MycoData

Oyster Mushroom · 2020 · Journal Article · Journal of oleo science

Effects of Sphingolipid Fractions from Golden Oyster Mushroom (Pleurotus citrinopileatus) on Apoptosis Induced by Inflammatory Stress in an Intestinal Tract in vitro Model

Previously, we reported that the polar lipid fraction from the golden oyster mushroom, Pleurotus citrinopileatus, suppresses colon injuries which result from apoptosis induced by inflammatory stresses in vivo and in vitro (Yamashita et al., J. Oleo Sci., 69, 751-757 (2020))..

Immune supportSkin & hydration

Shiitake · 2020 · Journal Article · Food chemistry

Effects of UV-C treatment and ultrafine-grinding on the biotransformation of ergosterol to vitamin D2, physiochemical properties, and antioxidant properties of shiitake and Jew's ear.

In the present study, the impact of ultraviolet (UV)-C treatment and ultrafine grinding on the conversion of ergosterol to vitamin D2, physiochemical properties, and antioxidant properties of shiitake and Jew's ear was assessed..

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

Oyster Mushroom · 2020 · Journal Article · Frontiers in veterinary science

Influence of Oyster Mushroom Waste on Growth Performance, Immunity and Intestinal Morphology Compared With Antibiotics in Broiler Chickens.

Oyster mushroom waste (OMW) is a by-product of the agriculture industry with valuable antimicrobial, antioxidant, antifungal, and prebiotic properties. This by-product might be a useful alternative to antibiotic growth stimulators in poultry nutrition..

Immune supportLiver support

Shiitake · 2020 · Journal Article · Nutrients

Protective Role of Shiitake Mushroom-Derived Exosome-Like Nanoparticles in D-Galactosamine and Lipopolysaccharide-Induced Acute Liver Injury in Mice.

Fulminant hepatic failure (FHF) is a rare, life-threatening liver disease with a poor prognosis. Administration of D-galactosamine (GalN) and lipopolysaccharide (LPS) triggers acute liver injury in mice, simulating many clinical features of FHF in humans; therefore, this disease model is often used to investigate….

Immune supportRespiratory

Shiitake · 2020 · Journal Article · Letters in applied microbiology

Purified β-glucans from the Shiitake mushroom ameliorates antibiotic-resistant Klebsiella pneumoniae-induced pulmonary sepsis.

Bacterial infection remains the main cause of acute respiratory distress syndrome and is a leading cause of death and disability in critically ill patients. Here we report on the use of purified β-glucan (lentinan) extracts from Lentinus edodes (Shiitake) mushroom that can reduce infection by a multidrug-resistant….

Immune supportEnergy & fatigue

Shiitake · 2019 · Journal Article · International journal of medicinal mushrooms

Comprehensive Evaluation of Shiitake Strains (Lentinus edodes, Agaricomycetes) Based on Polysaccharide Content and Agronomic Traits.

Polysaccharides are some of the most important bioactive compounds in Lentinus edodes, but little attention has been devoted to the genetic basis of polysaccharide content..

Nameko · 2019 · Journal Article · International journal of biological macromolecules

Effect of ultrasound-assisted extraction on physicochemical properties and TLR2-affinity binding of the polysaccharides from Pholiota nameko.

The effect of the ultrasonic treatment on the physicochemical properties, oil-holding capacities, foaming capacities, and TLR2-affinity of the polysaccharides from Pholiota nameko (PNPS), was evaluated..

Shiitake · 2019 · Journal Article · International journal of biological macromolecules

Preparation and properties of water-in-oil shiitake mushroom polysaccharide nanoemulsion.

Shiitake mushroom (Lentinus edodes) polysaccharide (SMP), an important immunomodulatory substance, is usually hard to be absorbed by the intestinal tract, because of its macromolecule characteristics..

Nameko · 2019 · Journal Article · Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire

Protective effect of polysaccharides from Pholiota nameko on Lactobacillus casei ATCC 334 subjected to freeze-drying

This paper evaluated the benefit of the polysaccharides from Pholiota Nameko (PNPS-1) as a cryoprotectant for maintaining the viability of Lactobacillus casei ATCC 334 during freeze-drying and subsequent storage. The data showed that all the freeze-dried L..

