MycoData

After decades of utilization of fossil-based and environmentally hazardous compounds for wood preservation against fungal attack, there is a strong need to substitute those compounds with bio-based bioactive solutions, such as essential oils..

Liver support

Medium relevance

Reishi · 2023 · Journal Article · Pharmaceutical biology

Lucialdehyde B suppresses proliferation and induces mitochondria-dependent apoptosis in nasopharyngeal carcinoma CNE2 cells.

CONTEXT: Lucialdehyde B (LB), an effective triterpenoid isolated from Ganoderma lucidum (Leyss. ex Fr.) Karst.

OncologyEnergy & fatigueGut & microbiome

Medium relevance

Oyster Mushroom · 2023 · Journal Article · Frontiers in microbiology

Mechanism of fungal remediation of wetland water: Stropharia rugosoannulata as promising fungal species for the development of biofilters to remove clinically important pathogenic and antibiotic resistant bacteria in contaminated water.

Mycoremediation uses mushroom forming fungi for remediation of sites contaminated with biotic and abiotic contaminants. The root-like hyphae of many fungi, the mycelia, have been used to remediate soil and water..

Respiratory

Medium relevance

Mesima · 2023 · Research Article · Biomedicines

Methoxyhispolon Methyl Ether, a Hispolon Analog, Thwarts the SRC/STAT3/BCL-2 Axis to Provoke Human Triple-Negative Breast Cancer Cell Apoptosis In Vitro.

Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer with few treatment options. A promising TNBC treatment approach is targeting the oncogenic signaling pathways pivotal to TNBC initiation and progression..

OncologyImmune support

Medium relevance

Oyster Mushroom · 2023 · Journal Article · Applied soil ecology: a section of Agriculture, Ecosystems & Environment

Microbial inoculation influences microbial communities and physicochemical properties during lettuce seedling using composted spent mushroom substrate

Massive spent mushroom substrate (SMS) has become an important problem that affects the ecological environment and restricts the development of mushroom industry..

Gut & microbiome

Medium relevance

Chaga · 2023 · Research Article · Materials (Basel, Switzerland)

Microwave-Assisted Fabrication of Fugus-Based Biocarbons for Malachite Green and NO2 Removal.

The aim of the current study was to produce biocarbons through the activation of carbon dioxide with the extraction residues of the fungus Inonotus obliquus. To achieve this goal, a microwave oven was used to apply three different activation temperatures: 500, 600, and 700 °C..

Energy & fatigue

Medium relevance

Reishi · 2023 · Journal Article · Current issues in molecular biology

Mixed Medicinal Mushroom Mycelia Attenuates Alzheimer's Disease Pathologies In Vitro and In Vivo.

Alzheimer's disease (AD) is characterized by memory impairment and existence of amyloid-β (Aβ) plaques and neuroinflammation. Due to the pivotal role of oxidative damage in AD, natural antioxidative agents, such as polyphenol-rich fungi, have garnered scientific scrutiny..

OncologyImmune supportCognition & nervesEnergy & fatigue

Medium relevance

Enoki · 2023 · Research Article · Journal of fungi (Basel, Switzerland)

Molecular and Functional Analyses of Characterized Sesquiterpene Synthases in Mushroom-Forming Fungi.

Sesquiterpenes are a type of abundant natural product with widespread applications in several industries. They are biosynthesized by sesquiterpene synthases (STSs).

Metabolic health

Medium relevance

Oyster Mushroom · 2023 · Journal Article · Plant Pathology

Molecular characterization of Trichoderma spp. isolates in mushroom‐growing farms in Turkey and their effects on Agaricus bisporus production

Mushroom production is highly affected by green mould disease, which causes severe losses worldwide. This study aimed to characterize Trichoderma spp.

Medium relevance

Reishi · 2023 · Journal Article · Nutrients

Mushroom-Based Supplements in Italy: Let's Open Pandora's Box.

Mushrooms and derivates are well known to the scientific community for having different health benefits and exhibit a wide range of pharmacological activities, including lipid-lowering, antihypertensive, antidiabetic, antimicrobic, antiallergic, anti-inflammatory, anticancer, immunomodulating, neuroprotective and….

OncologyImmune supportCognition & nervesMetabolic health

Medium relevance

Reishi · 2023 · Journal Article · International journal of medicinal mushrooms

Mushroom-Related Ethnomycological, Ethnomedical, and Socio-Economic Practices in Nigeria.

