MycoData

Reishi · 2022 · Research Article · Frontiers in nutrition

Extraction, Structural Characterization, and Immunomodulatory Activity of a High Molecular Weight Polysaccharide From Ganoderma lucidum.

Ganoderma lucidum polysaccharides (GLP) exhibited excellent immunomodulatory activity. Unfortunately, the structure and immunomodulatory activity of GLP are still unclear..

Immune supportMetabolic healthLiver support

Enoki · 2022 · Research Article · Nutrients

Flammulina velutipes Mycorrhizae Attenuate High Fat Diet-Induced Lipid Disorder, Oxidative Stress and Inflammation in the Liver and Perirenal Adipose Tissue of Mice.

Flammulina velutipes (FV) is edible mushroom that has nutritional and medicinal values. FV mycorrhizae, the by-products of FV, are an abundant source and receive less attention..

Metabolic healthGut & microbiome

Oyster Mushroom · 2022 · Randomized Controlled Trial · European journal of nutrition

Fortifying a meal with oyster mushroom powder beneficially affects postprandial glucagon-like peptide-1, non-esterified free fatty acids and hunger sensation in adults with impaired glucose tolerance: a double-blind randomized controlled crossover trial.

PURPOSE: Impaired glucose tolerance (IGT) is a pathophysiological condition characterized by insulin resistance with known metabolic consequences such as postprandial hyperglycemia and hypertriglyceridemia..

Immune supportMetabolic healthGut & microbiomeLiver support

Reishi · 2022 · Journal Article · Food & function

Ganoderic acid A from Ganoderma lucidum protects against alcoholic liver injury through ameliorating the lipid metabolism and modulating the intestinal microbial composition.

Alcoholic liver injury is mainly caused by long-term excessive alcohol consumption and has become a global public threat to human health. It is well known that Ganoderma lucidum has excellent beneficial effects on liver function and lipid metabolism..

Immune supportMetabolic healthGut & microbiomeLiver support

Reishi · 2022 · Journal Article · Current research in food science

Ganoderic acids-rich ethanol extract from Ganoderma lucidum protects against alcoholic liver injury and modulates intestinal microbiota in mice with excessive alcohol intake.

Alcoholic liver injury is mainly caused by excessive alcohol consumption and has become a global public health problem threatening human health. It is well known that Ganoderma lucidum possesses various excellent beneficial effects on liver function and lipid metabolism..

Energy & fatigueMetabolic healthSkin & hydration

Reishi · 2022 · Journal Article · Scientific reports

Ganoderma lucidum aqueous extract inducing PHGPx to inhibite membrane lipid hydroperoxides and regulate oxidative stress based on single-cell animal transcriptome.

In this study, the single-cell eukaryotic model organism Tetrahymena thermophila was used as an experimental material to reveal the anti-aging mechanism of Ganoderma lucidum aqueous extract. After treatment with the G.

OncologyImmune supportMetabolic health

Chaga · 2022 · Research Article · BMC genomics

Genome sequencing of Inonotus obliquus reveals insights into candidate genes involved in secondary metabolite biosynthesis.

BACKGROUND: Inonotus obliquus is an important edible and medicinal mushroom that was shown to have many pharmacological activities in preclinical trials, including anti-inflammatory, antitumor, immunomodulatory, and antioxidant effects..

Reishi · 2022 · Research Article · Frontiers in microbiology

Gllac7 Is Induced by Agricultural and Forestry Residues and Exhibits Allelic Expression Bias in Ganoderma lucidum.

Ganoderma lucidum has a wide carbon spectrum, while the expression profile of key genes relevant to carbon metabolism on different carbon sources has been seldom studied. Here, the transcriptomes of G.

Immune supportCognition & nervesMetabolic healthGut & microbiome

Lion's Mane · 2022 · Research Article · Journal of animal science and technology

Gut microbiota profiling in aged dogs after feeding pet food contained Hericium erinaceus.

Health concern of dogs is the most important issue for pet owners. People who have companied the dogs long-term provide the utmost cares for their well-being and healthy life.

Metabolic healthGut & microbiome

Oyster Mushroom · 2022 · Research Article · Animals: an open access journal from MDPI

Hematological Changes in Sika Doe and Suckling Fawn Fed with Spent Mushroom Substrate of Pleurotus ostreatus.

