MycoData

OncologyCognition & nerves

Lion's Mane · 2015 · Research Support, Non U.S. Gov'T · Food chemistry

Isolation and identification of aromatic compounds in Lion's Mane Mushroom and their anticancer activities.

Lion's Mane Mushroom (Hericium erinaceum) is a traditional edible mushroom widely used in culinary applications and as an herbal medicine in East Asian countries..

Wood Ear · 2013 · Research Support, Non U.S. Gov'T · International journal of medicinal mushrooms

Heat-stable components of wood ear mushroom, Auricularia polytricha (higher Basidiomycetes), inhibit in vitro activity of beta secretase (BACE1).

The consumption of mushrooms has been linked with protection against dementia, including Alzheimer's disease (AD), by several biological pathways including inhibiting beta-site APP-cleaving enzyme (BACE1), which is responsible for releasing toxic β-amyloid peptide in the brain..

Almond Mushroom · 2026 · Case Study · Case reports in orthopedics

Lumbar Plexopathy and Exploration Following an Oblique Lumbar Interbody Fusion (OLIF) iFactor-Associated Complication: A Case Report.

BACKGROUND: Oblique lumbar interbody fusion (OLIF) is a minimally invasive surgical technique used for lumbar spine stabilisation, known for reducing the morbidity associated with traditional posterior lumbar fusion techniques..

Cognition & nervesRespiratory

Almond Mushroom · 2026 · Case Reports · Radiology case reports

Purulent Streptococcus Pneumoniae meningitis with suppurative focus and infectious vasculitis leading to ischemic and hemorrhagic strokes: A rare case report.

Acute bacterial meningitis (ABM) is a neurological emergency that continues to cause high levels of morbidity and mortality worldwide. Despite advances in antimicrobial therapy and vaccination, it continues to cause severe neurological sequelae..

Almond Mushroom · 2025 · Article Commentary · Journal of traumatic stress

Expanding the framework of attention in posttraumatic stress disorder: Commentary on Clauss et al. (2025).

This commentary expands on Clauss et al.'s (2025) meta-analysis of attention control training (ACT) for posttraumatic stress disorder (PTSD) by situating ACT and related interventions within a broader framework of attentional functioning..

Cognition & nervesMetabolic health

Cordyceps · 2025 · Brief Report · Pharmacology research & perspectives

Exploring Cordycepin as a Neuroprotective Agent in Huntington's Disease: In Vitro and In Vivo Insights.

Huntington's disease (HD) is a challenging neurodegenerative disorder linked to Huntingtin (HTT) gene mutation, lacking an effective cure despite numerous therapeutic attempts..

Almond Mushroom · 2024 · Research Support, Non U.S. Gov'T · Journal of the Royal Society, Interface

An in vitro agent-based modelling approach to optimization of culture medium for generating muscle cells.

Methodologies for culturing muscle tissue are currently lacking in terms of quality and quantity of mature cells produced. We analyse images from in vitro experiments to quantify the effects of culture media composition on mouse-derived myoblast behaviour and myotube quality..

Almond Mushroom · 2023 · Research Article · Frontiers in human neuroscience

Attentional bias to threat is modulated by stimulus content: an fNIRS study.

People are evolutionarily predisposed to associate threat relevant stimuli with fear or aversiveness and show an attentional bias toward threat. Attentional bias modification (ABM) has been shown to reduce threat biases, while quantitative reviews assessing the effectiveness of bias modification yielded inconsistent….

Cognition & nervesEnergy & fatigueGut & microbiomeRespiratory

Reishi · 2023 · Journal Article · Frontiers in nutrition

Chronic supplementation of a multi-ingredient herbal supplement increases speed of cognitive task performance alongside changes in the urinary metabolism of dopamine and the gut microbiome in cognitively intact older adults experiencing subjective memory decline: a randomized, placebo controlled, parallel groups investigation.

BACKGROUND: The effects of herbs on brain function are often investigated in isolation, yet herbal preparations are often complex combinations of phytochemicals, designed to target widespread mechanisms..

Oyster Mushroom · 2023 · Journal Article · Foods (Basel, Switzerland)

Developments of Plant-Based Emulsion-Type Sausage by Using Grey Oyster Mushrooms and Chickpeas.

