MycoData

Immune supportEnergy & fatigue

Mesima · 2006 · Research Support, Non U.S. Gov'T · Journal of ethnopharmacology

Heme oxygenase-1 mediates the anti-inflammatory effect of mushroom Phellinus linteus in LPS-stimulated RAW264.7 macrophages.

This work aimed to elucidate the anti-inflammatory mechanism of the n-BuOH subfraction (PL) prepared from fruiting bodies of Phellinus linteus. PL induced heme oxygenase-1 (HO-1) of the RAW264.7 macrophages in concentration- and time-dependent manner..

Immune supportEnergy & fatigueMetabolic health

Niu-Chang-Chih · 2006 · Research Support, Non U.S. Gov'T · International journal of food microbiology

Promotion of hyphal growth and underlying chemical changes in Antrodia camphorata by host factors from Cinnamomum camphora.

The aim of this research was to investigate the hyphal growth-promoting factors (HGFs) of Antrodia camphorata from the host-related species, Cinnamomum camphora (CC) and the underlying chemical produced..

Turkey Tail · 2026 · Journal Article · Environmental technology

Enhanced soil remediation of benzo[a]pyrene using combined white-rot fungus and plants: promoting substrate competition and community succession.

Microbe-assisted phytoremediation is emerging as one of the most effective methods for degrading organic contaminants in soils through the interaction of plants and their associated rhizosphere microbes. However, the mechanisms behind plant-microbe interactions remain ambiguous..

Reishi · 2026 · Journal Article · Microbiology spectrum

Integrative analysis of metabolome and transcriptome reveals new insights into the formation and regulation of major components of G. leucocontextum and G. lucidum.

UNLABELLED: Ganoderma is a class of medicinal fungi with diverse medicinal effects, of which triterpenoids are one of the main pharmacologically active substances..

OncologyImmune supportCognition & nervesEnergy & fatigue

Reishi · 2026 · Journal Article · Journal of ethnopharmacology

Lucidenic acid A drives PI3K/AKT/BDNF signaling to improve memory impairment in mice and alleviate cellular nerve damage.

ETHNOPHARMACOLOGICAL RELEVANCE: Enhancing memory and alleviating amnesia are among the conditions that Ganoderma lucidum has historically been used to treat. However, there are relatively few studies on the potential therapeutic effects of active ingredients derived from Ganoderma lucidum in the treatment of memory….

Turkey Tail · 2025 · Research Article · Polymers

Artificial Neural Network Prediction of Mechanical Properties in Mycelium-Based Biocomposites.

Mycelium-based biocomposites (MBBs) represent a sustainable alternative to synthetic composites, as they are produced from lignocellulosic substrates bonded by fungal mycelium..

Reishi · 2025 · Journal Article · World J Microbiol Biotechnol

Preparation of fungal biocomposite for environment friendly packaging of plant saplings

Plastic packaging poses significant environmental and health risks due to its non-degradability and its accumulation as microplastics in soil, plants, and food chains. Fungal biocomposites derived from lignocellulosic biomass offer a sustainable alternative for biodegradable packaging..

Reishi · 2025 · Journal Article · World journal of microbiology & biotechnology

Preparation of fungal biocomposite for environment friendly packaging of plant saplings.

Reishi · 2025 · Research Article · Biomimetics (Basel, Switzerland)

The Effects of the Substrate Length and Cultivation Time on the Physical and Mechanical Properties of Mycelium-Based Cushioning Materials from Salix psammophila and Peanut Straw.

Mycelium-based biocomposites represent a novel class of environmentally friendly materials. This study investigated the potential of using Salix psammophila and peanut straw as substrates for cultivating Pleurotus ostreatus and Ganoderma lucidum, respectively, to fabricate mycelium-based cushioning materials..

Energy & fatigueGut & microbiomeLiver supportSkin & hydration

Shiitake · 2024 · Research Article · American journal of physiology. Gastrointestinal and liver physiology

AHCC inhibited hepatic stellate cells activation by regulation of cytoglobin induction via TLR2-SAPK/JNK pathway and collagen production via TLR4-NF-κβ pathway.

Cirrhosis, which represents the end stage of liver fibrosis, remains a life-threatening condition without effective treatment. Therefore, prevention of the progression of liver fibrosis through lifestyle habits such as diet and exercise is crucial..