Sika deer velvet antler is the most important animal nutraceutic in traditional Chinese medicine. Reducing the breeding cost of sika deer by looking for a low-cost diet is the main research direction at present..

Immune supportMetabolic healthLiver support

Reishi · 2022 · Research Article · Metabolites

Hypouricemic Effect of Submerged Culture of Ganoderma lucidum in Potassium Oxonate-Induced Hyperuricemic Rats.

Hyperuricemia is a disease caused by a high level of uric acid in the blood. It is an important factor for gout and may be linked to renal and hepatic failure.

Reishi · 2022 · Research Article · Frontiers in microbiology

Identification of a Novel Metabolic Target for Bioactive Triterpenoids Biosynthesis in Ganoderma lucidum.

Triterpenoids are crucial active ingredients of Ganoderma lucidum (G. lucidum) with various health benefits.

Maitake · 2022 · Research Article · Food science & nutrition

Immunostimulatory and antioxidant activities of the selenized polysaccharide from edible Grifola frondosa.

Grifola frondosa polysaccharide (GFP2) was extracted and purified by anion-exchange chromatography. A selenized G.

OncologyImmune supportMetabolic healthGut & microbiome

Mesima · 2022 · Research Article · Pharmaceuticals (Basel, Switzerland)

Immunostimulatory Effect of Postbiotics Prepared from Phellinus linteus Mycelial Submerged Culture via Activation of Spleen and Peyer's Patch in C3H/HeN Mice.

Medicinal mushrooms are an important natural resource promoting health benefits. Herein, Phellinus linteus mycelia were prepared under submerged cultivation, the mycelium-containing culture broth was extracted as a whole to obtain the postbiotic materials (PLME), and its effect on the immune system was evaluated in….

Reishi · 2022 · Research Article · Molecules (Basel, Switzerland)

Inhibition on α-Glucosidase Activity and Non-Enzymatic Glycation by an Anti-Oxidative Proteoglycan from Ganoderma lucidum.

The prevention of postprandial hyperglycemia and diabetic complications is crucial for diabetes management. Inhibition of α-glucosidase to slow carbohydrate metabolism is a strategy to alleviate postprandial hyperglycemia..

Metabolic healthLiver support

Chaga · 2022 · Journal Article · European journal of pharmacology

Inonotus obliquus and its bioactive compounds alleviate non-alcoholic fatty liver disease via regulating FXR/SHP/SREBP-1c axis.

Non-alcoholic fatty liver disease (NAFLD) is currently the most common chronic liver disease worldwide. However, there is still lack of specific drugs for treating NAFLD in clinic..

Reishi · 2022 · Research Article · Journal of fungi (Basel, Switzerland)

Integrated Transcriptomics and Nontargeted Metabolomics Analysis Reveal Key Metabolic Pathways in Ganoderma lucidum in Response to Ethylene.

Ganoderic acid (GA) is an important secondary metabolite of Ganoderma lucidum with a diverse array of pharmacological properties. In this study, we found that exogenous ethylene increased the production of endogenous ethylene and ganoderic acid in G.

Oyster Mushroom · 2022 · Journal Article · Environmental pollution (Barking, Essex: 1987)

Integration of transcriptomic and proteomic reveals the toxicological molecular mechanisms of decabromodiphenyl ethane (DBDPE) on Pleurotus ostreatus.

Decabromodiphenyl ethane (DBDPE), as one of the most widely used new brominated flame retardants (NBFRs), can pose a potential threat to human health and the environment. An integrated transcriptome and proteome was performed for investigating the toxicological molecular mechanisms of Pleurotus ostreatus (P..

Immune supportMetabolic healthGut & microbiome

Snow Fungus · 2022 · Journal Article · Food Hydrocolloids

Interaction between potato starch and Tremella fuciformis polysaccharide

In order to elucidate the mechanism of interaction between Tremella fuciformis polysaccharide (TP) and potato starch (PS), PS-TP composites with different concentrations of TP were prepared, and their physicochemical properties, in vitro digestibility characteristic and microstructure were investigated..

