MycoData

Turkey Tail · 2024 · Research Article · Indian journal of microbiology

Production, Purification and Immobilization of Laccase from Trametes versicolor HBB 7328 for its Role in Decolorization of Textile Dyes.

Laccase is an extracellular enzyme that is widely used in the decolonization of textile dyes in waste water. The aim of our study was to isolate, purify, characterize and immobilize the laccase enzyme produced by Trametes versicolor HBB 7328..

Reishi · 2024 · Review · Heliyon

Research progress of Ganoderma lucidum polysaccharide in prevention and treatment of Atherosclerosis.

Atherosclerosis (AS) is a chronic inflammatory disease resulting from dysregulated lipid metabolism, constituting the pathophysiological foundation of cardiovascular and cerebrovascular diseases. AS has a high incidence rate and mortality rate worldwide..

Lion's Mane · 2024 · Preprint · journal metadata

Role of Hericium Erinaceus as a Probiotic Stimulant

Abstract Lion's Mane mushroom ( Hericium erinaceus ) is gaining scientific interest for its potential health benefits, particularly its bioactive compounds and probiotic-stimulatory properties..

Shiitake · 2024 · Journal Article · Journal of food composition and analysis

Selenium speciation analysis of selenium-enriched Shiitake mushrooms (Lentinula edodes) by HPLC-ESI-MS

Selenium (Se) is an essential component of critical enzymes and is intricately linked to human health. Shiitake mushrooms (Lentinula edodes) are considered as good dietary supplements for producing Se-enriched foods due to their high protein content and ability to absorb minerals from growth substrates..

OncologyImmune supportMetabolic healthGut & microbiome

Shiitake · 2024 · Journal Article · Carbohydrate polymers

Simulated human digestion and fermentation of a high-molecular weight polysaccharide from Lentinula edodes mushroom and protective effects on intestinal barrier

Lentinula edodes (Shiitake) is an important edible mushroom and polysaccharides are its major constituents with proven health benefits. The study was to investigate the gut bacterial fermentation and subsequent effects on gut barrier function of a glucan-rich polysaccharide, LePS40 precipitated from the mushroom water….

OncologyImmune supportEnergy & fatigueGut & microbiome

Cordyceps · 2024 · Preprint · journal metadata

Solid-state fermentation product of Cordyceps militaris enhances the antioxidation and modulates immune response in grower pigs

Abstract Background: Pathogenic infections can significantly impact the health of livestock. Traditionally, antibiotic growth promoters (AGPs) have been used in feed to enhance growth performance and disease control..

Maitake · 2024 · Journal Article · Carbohydrate research

Structural characterization and immunomodulatory effect of a starch-like Grifola frondosa polysaccharides on cyclophosphamide-induced immunosuppression in mice.

In this study, a pure Grifola frondosa polysaccharide (GFP-1) was extracted and purified from Grifola frondosa. By HPLC, GC-MS, FT-IR, and NMR analysis, GFP-1 was determined to be a starch-like polysaccharide with an average molecular weight of 3370 kDa..

OncologyImmune supportGut & microbiomeLiver support

Reishi · 2024 · Research Article · Molecules (Basel, Switzerland)

Structure Identification of Ganoderma lucidum Spore Polysaccharides and Their Antitumor Activity In Vivo.

Ganoderma lucidum spore powder, valued for its nutritional and medicinal properties, contains polysaccharides crucial for its efficacy. However, the complex structural nature of these polysaccharides necessitates further investigation to fully realize their potential..

OncologyImmune supportEnergy & fatigueGut & microbiome

Cordyceps · 2024 · Research Article · BMC veterinary research

Synergistic fermentation of Cordyceps militaris and herbal substrates boosts grower pig antioxidant and immune function.

BACKGROUND: Pathogenic infections can significantly impact the health of livestock. Traditionally, antibiotic growth promoters (AGPs) have been used in feed to enhance growth performance and disease control..

OncologyImmune supportEnergy & fatigueGut & microbiome

Reishi · 2024 · Clinical Trial Protocol · BMC complementary medicine and therapies

Synergy of de-walled Ganoderma Lucidum spore powder (GLSP) on targeted therapy in advanced non-squamous non-small cell lung cancer with epidermal growth factor receptor (EGFR) mutant: protocol for a randomized, double-blind, placebo-controlled study.

