MycoData

Metadata-grounded summary: This journal article indexes research on Cordyceps militaris in Probiotics and antimicrobial proteins in 2026. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

Immune supportGut & microbiome

High relevance

Cordyceps · 2025 · Journal Article · Journal of agricultural and food chemistry

CRISPR-Cas9/Safe Harbor-Targeted Overexpression of Glucan Synthase Gene CmGls in Edible Mushroom Cordyceps militaris.

The membrane-integrated β-1,3-glucan synthase is the key enzyme involved in the biosynthesis of the core component β-1,3-glucan of the fungal cell wall. To date, the precise and targeted insertion of the β-1,3-glucan synthase gene into the genomes of edible fungi for safe and predictable overexpression has been….

Immune supportEnergy & fatigue

High relevance

Cordyceps · 2025 · Journal Article · Plant science

Overexpression of Cordyceps militaris Cmcns1/cns2 gene to produce cordycepin results in increased resistance to Ralstonia solawacearum, Alternaria alternate and TMV in tobacco(Nicotiana tabacum L.)

Cordycepin (COR), the first nucleoside antibiotic isolated from fungi, exhibits antibacterial, antitumor, antiviral, and anti-inflammatory activities. In this study, we constructed a Cmcns1/cns2 fusion gene vector and transformed tobacco using Agrobacterium tumefaciens-mediated genetic transformation..

OncologyImmune supportRespiratory

High relevance

Cordyceps · 2025 · Journal Article · Plant science: an international journal of experimental plant biology

Overexpression of Cordyceps militaris Cmcns1/cns2 gene to produce cordycepin results in increased resistance to Ralstonia solawacearum, Alternaria alternate and TMV in tobacco(Nicotiana tabacum L.).

OncologyImmune supportRespiratory

High relevance

Nameko · 2025 · Journal Article · Journal of the Japanese Forest Society

Reutilization of Waste Nameko (Pholiota microspora) Mushroom Substrate for Cedar (Cryptomeria japonica) Sawdust Enokitake (Flammulina velutipes) Cultivation

Metadata-grounded summary: This journal article indexes research on Pholiota microspora in Journal of the Japanese Forest Society in 2025. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Immune support

High relevance

Nameko · 2025 · Journal Article · Journal of the Japanese Forest Society

Reutilization of Waste Nameko (Pholiota microspora) Mushroom Substrate for Oak (Quercus serrata) Sawdust Nameko Cultivation

Immune support

High relevance

Reishi · 2025 · Journal Article · JPMA. The Journal of the Pakistan Medical Association

Therapeutic potential of Ganoderma lucidum/ Reishi mushroom.

Metadata-grounded summary: This journal article indexes research on Ganoderma lucidum in JPMA. The Journal of the Pakistan Medical Association in 2025.

OncologyImmune supportMetabolic healthLiver support

High relevance

Shiitake · 2024 · Journal Article · Journal of the Japanese Forest Society

Effects of Inter- and Intra-tree Variations in 137Cs and K Concentrations of Konara Oak (Quercus serrata) on the 137Cs Transfer to Log-grown Shiitake Mushrooms (Lentinula edodes)

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in Journal of the Japanese Forest Society in 2024. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

Immune supportGut & microbiome

High relevance

Cordyceps · 2024 · Journal Article · International journal of biological macromolecules

Elucidation of antioxidant activities of intracellular and extracellular polysaccharides from Cordyceps militaris in vitro and their protective effects on ulcerative colitis in vivo.

In this study, we extracted the polysaccharides from C. militaris fruiting bodies (CFIPs), mycelial intracellular polysaccharides (CMIPs), and fermentation broth extracellular polysaccharides (CFEPs) to investigate their physicochemical properties, antioxidant capacities, and effects on oxazolone-induced zebrafish….

Immune supportMetabolic healthGut & microbiome

High relevance

Shiitake · 2024 · Journal Article · Journal for the Integrated Study of Dietary Habits

Evaluation of flavor components of shiitake mushroom (Lentinula edodes (Berk.) Pegler) by low-temperature cooking

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in Journal for the Integrated Study of Dietary Habits in 2024. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

Immune supportGut & microbiome

High relevance

Shiitake · 2024 · Journal Article · Mushroom Science and Biotechnology

Mapping of quantitative trait loci associated with temperature for fruiting body induction in Lentinula edodes (Shiitake mushroom)

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in Mushroom Science and Biotechnology in 2024. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

Immune supportGut & microbiome

High relevance

Cordyceps · 2024 · Research Article · Redox biology

SKN-1 is indispensable for protection against Aβ-induced proteotoxicity by a selenopeptide derived from Cordyceps militaris.

