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Immune supportEnergy & fatigueMetabolic health

Chaga · 2025 · Journal Article · Journal of Chromatography A

Supercritical fluid-based protocol for the identification and quantitation of triterpenoids in commercial Inonotus obliquus (chaga) samples

Inonotus obliquus is a fungal pathogen that parasitizes the trunks of broadleaved tree species. The sclerotia of this fungus, so-called chaga, show a broad range of traditional and medicinal uses..

Immune supportEnergy & fatigueMetabolic health

Chaga · 2025 · Journal Article · Journal of chromatography. A

Supercritical fluid-based protocol for the identification and quantitation of triterpenoids in commercial Inonotus obliquus (chaga) samples.

Inonotus obliquus is a fungal pathogen that parasitizes the trunks of broadleaved tree species. The sclerotia of this fungus, so-called chaga, show a broad range of traditional and medicinal uses..

Reishi · 2025 · Journal Article · International journal of biological macromolecules

Synergistic anti-inflammatory effects of Ganoderma lucidum polysaccharide and ganoderic acid A on LPS-induced RAW264.7 cells by inhibition of TLR4/NF-κB activation.

Ganoderma lucidum, a food-grade medicinal mushroom, is rich in biologically active components that offer significant health benefits. This study investigated the synergistic anti-inflammatory effects of Ganoderma lucidum polysaccharide (GLP-1) and ganoderic acid A (GAA) in RAW264.7 cells..

OncologyImmune supportEnergy & fatigue

Cordyceps · 2025 · Research Article · Journal of fungi (Basel, Switzerland)

Telomere-to-Telomere Assembly of the Cordyceps militaris CH1 Genome and Integrated Transcriptomic and Metabolomic Analyses Provide New Insights into Cordycepin Biosynthesis Under Light Stress.

Cordyceps militaris, a model species in the genus Cordyceps, is widely distributed globally and is known for its significant medicinal value. It has been traditionally used in Chinese medicine to enhance immunity, alleviate fatigue, and treat tumors, among other therapeutic purposes..

OncologyImmune supportEnergy & fatigueRespiratory

Cordyceps · 2025 · Research Article · Journal of microbiology and biotechnology

The Inhibitory Effects of Cordyceps militaris ARA301 Extract on Lipopolysaccharide-Induced Lung Injury in vivo.

Lung injury is a critical health concern associated with severe inflammatory responses and tissue damage that can weaken respiratory function and potentially become life-threatening in severe cases..

Oyster Mushroom · 2025 · Research Article · Journal of fungi (Basel, Switzerland)

The Mechanism of Ammonia-Assimilating Bacteria Promoting the Growth of Oyster Mushrooms (Pleurotus ostreatus).

Oyster mushrooms (Pleurotus ostreatus) are one of the most commonly grown edible mushrooms using compost, which contains high concentrations of ammonia. In this study, inoculation of the oyster mushroom culture substrate with ammonia-assimilating bacterium Enterobacter sp..

Energy & fatigueMetabolic healthGut & microbiome

King Oyster · 2025 · Research Article · Foods (Basel, Switzerland)

The Performance of Pleurotus eryngii β-Glucans on Protein Digestion and the Release of Free Amino Acids in the Bloodstream of Obese Adults.

Pleurotus eryngii is an edible mushroom with previously characterized β-glucans. Its potential to ameliorate postprandial glycemia and regulate appetite at the postprandial state has been previously shown.

OncologyEnergy & fatigueLiver supportRespiratory

Reishi · 2025 · Research Article · AMB Express

Unlocking Reishi's secrets: nutritional and medicinal traits of Ganoderma lucidum isolated from tree bark in Egypt.

Ganoderma lucidum is an edible mushroom with high consumption rates in many cultures especially East Asian. This study assessed the in-vitro antimicrobial, antitumor, antiviral as well as antioxidant capacity of Ganoderma lucidum water extract (GLWE)..

Reishi · 2025 · Journal Article · Journal of the Air & Waste Management Association (1995)

Valorization of date palm waste as a substrate for Reishi medicinal mushroom (Ganoderma lucidum) cultivation.

Ganoderma lucidum, commonly known as Reishi mushroom, is highly valued for its medicinal properties and economic importance. Date palm residues (DPR) offer a sustainable and cost-effective substrate for mushroom cultivation by promoting the efficient utilization of agricultural waste efficiently..

