MycoData

OncologyImmune supportMetabolic healthLiver support

Cordyceps · 2017 · Journal Article · International journal of biological macromolecules

The preparation of three selenium-containing Cordyceps militaris polysaccharides: Characterization and anti-tumor activities.

In the present work, three fractions of selenized Cordyceps militaris polysaccharides (SeCPS) named SeCPS- I, SeCPS- II and SeCPS- III were isolated and purified by ultra-filtration. Their selenium content were measured as 541.3, 863.7 and 623.3μg/g respectively by a graphite furnace atomic absorption spectroscopy..

Immune supportSkin & hydration

Cordyceps · 2017 · Research Article · Food technology and biotechnology

The Quality Improvement of Solid-State Fermentation with Cordyceps militaris by UVB Irradiation.

Cordyceps militaris, a medicinal and edible mushroom, was used to ferment buckwheat and embryo rice by solid-state fermentation (SSF). Our aim was to investigate the effect of ultraviolet B (UVB) light irradiation on the content of vitamin D2 and biologically effective components, and antioxidant properties of….

OncologyImmune supportEnergy & fatigue

Turkey Tail · 2017 · Research Article · PloS one

Tramesan, a novel polysaccharide from Trametes versicolor. Structural characterization and biological effects.

Mushrooms represent a formidable source of bioactive compounds. Some of these may be considered as biological response modifiers; these include compounds with a specific biological function: antibiotics (e.g.

OncologyImmune supportEnergy & fatigueSkin & hydration

Snow Fungus · 2017 · Research Article · Molecular medicine reports

Tremella fuciformis polysaccharide suppresses hydrogen peroxide-triggered injury of human skin fibroblasts via upregulation of SIRT1.

Tremella fuciformis polysaccharide (TFPS), which is the extract of Tremella fuciformis Berk, has previously been demonstrated to exhibit potent anti‑oxidative, anti‑inflammatory and anti‑aging effects. However, the mechanisms underlying these protective and therapeutic effects remain to be elucidated..

Cordyceps · 2017 · Journal Article · The American journal of Chinese medicine

Uncovering the Molecular Mechanism of Anti-Allergic Activity of Silkworm Pupa-Grown Cordyceps militaris Fruit Body.

Cordyceps militaris has been widely used as an herbal drug and tonic food in East Asia and has also been recently studied in the West because of its various pharmacological activities such as antitumoral, anti-inflammatory and immunomodulatory effects..

Immune supportMetabolic healthLiver support

Niu-Chang-Chih · 2017 · Journal Article · International journal of biological macromolecules

β-d-glucan from Antrodia Camphorata ameliorates LPS-induced inflammation and ROS production in human hepatocytes.

A water soluble Antrodia Camphorata polysaccharide was composed of β-d-glucan, coded as ACP1. ACP1 was derived from cultured Antrodia Camphorata powder, which was extracted, separated and purified by DEAE-52 column and Sephadex G-100 chromatography..

Cordyceps · 2016 · Journal Article · Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials

[Metabolism Changes of Main Active Ingredients During Liquid Fermentation of Cordyceps militaris].

OBJECTIVE: To study the accumulation and changes of main active ingredients during liquid fermentation of Cordyceps militaris. METHODS: The militaris varity GIM5.

Maitake · 2016 · Journal Article · Sheng wu gong cheng xue bao = Chinese journal of biotechnology

[Structure and immunomodulatory activity of extracellular polysaccharide from Grifola frondosa].

We aimed at analyzing the structure of extracellular polysaccharide A from Grifola frondosa (EXGFP-A) and testing its immunomodulatory activity. Structural analysis shows that EXGFP-A was a contained α-D-glucoside bond and pyranose ring..

Immune supportEnergy & fatigueMetabolic health

Enoki · 2016 · Journal Article · International journal of medicinal mushrooms

Activity of Extracts from Submerged Cultured Mycelium of Winter Mushroom, Flammulina velutipes (Agaricomycetes), on the Immune System In Vitro.

Extracts from submerged cultured mycelium of two strains of Flammulina velutipes, a popular culinary mushroom, were obtained by ultrasound and tested in vitro to determine their activity in innate immunity (monocytes/ macrophages). In addition, polyclonal antibodies against the extracts were produced..

OncologyImmune supportMetabolic healthGut & microbiome

Lion's Mane · 2016 · Journal Article · International journal of medicinal mushrooms

Anti-Inflammatory Effects of Ethanol Extract of Lion's Mane Medicinal Mushroom, Hericium erinaceus (Agaricomycetes), in Mice with Ulcerative Colitis.