Plant-based (PB) meat alternatives are developing due to the consumer's demand, especially those who are mainly health-concerned. Soy proteins (SP) are commonly used as the main ingredients for PB meat analogues; however, SP may have adverse effects on the cognitive function and mood of humans..

Almond Mushroom · 2023 · Journal Article · Annals of biomedical engineering

Evaluation of Deep Brain Stimulation (DBS) Lead Biomechanical Interaction with Brain Tissue.

The current study aims to examine the effect of material properties on implanted leads used for deep brain stimulation (DBS) using finite element (FE) analysis to investigate brain deformation around an implanted DBS lead in response to daily head accelerations..

Cordyceps · 2023 · Journal Article · Neural regeneration research

Fingolimod protects against neurovascular unit injury in a rat model of focal cerebral ischemia/reperfusion injury.

Recent research on the underlying mechanisms of cerebral ischemia indicates that the neurovascular unit can be used as a novel subject for general surveys of neuronal damage and protein mechanisms..

Cognition & nervesMetabolic healthGut & microbiome

Cordyceps · 2023 · Journal Article · Frontiers in pharmacology

Harder, better, faster, stronger? Retrospective chart review of adverse events of interactions between adaptogens and antidepressant drugs.

Aim: We aimed to systematically evaluate the prevalence and clinical characteristics of adverse events associated with the adaptogens and antidepressant drug interactions in a retrospective chart review. Methodology: A total of 1,816 reports of adverse events were evaluated..

Almond Mushroom · 2023 · Journal Article · Risk analysis: an official publication of the Society for Risk Analysis

Individual learning as a driver of changes in community vulnerability under repeated hurricanes and changing climate.

The risks from singular natural hazards such as a hurricane have been extensively investigated in the literature. However, little is understood about how individual and collective responses to repeated hazards change communities and impact their preparation for future events..

Almond Mushroom · 2023 · Journal Article · Cognitive neurodynamics

Memristive competitive hopfield neural network for image segmentation application.

Image segmentation implementation provides simplified and effective feature information of image. Neural network algorithms have made significant progress in the application of image segmentation task..

Shiitake · 2023 · Journal Article · Environmental research

New use for Lentinus edodes bran biochar for tetracycline removal.

The abuse of antibiotics poses a threat to the ecological environment and biological health, and how to effectively reduce the residue of tetracycline (TC) in the environment has attracted much attention..

Cognition & nervesSkin & hydration

Oyster Mushroom · 2023 · Journal Article · European spine journal: official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society

Reducing the learning curve of interlaminar full-endoscopic discectomy: mushroom model-simulation training.

PURPOSE: To describe a cheap simulation model used to reduce the learning curve of the interlaminar full-endoscopic discectomy in a pilot study. INTRODUCTION: The steep and difficult learning curve remain one of the main obstacles against the widespread diffusion of interlaminar full endoscopic lumbar discectomy….

Immune supportCognition & nervesEnergy & fatigueRespiratory

Almond Mushroom · 2023 · Journal Article · Cytokine

The neurotoxic branch of the kynurenine pathway is highly activated in the central nervous system of patients with pneumococcal meningitis.

BACKGROUND: Acute bacterial meningitis (ABM) causes excessive activation of N-methyl-D-aspartate receptors (NMDAr), leading to cortical and hippocampal neuron death. As opposite, enteroviral meningitis is more frequently benign..

Cognition & nervesRespiratory

Almond Mushroom · 2022 · Journal Article · Infectious Disease Modelling

Agent-based modeling of COVID-19 outbreaks for New York state and UK: Parameter identification algorithm.

This paper uses Covasim, an agent-based model (ABM) of COVID-19, to evaluate and scenarios of epidemic spread in New York State (USA) and the UK. Epidemiological parameters such as contagiousness (virus transmission rate), initial number of infected people, and probability of being tested depend on the region's….

Almond Mushroom · 2022 · Journal Article · International breastfeeding journal

Complications and misdiagnoses associated with infant frenotomy: results of a healthcare professional survey.

BACKGROUND: In the past 10-15 years, there has been increased concern about ankyloglossia and its effect on infant breastfeeding. This has been associated with increased performance of frenotomy..