Immune supportMetabolic health

Nameko · 2019 · Journal Article · Natural product research

Structural properties and antioxidant activities of polysaccharide from fruit bodies of Pholiota nameko.

A polysaccharide named PNP was extracted and purified from Pholiota nameko. The total sugar content of PNP was 95.29% and the molecular weight was 1.89 × 103 kDa..

OncologyImmune supportEnergy & fatigueMetabolic health

Shiitake · 2018 · Journal Article · ACS applied materials & interfaces

Conformation-Dependent Manipulation of Human Islet Amyloid Polypeptide Fibrillation by Shiitake-Derived Lentinan.

Misfolding and aggregation of human islet amyloid polypeptide (hIAPP) into fibrils are important contributions to the pathology of type 2 diabetes. Developing effective inhibitors of protein aggregation and fibrillation has been considered a promising therapeutic approach to preventing and treating type 2 diabetes..

Immune supportMetabolic healthGut & microbiome

Nameko · 2017 · Journal Article · Food chemistry

Chemical and structural characterization of Pholiota nameko extracts with biological properties.

Edible mushrooms including Pholiota nameko are excellent sources of extractable bioactive compounds with much to explore. Enzymatic extractions with Cellulase and Viscozyme were responsible for highest extraction yields (67-77%)..

OncologyImmune supportEnergy & fatigue

Shiitake · 2017 · Journal Article · International journal of medicinal mushrooms

Selective Cytotoxic Activity of Se-Methyl-Seleno-L-Cysteine- and Se-Polysaccharide-Containing Extracts from Shiitake Medicinal Mushroom, Lentinus edodes (Agaricomycetes).

Numerous formulations derived from the shiitake medicinal mushroom, Lentinus edodes, demonstrate anticancer activities. We hypothesized that isolates from selenium (Se)-enriched mycelia of L.

Nameko · 2016 · Journal Article · International journal of medicinal mushrooms

A Polysaccharide from the Culinary-Medicinal Mushroom Pholiota nameko (Agaricomycetes) Inhibits the NF-κB Pathway in Dendritic Cells Through the TLR2 Receptor.

A polysaccharide purified from Pholiota nameko (PNPS-1) was found to have anticancer and anti-inflammatory activity. This study investigated the effect of PNPS-1 on the nuclear factor (NF)-κB signaling pathway of TLR2 small interfering RNA-silenced murine bone marrow-derived dendritic cells (BMDCs) and relevant….

OncologyImmune support

OncologyImmune supportGut & microbiomeRespiratory

Shiitake · 2016 · Journal Article · Journal of agricultural and food chemistry

Elm Tree (Ulmus parvifolia) Bark Bioprocessed with Mycelia of Shiitake (Lentinus edodes) Mushrooms in Liquid Culture: Composition and Mechanism of Protection against Allergic Asthma in Mice.

Mushrooms can break down complex plant materials into smaller, more digestible and bioactive compounds. The present study investigated the antiasthma effect of an Ulmus parvifolia bark extract bioprocessed in Lentinus edodes liquid mycelium culture (BPUBE) against allergic asthma in chicken egg ovalbumin….

Maitake · 2003 · Research Article · Zhongguo sheng wu gong cheng za zhi = Journal of Chinese biotechnology

Extraction, Sulfation and Immunological Test of Maitake D-fraction

The key tests in the evaluation of orbital pathology--orbital roentgenograms, CT scans, and ultrasonography--are defined..

OncologyImmune supportMetabolic health

Maitake · 2002 · Journal Article · Research communications in molecular pathology and pharmacology

Effects of Maitake mushroom fractions on blood pressure of Zucker fatty rats.

A link exists between insulin resistance and many chronic disorders of aging including advancing-age. A safer means to prevent or, at least, slow the erosion of insulin sensitivity would provide a novel approach to better health..

Maitake · 2000 · Journal Article · Molecular urology

Induction of apoptosis in human prostatic cancer cells with beta-glucan (Maitake mushroom polysaccharide).

PURPOSE: To explore more effective treatment for hormone-refractory prostate cancer, we investigated the potential antitumor effect of beta-glucan, a polysaccharide of the Maitake mushroom, on prostatic cancer cells in vitro..

