MycoData

Flammulina velutipes (F. velutipes) residues polysaccharide (FVRP) is a high molecular weight polysaccharide with diverse bioactivities extracted from F.

Immune supportGut & microbiome

High relevance

Lion's Mane · 2024 · Journal Article · Food Hydrocolloids

Physicochemical properties of polysaccharides from Hericium erinaceus by steam explosion pretreatment and its effects on human gut microbiota

Crude polysaccharides (HEP) extracted from Hericium erinaceus (H. erinaceus) using hot water soaking were focused in this study.

Immune supportGut & microbiome

High relevance

Oyster Mushroom · 2024 · Journal Article · Environmental pollution (Barking, Essex: 1987)

Pleurotus ostreatus polysaccharide-mediated modulation of skin damage caused by microcystin-LR in tadpoles.

In this study, we aimed to evaluate the effect of dietary supplementation with edible mushroom (Pleurotus ostreatus)-derived polysaccharides on microcystin leucine-arginine (MC-LR)-induced skin damage in Pelophylax nigromaculatus tadpoles..

OncologyImmune supportGut & microbiomeSkin & hydration

High relevance

Lion's Mane · 2024 · Research Article · Poultry science

Polysaccharide from Hericium erinaceus improved laying performance of aged hens by promoting yolk precursor synthesis and follicle development via liver-blood-ovary axis.

Little information is available on the effect of Hericium erinaceus polysaccharides (HEP) on laying hens, especially on improving liver and ovarian health and function..

Immune supportEnergy & fatigueMetabolic healthLiver support

High relevance

Reishi · 2024 · Journal Article · Carbohydrate polymers

Polysaccharide structure evaluation of Ganoderma lucidum from different regions in China based on an innovative extraction strategy

The polysaccharides and triterpenes are important functional components of Ganoderma lucidum, but traditional preparation process of G. lucidum functional components can only realize the preparation of single functional component, which has poor targeting and low efficiency..

Immune support

High relevance

Reishi · 2024 · Journal Article · Carbohydrate polymers

Polysaccharide structure evaluation of Ganoderma lucidum from different regions in China based on an innovative extraction strategy.

Immune support

High relevance

Maitake · 2024 · Journal Article · International journal of biological macromolecules

Polysaccharide with anticancer activity from Grifola frondosa cultured in industrial wastewater of Agaricus bisporus.

Culture conditions for Grifola frondosa using Agaricus bisporus industrial wastewater as a medium were optimized using Plackett-Burman and Box-Behnken methodologies. Plackett-Burman screening identified culture temperature, shaking speed, and wastewater solubility as the key factors influencing G.

OncologyImmune supportMetabolic healthLiver support

High relevance

Reishi · 2024 · Journal Article · International journal of biological macromolecules

Polysaccharides extraction from Ganoderma lucidum using a ternary deep eutectic solvents of choline chloride/guaiacol/lactic acid.

In this study, a purposefully formulated ternary deep eutectic solvents (DESs), consisting of choline chloride, guaiacol, and lactic acid in a molar ratio of 1:1:1, was synthesized for the extraction of polysaccharides from Ganoderma lucidum..

Immune supportEnergy & fatigueMetabolic health

High relevance

Lion's Mane · 2024 · Journal Article · International journal of biological macromolecules

Polysaccharides from an edible mushroom, Hericium erinaceus, alleviate ulcerative colitis in mice by inhibiting the NLRP3 inflammasomes and reestablish intestinal homeostasis.

This study aimed to assess the effects of polysaccharides extracted from Hericium erinaceus fruiting bodies (HEFPs) on the inflammatory response to oxidative stress in a mouse model of ulcerative colitis (UC) induced by ingestion of dextran sodium sulfate..

Immune supportGut & microbiome

High relevance

Lion's Mane · 2024 · Journal Article · International journal of biological macromolecules

Polysaccharides from Hericium erinaceus and its immunomodulatory effects on RAW 264.7 macrophages.

This study aimed to optimize the extraction of Hericium erinaceus polysaccharides (HEP) using ultrasound-assisted enzymatic extraction combined with Plackett-Burman design (PBD) and response surface methodology (RSM)..

Immune support

High relevance

Mesima · 2024 · Journal Article · International journal of biological macromolecules

Polysaccharides from Phellinus linteus attenuate type 2 diabetes mellitus in rats via modulation of gut microbiota and bile acid metabolism.

Type 2 diabetes mellitus (T2DM) is the most prevalent metabolic disorder. Polysaccharides from Phellinus linteus (PLP) have been found to have anti-diabetes effects, but the mechanism has not been elucidated..