Oxidative stress (OS) and disruption of proteostasis caused by aggregated proteins are the primary causes of cell death in various diseases. Selenopeptides have shown the potential to control OS and alleviate inflammatory damage, suggesting promising therapeutic applications..

Immune supportEnergy & fatigue

High relevance

Cordyceps · 2023 · Systematic Review · Frontiers in pharmacology

Efficacy and safety of Ophiocordyceps sinensis in the treatment of Hashimoto's thyroiditis: a systematic review and meta-analysis.

Objective: To evaluate the efficacy and safety of Ophiocordyceps sinensis (OS) preparations for the treatment of Hashimoto's thyroiditis (HT). Methods: We searched eight databases to collect randomized controlled trials (RCTs) of OS combined with a low-iodine diet or levothyroxine for HT..

OncologyImmune support

High relevance

Mesima · 2023 · Systematic Review · International journal of biological macromolecules

Polysaccharides from Phellinus linteus: A systematic review of their extractions, purifications, structures and functions.

Phellinus linteus (P. linteus) is a famous Chinese medicine and has a long history in China.

OncologyImmune supportMetabolic healthLiver support

High relevance

Reishi · 2023 · Systematic Review · Food & function

Therapeutic potential and nutritional significance of Ganoderma lucidum - a comprehensive review from 2010 to 2022.

With a long history in traditional Asian medicine, Ganoderma lucidum (G. lucidum) is a mushroom species suggested to improve health and extend life.

OncologyImmune supportMetabolic healthGut & microbiome

High relevance

Reishi · 2026 · Review · Pharmaceuticals (Basel, Switzerland)

Anti-Inflammatory Potential of Ganoderma lucidum Triterpenes: A Systematic Review and Meta-Analysis of Preclinical Evidence.

Background: Ganoderma lucidum triterpenes are bioactive compounds with recognized anti-inflammatory, antitumor, and immunomodulatory properties. This systematic review synthesizes evidence regarding the anti-inflammatory activity of these triterpenes based on studies from the last two decades..

OncologyImmune supportLiver support

High relevance

Lion's Mane · 2026 · Review · International journal of molecular sciences

Beyond Neurotrophins: A Proposed Neurotrophic-Epigenetic Axis Mediated by Non-Coding RNA Networks for Hericium erinaceus Bioactives-A Hypothesis-Driven Review.

Hericium erinaceus (H. erinaceus), a medicinal mushroom, is a source of bioactive compounds with demonstrated neuroprotective potential.

Immune supportCognition & nerves

High relevance

Enoki · 2026 · Review · Journal of the science of food and agriculture

Biological activities and bioactive constituents of Flammulina velutipes: An updated systematic review.

Flammulina velutipes (enokitake) is an edible mushroom recognized for both its nutritional and medicinal properties. It exhibits a broad spectrum of biological activities, including antioxidant, anti-inflammatory, antitumor, immunomodulatory, and gut microbiota-regulating effects..

OncologyImmune supportGut & microbiome

High relevance

Reishi · 2026 · Review · International journal of biological macromolecules

Ganoderma lucidum polysaccharides target the gut-brain axis: Unveiling a novel mechanism for ameliorating aging-induced cognitive impairment and oxidative stress.

With the rapid progression of global population aging, the incidence of cognitive dysfunction-related disorders is steadily increasing. In recent years, growing attention has been directed toward the interaction between the gut microbiota and the central nervous system (CNS)..

Immune supportCognition & nervesGut & microbiome

High relevance

Lion's Mane · 2026 · Scoping Review · Chemistry & biodiversity

Hericenones From Hericium erinaceus (Bull.) Pers.: A Scoping Review of Structural Diversity and Health Benefits.

Hericium erinaceus (Bull.) Pers., an edible and medicinal mushroom, has garnered significant scientific interest due to its rich array of bioactive compounds. Extensive research has highlighted the pharmacological properties of its constituents, including neuroprotective, neurotrophic, immunomodulatory, and anticancer….

