MycoData

Immune supportCognition & nerves

Oyster Mushroom · 2024 · Research Article · Current issues in molecular biology

Evaluation of the Influence of Varied Juncao Grass Substrates on Physiological and Enzymatic Reactions of Pleurotus ostreatus.

Pleurotus ostreutus is one of the world's most commonly consumed mushrooms. The cultivation of mushrooms using wood resources usually results in environmental issues such as deforestation..

Reishi · 2024 · Journal Article · Heliyon

Evaluation of the phytochemical, bioactive compounds and descriptive sensory of encapsulated lingzhi (Ganoderma lucidum) extracts with combined wall materials for masking effect on the perception of off-flavour and bitterness

Lingzhi mushroom (Ganoderma lucidum) is known as a medicinal mushroom that can be utilized in various functional foods available in the market, including powders, dietary supplements, and tea. However, its use is limited due to factors such as bitterness, flavour, and astringency..

Reishi · 2024 · Research Article · Heliyon

Evaluation of the phytochemical, bioactive compounds and descriptive sensory of encapsulated lingzhi (Ganoderma lucidum) extracts with combined wall materials for masking effect on the perception of off-flavour and bitterness.

Oyster Mushroom · 2024 · Preprint · journal metadata

Evaluation of wheatstraw, sawdust, banana fronds, maize cobs and cotton hulls substrate combinations for Pleurotus ostreatus cultivation.

Abstract The yield and quality of oyster mushroom is largely dependent on the chemical and nutritional content of the substrate. The objective of the study was to determine the effect of different individual substrates and substrate combinations on the perfomance of P.ostreatus for growth and sustainable development….

Energy & fatigueMetabolic health

Cordyceps · 2024 · Journal Article · International journal of medicinal mushrooms

Evidence for Regulation of Cordycepin Biosynthesis by Transcription Factors Krüppel-Like Factor 4 and Retinoid X Receptor Alpha in Caterpillar Medicinal Mushroom Cordyceps militaris (Ascomycetes).

Cordyceps militaris, Chinese traditional medicinal fungus, has many bioactive properties. Cordycepin (3'-deoxyadenosine) is a major bioactive component of C.

Cordyceps · 2024 · Research Article · International journal of molecular sciences

Expanded Gene Regulatory Network Reveals Potential Light-Responsive Transcription Factors and Target Genes in Cordyceps militaris.

Cordyceps militaris, a fungus widely used in traditional Chinese medicine and pharmacology, is recognized for its abundant bioactive compounds, including cordycepin and carotenoids..

Cognition & nerves

Chaga · 2024 · Journal Article · Doklady biological sciences: proceedings of the Academy of Sciences of the USSR, Biological sciences sections

Experimental Infection of Small-Diameter Trees with Chaga (Inonotus obliquus) in a Postagrogenous Birch Forest.

In the Plyussky district of the Pskov region, an experiment was carried out to infect birch trees with the Chaga pathogen Inonotus obliquus in an 18-year-old postagrogenic birch forest..

Immune supportSkin & hydration

Oyster Mushroom · 2024 · Research Article · Journal of pharmacy & bioallied sciences

Exploring the Role of Pleurotus Ostreatus as an Ointment Formulation in Inducing Wound Healing in Mice Skin.

BACKGROUND: Natural compounds rich in secondary metabolites have gained attention as alternative therapies for wound healing due to their potential advantages over conventional treatments..

OncologyImmune supportEnergy & fatigue

Reishi · 2024 · Review · Journal of clinical medicine

Exploring the Therapeutic Potential of Ganoderma lucidum in Cancer.

Triterpenoids, such as ganoderic acid, and polysaccharides, including β-D-glucans, α-D-glucans, and α-D-mannans, are the main secondary metabolites of the medicinal fungus Ganoderma lucidum..

Metabolic healthLiver support

Oyster Mushroom · 2024 · Research Article · Foods (Basel, Switzerland)

Exploring Therapeutic Potential of Pleurotus ostreatus and Agaricus bisporus Mushrooms against Hyperlipidemia and Oxidative Stress Using Animal Model.

The mushrooms oyster (Pleurotus ostreatus) and white button (Agaricus bisporus) contain bioactive compounds that have potential beneficial effects on hypercholesterolemia and cardiovascular diseases..