Native mushrooms are valuable non-timber forest products used worldwide, although they are under-exploited in Africa. This study focused on evaluating ethnomycological practices in Nigeria.

Metabolic healthSkin & hydration

Medium relevance

Reishi · 2023 · Journal Article · Frontiers in bioengineering and biotechnology

Mycelium-based biomaterials as smart devices for skin wound healing.

Introduction: Recently, mycelia of Ganoderma lucidum and Pleurotus ostreatus, edible fungi, have been characterized in vitro as self-growing biomaterials for tissue engineering since they are constituted of interconnected fibrous networks resembling the dermal collagen structure..

Skin & hydration

Medium relevance

Reishi · 2023 · Journal Article · Frontiers in nutrition

Network pharmacology-based analysis of Resinacein S against non-alcoholic fatty liver disease by modulating lipid metabolism.

BACKGROUND: Ganoderma lucidum is reportedly the best source of traditional natural bioactive constituents. Ganoderma triterpenoids (GTs) have been verified as an alternative adjuvant for treating leukemia, cancer, hepatitis and diabetes..

OncologyEnergy & fatigueMetabolic healthLiver support

Medium relevance

Reishi · 2023 · Journal Article · Journal of Alzheimer's disease reports

Neuroprotective Effects of a Multi-Herbal Extract on Axonal and Synaptic Disruption in Vitro and Cognitive Impairment in Vivo.

BACKGROUND: Alzheimer's disease (AD) is a multifactorial disorder characterized by cognitive decline. Current available therapeutics for AD have limited clinical benefit.

Cognition & nervesEnergy & fatigue

Medium relevance

Lion's Mane · 2023 · Research Article · International journal of molecular sciences

Neuroprotective Effects of Erinacine A on an Experimental Model of Traumatic Optic Neuropathy.

Erinacine A (EA), a natural neuroprotectant, is isolated from a Chinese herbal medicine, Hericium erinaceus. The aim of this study was to investigate the neuroprotective effects of EA in a rat model of traumatic optic neuropathy..

OncologyImmune supportCognition & nervesEnergy & fatigue

Medium relevance

Niu-Chang-Chih · 2023 · Journal Article · Phytomedicine: international journal of phytotherapy and phytopharmacology

Ovatodiolide and antrocin synergistically inhibit the stemness and metastatic potential of hepatocellular carcinoma via impairing ribosome biogenesis and modulating ERK/Akt-mTOR signaling axis.

Activation of mitogen-activated protein kinase (MAPK) and PI3K signaling confers resistance against sorafenib, a mainstay treatment for advanced hepatocellular carcinoma (HCC)..

OncologyGut & microbiomeLiver support

Medium relevance

Oyster Mushroom · 2023 · Journal Article · International journal of medicinal mushrooms

Phenolic Content, Antibacterial and Antioxidant Potential of Several Edible Agaricomycetes Mushrooms Sold in Public Bazaar in Bolu, Turkey.

Edible mushrooms are important natural foods that have been used since ancient times due to their delicious taste, high nutritional value, and various biological activities..

Skin & hydration

Medium relevance

Turkey Tail · 2023 · Research Article · Journal of fungi (Basel, Switzerland)

Phenothiazines Rapidly Induce Laccase Expression and Lignin-Degrading Properties in the White-Rot Fungus Phlebia radiata.

Phlebia radiata is a widespread white-rot basidiomycete fungus with significance in diverse biotechnological applications due to its ability to degrade aromatic compounds, xenobiotics, and lignin using an assortment of oxidative enzymes including laccase..

Medium relevance

Lion's Mane · 2023 · Research Article · Polymers

Physicochemical Characterization and Antimicrobial Analysis of Vegetal Chitosan Extracted from Distinct Forest Fungi Species.

The main goal of this investigation is to conduct a thorough analysis of the physical, chemical, and morphological characteristics of chitosan derived from various forest fungi. Additionally, the study aims to determine the effectiveness of this vegetal chitosan as an antimicrobial agent..

Energy & fatigueGut & microbiomeSkin & hydration

Medium relevance

Reishi · 2023 · Journal Article · Frontiers in endocrinology

Proteomics and network pharmacology of Ganshu Nuodan capsules in the prevention of alcoholic liver disease.

INTRODUCTION: Ganshu Nuodan is a liver-protecting dietary supplement composed of Ganoderma lucidum (G. lucidum) spore powder, Pueraria montana (Lour.) Merr.

