MycoData

Immune supportCognition & nervesEnergy & fatigueMetabolic health

Lion's Mane · 2020 · Review · Antioxidants (Basel, Switzerland)

Potential Antidepressant Effects of Scutellaria baicalensis, Hericium erinaceus and Rhodiola rosea.

Recent studies focused on the pharmacology and feasibility of herbal compounds as a potential strategy to target a variety of human diseases ranging from metabolic to brain disorders..

OncologyImmune supportCognition & nervesMetabolic health

Mesima · 2019 · Review · Molecules (Basel, Switzerland)

A Review: The Bioactivities and Pharmacological Applications of Phellinus linteus.

Phellinus linteus is a popular medicinal mushroom that is widely used in China, Korea, Japan, and other Asian countries. P.

OncologyImmune supportCognition & nervesMetabolic health

Niu-Chang-Chih · 2019 · Review · Applied microbiology and biotechnology

Diversity of potentially exploitable pharmacological activities of the highly prized edible medicinal fungus Antrodia camphorata.

Antrodia camphorata, also known as A. cinnamomea, is a precious medicinal basidiomycete fungus endemic to Taiwan.

OncologyImmune supportCognition & nervesMetabolic health

Snow Fungus · 2019 · Review · International journal of biological macromolecules

Structure, bioactivities and applications of the polysaccharides from Tremella fuciformis mushroom: A review.

Tremella fuciformis is an important edible mushroom that has been widely cultivated and used as food and medicinal ingredient in traditional Chinese medicine. In the past decades, many researchers have reported that T..

OncologyImmune supportEnergy & fatigueMetabolic health

Chaga · 2019 · Review · Phytotherapy research: PTR

The pharmacological potential and possible molecular mechanisms of action of Inonotus obliquus from preclinical studies.

The use of mushrooms as functional foods and in the treatment of diseases has a long history. Inonotus obliquus is a mushroom belonging to the Hymenochaetaceae family and has possible anticancer, antiviral, and hypoglycemic properties..

OncologyImmune supportMetabolic healthRespiratory

Maitake · 2018 · Review · Discovery medicine

Grifola frondosa polysaccharide: a review of antitumor and other biological activity studies in China.

Grifola frondosa, a species of Basidiomycotina, is an edible medicinal mushroom with a large fruiting body characterized by overlapping caps. The β-glucan is the major biologically active component in G.

Zhu Ling · 2017 · Review · Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

[Correlative analysis advance of chemical constituents of Polyporus umbellatus and Armillaria mellea].

Medicinal Polyporus umbellatus is the dry sclerotia of P. umbellatus, with the effect of diuresis; Armillaria mellea is a parasitic fungus which can infect plants up to 300 genera, with sedative, anticonvulsant and some other biological activities.

OncologyImmune supportMetabolic healthLiver support

Almond Mushroom · 2017 · Review · Current pharmaceutical design

Agaricus blazei Bioactive Compounds and their Effects on Human Health: Benefits and Controversies.

BACKGROUND: The mushroom Agaricus blazei has evoked considerable scientific and practical interest in several fields, especially those linked to its medicinal properties. This review aims to summarize and evaluate the past decade findings related to nutritional and therapeutic uses of A..

OncologyImmune supportMetabolic healthLiver support

Maitake · 2017 · Review · International journal of biological macromolecules

Polysaccharides in Grifola frondosa mushroom and their health promoting properties: A review.

Grifola frondosa (Dicks.) Gray is a widely consumed edible and medicinal fungus, Ancient books record that it can boost qi and fortify the spleen, moisten the lung and protect the liver. Modern people mainly use it to assist in the treatment of diabetes mellitus and various cancers.

Immune supportCognition & nervesMetabolic healthGut & microbiome

Cordyceps · 2026 · Review · Journal of inflammation research

Anti-Inflammatory Mechanisms and Translational Relevance of Cordyceps sinensis and Its Bioactive Constituents.

Cordyceps sinensis, an important medicinal fungus in traditional Chinese medicine, has gained increasing attention for its diverse pharmacological activities, particularly its anti-inflammatory properties..

Nameko · 2026 · Review · RSC advances

Extraction, purification, structural characterization, bioactivities, and applications of Pholiota nameko polysaccharide: a review.