This study investigated the anti-inflammatory activity of ethanol extracts of Hericium erinaceus in the inflammatory bowel disease (IBD) model. Twenty C57BL/6 mice were exposed to 2% (w/v) dextran sulfate sodium (DSS) in their drinking water for 7 d to induce acute intestinal inflammation..

Cordyceps · 2016 · Research Article · Oxidative medicine and cellular longevity

Antidiabetic and Antinephritic Activities of Aqueous Extract of Cordyceps militaris Fruit Body in Diet-Streptozotocin-Induced Diabetic Sprague Dawley Rats.

Cordyceps militaris has long been used as a crude drug and folk tonic food in East Asia. The present study aims to evaluate the antidiabetic and antinephritic effects of the aqueous extract of the Cordyceps militaris fruit body (CM) in diet-streptozotocin- (STZ-) induced diabetic rats..

OncologyImmune supportEnergy & fatigue

King Oyster · 2016 · Journal Article · Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire

Antioxidant and cytotoxicites of Pleurotus eryngii residue polysaccharides obtained by ultrafiltration

Response surface methodology was used to optimize the extraction of polysaccharides Pleurotus eryngii residue (CPPS). The yield of CPPS was 10.69 ± 0.31% under the modified condition (leaching temperature of 70 °C, leaching time of 140 min and ratio of water to raw material of 25 mL/g)..

Immune supportMetabolic healthLiver support

King Oyster · 2016 · Journal Article · International journal of biological macromolecules

Antioxidant and hepatoprotective activities of intracellular polysaccharide from Pleurotus eryngii SI-04.

In present study, the intracellular polysaccharide (IPS) and its two fractions of IPS-1 and IPS-2 were obtained and purified by DEAE-52 cellulose chromatography from Pleurotus eryngii SI-04 mycelia, and their hepatoprotective effects were also investigated..

Chaga · 2016 · Journal Article · International journal of food science & technology

Ball milling improves extractability and antioxidant properties of the active constituents of mushroom Inonotus obliquus powders

Inonotus obliquus has been used as a folk remedy for a long time. An improved method using fine grinding by ball mill was investigated, and the main chemical components and physicochemical properties of Inonotus obliquus powders were analysed..

OncologyImmune supportMetabolic healthGut & microbiome

Yellow Morel · 2016 · Research Article · International journal of molecular sciences

Characteristics and Antitumor Activity of Morchella esculenta Polysaccharide Extracted by Pulsed Electric Field.

Polysaccharides from Morchella esculenta have been proven to be functional and helpful for humans. The purpose of this study was to investigate the chemical structure and anti-proliferating and antitumor activities of a Morchella esculenta polysaccharide (MEP) extracted by pulsed electric field (PEF) in submerged….

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

King Oyster · 2016 · Journal Article · Food chemistry

Characterization, antioxidative and bifidogenic effects of polysaccharides from Pleurotus eryngii after heat treatments.

Polysaccharides were extracted from freeze-dried-, oven-dried- and boiling-treated Pleurotus eryngii (FDPEPS, ODPEPS and BTPEPS). Yield of FDPEPS and its total carbohydrates, total polysaccharides, reducing sugars, phenolics and protein content were higher than ODPEPS and BTPEPS..

King Oyster · 2016 · Journal Article · International journal of biological macromolecules

Charaterization and immunomodulatory activities of polysaccharide isolated from Pleurotus eryngii.

A water-soluble polysaccharide (EPA-1) from Pleurotus eryngii was obtained using DEAE-52 and Sephadex G-50 columns. The properties, structure and immunomodulatory activity of EPA-1 were studied.

OncologyImmune supportMetabolic healthLiver support

King Oyster · 2016 · Journal Article · Carbohydrate polymers

Chemical characterization of Pleurotus eryngii polysaccharide and its tumor-inhibitory effects against human hepatoblastoma HepG-2 cells

This study was designed to investigate the chemical characterization and antitumor effects of Pleurotus eryngii polysaccharides (PEP). The crude PEP was fractionated into two fractions, namely PEP-1 and PEP-2..

Immune supportMetabolic healthSkin & hydration

Cordyceps · 2016 · Research Article · PloS one

Cordyceps militaris Treatment Preserves Renal Function in Type 2 Diabetic Nephropathy Mice.

Diabetic nephropathy is derived from long-term effects of high blood glucose on kidney function in type 2 diabetic patients. Several antidiabetic drugs and herbal medications have failed to prevent episodes of DN..

