MycoData

The priority pathogen list of the World Health Organization classified Pseudomonas aeruginosa as the second top critical pathogen. Hence, the development of novel antibacterial strategies to tackle this bacterium is highly necessary..

Immune supportEnergy & fatigue

High relevance

Niu-Chang-Chih · 2022 · Research Article · Frontiers in molecular biosciences

Antrodia camphorata-Derived Antrodin C Inhibits Liver Fibrosis by Blocking TGF-Beta and PDGF Signaling Pathways.

Hepatic stellate cells (HSCs) play an essential role in the development of liver fibrosis. Antrodia camphorata (A.

Energy & fatigueLiver supportSkin & hydration

High relevance

Reishi · 2022 · Research Article · Molecules (Basel, Switzerland)

Autotoxicity of Endogenous Organic Acid Stress in Two Ganoderma lucidum Cultivars.

Ganoderma lucidum has been used as a rare medical mushroom for centuries in China, due to its health-promoting properties. Successive cropping obstacles are common in the cultivation of G.

Energy & fatigueMetabolic health

High relevance

Yellow Morel · 2022 · Journal Article · International journal of medicinal mushrooms

Bioactive Extract of Morel Mushroom, Morchella esculenta (Ascomycota) Attenuates Doxorubicin-Induced Oxidative Stress Leading to Myocardial Injury.

Doxorubicin (DOX) is an extensively used anticancer drug for chemotherapy. Cardiotoxicity induced by DOX is an impediment in its clinical use.

OncologyEnergy & fatigue

High relevance

Turkey Tail · 2022 · Journal Article · Water environment research: a research publication of the Water Environment Federation

Bioremediation of bisphenol A found in industrial wastewater using Trametes versicolor (TV) laccase nanoemulsion-based bead organogel in packed bed reactor.

Bisphenol A (BPA) is one of the toxic chemicals, which is widely used for manufacturing epoxy, polyester resin, and polycarbonates. These materials are extensively used in manufacturing of reusable bottles, baby bottles, dental sealants, various medical devices, and so forth..

Immune supportEnergy & fatigueMetabolic health

High relevance

Snow Fungus · 2022 · Research Article · Frontiers in nutrition

Chemical profile and antioxidant activity of bidirectional metabolites from Tremella fuciformis and Acanthopanax trifoliatus as assessed using response surface methodology.

This study aimed to establish a bidirectional fermentation system using Tremella fuciformis and Acanthopanax trifoliatus to promote the transformation and utilization of the synthesized antioxidant metabolites from fermentation supernatant..

Immune supportEnergy & fatigueSkin & hydration

High relevance

Shiitake · 2022 · Research Article · Frontiers in microbiology

Comparative structural analysis on the mitochondrial DNAs from various strains of Lentinula edodes.

The evolution of mitochondria through variations in mitochondrial DNA (mtDNA) is one of the intriguing questions in eukaryotic cells. In order to assess the causes of the variations in mitochondria, the mtDNAs of the 21 strains of Lentinula edodes were assembled for this study, and analyzed together with four….

Energy & fatigue

High relevance

Shiitake · 2022 · Research Article · Frontiers in microbiology

Comparative Transcriptome Analysis Provides Insights Into the Mechanism by Which 2,4-Dichlorophenoxyacetic Acid Improves Thermotolerance in Lentinula edodes.

As the widest cultivated edible mushroom worldwide, Lentinula edodes suffers serious yield and quality losses from heat stress during growth and development, and in our previous study, exogenous 2,4-Dichlorophenoxyacetic acid (2,4-D) was found to improve the thermotolerance of L..

Energy & fatigue

High relevance

Lion's Mane · 2022 · Journal Article · Carbohydrate polymers

Construction of hydrogels based on the homogeneous carboxymethylated chitin from Hericium erinaceus residue: Role of carboxymethylation degree

Carboxymethyl chitin hydrogels with different degree of substitution (DS) were prepared by the homogeneous carboxymethylation of chitin extracted from Hericium erinaceus residue. The effect of DS on gel structure and property were studied..

