MycoData

It has been demonstrated that the Phellinus linteus (PL) mushroom, which mainly consists of polysaccharides, possesses antitumour activity. The mechanisms of PL against malignant growth remain unknown.

OncologyImmune support

Medium relevance

Niu-Chang-Chih · 2006 · Patent · journal metadata

Polysaccharide and composition from Antrodia camphorata and use thereof

The invention relates to polysaccharide extracted from Antrodia camphorata and the method for preparing the polysaccharide. The invention also relates to compositions and methods for hepatoprotective effect..

Immune supportLiver support

Medium relevance

Snow Fungus · 2006 · Research Support, Non U.S. Gov'T · Journal of biotechnology

Production of exopolysaccharides by submerged mycelial culture of a mushroom Tremella fuciformis.

The optimization of submerged culture conditions for mycelial growth and exopolysaccharide (EPS) production in an edible mushroom Tremella fuciformis was studied in shake flasks and bioreactors..

Immune supportMetabolic health

Medium relevance

Niu-Chang-Chih · 2006 · Research Support, Non U.S. Gov'T · International journal of food microbiology

Promotion of hyphal growth and underlying chemical changes in Antrodia camphorata by host factors from Cinnamomum camphora.

The aim of this research was to investigate the hyphal growth-promoting factors (HGFs) of Antrodia camphorata from the host-related species, Cinnamomum camphora (CC) and the underlying chemical produced..

Immune supportEnergy & fatigueMetabolic health

Medium relevance

Enoki · 2006 · Research Support, Non U.S. Gov'T · Phytochemistry

Structural characterization of a polysaccharide and a beta-glucan isolated from the edible mushroom Flammulina velutipes.

Two polysaccharides were isolated from the basidiomycete Flammulina velutipes, via successive hot extraction with water, 2% and 25% aq. KOH, and then submitted to freeze-drying.

Immune support

Medium relevance

Reishi · 2026 · Journal Article · Journal of ethnopharmacology

Effect and mechanism of Ganoderma leucocontextum extract on cadmium-toxic nephropathy.

ETHNOPHARMACOLOGICAL RELEVANCE: Cadmium (Cd) can first damage the kidney, leading to renal tubular dysfunction and irreversible renal damage. Ganoderma lucidum is a traditional Chinese herb that can enhances kidney qi and is extensively used in the management of renal diseases..

OncologyImmune support

Medium relevance

Reishi · 2026 · Journal Article · Journal of ethnopharmacology

Lucidenic acid A drives PI3K/AKT/BDNF signaling to improve memory impairment in mice and alleviate cellular nerve damage.

ETHNOPHARMACOLOGICAL RELEVANCE: Enhancing memory and alleviating amnesia are among the conditions that Ganoderma lucidum has historically been used to treat. However, there are relatively few studies on the potential therapeutic effects of active ingredients derived from Ganoderma lucidum in the treatment of memory….

OncologyImmune supportCognition & nervesEnergy & fatigue

Medium relevance

Lion's Mane · 2026 · Journal Article · Computational biology and chemistry

Modulation of ABCB1 by Erinacerin S: Binding dynamics and transmembrane helix remodeling.

Erinacerins are a group of bioactive heterocyclic organic compounds known as Isoindolin-1-one metabolites with the molecular formula C8H9N, derived from the mycelia or fruiting bodies of the mushroom Hericium erinaceus. They are known for their neuroprotective, anti-inflammatory, and anticancer properties..

OncologyImmune supportCognition & nervesGut & microbiome

Medium relevance

Reishi · 2025 · Journal Article · Food Chemistry: X

Metabolomics-based analysis of changes in functional constituents and activities of Tartary buckwheat by solid-state fermentation with three kinds of edible-medicinal fungi

Solid-state fermentation of Tartary buckwheat using Auricularia auricula, Ganoderma lucidum, and Hericium erinaceus enhanced its functional components, increasing levels of phenols, polysaccharides, proteins, and amino acids, alongside improved antioxidant activity..

Immune supportMetabolic health

Medium relevance

Reishi · 2025 · Research Article · Pharmaceuticals (Basel, Switzerland)

Safety Considerations for Natural Products with Adaptogenic and Immunomodulating Activities.

Background/Objectives: Natural products with claimed adaptogenic and/or immunomodulatory effects are widely used in traditional medicine systems across Eurasia. These include herbal remedies (e.g., Panax ginseng), fungi (e.g., Ganoderma lucidum), and animal-derived substances (e.g., propolis from Apis mellifera)..