Pholiota nameko, an edible mushroom, is recognized for its significant medicinal properties and broad application potential. Pholiota nameko polysaccharide (PNP), a major bioactive component derived from this fungus, exhibits diverse biological activities, including anti-inflammatory, antioxidant, antitumor,….

Immune supportMetabolic health

Nameko · 2025 · Review · Food science and biotechnology

Extraction, structure and bioactivities of polysaccharides from Pholiota nameko: a review.

Pholiota nameko, a famous edible mushroom, has broad application prospects in the field of health food development because of its high nutritional value, complex structure, and diverse biological activities..

Almond Mushroom · 2020 · Research Article · Food science & nutrition

Enhancement of glucose homeostasis through the PI3K/Akt signaling pathway by dietary with Agaricus blazei Murrill in STZ-induced diabetic rats.

Agaricus blazei Murrill (ABM) is an edible fungus. This study investigated the protective role of ABM fruiting body against streptozotocin (STZ)-induced diabetic rats.

Immune supportMetabolic health

Chaga · 2024 · Research Article · Journal of fungi (Basel, Switzerland)

The Effect of Green Extraction Technologies on the Chemical Composition of Medicinal Chaga Mushroom Extracts.

The mushroom industry should implement green extraction technologies; however, there is not enough information on the differences between these techniques expressed as the chemical composition of the resulting extract..

Immune supportEnergy & fatigueMetabolic health

Oyster Mushroom · 2024 · Research Article · Poultry science

The influence of dietary supplementation with oyster mushroom waste on laying hens' performance, egg quality and immune parameters.

The objective of the present study was to evaluate the effects of dietary supplementation with oyster mushroom (Pleurotus ostreatus) waste (OMW) on performance, egg quality, fatty acid (FA) profile and oxidative stability, serum and yolk cholesterol and immune parameters of laying hens..

Energy & fatigueMetabolic healthGut & microbiome

Cordyceps · 2023 · Randomized Controlled Trial, Veterinary · Archives of Razi Institute

Effect of Adding Cordyceps sinensis Extract and Probiotic to the Diet on Productive Performance of Broiler.

Following a substantial increase in poultry breeding, the demand for their meat has risen. Poultry meat is one of the primary sources of protein in human nutrition, which contributes to food security..

OncologyEnergy & fatigueMetabolic healthLiver support

Cordyceps · 2020 · Research Support, Non U.S. Gov'T · Integrative cancer therapies

Efficacy of Ethyl Acetate Fraction of Cordyceps militaris for Cancer-Related Fatigue in Blood Biochemical and 1H-Nuclear Magnetic Resonance Metabolomic Analyses.

This study investigated the adjuvant effects for anticancer and antifatigue of the combination of Cordyceps militaris extract with sorafenib. The 5 extracts of C militaris were obtained through hexane, chloroform, ethyl acetate, butanol, and water and were evaluated for anticancer growth activity..

Shiitake · 2020 · Research Support, Non U.S. Gov'T · PloS one

Mycelial biomass estimation and metabolic quotient of Lentinula edodes using species-specific qPCR.

Lentinula edodes, commonly known as shiitake, is an edible mushroom that is cultivated and consumed around the globe, especially in Asia. Monitoring mycelial growth inside a woody substrate is difficult, but it is essential for effective management of mushroom cultivation..

Energy & fatigueMetabolic health

Cordyceps · 2020 · Research Support, Non U.S. Gov'T · Cells

Probing Carbon Utilization of Cordyceps militaris by Sugar Transportome and Protein Structural Analysis.

Beyond comparative genomics, we identified 85 sugar transporter genes in Cordyceps militaris, clustering into nine subfamilies as sequence- and phylogenetic-based functional classification, presuming the versatile capability of the fungal growths on a range of sugars..

Immune supportCognition & nervesMetabolic health

Cordyceps · 2020 · Abstract · Current developments in nutrition

The Antidepressive and Anxiolytic Effects of Formula Consisted of Poria cocos and Cordyceps militaris Waster Medium Extract in Unpredictable Chronic Mild Stress Animal Model

Abstract Objectives According to the WHO report, depression will be the first of the global burden of diseases in 2030. There is more than fifty % of people suffered from depression and anxiety..

Almond Mushroom · 2020 · Research Support, Non U.S. Gov'T · Journal of food biochemistry

The beneficial effects of Agaricus blazei Murrill on hepatic antioxidant enzymes and the pancreatic tissue recovery in streptozotocin-induced diabetic rats.

