MycoData

Oyster Mushroom · 2025 · Research Support, Non U.S. Gov'T · Applied and environmental microbiology

Establishing microbial communities to promote the growth of Pleurotus ostreatus through a top-down approach is hindered by the dominance of antagonistic interactions.

Few attempts have been made to examine the diversity and functions that characterize microbial communities compatible with and beneficial to the biotechnologically relevant mushroom Pleurotus ostreatus..

Energy & fatigueMetabolic healthRespiratory

Cordyceps · 2025 · Data Paper · Data in brief

Metabolomic data on molecular weight fractions of the cultivated fruiting body of Ophiocordyceps sinensis and their pharmacological effects on airway tissues.

Ophiocordyceps sinensis is a medicinal mushroom that has been traditionally used for promoting respiratory health and addressing diverse therapeutic needs. The data in this article provides insights into the metabolic profile of the cultivated fruiting body of Ophiocordyceps sinensis (xOs™) across different molecular….

Reishi · 2025 · Research Support, Non U.S. Gov'T · Scientific reports

Selected nutritional properties of Ganoderma lucidum and substrate degradation during multi-cycle reuse with hazelnut branch waste.

In this study, the effects of reusing spent Reishi (Ganoderma lucidum) (Curtis) P. Karst mushroom substrate (SMS) from cultivation-by mixing it with hazelnut branch-based substrate (HB) at different ratios (HB100%, HB75%:SMS25%, HB50%:SMS50%, HB25%:SMS75%, SMS100%)-on the yield, quality, and nutritional composition of….

Reishi · 2025 · Research Support, Non U.S. Gov'T · Applied and environmental microbiology

The APSES transcription factor Swi6B upregulates CATALASE 1 transcription to enhance oxidative stress tolerance of Ganoderma lucidum.

As sessile organisms, fungi often encounter various stresses throughout their lifespan, resulting in the overproduction of reactive oxygen species, which impedes the normal growth of fungi. Previously, we revealed that the Swi6B transcription factor is involved in the stress tolerance of Ganoderma lucidum..

Oyster Mushroom · 2025 · Research Support, Non U.S. Gov'T · Mycologia

The biosynthesis and impacts of cytokinins on growth of the oyster mushroom, Pleurotus ostreatus.

While a lot is known about cytokinins (CKs) and their actions at the molecular and cellular levels in plants, much less is known about the function of CKs in other kingdoms such as fungi..

Energy & fatigueGut & microbiomeLiver supportRespiratory

Cordyceps · 2024 · Research Support, Non U.S. Gov'T · Toxins

Functional Characterization and Toxicological Study of Cordyceps militaris in Weaned Pigs.

Cordyceps militaris (CM), a well-known parasitic fungus that grows on the larvae of Lepidoptera, has a variety of pharmacological activities. However, little is known about its safe dosage for animals, including pigs..

Immune supportEnergy & fatigue

Cordyceps · 2024 · Research Support, Non U.S. Gov'T · Developmental and comparative immunology

Histopathological observations and comparative transcriptome analysis of Ophiocordyceps sinensis infection of Hepialus xiaojinensis in the early stage.

Hepialus xiaojinensis is a Lepidopteran insect and one of the hosts for the artificial cultivation of Cordyceps. Ophiocordyceps sinensis can infect and coexist with H.

Oyster Mushroom · 2023 · Research Article · Frontiers in microbiology

A lectin gene is involved in the defense of Pleurotus ostreatus against the mite predator Tyrophagus putrescentiae.

The storage mite, Tyrophagus putrescentiae, found worldwide in many habitats, is an important pest of edible mushrooms. Excessive chemical spraying for pest control has been linked to environmental pollution, health risks, insecticide resistance development, and food safety..

Energy & fatigueMetabolic healthSkin & hydration

Reishi · 2023 · Journal Article · Journal of ethnopharmacology

A proteoglycan isolated from Ganoderma lucidum attenuates diabetic kidney disease by inhibiting oxidative stress-induced renal fibrosis both in vitro and in vivo.

ETHNOPHARMACOLOGICAL RELEVANCE: Ganoderma lucidum (G. lucidum) was regarded as "miraculous herb" by the Chinese and recorded detailly in the "Shen Nong Ben Cao Jing" as a tonic to improve health and prolong life..

Energy & fatigueMetabolic healthSkin & hydration

Oyster Mushroom · 2023 · Journal Article · Food research international (Ottawa, Ont.)

Activation of mycelial defense mechanisms in the oyster mushroom Pleurotus ostreatus induced by Tyrophagus putrescentiae

Fungal chemicals are vital in processes recognizing damage- and microbe-associated molecules (DAMPs/MAMPs) that trigger defense responses in fungi. Pleurotus ostreatus is a widely cultivated edible fungus that is prone to attack from fungivorous insects and mites.