Immune supportGut & microbiomeLiver supportSkin & hydration

Medium relevance

Shiitake · 2024 · Research Article · Foods (Basel, Switzerland)

Effect of Frying Temperatures and Times on the Quality and Flavors of Three Varieties of Lentinus edodes.

The effects of frying times (1, 2, 3, and 4 min) and temperatures (140, 160, 180, and 200 °C) were investigated on the nutritional components, color, texture, and volatile compounds of three Lentinula edodes varieties (808, 0912, and LM) from Guizhou, China..

Immune supportSkin & hydration

Medium relevance

Reishi · 2024 · Research Article · Bioresources and bioprocessing

Evaluation of cosmetic efficacy of lychee seed fermentation liquid.

BACKGROUND: Lychee seeds were fermented by three kinds of bacteria (Lactobacillus plantarum, Saccharomyces cerevillus and ganoderma lucidum mycelium), and two effective strains were selected by two indexes of activity content and antioxidant, so as to further verify whether lychee seeds have waste multiplication….

Immune supportEnergy & fatigueGut & microbiomeSkin & hydration

Medium relevance

Lion's Mane · 2024 · Research Article · Foods (Basel, Switzerland)

Mitigating Oxidative Stress and Promoting Cellular Longevity with Mushroom Extracts.

Oxidative stress can disrupt the body's ability to fight harmful free radicals, leading to premature aging and various health complications. This study investigated the antioxidant and anti-aging properties of four medicinal and edible mushrooms: Ganoderma lucidum, Hericium erinaceus, Pleurotus ostreatus, and Agaricus….

Immune supportEnergy & fatigueSkin & hydration

Medium relevance

Reishi · 2023 · Research Support, Non U.S. Gov'T · Scientific reports

Immuno-physiological effects of dietary reishi mushroom powder as a source of beta-glucan on Rohu, Labeo rohita challenged with Aeromonas veronii.

Beta-glucans have immense potential to stimulate immune modulation in fish by being injected intramuscularly, supplemented with feed or immersion routes of administration. We studied how supplementing Labeo rohita's diet with reishi mushroom powder containing beta-glucan influenced immunological function..

Immune supportEnergy & fatigueLiver supportRespiratory

Medium relevance

Maitake · 2022 · Brief Report · BMC research notes

CD3Ɛ immune restorative ability induced by Maitake Pro4x in immunosupressed BALBc mice.

OBJECTIVES: The aim of this research was to determine if the rich beta glucan compound called Maitake Pro4X can recover the T cell/NK population depleted by Dexamethasone treatment in lymph nodes from cancer-free BALBc female mice..

OncologyImmune support

Medium relevance

Nameko · 2022 · Research Support, Non U.S. Gov'T · Journal of food biochemistry

Chemical properties and anti-fatigue effect of polysaccharide from Pholiota nameko.

The aim of this study was to explore the primary chemical properties and anti-fatigue effect in vivo of Pholiota nameko polysaccharide (PNP). Through UV-visible spectrum, the absorption peaks of proteins, nucleic acids and pigments were not found..

Immune supportCognition & nervesEnergy & fatigue

Medium relevance

Shiitake · 2022 · Comparative Study · Journal of the science of food and agriculture

Role of thermal and non-thermal drying techniques on drying kinetics and the physicochemical properties of shiitake mushroom.

BACKGROUND: Fresh shiitake mushrooms are rich in nutrients, but have high water content, a fast metabolism after harvest, and deteriorate extremely easily. Therefore, the drying of shiitake mushrooms has become a research direction..

Immune support

Medium relevance

Nameko · 2022 · Research Support, Non U.S. Gov'T · Journal of food biochemistry

Structure characterization and antioxidant activity of carboxymethylated polysaccharide from Pholiota nameko.

The objective of this paper was to prepare the carboxymethyl polysaccharide of Pholiota nameko (CPPN) and further evaluate its structural characteristics, water solubility, and antioxidant activities..

Immune support

Medium relevance

Shiitake · 2021 · Other · Nutrients

Combining the Anticancer and Immunomodulatory Effects of Astragalus and Shiitake as an Integrated Therapeutic Approach.

Astragalus root (Huang Qi) and Shiitake mushrooms (Lentinus edodes) are both considered medicinal foods and are frequently used in traditional Chinese medicine due to their anticancer and immunomodulating properties..

OncologyImmune support

Medium relevance

Shiitake · 2021 · Evaluation Study · Journal of the science of food and agriculture

Intensive pulsed light pretreatment combined with controlled temperature and humidity for convection drying to reduce browning and improve quality of dried shiitake mushrooms.