Energy & fatigue

High relevance

Oyster Mushroom · 2022 · Journal Article · Food Hydrocolloids

Correlating rheology with 3D printing performance based on thermo-responsive κ-carrageenan/Pleurotus ostreatus protein with regard to interaction mechanism

Accurate 3D printing of thermo-responsive gel inks is a great challenge as the sol-gel transition and rheological properties change during extrusion are not easy to precisely regulate with 3D printing behavior has not been sufficiently studied..

Energy & fatigue

High relevance

Reishi · 2022 · Journal Article · International journal of medicinal mushrooms

Cytotoxicity of Medicinal Mushrooms Oudemansiella canarii and Ganoderma lucidum (Agaricomycetes) Against Hematologic Malignant Cells via Activation of Apoptosis-Related Markers.

Cancer is the second leading cause of death worldwide, and despite of the of the availability of the advanced chemical treatments, development of effective and safe alternatives derived from natural resources are still of high interest..

OncologyEnergy & fatigue

High relevance

Chaga · 2022 · Research Article · Nutrients

Effect of Inonotus obliquus Extract Supplementation on Endurance Exercise and Energy-Consuming Processes through Lipid Transport in Mice.

Inonotus obliquus (IO) is used as functional food to treat diabetes. This study investigated the effect of IO supplementation on body composition in relation to changes in energy expenditure and exercise performance..

OncologyEnergy & fatigueMetabolic health

High relevance

Maitake · 2022 · Journal Article · Food research international (Ottawa, Ont.)

Effect of low-intensity magnetic field on the growth and metabolite of Grifola frondosa in submerged fermentation and its possible mechanisms

This study aimed to investigate the effects of low intensity alternating magnetic field on the submerged fermentation of Grifola frondosa, and its possible mechanism was also explored..

Immune supportEnergy & fatigue

High relevance

Snow Fungus · 2022 · Research Article · Ultrasonics sonochemistry

Effects of combined ultrasonic and microwave vacuum drying on drying characteristics and physicochemical properties of Tremella fuciformis.

This study analyzes the effects of ultrasonic waves on the drying kinetics of Tremella fuciformis during microwave vacuum drying. The physicochemical properties and structural characteristics of T..

Immune supportEnergy & fatigue

High relevance

Lion's Mane · 2022 · Journal Article · Animal feed science and technology

Effects of dietary Hericium erinaceus powder on growth, hematology, disease resistance, and expression of genes related immune response against thermal challenge of Nile tilapia (Oreochromis niloticus)

Functional feed additives have been promising possibilities for improving fish immune function. The present study attempts to investigate the effect of dietary Hericium erinaceus (HE) supplementation on growth performance, hematology, disease resistance, and expression of genes related immune response against thermal….

Immune supportEnergy & fatigue

High relevance

Cordyceps · 2022 · Journal Article · International journal of medicinal mushrooms

Efficacy of Aqueous Extract of Chinese Caterpillar Mushroom Ophiocordyceps sinensis (Ascomycota) Against Simulated Altitude Stress and Subacute Toxicity Studies.

Exposure to high altitude severely impacts performance of unacclimatized individuals and contraindications associated with synthetic drugs ascertain the need for development of herbal drugs..

Immune supportEnergy & fatigueMetabolic health

High relevance

Reishi · 2022 · Journal Article · Scientific reports

Ganoderma lucidum aqueous extract inducing PHGPx to inhibite membrane lipid hydroperoxides and regulate oxidative stress based on single-cell animal transcriptome.

In this study, the single-cell eukaryotic model organism Tetrahymena thermophila was used as an experimental material to reveal the anti-aging mechanism of Ganoderma lucidum aqueous extract. After treatment with the G.