Immune supportMetabolic healthGut & microbiomeLiver support

High relevance

Turkey Tail · 2024 · Research Article · Microorganisms

Polysaccharides from Trametes versicolor as a Potential Prebiotic to Improve the Gut Microbiota in High-Fat Diet Mice.

Polysaccharides derived from Trametes versicolor have been found to exhibit hypolipidemic activity in hyperlipidemic mice, but the mechanism by which they modulate intestinal flora is still unclear..

Immune supportMetabolic healthGut & microbiomeLiver support

High relevance

Oyster Mushroom · 2024 · Journal Article · International journal of biological macromolecules

Preparation, physicochemical and biological evaluation of chitosan Pleurotus ostreatus polysaccharides active films for food packaging.

The aim of this study was to create CS-POP composite films by blending Pleurotus ostreatus stalk polysaccharides (POP) and chitosan (CS). The effects of adding different concentrations (0 %, 0.25 %, 0.5 %, 0.75 %, and 1 %) of POP on the mechanical, barrier, and optical properties of the CS films were investigated..

Immune support

High relevance

Oyster Mushroom · 2024 · Journal Article · Food Research International

Preparation, structural characterization and neuroprotective effects to against H2O2-induced oxidative damage in PC12 cells of polysaccharides from Pleurotus Ostreatus

Pleurotus ostreatus is one of the most common edible and medicinal fungi in life, and its polysaccharide has been a hot research topic in recent years. In this paper, a new intracellular polysaccharide component named P.

OncologyImmune supportCognition & nervesMetabolic health

High relevance

Snow Fungus · 2024 · Journal Article · International journal of biological macromolecules

Pressure-controlled steam explosion as pretreatment for efficient extraction of Tremella fuciformis polysaccharide: Structure and bioactivity.

Tremella fuciformis (TF) is a mushroom with rich nutritional and medicinal value. This study aimed to develop an efficient extraction technique for TF polysaccharide (TFP) to enhance its health benefits..

Immune supportMetabolic healthSkin & hydration

High relevance

Reishi · 2024 · Research Article · BMC complementary medicine and therapies

Protective effect of Ganoderma lucidum-fermented crop extracts against hydrogen peroxide- or β-amyloid-induced damage in human neuronal SH-SY5Y cells.

BACKGROUND: Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the accumulation of stacked β-amyloid peptides in the brain and associated with the generation of oxidative stress. So far, there is no cure for AD or a way to stop its progression..

Immune supportCognition & nervesEnergy & fatigue

High relevance

Chaga · 2024 · Research Article · Heliyon

Protective effect of Inonotus obliquus polysaccharide on MGO-induced nonenzymatic glycation fibroblasts.

BACKGROUND: The nonenzymatic glycation of fibroblasts causes functional downregulation and behavioral disorders in the skin. METHODS: To investigate the effect of Inonotus obliquus on the nonenzymatic glycation of skin, we examined the inhibition of advanced glycation end products (AGEs) using four extraction methods:….

Immune supportEnergy & fatigueMetabolic healthSkin & hydration

High relevance

Chaga · 2024 · Journal Article · International journal of biological macromolecules

Protective effect of Inonotus obliquus polysaccharide on mice infected with Neospora caninum.

The study aimed to explore the protective effects of Inonotus obliquus polysaccharide (IOP) on Neospora caninum (N. caninum) infection.

OncologyImmune supportCognition & nervesLiver support

High relevance

Reishi · 2024 · Research Article · Frontiers in pharmacology

Protective effects of Ganoderma lucidum spores on estradiol benzoate-induced TEC apoptosis and compromised double-positive thymocyte development.

Backgroud: Thymic atrophy marks the onset of immune aging, precipitating developmental anomalies in T cells. Numerous clinical and preclinical investigations have underscored the regulatory role of Ganoderma lucidum spores (GLS) in T cell development..

OncologyImmune support

High relevance

Zhu Ling · 2024 · Journal Article · Phytochemical analysis: PCA

Rapid screening, isolation, and activity evaluation of potential xanthine oxidase inhibitors in Polyporus umbellatus and mechanism of action in the treatment of gout.

INTRODUCTION: Studies show that Polyporus umbellatus has some pharmacological effects in enhancing immunity and against gout. OBJECTIVES: We aimed to establish new techniques for extraction, biological activity screening, and preparation of xanthine oxidase inhibitors (XODIs) from P.

