MycoData

Triterpenes (GFTs) are the main secondary metabolites of Grifola frondosa, which is a famous porous fungus with multiple biological actions. To enhance the yield of GFTs, the parameters for ultrasound-assisted extraction (UAE) of GFTs were first optimized..

Energy & fatigue

High relevance

Oyster Mushroom · 2025 · Journal Article · World J Microbiol Biotechnol

Underlying the early signaling and gene expression of Pleurotus ostreatus mycelia during injury response

Plants and animals have demonstrated conserved damage defense systems, but the injury response mechanisms in fungi remain largely unexplored. In this study, we investigate the early defensive mechanisms activated by mechanical damage in the basidiomycota Pleurotus ostreatus..

Energy & fatigueSkin & hydration

High relevance

Oyster Mushroom · 2025 · Journal Article · World journal of microbiology & biotechnology

Underlying the early signaling and gene expression of Pleurotus ostreatus mycelia during injury response.

Energy & fatigueSkin & hydration

High relevance

Reishi · 2025 · Journal Article · Journal of pharmaceutical and biomedical analysis

UPLC-Q-TOF/MS-based study on chemical composition, in vivo metabolites, and tissue distribution of ethanol extract of Ganoderma lucidum.

Ganoderma lucidum (G. lucidum), a medicinal fungus, exhibits diverse pharmacological effects against many diseases.

OncologyEnergy & fatigueGut & microbiomeLiver support

High relevance

Enoki · 2024 · Journal Article · Food & function

A novel neuroprotective peptide YVYAETY identified and screened from Flammulina velutipes protein hydrolysates attenuates scopolamine-induced cognitive impairment in mice.

Flammulina velutipes protein hydrolysates are known for their abundant amino acids and excellent developmental values. This study aimed to identify and screen neuroprotective peptides from F..

OncologyCognition & nervesEnergy & fatigueGut & microbiome

High relevance

Reishi · 2024 · Journal Article · Environmental science and pollution research international

Atmosphere-dependent combustion of Ganoderma lucidum biomass toward its enhanced transformability into green energy.

Globally, the circular efficiency of biomass resources has become a priority due to the depletion and negative environmental impacts of fossil fuels. This study aimed to quantify the atmosphere-dependent combustion of Ganoderma lucidum (GL) biomass and its thermodynamic and kinetic parameters toward enhancing its….

Energy & fatigue

High relevance

Yellow Morel · 2024 · Journal Article · Food and chemical toxicology: an international journal published for the British Industrial Biological Research Association

Bioactive extract of Morchella esculenta ameliorates cyclophosphamide-induced mitochondrial dysfunction and cardiotoxicity by modulating KEAP1/NRF2 and pro-inflammatory genes expression.

Prevention of anticancer drugs-induced cardiotoxicity remains an imperative area of oncology research as it continues to be a major challenge in cancer chemotherapy..

OncologyImmune supportEnergy & fatigue

High relevance

Reishi · 2024 · Research Article · Molecules (Basel, Switzerland)

Carbonized Ganoderma Lucidum/V2O3 Composites as a Superior Cathode for High-Performance Aqueous Zinc-Ion Batteries.

In response to the suboptimal electrochemical performance of low-valence vanadium oxides, Ganoderma lucidum biomass-derived carbon@V2O3 (V2O3@CGL) composites were prepared by evaporative self-assembly technology and high-temperature calcination..

Energy & fatigue

High relevance

Reishi · 2024 · Journal Article · Food Research International

Combined NMR and MS-based metabonomics and real-time PCR analyses reveal dynamic metabolic changes of Ganoderma lucidum during fruiting body growing

Ganoderma lucidum (G. lucidum) is a rare medicinal fungus with various beneficial properties.

OncologyEnergy & fatigueMetabolic healthLiver support

High relevance

Reishi · 2024 · Journal Article · Food research international (Ottawa, Ont.)

Combined NMR and MS-based metabonomics and real-time PCR analyses reveal dynamic metabolic changes of Ganoderma lucidum during fruiting body growing.

Ganoderma lucidum (G. lucidum) is a rare medicinal fungus with various beneficial properties.

OncologyEnergy & fatigueMetabolic healthLiver support

High relevance

Reishi · 2024 · Journal Article · Computational biology and chemistry

Computational exploration of Ganoderma lucidum metabolites as potential anti-atherosclerotic agents: Insights from molecular docking and dynamics simulations.

Ganoderma lucidum is a unique form of fungus utilized in Chinese medicine for various therapies as it exhibits a wide range of pharmacological activity. In this study, the purpose is to evaluate the possible drug-like qualities of the metabolites of G..