OncologyImmune supportMetabolic healthGut & microbiome

Shiitake · 2022 · Journal Article · Arquivos de gastroenterologia

LENTINULA EDODES POLYSACCHARIDES SUPPRESSED PRO-INFLAMMATORY CYTOKINES EXPRESSION AND COLITIS IN MICE.

BACKGROUND: Polysaccharides from edible mushrooms possess immunomodulatory, anti-inflammatory, and anti-tumor activities. Recent studies indicated that necroptosis plays a role in the pathogenesis of inflammatory diseases and mediates increased expression of inflammatory cytokines..

Shiitake · 2022 · Research Article · Antioxidants (Basel, Switzerland)

Lentinula edodes, a Novel Source of Polysaccharides with Antioxidant Power.

The fruiting bodies of edible mushrooms represent an important source of biologically active polysaccharides. In this study, Lentinula edodes crude polysaccharides (LECP) were extracted in hot water, and their antioxidant and antiradical activities were investigated..

Cordyceps · 2022 · Research Article · Frontiers in microbiology

Medium optimization for high mycelial soluble protein content of Ophiocordyceps sinensis using response surface methodology.

Ophiocordyceps sinensis is widely utilized due to its pharmaceutical value. Mycelial protein forms a key active component of O.

Reishi · 2022 · Journal Article · International journal of biological macromolecules

Microwave-assisted degradation of β-D-glucan from Ganoderma lucidum and the structural and immunoregulatory properties of oligosaccharide fractions.

Microwave-assisted degradation of β-(1 → 3,1 → 6)-D-glucan from Ganoderma lucidum and correlated immunoregulatory activities were investigated in this study. The optimal temperature and degradation time for microwave hydrothermal hydrolysis were 140 °C and 40 min, respectively..

Snow Fungus · 2022 · Journal Article · Food research international (Ottawa, Ont.)

Moisture and caking resistant Tremella fuciformis polysaccharides microcapsules with hypoglycemic activity

Tremella fuciformis polysaccharides (TPs) have attracted extensive attention as functional food constituents due to their bioactivity. However, β-D-glucan obtained from TPs is readily degraded by oxidation and easy to absorb water and agglomerate..

OncologyImmune supportMetabolic healthGut & microbiome

Yellow Morel · 2022 · Research Article · Frontiers in nutrition

Morchella esculenta mushroom polysaccharide attenuates diabetes and modulates intestinal permeability and gut microbiota in a type 2 diabetic mice model.

Type 2 diabetes mellitus (T2DM) is a health issue that causes serious worldwide economic problems. It has previously been reported that natural polysaccharides have been studied with regard to regulating the gut microbiota, which plays an important role in T2DM..

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

Yellow Morel · 2022 · Research Article · AMB Express

Morchella esculenta polysaccharide attenuate obesity, inflammation and modulate gut microbiota.

Edible mushrooms have now been suggested as promising sources of biological functional ingredients and are the subject of the most recent nutrition research and novel functional foods. Polysaccharides from mushrooms exhibit impressive biological effects, notably against obesity..

OncologyImmune supportMetabolic healthLiver support

Yellow Morel · 2022 · Journal Article · Food research international (Ottawa, Ont.)

Mycochemical profile and health-promoting effects of morel mushroom Morchella esculenta (L.) – A review

Mushrooms have been well known for centuries in traditional Chinese medicine for their medicinal properties. Morchella esculenta (L.) Pers.

Reishi · 2022 · Journal Article · Microbiological research

NAD+-dependent Glsirt1 has a key role on secondary metabolism in Ganoderma lucidum.

Nicotinamide adenine dinucleotide (NAD+) is an important intracellular metabolite that is involved in different cel1lular processes. Glnmnat is the key enzyme that can affect intracellular NAD+ content..

OncologyImmune supportEnergy & fatigueMetabolic health

Yellow Morel · 2022 · Research Article · Foods (Basel, Switzerland)

Nutrition Profile and Animal-Tested Safety of Morchella esculenta Mycelia Produced by Fermentation in Bioreactors.

Morchella esculenta (ME), or "true" morel mushrooms, are one of the most expensive mushrooms. M.

Oyster Mushroom · 2022 · Research Article · Bioresources and bioprocessing

Nutritional and antioxidant changes in lentils and quinoa through fungal solid-state fermentation with Pleurotus ostreatus.