Oyster Mushroom · 2024 · Research Article · Frontiers in microbiology

Exploring time-killing and biofilm inhibition potential of bioactive proteins extracted from two varieties of Pleurotus ostreatus.

INTRODUCTION: Dental caries, caused by oral microbial pathogens, are a global health concern, further exacerbated by the presence of methicillin-resistant Staphylococcus aureus (MRSA)..

Immune supportGut & microbiome

Shiitake · 2024 · Journal Article · International journal of biological macromolecules

Extraction of chitin-glucan complex from shiitake (Lentinula edodes) fruiting bodies using natural deep eutectic solvents and its prebiotic potential.

Chitin-glucan complex (CGC) is an emerging novel prebiotic with numerous physiological activities in amelioration of clinical manifestations. In the present work, natural deep eutectic solvent (NADES), ultrasonication, and submerged fermentation using probiotic microorganisms were deployed for the extraction of CGC….

Cordyceps · 2024 · Journal Article · Industrial crops and products

Extraction, structural identification and anti-tumor activity of two Cordyceps militaris polysaccharides evaluated by S180 tumor-bearing mice

In this study, we extracted and isolated two polysaccharides with molecular weights of 2.28 × 10⁴ Da and 2.71 × 10³ Da from Cordyceps militaris, named CMP-90 and CMP-E, respectively..

OncologyImmune support

Shiitake · 2024 · Journal Article · Journal of wood science

Factors affecting the cesium transfer factor to shiitake (Lentinula edodes) cultivated in sawdust medium

The transfer factor (TF) of radioactive cesium-137 (¹³⁷Cs) to shiitake (Lentinula edodes) cultivated on bed logs varies greatly. Therefore, the present study investigated which factors affect the TF using stable cesium-133 (¹³³Cs) and sawdust medium with 5% rice bran as a model, which had similar ¹³³Cs TFs to bed-log….

Shiitake · 2024 · Research Article · Food chemistry: X

Feasibility analysis on the application of the Maillard reaction in developing Lentinula edodes umami seasoning: Based on the umami substances, sensory quality, physicochemical properties of the products.

To elucidate the feasibility of applying the Maillard reaction (MR) to the development of Lentinula edodes umami seasoning, this study quantitatively analyzed the main umami substances in the products and evaluated their sensory quality..

Cordyceps · 2024 · Systematic Review · Renal failure

Fermented Ophiocordyceps sinensis mycelium products for preventing contrast-associated acute kidney injury: a systematic review of randomized controlled trials.

BACKGROUND: To evaluate the efficacy, effectiveness and safety of fermented Ophiocordyceps sinensis mycelium (FOSM) products for preventing contrast-associated acute kidney injury (CA-AKI)..

Oyster Mushroom · 2024 · Journal Article · Anais da Academia Brasileira de Ciencias

First report of Penicillium brevicompactum causing disease in Pleurotus ostreatus.

Oyster mushroom (Pleurotus ostreatus) is the second most produced mushroom globally, but increased production is linked to new diseases. This study reports the first occurrence of Penicillium brevicompactum on P.

Cordyceps · 2024 · Journal Article · Phytochemistry

Five undescribed cyclopeptides from Cordyceps militaris.

Ustiloxins I-M (1-5), five undescribed cyclopeptides bearing a 15-membered macrocyclic skeleton, were isolated from Cordyceps militaris. The structures of 1 and 5 were identified by spectroscopic and crystallographic methods, whereas the structures of 2-4 were assigned by spectroscopic and computational approaches..

Oncology

Energy & fatigueSkin & hydration

Shiitake · 2024 · Journal Article · Journal of wood science

Fuel and material utilization of a waste shiitake (Lentinula edodes) mushroom bed derived from hardwood chips I: characteristics of calorific value in terms of elemental composition and ash content

To understand the fuel characteristics of a waste shiitake mushroom bed derived from hardwood chips, the moisture content at the time of disposal and after 1 month, as well as its calorific value, ash content, and elemental composition, were investigated..

Snow Fungus · 2024 · Research Article · Molecules (Basel, Switzerland)

Functionalities of Tremella fuciformis Polysaccharides Modified with Gallic Acid.

This research aimed to modify polysaccharides extracted from the edible mushroom Tremella fuciformis with gallic acid (GA) and to complex them with zinc ions. The functionalities of the modified Tremella fuciformis polysaccharides (TFPs) were investigated..