Immune supportEnergy & fatigue

High relevance

Shiitake · 2024 · Journal Article · Ecotoxicology and environmental safety

Detoxification of tetracycline and synthetic dyes by a newly characterized Lentinula edodes laccase, and safety assessment using proteomic analysis.

Fungal laccase has strong ability in detoxification of many environmental contaminants. A putative laccase gene, LeLac12, from Lentinula edodes was screened by secretome approach..

Energy & fatigue

High relevance

Oyster Mushroom · 2024 · Journal Article · Food science and technology international = Ciencia y tecnologia de los alimentos internacional

Development of novel heat-treated sausage with Pleurotus ostreatus: Low energy, enhanced bioactivity, reduced amount of meat and fat.

The use of Pleurotus ostreatus to reduce calories and increase bioactivity in processed meat products is an increasingly common practice. In this study, a novel sausage containing P..

Energy & fatigue

High relevance

Enoki · 2024 · Journal Article · International journal of food science & technology

Effect of extraction and purification on the structure and activity of Flammulina velutipes polysaccharides: a review

Flammulina velutipes (F. velutipes) is one of the most widely consumed edible mushrooms worldwide.

Immune supportCognition & nervesEnergy & fatigueMetabolic health

High relevance

Almond Mushroom · 2024 · Research Article · Animal bioscience

Effects of dietary supplementation of polysaccharide from Agaricus blazei Murr on productive performance, egg quality, blood metabolites, intestinal morphology and microbiota of Korean quail.

OBJECTIVE: This study aimed to investigate the effects of dietary supplementation with Agaricus blazei polysaccharide (ABP) at varying concentrations on the performance, egg quality, blood biochemistry, intestinal morphology, and microflora of quail..

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

High relevance

Enoki · 2024 · Research Article · Frontiers in microbiology

Effects of Flammulina velutipes mushroom residues on growth performance, apparent digestibility, serum biochemical indicators, rumen fermentation and microbial of Guizhou black goat.

INTRODUCTION: The primary objective of the current study was to evaluate the effects of Flammulina velutipes mushroom residue (FVMR) in a fermented total mixed ration (FTMR) diet on the fattening effect and rumen microorganisms in Guizhou black male goats..

Immune supportEnergy & fatigueGut & microbiome

High relevance

Reishi · 2024 · Journal Article · Journal of applied poultry research

Effects of Ganoderma Lucidum supplementation on the growth performance, biochemical blood parameters, antioxidant and immunity status, and meat quality in slow-growing broilers

Ganoderma Lucidum (G. lucidum) is an edible mushroom and it has been used as a medicinal fungus for centuries.

OncologyImmune supportEnergy & fatigueMetabolic health

High relevance

Lion's Mane · 2024 · Journal Article · Comparative biochemistry and physiology. Toxicology & pharmacology: CBP

Effects of Hericium erinaceus polysaccharide in porcine IPEC-J2 intestinal epithelial cells against apoptosis induced by oxidative stress.

This study was intended to investigate whether Hericium erinaceus polysaccharides (HEP) prevent oxidative stress and apoptosis of intestinal porcine epithelial cells from jejunum (IPEC-J2 cells) induced by hydrogen peroxide (H2O2). Crude HEP were extracted and purified by chromatography..

OncologyImmune supportEnergy & fatigueGut & microbiome

High relevance

Oyster Mushroom · 2024 · Journal Article · Environmental research

Effects of initial corncob particle size on the short-term composting for preparation of cultivation substrates for Pleurotus ostreatus.

The short-term composting based on corncob for preparing Pleurotus ostreatus cultivation medium originated from agricultural production practices and so lacked systematic investigation..

Energy & fatigueGut & microbiome

High relevance

Chaga · 2024 · Research Article · Frontiers in pharmacology

Effects of Inonotus obliquus on ameliorating podocyte injury in ORG mice through TNF pathway and prediction of active compounds.

BACKGROUND: Podocyte injury is a common pathologic mechanism in diabetic kidney disease (DKD) and obesity-related glomerulopathy (ORG). Our previous study confirmed that Inonotus obliquus (IO) improved podocyte injury on DKD rats..

Immune supportCognition & nervesEnergy & fatigueMetabolic health

High relevance

Enoki · 2024 · Research Article · Journal of fungi (Basel, Switzerland)

Effects of Light on the Fruiting Body Color and Differentially Expressed Genes in Flammulina velutipes.