Solid-state fermentation (SSF) may be a suitable bioprocess to produce protein-vegetal ingredients with increased nutritional and functional value. This study assessed changes in phenol content, antinutrient content, biomass production and protein production resulting from the metabolic activity of Pleurotus….

Immune supportEnergy & fatigueMetabolic health

Enoki · 2022 · Journal Article · Industrial crops and products

Optimization of ultrasonic extraction of polysaccharides from Flammulina velutipes residue and its protective effect against heavy metal toxicity

The extraction process of polysaccharides from Flammulina velutipes residue (FVRP) was optimized by the single factor test and response surface methodology with the physical and chemical properties of FVRP determined..

Immune supportMetabolic healthGut & microbiomeLiver support

Reishi · 2022 · Journal Article · International journal of biological macromolecules

Organic chromium derived from the chelation of Ganoderma lucidum polysaccharide and chromium (III) alleviates metabolic syndromes and intestinal microbiota dysbiosis induced by high-fat and high-fructose diet.

Organic chromium is of great interest and has become an important chromium supplement resource in recent years because of its low toxicity and easy absorption. In our previous study, we synthesized a novel organic chromium [GLP-Cr] through the chelation of Ganoderma lucidum polysaccharide and chromium (III)..

Immune supportMetabolic healthGut & microbiomeLiver support

Oyster Mushroom · 2022 · Research Article · Nutrients

Pleurotus Ostreatus Ameliorates Obesity by Modulating the Gut Microbiota in Obese Mice Induced by High-Fat Diet.

Pleurotus ostreatus (PO), a common edible mushroom, contains rich nutritional components with medicinal properties. To explore the effect of PO on ameliorating obesity and modulating the gut microbiota, we administered the mice with a low-fat diet or high-fat diet containing different dosages of PO (mass fraction: 0%,….

Immune supportMetabolic healthLiver support

Maitake · 2022 · Journal Article · The Journal of pharmacy and pharmacology

Polysaccharides of Grifola frondosa ameliorate oxidative stress and hypercholesterolaemia in hamsters fed a high-fat, high-cholesterol diet.

OBJECTIVES: This study was to evaluate the antioxidant and anti-hypercholesterolaemia activities of Grifola frondosa in hamsters fed a high-fat, high-cholesterol (HFHC) diet. METHODS: G..

Oyster Mushroom · 2022 · Research Article · Journal of fungi (Basel, Switzerland)

Responses of the Mushroom Pleurotus ostreatus under Different CO2 Concentration by Comparative Proteomic Analyses.

BACKGROUND: Pleurotus ostreatus is a popular edible mushroom in East Asian markets. Research on the responses of P.

Energy & fatigueMetabolic health

Oyster Mushroom · 2022 · Research Article · Antioxidants (Basel, Switzerland)

Salicylic Acid Enhances Heat Stress Resistance of Pleurotus ostreatus (Jacq.) P. Kumm through Metabolic Rearrangement.

Pleurotus ostreatus (Jacq.) P. Kumm is cultivated worldwide, and its growth is seriously threatened by heat stress.

Niu-Chang-Chih · 2022 · Research Article · Frontiers in microbiology

Structural and Potential Functional Properties of Alkali-Extracted Dietary Fiber From Antrodia camphorata.

Antrodia camphorata is rich in a variety of bioactive ingredients; however, the utilization efficiency of the residue of A. camphorata is low, resulting in serious waste.

Snow Fungus · 2022 · Research Article · Journal of fungi (Basel, Switzerland)

Study of Dimorphism Transition Mechanism of Tremella fuciformis Based on Comparative Proteomics.

Tremella fuciformis is a dimorphic fungus that can undertake a reversible transition between yeast-like conidia and hyphal forms. The transformation mechanism and proteomic differences between these two forms have not been reported..

Energy & fatigueMetabolic healthLiver support

Mesima · 2022 · Research Article · Antioxidants (Basel, Switzerland)

Styrylpyrones from Phellinus linteus Mycelia Alleviate Non-Alcoholic Fatty Liver by Modulating Lipid and Glucose Metabolic Homeostasis in High-Fat and High-Fructose Diet-Fed Mice.