Chaga · 2023 · Research Article · Frontiers in pharmacology

Anti-cancer activity of Chaga mushroom (Inonotus obliquus) against dog bladder cancer organoids.

Despite its disadvantages, chemotherapy is still commonly used for the treatment of bladder cancer (BC). Developing natural supplements that can target cancer stem cells (CSCs) which cause drug resistance and distant metastasis is necessary..

OncologyEnergy & fatigue

Immune supportCognition & nervesEnergy & fatigue

King Oyster · 2023 · Research Article · Molecules (Basel, Switzerland)

Antioxidant Activity of Polysaccharides from the Edible Mushroom Pleurotus eryngii.

In this study the antioxidant and neuroprotective activity of an enriched polysaccharide fraction (EPF) obtained from the fruiting body of cultivated P. eryngii was evaluated.

Immune supportEnergy & fatigue

Enoki · 2023 · Research Article · IET nanobiotechnology

Biosynthesis of gold nanoparticles in the fruiting body of enoki mushrooms (Flammulina velutipes) under Pb2+ induction.

Fungi can produce many compounds, such as proteins, enzymes, amino acids, and polysaccharides, which are internalised and enriched for metals, and are widely used as reducing and stabilising agents for the biosynthesis of gold nanoparticles (Au NPs)..

OncologyImmune supportEnergy & fatigueMetabolic health

Cordyceps · 2023 · Research Article · Chinese medicine

Cordycepin from Cordyceps militaris ameliorates diabetic nephropathy via the miR-193b-5p/MCL-1 axis.

BACKGROUND: Diabetic nephropathy (DN) is a chronic kidney disease that develops in patients with diabetes mellitus. Cordycepin (CRD), a secondary metabolite produced by Cordyceps militaris, has a variety of bioactive properties..

Immune supportCognition & nervesEnergy & fatigue

Cordyceps · 2023 · Journal Article · International journal of biological macromolecules

Cordyceps militaris acidic polysaccharides improve learning and memory impairment in mice with exercise fatigue through the PI3K/NRF2/HO-1 signalling pathway.

Excessive exercise leads to body fatigue and destroys the balance of the oxidation/oxidation resistance system in the body, thus damaging the central nervous system and reducing learning and memory ability. Nrf2 is an important transcription factor that regulates the cell oxidative stress response..

OncologyEnergy & fatigueGut & microbiome

Cordyceps · 2023 · Journal Article · Heliyon

Development of an efficient method for separation and purification of cordycepin from liquid fermentation of Cordyceps militaris and analysis of cordycepin antitumor activity

Cordycepin (3 ′-deoxyadenosine) is the main active component of Cordyceps militaris, which is a chemical marker for quality detection of Cordyceps militaris and has important medicinal development value. Existing methods for obtaining cordycepin are complex and costly..

OncologyEnergy & fatigueGut & microbiome

Cordyceps · 2023 · Research Article · Heliyon

Development of an efficient method for separation and purification of cordycepin from liquid fermentation of Cordyceps militaris and analysis of cordycepin antitumor activity.

Cordycepin (3 '-deoxyadenosine) is the main active component of Cordyceps militaris, which is a chemical marker for quality detection of Cordyceps militaris and has important medicinal development value. Existing methods for obtaining cordycepin are complex and costly..

Immune supportEnergy & fatigueMetabolic healthLiver support

Mesima · 2023 · Journal Article · Journal of trace elements in medicine and biology: organ of the Society for Minerals and Trace Elements (GMS)

Dietary supplementation with selenium polysaccharide from selenium-enriched Phellinus linteus improves antioxidant capacity, immunity and production performance of laying hens.

BACKGROUND: Selenium (Se) plays a beneficial role in the physiological function of humans and animals. Selenium polysaccharide, improving enzyme activity and regulating immunity, is the extraction from selenium-rich plants or mushrooms..

Immune supportCognition & nervesEnergy & fatigueGut & microbiome

Cordyceps · 2023 · Research Article · Microbiology spectrum

Dual Transcriptomics Reveals Interspecific Interactions between the Mycoparasite Calcarisporium cordycipiticola and Its Host Cordyceps militaris.

Calcarisporium cordycipiticola is a mycoparasite of the edible fungus Cordyceps militaris, and mycoparasitism causes devastating diseases of mushrooms. In this study, dual-transcriptomic analysis was performed to reveal interspecific interactions between the mycoparasite C.