Light plays vital roles in fungal growth, development, reproduction, and pigmentation. In Flammulina velutipes, the color of the fruiting body exhibits distinct changes in response to light; however, the underlying molecular mechanisms remain unknown.

Energy & fatigueMetabolic health

High relevance

Reishi · 2024 · Journal Article · Phytochemical analysis: PCA

Efficient and fast screening and separation based on computer-aided screening and complex chromatography methods for lipoxygenase inhibitors from Ganoderma lucidum.

INTRODUCTION: Accurate screening and targeted preparative isolation of active substances from natural medicines have long been technical challenges in natural medicine research..

Cognition & nervesEnergy & fatigue

High relevance

Lion's Mane · 2024 · Journal Article · International journal of biological macromolecules

Electric-field-sensitive hydrogel based on pineapple peel oxidized hydroxyethyl cellulose/gelatin/Hericium erinaceus residues chitosan and its study in curcumin delivery.

This study focused on synthesis of innovative hydrogels with electric field response from modified pineapple peel cellulose and hericium erinaceus chitosan and gelatin based on Schiff base reaction..

Energy & fatigueLiver support

High relevance

Oyster Mushroom · 2024 · Journal Article · World J Microbiol Biotechnol

Enhanced degradation of phototreated recycled and unused low-density polyethylene films by Pleurotus ostreatus

Polyethylene, one of the most used petroleum-derived polymers, causes serious environmental pollution. The ability of Pleurotus ostreatus to degrade UV-treated and untreated recycled and unused (new) low-density polyethylene (LDPE) films was studied..

Energy & fatigue

High relevance

Oyster Mushroom · 2024 · Journal Article · World journal of microbiology & biotechnology

Enhanced degradation of phototreated recycled and unused low-density polyethylene films by Pleurotus ostreatus.

Energy & fatigue

High relevance

Reishi · 2024 · Journal Article · Journal of food science

Enhancement of exercise-induced fatigue alleviation and liver selenium regulation through in situ nanoselenium synthesis by Lactobacillus rhamnosus cells, empowered by Ganoderma lucidum spore loading.

Given the increasing awareness of the negative effects of fatigue on daily activities, mental health, and quality of life, antifatigue supplements are becoming increasingly popular among consumers. Selenium has been found to have antifatigue potential in high dosage, but may cause toxicity effects to the body..

Energy & fatigueGut & microbiomeLiver support

High relevance

Turkey Tail · 2024 · Journal Article · Journal of biotechnology

Enhancement of the biological activity of hydroxytyrosol through its oxidation by laccase from Trametes versicolor.

The laccase-catalyzed oxidation of hydroxytyrosol (HT) towards the formation of its bioactive oligomer derivatives was investigated. The biocatalytic oligomerization was catalyzed by laccase from Trametes versicolor in aqueous or various water-miscible organic solvents and deep eutectic solvent (DES)-based media..

OncologyEnergy & fatigueSkin & hydration

High relevance

Niu-Chang-Chih · 2024 · Journal Article · Innovative Food Science and Emerging Technologies

Enhancing submerged fermentation of Antrodia camphorata by low-frequency alternating magnetic field

This work aimed to investigate the impact of low-frequency (30–300 kHz) alternating magnetic field (LF-AMF) on enhancing submerged fermentation of Antrodia camphorata (A. camphorata), a basidiomycete fungus..

Immune supportEnergy & fatigueSkin & hydration

High relevance

Shiitake · 2024 · Journal Article · Heliyon

Enhancing yields of Pleurotus ostreatus and Lentinula edodes mushrooms using water hyacinth (Eichhornia crassipes [Mart.] Solms) supplemented with locally available feedstock as substrate

This study assessed the performance of Pleurotus ostreatus and Lentinula edodes mushrooms on a variety of substrate combinations. Water hyacinth, rice husk, and cow dung were employed as substrates.

Energy & fatigue

High relevance

Shiitake · 2024 · Research Article · Heliyon

Enhancing yields of Pleurotus ostreatus and Lentinula edodes mushrooms using water hyacinth (Eichhornia crassipes [Mart.] Solms) supplemented with locally available feedstock as substrate.

This study assessed the performance of Pleurotus ostreatus and Lentinula edodes mushrooms on a variety of substrate combinations. Water hyacinth, rice husk, and cow dung were employed as substrates.

Energy & fatigue

High relevance

Enoki · 2024 · Journal Article · International journal of biological macromolecules

Extraction of chitin from flammulina velutipes waste: A low-concentration acid pretreatment and aspergillus Niger fermentation approach.

