MycoData

Turkey Tail · 2014 · Research Support, Non U.S. Gov'T · The Science of the total environment

Hospital wastewater treatment by fungal bioreactor: removal efficiency for pharmaceuticals and endocrine disruptor compounds.

Hospital effluents contribute to the occurrence of emerging contaminants in the environment due to their high load of pharmaceutical active compounds (PhACs) and some endocrine disruptor compounds (EDCs)..

Turkey Tail · 2014 · Research Support, Non U.S. Gov'T · Applied biochemistry and biotechnology

Immobilized laccase on activated poly(vinyl alcohol) microspheres for enzyme thermistor application.

Poly(vinyl alcohol) (PVA) microspheres were prepared by inverse suspension crosslinked method, with glutaraldehyde as a crosslinking agent. PVA microspheres activated with aldehyde groups were employed for Trametes versicolor laccase immobilization..

Agarikon · 2014 · Research Support, Non U.S. Gov'T · Molecules (Basel, Switzerland)

In vivo and in vitro anti-tumor effects of fungal extracts.

Fungal extracts are extensively used as nutritional supplements in Far-Eastern Asia. In this study, we aimed to evaluate the anti-cancer activities of some different fungal species against different cancer cell lines.

Oncology

Turkey Tail · 2014 · Dissertation · journal metadata

Investigating the role of laccase and laccase mediator systems to improve the saccharification of biomass for bioethanol production

Metadata-grounded summary: This dissertation indexes research on Trametes versicolor in 2014. MycoData maps the paper to oncology, immune support based on its title, species context, article metadata, and study classification..

Turkey Tail · 2014 · Research Support, Non U.S. Gov'T · ChemSusChem

Laccase-mediator system for alcohol oxidation to carbonyls or carboxylic acids: toward a sustainable synthesis of profens.

By combining two green and efficient catalysts, such as the commercially available enzyme laccase from Trametes versicolor and the stable free radical 2,2,6,6-tetramethylpiperidine-N-oxyl (TEMPO), the oxidation in water of some primary alcohols to the corresponding carboxylic acids or aldehydes and of selected….

Turkey Tail · 2014 · Research Support, U.S. Gov'T, Non P.H.S. · Environmental pollution (Barking, Essex: 1987)

Oxidative enzymatic response of white-rot fungi to single-walled carbon nanotubes.

Although carbon nanomaterials such as single-walled carbon nanotubes (SWCNT) are becoming increasingly prevalent in manufacturing, there is little knowledge on the environmental fate of these materials..

Turkey Tail · 2014 · Research Support, Non U.S. Gov'T · Journal of hazardous materials

Potential of fungal co-culturing for accelerated biodegradation of petroleum hydrocarbons in soil.

The potential of fungal co-culture of the filamentous Pestalotiopsis sp. NG007 with four different basidiomycetes--Trametes versicolor U97, Pleurotus ostreatus PL1, Cerena sp.

Maitake · 2014 · Research Support, Non U.S. Gov'T · Carbohydrate polymers

Protective effect of polysaccharides on simulated microgravity-induced functional inhibition of human NK cells.

Polysaccharides are believed to be strong immunostimulants that can promote the proliferation and activity of T cells, B cells, macrophages and natural killer (NK) cells. This study aimed to investigate the effects of five polysaccharides (Grifola frondosa polysaccharide (GFP), lentinan (LNT), G..

Energy & fatigueGut & microbiome

Turkey Tail · 2014 · Research Support, Non U.S. Gov'T · Bioresource technology

Re-inoculation strategies enhance the degradation of emerging pollutants in fungal bioaugmentation of sewage sludge.

The use of Trametes versicolor has been partially successful in the removal of some pharmaceuticals from sewage sludge in laboratory-scale biopile systems. The application of two strategies for the re-inoculation of biomass was assessed during the fungal bioaugmentation of non-sterile sludge (42-d treatment) as an….

Liver supportSkin & hydration

Lion's Mane · 2014 · Research Support, Non U.S. Gov'T · International journal of medicinal mushrooms

Screening and isolation for anti-hepatofibrotic components from medicinal mushrooms using TGF-(β1-induced live fibrosis in hepatic stellate cells.