Agaricus blazei Murrill (ABM), is a medicinal mushroom, has beneficial effects on diabetes mellitus. In this study, ABM extracts (ethanol extract, EE and ethyl acetate extract, EA) were evaluated to explore the beneficial effect on hepatic antioxidant activity and recovery of the pancreatic tissue in….

Oyster Mushroom · 2019 · Comparative Study · International journal of molecular sciences

Comparative Proteomic Analysis of Pleurotus ostreatus Reveals Great Metabolic Differences in the Cap and Stipe Development and the Potential Role of Ca2+ in the Primordium Differentiation.

Pleurotus ostreatus is a widely cultivated edible fungus around the world. At present, studies on the developmental process of the fruiting body are limited.

Cordyceps · 2019 · Comparative Study · Journal of bioscience and bioengineering

Enhanced exopolysaccharide production by Cordyceps militaris using repeated batch cultivation.

Cordyceps militaris exo-polysaccharides (EPS) have been reported to possess many benefits, such as anti-tumor, anti-inflammatory and antioxidant activities. In this study, the production of EPS via cultivation in a bioreactor was investigated..

OncologyImmune supportCognition & nervesMetabolic health

Reishi · 2019 · Research Support, Non U.S. Gov'T · Progress in molecular biology and translational science

Ganoderma lucidum polysaccharide used for treating physical frailty in China.

Ganoderma lucidum is an edible medicinal mushroom known as "Lingzhi" in China and "Reishi or Manetake" in Japan. It is a highly prized vitality-enhancing herb for >2000 years.

Immune supportMetabolic healthSkin & hydration

Wood Ear · 2019 · Evaluation Study · International journal of medicinal mushrooms

Hypoglycemic Effect of the Degraded Polysaccharides from the Wood Ear Medicinal Mushroom Auricularia auricula-judae (Agaricomycetes).

Auricularia auricula-judae is an important culinary-medicinal mushroom. The A.

Metabolic healthSkin & hydration

Cordyceps · 2019 · Research Support, Non U.S. Gov'T · Biomolecules

Improved Cordycepin Production by Cordyceps militaris KYL05 Using Casein Hydrolysate in Submerged Conditions.

Cordycepin, a beneficial bioactive product specifically found in Cordyceps, has received attention in various bioindustrial applications such as in pharmaceuticals, functional foods, and cosmetics, due to its significant functions. However, low productivity of cordycepin is a barrier to commercialization..

Cordyceps · 2019 · Comparative Study · MicrobiologyOpen

Metabolic comparison of aerial and submerged mycelia formed in the liquid surface culture of Cordyceps militaris.

An entomopathogenic fungus, Cordyceps sp. has been known to produce cordycepin which is a purine nucleoside antimetabolite and antibiotic with potential anticancer, antioxidant and anti-inflammatory activities..

Immune supportMetabolic health

Yellow Morel · 2019 · Research Support, Non U.S. Gov'T · Journal of food biochemistry

Polysaccharides production from soybean curd residue via Morchella esculenta.

To minimize the serious environmental pollution caused by food byproducts, soybean curd residue was used as the substrate to ferment polysaccharides by Morchella esculenta..

Shiitake · 2018 · Research Support, Non U.S. Gov'T · Biotechnology progress

Extraction of bioactive compounds against cardiovascular diseases from Lentinula edodes using a sequential extraction method.

Three extraction methods were sequentially combined to obtain fractions from Lentinula edodes (shiitake mushrooms) containing bioactive compounds against cardiovascular diseases (CVDs)..

Immune supportMetabolic healthGut & microbiome

King Oyster · 2018 · Research Support, Non U.S. Gov'T · Proteomics

Impacts of Dietary Pleurotus eryngii Polysaccharide on Nutrient Digestion, Metabolism, and Immune Response of the Small Intestine and Colon-An iTRAQ-Based Proteomic Analysis.

Pleurotus eryngii polysaccharides have been shown to exert significant biological activities to the host. However, few studies have been conducted on its effects on gastrointestinal tract (GIT) health alteration..

Immune supportMetabolic healthLiver support

King Oyster · 2018 · Research Support, Non U.S. Gov'T · Scientific reports

The characteristic, antioxidative and multiple organ protective of acidic-extractable mycelium polysaccharides by Pleurotus eryngii var. tuoliensis on high-fat emulsion induced-hypertriglyceridemic mice.