BACKGROUND: Osimertinib is regarded as a promising third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) for advanced non-squamous non-small cell lung cancer (NSCLC) patients who developed T790M..

Immune supportEnergy & fatigueGut & microbiome

King Oyster · 2024 · Research Article · Food science & nutrition

The effect of in vitro digestion on the interaction between polysaccharides derived from Pleurotus eryngii and intestinal mucus.

Pleurotus eryngii polysaccharides (PEPs) have been proven to display multiple activities through digestive system action, from which the digestion products should first interact with intestinal mucus (MUC), followed by the function of intestinal cells..

Lion's Mane · 2024 · Review · Journal of physiology and pharmacology: an official journal of the Polish Physiological Society

The potential therapeutic role of Hericium erinaceus extract in pathologic conditions involving the urogenital-gut axis: insights into the involved mechanisms and mediators.

In this review we focused on the putative therapeutic effect of Hericium erinaceus extract in the treatment of pathologic conditions of the lower urinary tract in which intestinal inflammation may play a role..

Metabolic healthGut & microbiome

Reishi · 2024 · Journal Article · Animal science journal = Nihon chikusan Gakkaiho

Time-dependent change in Reishi (Ganoderma lingzhi) triterpenoids in culture with rumen fluid.

The purpose of this study was to investigate the time-dependent change in Reishi (Ganoderma lingzhi) triterpenoids in rumen fluid. G.

Metabolic healthGut & microbiome

Reishi · 2024 · Journal Article · Animal science journal =

Time‐dependent change in Reishi (Ganoderma lingzhi) triterpenoids in culture with rumen fluid

The purpose of this study was to investigate the time‐dependent change in Reishi (Ganoderma lingzhi) triterpenoids in rumen fluid. G.

King Oyster · 2024 · Research Article · Life (Basel, Switzerland)

Valorization of Ginkgo biloba Leaf Powder as a Substrate in King Oyster Mushroom (Pleurotus eryngii) Cultivation.

Ginkgo biloba is widely planted as a colorful foliage tree, and its leaf can be used as a biomass energy source, but it has been underutilized for a long time. The aim of this study was to investigate the potential of garden waste as a substrate component in the cultivation process of the king oyster mushroom….

OncologyEnergy & fatigueGut & microbiome

Cordyceps · 2024 · Research Article · Molecules (Basel, Switzerland)

Verification of In Vitro Anticancer Activity and Bioactive Compounds in Cordyceps Militaris-Infused Sweet Potato Shochu Spirits.

Many liqueurs, including spirits infused with botanicals, are crafted not only for their taste and flavor but also for potential medicinal benefits. However, the scientific evidence supporting their medicinal effects remains limited..

Shiitake · 2023 · Randomized Controlled Trial · Nutrition and cancer

Efficacy of Lentinula edodes Mycelia Extract on Chemotherapy-Related Tasted Disorders in Pancreatic Cancer Patients.

Patients undergoing chemotherapy suffer from taste disorders that affect the quality of life (QOL). In this study, a randomized, double-blind, placebo-controlled trial was conducted to explore the effectiveness of AHCC®, a standardized extract of cultured Lentinula edodes mycelia, for chemotherapy-related adverse….

OncologyGut & microbiome

Cordyceps · 2022 · Review · Microorganisms

Cordyceps militaris as a Bio Functional Food Source: Pharmacological Potential, Anti-Inflammatory Actions and Related Molecular Mechanisms.

Cordyceps militaris (C. militaris) is a medicinal mushroom possessing a variety of biofunctionalities.

Oyster Mushroom · 2021 · Randomized Controlled Trial, Veterinary · Journal of dairy science

Enzymatic effects of Pleurotus ostreatus spent substrate on whole-plant corn silage and performance of lactating goats.

Pleurotus ostreatus (oyster mushroom) synthesizes enzymes that degrade lignin, cellulose, and hemicellulose. The objectives of this study were to evaluate the effect of Pleurotus ostreatus spent substrate (POSS) on whole-plant corn silage (WPCS) chemical composition, antioxidant capacity, lignin monomers, and in vitro….