Energy & fatigueMetabolic healthGut & microbiome

Oyster Mushroom · 2024 · Journal Article · Animal feed science and technology

Effect of mushroom crop residue on growth performance, carcass traits, nutrient digestibility, nitrogen balance, ingestive behavior, ruminal and blood parameters of lambs

Using agricultural wastes as substrates of mushroom cultivation can minimize environmental pollution and provide a high-quality substrate that might be used for animal feeding after cultivation, which is beneficial for ruminants..

Immune supportEnergy & fatigueGut & microbiomeSkin & hydration

Reishi · 2024 · Research Article · Bioresources and bioprocessing

Evaluation of cosmetic efficacy of lychee seed fermentation liquid.

BACKGROUND: Lychee seeds were fermented by three kinds of bacteria (Lactobacillus plantarum, Saccharomyces cerevillus and ganoderma lucidum mycelium), and two effective strains were selected by two indexes of activity content and antioxidant, so as to further verify whether lychee seeds have waste multiplication….

Immune supportEnergy & fatigueSkin & hydration

Lion's Mane · 2024 · Research Article · Foods (Basel, Switzerland)

Mitigating Oxidative Stress and Promoting Cellular Longevity with Mushroom Extracts.

Oxidative stress can disrupt the body's ability to fight harmful free radicals, leading to premature aging and various health complications. This study investigated the antioxidant and anti-aging properties of four medicinal and edible mushrooms: Ganoderma lucidum, Hericium erinaceus, Pleurotus ostreatus, and Agaricus….

Turkey Tail · 2024 · Research Article · International journal of molecular sciences

Ultra-Pressurized Deposition of Hydrophobic Chitosan Surface Coating on Wood for Fungal Resistance.

Fungi (Neolentinus lepideus, Nl, and Trametes versicolor, Tv) impart wood rot, leading to economic and environmental issues. To overcome this issue, toxic chemicals are commonly employed for wood preservation, impacting the environment and human health..

Reishi · 2023 · Research Support, Non U.S. Gov'T · Fungal genetics and biology: FG & B

Comparative proteomic analysis of two divergent strains provides insights into thermotolerance mechanisms of Ganoderma lingzhi.

Heat stress (HS) is a major abiotic factor influencing fungal growth and metabolism. However, the genetic basis of thermotolerance in Ganoderma lingzhi (G.

Immune supportEnergy & fatigueLiver supportRespiratory

Reishi · 2023 · Research Support, Non U.S. Gov'T · Scientific reports

Immuno-physiological effects of dietary reishi mushroom powder as a source of beta-glucan on Rohu, Labeo rohita challenged with Aeromonas veronii.

Beta-glucans have immense potential to stimulate immune modulation in fish by being injected intramuscularly, supplemented with feed or immersion routes of administration. We studied how supplementing Labeo rohita's diet with reishi mushroom powder containing beta-glucan influenced immunological function..

Energy & fatigueMetabolic health

Cordyceps · 2023 · Research Support, Non U.S. Gov'T · Scientific reports

Transcriptome and metabonomics combined analysis revealed the energy supply mechanism involved in fruiting body initiation in Chinese cordyceps.

Chinese cordyceps was one of most valuable traditional Chinese medicine fungi. To elucidate the molecular mechanisms related to energy supply mechanism involved in the initiation and formation of primordium in Chinese cordyceps, we performed the integrated metabolomic and transcriptomic analyses of it at….

Immune supportCognition & nervesEnergy & fatigue

Nameko · 2022 · Research Support, Non U.S. Gov'T · Journal of food biochemistry

Chemical properties and anti-fatigue effect of polysaccharide from Pholiota nameko.

The aim of this study was to explore the primary chemical properties and anti-fatigue effect in vivo of Pholiota nameko polysaccharide (PNP). Through UV-visible spectrum, the absorption peaks of proteins, nucleic acids and pigments were not found..

Energy & fatigueMetabolic healthGut & microbiomeLiver support

Cordyceps · 2022 · Research Support, Non U.S. Gov'T · Scientific reports

Cordyceps inhibits ceramide biosynthesis and improves insulin resistance and hepatic steatosis.

Ectopic ceramide accumulation in insulin-responsive tissues contributes to the development of obesity and impairs insulin sensitivity. Moreover, pharmacological inhibition of serine palmitoyl transferase (SPT), the first enzyme essential for ceramide biosynthesis using myriocin in rodents reduces body weight and….