OncologyImmune supportCognition & nervesMetabolic health

High relevance

Chaga · 2026 · Review · International journal of biological macromolecules

Preparation, bioactivities, structure-activity relationships, applications, and safety concerns of Inonotus obliquus polysaccharides: A review.

Inonotus obliquus polysaccharides (IOPs) are β-glucan-rich heteropolysaccharides whose structural diversity underlies their immunomodulatory, antioxidant, and gut-organ-axis-mediated activities..

Immune supportEnergy & fatigueGut & microbiome

High relevance

Reishi · 2026 · Review · Phytotherapy research: PTR

Unlocking the Therapeutic Potential of Ganoderma lucidum: From Bioactive Compounds to Clinical Translation.

Ganoderma lucidum, a revered medicinal mushroom with a rich history in traditional East Asian medicine, has garnered significant scientific attention for its diverse pharmacological properties..

OncologyImmune supportLiver supportSkin & hydration

High relevance

Reishi · 2025 · Review · Food science & nutrition

A Review of Bioactive Components and Pharmacological Effects of Ganoderma lucidum.

Ganoderma lucidum, a distinguished traditional medicinal herb, has long been recognized for its purported benefits in promoting physical well-being, enhancing stamina, and boosting vitality. However, the mechanistic underpinnings of its antitumor activities and other therapeutic effects remain incompletely understood..

OncologyImmune supportEnergy & fatigue

High relevance

Reishi · 2025 · Review · International journal of biological macromolecules

A review of polysaccharides from Ganoderma lucidum: Preparation methods, structural characteristics, bioactivities, structure-activity relationships and potential applications.

Ganoderma lucidum (G. lucidum), commonly known as "fairy grass", is a saprophyte fungus belonging to the Polyporaceae family with a lengthy history of use as a food ingredient and traditional medicine in China.

OncologyImmune supportMetabolic health

High relevance

Zhu Ling · 2025 · Review · Food chemistry: X

A systematic review of advances in preparation, structures, bioactivities, structural-property relationships, and applications of Polyporus umbellatus polysaccharides.

Polyporus umbellatus (Pers.) Fries is an edible fungus species belonging to the Polygonaceae family. Polysaccharides, the predominant bioactive compounds in P.

Immune support

High relevance

Lion's Mane · 2025 · Review · Frontiers in nutrition

Advances in the extraction, purification, structural characterization, and elucidation of the biological functions of polysaccharides from Hericium erinaceus.

Hericium erinaceus has a high food and ornamental value and considerable benefits upon consumption and in research. The high polysaccharide content in H.

OncologyImmune supportMetabolic healthGut & microbiome

High relevance

Niu-Chang-Chih · 2025 · Review · ACS omega

Biological Functions and Synthesis of the Active Components in Antrodia camphorata.

As a fungus endemic to Taiwan, Antrodia camphorata contains a variety of medicinally active substances, such as polysaccharides, triterpenoids, maleic acid and succinic acid derivatives, and ubiquinone derivatives. A..

Immune supportMetabolic health

High relevance

Lion's Mane · 2025 · Review · International journal of biological macromolecules

Extraction, purification, structural characteristics, biological activities, modifications, and applications from Hericium erinaceus polysaccharides: A review.

Hericium erinaceus (Bull.) Pers. is a respected medicinal and edible fungus known for its outstanding nutritional profile.

OncologyImmune supportCognition & nervesGut & microbiome

High relevance

Lion's Mane · 2025 · Review · Food science & nutrition

Extraction, Structural Characterization and Biological Activities of Polysaccharides Derived From Hericium erinaceus.

Hericium erinaceus is acknowledged for its dual roles in medicinal and culinary contexts. The polysaccharides derived from H.

Immune supportMetabolic healthGut & microbiome

High relevance

Shiitake · 2025 · Review · International journal of molecular sciences

Lentinula edodes as a Source of Bioactive Compounds with Therapeutical Potential in Intestinal Inflammation and Colorectal Cancer.

Inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), is a rising global health issue. Chronic intestinal inflammation is an important risk factor for colorectal cancer (CRC)..

OncologyImmune supportGut & microbiome

High relevance

Yellow Morel · 2025 · Review · Natural product research

Morchella esculenta polysaccharides: a functional food with potential immunomodulatory properties.