Cordyceps · 2022 · Journal Article · Biochemical pharmacology

Cordycepin prevents and ameliorates experimental autoimmune encephalomyelitis by inhibiting leukocyte infiltration and reducing neuroinflammation.

Multiple sclerosis (MS) is a neuroinflammatory autoimmune disease characterized by multifocal perivascular infiltration of immune cells in the central nervous system (CNS)..

OncologyCognition & nerves

Cordyceps · 2022 · Journal Article · Frontiers in aging neuroscience

Integration of network pharmacology and molecular docking to explore the molecular mechanism of Cordycepin in the treatment of Alzheimer's disease.

BACKGROUND: Cordycepin is a nucleoside adenosine analog and an active ingredient isolated from the liquid fermentation of Cordyceps. This study sought to explore the mechanism underlying the therapeutic effect of Cordycepin against Alzheimer's disease using network pharmacology and molecular docking technology..

Immune supportCognition & nervesRespiratory

Almond Mushroom · 2022 · Journal Article · Microbial pathogenesis

Non-steroidal anti-inflammatory drugs ketorolac and etodolac can augment the treatment against pneumococcal meningitis by targeting penicillin-binding proteins.

BACKGROUND: Streptococcus pneumoniae is the principal etiological agent of acute bacterial meningitis (ABM) which has fatal outcome in children and elderly. Due to poor blood-brain barrier (BBB) permeation, conventional β-lactam antibiotics fail to establish the requisite bactericidal concentration in central nervous….

Lion's Mane · 2021 · Research Article · Scientific reports

Adults who microdose psychedelics report health related motivations and lower levels of anxiety and depression compared to non-microdosers.

The use of psychedelic substances at sub-sensorium 'microdoses', has gained popular academic interest for reported positive effects on wellness and cognition. The present study describes microdosing practices, motivations and mental health among a sample of self-selected microdosers (n = 4050) and non-microdosers (n =….

Almond Mushroom · 2021 · Journal Article · Frontiers in neuroscience

Alterations in Electroencephalography Theta as Candidate Biomarkers of Acute Cannabis Intoxication.

The trend toward cannabis legalization in the United States over the past two decades has unsurprisingly been accompanied by an increase in the number of cannabis users and use patterns that potentially pose wider risks to the public like driving under the influence..

Almond Mushroom · 2021 · Journal Article · Annals of biomedical engineering

Brain Strain: Computational Model-Based Metrics for Head Impact Exposure and Injury Correlation.

Athletes participating in contact sports are exposed to repetitive subconcussive head impacts that may have long-term neurological consequences. To better understand these impacts and their effects, head impacts are often measured during football to characterize head impact exposure and estimate injury risk..

Almond Mushroom · 2021 · Journal Article · Exploratory research in clinical and social pharmacy

Factors associated with oral fingolimod use over injectable disease- modifying agent use in multiple sclerosis.

BACKGROUND: Fingolimod is the first approved oral disease-modifying agent (DMA) in 2010 to treat Multiple Sclerosis (MS). There is limited real-world evidence regarding the determinants associated with fingolimod use in the early years..

Immune supportCognition & nervesSkin & hydration

Almond Mushroom · 2021 · Journal Article · Simulation

Nested active learning for efficient model contextualization and parameterization: pathway to generating simulated populations using multi-scale computational models.

There is increasing interest in the use of mechanism-based multi-scale computational models (such as agent-based models (ABMs)) to generate simulated clinical populations in order to discover and evaluate potential diagnostic and therapeutic modalities..

Almond Mushroom · 2021 · Journal Article · Journal of Intelligence

The Role of General and Specific Cognitive Abilities in Predicting Performance of Three Occupations: Evidence from Bifactor Models.

Cognitive abilities are related to job performance. However, there is less agreement about the relative contribution of general versus specific cognitive abilities to job performance.

Almond Mushroom · 2021 · Journal Article · Journal of archaeological method and theory

Theoretical and Methodological Approaches to Ecological Changes, Social Behaviour and Human Intergroup Tolerance 300,000 to 30,000 BP.

UNLABELLED: Archaeological evidence suggests that important shifts were taking place in the character of human social behaviours 300,000 to 30,000 years ago. New artefact types appear and are disseminated with greater frequency..