Metabolic healthGut & microbiomeSkin & hydration

Reishi · 2024 · Preprint · journal metadata

Ganoderma lucidum alleviates kidney aging by modulating gut microbiota

Background Ganoderma lucidum, a renowned traditional Chinese medicine known for its multiple health benefits, including anti-aging effect, has the ability to influence gut microbiota. However, its specific role in alleviating aging via gut microbiota has not been thoroughly investigated..

Reishi · 2024 · Randomized Controlled Trial · The British journal of nutrition

Ganoderma lucidum dry extract supplementation modulates T lymphocyte function in older women.

Ganoderma lucidum (a mushroom used in traditional Chinese medicine) compounds may attenuate ageing-related physiological changes and restore normal immunity. However, studies on the physiological effects of Ganoderma lucidum dry extract food supplements are few..

Immune supportMetabolic healthGut & microbiomeLiver support

Reishi · 2024 · Journal Article · Journal of ethnopharmacology

Ganoderma lucidum ethanol extracts ameliorate hepatic fibrosis and promote the communication between metabolites and gut microbiota g_Ruminococcus through the NF-κB and TGF-β1/Smads pathways.

ETHNOPHARMACOLOGICAL RELEVANCE: Ganoderma lucidum, a traditional edible medicinal mushroom, has been widely reported to improve liver diseases as a dietary intervention for people..

Immune supportSkin & hydration

Reishi · 2024 · Preprint · journal metadata

Ganoderma lucidum Extract Modulates Gene Expression Profiles Associated with Antioxidant Defense, Cytoprotection, and Senescence in Human Dermal Fibroblasts: A Transcriptomic Analysis

Cellular senescence plays a crucial role in skin aging, with senescent dermal fibroblasts contributing to reduced skin elasticity and increased inflammation. This study investigated the potential of Ganoderma lucidum (Reishi) extract to modulate the senescent phenotype of human dermal fibroblasts..

Reishi · 2024 · Journal Article · Food & function

Ganoderma lucidum methyl ganoderate E extends lifespan and modulates aging-related indicators in Caenorhabditis elegans.

Methyl Ganoderate E (MGE) is a triterpenoid derived from Ganoderma lucidum (Reishi), an edible mushroom, commonly processed into food forms such as soups, drinks, culinary dishes, and supplements. MGE has been shown to inhibit 3T3-L1 murine adipocyte differentiation when combined with other G.

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

Reishi · 2024 · Journal Article · International journal of biological macromolecules

Ganoderma lucidum polysaccharide promotes broiler health by regulating lipid metabolism, antioxidants, and intestinal microflora.

Ganoderma lucidum polysaccharides (GLP) are the primary bioactive macromolecular compounds of Ganoderma lucidum, possessing antioxidant and immunomodulatory effects. Hot water extract of Juncao-substrate Ganoderma Lucidum residue (HWE-JGLR) is abundant in GLP..

Immune supportGut & microbiomeLiver support

Reishi · 2024 · Research Article · Heliyon

Ganoderma lucidum polysaccharides reduce the severity of acute liver injury by improving the diversity and function of the gut microbiota.

Acute liver injury (ALI) is an abnormal liver function caused by oxidative stress, inflammation and other mechanisms.The interaction between intestine and liver plays an important role in ALI, and natural polysaccharides can participate in the regulation of ALI by regulating the composition of intestinal flora..

Immune supportCognition & nerves

Reishi · 2024 · Research Article · Frontiers in pharmacology

Ganoderma lucidum spore extract improves sleep disturbances in a rat model of sporadic Alzheimer's disease.

Introduction: Ganoderma lucidum (G. lucidum, Lingzhi) has long been listed as a premium tonic that can be used to improve restlessness, insomnia, and forgetfulness..

Almond Mushroom · 2024 · Journal Article · Journal of ethnopharmacology

GC/MS and 2D NMR-based approach to evaluate the chemical profile of hydroalcoholic extract from Agaricus blazei Murill and its anti-inflammatory effect on human neutrophils.

ETHNOPHARMACOLOGICAL RELEVANCE: Agaricus blazei Murill (AbM) is one of the main mushrooms used for medicinal purposes. The use of AbM in the preparation of teas is widespread mainly in Asian countries, while in Brazil it is used as a functional food to combat inflammatory diseases and cancer..