OncologyImmune support

Shiitake · 2026 · Published Erratum · Journal of the science of food and agriculture

Correction to 'Role of thermal and non-thermal drying techniques on drying kinetics and the physicochemical properties of shiitake mushroom'.

Metadata-grounded summary: This published erratum indexes research on Lentinula edodes in Journal of the science of food and agriculture in 2026. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

Shiitake · 2026 · Published Erratum · Journal of the science of food and agriculture

Correction to "Intensive pulsed light pretreatment combined with controlled temperature and humidity for convection drying to reduce browning and improve quality of dried shiitake mushrooms".

Immune supportMetabolic healthGut & microbiome

Cordyceps · 2026 · Published Erratum · Metabolites

Correction: Sun et al. Effects of Cordyceps cicadae Polysaccharide on Gut Microbiota, the Intestinal Mucosal Barrier, and Inflammation in Diabetic Mice. Metabolites 2025, 15, 8.

The authors would like to make the following correction to their published paper [...]..

Immune supportSkin & hydrationRespiratory

Reishi · 2026 · Preprint · journal metadata

Ganoderic acid L alleviates lung injury through PI3K/MAPKs signaling revealed by network pharmacology, molecular dynamics and transcriptomics

Abstract Background/Objectives: Ganoderma lucidum is widely used for inflammatory disorders, but its key active compounds and direct targets in acute lung injury (ALI) remain unclear. This study aimed to identify the major active triterpenoid from G..

Immune supportEnergy & fatigueGut & microbiome

Oyster Mushroom · 2026 · Preprint · journal metadata

Impact of Enzymatic Pretreatment on the Anaerobic Digestion of Coffee Processing Wastewater

Abstract Coffee processing generates large amounts of wastewater, especially during the pulping and fermentation stages. This wastewater has high chemical oxygen demand (COD) and biochemical oxygen demand (BOD) and contains macromolecules such as polyphenols, tannins, polysaccharides, and caffeine, which are….

Immune supportCognition & nervesEnergy & fatigue

Lion's Mane · 2026 · Review · International journal of molecular sciences

Natural Molecules for Brain Health and Resilience.

The global rise in cognitive decline and neurodegenerative disorders has intensified the search for safe and accessible strategies to support brain health. In recent years, nutraceuticals have gained considerable attention as potential modulators of neurological function due to their antioxidant, anti-inflammatory,….

Turkey Tail · 2026 · Letter · ANZ journal of surgery

Non-Steroidal Anti-Inflammatory Drugs, Turkey Tail Mushrooms and Hidden Platelet Dysfunction: Lessons From a Post-Oesophagectomy Haemorrhage.

Metadata-grounded summary: This letter indexes research on Trametes versicolor in ANZ journal of surgery in 2026. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

OncologyImmune supportEnergy & fatigue

Cordyceps · 2026 · Review · The American journal of Chinese medicine

Research Progress on the Molecular Mechanisms of Cordycepin in Modulating Inflammation.

Cordycepin is a bioactive compound isolated from the Cordyceps fungi. It is structurally analogous to adenosine and possesses potent anti-inflammatory and immunomodulatory properties..

Shiitake · 2026 · Case Reports · Oxford medical case reports

Shiitake mushroom-induced flagellate erythema.

Metadata-grounded summary: This case reports indexes research on Lentinula edodes in Oxford medical case reports in 2026. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

Immune supportMetabolic healthGut & microbiomeLiver support

Cordyceps · 2025 · Review · Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

[Research progress on dihydrochalcones from Lithocarpus litseifolius extracts in treatment of type 2 diabetes mellitus and its complications].

Type 2 diabetes mellitus(T2DM) is a prevalent metabolic and endocrine disorder. Long-term hyperglycemia can lead to severe chronic complications, imposing substantial economic burdens on both society and patients..

Reishi · 2025 · Preprint · journal metadata

A zebrafish immunodeficiency model induced by the combination of Tacrolimus and Everolimus for rapid assessment of immune-enhancing agents

A methodology for the assessment of the immune-enhancing effects of various substances within a period of 5 days was reported. Experimentally, it was determined that the continuous treatment of Tacrollimus (0.5 ng/mL) and Everolimus (5 μg/mL) on zebrafish from 48 hpf to 120 hpf was sufficient to establish an….