Liver fibrosis is a wound-healing response to chronic liver injury that could lead to liver failure, but treatment remains ineffective. In this study, we investigated anti-hepatic fibrosis activity of n-hexane, chloroform, ethyl acetate, and methanol extracts of mycelia from six commercially available medicinal….

Maitake · 2014 · Research Support, Non U.S. Gov'T · Amino acids

The functional role of Cys3-Cys4 loop in hydrophobin HGFI.

Hydrophobins are a large group of low-molecular weight proteins. These proteins are highly surface-active and can form amphipathic membranes by self-assembling at hydrophobic-hydrophilic interfaces.

OncologyImmune supportSkin & hydration

Snow Fungus · 2014 · Evaluation Study · International journal of medicinal mushrooms

The optimum submerged culture condition of the culinary-medicinal white jelly mushroom (Tremellomycetes) and its antioxidant properties.

Tremella fuciformis is a natural edible and medicinal mushroom commercially available in Taiwan. In this study, the effects of initial pH, incubation time, and various media to optimize exopolysaccharide (EPS) production by T.

OncologyCognition & nervesEnergy & fatigueMetabolic health

Mesima · 2014 · Research Support, Non U.S. Gov'T · Experimental cell research

The protective effect of hispidin against hydrogen peroxide-induced apoptosis in H9c2 cardiomyoblast cells through Akt/GSK-3β and ERK1/2 signaling pathway.

Hispidin, a phenolic compound from Phellinus linteus (a medicinal mushroom), has been shown to possess strong anti-oxidant, anti-cancer, anti-diabetic, and anti-dementia properties. However, the cardioprotective efficacy of hispidin has not yet been investigated..

Niu-Chang-Chih · 2014 · Research Support, Non U.S. Gov'T · The Journal of organic chemistry

Total synthesis of (±)-antroquinonol d.

Total synthesis of (±)-antroquinonol D, which is isolated from very expensive and rarely found Antrodia camphorata and which has potential anticancer properties, was achieved from 4-methoxyphenol. In addition, a Michael addition to dimethoxy cyclohexadienones was studied..

Oncology

Maitake · 2013 · Research Support, Non U.S. Gov'T · Carbohydrate polymers

A chemically sulfated polysaccharide from Grifola frondos induces HepG2 cell apoptosis by notch1-NF-κB pathway.

Sulfated polysaccharides have been known to inhibit proliferation in tumor cells. However, the molecular mechanisms involved in sulfated polysaccharides-induced apoptosis are still uncharacterized..

Zhu Ling · 2013 · Research Support, Non U.S. Gov'T · Applied spectroscopy

A sensitive spectrofluorometric method for determination of ergosta-4,6,8(14),22-tetraen-3-one in rat plasma, feces, and urine for application to pharmacokinetic studies using cerium(III) as a probe.

Ergosta-4,6,8(14),22-tetraen-3-one (ergone) isolated from Polyporus umbellatus possesses a variety of pharmacological activities in vivo and in vitro, including cytotoxic, diuretic, and immunosuppressive effect..

Immune supportEnergy & fatigue

Niu-Chang-Chih · 2013 · Research Support, Non U.S. Gov'T · Free radical biology & medicine

Antroquinonol mitigates an accelerated and progressive IgA nephropathy model in mice by activating the Nrf2 pathway and inhibiting T cells and NLRP3 inflammasome.

High levels of reactive oxygen species (ROS), systemic T cell activation, and macrophage infiltration in the kidney are implicated in the acceleration and progression of IgA nephropathy (IgAN), the most frequent type of primary glomerulonephritis..

Turkey Tail · 2013 · Research Support, Non U.S. Gov'T · Bioresource technology

Bacterial-fungal interactions enhance power generation in microbial fuel cells and drive dye decolourisation by an ex situ and in situ electro-Fenton process.

In this work, the potential for sustainable energy production from wastes has been exploited using a combination fungus-bacterium in microbial fuel cell (MFC) and electro-Fenton technology..

Immune supportGut & microbiome

Enoki · 2013 · Comparative Study · International immunopharmacology

Biochemical and functional characterization of recombinant fungal immunomodulatory proteins (rFIPs).

In this study, two novel FIPs have been identified and characterized. The first is FIP-nha, identified in the ascomycete Nectria haematococca, and as such, FIP-nha would be the first FIP to be identified outside the order of Basidiomycota.