OncologyLiver support

Medium relevance

Reishi · 2023 · Journal Article · Frontiers in cellular and infection microbiology

Red recombination enables a wide variety of markerless manipulation of porcine epidemic diarrhea virus genome to generate recombinant virus.

Porcine epidemic diarrhea virus (PEDV) is a member of the genera Alphacoronavirus that has been associated with acute watery diarrhea and vomiting in swine. Unfortunately, no effective vaccines and antiviral drugs for PEDV are currently available.

Respiratory

Medium relevance

Shiitake · 2023 · Research Article · Antioxidants (Basel, Switzerland)

Scanning Electron Microscopy and Triple TOF-LC-MS-MS Analysis of Polyphenols from PEF-Treated Edible Mushrooms (L. edodes, A. brunnescens, and P. ostreatus).

Pulsed electric fields (PEF) technology has been used as a sustainable method for extracting antioxidant bioactive compounds from different food matrices. In the present study, the optimal conditions of PEF extraction for mushrooms (2.5 kV/cm, 50 kJ/kg, 6 h) were applied to Lentinula edodes, Agaricus brunnescens, and….

Energy & fatigue

Medium relevance

Lion's Mane · 2023 · Journal Article · International journal of biological macromolecules

Semi-solid enzymolysis enhanced the protective effects of fruiting body powders and polysaccharides of Herinaceus erinaceus on gastric mucosal injury.

This study demonstrated the effects of semi-solid enzymolysis on physicochemical properties of fruiting body powders and polysaccharides from Hericium erinaceus and protective effects on gastric mucosal injury..

OncologyImmune supportGut & microbiome

Medium relevance

Reishi · 2023 · Journal Article · Analytical biochemistry

SERS-substrates based on ZnO nanoflowers prepared by green synthesis.

ZnO nanoparticles (NPs) with a flower-like morphology, synthesized by an affordable colloidal route using an aqueous fungi extract of Ganoderma lucidum as a reducing agent and stabilizer, are investigated as SERS-substrate..

Medium relevance

Turkey Tail · 2023 · Research Article · Molecules (Basel, Switzerland)

Smartphone-Based Electrochemical Biosensor for On-Site Nutritional Quality Assessment of Coffee Blends.

This work aimed to develop an easy-to-use smartphone-based electrochemical biosensor to quickly assess a coffee blend's total polyphenols (Phs) content at the industrial and individual levels..

Cognition & nervesEnergy & fatigue

Medium relevance

Oyster Mushroom · 2023 · Research Article · Water research X

Sorghum-grown fungal biocatalysts for synthetic dye degradation.

The synthetic dye discharge is responsible for nearly one-fifth of the total water pollution from textile industry, which poses both environmental and public health risks..

Medium relevance

Reishi · 2023 · Journal Article · Antioxidants (Basel, Switzerland)

Spore Oil-Functionalized Selenium Nanoparticles Protect Pancreatic Beta Cells from Palmitic Acid-Induced Apoptosis via Inhibition of Oxidative Stress-Mediated Apoptotic Pathways.

Oxidative stress damage of pancreatic β-cells is a key link in the pathogenesis of type 2 diabetes mellitus. A long-term increase of free fatty acids induces the increase of reactive oxygen species (ROS) in β-cells, leading to apoptosis and dysfunction of β-cells..

OncologyEnergy & fatigueMetabolic health

Medium relevance

Oyster Mushroom · 2023 · Research Article · Polymers

Suitability of Mycelium-Reinforced Nanofiber Mats for Filtration of Different Dyes.

Electrospun nanofiber mats have a high specific surface area and very small pores which can be tailored by the spinning process. They are thus highly suitable as filters for small particles and molecules, such as organic dyes.

Medium relevance

Reishi · 2023 · Journal Article · Water environment research: a research publication of the Water Environment Federation

Supplementation of 5-deoxystrigol for higher pollutant removal and biogas quality improvement by different microalgae-based technologies.

The treatment of biogas slurry by microalgae technology has the characteristics of low cost, environmental protection, and high efficiency. In this paper, the effects of four microalgae technologies, namely, monoculture of Scenedesmus obliquus (S.

Energy & fatigue

Medium relevance

Snow Fungus · 2023 · Research Article · Food science & nutrition

Synergistic mediating effect of edible fungal polysaccharides (Auricularia and Tremellan) and Crataegus flavonoids in hyperlipidemic rats.

Both edible fungal polysaccharides (Auricularia and Tremellan) and Crataegus flavonoids promote the balance of dyslipidemia, which have a positive biological regulating effect on intestinal flora..