Shiitake · 2021 · Randomized Controlled Trial · European journal of nutrition

Modulation of human intestinal microbiota in a clinical trial by consumption of a β-D-glucan-enriched extract obtained from Lentinula edodes.

PURPOSE: The aim of this study was to evaluate the hypocholesterolemic, immune- and microbiota-modulatory effect of a mushroom extract in hypercholesterolemic subjects..

Shiitake · 2015 · Randomized Controlled Trial · Journal of the American College of Nutrition

Consuming Lentinula edodes (Shiitake) Mushrooms Daily Improves Human Immunity: A Randomized Dietary Intervention in Healthy Young Adults.

BACKGROUND: Mushrooms are widely cited for their medicinal qualities, yet very few human intervention studies have been done using contemporary guidelines. OBJECTIVE: The aim of this study was to determine whether consumption of whole, dried Lentinula edodes (shiitake) mushrooms could improve human immune function..

Cordyceps · 2026 · Journal Article · Probiotics and antimicrobial proteins

Cordyceps Militaris Exopolysaccharides and Lactiplantibacillus Plantarum H8 Synergistically Improve Immune Function Damage in Cyclophosphamide-Induced Immunosuppressed Mice.

Metadata-grounded summary: This journal article indexes research on Cordyceps militaris in Probiotics and antimicrobial proteins in 2026. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

King Oyster · 2025 · Journal Article · Mokuzai Gakkaishi

Factors Affecting Mycelial Growth of New Variety Pleurotus eryngii × Pleurotus nebrodensis named ON206

Metadata-grounded summary: This journal article indexes research on Pleurotus eryngii in Mokuzai Gakkaishi in 2025. MycoData maps the paper to gut & microbiome based on its title, species context, article metadata, and study classification..

Shiitake · 2024 · Journal Article · Journal of the Japanese Forest Society

Effects of Inter- and Intra-tree Variations in 137Cs and K Concentrations of Konara Oak (Quercus serrata) on the 137Cs Transfer to Log-grown Shiitake Mushrooms (Lentinula edodes)

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in Journal of the Japanese Forest Society in 2024. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

Oyster Mushroom · 2024 · Research Article · Frontiers in microbiology

Effects of spent substrate of oyster mushroom (Pleurotus ostreatus) on ruminal fermentation, microbial community and growth performance in Hu sheep.

INTRODUCTION: The study aimed to evaluate the effects of Pleurotus Spent Mushroom Substrate (P.SMS) on the rumen microbiota, encompassing bacteria and fungi, as well as their interactions in Hu sheep. METHODS: A total of forty-five 3-month-old Hu sheep were randomly assigned to five groups..

Cordyceps · 2024 · Journal Article · International journal of biological macromolecules

Elucidation of antioxidant activities of intracellular and extracellular polysaccharides from Cordyceps militaris in vitro and their protective effects on ulcerative colitis in vivo.

In this study, we extracted the polysaccharides from C. militaris fruiting bodies (CFIPs), mycelial intracellular polysaccharides (CMIPs), and fermentation broth extracellular polysaccharides (CFEPs) to investigate their physicochemical properties, antioxidant capacities, and effects on oxazolone-induced zebrafish….

Shiitake · 2024 · Journal Article · Journal for the Integrated Study of Dietary Habits

Evaluation of flavor components of shiitake mushroom (Lentinula edodes (Berk.) Pegler) by low-temperature cooking

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in Journal for the Integrated Study of Dietary Habits in 2024. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

Shiitake · 2024 · Journal Article · Mushroom Science and Biotechnology

Mapping of quantitative trait loci associated with temperature for fruiting body induction in Lentinula edodes (Shiitake mushroom)

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in Mushroom Science and Biotechnology in 2024. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

OncologyImmune supportMetabolic healthGut & microbiome

Reishi · 2023 · Systematic Review · Food & function

Therapeutic potential and nutritional significance of Ganoderma lucidum - a comprehensive review from 2010 to 2022.

With a long history in traditional Asian medicine, Ganoderma lucidum (G. lucidum) is a mushroom species suggested to improve health and extend life.

Enoki · 2026 · Review · Journal of the science of food and agriculture

Biological activities and bioactive constituents of Flammulina velutipes: An updated systematic review.