Energy & fatigueGut & microbiome

Turkey Tail · 2013 · Comparative Study · Journal of hazardous materials

Comparative assessment of bioremediation approaches to highly recalcitrant PAH degradation in a real industrial polluted soil.

High recalcitrant characteristics and low bioavailability rates due to aging processes can hinder high molecular weight polycyclic aromatic hydrocarbons (HMW-PAHs) bioremediation in real industrial polluted soils..

Turkey Tail · 2013 · Comparative Study · Environmental technology

Comparative assessment of three ligninolytic fungi for removal of phenolic endocrine disruptors from freshwaters and sediments.

Bisphenol A (BPA) and 4-n-nonylphenol (NP) are two endocrine disruptor compounds dangerous to animals, especially aquatics, and humans. They can be leached from urban and industrial wastes and contaminate the environment..

Turkey Tail · 2013 · Comparative Study · Journal of bioscience and bioengineering

Comparison of laccase production levels in Pichia pastoris and Cryptococcus sp. S-2.

The heterologous expression of the laccase gene from Trametes versicolor and Gaeumannomyces graminis was evaluated in the yeasts Pichia pastoris and Cryptococcus sp. S-2.

Turkey Tail · 2013 · Research Support, Non U.S. Gov'T · Human & experimental toxicology

Cytotoxic, genotoxic and antigenotoxic potencies of oligorutins.

Rutin has been enzymatically oligomerized by laccase from Trametes versicolor. Five fractions of oligomers were obtained from the monomers having high solubility in water, which can reach 351-times that of rutin.

Oncology

Wood Ear · 2013 · Comparative Study · Bioresource technology

Detection of feruloyl- and cinnamoyl esterases from basidiomycetes in the presence of interfering laccase.

Little is known on basidiomycete sources of feruloyl esterases (FAEs), although many wood-rotting representatives of these fungi typically grow on feruloyl-rich substrates. A major reason is that the almost ubiquitous presence of laccases interferes with the detection of FAE activity..

Turkey Tail · 2013 · Research Support, Non U.S. Gov'T · Bioresource technology

Development and optimization of single and combined detoxification processes to improve the fermentability of lignocellulose hydrolyzates.

In this work, an enzyme catalyzed detoxification process of lignocellulose hydrolyzates with immobilized laccase from Trametes versicolor was developed and optimized..

Wood Ear · 2013 · Research Support, Non U.S. Gov'T · The journal of physical chemistry. B

Effect of heating on chain conformation of branched β-glucan in water.

The thermal stability of polysaccharides under heat treatment is an important factor to their functionality in food and pharmaceutical fields. The stiff branched β-glucan coded as AF1-1 isolated from Auricularia auricula-judae was investigated with viscometry, dynamic light scattering (DLS), and size-exclusion….

Immune support

Immune supportRespiratory

Enoki · 2013 · Research Support, Non U.S. Gov'T · Cytokine

Effect of the fungal immunomodulatory protein FIP-fve on airway inflammation and cytokine production in mouse asthma model.

The allergy is dependent on the balance between Th1 and Th2. The fungal immunodulatory protein (FIP-fve) was isolated from Flammulina velutipes.

Turkey Tail · 2013 · Research Support, Non U.S. Gov'T · Chemical communications (Cambridge, England)

Efficient direct oxygen reduction by laccases attached and oriented on pyrene-functionalized polypyrrole/carbon nanotube electrodes.

We report the functionalization of multi-walled carbon nanotube (MWCNT) electrodes by oxidative electropolymerization of pyrrole monomers bearing pyrene and N-hydroxysuccinimide groups..

Enoki · 2013 · Comparative Study · TheScientificWorldJournal

Fatty acid compositions of six wild edible mushroom species.

The fatty acids of six wild edible mushroom species (Boletus reticulatus, Flammulina velutipes var. velutipes, Lactarius salmonicolor, Pleurotus ostreatus, Polyporus squamosus, and Russula anthracina) collected from different regions from Anatolia were determined..

Wood Ear · 2013 · Research Support, Non U.S. Gov'T · The Journal of biological chemistry

First crystal structure of a fungal high-redox potential dye-decolorizing peroxidase: substrate interaction sites and long-range electron transfer.

Dye-decolorizing peroxidases (DyPs) belong to the large group of heme peroxidases. They utilize hydrogen peroxide to catalyze oxidations of various organic compounds.