Energy & fatigueMetabolic healthGut & microbiomeSkin & hydration

Maitake · 2024 · Journal Article · International journal of biological macromolecules

A novel angiotensin I-converting enzyme inhibitory peptide APPLRP from Grifola frondosa ameliorated the Ang II-induced vascular modeling in zebrafish model by mediating smooth muscle cells.

Grifola frondosa has garnered significant popularity as an edible mushroom attributable to its exceptional taste and nutritional benefits. This study isolated APPLRP, a potent ACE-inhibitory peptide, from the alcohol-soluble fraction of Grifola frondosa..

King Oyster · 2024 · Preprint · journal metadata

A Pleurotus eryngii based biomass porous carbon encapsulated phase change material for efficient thermal energy storage

With the sharp increase in modern energy consumption, phase change composites with the characteristics of rapid preparation are employed for thermal energy storage to meet the challenge of energy crisis..

Cordyceps · 2024 · Journal Article · International journal of biological macromolecules

An sn-2 regioselective lipase with cis-fatty acid preference from Cordyceps militaris: Biochemical characterization and insights into its regioselective mechanism.

Lipase with unique regioselectivity is an attractive biocatalyst for elaborate lipid modification. However, the excavation of novel sn-2 regioselective lipases is difficult due to their scarcity in nature, with Candida antarctica lipase A (CALA) being the pronouncedly reported one..

Cordyceps · 2024 · Research Article · Scientific reports

Analysis of metabolic spectrum characteristics of naturally and cultivated Ophiocordyceps sinensis based on non-targeted metabolomics.

The analysis of the differences in metabolic profiles between naturally Ophiocordyceps sinensis (NO) and cultivated Ophiocordyceps sinensis (CO) is an essential process for the medicinal value mining of Ophiocordyceps sinensis..

OncologyImmune supportEnergy & fatigueSkin & hydration

Almond Mushroom · 2024 · Research Article · International journal of molecular sciences

Anti-Photodamage Effect of Agaricus blazei Murill Polysaccharide on UVB-Damaged HaCaT Cells.

UVB radiation is known to induce photodamage to the skin, disrupt the skin barrier, elicit cutaneous inflammation, and accelerate the aging process. Agaricus blazei Murill (ABM) is an edible medicinal and nutritional fungus..

Oyster Mushroom · 2024 · Research Article · Frontiers in nutrition

Antioxidant capacities and non-volatile metabolites changes after solid-state fermentation of soybean using oyster mushroom (Pleurotus ostreatus) mycelium.

Given the abundance of beneficial properties and enzymes secreted by edible oyster mushrooms, their mycelium could serve as a starter for fermented foods to enhance their nutritional and bioactive quality..

Reishi · 2024 · Research Article · Frontiers in nutrition

Application of Electronic tongue and HPLC in rapid determination of functional triterpenes and origins of Ganoderma lucidum.

INTRODUCTION: Ganoderma lucidum is one well known functional food resource. The triterpenes, such as Ganoderic acid A and Ganoderic acid D, as well as the sensory characteristics could reflect the quality of G.

Energy & fatigueMetabolic healthSkin & hydration

Cordyceps · 2024 · Research Article · BMC genomics

Combined metabolome and transcriptome analysis reveal the mechanism of water stress in Ophiocordyceps sinensis.

BACKGROUND: Ophiocordyceps sinensis (O. sinensis) is the dominant bacterium in the asexual stage of Chinese cordyceps, and its growth usually suffers from water stress.

Cognition & nervesEnergy & fatigue

Lion's Mane · 2024 · Research Article · ACS omega

Combining Deep Learning and Structural Modeling to Identify Potential Acetylcholinesterase Inhibitors from Hericium erinaceus.

Alzheimer's disease (AD) is the most common type of dementia, affecting over 50 million people worldwide. Currently, most approved medications for AD inhibit the activity of acetylcholinesterase (AChE), but these treatments often come with harmful side effects..

Oyster Mushroom · 2024 · Research Article · Scientific reports

Comparative antioxidant activity and phytochemical content of five extracts of Pleurotus ostreatus (oyster mushroom).

Reactive oxygen species reacts with numerous molecules in the body system causing oxidative damage, which requires antioxidants to ameliorate. Pleurotus ostreatus, a highly nutritious edible mushroom, has been reported to be rich in bioactive compounds..

Enoki · 2024 · Journal Article · Journal of food composition and analysis

Comparative Assessment of β-glucan Composition and Structural Characterization in Wild and Commercial Enoki Mushrooms, Flammulina velutipes

This study investigated the β-glucan content and structure in an indigenous Enoki mushroom compared with a European commercial strain. Both Enoki types belonged to the same species, Flammulina velutipes, and grew on the same substrate..