Flammulina velutipes (enokitake) is an edible mushroom recognized for both its nutritional and medicinal properties. It exhibits a broad spectrum of biological activities, including antioxidant, anti-inflammatory, antitumor, immunomodulatory, and gut microbiota-regulating effects..

Immune supportCognition & nervesGut & microbiome

Reishi · 2026 · Review · International journal of biological macromolecules

Ganoderma lucidum polysaccharides target the gut-brain axis: Unveiling a novel mechanism for ameliorating aging-induced cognitive impairment and oxidative stress.

With the rapid progression of global population aging, the incidence of cognitive dysfunction-related disorders is steadily increasing. In recent years, growing attention has been directed toward the interaction between the gut microbiota and the central nervous system (CNS)..

Immune supportEnergy & fatigueGut & microbiome

Chaga · 2026 · Review · International journal of biological macromolecules

Preparation, bioactivities, structure-activity relationships, applications, and safety concerns of Inonotus obliquus polysaccharides: A review.

Inonotus obliquus polysaccharides (IOPs) are β-glucan-rich heteropolysaccharides whose structural diversity underlies their immunomodulatory, antioxidant, and gut-organ-axis-mediated activities..

OncologyImmune supportMetabolic healthGut & microbiome

Lion's Mane · 2025 · Review · Frontiers in nutrition

Advances in the extraction, purification, structural characterization, and elucidation of the biological functions of polysaccharides from Hericium erinaceus.

Hericium erinaceus has a high food and ornamental value and considerable benefits upon consumption and in research. The high polysaccharide content in H.

Energy & fatigueMetabolic healthGut & microbiomeSkin & hydration

Shiitake · 2025 · Review · Applied microbiology and biotechnology

Cultivation methods and biology of Lentinula edodes.

In this study, the biological applications of cultivation methods related to cultivar selection, vegetative growth, and reproductive development in Lentinula edodes cultivation are briefly reviewed to clarify the current situation and inform future developments..

OncologyImmune supportCognition & nervesGut & microbiome

Lion's Mane · 2025 · Review · International journal of biological macromolecules

Extraction, purification, structural characteristics, biological activities, modifications, and applications from Hericium erinaceus polysaccharides: A review.

Hericium erinaceus (Bull.) Pers. is a respected medicinal and edible fungus known for its outstanding nutritional profile.

Lion's Mane · 2025 · Review · Food science & nutrition

Extraction, Structural Characterization and Biological Activities of Polysaccharides Derived From Hericium erinaceus.

Hericium erinaceus is acknowledged for its dual roles in medicinal and culinary contexts. The polysaccharides derived from H.

Oyster Mushroom · 2025 · Randomized Controlled Trial, Veterinary · Animal science journal = Nihon chikusan Gakkaiho

In Vivo and In Vitro Digestibility and Fermentation Characteristics of Spent Mushroom Substrate (Pleurotus ostreatus) as a Feed Resource for Small Ruminants.

This study evaluated the nutritional value of spent mushroom substrate (SMS) supplemented with 4% urea and 18% molasses as a partial roughage replacement in small ruminant diets..

Shiitake · 2025 · Review · International journal of molecular sciences

Lentinula edodes as a Source of Bioactive Compounds with Therapeutical Potential in Intestinal Inflammation and Colorectal Cancer.

Inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), is a rising global health issue. Chronic intestinal inflammation is an important risk factor for colorectal cancer (CRC)..

Immune supportCognition & nervesGut & microbiomeLiver support

Lion's Mane · 2025 · Review · International journal of biological macromolecules

Recent insights into Hericium erinaceus polysaccharides: Gastrointestinal, gut microbiota, microbial metabolites, overall health and structure-function correlation.

Hericium erinaceus polysaccharides (HEPs) have attracted significant interest due to their potential to support gastrointestinal health and modulate gut microbiota..

Immune supportCognition & nervesGut & microbiome

Lion's Mane · 2025 · Review · Psychopharmacology bulletin

Theoretical Potential of Hericium Erinaceus Supplementation as an Add-On to Antipsychotics in Chronic and Treatment-Resistant Schizophrenia.

Schizophrenia is a serious mental illness that is a leading cause of disability worldwide. While antipsychotic agents are the most effective medications, up to one-third of patients experience treatment resistance, and approximately one-sixth of patients experience ultra-resistant illness..