Immune supportEnergy & fatigue

Shiitake · 2021 · Evaluation Study · Journal of the science of food and agriculture

Intensive pulsed light pretreatment combined with controlled temperature and humidity for convection drying to reduce browning and improve quality of dried shiitake mushrooms.

BACKGROUND: The change of surface color caused by browning during the drying process of shiitake mushrooms seriously affects its market circulation. Intensive pulsed light (IPL) as a non-heat-treatment method can reduce enzyme activity by changing the enzyme structure..

OncologyImmune supportCognition & nervesEnergy & fatigue

Cordyceps · 2026 · Review · Die Naturwissenschaften

Research advances on Cordyceps sinensis and its components in relation to omics biomarkers for the neurological disorders.

Cordyceps is a traditional medicinal fungus belonging to the species Ophiocordyceps sinensis. It grows in the alpine ecological zone of the Tibetan Plateau and exhibits dual characteristics of both insects and fungi.

Turkey Tail · 2023 · Research Article · Polymers

Fungal Selectivity and Biodegradation Effects by White and Brown Rot Fungi for Wood Biomass Pretreatment.

The biodegradation path and mechanism of wood varies depending on diverse fungi and tree species, as fungi possess selectivity in degradation of versatile wood components..

Reishi · 2023 · Journal Article · Environmental science and pollution research international

Nutrient removal from biogas slurry and biogas upgrading by microalgae-fungi-bacteria co-cultivation under different carbon nanotubes concentration.

In this study, Chlorella vulgaris, Ganoderma lucidum, and endophytic bacteria were co-cultivated with the stimulation of strigolactone analogs GR24 to prepare pellets..

King Oyster · 2022 · Journal Article · Journal of the science of food and agriculture

Improving the nutritional value and digestibility of wheat straw, rice straw, and corn cob through solid state fermentation using different Pleurotus species

BACKGROUND: The growing food‐feed‐fuel competition, declining availability of traditional feeds, higher prices, and the urgent need to provide long‐term sustainability for animal production have all triggered global research into the optimum extraction of energy and nutrients from lignin‐rich plant biomass..

King Oyster · 2022 · Journal Article · Journal of the science of food and agriculture

Improving the nutritional value and digestibility of wheat straw, rice straw, and corn cob through solid state fermentation using different Pleurotus species.

BACKGROUND: The growing food-feed-fuel competition, declining availability of traditional feeds, higher prices, and the urgent need to provide long-term sustainability for animal production have all triggered global research into the optimum extraction of energy and nutrients from lignin-rich plant biomass..

Reishi · 2022 · Journal Article · Bioresource technology

Performance of different microalgae-fungi-bacteria co-culture technologies in photosynthetic and removal performance in response to various GR24 concentrations.

The purification effect of two different microalgae-fungi-bacteria symbiosis technologies on biogas and biogas slurry was studied to determine the best symbiosis treatment technology and the suitable concentration of GR24..

Shiitake · 2021 · Research Article · Molecules (Basel, Switzerland)

Sunlight Photocatalytic Performance of ZnO Nanoparticles Synthesized by Green Chemistry Using Different Botanical Extracts and Zinc Acetate as a Precursor.

In this work, the assessment of Azadirachta indica, Tagetes erecta, Chrysanthemum morifolium, and Lentinula edodes extracts as catalysts for the green synthesis of zinc oxide nanoparticles (ZnO NPs) was performed..

Immune supportEnergy & fatigueMetabolic health

Lion's Mane · 2020 · Journal Article · International journal of biological macromolecules

A novel Hericium erinaceus polysaccharide: Structural characterization and prevention of H2O2-induced oxidative damage in GES-1 cells.

In this paper, the structural characteristics and bioactivity of a novel polysaccharide from H. erinaceus (HEPN) were investigated, wherein, physico-chemical characterization demonstrated that HEPN with an average molecular weight of 12.713 kDa was composed of mannose (5.13%), glucose (43.02%), and galactose (51.85%)..

OncologyImmune supportEnergy & fatigueMetabolic health

Reishi · 2020 · Journal Article · Biological and Pharmaceutical Bulletin

Amelioration of the Lipogenesis, Oxidative Stress and Apoptosis of Hepatocytes by a Novel Proteoglycan from Ganoderma lucidum

The steatosis and resultant oxidative stress and apoptosis play the important roles in the progression of nonalcoholic fatty liver disease (NAFLD), therefore, searching for the effective drugs against NAFLD has been a hot topic..