In recent years, with the booming of the edible mushroom industry, chitin production has become increasingly dependent on fungi and other non-traditional sources. Fungal chitin has advantages including superior performance, simpler separation processes, abundant raw materials, and the absence of shellfish allergens..

Energy & fatigueMetabolic health

High relevance

Reishi · 2024 · Research Article · iScience

Ganoderma lucidum extract attenuates corticotropin-releasing hormone-induced cellular senescence in human hair follicle cells.

Corticotropin-releasing hormone (CRH) is a key mediator in stress-induced hair growth inhibition. Here, we investigated the impact of stress-induced senescence and evaluated the potential of Ganoderma lucidum (GL) extract in mitigating CRH-induced senescence in human hair follicle cells (hHFCs)..

Energy & fatigue

High relevance

Reishi · 2024 · Journal Article · International journal of biological macromolecules

Ganoderma lucidum polysaccharide hydrogel accelerates diabetic wound healing by regulating macrophage polarization.

Impaired macrophage polarization or the high levels of reactive oxygen species (ROS) produced by high glucose conditions and bacterial infection are the primary factors that make healing diabetic wounds difficult..

Immune supportEnergy & fatigueMetabolic healthSkin & hydration

High relevance

Reishi · 2024 · Research Article · Antioxidants (Basel, Switzerland)

Ganoderma lucidum Spore Powder Alleviates Metabolic-Associated Fatty Liver Disease by Improving Lipid Accumulation and Oxidative Stress via Autophagy.

Lipid accumulation and oxidative stress, which could be improved by autophagy, are the "hits" of metabolic-associated fatty liver disease (MAFLD). Ganoderma lucidum spore powder (GLSP) has the effect of improving liver function..

Energy & fatigueMetabolic healthLiver support

High relevance

Reishi · 2024 · Journal Article · Free radical biology & medicine

Glsirt1-mediated deacetylation of GlCAT regulates intracellular ROS levels, affecting ganoderic acid biosynthesis in Ganoderma lucidum.

Lysine acetylation is a reversible, dynamic protein modification regulated by lysine acetyltransferases and deacetylases. However, in Basidiomycetes, the extent of lysine acetylation of nonhistone proteins remains largely unknown..

Energy & fatigue

High relevance

Maitake · 2024 · Journal Article · Food Research International

Grifola frondosa extract as a fetal bovine serum supplement for the culture of bovine muscle satellite cells under low serum conditions

Expensive fetal bovine serum (FBS) is a major obstacle to the production of cultivated meat. However, because FBS substitutes do not sufficiently induce cell proliferation, a good alternative is to reduce the amount of FBS and use ingestible additives to promote cell proliferation..

Energy & fatigue

High relevance

Maitake · 2024 · Journal Article · Food research international (Ottawa, Ont.)

Grifola frondosa extract as a fetal bovine serum supplement for the culture of bovine muscle satellite cells under low serum conditions.

Energy & fatigue

High relevance

Oyster Mushroom · 2024 · Research Article · Mycobiology

Growth and Yield Performance of Pleurotus ostreatus Cultivated on Agricultural Residues.

Food insecurity and malnutrition are among the major problems in most developing nations recently. Mushroom cultivation is one of the promising strategies to overcome these challenges.

Energy & fatigueGut & microbiome

High relevance

Reishi · 2024 · Research Article · Redox biology

Hydrogen sulfide maintains mitochondrial homeostasis and regulates ganoderic acids biosynthesis by SQR under heat stress in Ganoderma lucidum.

Hydrogen sulfide (H2S) has recently been recognized as an important gaseous transmitter with multiple physiological effects in various species. Previous studies have shown that H2S alleviated heat-induced ganoderic acids (GAs) biosynthesis, an important quality index of Ganoderma lucidum..

Energy & fatigue

High relevance

Reishi · 2024 · Research Article · Molecules (Basel, Switzerland)

Improvement of Echinacea purpurea and Ganoderma lucidum Extracts with Cell Model on Influenza A/B Infection.

Since 2019, COVID-19 has been raging around the world. Respiratory viral infectious diseases such as influenza and respiratory syncytial virus (RSV) infection are also prevalent, with influenza having the ability to cause seasonal pandemics..

OncologyImmune supportEnergy & fatigueRespiratory

High relevance

Oyster Mushroom · 2024 · Journal Article · The Science of the total environment

In situ mycoremediation of acid rain and heavy metals co-contaminated soil through microbial inoculation with Pleurotus ostreatus.

The combined pollution of acid rain and heavy metals in soil is a pressing environmental problem, especially in the regions with large-scale heavy industrial production activities..