OncologyImmune supportMetabolic healthGut & microbiome

Almond Mushroom · 2024 · Review · Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

[Research progress on structures, activities, and biosynthesis of blazeispirol compounds from Agaricus blazei].

Agaricus blazei is a rare medicinal and edible fungus with a crispy taste and delicious flavor. Both fruiting body and mycelium are rich in polysaccharides, sterols, terpenoids, peptides, lipids, polyphenols, and other active ingredients, which have strong pharmacological activities such as anti-tumor, lipid-lowering,….

OncologyImmune supportMetabolic healthGut & microbiome

Reishi · 2024 · Review · Heliyon

Bioactivities and industrial standardization status of Ganoderma lucidum: A comprehensive review.

Ganoderma lucidum (GL) is a potent source of bioactive compounds with diverse nutritional and pharmacological benefits. Its popularity as a dietary supplement, herbal remedy, and wellness product is steadily on the rise..

OncologyImmune supportMetabolic healthGut & microbiome

Mesima · 2024 · Review · International journal of biological macromolecules

Phellinus linteus polysaccharides: A review on their preparation, structure-activity relationships, and drug delivery systems.

Phellinus linteus polysaccharides exhibit antitumor, immunomodulatory, anti-inflammatory, and antioxidant properties, mitigate insulin resistance, and enhance the diversity and abundance of gut microbiota. However, the bioactivities of P..

Reishi · 2024 · Review · Frontiers in microbiology

Regulatory effect of Ganoderma lucidum and its active components on gut flora in diseases.

Driven by the good developmental potential and favorable environment at this stage, Ganoderma lucidum is recognized as a precious large fungus with medicinal and nutritional health care values. Among them, polysaccharides, triterpenoids, oligosaccharides, trace elements, etc.

OncologyImmune supportMetabolic healthGut & microbiome

Cordyceps · 2024 · Review · Molecules (Basel, Switzerland)

Cordyceps Polysaccharides: A Review of Their Immunomodulatory Effects.

Cordyceps primarily consists of ascomycetes, a parasitic fungus that infects insects and arthropods. Recently, Cordyceps has been shown to manifest a diverse range of pharmacological activities, rendering it applicable for the treatment and mitigation of various diseases, such as diabetes, acute liver injury, and….

Turkey Tail · 2023 · Preprint · journal metadata

Comprehending and Domesticating of Wild Growing Turkey Tail Mushroom (Trametes versicolor) from Ethiopia on augmented agro-industrial byproducts

Abstract Despite being one of the most studied white-rot fungi, nothing has been done to discover and domesticate Ethiopia's high-yielding wild Trametes versicolor. Thus, this study was initiated to evaluate the growth performance of T.

Shiitake · 2023 · Preprint · journal metadata

Extracellular enzymes secreted in the mycelial block of Lentinula edodes during hyphal growth

Abstract Lentinula edodes (shiitake mushroom) is one of the most widely cultivated edible mushrooms and is primarily cultivated using sawdust medium. While there have been improvements in the cultivation technology, the mechanism of mycelial block cultivation, such as mycelial growth and enzymatic sawdust degradation,….

Lion's Mane · 2022 · Preprint · journal metadata

Effects of Polysaccharide from Hericium Erinaceus on Diarrhea Rats Induced by Lincomycin Hydrochloride: A Potential Treatment for Gut Microbiota Dysbiosis

Abstract In China, the fungus Hericium erinaceus is known as a healthy food crop which possesses digestive tract protection functionality. This research was focus on the effects of polysaccharides extracted from Hericium erinaceus (WHP) on rats with diarrhea induced by antibiotic, specifically on the shifts of gut….

Cordyceps · 2022 · Preprint · journal metadata

Genetic and phylogenetic features of the repetitive ITS copies in the Hirsutella sinensis genome and the genomically independent AT-biased Ophiocordyceps sinensis genotypes

It has been hypothesized that AT-biased genotypes of Ophiocordyceps sinensis are generated through repeat-induced point mutation (RIP) and coexist as permanently nonfunctional internal transcribed spacer (ITS) pseudogenes in the genome of Hirsutella sinensis (GC-biased Genotype #1 of O. sinensis )..