OncologyImmune support

Energy & fatigueMetabolic health

Cordyceps · 2024 · Research Article · Genes

Genomic and Transcriptome Analysis Reveals the Biosynthesis Network of Cordycepin in Cordyceps militaris.

Cordycepin is the primary active compound of Cordyceps militaris. However, the definitive genetic mechanism governing cordycepin synthesis in fruiting body growth and development remains elusive, necessitating further investigation.

OncologyImmune supportMetabolic healthGut & microbiome

Cordyceps · 2024 · Journal Article · Journal of ethnopharmacology

Genotoxicity, acute and sub-acute toxicity profiles of methanolic Cordyceps militaris (L.) Fr. extract in Swiss Albino Mice.

ETHNOPHARMACOLOGICAL RELEVANCE: Cordyceps militaris, a traditional medicinal fungus, parasitizes the intestines of lepidopteron pupae or larvae, predominantly during the winter, and undergoes fruiting in the summer or autumn. Compounds extracted from C..

King Oyster · 2024 · Journal Article · Chemistry & biodiversity

Green Synthesis of Pleurotus Eryngii-Derived Nanomaterials for Phytopathogen Control.

Growing concerns over the human health and environmental impacts of conventional fungicides, coupled with the escalating challenge of microbial resistance, have fueled the search for sustainable biocontrol strategies against plant pathogens..

Reishi · 2024 · Research Article · Gels (Basel, Switzerland)

Green Synthesis of ZnO Nanoparticles via Ganoderma Lucidum Extract: Structural and Functional Analysis in Polymer Composites.

Metallic nanoparticles are of growing interest due to their broad applications. This study presents the green synthesis of zinc oxide (ZnO) nanoparticles (ZnNPs) using Ganoderma Lucidum mushroom extract, characterized by DLS, SEM, XRD, and FTIR spectroscopy analyses..

Energy & fatigueMetabolic health

Cordyceps · 2024 · Journal Article · Gene

Holistic transcriptional responses of Cordyceps militaris to different culture temperatures.

Cordyceps militaris is a medicinal entomopathogenic fungus containing valuable biometabolites for pharmaceutical applications. Its genetic inheritance and environmental factors play a crucial role in the production of biomass enriched with cordycepin..

OncologyImmune supportGut & microbiome

Cordyceps · 2024 · Journal Article · International journal of medicinal mushrooms

Hot Water Extract of the Caterpillar Medicinal Mushroom Cordyceps militaris (Ascomycetes) Fruiting Body Activates Myeloid Dendritic Cells through A Dectin-1-Mediated Pathway.

The traditional use of Cordyceps militaris, an entomopathogenic fungus, in East Asian medicine has been well documented. Our previous study revealed that the fruiting body powder of C..

Lion's Mane · 2024 · Research Article · Molecules (Basel, Switzerland)

Identification and Reconstitution of the First Two Enzymatic Steps for the Biosynthesis of Bioactive Meroterpenoids from Hericium erinaceus (Lion's Mane Mushroom).

Hericium erinaceus (Lion's Mane mushroom) is widely consumed for its numerous reported benefits for brain health. A growing body of evidence suggests that these benefits are likely attributable to aromatic compounds contained in its fruiting bodies, including the meroterpenoids hericenones..

Cognition & nerves

Energy & fatigueGut & microbiomeSkin & hydration

King Oyster · 2024 · Research Article · Foods (Basel, Switzerland)

Identification of Peptides from Edible Pleurotus eryngii Mushroom Feet and the Effect of Delaying D-Galactose-Induced Senescence of PC12 Cells Through TLR4/NF-κB/MAPK Signaling Pathways.

Pleurotus eryngii mushroom has been proven to have anti-aging bioactivities. However, few studies have focused on edible Pleurotus eryngii mushroom feet peptides (PEMFPeps)..

Cordyceps · 2024 · Research Article · Insects

Immunomodulation and Protective Effects of Cordyceps militaris Extract Against Candida albicans Infection in Galleria mellonella Larvae.

Cordyceps militaris-derived formulations are currently used for multiple purposes because of their medical properties, especially immune system modulation. This study analyzes the inhibitory effects of C..

Immune supportMetabolic health

Cordyceps · 2024 · Research Article · Molecules (Basel, Switzerland)

Immunomodulatory Effect of Cordyceps militaris Polysaccharide on RAW 264.7 Macrophages by Regulating MAPK Signaling Pathways.

