for its unique flavor and culinary purposes. The traditional medical system effectively uses morels against infertility, fatigue, cancer, muscular pain, cough, and cold.

OncologyImmune supportEnergy & fatigueMetabolic health

High relevance

Reishi · 2023 · Review · Nutrients

Ganoderma lucidum: Novel Insight into Hepatoprotective Potential with Mechanisms of Action.

Ganoderma lucidum (G. lucidum) has been widely used for its health benefits as an edible and traditional medicinal mushroom for thousands of years in Asian countries.

OncologyImmune supportLiver supportRespiratory

High relevance

Lion's Mane · 2023 · Review · Journal of fungi (Basel, Switzerland)

Hericium erinaceus in Neurodegenerative Diseases: From Bench to Bedside and Beyond, How Far from the Shoreline?

A growing number of studies is focusing on the pharmacology and feasibility of bioactive compounds as a novel valuable approach to target a variety of human diseases related to neurological degeneration..

Cognition & nerves

High relevance

Lion's Mane · 2023 · Review · World journal of gastroenterology

Hericium erinaceus, a medicinal fungus with a centuries-old history: Evidence in gastrointestinal diseases.

Hericium erinaceus is an edible and medicinal mushroom commonly used in traditional Chinese medicine for centuries. Several studies have highlighted its therapeutic potential for gastrointestinal disorders such as gastritis and inflammatory bowel diseases..

OncologyImmune supportGut & microbiome

High relevance

Snow Fungus · 2023 · Review · Genome biology

Meiosis in an asymmetric dikaryotic genome of Tremella fuciformis Tr01 facilitates new chromosome formation.

BACKGROUND: The dikaryotic stage dominates most of the life cycle in basidiomycetes, and each cell carries two different haploid nuclei. Accurate phasing of these two nuclear genomes and their interactions have long been of interest..

High relevance

Oyster Mushroom · 2023 · Review · Foods (Basel, Switzerland)

Modulation of the Gut Microbiota with Prebiotics and Antimicrobial Agents from Pleurotus ostreatus Mushroom.

Pleurotus ostreatus (Jacq. ex Fr.) P.

Immune supportGut & microbiomeRespiratory

High relevance

Reishi · 2023 · Review · Antioxidants (Basel, Switzerland)

Natural Bio-Compounds from Ganoderma lucidum and Their Beneficial Biological Actions for Anticancer Application: A Review.

Ganoderma lucidum (G. lucidum) has been known for many centuries in Asian countries under different names, varying depending on the country.

OncologyImmune support

High relevance

Lion's Mane · 2023 · Review · International journal of molecular sciences

Neurotrophic and Neuroprotective Effects of Hericium erinaceus.

Hericium erinaceus is a valuable mushroom known for its strong bioactive properties. It shows promising potential as an excellent neuroprotective agent, capable of stimulating nerve growth factor release, regulating inflammatory processes, reducing oxidative stress, and safeguarding nerve cells from apoptosis..

OncologyImmune supportCognition & nerves

High relevance

Reishi · 2023 · Review · Cureus

Pharmacological Activities and Safety of Ganoderma lucidum Spores: A Systematic Review.

Ganoderma lucidum is traditionally used to prevent and treat some diseases such as liver disorders, hypertension, insomnia, diabetes, and cancer. G.

OncologyImmune supportMetabolic healthLiver support

High relevance

Reishi · 2023 · Review · Molecules (Basel, Switzerland)

Potential Anti-Rheumatoid Arthritis Activities and Mechanisms of Ganoderma lucidum Polysaccharides.

Rheumatoid arthritis (RA) is a chronic and autoimmune disease characterized by inflammation, autoimmune dysfunction, and cartilage and bone destruction. In this review, we summarized the available reports on the protective effects of Ganoderma lucidum polysaccharides (GLP) on RA in terms of anti-inflammatory,….

Immune support

High relevance

Snow Fungus · 2023 · Review · Archives of dermatological research

The potential cutaneous benefits of Tremella fuciformis.

Tremella fuciformis, also known as snow mushroom, is an edible mushroom that has historically been popular in herbal and Asian medicine and cuisine. The main polysaccharide ingredients have been extracted and used as treatment in a variety of conditions, demonstrating positive effects in a range of biological….

OncologyImmune supportCognition & nervesMetabolic health

High relevance

Reishi · 2022 · Review · Frontiers in pharmacology

Antioxidant, antibacterial, antitumor, antifungal, antiviral, anti-inflammatory, and nevro-protective activity of Ganoderma lucidum: An overview.

Ganoderma lucidum is a very medicinal mushroom that has been utilized in Oriental medicine for many years. It has a wide range of pharmacological and therapeutic properties, and has been used for many years as a health promoter..

OncologyImmune supportRespiratory

High relevance

Yellow Morel · 2022 · Review · Food research international (Ottawa, Ont.)

Mycochemical profile and health-promoting effects of morel mushroom Morchella esculenta (L.) - A review.

Mushrooms have been well known for centuries in traditional Chinese medicine for their medicinal properties. Morchella esculenta (L.) Pers.