Phellinus linteus (PL), an edible and medicinal mushroom containing a diversity of styrylpyrone-type polyphenols, has been shown to have a broad spectrum of bioactivities. In this study, the submerged liquid culture in a 1600-L working volume of fermentor was used for the large-scale production of PL mycelia..

OncologyImmune supportMetabolic health

Lion's Mane · 2022 · Research Article · Current research in toxicology

Subchronic toxicity and genotoxicity studies of Hericium erinaceus β-glucan extract preparation.

The medicinal effects of Hericium erinaceus have been long documented in scientific studies of Eastern traditional medicine. It is widely consumed, because of its nutritional qualities and perceived health benefits.

Reishi · 2022 · Journal Article · Microbiology spectrum

Target of Rapamycin Mediated Ornithine Decarboxylase Antizyme Modulate Intracellular Putrescine and Ganoderic Acid Content in Ganoderma lucidum.

Putrescine (Put) has been shown to play an important regulatory role in cell growth in organisms. As the primary center regulating the homeostasis of polyamine (PA) content, ornithine decarboxylase antizyme (AZ) can regulate PA content through feedback..

Metabolic healthGut & microbiomeLiver support

Reishi · 2022 · Research Article · Foods (Basel, Switzerland)

The Protective Effects of Ganoderic Acids from Ganoderma lucidum Fruiting Body on Alcoholic Liver Injury and Intestinal Microflora Disturbance in Mice with Excessive Alcohol Intake.

This study aimed to investigate the protective effects of ganoderic acids (GA) from Ganoderma lucidum against liver injury and intestinal microbial disorder in mice with excessive alcohol intake..

Enoki · 2022 · Journal Article · Journal of the science of food and agriculture

The structure-activity mechanism of the changes in the physicochemical properties of Flammulina velutipes polysaccharides during ultrasonic extraction.

BACKGROUND: The high yield of ultrasonic extraction has been widely studied. However, the effects of ultrasound on the properties of products has generally been ignored..

Immune supportCognition & nervesMetabolic healthGut & microbiome

Snow Fungus · 2022 · Research Article · Frontiers in microbiology

Tremella fuciformis polysaccharide reduces obesity in high-fat diet-fed mice by modulation of gut microbiota.

Obesity is a metabolic disease associated with gut microbiota and low-grade chronic inflammation. Tremella fuciformis is a medicinal and edible fungus; polysaccharide (TP) is the main active component, which has a variety of biological activities, such as hypoglycemic and hypolipidemic..

OncologyImmune supportCognition & nervesMetabolic health

Snow Fungus · 2022 · Research Article · Frontiers in pharmacology

Tremella fuciformis polysaccharides alleviate induced atopic dermatitis in mice by regulating immune response and gut microbiota.

Atopic dermatitis (AD), characterized by severe pruritus, immune imbalance, and skin barrier dysfunction, has a high incidence worldwide. Recent evidence has shown that the modulation of gut microbiota is crucial for alleviating clinical symptoms of AD..

Shiitake · 2022 · Journal Article · Food Research International

Understanding the promotion of heat treatment on the flavor of Lentinula edodes using metabolomics integrated with transcriptomics

The transcriptome and metabolome analyses revealed the differentially expressed metabolites (DEMs) and genes (DEGs) in the dried Lentinula edodes' response to heat treatment..

Immune supportEnergy & fatigueMetabolic health

Lion's Mane · 2021 · Journal Article · Journal of food biochemistry

A novel polysaccharide from Hericium erinaceus: Preparation, structural characteristics, thermal stabilities, and antioxidant activities in vitro

A novel polysaccharide fraction (HEP) from Hericium erinaceus was successively isolated and purified in the present study. We researched its structure and thermal stabilities, and further studied its antioxidant activities in vitro..

OncologyImmune supportMetabolic health

Oyster Mushroom · 2021 · Journal Article · International journal of biological macromolecules

A water-soluble selenium-enriched polysaccharide produced by Pleurotus ostreatus: Purification, characterization, antioxidant and antitumor activities in vitro.

The development and application of new selenium-enriched polysaccharides has become a critical topic in recent years. In this study, a natural selenium-enriched polysaccharide fraction (Se-POP-21) produced by Pleurotus ostreatus was purified, characterized, and investigated the antioxidant and antitumor activities in….