OncologyImmune supportCognition & nervesLiver support

Niu-Chang-Chih · 2025 · Review · Journal of the Chinese Medical Association: JCMA

Anti-inflammatory and anticancer effects of polysaccharides from Antrodia cinnamomea: A review.

Antrodia cinnamomea ( Ac ), also known as "Niu-Chang-Chih" in Chinese, is a valuable fungus that has been widely used as medicine and food among indigenous people in Taiwan. Ac is rich in polysaccharides ( Ac -PS), making it a promising candidate for adjunctive therapy in cancer and inflammation conditions..

Cordyceps · 2025 · Review · The American journal of Chinese medicine

Anti-Inflammatory Effects of Bioactive Peptides from Chinese Herbal Medicine: A Review.

Inflammation is a pathological process implicated in a wide range of diseases, and is orchestrated by complex regulatory networks at both transcriptional and post-transcriptional levels..

Cordyceps · 2025 · Review · Phytomedicine: international journal of phytotherapy and phytopharmacology

Bibliometric analysis of literature on natural medicines against chronic kidney disease from 2001 to 2024.

BACKGROUND: Chronic kidney disease (CKD) is a globally common and progressive disease. There has been few bibliometric study to analyze the status, hot spots, and trends in the field of natural medicines (NMs) against CKD..

Cordyceps · 2025 · Review · Iranian journal of pharmaceutical research: IJPR

Chinese Herbal Medicine in the Treatment of Chronic Kidney Disease: A Narrative Review of Mechanisms and Therapeutic Potential.

CONTEXT: Chronic kidney disease (CKD) is a significant global health issue, characterized by its progressive nature and the limited effectiveness of conventional treatments. Chinese herbal medicine (CHM) has been used for centuries in East Asia to manage CKD by targeting key pathological processes..

Zhu Ling · 2025 · Preprint · journal metadata

Fluorescence and Phosphorescence Assay of -D Glucans from Basidiomycete Medicinal Mushrooms

Basidiomycete mushrooms contain complex -D-glucans which play an important role in immuno-modulating and anti-tumor activities. The present work involves a novel and intrinsic synchronous fluorescent and phosphorescence assay method for -D-glucans..

OncologyImmune support

Shiitake · 2025 · Review · International journal of molecular sciences

Food-Derived Phytochemicals: Multicultural Approaches to Oxidative Stress and Immune Response.

This review will focus on how ethnic consumption of foods such as shiitake, ginseng, turmeric, black seeds, berries, rosemary, moringa and holy basil can help act as antioxidants and immune modulators in fighting many diseases..

OncologyImmune supportMetabolic health

Reishi · 2025 · Preprint · journal metadata

Genome-Wide CRISPR/Cas9 Screening Reveals Lipid Metabolism and Inflammatory Signalling as Modulators of Ganoderic Acid DM Cytotoxicity

Ganoderic Acid DM (GA-DM), a triterpenoid derived from Ganoderma lucidum, exhibits anti-cancer and anti-diabetic activities, but the underlying mechanisms of action remain unclear. To identify genetic modulators of GA-DM response, we conducted a genome-wide CRISPR/Cas9 knockout screen in human melanoma cells..

Immune supportSkin & hydration

Reishi · 2025 · Scoping Review · Lupus science & medicine

Identifying immunostimulatory herbal supplements that may flare autoimmune skin diseases: a systematic scoping review.

OBJECTIVE: To systematically identify herbal supplements with immunostimulatory properties that may trigger or exacerbate autoimmune skin diseases. METHODS: We conducted a systematic scoping review in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews….

Immune supportMetabolic healthGut & microbiome

Oyster Mushroom · 2025 · Review · Frontiers in microbiology

Microbiome engineering to enhance disease resistance in aquaculture: current strategies and future directions.

Aquaculture, a cornerstone of global food security, faces critical threats from disease outbreaks, antimicrobial resistance, and ecological disruption. Through a narrative analysis of over 160 studies, this review synthesizes advances in microbiome engineering-a sustainable approach to enhancing disease resistance in….