Oyster Mushroom · 2020 · Video Audio Media · Proceedings of the National Academy of Sciences of the United States of America

Sensory cilia as the Achilles heel of nematodes when attacked by carnivorous mushrooms.

Fungal predatory behavior on nematodes has evolved independently in all major fungal lineages. The basidiomycete oyster mushroom Pleurotus ostreatus is a carnivorous fungus that preys on nematodes to supplement its nitrogen intake under nutrient-limiting conditions..

Lion's Mane · 2023 · Research Support, Non U.S. Gov'T · Journal of neurochemistry

Hericerin derivatives activates a pan-neurotrophic pathway in central hippocampal neurons converging to ERK1/2 signaling enhancing spatial memory.

The traditional medicinal mushroom Hericium erinaceus is known for enhancing peripheral nerve regeneration through targeting nerve growth factor (NGF) neurotrophic activity. Here, we purified and identified biologically new active compounds from H..

Mesima · 2022 · Research Support, Non U.S. Gov'T · Archives of biochemistry and biophysics

Hispolon alleviates oxidative damage by stimulating the Nrf2 signaling pathway in PC12 cells.

Natural products derived from the daily diet are garnering increasing attention for neurodegenerative disease (ND) treatment. Hispolon (His), a small molecule from Phellinus linteus, has been reported to have various pharmacological activities..

Lion's Mane · 2022 · Research Support, Non U.S. Gov'T · The Journal of organic chemistry

Total Synthesis of Isohericerinol A and Its Analogues to Access Their Potential Neurotrophic Effects.

The secondary metabolites from Hericium erinaceus are well-known to have neurotrophic and neuroprotective effects. Isohericerinol A (1), isolated by our colleagues from its fruiting parts has a strong ability to increase the nerve growth factor secretion in C6 glioma cells..

Lion's Mane · 2021 · Research Support, Non U.S. Gov'T · The Journal of organic chemistry

Total Synthesis, Structure Revision, and Neuroprotective Effect of Hericenones C-H and Their Derivatives.

The first total syntheses of hericenones C-H and "putative 3-hydroxyhericenone F" were achieved. Highlights of the synthesis include the straightforward construction of the resorcinol core and geranyl side chain, assembly of the natural product skeleton by sequential O-geranylation and a clay/zeolite-mediated O → C….

Zhu Ling · 2010 · Patent · journal metadata

Chestnutsdispe capsule and preparation method thereof

The invention relates to a chestnutsdispe capsule and a preparation method thereof. The chestnutsdispe capsule is prepared from the following materials: 15-25% of tuckahoe, 15-25% of Polyporus umbellatus, 15-25% of rhizoma atractylodis macrocephalae (fried), 25-35% of rhizoma alismatis and 10-15% of cinnamon..

Immune supportCognition & nervesEnergy & fatigue

Chaga · 2010 · Patent · journal metadata

Product for enhancing organic immunity and improving sleeping quality and preparation method thereof

The invention relates to a product for enhancing organic immunity and improving sleeping quality and a preparation method thereof, which belong to the field of functional health foods..

OncologyImmune supportCognition & nervesEnergy & fatigue

Mesima · 2008 · Patent · journal metadata

ANTIOXIDANT COMPOSITION CONTAINING HISPIDIN DERIVATIVES FROM THE CULTURE BROTH OF FUNGI PHELLINUS AND INONOTUS SPP

A composition containing hispidin derivatives isolated from the culture broth of fungi Phellinus and Inonotus spp. is provided to scavenge superoxide radical, ABTS(2,2'-azinobis-(3-ethylbenzothiazoline-6-sulphonic acid)) radical and DPPH(1,1-Diphenyl-2-Picrylhydrazyl) radical, so that the composition is useful for….

OncologyCognition & nervesMetabolic healthGut & microbiome

Shiitake · 2019 · Review · Toxicon: official journal of the International Society on Toxinology

Mushroom poisoning: A proposed new clinical classification.

Mushroom poisoning is a significant and increasing form of toxin-induced-disease. Existing classifications of mushroom poisoning do not include more recently described new syndromes of mushroom poisoning and this can impede the diagnostic process..