BACKGROUND: The change of surface color caused by browning during the drying process of shiitake mushrooms seriously affects its market circulation. Intensive pulsed light (IPL) as a non-heat-treatment method can reduce enzyme activity by changing the enzyme structure..

Immune supportEnergy & fatigue

Medium relevance

Wood Ear · 2017 · Journal Article · Roczniki Panstwowego Zakladu Higieny

Quantitative evaluation of 1,3,1,6 β-D-glucan contents in wild-growing species of edible Polish mushrooms.

BACKGROUND: Macrofungal β-glucans are mainly represented by compounds with β-1,3- and β-1,6 glycosidic bonds. They have been shown to have immunomodulatory, anticancer, and antioxidant properties..

OncologyImmune support

Medium relevance

Turkey Tail · 2010 · Patent · journal metadata

Strain Of Turkey Tail Mushroom, Extract From The Same, And Use Of The Same

The present invention provides a new strain of turkey tail mushroom (Trametes versicolor (L.: Fr.) Pilat) having excellent biological activities (Accession number: FERM BP-10633)..

OncologyImmune supportMetabolic healthSkin & hydration

Medium relevance

Chaga · 2009 · Patent · journal metadata

MANUFACTURING METHOD NANO PARTICLE CHAGA MUSHROOM

A composition for hair dyeing with nano particle of Inonotus Obliquus is provided to ensure hair dyeing effect by bonding with the keratin of hair dyeing, remove the smell by oxidization and strengthen hair root by beta glucan..

Immune support

Medium relevance

Turkey Tail · 2008 · Patent · journal metadata

STRAIN OF TURKEY TAIL MUSHROOM, EXTRACT FROM THE SAME, AND USE OF THE SAME

The present invention provides a new strain of turkey tail mushroom (Trametes versicolor (L.:Fr.)Pilat) having excellent biological activities (Accession number: FERM BP-10633)..

OncologyImmune supportMetabolic healthSkin & hydration

Medium relevance

Lion's Mane · 2026 · Systematic Review · Medical sciences (Basel, Switzerland)

Application of Medicinal Mushrooms for the Treatment of Peripheral Nerve Injury: A Systematic Review.

Background/Objective: Current treatments for peripheral nerve injury (PNI) lack robust evidence to suggest complete recovery; hence, alternative therapeutics offer new opportunities to develop more effective protocols..

Immune supportCognition & nerves

Medium relevance

Cordyceps · 2026 · Review · Die Naturwissenschaften

Research advances on Cordyceps sinensis and its components in relation to omics biomarkers for the neurological disorders.

Cordyceps is a traditional medicinal fungus belonging to the species Ophiocordyceps sinensis. It grows in the alpine ecological zone of the Tibetan Plateau and exhibits dual characteristics of both insects and fungi.

OncologyImmune supportCognition & nervesEnergy & fatigue

Medium relevance

Oyster Mushroom · 2025 · Review · Heliyon

A comprehensive review on multifunctional bioactive properties of elm oyster mushroom Hypsizygus ulmarius (Bull.) Redhead (Agaricomycetes): Current research, challenges and future trends.

Mushrooms have evolved as a nutritional powerhouse, harnessing a diverse spectrum of bioactive molecules to fortify human health. Hypsizygus ulmarius represents a pioneering species within the oyster mushrooms distinguished by its unique characteristics and potential abilities..

OncologyImmune support

Medium relevance

Cordyceps · 2025 · Systematic Review · Frontiers in pharmacology

Efficacy of Xiaoyao-san preparations in treating Hashimoto's thyroiditis: a meta-analysis and systematic review.

OBJECTIVE: To assess Xiaoyao-san (XYS) preparations' effectiveness in treating Hashimoto's thyroiditis. METHODS: Eight databases were searched for randomized controlled trials (RCTs) comparing XYS preparations to a low-iodine diet (LID), selenium yeast (SY), levothyroxine (LT4), or Ophiocordyceps sinensis (OS) for HT….

Immune support

Medium relevance

Reishi · 2025 · Systematic Review · Carbohydrate research

Structural basis of immunomodulation by edible fungal polysaccharides: From molecular characteristics to action mechanisms.

Edible Fungal polysaccharides as Immunomodulators: A Systematic Review at the Crossroads of Immunology, Natural Products Chemistry, and Microbiology. The chemical structure-specifically molecular weight, branching degree, and functional group modifications-directly dictates immunological activity..