Oyster Mushroom · 2024 · Research Article · Frontiers in microbiology

Contrasting effects of NADPH oxidases on the fungal hyphae growth and immune responses in Pleurotus ostreatus.

Pleurotus ostreatus is one of the most consumed mushroom species, as it serves as a high-quality food, favors a rich secondary metabolism, and has remarkable adaptability to the environment and predators..

Immune supportEnergy & fatigueGut & microbiome

Cordyceps · 2024 · Research Article · Journal of animal science

Effect of cordyceps militaris on growth performance, antioxidant capacity, and intestinal epithelium functions in weaned pigs.

To explore the effects of cordyceps militaris (CM) on growth performance and intestinal epithelium functions, 180 weaned pigs were randomly assigned into 5 treatments with 6 replicate pens per treatment (6 pigs per pen)..

OncologyImmune supportEnergy & fatigueMetabolic health

Enoki · 2024 · Research Article · Scientific reports

Effect of Flammulina velutipes polysaccharide on mitochondrial apoptosis in lung adenocarcinoma A549 cells.

FVP is a polysaccharide extracted from Flammulina velutipes with immunomodulatory, anti-tumor, and anti-oxidation activities. In this study, we obtained the crude polysaccharide FVP-C from the water extract of Flammulina velutipes, and its main component FVP-S1 was obtained after further purification..

Cordyceps · 2024 · Randomized Controlled Trial · Nutrients

Effect of the Administration of Cordyceps militaris Mycelium Extract on Blood Markers for Anemia in Long-Distance Runners.

In the present study, we conducted a placebo-controlled, double-blind, parallel-group comparison trial in which an extract of Cordyceps militaris (CM) mycelium was administered to long-distance runners for 16 weeks during the pre-season training period and blood test markers for anemia were investigated..

Immune supportEnergy & fatigueMetabolic health

Wood Ear · 2024 · Journal Article · Phytomedicine: international journal of phytotherapy and phytopharmacology

Effects of Auricularia auricula-judae (Bull.) Quél. polysaccharide acid hydrolysate on glucose metabolism in diabetic mice under oxidative stress.

BACKGROUND: Oxidative stress can lead to uncontrolled glucose metabolism and, thus, diabetes. Auricularia auricula-judae (Bull.) Quél.

OncologyEnergy & fatigueMetabolic healthSkin & hydration

Shiitake · 2024 · Research Article · Foods (Basel, Switzerland)

Effects of Balsa Fish Skin Gelatin, Lentinula edodes Mushrooms, Soy Protein Isolate, and Starch on the Sensory Quality and Characterization of Physicochemical and Antioxidant Properties of New Sausage.

Sausages are loved by people for their unique texture, satisfying chewiness, and pleasant flavor. However, in the production of sausages, red meat and a large amount of fat are mainly used, and long-term consumption will increase the risk of diseases such as obesity, heart disease, hypertension, and cancer..

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

Reishi · 2024 · Journal Article · Aquaculture

Effects of dietary reishi mushroom (Ganoderma lucidum) on the growth performance of Nile tilapia, Oreochromis niloticus juveniles

In aquaculture, several medicinal mushrooms have been successfully used as prebiotics, with attractive growth-stimulant, immune-modulatory, and antioxidant functions for several finfish species..

Cognition & nervesEnergy & fatigue

Cordyceps · 2024 · Research Article · Metabolites

Effects of Different Drying Methods on Amino Acid Metabolite Content and Quality of Ophiocordyceps sinensis by LC-MS/MS Combined with Multivariate Statistical Methods.

Ophiocordyceps sinensis, a medicinal fungus utilized in traditional Chinese medicine, exhibits a range of biological activities and pharmacological functions. In this study, we determined the amino acid composition of 94 amino acids in Ophiocordyceps sinensis using liquid chromatography-tandem mass spectrometry….

King Oyster · 2024 · Journal Article · Journal of food engineering

Effects of gums on 3D printing performance of Pleurotus eryngii powder

Pleurotus eryngii has rich nutritional activity, but its application in 3D printing was limited due to the high content of dietary fiber. To solve this problem, we added six gums (gellan gum, pectin, guar gum, locust bean gum, sodium alginate, methylcellulose) to improve the 3D printing performance of Pleurotus….