Lion's Mane · 2012 · Journal Article · Journal of Japan Society of Civil Engineers, Ser. G (Environmental Research)

IDENTIFICATION OF ODOR SUBSTANCES IN YAMABUSHITAKE MUSHROOM (Hericium erinaceum) CULTURE MEDIA CONTAINING 'SHOCHU' LEES AND STARCH WASTES, AND BASIC STUDIES ON THEIR DISAPPEARANCE

Metadata-grounded summary: This journal article indexes research on Hericium erinaceus in Journal of Japan Society of Civil Engineers, Ser. G (Environmental Research) in 2012.

Immune supportCognition & nervesEnergy & fatigueMetabolic health

Cordyceps · 2007 · Journal Article · Biological and Pharmaceutical Bulletin

Antidepressant-Like Effect of Cordyceps sinensis in the Mouse Tail Suspension Test

Cordyceps sinensis (CS) has been known as a component of traditional medicines that elicit various biological effects such as anti-fatigue, immunomodulatory, and hypoglycemic actions..

OncologyCognition & nervesEnergy & fatigue

Lion's Mane · 2020 · Research Article · Antioxidants (Basel, Switzerland)

Post-Treatment with Erinacine A, a Derived Diterpenoid of H. erinaceus, Attenuates Neurotoxicity in MPTP Model of Parkinson's Disease.

Hericium erinaceus, a valuable pharmaceutical and edible mushroom, contains potent bioactive compounds such as H. erinaceus mycelium (HEM) and its derived ethanol extraction of erinacine A, which have been found to regulate physiological functions in our previous study..

Maitake · 2020 · Journal Article · International journal of medicinal mushrooms

Quantification of β-Glucan from Culinary-Medicinal Mushrooms Using Novel Artificial β-Glucan Recognition Protein.

(1->3)-β-D-glucans (BGs), found in culinary-medicinal mushrooms, exhibit an immunostimulatory effect; hence, it is important to measure the content of BGs contained in mushrooms..

OncologyImmune supportCognition & nervesEnergy & fatigue

Lion's Mane · 2019 · Research Article · Molecules (Basel, Switzerland)

Anti-Inflammatory Effect of Erinacine C on NO Production Through Down-Regulation of NF-κB and Activation of Nrf2-Mediated HO-1 in BV2 Microglial Cells Treated with LPS.

Previous studies have revealed the anti-inflammatory and neuroprotective properties of Hericium erinaceus extracts, including the fact that the active ingredient erinacine C (EC) can induce the synthesis of nerve growth factor..

Turkey Tail · 2019 · Journal Article · Environmental pollution (Barking, Essex: 1987)

Fungal biodegradation of the N-nitrosodimethylamine precursors venlafaxine and O-desmethylvenlafaxine in water.

Antidepressant drugs such as Venlafaxine (VFX) and O-desmethylvenlafaxine (ODMVFX) are emerging contaminants that are commonly detected in aquatic environments, since conventional wastewater treatment plants are unable to completely remove them..

Immune supportCognition & nervesGut & microbiome

Maitake · 2019 · Research Article · Food & function

Macrophage activation by edible mushrooms is due to the collaborative interaction of toll-like receptor agonists and dectin-1b activating beta glucans derived from colonizing microorganisms.

Research supports the theory that the microbiome of plants and mushrooms produce potent activators of pathogen recognition receptors which are principal contributors to the stimulation of macrophages..

Shiitake · 2018 · Journal Article · Journal of evidence-based integrative medicine

Effects of AHCC® on Immune and Stress Responses in Healthy Individuals.

AHCC® is a functional food from the basidiomycete Lentinula edodes. We evaluated the effects of AHCC® on subjects under different kinds of stress and at rest.

Turkey Tail · 2018 · Journal Article · Journal of microbiology and biotechnology

Laccase Fermentation of Clove Extract Increases Content of Dehydrodieugenol, Which Has Neuroprotective Activity against Glutamate Toxicity in HT22 Cells.

Enzyme fermentation is a type of food processing technique generally used to improve the biological activities of food and herbal medicines. In this study, a Syzygii Flos (clove) extract was fermented using laccase derived from Trametes versicolor (LTV)..