The antioxidant and multiple organ protection effects of acid- extracted mycelia polysaccharides (Ac-MPS) from Pleurotus eryngii var. tuoliensis on HFE-induced hypertriglyceridemic mice were investigated..

Cordyceps · 2018 · Research Support, Non U.S. Gov'T · Scientific reports

Uncovering global metabolic response to cordycepin production in Cordyceps militaris through transcriptome and genome-scale network-driven analysis.

The cellular metabolic adaptations of Cordyceps militaris have been progressively studied. In particular, the cordycepin pathway is of interest in medicinal applications..

OncologyImmune supportMetabolic healthLiver support

King Oyster · 2016 · Research Support, Non U.S. Gov'T · Carbohydrate polymers

Chemical characterization of Pleurotus eryngii polysaccharide and its tumor-inhibitory effects against human hepatoblastoma HepG-2 cells.

This study was designed to investigate the chemical characterization and antitumor effects of Pleurotus eryngii polysaccharides (PEP). The crude PEP was fractionated into two fractions, namely PEP-1 and PEP-2..

Cordyceps · 2016 · Research Support, Non U.S. Gov'T · Food & function

Cordyceps militaris fruit body extract ameliorates membranous glomerulonephritis by attenuating oxidative stress and renal inflammation via the NF-κB pathway.

Membranous glomerulonephritis (MGN) is a common pathogenesis of nephritic syndrome in adult patients. Nuclear factor kappa B (NF-κB) serves as the main transcription factor for the inflammatory response mediated nephropathy..

King Oyster · 2016 · Research Support, Non U.S. Gov'T · Preparative biochemistry & biotechnology

Production of versatile peroxidase from Pleurotus eryngii by solid-state fermentation using agricultural residues and evaluation of its catalytic properties.

Interest in production of ligninolytic enzymes has been growing over recent years for their use in various applications such as recalcitrant pollutants bioremediation; specifically, versatile peroxidase (VP) presents a great potential due to its catalytic versatility..

King Oyster · 2016 · Research Support, Non U.S. Gov'T · Genetics and molecular research: GMR

Therapeutic effect of Pleurotus eryngii cellulose on experimental fatty liver in rats.

The aim of this study was to explore the therapeutic effect of Pleurotus eryngii cellulose on experimental fatty liver in rats. Rats were fed high-fat fodder to establish a rat fatty liver model, and were then fed different concentrations of Pleurotus eryngii cellulose for six weeks..

Cordyceps · 2015 · Research Article · Pharmacognosy magazine

A direct protein kinase B-targeted anti-inflammatory activity of cordycepin from artificially cultured fruit body of Cordyceps militaris.

BACKGROUND: Cordyceps militaris is one of well-known medicinal mushrooms with anti-inflammatory, anti-cancer, anti-diabetic, and anti-obesity activities. OBJECTIVE: The objective of the following study is to isolate chemical components from the ethanol extract (Cm-EE) from Cordyceps militaris and to evaluate their….

Cognition & nervesMetabolic healthGut & microbiome

Almond Mushroom · 2015 · Research Article · Evidence-based complementary and alternative medicine: eCAM

Aqueous Extract of Agaricus blazei Murrill Prevents Age-Related Changes in the Myenteric Plexus of the Jejunum in Rats.

This study evaluated the effects of the supplementation with aqueous extract of Agaricus blazei Murrill (ABM) on biometric and blood parameters and quantitative morphology of the myenteric plexus and jejunal wall in aging Wistar rats..

Cordyceps · 2015 · Research Article · Mycobiology

Identification of the Genes Involved in the Fruiting Body Production and Cordycepin Formation of Cordyceps militaris Fungus.

A mutant library of Cordyceps militaris was constructed by improved Agrobacterium tumefaciens-mediated transformation and screened for degradation features. Six mutants with altered characters in in vitro and in vivo fruiting body production, and cordycepin formation were found to contain a single copy T-DNA..

Immune supportCognition & nervesMetabolic health

Mesima · 2015 · Journal Article · Food & function

Structural characterization and immunomodulatory effects of polysaccharides from Phellinus linteus and Phellinus igniarius on the IL-6/IL-10 cytokine balance of the mouse macrophage cell lines (RAW 264.7).