Immune supportEnergy & fatigueGut & microbiome

Reishi · 2024 · Randomized Controlled Trial, Veterinary · Animal biotechnology

Effects of JUNCAO Ganoderma lucidum polysaccharide peptide on slaughter performance and intestinal health of Minxinan black rabbits.

This experiment was conducted to investigate the effects of JUNCAO Ganoderma lucidum polysaccharide peptide (JCGLPP) on slaughter performance and intestinal health of Minxinan black rabbits, which aimed to provide the basis for the application of JCGLPP in meat rabbits..

Energy & fatigueGut & microbiome

Oyster Mushroom · 2024 · Research Article · Poultry science

Effects of oyster mushroom (Pleurotus ostreatus) stem residue supplementation on growth performance, meat quality and health status of broilers.

Oyster mushroom stem residue, a by-product with medicinal and nutritive values, might be a prospective feed supplement in poultry nutrition. The study focused on evaluating the impact of oyster mushroom (Pleurotus ostreatus) stem residue (OMSR) powder supplementation on growth performance, carcass traits, meat….

Cognition & nervesEnergy & fatigue

Reishi · 2024 · Randomized Controlled Trial · International journal of medicinal mushrooms

Efficacy of Lingzhi or Reishi Medicinal Mushroom Ganoderma lucidum (Agaricomycetes) Supplementation on Psychological Stress and Selective Fitness Profile Parameters in Female College Students in West Bengal, India.

Psychological disparities impact physical activity and fitness in sedentary female college students by affecting cardiovascular efficiency. Ganoderma lucidum, vitality-enhancing herb alleviates health and rejuvenates the mind-body to improve endurance fitness..

Oyster Mushroom · 2024 · Journal Article · International journal of medicinal mushrooms

Enhancing Biomass and β-Glucan Yield from Oyster Mushroom Pleurotus ostreatus (Agaricomycetes) Mycelia through Extract Valorization.

This study aimed to examine the impact of mushroom extract-based solid media on the β-glucan content, growth rate, density, and biomass content of Pleurotus ostreatus (oyster mushroom) mycelia. Fresh, high-quality raw P..

Immune supportEnergy & fatigueMetabolic healthRespiratory

Cordyceps · 2024 · Journal Article · Journal of biomolecular structure & dynamics

Evaluation of Cordyceps militaris steroids as anti-inflammatory agents to combat the Covid-19 cytokine storm: a bioinformatics and structure-based drug designing approach.

Since the SARS-CoV-2 epidemic, researchers have been working on figuring out ways to tackle multi-organ failure and hyperinflation, which are brought on by a cytokine storm..

Oyster Mushroom · 2024 · Research Article · International journal of medical sciences

Evaluation of oyster mushroom (Pleurotus ostreatus)-derived anthraquinone on the induction of apoptosis and suppression of MMP-2 and MMP-9 expression in breast cancer cells.

Introduction: Breast cancer results from tissue degradation caused by environmental and genetic factors that affect cells in the body. Matrix metalloproteinases, such as MMP-2 and MMP-9, are considered potential putative markers for tumor diagnosis in clinical validation due to their easy detection in body fluids..

OncologyEnergy & fatigue

Immune supportEnergy & fatigueGut & microbiome

King Oyster · 2024 · Research Article · Nutrients

Evaluation of Physicochemical Properties and Prebiotics Function of a Bioactive Pleurotus eryngii Aqueous Extract Powder Obtained by Spray Drying.

A bioactive Pleurotus eryngii aqueous extract powder (SPAE) was obtained by spray drying and its performance in terms of physicochemical properties, in vitro digestion, inflammatory factors, and modulation of the intestinal microbiota was explored..

Cordyceps · 2024 · Journal Article · International journal of medicinal mushrooms

Evidence for Regulation of Cordycepin Biosynthesis by Transcription Factors Krüppel-Like Factor 4 and Retinoid X Receptor Alpha in Caterpillar Medicinal Mushroom Cordyceps militaris (Ascomycetes).

Cordyceps militaris, Chinese traditional medicinal fungus, has many bioactive properties. Cordycepin (3'-deoxyadenosine) is a major bioactive component of C.

OncologyImmune supportEnergy & fatigue

Reishi · 2024 · Review · Journal of clinical medicine

Exploring the Therapeutic Potential of Ganoderma lucidum in Cancer.

Triterpenoids, such as ganoderic acid, and polysaccharides, including β-D-glucans, α-D-glucans, and α-D-mannans, are the main secondary metabolites of the medicinal fungus Ganoderma lucidum..