Energy & fatigueMetabolic healthSkin & hydration

High relevance

Reishi · 2022 · Journal Article · Translational andrology and urology

Ganoderma lucidum polysaccharide ameliorated diabetes mellitus-induced erectile dysfunction in rats by regulating fibrosis and the NOS/ERK/JNK pathway.

BACKGROUND: Diabetes mellitus-induced erectile dysfunction (DMED) is a frequent complication of diabetes mellitus (DM), with limited therapy at present. This study aimed to explore the role and mechanism of Ganoderma lucidum polysaccharide (GLP) on DMED..

OncologyImmune supportCognition & nervesEnergy & fatigue

High relevance

Almond Mushroom · 2022 · Journal Article · Journal of ethnopharmacology

Gastroprotective effect of hydroalcoholic extract from Agaricus blazei Murill against ethanol-induced gastric ulcer in mice.

ETHNOPHARMACOLOGICAL RELEVANCE: The use of mushrooms in medicine is quite old and the first report about the use of genus Agaricus in treatment of ulcers occurred in Byzantine period..

Energy & fatigue

High relevance

Enoki · 2022 · Research Article · Mycobiology

Gene Expression Analyses of Mutant Flammulina velutipes (Enokitake Mushroom) with Clogging Phenomenon.

Regulation of proper gene expression is important for cellular and organismal survival, maintenance, and growth. Abnormal gene expression, even for a single critical gene, can thwart cellular integrity and normal physiology to cause diseases, aging, and death..

Energy & fatigue

High relevance

Maitake · 2022 · Research Article · Nutrients

Grifola frondosa Extract Containing Bioactive Components Blocks Skin Fibroblastic Inflammation and Cytotoxicity Caused by Endocrine Disrupting Chemical, Bisphenol A.

Grifola frondosa (GF), a species of Basidiomycotina, is widely distributed across Asia and has been used as an immunomodulatory, anti-bacterial, and anti-cancer agent..

OncologyImmune supportEnergy & fatigueSkin & hydration

High relevance

Maitake · 2022 · Research Article · Current research in food science

Grifolamine A, a novel bis-γ-butyrolactone from Grifola frondosa exerted inhibitory effect on α-glucosidase and their binding interaction: Affinity and molecular dynamics simulation.

A novel bis-γ-butyrolactone grifolamine A (1), the first γ-butyrolactone dimer from nature, together with three known γ-butyrolactones (2-4), was isolated from the byproduct from Grifola frondosa polysaccharides preparation process..

Immune supportEnergy & fatigue

High relevance

Oyster Mushroom · 2022 · Research Article · Animals: an open access journal from MDPI

Growth Performance and Hematological Changes in Growing Sika Deers Fed with Spent Mushroom Substrate of Pleurotus ostreatus.

The purpose of this experiment is to expand the feed of growing sika deer and to explore the effects on growing sika deer of the spent mushroom substrate of Pleurotus ostreatus (SMS-MP). Twelve immature female growing sika deer were randomly assigned to four groups..

Immune supportEnergy & fatigueGut & microbiome

High relevance

Reishi · 2022 · Research Article · International journal of molecular sciences

Heme Oxygenase/Carbon Monoxide Participates in the Regulation of Ganoderma lucidum Heat-Stress Response, Ganoderic Acid Biosynthesis, and Cell-Wall Integrity.

Carbon monoxide (CO), a product of organic oxidation processes, arises in vivo principally from the enzymatic reaction of heme oxygenase (HO, transcription gene named HMX1). HO/CO has been found to exert many salutary effects in multiple biological processes, including the stress response..

Energy & fatigue

High relevance

Shiitake · 2022 · Research Article · Journal of lasers in medical sciences

Introducing Protein Homeostasis and Glycogen Synthesis as Two Targets of Blue Light Radiation in Lentinula edodes.

Introduction: There are documents about the biological effects of blue light radiation on different organisms. An understanding of the molecular mechanism of radiation effects on biological samples is an important event which has attracted researchers' attention..