OncologyImmune supportEnergy & fatigue

Cordyceps · 2025 · Review · Food science & nutrition

Mushroom Bioactive Molecules as Anticancerous Agents: An Overview.

Mushrooms have long been used in Traditional Chinese medicine (TCM), where they play an important role in promoting overall health and well-being. However, the therapeutic benefits of mushrooms have made this group of macrofungi a significant part of traditional medicine, particularly in Southeast Asia and China..

OncologyImmune supportCognition & nervesMetabolic health

Chaga · 2025 · Preprint · journal metadata

Mushroom-Derived Compounds as Inhibitors of Advanced Glycation End-Products

Mushrooms have long been valued not only as food but also for their medicinal properties, especially in Eastern European traditional medicine. Species such as Inonotus obliquus, Fomitopsis officinalis, Piptoporus betulinus and Fomes fomentarius have been used to treat gastrointestinal problems, cancers, respiratory….

OncologyImmune supportLiver support

Reishi · 2025 · Preprint · journal metadata

Potential for Medicinal Mushroom Extracts as an Adjunctive Treatment to Enhance Conversion Therapy in Colorectal Cancer with Liver and Peritoneal Involvement

Colorectal cancer (CRC) with liver metastases (LM) and peritoneal metastases (PM) presents a formidable challenge, with poor prognosis despite advances in systemic chemotherapy and combined surgical approaches like cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC)..

OncologyImmune supportLiver support

Reishi · 2025 · Preprint · journal metadata

Potential for Medicinal Mushroom Extracts as an Adjunctive Treatment to Enhance Conversion Therapy in Colorectal Cancer with Liver and Peritoneal Involvement

Immune supportSkin & hydration

Shiitake · 2025 · Letter · European annals of allergy and clinical immunology

Shiitake flagellate dermatitis: a case series from Italy.

Metadata-grounded summary: This letter indexes research on Lentinula edodes in European annals of allergy and clinical immunology in 2025. MycoData maps the paper to immune support, skin & hydration based on its title, species context, article metadata, and study classification..

Oyster Mushroom · 2025 · Review · Foods (Basel, Switzerland)

The Emerging Role of Oyster Mushrooms as a Functional Food for Complementary Cancer Therapy.

The importance of functional food's role in human nutrition as well as in the prevention of diseases, especially the treatment of chronic diseases like cancer, is an innovative field of research..

OncologyImmune supportEnergy & fatigueGut & microbiome

Oyster Mushroom · 2024 · Preprint · journal metadata

Computational Development of mushroom-6-Glucan/Paclitaxel as a Synergistic Complementary Medicine for Breast Cancer Therapy

Abstract Background Breast cancer is chemo-resistant and highly metastatic, often resulting in patient mortality. One of the primary factors contributing to the metastasis and chemotherapy resistance is the presence of cancer stem-like cells..

Shiitake · 2024 · Published Erratum · International journal of biological macromolecules

Corrigendum to "Incorporation of carbon dots into polyvinyl alcohol/corn starch based film and its application on shiitake mushroom preservation" [Int. J. Biol. Macromol. 280 (2024) 135998].

Metadata-grounded summary: This published erratum indexes research on Lentinula edodes in International journal of biological macromolecules in 2024. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

Immune supportCognition & nervesEnergy & fatigue

Reishi · 2024 · Preprint · journal metadata

Exopolysaccharides extracted from submerged cultures of Ganoderma lucidumactivate the NLRP3 inflammasome

Abstract Interleucin-1β (IL-1β) is a pivotal cytokine in pro-inflammatory response induction, and it is regarded as protective in various diseases. IL-1β secretion is mainly associated with activation of the inflammasome complex, which generally is tightly regulated, depending on two signals for significant activity..

Immune supportCognition & nervesRespiratory

Cordyceps · 2024 · Review · Frontiers in pharmacology

Geo-authentic Tibetan medicine: a traditional pharmacological resource for promoting human health and wellness.

Traditional Tibetan medicine (TTM) is an ancient healing system that has been practiced for more than 2,000 years and involves the use of various medicinal plants for preventing and treating acute mountain sickness, depression, asthma, etc..