Phellinus linteus and igniarius (L.) Quel. have been used in traditional Asian medicine for over two centuries against a variety of diseases.

Energy & fatigueMetabolic health

King Oyster · 2015 · Journal Article · Annals of animal science

The Effect of Pleurotus Eryngii Stalk Residue Dietary Supplementation on Layer Performance, Egg Traits and Oxidative Status

This study was conducted to investigate the effects of Pleurotus eryngii stalk residue (PESR) on performance, egg traits and oxidative status of laying hens. One hundred and twenty 22-week-old laying hens (Hendrix) were randomly allocated into 4 dietary groups, each containing 30 birds, including 10 replicates per….

Metabolic healthGut & microbiome

Oyster Mushroom · 2015 · Research Article · Mycobiology

The Effects of Temperature and Nutritional Conditions on Mycelium Growth of Two Oyster Mushrooms (Pleurotus ostreatus and Pleurotus cystidiosus).

The influences of temperature and nutritional conditions on the mycelium growth of oyster mushroom Pleurotus ostreatus (PO) and Pleurotus cystidiosus (PC) were investigated in laboratory experiment during the summer season of 2014..

Metabolic healthGut & microbiomeSkin & hydration

King Oyster · 2014 · Journal Article · Plant disease

First Report of Sporobolomyces symmetricus Induced Red Spot Disease of Pleurotus eryngii in China.

Pleurotus eryngii is cultivated on a large scale in China and other Asian countries due to its exceptional flavor and its popularity in cuisine. In January of 2009, red spot disease on cultivated P.

King Oyster · 2014 · Journal Article · International journal of medicinal mushrooms

The effects of the king oyster mushroom Pleurotus eryngii (higher Basidiomycetes) on glycemic control in alloxan-induced diabetic mice.

The purpose of this study is to investigate the effects of Pleurotus eryngii on glycemic metabolism. Alloxan-induced hyperglycemic mice were used to study the effects of P..

Immune supportCognition & nervesMetabolic healthLiver support

Maitake · 2013 · Journal Article · Food and agricultural immunology

Antioxidant and immunomodulatory effects of a α-glucan from fruit body of maitake (Grifola frondosa)

The antioxidant and immunomodulatory effect of an α-glucan (designated here as MT-α-glucan) from fruit body of Maitake mushroom (Grifola frondosa) on D-galactose (D-gal)-induced senescent mice model was evaluated..

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

Almond Mushroom · 2013 · Journal Article · Obesity (Silver Spring, Md.)

Dietary supplementation with Agaricus blazei murill extract prevents diet-induced obesity and insulin resistance in rats.

OBJECTIVE: Dietary supplement may potentially help to fight obesity and other metabolic disorders such as insulin-resistance and low-grade inflammation. The present study aimed to test whether supplementation with Agaricus blazei murill (ABM) extract could have an effect on diet-induced obesity in rats..

Immune supportMetabolic healthLiver support

Maitake · 2013 · Journal Article · Journal of oleo science

Effect of Dietary Maitake (Grifola frondosa) Mushrooms on Plasma Cholesterol and Hepatic Gene Expression in Cholesterol-Fed Mice

To investigate the effects of dietary Grifola frondosa on cholesterol, normal mice were fed a diet containing 1% cholesterol (HC group) or 1% cholesterol and 10% freeze-dried G..

Chaga · 2013 · Journal Article · Food research international (Ottawa, Ont.)

Effect of different drying methods on physicochemical properties and antioxidant activities of polysaccharides extracted from mushroom Inonotus obliquus

Inonotus obliquus is a kind of mushroom which has long been used as a folk remedy for curing various diseases such as cancers, heart disease and diabetes in Russian and Eastern Europe. Polysaccharides are one of the main bioactive constituents of Inonotus obliquus with health functions..

Shiitake · 2013 · Journal Article · Journal of wood science

Effect of increased harvests on saccharification ratio of waste mushroom medium from the cultivation of shiitake mushroom (Lentinula edodes)

Waste mushroom medium (WM) was saccharized with cellulase to obtain glucose after shiitake fruiting bodies were harvested 3 and 5 times (WM-3 and WM-5, respectively). Glucose can be used as a feedstock for the production of bioethanol or other bioproducts..