Turkey Tail · 2013 · Research Support, Non U.S. Gov'T · Applied biochemistry and biotechnology

Functional magnetic mesoporous nanoparticles for efficient purification of laccase from fermentation broth in magnetically stabilized fluidized bed.

A magnetically stabilized fluidized bed (MSFB) with the Cu(2+)-chelated magnetic mesoporous silica nanoparticles (MMSNPs-Cu(2+)) was established to purify laccase directly from the fermentation broth of Trametes versicolor..

Turkey Tail · 2013 · Research Support, Non U.S. Gov'T · Journal of hazardous materials

Fungal permeable reactive barrier to remediate groundwater in an artificial aquifer.

Biobarriers, as permeable reactive barriers (PRBs), are a common technology that mainly uses bacteria to remediate groundwater in polluted aquifers. In this study, we propose to use Trametes versicolor, a white-rot fungus, as the reactive element because of its capacity to degrade a wide variety of highly recalcitrant….

Metabolic health

Immune supportGut & microbiome

Enoki · 2013 · Research Support, Non U.S. Gov'T · Applied microbiology and biotechnology

In vitro rapid evolution of fungal immunomodulatory proteins by DNA family shuffling.

Fungal immunomodulatory proteins (FIPs) found in a wide variety of mushrooms hold significant therapeutic potential. Despite much research, the structural determinants for their immunomodulatory functions remain unknown..

Zhu Ling · 2013 · Research Support, Non U.S. Gov'T · Journal of cosmetic science

Inhibitory effects of Korean indigenous plants on tyrosinase and melanogenesis.

To search for new depigmenting cosmetic ingredients from Korean herbal extracts of traditional Korean medicines (TKMs), we screened about 17 TKM extracts collected in the Republic of Korea..

OncologySkin & hydration

Maitake · 2013 · Research Support, Non U.S. Gov'T · Food & function

Inhibitory effects of medicinal mushrooms on α-amylase and α-glucosidase - enzymes related to hyperglycemia.

In Asia, medicinal mushrooms have been popularly used as folk medicine and functional foods. In this study, our aim was to examine the inhibitory effects of six medicinal mushrooms on key enzymes (α-amylase and α-glucosidase) related to hyperglycemia; chemical profiles of bioactive extracts were also examined..

Metabolic health

Turkey Tail · 2013 · Research Support, Non U.S. Gov'T · Analytical chemistry

Label-free fluorometric method for monitoring conformational flexibility of laccase based on a selective laccase sensor.

A facile and selective fluorescence sensor for laccase determination has been proposed depending on the interaction between 3-azidocoumarin and trametes versicolor (Tv) laccase in this paper..

Turkey Tail · 2013 · Research Support, Non U.S. Gov'T · Water science and technology: a journal of the International Association on Water Pollution Research

Laccase immobilized onto poly(GMA-MAA) microspheres for p-benzenediol removal from wastewater.

Enzymes have already been extensively applied to degrade various organic pollutants in industrial wastewater, and how to improve the stability and reusability of the enzymes is critical to their practical application..

OncologyImmune supportCognition & nerves

Maitake · 2013 · Research Support, Non U.S. Gov'T · BMC complementary and alternative medicine

Neurite outgrowth stimulatory effects of culinary-medicinal mushrooms and their toxicity assessment using differentiating Neuro-2a and embryonic fibroblast BALB/3T3.

BACKGROUND: Mushrooms are not only regarded as gourmet cuisine but also as therapeutic agent to promote cognition health. However, little toxicological information is available regarding their safety..

Maitake · 2013 · Research Support, Non U.S. Gov'T · Colloids and surfaces. B, Biointerfaces

Poly(ε-caprolactone) modified with fusion protein containing self-assembled hydrophobin and functional peptide for selective capture of human blood outgrowth endothelial cells.

Human blood outgrowth endothelial cells (HBOECs)-specific binding peptide, TPSLEQRTVYAK (TPS), was proposed to be applied on autologous cell therapy for treating cardiovascular diseases..

OncologyImmune supportCognition & nervesEnergy & fatigue

Maitake · 2013 · Research Support, Non U.S. Gov'T · BMC complementary and alternative medicine

Potentiation of neuritogenic activity of medicinal mushrooms in rat pheochromocytoma cells.