OncologyImmune supportCognition & nervesMetabolic health

Medium relevance

Cordyceps · 2024 · Review · Frontiers in pharmacology

Use of bailing capsules (cordyceps sinensis) in the treatment of chronic kidney disease: a meta-analysis and network pharmacology.

The Bailing Capsule is a commonly used traditional Chinese medicine for the treatment of chronic kidney disease (CKD). However, its therapeutic effects and pharmacological mechanisms have not been fully explored..

OncologyImmune support

Medium relevance

King Oyster · 2022 · Journal Article · International journal of biological macromolecules

A fungal cellulose nanocrystals-based approach to improve the stability of triterpenes loaded Pickering emulsion.

Depolysaccharide residues of edible fungus Pleurotus eryngii (dePSR-Pe), a mushroom industry waste, have abundant cellulose. In this study, the cellulose nanocrystals of P.

OncologyImmune supportGut & microbiome

Medium relevance

King Oyster · 2022 · Research Article · Microorganisms

Biochemical Evaluation of Agaricus and Pleurotus Strains in Batch Cultures for Production Optimization of Valuable Metabolites.

The production of various biochemical compounds such as proteins, glucans and glucanases, from the mycelium of four strains of Basidiomycetes species, Agaricus bisporus, Agaricus subrufescens, Pleurotus eryngii and Pleurotus ostreatus, during batch culture in shaking flasks, was studied..

Immune supportMetabolic health

Medium relevance

Chaga · 2022 · Research Article · Molecules (Basel, Switzerland)

Evaluation of Toxicity and Efficacy of Inotodiol as an Anti-Inflammatory Agent Using Animal Model.

Chaga mushroom (Inonotus obliquus) comprises polyphenolic compounds, triterpenoids, polysaccharides, and sterols. Among the triterpenoid components, inotodiol has been broadly examined because of its various biological activities..

Immune support

Medium relevance

King Oyster · 2022 · Journal Article · International journal of medicinal mushrooms

Suppressive Effect of Fruiting Bodies of Medicinal Mushrooms on Demyelination and Motor Dysfunction in a Cuprizone-Induced Multiple Sclerosis Mouse Model.

Epidemiologic studies have shown a high prevalence of multiple sclerosis (MS) in Europe and North America, and a low prevalence in East Asia. Mushrooms contain various biological response modifiers (BRMs) and are widely used in traditional Chinese medicine in East Asian countries..

Immune supportCognition & nervesMetabolic health

Medium relevance

Cordyceps · 2021 · Research Article · Molecules (Basel, Switzerland)

Cordycepin Sensitizes Cholangiocarcinoma Cells to Be Killed by Natural Killer-92 (NK-92) Cells.

Immunotherapy harnessing immune functions is a promising strategy for cancer treatment. Tumor sensitization is one approach to enhance tumor cell susceptibility to immune cell cytotoxicity that can be used in combination with immunotherapy to achieve therapeutic efficiency..

OncologyImmune support

Medium relevance

Cordyceps · 2021 · Journal Article · International journal of biological macromolecules

Structure and immunomodulatory activity of a water-soluble α-glucan from Hirsutella sinensis mycelia.

Hirsutella sinensis, the anamorph of Ophiocordyceps sinensis (syn. Cordyceps sinensis), is a great substitute for precious and rare wild Cordyceps sinensis to effectively treat a variety of lung and kidney diseases..

Immune supportRespiratory

Medium relevance

Lion's Mane · 2020 · Journal Article · International journal of biological macromolecules

A novel Hericium erinaceus polysaccharide: Structural characterization and prevention of H2O2-induced oxidative damage in GES-1 cells.

In this paper, the structural characteristics and bioactivity of a novel polysaccharide from H. erinaceus (HEPN) were investigated, wherein, physico-chemical characterization demonstrated that HEPN with an average molecular weight of 12.713 kDa was composed of mannose (5.13%), glucose (43.02%), and galactose (51.85%)..

Immune supportEnergy & fatigueMetabolic health

Medium relevance

Reishi · 2020 · Journal Article · Biological and Pharmaceutical Bulletin

Amelioration of the Lipogenesis, Oxidative Stress and Apoptosis of Hepatocytes by a Novel Proteoglycan from Ganoderma lucidum

The steatosis and resultant oxidative stress and apoptosis play the important roles in the progression of nonalcoholic fatty liver disease (NAFLD), therefore, searching for the effective drugs against NAFLD has been a hot topic..

OncologyImmune supportEnergy & fatigueMetabolic health

Medium relevance

Enoki · 2020 · Research Article · Animals: an open access journal from MDPI

Dietary Supplementation with Flammulina velutipes Stem Waste on Growth Performance, Fecal Short Chain Fatty Acids and Serum Profile in Weaned Piglets.