Immune supportMetabolic healthGut & microbiomeLiver support

Medium relevance

Turkey Tail · 2023 · Journal Article · Food chemistry

Target directed identification of natural bioactive compounds from filamentous fungi.

Some of the most powerful natural antimicrobial compounds originate from filamentous fungi. However, due to the diversity of compounds from plant and fungal origin, separation, isolation, and identification of bioactive constituents can be a long and tedious process..

Energy & fatigue

Medium relevance

Oyster Mushroom · 2023 · Research Article · Mitochondrial DNA. Part B, Resources

The complete mitochondrial genome of Triplax ainonia Lewis, 1877 (Coleoptera: Erotylidae).

The beetle Triplax ainonia Lewis, 1877 is a serious pest of cultivated the mushroom Pleurotus ostreatus in China. The complete mitochondrial genome of this species was reported for the first time in this study..

Energy & fatigue

Medium relevance

Snow Fungus · 2023 · Journal Article · International journal of food science & technology

The effect of different edible fungal polysaccharides on the stability of whey protein isolate solution near isoelectric point

Whey protein isolate (WPI) is unstable near isoelectric point with simultaneous precipitation or phase separation, which negatively affects its application. In the current study, four kinds of edible fungal polysaccharides were selected to improve the WPI stability through non‐covalent interaction..

Immune support

Medium relevance

Reishi · 2023 · Journal Article · Bioresource technology

The effects of influent chemical oxygen demand and strigolactone analog concentration on integral biogas upgrading and pollutants removal from piggery wastewater by different microalgae-based technologies.

Microalgae-based technologies are promising strategies for efficient wastewater treatment and biogas upgrading. In this study, three types of microalga-fungi/bacteria symbiotic systems stimulated with the strigolactone analog (GR24) were used to simultaneously remove nutrients from treated piggery wastewater and CO2….

Energy & fatigue

Medium relevance

Reishi · 2023 · Journal Article · Journal of neuroimmunology

The mechanism of LZ-8-mediated immune response in the mouse model of Parkinson's disease.

Parkinson's disease (PD) is associated with microscopic changes in the brain, particularly substantia nigra (SN). Ganoderma lucidum immunoregulatory protein (rLZ-8) is might confer protective effects against PD..

Immune supportCognition & nerves

Medium relevance

Turkey Tail · 2023 · Research Article · Molecules (Basel, Switzerland)

The Synergistic Effect of Biosynthesized Silver Nanoparticles and Phytocompound as a Novel Approach to the Elimination of Pathogens.

Due to the wide applications of silver nanoparticles (AgNPs), research on their ecological synthesis has been extensive in recent years. In our study, biogenic silver nanoparticles were synthesized extracellularly using the white rot fungus Trametes versicolor via two cultivation methods: static and shaking..

Oncology

Medium relevance

Reishi · 2023 · Journal Article · Nature materials

Three-dimensional printing of mycelium hydrogels into living complex materials.

Biological living materials, such as animal bones and plant stems, are able to self-heal, regenerate, adapt and make decisions under environmental pressures. Despite recent successful efforts to imbue synthetic materials with some of these remarkable functionalities, many emerging properties of complex adaptive….

Gut & microbiomeSkin & hydration

Medium relevance

Reishi · 2023 · Journal Article · Foods (Basel, Switzerland)

Traditional Uses of Wild Edible Mushrooms among the Local Communities of Swat, Pakistan.

Mushrooms play a crucial role in human life as well as in nature, providing food, medicine, and carrying out vital processes of decomposition, nutrient recycling, and developing mycorrhizal association with plants..

Medium relevance

Reishi · 2023 · Journal Article · Gene

Transcriptome profiling and bioinformatic analysis of the effect of ganoderic acid T prevents Sendai virus infection.

Ganoderic acid T (GA-T) is an important triterpene of Ganoderma lucidum, which is utilized to treat viral infections. Sendai virus (SeV) is widely studied to determine the molecular biological characteristics of RNA viruses and employed to elucidate the mechanisms governing the innate immune response..

Immune supportRespiratory

Medium relevance

Turkey Tail · 2023 · Research Article · Journal of the American Chemical Society

Tuning the Type 1 Reduction Potential of Multicopper Oxidases: Uncoupling the Effects of Electrostatics and H-Bonding to Histidine Ligands.