BACKGROUND: Senescence of the neurons is believed to be a focal factor in the development of age-related neurodegenerative diseases such as Alzheimer's disease. Diminutions in the levels of nerve growth factor (NGF) lead to major declines in brain cell performance..

Lion's Mane · 2013 · Research Support, Non U.S. Gov'T · Food chemistry

Quality of bread supplemented with mushroom mycelia.

Mushroom mycelia of Antrodia camphorata, Agaricus blazei, Hericium erinaceus and Phellinus linteus were used to substitute 5% of wheat flour to make bread. Bread quality, including specific volume, colour property, equivalent umami concentration (EUC), texture profile analysis, sensory evaluation and functional….

Enoki · 2013 · Research Support, Non U.S. Gov'T · Plant physiology

Reduction of oxalate levels in tomato fruit and consequent metabolic remodeling following overexpression of a fungal oxalate decarboxylase.

The plant metabolite oxalic acid is increasingly recognized as a food toxin with negative effects on human nutrition. Decarboxylative degradation of oxalic acid is catalyzed, in a substrate-specific reaction, by oxalate decarboxylase (OXDC), forming formic acid and carbon dioxide..

Metabolic health

Turkey Tail · 2013 · Research Support, Non U.S. Gov'T · Applied biochemistry and biotechnology

Refolding of laccase in dilution additive mode with copper-based ionic liquid.

Ionic liquids (ILs) are molten salts which do not crystallize at room temperature. Tunable physicochemical properties of ILs including hydrophobicity and polarity facilitate their applications in many biological processes..

Wood Ear · 2013 · Research Support, Non U.S. Gov'T · Chemosphere

Solid state fermentation of olive mill residues by wood- and dung-dwelling Agaricomycetes: effects on peroxidase production, biomass development and phenol phytotoxicity.

The in vivo conversion of dry olive mill residue (DOR) by wood- and dung-dwelling fungi - Auricularia auricula-judae, Bjerkandera adusta and Coprinellus radians - increases peroxidase secretion up to 3.2-3.5-fold (∼1.3, 3.5 and 7.0 Ug(-1) DOR for dye-decolorizing peroxidase, manganese peroxidase and aromatic….

Wood Ear · 2013 · Comparative Study · Applied microbiology and biotechnology

Substrate oxidation by dye-decolorizing peroxidases (DyPs) from wood- and litter-degrading agaricomycetes compared to other fungal and plant heme-peroxidases.

Catalytic and physicochemical properties of representative fungal dye-decolorizing peroxidases (DyPs) of wood- (WRF) and litter-decomposing white-rot fungi (LDF) are summarized and compared, including one recombinant Mycetinis scorodonius DyP (rMscDyP; LDF), the wild-type Auricularia auricula-judae DyP (AauDyP; WRF),….

Cognition & nervesEnergy & fatigueMetabolic health

Zhu Ling · 2013 · Research Support, Non U.S. Gov'T · Chemico-biological interactions

UPLC-Q-TOF/HSMS/MS(E)-based metabonomics for adenine-induced changes in metabolic profiles of rat faeces and intervention effects of ergosta-4,6,8(14),22-tetraen-3-one.

Ergosta-4,6,8(14),22-tetraen-3-one (ergone), isolated from the medicinal fungus Polyporus umbellatus, has been proven to prevent the progression of renal injury and the subsequent renal fibrosis..

Enoki · 2013 · Research Support, Non U.S. Gov'T · Brazilian journal of microbiology: [publication of the Brazilian Society for Microbiology]

Use of P450 cytochrome inhibitors in studies of enokipodin biosynthesis.

Enokipodins A, B, C, and D are antimicrobial sesquiterpenes isolated from the mycelial culture medium of Flammulina velutipes, an edible mushroom. The presence of a quaternary carbon stereocenter on the cyclopentane ring makes enokipodins A-D attractive synthetic targets..

Turkey Tail · 2012 · English Abstract · Huan jing ke xue= Huanjing kexue

[Immobilization of crude laccase onto anion exchange resin and its application in decoloration of malachite green].

Crude laccase from Trametes versicolor was immobilized onto anion exchange resin D201 by three methods, i.e., direct electrostatic adsorption (D201-Lac-I), crosslinking after electrostatic adsorption (D201-Lac-II) and electrostatic adsorption after treating D201 with glutaraldehyde (D201-Lac-III)..