This study was conducted to evaluate the effects of dietary FVS supplementation on growth performance, nutrient digestibility, biochemical profile of serum and fecal short chain fatty acids (SCFAs) production in weaned piglets..

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

Medium relevance

Shiitake · 2020 · Journal Article · Japanese Journal of Complementary and Alternative Medicine

Evaluation of the Effect of Lentinula Edodes Mycelia Extract on Immune Function in Healthy Subjects Placebo-controlled, Parallel-group Study

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in Japanese Journal of Complementary and Alternative Medicine in 2020. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Immune support

Medium relevance

Maitake · 2020 · Journal Article · Food Science and Technology Research

Fabrication and Characterization of Grifola frondosa Protein Hydrolysate-selenium Chelate

Metadata-grounded summary: This journal article indexes research on Grifola frondosa in Food Science and Technology Research in 2020. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Immune support

Medium relevance

Turkey Tail · 2020 · Journal Article · Food Science and Technology Research

Fermentation Production, Purification and Characterization of a Fungal α-galactosidase from Trametes versicolor and Its Synergistic Degradation of Guar Gum with Mannanase

Metadata-grounded summary: This journal article indexes research on Trametes versicolor in Food Science and Technology Research in 2020. MycoData maps the paper to oncology, immune support based on its title, species context, article metadata, and study classification..

OncologyImmune support

Medium relevance

Shiitake · 2020 · Journal Article · Mushroom Science and Biotechnology

Lentinula edodes methanol extract inhibits biofilm formation and autoinducer-2 production by Eikenella corrodens, a periodontopathogenic bacterium

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in Mushroom Science and Biotechnology in 2020. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

Immune supportGut & microbiome

Medium relevance

Shiitake · 2020 · Journal Article · Minerva gastroenterologica e dietologica

Possible therapeutic role of a highly standardized mixture of active compounds derived from cultured Lentinula edodes mycelia (AHCC) in patients infected with 2019 novel coronavirus.

The outbreak of SARS-CoV-2 disease (COVID-19) is currently, March 2020, affecting more than 100,000 people worldwide and, according to the WHO (World Health Organization), a pandemic is shortly expected..

Immune supportLiver supportRespiratory

Medium relevance

Lion's Mane · 2020 · Journal Article · International journal of biological macromolecules

Preparation, characterization and controlled-release property of CS crosslinked MWCNT based on Hericium erinaceus polysaccharides.

In present study, the optimal condition of prepared drug was determined by response surface methodology. In addition, their physicochemical properties, drug release and uptake ability of CS-MWCNT-HEP were studied, and the distribution of the drug in ICR mice and the sites of action were further evaluated..

Immune supportLiver support

Medium relevance

Shiitake · 2020 · Journal Article · Mushroom Science and Biotechnology

Purification and characterization of endo-polygalacturonase from white-rot fungus Lentinula edodes

Immune supportGut & microbiome

Medium relevance

Almond Mushroom · 2020 · Research Article · Central-European journal of immunology

The significance of Agaricus blazei as an immunomodulator of the level of IL-17 in Balb/C mice with atherosclerosis.

Atherosclerosis is a disease caused by an inflammatory response which involved the interaction between endothelial cells, macrophages and lymphocytes, and is closely related to IL-17 regulation..

Immune support

Medium relevance

Maitake · 2020 · Journal Article · International journal of biological macromolecules

The structural characteristics of an acid-soluble polysaccharide from Grifola frondosa and its antitumor effects on H22-bearing mice.

The edible mushroom G. frondosa has been used as a kind of functional food for the prevention and therapy of various diseases in Asian countries.

OncologyImmune support

Medium relevance

Enoki · 2020 · Journal Article · Abstracts of Papers Presented at the Meeting of the Mycological Society of Japan

Variation of deviations from equal segregation of conjugate nuclei in oidia among dikaryotic stocks of Flammulina velutipes

Metadata-grounded summary: This journal article indexes research on Flammulina velutipes in Abstracts of Papers Presented at the Meeting of the Mycological Society of Japan in 2020. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Immune support

Medium relevance

Maitake · 2019 · Journal Article · International journal of biological macromolecules

Effect of Grifola frondosa polysaccharide on anti-tumor activity in combination with 5-Fu in Heps-bearing mice.

GP11 had been reported to have effectively anti-tumor activity by improving the immune function in our previous study. To avoid drawbacks of the 5-Fu, GP11 in combination with 5-Fu was investigated in this study.

OncologyImmune support