Immune support

High relevance

Enoki · 2024 · Research Article · International journal of molecular sciences

Renoprotective Effects of Brown-Strain Flammulina velutipes Singer in Chronic Kidney Disease-Induced Mice Through Modulation of Oxidative Stress and Inflammation and Regulation of Renal Transporters.

Cisplatin, widely used in chemotherapy, acts through mechanisms such as oxidative stress to damage the DNA and cause the apoptosis of cancer cells. Although effective, cisplatin treatment is associated with considerable side effects including chronic kidney disease (CKD)..

OncologyImmune supportEnergy & fatigue

High relevance

Lion's Mane · 2024 · Journal Article · Carbohydrate polymers

Resveratrol-loaded sulfated Hericium erinaceus β-glucan-chitosan nanoparticles: Preparation, characterization and synergistic anti-inflammatory effects

Resveratrol (RES) is a natural polyphenol with excellent biological activity. But the poor stability and bioavailability of RES severely limit its application.

Immune supportGut & microbiome

High relevance

Lion's Mane · 2024 · Journal Article · Carbohydrate polymers

Resveratrol-loaded sulfated Hericium erinaceus β-glucan-chitosan nanoparticles: Preparation, characterization and synergistic anti-inflammatory effects.

Resveratrol (RES) is a natural polyphenol with excellent biological activity. But the poor stability and bioavailability of RES severely limit its application.

Immune supportGut & microbiome

High relevance

Reishi · 2024 · Journal Article · International journal of biological macromolecules

Roles of α-1,3-glucosyltransferase in growth and polysaccharides biosynthesis of Ganoderma lucidum.

Ganoderma lucidum polysaccharides are valuable natural compounds possessing significant biological activity, with glycosyltransferases playing a crucial role in their biosynthesis..

Immune supportEnergy & fatigueMetabolic health

High relevance

Chaga · 2024 · Research Article · Microorganisms

Selection and Genetic Analysis of High Polysaccharide-Producing Mutants in Inonotus obliquus.

Inonotus obliquus, a medicinal fungus, has garnered significant attention in scientific research and medical applications. In this study, protoplasts of the I.

Immune support

High relevance

Maitake · 2024 · Journal Article · International journal of biological macromolecules

Selective impact of three homogenous polysaccharides with different structural characteristics from Grifola frondosa on human gut microbial composition and the structure-activity relationship.

Natural polysaccharides interact with gut microbes to enhance human well-being. Grifola frondosa is a polysaccharides-rich edible and medicinal mushroom.

Immune supportGut & microbiome

High relevance

Maitake · 2024 · Journal Article · International journal of biological macromolecules

Selenochemical modification of low molecular weight polysaccharides from Grifola frondosa and the mechanism of their inhibitory effects on gastric cancer cells.

An important micronutrient involved in immune response and antitumor is selenium. LMW-GFP, a polysaccharide extracted from Grifola frondosa seed bodies, has a relatively weak antitumor effect on BGC-823 and MFC cells in vitro, whereas selenium binding to LMW-GFP can significantly increase the in vitro antitumor….

OncologyImmune supportEnergy & fatigue

High relevance

Shiitake · 2024 · Research Article · International journal of molecular sciences

Selenopolysaccharide Isolated from Lentinula edodes Mycelium Affects Human T-Cell Function.

Lentinula edodes polysaccharides are natural immunomodulators. SeLe30, analyzed in this study, is a new mixture of selenium-enriched linear 1,4-α-glucans and 1,3-β- and 1,6-β-glucans isolated from L.

Immune supportCognition & nerves

High relevance

Enoki · 2024 · Research Article · Foods (Basel, Switzerland)

Steam Explosion-Assisted Extraction of Ergosterol and Polysaccharides from Flammulina velutipes (Golden Needle Mushroom) Root Waste.

In this work, steam explosion (SE) was applied to prompt the rapid extraction of ergosterol and polysaccharides from Flammulina velutipes root (FVR) waste. Ultrasound-assisted saponification extraction (UASE) followed by water extraction was used to prepare ergosterol and polysaccharides..

Immune supportMetabolic health

High relevance

Lion's Mane · 2024 · Research Article · Foods (Basel, Switzerland)

Structural Analysis and Antioxidant Activity of Alkaline-Extracted Glucans from Hericium erinaceus.

An alkali-soluble β-glucan (AHEP-A-b, 20 kDa) purified from Hericium erinaceus fruiting bodies, was structurally characterized and examined for antioxidant activity..