Energy & fatigueRespiratory

Cordyceps · 2020 · Journal Article · Science China. Life sciences

Developmental recording of the ghost-moth larvae after ex situ infection by Ophiocordyceps sinensis.

Metadata-grounded summary: This journal article indexes research on Ophiocordyceps sinensis in Science China. Life sciences in 2020.

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

Enoki · 2020 · Research Article · Animals: an open access journal from MDPI

Dietary Supplementation with Flammulina velutipes Stem Waste on Growth Performance, Fecal Short Chain Fatty Acids and Serum Profile in Weaned Piglets.

This study was conducted to evaluate the effects of dietary FVS supplementation on growth performance, nutrient digestibility, biochemical profile of serum and fecal short chain fatty acids (SCFAs) production in weaned piglets..

Cordyceps · 2019 · Research Article · Mitochondrial DNA. Part B, Resources

Complete mitochondrial genome of Tolypocladium sp. YFCC 1805002 isolated from Ophiocordyceps sinensis in Baima Snow Mountain, Southwestern China.

Tolypocladium sp. YFCC 1805002, an undescribed species isolated from natural Ophiocordyces sinensis in Baima Snow Mountain, Deqin County of Yunnan in Southwestern China, was sequenced on the Illumina sequencing platform..

OncologyImmune supportEnergy & fatigue

Shiitake · 2019 · Journal Article · Carbohydrate polymers

Selenium-containing polysaccharides from Lentinula edodes-Biological activity.

We hypothesized that selenium(Se)-enriched polysaccharides would possess superior biological activity when compared to those non-enriched. To verify this hypothesis, we obtained by biotechnological methods a Se-enriched analog of Japanese anticancer drug lentinan and, as a reference, the non-Se-enriched fraction..

Immune supportEnergy & fatigueMetabolic health

Maitake · 2018 · Research Article · Microbial cell factories

Improved mycelia and polysaccharide production of Grifola frondosa by controlling morphology with microparticle Talc.

BACKGROUND: Mushroom showed pellet, clump and/or filamentous mycelial morphologies during submerged fermentation. Addition of microparticles including Talc (magnesium silicate), aluminum oxide and titanium oxide could control mycelial morphologies to improve mycelia growth and secondary metabolites production..

Energy & fatigueRespiratory

Cordyceps · 2018 · Research Article · Protein & cell

Investigation on natural resources and species conservation of Ophiocordyceps sinensis, the famous medicinal fungus endemic to the Tibetan Plateau.

Metadata-grounded summary: This research article indexes research on Ophiocordyceps sinensis in Protein & cell in 2018. MycoData maps the paper to energy & fatigue, respiratory based on its title, species context, article metadata, and study classification..

Turkey Tail · 2018 · Journal Article · Environmental science and pollution research international

Removal of pharmaceutical compounds from urban wastewater by an advanced bio-oxidation process based on fungi Trametes versicolor immobilized in a continuous RBC system.

Conventional wastewater treatment plants (WWTPs) are not able to remove completely some emerging contaminants, such as residual pharmaceutical compounds (PCs) with potential ecotoxicity to water bodies..

Turkey Tail · 2017 · Research Article · Journal of biological engineering

Pretreatment of vinasse from the sugar refinery industry under non-sterile conditions by Trametes versicolor in a fluidized bed bioreactor and its effect when coupled to an UASB reactor.

BACKGROUND: During hydrous ethanol production from the sugar refinery industry in Mexico, vinasse is generated. Phenolic compounds and melanoidins contribute to its color and make degradation of the vinasse a difficult task..

Turkey Tail · 2017 · Journal Article · Applied biochemistry and biotechnology

Recovery of Phenolic Acid and Enzyme Production from Corn Silage Biologically Treated by Trametes versicolor.

Corn silage is used as high-energy forage for dairy cows and more recently for biogas production in a process of anaerobic co-digestion with cow manure. In this work, fresh corn silage after the harvest was used as a substrate in solid-state fermentations with T..

Turkey Tail · 2017 · Journal Article · Journal of chromatography. A

Refolding of laccase from Trametes versicolor using aqueous two phase systems: Effect of different additives.