OncologyImmune supportMetabolic healthLiver support

High relevance

Enoki · 2021 · Review · International journal of biological macromolecules

Advances in the extraction, purification, structural-property relationships and bioactive molecular mechanism of Flammulina velutipes polysaccharides: A review.

With the further research in recent years, Flammulina velutipes (F. velutipes), an edible mushroom, has great application value in many fields.

OncologyImmune supportMetabolic healthLiver support

High relevance

Chaga · 2021 · Review · Journal of ethnopharmacology

Deciphering the antitumoral potential of the bioactive metabolites from medicinal mushroom Inonotus obliquus.

ETHNOPHARMACOLOGICAL RELEVANCE: The crude extracts of the medicinal mushroom Inonotus obliquus have been used as an effective traditional medicine to treat malicious tumors, gastritis, gastric ulcers, and other inflammatory conditions in Russia and most Baltic countries..

OncologyImmune supportEnergy & fatigueGut & microbiome

High relevance

Chaga · 2021 · Review · Journal of traditional and complementary medicine

Inonotus obliquus - from folk medicine to clinical use.

The Inonotus obliquus (I. obliquus) mushroom was traditionally used to treat various gastrointestinal diseases.

OncologyImmune supportEnergy & fatigueMetabolic health

High relevance

Cordyceps · 2021 · Review Article · 3 Biotech

Novel formulation development from Ophiocordyceps sinensis (Berk.) for management of high-altitude maladies.

Ophiocordyceps sinensis (Berk.) is a fungus closely related to medicinal mushroom, which belongs to the family Ophiocordycipitaceae. It is a well-known and rich herbal source of bioactive active constituents.

OncologyImmune supportMetabolic healthRespiratory

High relevance

Zhu Ling · 2021 · Review · International journal of biological macromolecules

Polysaccharides from Polyporus umbellatus: A review on their extraction, modification, structure, and bioactivities.

Polyporus umbellatus (Pers.) Fries, a well-known medicinal fungus, has been reported to exhibit important functions of diuresis and dampness infiltration in traditional Chinese Medicine. Accumulating evidences have demonstrated that the P..

OncologyImmune supportLiver supportSkin & hydration

High relevance

Yellow Morel · 2021 · Review · Applied biochemistry and biotechnology

Recent Advances on Bioactive Ingredients of Morchella esculenta.

Morchella esculenta (M. esculenta) is a delicious edible mushroom prized for its special flavor and strong health promoting abilities.

OncologyImmune supportMetabolic health

High relevance

Wood Ear · 2021 · Review · Journal of agricultural and food chemistry

Review on Auricularia auricula-judae as a Functional Food: Growth, Chemical Composition, and Biological Activities.

Although the application of Auricularia auricula-judae (AAJ) for health purposes has a long tradition in Asia, there is a lack of research on the functional nutrition of AAJ; the current research focused on polysaccharides has been too unitary compared to other mushrooms in recent years..

Immune support

High relevance

Turkey Tail · 2021 · Review · Acta pharmaceutica (Zagreb, Croatia)

The use of Hericium erinaceus and Trametes versicolor extracts in supportive treatment in oncology.

Substances available in nature with potential therapeutic effects are the subject of research that raises tremendous hopes for new challenges in medicine. Fungi are the most common organisms in the ecosystem and the most interesting in this respect..

OncologyImmune supportCognition & nerves

High relevance

Turkey Tail · 2021 · Review · Bioresource technology

Trametes versicolor in lignocellulose-based bioeconomy: State of the art, challenges and opportunities.

Although Trametes versicolor is one of the most investigated white-rot fungi, the industrial application of this fungus and its metabolites is still far from reaching its full potential. This review aims to highlight the opportunities and challenges for the industrial use of T..

High relevance

Cordyceps · 2019 · Review · Critical reviews in biotechnology

A breakthrough in the artificial cultivation of Chinese cordyceps on a large-scale and its impact on science, the economy, and industry.

Chinese cordyceps, an entity of the Chinese caterpillar fungus (Ophiocordyceps sinensis, syn. Cordyceps sinensis) that parasitizes ghost moth larvae, is one of the best known traditional Chinese medicines and is found exclusively on the Tibetan Plateau with limited natural resources.

High relevance

Turkey Tail · 2014 · Randomized Controlled Trial · International journal of medicinal mushrooms

Control of oral human papillomavirus (HPV) by medicinal mushrooms, Trametes versicolor and Ganoderma lucidum: a preliminary clinical trial.

This preliminary randomized study investigated the efficacy of medicinal mushrooms, Trametes versicolor (TV), Ganoderma lucidum (GL), and Laetiporus sulphureus (LS), on the clearance of oral human papillomavirus (HPV, serotypes 16 and 18)..

Respiratory

High relevance

Turkey Tail · 2014 · Randomized Controlled Trial · Gut microbes

Effects of polysaccharopeptide from Trametes versicolor and amoxicillin on the gut microbiome of healthy volunteers: a randomized clinical trial.

BACKGROUND: Interactions between the microbial flora of the intestine and the human host play a critical role inmaintaining intestinal health and in the pathophysiology of a wide variety of disorders such as antibiotic associated diarrhea, Clostridium difficile infection, and inflammatory bowel disease..

Immune supportGut & microbiome