In multicopper oxidases (MCOs), the type 1 (T1) Cu accepts electrons from the substrate and transfers these to the trinuclear Cu cluster (TNC) where O2 is reduced to H2O. The T1 potential in MCOs varies from 340 to 780 mV, a range not explained by the existing literature..

Medium relevance

Oyster Mushroom · 2023 · Journal Article · Chemosphere

Various species of Basidiomycota fungi reveal different abilities to degrade pharmaceuticals and also different pathways of degradation.

The presence of pharmaceuticals (PhACs) in the aquatic environment is an emerging problem worldwide. PhACs reach surface water via the effluents of wastewater treatment plants (WWTPs).

Immune supportCognition & nerves

Medium relevance

Enoki · 2023 · Research Article · Journal of fungi (Basel, Switzerland)

Whole Genome Sequence of an Edible Mushroom Oudemansiella raphanipes (Changgengu).

Oudemansiella raphanipes, considered as a well-known culinary edible mushroom with a high content of natural bioactive substances, is widely cultivated in China with the commercial name Changgengu. However, due to the lack of genomic data, molecular and genetic study on O.

Medium relevance

Turkey Tail · 2023 · Research Article · International journal of analytical chemistry

Wild Mushrooms: A Hidden Treasure of Novel Bioactive Compounds.

Secondary metabolites are hidden gems in mushrooms. Understanding these secondary metabolites' biological and pharmacological effects can be aided by identifying them..

OncologyImmune supportMetabolic health

Medium relevance

Turkey Tail · 2023 · Research Article · Evidence-based complementary and alternative medicine: eCAM

Wild Mushrooms: Potential Natural Sources of Antioxidant and Anti-Quorum Sensing Bioactive Compounds for Medical Applications.

OBJECTIVE: This study was aimed at determining the antioxidant, anti-quorum sensing, and in vitro cytotoxic activities of five wild mushroom extracts. METHODS: Wild mushrooms of Auricularia auricula-judae, Termitomyces umkowaani, Trametes elegans, Trametes versicolor, and Microporus xanthopus were collected from….

Oncology

Medium relevance

Turkey Tail · 2023 · Research Article · Journal of fungi (Basel, Switzerland)

Wood Degradation by Fomitiporia mediterranea M. Fischer: Exploring Fungal Adaptation Using Metabolomic Networking.

Fomitiporia mediterranea M. Fischer (Fmed) is a white-rot wood-decaying fungus associated with one of the most important and challenging diseases in vineyards: Esca.

Medium relevance

Turkey Tail · 2023 · Research Article · Materials (Basel, Switzerland)

Wood-Decaying Fungi: From Timber Degradation to Sustainable Insulating Biomaterials Production.

Addressing the impacts of climate change and global warming has become an urgent priority for the planet's well-being. In recent decades the great potential of fungal-based products with characteristics equal to, or even outperforming, classic petroleum-derived products has been acknowledged..

Energy & fatigue

Medium relevance

Turkey Tail · 2023 · Research Article · Polymers

ZnO Treatment on Mechanical Behavior of Polyethylene/Yellow Birch Fiber Composites When Exposed to Fungal Wood Rot.

Wood plastic composite (WPC) usage and demand have increased because of its interesting chemical and mechanical properties compared to other plastic materials. However, there is a possibility of structural and mechanical changes to the material when exposed to the external environment; most research on wood plastic is….

Medium relevance

Chaga · 2022 · Journal Article · Fitoterapia

21,24-Cyclolanostanes revisited: Structural revision and biological evaluation.

Chemical fractionation of the EtOH extract of a medicinal macro fungus, Inonotus obliquus, afforded an array of lanostane-type triterpenoids (1-11) including two new ones (1 and 8)..

Oncology

Medium relevance

Turkey Tail · 2022 · Journal Article · Journal of biotechnology

3D printed PLA enzyme microreactors: Characterization and application for the modification of bioactive compounds.

Process sustainability of biocatalytic processes is significantly empowered with the use of continuous-flow technologies that offer high productivity, minimal wastes and low volumetric consumption. Combining microreactor design with 3D printing technology can broaden the engineering potentials..

Energy & fatigue

Medium relevance

Oyster Mushroom · 2022 · Journal Article · Scientific reports

A comparative screening of laccase-mediator systems by white-rot fungi laccases for biocatalytic benzyl alcohol oxidation.

Production of value-added compounds from waste materials is of utmost importance for the development of a sustainable society especially regarding their use as catalysts in industrially relevant synthetic reactions..

Energy & fatigue