Oyster Mushroom · 2016 · Journal Article · Journal of the World Aquaculture Society

Effect of Oyster Mushroom, Pleurotus ostreatus, Extract on Hemato‐Immunological Parameters of Rainbow Trout, Oncorhynchus mykiss

The current study investigated the effects of oyster mushroom Pleurotus ostreatus, extract on immunological and hematological parameters of rainbow trout, Oncorhynchus mykiss. The fish were fed diets containing 0 (control), 1, and 2% supplementation of the oyster mushroom extract for 6 wk..

Immune supportEnergy & fatigueGut & microbiomeRespiratory

King Oyster · 2016 · Journal Article · Fish physiology and biochemistry

Effects of Eryngii mushroom (Pleurotus eryngii) and Lactobacillus plantarum on growth performance, immunity and disease resistance of Pangasius catfish (Pangasius bocourti, Sauvage 1880).

This study was conducted to evaluate the effects of Eryngii mushroom, Pleurotus eryngii (PE), and Lactobacillus plantarum single or combined on growth, innate immune response and disease resistance of the Pangasius catfish, Pangasius bocourti..

Oyster Mushroom · 2016 · Journal Article · Aquaculture

Effects of oyster mushroom (Pleurotus ostreatus) and nettle (Urtica dioica) methanolic extracts on immune responses and resistance to Aeromonas hydrophila in rainbow trout (Oncorhynchus mykiss)

In this study, immunostimulant effects of the methanolic extracts of oyster mushroom (Pleurotus ostreatus) and nettle (Urtica dioica), and disease resistance against Aeromonas hydrophila in rainbow trout (Oncorhynchus mykiss) were investigated..

Shiitake · 2016 · Research Article · PloS one

Genome Sequence of the Edible Cultivated Mushroom Lentinula edodes (Shiitake) Reveals Insights into Lignocellulose Degradation.

Lentinula edodes, one of the most popular, edible mushroom species with a high content of proteins and polysaccharides as well as unique aroma, is widely cultivated in many Asian countries, especially in China, Japan and Korea. As a white rot fungus with lignocellulose degradation ability, L..

Immune supportCognition & nerves

Lion's Mane · 2016 · Journal Article · Chinese journal of integrative medicine

Hericium erinaceus (Bull.: Fr.) Pers., a medicinal mushroom, activates peripheral nerve regeneration.

OBJECTIVE: To study the ability of aqueous extract of Hericium erinaceus mushroom in the treatment of nerve injury following peroneal nerve crush in Sprague-Dawley rats. METHODS: Aqueous extract of Hericium erinaceus was given by daily oral administration following peroneal nerve crush injury in Sprague-Dawley rats..

OncologyImmune supportMetabolic health

Maitake · 2016 · Journal Article · International journal of medicinal mushrooms

High-Level Production of Exopolysaccharides by a Cosmic Radiation-Induced Mutant M270 of the Maitake Medicinal Mushroom, Grifola frondosa (Agaricomycetes).

A new Grifola frondosa mutant, M270, was successfully isolated for high production of exopolysaccharides (EPSs) using cosmic radiation-induced mutagenesis. We found that the mutant M270 had a clearer and thicker EPS layer (~10 µm) adhering to mycelia than those of its parent strain 265 after Congo red staining..

Immune supportMetabolic healthLiver support

King Oyster · 2016 · Journal Article · International journal of biological macromolecules

Hypolipidaemic and hypoglycaemic activities of polysaccharide from Pleurotus eryngii in Kunming mice.

Therapeutic drugs must be developed to treat hyperglycaemia and hyperlipidaemia, which are major risk factors for developing coronary artery diseases and atherosclerosis. Pleurotus eryngii is a well-known food resource with functional properties in China.

Almond Mushroom · 2016 · Journal Article · Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire

Mycelial biomass and intracellular polysaccharides yield of edible mushroom Agaricus blazei produced in wheat extract medium

The aim of this work was to evaluate the potential of wheat extract as basal medium for the submerged fermentation of Agaricus blazei Murrill (ABM) and optimize the medium and fermentation conditions to obtain maximal mycelial biomass and intracellular polysaccharides (IPS) yield of this fungus..

Lion's Mane · 2016 · Journal Article · International journal of medicinal mushrooms

Nutrient Optimization Using Response Surface Methodology for Simultaneous Biomass and Bioactive Compound Production by Lion's Mane Medicinal Mushroom, Hericium erinaceus (Agaricomycetes).

Due to the unpleasant side effects of long-term use of commercially available drugs, the discovery and development of natural therapeutic agents to prevent life-debilitating diseases is urgently needed..

Immune supportMetabolic healthGut & microbiomeLiver support

Oyster Mushroom · 2016 · Journal Article · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Oral administration of an aqueous extract from the oyster mushroom Pleurotus ostreatus enhances the immunonutritional recovery of malnourished mice.