Energy & fatigue

High relevance

Yellow Morel · 2022 · Journal Article · Archives of microbiology

Investigation of Morchella esculenta and Morchella conica for their antibacterial potential against methicillin-susceptible Staphylococcus aureus, methicillin-resistant Staphylococcus aureus and Streptococcus pyogenes.

Antimicrobial resistance is an alarming problem, especially due to emergence of methicillin-resistance Staphylococcus aureus (MRSA). World Health Organization (WHO) has already listed MRSA as a top priority pathogen for the development of novel antibacterial agents..

Energy & fatigueGut & microbiome

High relevance

Oyster Mushroom · 2022 · Journal Article · Food research international (Ottawa, Ont.)

Lipidomic profiling of Pleurotus ostreatus by LC/MS Q-TOF analysis.

In this paper, for the first time a lipidomic analysis on Pleurotus ostreatus species was performed by liquid chromatography quadrupole time-of-flight mass spectrometry (LC/MS Q-TOF). Twenty-seven lipid classes, including polar and non-polar lipid classes, were detected..

Cognition & nervesEnergy & fatigue

High relevance

Shiitake · 2022 · Research Article · Mycobiology

Mitochondrial Effects on the Physiological Characteristics of Lentinula edodes.

In the mating of filamentous basidiomycetes, dikaryotic mycelia are generated through the reciprocal movement of nuclei to a monokaryotic cytoplasm where a nucleus of compatible mating type resides, resulting in the establishment of two different dikaryotic strains having the same nuclei but different mitochondria..

Energy & fatigue

High relevance

Oyster Mushroom · 2022 · Research Article · Microbial cell factories

Mnsod1 promotes the development of Pleurotus ostreatus and enhances the tolerance of mycelia to heat stress.

BACKGROUND: Superoxide dismutases (SODs, EC 1.15.1.1) are defense proteins that can be used as sweepers to clear reactive oxygen species (ROS). They have been widely studied in the plant.

Energy & fatigue

High relevance

Yellow Morel · 2022 · Research Article · AMB Express

Morchella esculenta polysaccharide attenuate obesity, inflammation and modulate gut microbiota.

Edible mushrooms have now been suggested as promising sources of biological functional ingredients and are the subject of the most recent nutrition research and novel functional foods. Polysaccharides from mushrooms exhibit impressive biological effects, notably against obesity..

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

High relevance

Lion's Mane · 2022 · Journal Article · Journal of agricultural and food chemistry

Natural Compound 2-Chloro-1,3-dimethoxy-5-methylbenzene, Isolated from Hericium Erinaceus, Inhibits Fungal Growth by Disrupting Membranes and Triggering Apoptosis.

In this study, 2-chloro-1,3-dimethoxy-5-methylbenzene (CDM), a natural product with anti-Candida albicans activity, was discovered from the Hericium erinaceus mycelium. The minimum inhibitory concentration of CDM was 62.5 μg/mL..

OncologyEnergy & fatigue

High relevance

Oyster Mushroom · 2022 · Research Article · Journal of fungi (Basel, Switzerland)

Nitric Oxide Negatively Regulates the Rapid Formation of Pleurotus ostreatus Primordia by Inhibiting the Mitochondrial aco Gene.

Nitric oxide (NO) is as a signaling molecule that participates in the regulation of plant development and in a number of physiological processes. However, the function and regulatory pathway of NO in the growth and development of edible mushrooms are still unknown..

Energy & fatigueRespiratory

High relevance

Yellow Morel · 2022 · Research Article · Foods (Basel, Switzerland)

Nutrition Profile and Animal-Tested Safety of Morchella esculenta Mycelia Produced by Fermentation in Bioreactors.

Morchella esculenta (ME), or "true" morel mushrooms, are one of the most expensive mushrooms. M.

OncologyImmune supportEnergy & fatigueMetabolic health

High relevance

Enoki · 2022 · Journal Article · Industrial crops and products

Optimization of ultrasonic extraction of polysaccharides from Flammulina velutipes residue and its protective effect against heavy metal toxicity

The extraction process of polysaccharides from Flammulina velutipes residue (FVRP) was optimized by the single factor test and response surface methodology with the physical and chemical properties of FVRP determined..