Immune support

High relevance

Chaga · 2024 · Journal Article · International journal of biological macromolecules

Structural analysis of polysaccharide from Inonotus obliquus and investigate combined impact on the sex hormones, intestinal microbiota and metabolism in SPF male mice.

The dysregulation of sex hormone levels is associated with metabolic disorders such as obesity. Inonotus obliquus polysaccharide (IOP) exhibits a promising therapeutic effect on conditions like obesity and diabetes, potentially linked to its influence on intestinal microbiota and metabolism..

Immune supportMetabolic healthGut & microbiome

High relevance

Reishi · 2024 · Journal Article · International journal of biological macromolecules

Structural characterization and anti-oxidative activity for a glycopeptide from Ganoderma lucidum fruiting body.

A water-soluble glycopeptide (named GL-PWQ3) with a molecular weight (Mw) of 2.40 × 104 g/mol was isolated from Ganoderma lucidum fruiting body by hot water extraction, membrane ultrafiltration, and gel column chromatography, which mainly consisted of glucose and galactose..

Immune supportMetabolic health

High relevance

Reishi · 2024 · Journal Article · Carbohydrate polymers

Structural characterization of a galactoglucomannan with anti-neuroinflammatory activity from Ganoderma lucidum

According to traditional Chinese medicine theory, Ganoderma lucidum (G. lucidum) presents certain effects for nourishing nerves and calming the mind.

Immune supportCognition & nerves

High relevance

Reishi · 2024 · Journal Article · Carbohydrate polymers

Structural characterization of a galactoglucomannan with anti-neuroinflammatory activity from Ganoderma lucidum.

According to traditional Chinese medicine theory, Ganoderma lucidum (G. lucidum) presents certain effects for nourishing nerves and calming the mind.

Immune supportCognition & nerves

High relevance

Snow Fungus · 2024 · Journal Article · Journal of the science of food and agriculture

Structural characterization of a novel polysaccharide from Tremella fuciformis and its interaction with gut microbiota

BACKGROUND: Because of their diverse biological activities, polysaccharides derived from Tremella fuciformis have received growing attention. This study aimed to investigate the structural characterization of a purified polysaccharide (designated as PTP‐3a) derived from T..

Immune supportMetabolic healthGut & microbiome

High relevance

Snow Fungus · 2024 · Journal Article · Journal of the science of food and agriculture

Structural characterization of a novel polysaccharide from Tremella fuciformis and its interaction with gut microbiota.

Immune supportMetabolic healthGut & microbiome

High relevance

Chaga · 2024 · Journal Article · International journal of biological macromolecules

Structural characterization of the polysaccharide from the black crystal region of Inonotus obliquus and its effect on AsPC-1 and SW1990 pancreatic cancer cell apoptosis.

In this study, one water soluble polysaccharide (IOP1-1) with a weight average molecular weight of 6886 Da was obtained from the black crystal region of Inonotus obliquus by hot water extraction, DEAE-52 cellulose extraction and Sephadex-100 column chromatography purification..

OncologyImmune supportEnergy & fatigue

High relevance

Enoki · 2024 · Research Article · Ultrasonics sonochemistry

Structural characterization, antioxidant activity, and fermentation characteristics of Flammulina velutipes residue polysaccharide degraded by ultrasonic assisted H2O2-Vc technique.

Adhere to the concept of low-carbon environmental protection and turning waste into treasure, polysaccharides from Flammulina velutipes residue polysaccharide (FVRP) has been developed and possesses diverse bioactivities, comprising antioxidant, hypoglycemic, and relieving heavy metal damage, which still has the….

Immune supportMetabolic healthGut & microbiome

High relevance

Enoki · 2024 · Research Article · Polymers

Structural Elucidation of a Polysaccharide from Flammulina velutipes and Its Lipid-Lowering and Immunomodulation Activities.

FVPT1, a novel heteropolysaccharide, was purified from the fruiting body of Flammulina velutipes using magnetic-field-assisted three-phase partitioning and gel permeation chromatography..

Immune supportMetabolic health

High relevance

Snow Fungus · 2024 · Journal Article · Journal of the science of food and agriculture

Structure and characterization of Tremella fuciformis polysaccharides/whey protein isolate nanoparticles for sustained release of curcumin.

BACKGROUND: Whey protein isolate (WPI) nanoparticles can be used in a strategy to improve the bioavailability of curcumin (CUR) although they are generally not stable. Previous studies have indicated that Tremella fuciformis polysaccharides (TFPs) can increase the stability of WPI..