Energy & fatigue

High relevance

Reishi · 2024 · Research Article · Journal of pharmaceutical analysis

Integrating transcriptomics, metabolomics, and network pharmacology to investigate multi-target effects of sporoderm-broken spores of Ganoderma lucidum on improving HFD-induced diabetic nephropathy rats.

Diabetes mellitus (DM) is a major metabolic disease endangering global health, with diabetic nephropathy (DN) as a primary complication lacking curative therapy. Sporoderm-broken spores of Ganoderma lucidum (GLP), an herbal medicine, has been used for the treatment of metabolic disorders..

Immune supportEnergy & fatigueMetabolic health

High relevance

Snow Fungus · 2024 · Journal Article · Talanta

Integration of electronic nose, electronic tongue, and colorimeter in combination with chemometrics for monitoring the fermentation process of Tremella fuciformis.

This study proposes an efficient method for monitoring the submerged fermentation process of Tremella fuciformis (T. fuciformis) by integrating electronic nose (e-nose), electronic tongue (e-tongue), and colorimeter sensors using a data fusion strategy..

Immune supportCognition & nervesEnergy & fatigue

High relevance

Snow Fungus · 2024 · Research Article · Foods (Basel, Switzerland)

Investigating the Respiratory and Energy Metabolism Mechanisms behind ε-Poly-L-lysine Chitosan Coating's Improved Preservation Effectiveness on Tremella fuciformis.

Freshly harvested Tremella fuciformis contains high water content with an unprotected outer surface and exhibits high respiration rates, which renders it prone to moisture and nutrient loss, leading to decay during storage..

Energy & fatigueMetabolic healthRespiratory

High relevance

Oyster Mushroom · 2024 · Journal Article · Bioresource technology

Investigation of pre-treatment techniques on spent substrate of Pleurotus ostreatus for enhanced biobutanol production using Clostridium acetobutylicum MTCC 11274.

Addressing global energy demand, researchers sought eco-friendly biobutanol production from lignocellulosic waste biomass. In the present research work, five different pre-treatment methods viz., Microwave, Ultrasound, Alkali, Acid, and Hybrid, were investigated to explore its biobutanol production potential by….

Energy & fatigue

High relevance

Maitake · 2024 · Journal Article · Journal of the science of food and agriculture

Isolation and identification of active components from Grifola frondosa and its anti-EV71 virus effect.

BACKGROUND: It is reported that anti-enterovirus 71 (EV71) drugs have some side effects on human health. Notably, fungi plays a crucial role in promoting human health and anti-virus.

OncologyEnergy & fatigueRespiratory

High relevance

Maitake · 2024 · Journal Article · Journal of the science of food and agriculture

Isolation and identification of active components from Grifola frondosa and its anti‐EV71 virus effect

BACKGROUND: It is reported that anti‐enterovirus 71 (EV71) drugs have some side effects on human health. Notably, fungi plays a crucial role in promoting human health and anti‐virus.

OncologyEnergy & fatigueRespiratory

High relevance

Enoki · 2024 · Journal Article · Journal of agricultural and food chemistry

Lipidomic Profiling of Flammulina velutipes (Curtis) Singer (Agaricomycetes) through Ultra-Performance Liquid Chromatography Coupled with Quadrupole Time-of-Flight Mass Spectrometry: Examining Lipid Dynamics Changes during Fruiting Body Formation and Development.

Flammulina velutipes (enokitake) is widely recognized for its nutritional and medicinal properties. Understanding the biochemical processes, such as lipid metabolism during fruiting body formation, is essential for enhancing mushroom cultivation and utilization..

Energy & fatigueMetabolic health

High relevance

Oyster Mushroom · 2024 · Research Article · Foods (Basel, Switzerland)

Optimization of Mushroom (Agaricus bisporus and Pleurotus ostreatus) By-Products Processing for Prospective Functional Flour Development.

Stems are a major by-product of mushroom production. This study optimizes the transformation of Agaricus bisporus stems (ABS) and Pleurotus ostreatus stems (POS) into flour.

Energy & fatigueSkin & hydration

High relevance

Mesima · 2024 · Journal Article · Nanoscale

Oral exosome-like nanovesicles from Phellinus linteus suppress metastatic hepatocellular carcinoma by reactive oxygen species generation and microbiota rebalancing.

The biomedical application of nanotechnology in cancer treatment has demonstrated significant potential for improving treatment efficiencies and ameliorating adverse effects..

OncologyEnergy & fatigueGut & microbiomeLiver support