Immune supportEnergy & fatigueMetabolic health

High relevance

Reishi · 2022 · Journal Article · Food & function

Polysaccharide from Ganoderma lucidum alleviates cognitive impairment in a mouse model of chronic cerebral hypoperfusion by regulating CD4+CD25+Foxp3+ regulatory T cells.

Ganoderma lucidum (G. lucidum) is a kind of edible and medicinal mushroom.

Immune supportCognition & nervesEnergy & fatigue

High relevance

Maitake · 2022 · Journal Article · Journal of the science of food and agriculture

Purification and characterization of Se-enriched Grifola frondosa glycoprotein, and evaluating its amelioration effect on As3+ -induced immune toxicity.

BACKGROUND: Selenium (Se)-enriched glycoproteins have been a research highlight for the role of both Se and glycoproteins in immunoregulation. Arsenic (As) is a toxicant that is potentially toxic to the immune function and consequently to human health..

Immune supportEnergy & fatigue

High relevance

Maitake · 2022 · Journal Article · Journal of the science of food and agriculture

Purification and characterization of Se‐enriched Grifola frondosa glycoprotein, and evaluating its amelioration effect on As3+‐induced immune toxicity

BACKGROUND: Selenium (Se)‐enriched glycoproteins have been a research highlight for the role of both Se and glycoproteins in immunoregulation. Arsenic (As) is a toxicant that is potentially toxic to the immune function and consequently to human health..

Immune supportEnergy & fatigue

High relevance

Reishi · 2022 · Journal Article · Molecular biology reports

Regulation of Nrf2 and Nrf2-related proteins by ganoderma lucidum ın hepatocellular carcinoma.

BACKGROUND: HCC is among the most common cancer. Ganoderma lucidum (G.lucidum) has been essential in preventing and treating cancer.

OncologyEnergy & fatigueLiver support

High relevance

Oyster Mushroom · 2022 · Research Article · Antioxidants (Basel, Switzerland)

Salicylic Acid Enhances Heat Stress Resistance of Pleurotus ostreatus (Jacq.) P. Kumm through Metabolic Rearrangement.

Pleurotus ostreatus (Jacq.) P. Kumm is cultivated worldwide, and its growth is seriously threatened by heat stress.

Energy & fatigueMetabolic health

High relevance

Lion's Mane · 2022 · Research Article · Nutrients

Searching for a Longevity Food, We Bump into Hericium erinaceus Primordium Rich in Ergothioneine: The "Longevity Vitamin" Improves Locomotor Performances during Aging.

Phenotypic frailty is characterized by a progressive decline in physical functioning. During ageing, morphological and functional alterations involve the brain, and chief theories involve oxidative stress, free radical accumulation, and reduced antioxidant defenses as the most implicated mechanisms..

Immune supportCognition & nervesEnergy & fatigueSkin & hydration

High relevance

Reishi · 2022 · Journal Article · Applied and environmental microbiology

Spermidine Regulates Mitochondrial Function by Enhancing eIF5A Hypusination and Contributes to Reactive Oxygen Species Production and Ganoderic Acid Biosynthesis in Ganoderma lucidum.

Spermidine, a kind of polycation and one important member of the polyamine family, is essential for survival in many kinds of organisms and participates in the regulation of cell growth and metabolism..

Energy & fatigue

High relevance

Reishi · 2022 · Research Article · Frontiers in pharmacology

Sporoderm-Broken Spores of Ganoderma lucidum Sensitizes Ovarian Cancer to Cisplatin by ROS/ERK Signaling and Attenuates Chemotherapy-Related Toxicity.

Although platinum-based chemotherapeutics such as cisplatin are the cornerstone of treatment for ovarian cancer, their clinical application is profoundly limited due to chemoresistance and severe adverse effects. Sporoderm-broken spores of Ganoderma lucidum (SBSGL) have been reported to possess antitumor effects..