Immune supportLiver support

High relevance

Enoki · 2024 · Journal Article · Food & function

Structure and immunostimulatory activity studies on two novel Flammulina velutipes polysaccharides: revealing potential impacts of →6)-α-D-Glcp(1→ on the TLR-4/MyD88/NF-κB pathway.

Two novel Flammulina velutipes (F. velutipes) polysaccharides, FVPH1 and FVPH2, were isolated and purified after hot water extraction.

Immune support

High relevance

Chaga · 2024 · Research Article · Food science & nutrition

Study of active components and mechanisms mediating the hypolipidemic effect of Inonotus obliquus polysaccharides.

Hyperlipidemia is a multifaceted metabolic disease, which is the major risk factor for atherosclerosis and cardiovascular diseases. Traditional Chinese medicine provides valuable therapeutic strategies in the treatment of hyperlipidemia..

Immune supportMetabolic healthLiver support

High relevance

Snow Fungus · 2024 · Research Article · Foods (Basel, Switzerland)

Study on the Optimization, Extraction Kinetics and Thermodynamics of the Ultrasound-Assisted Enzymatic Extraction of Tremella fuciformis Polysaccharides.

In this study, Tremella fuciformis polysaccharides (TFPs) were extracted by ultrasound-assisted enzymatic extraction (UAE) at different extraction parameters in order to explore the potential of ultrasound in intensifying the extraction yield..

Immune support

High relevance

Enoki · 2024 · Journal Article · International journal of biological macromolecules

Study on the physicochemical properties and antioxidant activities of Flammulina velutipes polysaccharide under controllable ultrasonic degradation based on artificial neural network.

The polysaccharide fraction (FVP2) with molecular weight of 1525.09 kDa and intrinsic viscosity of 3.43 dL/g was isolated and purified from Flammulina velutipes (F..

Immune supportSkin & hydration

High relevance

Maitake · 2024 · Journal Article · International journal of biological macromolecules

Synthesis and characterization of selenium nanoparticles stabilized by Grifola frondosa polysaccharides and gallic acid conjugates.

Selenium nanoparticles (SeNPs) are of interest for their versatility and low toxicity, but bare SeNPs are unstable and tend to aggregate and precipitate as black elemental Se, which limits the application of SeNPs..

OncologyImmune support

High relevance

Reishi · 2024 · Journal Article · International journal of biological macromolecules

Synthesis, characterization and MAFLD prevention potential of Ganoderma lucidum spore polysaccharide-stabilized selenium nanoparticles.

The unstability of selenium nanoparticles (SeNPs) results in decreased activity which limits its therapeutic potential. In this study, we utilized Ganoderma lucidum spore polysaccharide (GLP, Mw = 983.96 kDa) as a novel stabilizer to synthesize GLP-SeNPs..

Immune supportMetabolic health

High relevance

Reishi · 2024 · Journal Article · Carbohydrate polymers

Targeting TGFβ receptor-mediated snail and twist: WSG, a polysaccharide from Ganoderma lucidum, and it-based dissolvable microneedle patch suppress melanoma cells

Cutaneous melanoma is a lethal skin cancer variant with pronounced aggressiveness and metastatic potential. However, few targeted medications inhibit the progression of melanoma.

OncologyImmune supportLiver supportSkin & hydration

High relevance

Reishi · 2024 · Journal Article · Carbohydrate polymers

Targeting TGFβ receptor-mediated snail and twist: WSG, a polysaccharide from Ganoderma lucidum, and it-based dissolvable microneedle patch suppress melanoma cells.

Cutaneous melanoma is a lethal skin cancer variant with pronounced aggressiveness and metastatic potential. However, few targeted medications inhibit the progression of melanoma.

OncologyImmune supportLiver supportSkin & hydration

High relevance

Oyster Mushroom · 2024 · Research Article · Scientific reports

Tea and Pleurotus ostreatus intercropping modulates structure of soil and root microbial communities.

Intercropping with Pleurotus ostreatus has been demonstrated to increase the tea yield and alleviate soil acidification in tea gardens. However, the underlying mechanisms remain elusive..

Immune supportGut & microbiome

High relevance

Oyster Mushroom · 2024 · Research Article · Mycology

Textile residue-based mycelium biocomposites from Pleurotus ostreatus.

The research on mycelium-based biocomposites is increasing exponentially, due to their ability to be produced from renewable and sustainable substrates. In this sense, the present investigation explores the ability of Pleurotus ostreatus to grow on textile residues and form mycelium-based biocomposites..

Immune support