Modern pharmacological research has demonstrated highly appreciated culinary mushrooms, Morchella esculenta. The soluble β glucans are immunostimulatory that is mediated through production of proinflammatory cytokines and activation of nuclear factor-kappa B (NF-κB), leading to phagocytosis and resident macrophage….

Immune supportEnergy & fatigueMetabolic health

High relevance

Zhu Ling · 2025 · Review · Engineering in life sciences

Polyporus umbellatus, A Precious Rare Fungus With Good Pharmaceutical and Food Value.

Polyporus umbellatus is a rare porous fungus that exhibits notable pharmacological activities. Particularly, due to its diuretic properties, it is considered an important source of targeted drugs for the treatment of kidney disease..

Immune support

High relevance

Reishi · 2025 · Review · Food science & nutrition

Potential Active Compounds of Ganoderma lucidum and Their Anticancer Effects: A Comprehensive Review.

The incidence and mortality rates of cancer patients continue to rise. Although many physical and chemical therapies, such as targeted tumor treatments, are effective against cancer, they are often associated with varying degrees of side effects..

OncologyImmune support

High relevance

Lion's Mane · 2025 · Review · International journal of biological macromolecules

Recent insights into Hericium erinaceus polysaccharides: Gastrointestinal, gut microbiota, microbial metabolites, overall health and structure-function correlation.

Hericium erinaceus polysaccharides (HEPs) have attracted significant interest due to their potential to support gastrointestinal health and modulate gut microbiota..

Immune supportCognition & nervesGut & microbiomeLiver support

High relevance

Oyster Mushroom · 2025 · Review · Molecules (Basel, Switzerland)

Structure-Forming Properties of Pleurotus ostreatus: A Promising Resource for Edible 3D Printing Applications.

Approximately 20-30% of cultivated oyster mushrooms (Pleurotus ostreatus) are classified as low grade due to morphological and visual imperfections or mechanical damage, representing significant waste in mushroom production systems. This review examines the structural and biochemical properties of P..

Immune supportLiver supportSkin & hydration

High relevance

Snow Fungus · 2025 · Review · Journal of food science

Structure, Function and Application of Tremella Fuciformis Polysaccharide: A Review.

Tremella fuciformis (TF) is a valuable edible fungus rich in various nutrients, with TF polysaccharide (TFP) as its primary bioactive component. Extensive studies have demonstrated that TFP exhibits significant bioactivities, including antioxidant, antitumor, immunomodulatory, memory-enhancing, anti-inflammatory,….

OncologyImmune supportCognition & nervesMetabolic health

High relevance

Lion's Mane · 2025 · Review · Psychopharmacology bulletin

Theoretical Potential of Hericium Erinaceus Supplementation as an Add-On to Antipsychotics in Chronic and Treatment-Resistant Schizophrenia.

Schizophrenia is a serious mental illness that is a leading cause of disability worldwide. While antipsychotic agents are the most effective medications, up to one-third of patients experience treatment resistance, and approximately one-sixth of patients experience ultra-resistant illness..

Immune supportCognition & nervesGut & microbiome

High relevance

Reishi · 2025 · Review · Chinese herbal medicines

Unraveling bioactive potential and production in Ganoderma lucidum through omics and machine learning modeling.

Ganoderma lucidum, a medicinal mushroom renowned for its production of a diverse array of compounds, accounts for the pharmacological effects including anti-inflammatory, antioxidant, immunomodulatory, and anticancer characteristics..

OncologyImmune supportCognition & nerves

High relevance

Almond Mushroom · 2024 · Review · Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

[Research progress on structures, activities, and biosynthesis of blazeispirol compounds from Agaricus blazei].

Agaricus blazei is a rare medicinal and edible fungus with a crispy taste and delicious flavor. Both fruiting body and mycelium are rich in polysaccharides, sterols, terpenoids, peptides, lipids, polyphenols, and other active ingredients, which have strong pharmacological activities such as anti-tumor, lipid-lowering,….

OncologyImmune supportMetabolic healthGut & microbiome

High relevance

Chaga · 2024 · Review · Fungal biology and biotechnology

A review on the cultivation, bioactive compounds, health-promoting factors and clinical trials of medicinal mushrooms Taiwanofungus camphoratus, Inonotus obliquus and Tropicoporus linteus.