Energy & fatigueSkin & hydration

Shiitake · 2024 · Journal Article · Journal of wood science

Fuel and material utilization of a waste shiitake (Lentinula edodes) mushroom bed derived from hardwood chips I: characteristics of calorific value in terms of elemental composition and ash content

To understand the fuel characteristics of a waste shiitake mushroom bed derived from hardwood chips, the moisture content at the time of disposal and after 1 month, as well as its calorific value, ash content, and elemental composition, were investigated..

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

Reishi · 2024 · Journal Article · International journal of biological macromolecules

Ganoderma lucidum polysaccharide promotes broiler health by regulating lipid metabolism, antioxidants, and intestinal microflora.

Ganoderma lucidum polysaccharides (GLP) are the primary bioactive macromolecular compounds of Ganoderma lucidum, possessing antioxidant and immunomodulatory effects. Hot water extract of Juncao-substrate Ganoderma Lucidum residue (HWE-JGLR) is abundant in GLP..

Cordyceps · 2024 · Research Article · Genes

Genomic and Transcriptome Analysis Reveals the Biosynthesis Network of Cordycepin in Cordyceps militaris.

Cordycepin is the primary active compound of Cordyceps militaris. However, the definitive genetic mechanism governing cordycepin synthesis in fruiting body growth and development remains elusive, necessitating further investigation.

Cordyceps · 2024 · Journal Article · Gene

Holistic transcriptional responses of Cordyceps militaris to different culture temperatures.

Cordyceps militaris is a medicinal entomopathogenic fungus containing valuable biometabolites for pharmaceutical applications. Its genetic inheritance and environmental factors play a crucial role in the production of biomass enriched with cordycepin..

Energy & fatigueGut & microbiomeSkin & hydration

King Oyster · 2024 · Research Article · Foods (Basel, Switzerland)

Identification of Peptides from Edible Pleurotus eryngii Mushroom Feet and the Effect of Delaying D-Galactose-Induced Senescence of PC12 Cells Through TLR4/NF-κB/MAPK Signaling Pathways.

Pleurotus eryngii mushroom has been proven to have anti-aging bioactivities. However, few studies have focused on edible Pleurotus eryngii mushroom feet peptides (PEMFPeps)..

King Oyster · 2024 · Research Article · Molecules (Basel, Switzerland)

Increased Antioxidant Performance of Lignin by Biodegradation Obtained from an Extract of the Mushroom Pleurotus eryngii.

The aim of this study was to evaluate the antioxidant properties of the products derived from the biodegradation of lignin by the ligninolytic enzymes present in an aqueous extract of the mushroom P. eryngii.

Cordyceps · 2024 · Journal Article · International journal of biological macromolecules

Inhibition mechanism of cordycepin and ergosterol from Cordyceps militaris Link. against xanthine oxidase and cyclooxygenase-2.

Cordyceps militaris Link. (C.

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

Chaga · 2024 · Journal Article · Toxicology mechanisms and methods

Inonotus obliquus aqueous extract inhibits intestinal inflammation and insulin metabolism defects in Drosophila.

In biomedical research, the fruit fly (Drosophila melanogaster) is among the most effective and flexible model organisms. Through the use of the Drosophila model, molecular mechanisms of human diseases can be investigated and candidate pharmaceuticals can be screened..

Cognition & nervesEnergy & fatigueSkin & hydration

Reishi · 2024 · Journal Article · Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire

Integrating convolutional neural networks with UV–Vis spectroscopy for monitoring the extraction procedure of Ganoderma lucidum spore powder

The rise of Ganoderma lucidum spores as a nutraceutical is gaining sharp acceptance and popularity. Aqueous extraction is the primary means of obtaining phytochemicals from the spores..

Almond Mushroom · 2024 · Research Article · Scientific reports

Kiwifruit-Agaricus blazei intercropping effectively improved yield productivity, nutrient uptake, and rhizospheric bacterial community.

Intercropping systems have garnered attention as a sustainable agricultural approach for efficient land use, increased ecological diversity in farmland, and enhanced crop yields..

Shiitake · 2024 · Research Article · Frontiers in microbiology

Lentinula edodes substrate formulation using multilayer perceptron-genetic algorithm: a critical production checkpoint.

Shiitake (Lentinula edodes) is one of the most widely grown and consumed mushroom species worldwide. They are a potential source of food and medicine because they are rich in nutrients and contain various minerals, vitamins, essential macro- and micronutrients, and bioactive compounds..