OncologyEnergy & fatigueGut & microbiome

High relevance

Mesima · 2022 · Research Article · Antioxidants (Basel, Switzerland)

Styrylpyrones from Phellinus linteus Mycelia Alleviate Non-Alcoholic Fatty Liver by Modulating Lipid and Glucose Metabolic Homeostasis in High-Fat and High-Fructose Diet-Fed Mice.

Phellinus linteus (PL), an edible and medicinal mushroom containing a diversity of styrylpyrone-type polyphenols, has been shown to have a broad spectrum of bioactivities. In this study, the submerged liquid culture in a 1600-L working volume of fermentor was used for the large-scale production of PL mycelia..

Energy & fatigueMetabolic healthLiver support

High relevance

Mesima · 2022 · Journal Article · Molecular biology reports

Systematic evaluation of the anti-tumor effect of Phellinus linteus polysaccharide in thyroid carcinoma in vitro.

BACKGROUND: Thyroid carcinoma (TC) is the most common malignant tumor of the endocrine system. Phellinus linteus polysaccharide (PLP) physiologically acts as a suitable anti-tumor molecule..

OncologyImmune supportEnergy & fatigueRespiratory

High relevance

Maitake · 2022 · Research Article · Mitochondrial DNA. Part B, Resources

The complete mitochondrial genome of the edible mushroom Grifola frondosa.

The culinary-medicinal mushroom Grifola frondosa is widely cultivated in East Asia. In this study, the complete mitochondrial genome of G.

Energy & fatigue

High relevance

Reishi · 2022 · Research Article · Journal of fungi (Basel, Switzerland)

The Effect of Mitochondria on Ganoderma lucidum Growth and Bioactive Components Based on Transcriptomics.

Mitochondria are the power source of living cells and implicated in the oxidative metabolism. However, the effect of mitochondria on breeding is usually ignored in conventional research..

Immune supportEnergy & fatigueGut & microbiome

High relevance

Reishi · 2022 · Research Article · Nutrients

Triterpenoids and Polysaccharides from Ganoderma lucidum Improve the Histomorphology and Function of Testes in Middle-Aged Male Mice by Alleviating Oxidative Stress and Cellular Apoptosis.

Aging is an inevitable physiological process accompanied by a decline in body physiology, including male fertility. A preparation from Ganoderma lucidum (GL) containing triterpenes and polysaccharides has been shown to have anti-aging properties..

OncologyImmune supportEnergy & fatigueSkin & hydration

High relevance

Cordyceps · 2022 · Preprint · journal metadata

Tumor suppression by Chinese cordyceps extract via anti-angiogenesis

Development of pharmacological agents for anti-angiogenesis to disrupt the vascular supply and starve tumor of nutrients and oxygen is a novel strategy for tumor therapy. Chinese cordyceps ( Ophiocordyceps sinensis ), a traditional Chinese herb, has been widely reported to exhibit antitumor effects..

OncologyImmune supportEnergy & fatigue

High relevance

Reishi · 2022 · Research Article · RSC advances

ZnO and Ag NP-decorated ZnO nanoflowers: green synthesis using Ganoderma lucidum aqueous extract and characterization.

Fungi produce and excrete various proteins, enzymes, polysaccharides, and secondary metabolites, which may be used as media for the "green" synthesis of metal and semiconductor nanoparticles (NPs)..

Immune supportEnergy & fatigue

High relevance

Lion's Mane · 2021 · Journal Article · Journal of food biochemistry

A novel polysaccharide from Hericium erinaceus: Preparation, structural characteristics, thermal stabilities, and antioxidant activities in vitro

A novel polysaccharide fraction (HEP) from Hericium erinaceus was successively isolated and purified in the present study. We researched its structure and thermal stabilities, and further studied its antioxidant activities in vitro..

Immune supportEnergy & fatigueMetabolic health