Energy & fatigueSkin & hydration

Cordyceps · 2023 · Journal Article · International journal of medicinal mushrooms

Effects of Exogenous Lanthanum Nitrate on the Active Substance Content and Antioxidant Activity of Caterpillar Medicinal Mushroom Cordyceps militaris (Ascomycetes).

Cordyceps militaris is a medicinal and edible mushroom. Researchers often add exogenous substances to the culture medium to increase the active substance content in C.

Reishi · 2023 · Research Article · Frontiers in nutrition

Effects of Ganoderma lucidum polysaccharide peptide ameliorating cyclophosphamide-induced immune dysfunctions based on metabolomics analysis.

Ganoderma lucidum polysaccharide peptide (GLPP) is one of the most abundant constituents of Ganoderma lucidum (G. lucidum), with a wide range of functional activities.

Energy & fatigueMetabolic healthLiver support

Reishi · 2023 · Journal Article · Applied microbiology and biotechnology

Effects of glutamate oxaloacetate transaminase on reactive oxygen species in Ganoderma lucidum.

Nitrogen metabolism can regulate mycelial growth and secondary metabolism in Ganoderma lucidum. As an important enzyme in intracellular amino acid metabolism, glutamate oxaloacetate transaminase (GOT) has many physiological functions in animals and plants, but its function in fungi has been less studied..

OncologyImmune supportEnergy & fatigueMetabolic health

Enoki · 2023 · Journal Article · The Science of the total environment

Flammulina velutipes polysaccharide counteracts cadmium-induced gut injury in mice via modulating gut inflammation, gut microbiota and intestinal barrier.

Cadmium (Cd), as Group I carcinogen, can induce damage to various organs including the gut. It is of great importance to meet the rising demand for effective therapies against Cd-induced damage and investigate the mechanism..

Immune supportCognition & nervesEnergy & fatigue

Reishi · 2023 · Journal Article · Comparative biochemistry and physiology. Toxicology & pharmacology: CBP

Ganoderma lucidum polysaccharide alleviates Cd toxicity in common carp (Cyprinus carpio): Neuropeptide, growth performance and lipid accumulation.

Cadmium (Cd) is the most common heavy metal and is easily detected in aquatic environments on a global scale. Common carp (Cyprinus carpio) is a common cultural species in aquaculture.

OncologyImmune supportEnergy & fatigue

Reishi · 2023 · Journal Article · South African journal of botany

GC–MS, molecular identification, proximate and mineral content composition of two wild mushrooms (Ganoderma lucidum, Pleurotus ostreatus) from Gilgit Baltistan Northern area of Pakistan

For a very long time, diverse civilizations all over the world have recognised that mushrooms, which are the fruiting bodies of fungi, have medicinal characteristics and used to treat different kinds of human diseases..

Cordyceps · 2023 · Journal Article · Bioresource technology

High-level production of cordycepin by the xylose-utilising Cordyceps militaris strain 147 in an optimised medium.

Cordycepin is an important active metabolite of Cordyceps militaris. Xylose, an attractive feedstock for producing chemicals through microbial fermentation, cannot be effectively utilised by many reported C.

King Oyster · 2023 · Research Article · Frontiers in nutrition

Hypolipidemic mechanism of Pleurotus eryngii polysaccharides in high-fat diet-induced obese mice based on metabolomics.

OBJECTIVE: In this study, the structure of Pleurotus eryngii polysaccharides (PEPs) was characterized, and the mechanism of PEP on obesity and hyperlipidemia induced by high-fat diet was evaluated by metabonomic analysis..

OncologyEnergy & fatigueGut & microbiomeLiver support

King Oyster · 2023 · Journal Article · Journal of the science of food and agriculture

Identification and preparation of selenium-containing peptides from selenium-enriched Pleurotus eryngii and their protective effect on lead-induced oxidative damage in NCTC1469 hepatocytes.

BACKGROUND: Lead (Pb) is a highly toxic and persistent substance that easily accumulates in living organisms, eliciting cellular toxicity and oxidative stress. Some selenium-containing proteins and peptides prepared from plant extracts are beneficial for protecting the body's health and resisting external….

OncologyEnergy & fatigueGut & microbiomeLiver support

King Oyster · 2023 · Journal Article · Journal of the science of food and agriculture

Identification and preparation of selenium‐containing peptides from selenium‐enriched Pleurotus eryngii and their protective effect on lead‐induced oxidative damage in NCTC1469 hepatocytes

BACKGROUND: Lead (Pb) is a highly toxic and persistent substance that easily accumulates in living organisms, eliciting cellular toxicity and oxidative stress. Some selenium‐containing proteins and peptides prepared from plant extracts are beneficial for protecting the body's health and resisting external….