Protein refolding is a strategy used to obtain active forms of proteins from inclusion bodies. On its part, laccase is an enzyme with potential for different biotechnological applications but there are few reports regarding its refolding which in many cases is considered inefficient due to the poor obtained refolding….

OncologyImmune supportCognition & nervesEnergy & fatigue

Lion's Mane · 2016 · Research Article · Immunity & ageing: I & A

Redox modulation of cellular stress response and lipoxin A4 expression by Hericium Erinaceus in rat brain: relevance to Alzheimer's disease pathogenesis.

BACKGROUND: There has been a recent upsurge of interest in complementary medicine, especially dietary supplements and foods functional in delaying the onset of age-associated neurodegenerative diseases..

OncologyImmune supportEnergy & fatigueGut & microbiome

Turkey Tail · 2022 · Research Support, Non U.S. Gov'T · The Cochrane database of systematic reviews

Coriolus (Trametes) versicolor mushroom to reduce adverse effects from chemotherapy or radiotherapy in people with colorectal cancer.

BACKGROUND: Radiotherapy and chemotherapy are used to improve survival in colorectal cancer but adverse effects can be a problem. Severe adverse effects may result in dose reduction or cessation of treatment, which have an impact on survival..

Cordyceps · 2020 · Journal Article · Journal of analytical methods in chemistry

Application of Near-Infrared Spectroscopy Analysis Technology to Total Nucleosides Quality Control in the Fermented Cordyceps Powder Production Process.

Product quality control is a prerequisite for ensuring safety, effectiveness, and stability. However, because of the different strain species and fermentation processes, there was a significant difference in quality.

Immune supportEnergy & fatigueRespiratory

Shiitake · 2020 · Journal Article · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Mixed polysaccharides derived from Shiitake mushroom, Poriacocos, Ginger, and Tangerine peel enhanced protective immune responses in mice induced by inactivated influenza vaccine.

Influenza viruses are responsible for severe respiratory tract infections of individuals and may cause pandemics with a high risk of mortality and morbidity. Although vaccination is a primary means for prevention of influenza virus infections, poor vaccine performance or inadequate immune responses limits the efficacy….

Energy & fatigueSkin & hydration

Shiitake · 2019 · Journal Article · Bioscience, biotechnology, and biochemistry

Effects of vitamin D2-fortified shiitake mushroom on bioavailability and bone structure.

Bioavailability and bone loss inhibitory effects of vitamin D2 derived from UV-irradiated shiitake mushroom were determined in vivo. The effect of the absence of ovaries on the bioavailability of vitamin D2 and bone structure was also investigated..

Shiitake · 2019 · Journal Article · Food research international (Ottawa, Ont.)

Isolation and identification of the umami peptides from shiitake mushroom by consecutive chromatography and LC-Q-TOF-MS.

Umami is critical to the taste of shiitake mushroom. To isolate and identify umami peptides, fractions from hydrolyzed dried shiitake mushroom were separated by ultrafiltration, gel filtration chromatography (GFC), and reversed-phase high-performance liquid chromatography (RP-HPLC)..

Shiitake · 2018 · Journal Article · International journal of medicinal mushrooms

Surface Decoration of Selenium Nanoparticles by Proteins from the Culinary-Medicinal Shiitake Mushroom, Lentinus edodes (Agaricomycetes), for Enhanced Fibrinolytic Activity.

Lentinus edodes (shiitake mushroom) has exhibited fibrinolytic activity. We synthesized and characterized selenium nanoparticles (SeNPs) using protein precipitated from the mushroom.

Nameko · 2016 · Journal Article · Journal of the science of food and agriculture

Purification and characterization of a ∼43 kDa antioxidant protein with antitumor activity from Pholiota nameko

BACKGROUND: Pholiota nameko water‐soluble protein (PNWSP), isolated from the dried fruiting bodies of Pholiota nameko, was purified by a successive chromatographic process using Q anion exchange column, SP cation exchange column and Superdex 200 gel filtration column..

OncologyEnergy & fatigue

Energy & fatigueRespiratory

Cordyceps · 2012 · Review · journal metadata

Cordyceps

Metadata-grounded summary: This review indexes research on Ophiocordyceps sinensis in 2012. MycoData maps the paper to energy & fatigue, respiratory based on its title, species context, article metadata, and study classification..