Medicinal mushrooms, such as Taiwanofungus camphoratus, Inonotus obliquus, and Tropicoporus linteus, have been used in traditional medicine for therapeutic purposes and promotion of overall health in China and many East Asian countries for centuries..

OncologyImmune supportMetabolic healthRespiratory

High relevance

Reishi · 2024 · Review · Chinese herbal medicines

Bioactive components, pharmacological properties and underlying mechanism of Ganoderma lucidum spore oil: A review.

Ganoderma lucidum is a Chinese medicinal fungus with a long history of use in healthcare and disease treatment. G.

OncologyImmune supportCognition & nervesMetabolic health

High relevance

Reishi · 2024 · Review · Heliyon

Bioactivities and industrial standardization status of Ganoderma lucidum: A comprehensive review.

Ganoderma lucidum (GL) is a potent source of bioactive compounds with diverse nutritional and pharmacological benefits. Its popularity as a dietary supplement, herbal remedy, and wellness product is steadily on the rise..

OncologyImmune supportMetabolic healthGut & microbiome

High relevance

Reishi · 2024 · Review · The Journal of pharmacy and pharmacology

Ganoderma lucidum triterpenoids investigating their role in medicinal applications and genomic protection.

OBJECTIVES: Ganoderma lucidum (GL) is a white rot fungus widely used for its pharmacological properties and health benefits. GL consists of several biological components, including polysaccharides, sterols, and triterpenoids..

OncologyImmune supportMetabolic health

High relevance

Reishi · 2024 · Review · Heliyon

Ganoderma lucidum: Insight into antimicrobial and antioxidant properties with development of secondary metabolites.

Ganoderma lucidum is a versatile mushroom. Polysaccharides and triterpenoids are the major bioactive compounds and have been used as traditional medicinal mushrooms since ancient times.

OncologyImmune supportMetabolic health

High relevance

Reishi · 2024 · Review · International journal of biological macromolecules

Ganoderma lucidum: Multifaceted mechanisms to combat diabetes through polysaccharides and triterpenoids: A comprehensive review.

Diabetes is a chronic metabolic disorder. Diabetes complications can affect many organs and systems in the body.

Immune supportMetabolic health

High relevance

Maitake · 2024 · Review · International journal of biological macromolecules

Grifola frondosa polysaccharides: A review on structure/activity, biosynthesis and engineering strategies.

Polysaccharides are the main polymers in edible fungi Grifola frondosa, playing a crucial role in the physiology and representing the healthy benefits for humans. Recent efforts have well elucidated the fine structures and biological functions of G.

Immune support

High relevance

Mesima · 2024 · Review · International journal of biological macromolecules

Phellinus linteus polysaccharides: A review on their preparation, structure-activity relationships, and drug delivery systems.

Phellinus linteus polysaccharides exhibit antitumor, immunomodulatory, anti-inflammatory, and antioxidant properties, mitigate insulin resistance, and enhance the diversity and abundance of gut microbiota. However, the bioactivities of P..

OncologyImmune supportMetabolic healthGut & microbiome

High relevance

Reishi · 2024 · Review · Frontiers in microbiology

Regulatory effect of Ganoderma lucidum and its active components on gut flora in diseases.

Driven by the good developmental potential and favorable environment at this stage, Ganoderma lucidum is recognized as a precious large fungus with medicinal and nutritional health care values. Among them, polysaccharides, triterpenoids, oligosaccharides, trace elements, etc.

Immune supportMetabolic healthGut & microbiome

High relevance

Enoki · 2024 · Review · International journal of biological macromolecules

Research progress and future development potential of Flammulina velutipes polysaccharides in the preparation process, structure analysis, biology, and pharmacology: A review.

In recent years, Flammulina velutipes (F. velutipes) has attracted consequential attention in various research fields due to its rich composition of proteins, vitamins, amino acids, polysaccharides, and polyphenols.

Immune supportSkin & hydration

High relevance

Reishi · 2024 · Review · Life (Basel, Switzerland)

Research Progress on the Biological Activity of Ganoderic Acids in Ganoderma lucidum over the Last Five Years.

Ganoderma lucidum (G. lucidum) is a traditional edible and medicinal mushroom in China.

OncologyImmune supportCognition & nervesLiver support