Cognition & nervesEnergy & fatigue

Cordyceps · 2023 · Research Article · 3 Biotech

Identification of potential inhibitors against Alzheimer-related proteins in Cordyceps militaris ethanol extract: experimental evidence and computational analyses.

UNLABELLED: Laboratory experiments were carried out to identify the chemical composition of Cordyceps militaris and reveal the first evidence of their Alzheimer-related potential. Liquid chromatography-mass spectrometry analysis identified 21 bioactive compounds in the ethanol extract (1-21)..

Cognition & nervesEnergy & fatigue

Reishi · 2023 · Research Article · Aging medicine (Milton (N.S.W))

Identification of potential neuroprotective compound from Ganoderma lucidum extract targeting microtubule affinity regulation kinase 4 involved in Alzheimer's disease through molecular dynamics simulation and MMGBSA.

OBJECTIVE: Alzheimer's disease (AD) is one of the most prevalent neurological ailments, affecting around 50 million individuals globally. The condition is characterized by nerve cell damage due to the formation of amyloid-beta plaques and neurofibrillary tangles..

Cordyceps · 2023 · Journal Article · Food Chemistry

In-situ and real-time monitoring of two-stage enzymatic preparation of ACE inhibitory peptides from Cordyceps militaris medium residues by ultrasonic-assisted pretreatment

A protocol for the preparation of angiotensin-Ⅰ-converting enzyme (ACE) inhibitory peptides from Cordyceps militaris medium residues (CMMR) was established by two-stage enzymatic hydrolysis (amylase and protease)..

Cordyceps · 2023 · Journal Article · Food chemistry

In-situ and real-time monitoring of two-stage enzymatic preparation of ACE inhibitory peptides from Cordyceps militaris medium residues by ultrasonic-assisted pretreatment.

Reishi · 2023 · Journal Article · International journal of biological macromolecules

Inhibition of intrarenal PRR-RAS pathway by Ganoderma lucidum polysaccharide peptides in proteinuric nephropathy.

Excessive proteinuria leads to renal dysfunction and damage. Ganoderma lucidum polysaccharide peptide (GL-PP) and Ganoderma lucidum polysaccharide peptide 2 (GL-PP2) are biologically active compounds extracted from Ganoderma lucidum..

Cordyceps · 2023 · Research Article · Frontiers in microbiology

Integrated enzymes activity and transcriptome reveal the effect of exogenous melatonin on the strain degeneration of Cordyceps militaris.

As a valuable medicinal and edible fungus, Cordyceps militaris has been industrialized with broad development prospects. It contains a lot of bioactive compounds that are beneficial to our health..

OncologyImmune supportEnergy & fatigueRespiratory

King Oyster · 2023 · Journal Article · International journal of medicinal mushrooms

King Oyster Mushroom, Pleurotus eryngii (Agaricomycetes), Extract Can Attenuate Doxorubicin-Induced Lung Damage by Inhibiting Oxidative Stress in Rats.

Doxorubicin (DOX), a broad spectrum chemotherapeutic, has toxic effects on healthy tissues. Mitochondrial processes and oxidative stress act in the DOX-induced toxicity, therefore antioxidant therapies are widely used..

Immune supportEnergy & fatigue

Oyster Mushroom · 2023 · Journal Article · Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire

Metabolites profiling of protein enriched oyster mushroom (Pleurotus ostreatus (Jacq.) P. Kumm.) grown on oil palm empty fruit bunch substrate

This study aimed to compare the nutritional composition and metabolites profiles of the Pleurotus ostreatus oyster mushroom grown on oil palm empty fruit bunch (EFB) and rubber wood sawdust (RWS) substrates..

Shiitake · 2023 · Journal Article · Journal of food composition and analysis

Model optimization for geographical discrimination of Lentinula edodes based stable isotopes and multi-elements in China

Geographical origin discrimination of agricultural products is essential to guarantee food safety and fair trade. Lentinula edodes (Shiitake mushroom) samples cultivated in three major production regions in China were characterized using stable isotopes (δ¹³C, δ²H, δ¹⁸O, δ¹⁵N, and δ³⁴S) and elemental contents (%C, %N,….

Energy & fatigueLiver support

Reishi · 2023 · Journal Article · Phytochemical analysis: PCA

Modeling and optimization of the protocol of complex chromatography separation of cyclooxygenase-2 inhibitors from Ganoderma lucidum spore.

INTRODUCTION: The spores of the medicinal fungus Ganoderma lucidum possess hepatoprotective properties. The main components, triterpenes, are particularly beneficial, making the screening and preparation of active triterpenes from Ganoderma lucidum significant..