Polysaccharide is one of the principal bioactive components found in medicinal mushrooms and has been proven to enhance host immunity. However, the possible mechanism of immunomodulatory activity of Cordyceps militaris polysaccharide is not fully understood..

Cordyceps · 2024 · Journal Article · International journal of medicinal mushrooms

Impact of Cooking Methods on Sensory Evaluation and Nutritional Properties of Caterpillar Medicinal Mushroom Cordyceps militaris (Ascomycetes).

This study addresses the alterations in nutrients [calcium, iron, and vitamins C and E (VC and VE, respectively)] and cordycepin content, alongside its sensory appeal in Cordyceps militaris, subjected to five distinct cooking methods: boiling, steaming, roasting, microwaving, and deep-frying..

Chaga · 2024 · Research Article · Molecules (Basel, Switzerland)

Impact of Incorporating Dried Chaga Mushroom (Inonotus obliquus) into Gluten-Free Bread on Its Antioxidant and Sensory Characteristics.

Gluten-free bread is increasingly popular among individuals with celiac disease, and The incorporation of mushroom flour offers a novel method to enhance its nutritional profile, antioxidant content, and sensory properties..

Metabolic healthGut & microbiome

Shiitake · 2024 · Research Article · Foods (Basel, Switzerland)

Impact of Incorporating Shiitake Mushrooms (Lentinula edodes) on Microbial Community and Flavor Volatiles in Traditional Jiuqu.

Jiuqu is one of the important raw materials for brewing Chinese rice wine (Huangjiu), often known as the "bone of wine". In this study, the microbial community and flavor substances of Jiuqu made with different amounts of shiitake mushroom (Lentinula edodes) were investigated through high-throughput sequencing….

Cordyceps · 2024 · Research Article · Foods (Basel, Switzerland)

Improved Cordycepin Production by Cordyceps Militaris Using Corn Steep Liquor Hydrolysate as an Alternative Protein Nitrogen Source.

Cordycepin production in the submerged culture of Cordyceps militaris was demonstrated using hydrolyzed corn processing protein by-products, known as corn steep liquor hydrolysate (CSLH), as an alternative nitrogen source..

Immune supportMetabolic health

Cordyceps · 2024 · Journal Article · Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire

Improvement of extracellular polysaccharides production from Cordyceps militaris immobilized alginate beads in repeated-batch fermentation

Cordyceps militaris (C. militaris) is a unique medicinal fungus of the genus Cordyceps.

Reishi · 2024 · Research Article · Antibiotics (Basel, Switzerland)

In Vitro Antimicrobial Efficacy Assessment of Ethanolic, Aqueous, and Dual Solvent Extracts of Mushroom Ganoderma lucidum: Genomic and Morphological Analysis.

Background: Infectious diseases caused by bacteria are life-threating and are among the major causes of death in the world. Antibiotics have offered humans a new approach to infection control..

Immune supportMetabolic healthGut & microbiome

Yellow Morel · 2024 · Research Article · Food chemistry: X

In vitro digestion and fecal fermentation behaviors of exopolysaccharide from Morchella esculenta and its impacts on hypoglycemic activity via PI3K/Akt signaling and gut microbiota modulation.

This study aimed to evaluate the effects of gastrointestinal digestion on the physicochemical properties and hypoglycemic activity of extracellular polysaccharides from Morchella esculenta (MEPS)..

Immune supportMetabolic healthGut & microbiome

King Oyster · 2024 · Journal Article · Food & function

In vitro gastrointestinal digestion and fecal fermentation of Pleurotus eryngii proteins extracted using different methods: insights for the utilization of edible mushroom-based proteins as novel nutritional and functional components.

Pleurotus eryngii (P. eryngii) protein is considered a high-quality protein because it is rich in essential amino acids and displays multiple significant functional characterizations that vary with its fabrication processes.

Immune supportMetabolic healthGut & microbiome

Cordyceps · 2024 · Preprint · journal metadata

In vitro simulation of oral gastric intestinal digestion and fecal fermentation of Cordyceps militaris polysaccharides reveal its digestion profile and effect on the modulation of the gut microbiota

Abstract Background: Polysaccharides isolated from Cordyceps militaris mycelia (IPS) are natural polymer compounds composed of monosaccharides, structurally diverse and exhibit various metabolic and biological activities..