Mushroom nutriceutical components have lately attracted interest for developing immunonutritional support. However, there is relatively little information pertaining to the use of mushroom preparations for modulating the metabolic and immunological disorders associated to malnutrition..

Niu-Chang-Chih · 2016 · Research Article · Evidence-based complementary and alternative medicine: eCAM

Osteoporosis Recovery by Antrodia camphorata Alcohol Extracts through Bone Regeneration in SAMP8 Mice.

Antrodia camphorata has previously demonstrated the efficacy in treating cancer and anti-inflammation. In this study, we are the first to evaluate Antrodia camphorata alcohol extract (ACAE) for osteoporosis recovery in vitro with preosteoblast cells (MC3T3-E1) and in vivo with an osteoporosis mouse model established….

Snow Fungus · 2016 · Journal Article · Food and Bioproducts Processing

Polyethylene glycol-based ultrasound-assisted extraction and ultrafiltration separation of polysaccharides from Tremella fuciformis (snow fungus)

The polysaccharides of Tremella fuciformis were extracted using an aqueous solution of polyethylene glycol and then separated by ultrafiltration. To obtain the optimal extraction conditions, the effects of different experimental factors on the extraction yield of polysaccharides of T.

Zhu Ling · 2016 · Journal Article · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Polyporus umbellatus inhibited tumor cell proliferation and promoted tumor cell apoptosis by down-regulating AKT in breast cancer.

Breast cancer (BC) is the foremost cause of cancer-related mortality in women worldwide. Polyporus umbellatus is a polysaccharide preparation of the Chinese traditional herb medicine, which has been explored as an inhibitory compounds in suppressing many cancers..

Cordyceps · 2016 · Journal Article · International journal of biological macromolecules

Preparation and inhibition on α-d-glucosidase of low molecular weight polysaccharide from Cordyceps militaris.

The structural properties and the inhibition on α-d-glucosidase activity of the low molecular weight (LCMPs-II) obtained from the optimized acid hydrolysis of the Cordyceps militaris polysaccharides (CMPs) were investigated in this paper..

Snow Fungus · 2016 · Journal Article · Food & function

Protective effect of Tremella fuciformis Berk extract on LPS-induced acute inflammation via inhibition of the NF-κB and MAPK pathways.

Tremella fuciformis Berk (TFB) has long been used as a traditional medicine in Asia. Although TFB exhibits antioxidant and anti-inflammatory effects, the mechanisms of action responsible have remained unknown..

OncologyImmune supportMetabolic health

Chaga · 2016 · Research Article · International journal of molecular sciences

Renal Protective Effects of Low Molecular Weight of Inonotus obliquus Polysaccharide (LIOP) on HFD/STZ-Induced Nephropathy in Mice.

Diabetic nephropathy (DN) is the leading cause of end-stage renal disease in diabetes mellitus. Oxidative stress, insulin resistance and pro-inflammatory cytokines have been shown to play an important role in pathogeneses of renal damage on type 2 diabetes mellitus (DM)..

King Oyster · 2016 · Journal Article · Steroids

Six new ergostane-type steroids from king trumpet mushroom (Pleurotus eryngii) and their inhibitory effects on nitric oxide production.

Six new ergostane-type steroids; (22E)-3β,5α,6α,11-tetrahydroxy-9(11)-seco-ergosta-7,22-dien-9-one (1), (22E)-8,14-epoxyergosta-6,22-diene-3β,5α,9α-triol (2), (22E)-4α,5α-epoxyergosta-7,22-diene-3β,6β-diol (3), (22E)-3β,4β,5α-trihydroxyergosta-7,22-dien-6-one (4), (22E)-ergosta-7,22-diene-3β,5β,6α-triol (5), and….

Immune supportEnergy & fatigueSkin & hydration

Enoki · 2016 · Journal Article · International journal of medicinal mushrooms

Structural Characterization and Immunological Activities of a Novel Water-Soluble Polysaccharide from the Fruiting Bodies of Culinary-Medicinal Winter Mushroom, Flammulina velutipes (Agaricomycetes).

A water-soluble polysaccharide, designated FVPA2, was isolated from the fruiting bodies of Flammulina velutipes using DEAE Sepharose Fast Flow and gel-permeation chromatography..

Immune supportEnergy & fatigue

Zhu Ling · 2016 · Journal Article · Carbohydrate polymers

Structure and bioactivity of a polysaccharide containing uronic acid from Polyporus umbellatus sclerotia

Polyporus umbellatus is a medicinal fungus, has been used in traditional Chinese medicine for thousands years for treatment of edema, scanty urine, vaginal discharge, jaundice and diarrhea..