Energy & fatigueMetabolic health

Turkey Tail · 2023 · Research Article · Frontiers in microbiology

Modeling the microbial pretreatment of camelina straw and switchgrass by Trametes versicolor and Phanerochaete chrysosporium via solid-state fermentation process: A growth kinetic sub-model in the context of biomass-based biorefineries.

Advancing microbial pretreatment of lignocellulose has the potential not only to reduce the carbon footprint and environmental impacts of the pretreatment processes from cradle-to-grave, but also increase biomass valorization, support agricultural growers, and boost the bioeconomy..

Cordyceps · 2023 · Journal Article · Bioresource technology

Multi-omics analysis unravels positive effect of rotenone on the cordycepin biosynthesis in submerged fermentation of Cordyceps militaris.

Cordycepin is the key pharmacologically active compound of Cordyceps militaris, and various fermentation strategies have been developed to increase cordycepin production. This study aimed to investigate the effect of rotenone on cordycepin biosynthesis in submerged fermentation of C..

Oyster Mushroom · 2023 · Research Article · Heliyon

Performance of oyster mushroom (Pleurotus ostreatus) on paddy straw, water hyacinth and their combinations.

This study aimed to investigate the performance of oyster mushrooms on different substrate combinations, including rice straw alone, rice straw and water hyacinth (1:1), rice straw and water hyacinth (1:2), and rice straw and water hyacinth (2:1), in Pokhara, Kaski from April to June in 2022..

Energy & fatigueMetabolic healthRespiratory

Mesima · 2023 · Journal Article · Fitoterapia

Phellinus linteus mycelia extract in COVID-19 prevention and identification of its key metabolic compounds profiling using UPLC-QTOF-MS/MS spectrometry.

For centuries, food, herbal medicines, and natural products have been valuable resources for discovering novel antiviral drugs, uncovering new structure-activity relationships, and developing effective strategies to prevent/treat viral infections..

Energy & fatigueGut & microbiomeSkin & hydration

Lion's Mane · 2023 · Research Article · Frontiers in nutrition

Preparation, characterization, and property evaluation of Hericium erinaceus peptide-calcium chelate.

Recently, owing to the good calcium bioavailability, peptide-calcium chelates made of various foods have been emerging. Hericium erinaceus, an edible fungus, is rich in proteins with a high proportion of calcium-binding amino acids.

Enoki · 2023 · Journal Article · International journal of biological macromolecules

Pullulan-stabilized Soybean Phospholipids/Cinnamaldehyde emulsion for Flammulina velutipes preservation.

Fresh mushrooms (Flammulina velutipes) are very perishable and easily brown; also they undergo postharvest loss of nutritive constituents. In this study, cinnamaldehyde (CA) emulsion was prepared by using soybean phospholipids (SP) as emulsifier and pullulan (Pul) as stabilizer..

Chaga · 2023 · Research Article · International journal of molecular sciences

Renoprotective Impacts of Inonotus obliquus Ethanol-Ethyl Acetate Extract on Combined Streptozotocin and Unilateral Nephrectomy-Induced Diabetic Nephropathy in Mice.

Diabetes nephropathy (DN) is one of the most common causes of end stage renal disease (ESRD) globally. Medication options to stop or slow the progression of chronic renal disease (CKD) are limited, and patients with DN remain at a high risk of developing renal failure..

Immune supportEnergy & fatigueGut & microbiomeRespiratory

King Oyster · 2022 · Journal Article · Fish & shellfish immunology

A synbiotic containing prebiotic prepared from a by-product of king oyster mushroom, Pleurotus eryngii and probiotic, Lactobacillus plantarum incorporated in diet to improve the growth performance and health status of white shrimp, Litopenaeus vannamei.

This study aimed to evaluate the effects of a synbiotic composite an extract from a by-product of king oyster mushroom, Pleurotus eryngii (KOME), and probiotic Lactobacillus plantarum 7-40 on the growth performance and health status of white shrimp, Litopenaeus vannamei..

Energy & fatigueMetabolic healthSkin & hydration

Oyster Mushroom · 2022 · Journal Article · Food research international (Ottawa, Ont.)

Activation of mycelial defense mechanisms in the oyster mushroom Pleurotus ostreatus induced by Tyrophagus putrescentiae.

Lion's Mane · 2022 · Research Article · Journal of advanced pharmaceutical technology & research

Antibiofilm activity and bioactive phenolic compounds of ethanol extract from the Hericium erinaceus basidiome.

Biofilm formation has become a serious health and environmental problem. Mushrooms are now considered a valuable source of bioactive compounds with antimicrobial properties.