Immune supportEnergy & fatigue

Zhu Ling · 2016 · Journal Article · Carbohydrate polymers

Structure and bioactivity of a polysaccharide containing uronic acid from Polyporus umbellatus sclerotia.

Polyporus umbellatus is a medicinal fungus, has been used in traditional Chinese medicine for thousands years for treatment of edema, scanty urine, vaginal discharge, jaundice and diarrhea..

OncologyImmune supportCognition & nervesEnergy & fatigue

Snow Fungus · 2016 · Journal Article · Molecular medicine reports

Studies on the purification of polysaccharides separated from Tremella fuciformis and their neuroprotective effect.

The present study aimed to investigate the protective effect of purified polysaccharides from Tremella fuciformis against glutamate-induced cytotoxicity in differentiated PC12 (DPC12) cells..

Cordyceps · 2016 · Journal Article · International journal of biological macromolecules

Synthesis, characterization and antioxidant activity of selenium polysaccharide from Cordyceps militaris.

A purified selenium-containing derivatives of Cordyceps militaris polysaccharide synthesized using H2SeO3/HNO3 and BaCl2 as a catalyst was investigated in this paper. The reaction condition was optimized by selecting different reaction temperature and period..

OncologyImmune supportGut & microbiome

Almond Mushroom · 2016 · Research Article · PloS one

The Agaricus blazei-Based Mushroom Extract, Andosan™, Protects against Intestinal Tumorigenesis in the A/J Min/+ Mouse.

BACKGROUND: The novel A/J Min/+ mouse, which is a model for human Familial Adenomatous Polyposis (FAP), develops spontaneously multiple adenocarcinomas in the colon as well as in the small intestine..

King Oyster · 2016 · Journal Article · Journal of microbiology and biotechnology

The Anti-Adipogenic Activity of a New Cultivar, Pleurotus eryngii var. ferulae 'Beesan No. 2', through Down-Regulation of PPAR γ and C/EBP α in 3T3-L1 Cells.

Adipogenesis is one of the cellular processes and a highly controlled program. Nowadays, inhibition of adipogenesis has received attention as an effective way to regulate obesity.

Immune supportCognition & nervesEnergy & fatigueMetabolic health

Lion's Mane · 2015 · Review · Journal of agricultural and food chemistry

Chemistry, Nutrition, and Health-Promoting Properties of Hericium erinaceus (Lion's Mane) Mushroom Fruiting Bodies and Mycelia and Their Bioactive Compounds.

The culinary and medicinal mushroom Hericium erinaceus is widely consumed in Asian countries, but apparently not in the United States, for its nutritional and health benefits..

OncologyImmune supportCognition & nervesMetabolic health

Lion's Mane · 2014 · Review · Food & function

Hericium erinaceus (Yamabushitake): a unique resource for developing functional foods and medicines.

Hericium erinaceus (HE) is a fungus inhabiting the mountainous areas of the northeast territories in Asia. HE has been used in traditional folk medicine and medicinal cuisine in China, Korea and Japan..

OncologyImmune supportCognition & nervesEnergy & fatigue

Cordyceps · 2013 · Review Article · Journal of traditional and complementary medicine

A Systematic Review of the Mysterious Caterpillar Fungus Ophiocordyceps sinensis in Dong-ChongXiaCao ( Dōng Chóng Xià Cǎo) and Related Bioactive Ingredients.

The caterpillar fungus Ophiocordyceps sinensis (syn.Cordyceps sinensis), which was originally used in traditional Tibetan and Chinese medicine, is called either "yartsa gunbu" or "DongChongXiaCao ( Dōng Chóng Xià Cǎo)" ("winter worm-summer grass"), respectively..

OncologyImmune supportCognition & nervesMetabolic health

Lion's Mane · 2013 · Review · Journal of complementary & integrative medicine

Hericium erinaceus: an edible mushroom with medicinal values.

Mushrooms are considered as nutritionally functional foods and source of physiologically beneficial medicines. Hericium erinaceus, also known as Lion's Mane Mushroom or Hedgehog Mushroom, is an edible fungus, which has a long history of usage in traditional Chinese medicine..

Cordyceps · 2013 · Review · International journal of medicinal mushrooms

The artificial cultivation of medicinal Caterpillar Fungus, Ophiocordyceps sinensis (Ascomycetes): a review.

Caterpillar fungus, Ophiocordyceps sinensis (syn. Cordyceps sinensis), is highly valued in China as a dietary supplement or tonic food and natural remedy.