MycoData
Medicinal fungi research database
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Immune support
Immune modulation, polysaccharides, beta-glucans, and host-response studies.
Species records
Species record
Oyster Mushroom
Pleurotus ostreatus
- Studies
- 1,947
- Avg relevance
- 53
- Latest
- 2026
Species record
Reishi · Lingzhi
Ganoderma lucidum
- Studies
- 1,830
- Avg relevance
- 60
- Latest
- 2026
Species record
Turkey Tail · Yun Zhi
Trametes versicolor
- Studies
- 1,828
- Avg relevance
- 41
- Latest
- 2026
Species record
Shiitake · Hua Gu
Lentinula edodes
- Studies
- 1,766
- Avg relevance
- 60
- Latest
- 2026
Species record
Cordyceps · Scarlet Club
Cordyceps militaris
- Studies
- 1,635
- Avg relevance
- 67
- Latest
- 2026
Species record
Cordyceps · Caterpillar Fungus
Ophiocordyceps sinensis
- Studies
- 1,576
- Avg relevance
- 59
- Latest
- 2026
Species record
Almond Mushroom · ABM
Agaricus blazei
- Studies
- 1,441
- Avg relevance
- 54
- Latest
- 2026
Species record
Enoki · Winter Mushroom
Flammulina velutipes
- Studies
- 1,403
- Avg relevance
- 47
- Latest
- 2026
Species record
King Oyster · Eryngii
Pleurotus eryngii
- Studies
- 1,278
- Avg relevance
- 60
- Latest
- 2026
Species record
Maitake · Hen of the Woods
Grifola frondosa
- Studies
- 1,276
- Avg relevance
- 48
- Latest
- 2026
Species record
Snow Fungus · Silver Ear
Tremella fuciformis
- Studies
- 1,052
- Avg relevance
- 29
- Latest
- 2026
Species record
Lion's Mane · Yamabushitake
Hericium erinaceus
- Studies
- 862
- Avg relevance
- 67
- Latest
- 2026
Species record
Chaga
Inonotus obliquus
- Studies
- 738
- Avg relevance
- 65
- Latest
- 2026
Species record
Mesima · Sanghwang
Phellinus linteus
- Studies
- 722
- Avg relevance
- 58
- Latest
- 2026
Species record
Niu-Chang-Chih
Antrodia camphorata
- Studies
- 496
- Avg relevance
- 63
- Latest
- 2026
Species record
Nameko · Nametake
Pholiota microspora
- Studies
- 421
- Avg relevance
- 29
- Latest
- 2026
Species record
Yellow Morel
Morchella esculenta
- Studies
- 392
- Avg relevance
- 42
- Latest
- 2026
Species record
Zhu Ling · Umbrella Polypore
Polyporus umbellatus
- Studies
- 263
- Avg relevance
- 55
- Latest
- 2026
Species record
Wood Ear · Kikurage
Auricularia auricula-judae
- Studies
- 254
- Avg relevance
- 51
- Latest
- 2026
Species record
Agarikon · Quinine Conk
Fomitopsis officinalis
- Studies
- 47
- Avg relevance
- 55
- Latest
- 2026
Articles
7,168 results
Showing 2,051–2,100 of 7,168
Chaga · 2020 · Research Article · ACS omega
Cecal Butyrate (Not Propionate) Was Connected with Metabolism-Related Chemicals of Mice, Based on the Different Effects of the Two Inonotus obliquus Extracts on Obesity and Their Mechanisms.
Obesity is a metabolic disease and causes significant changes in host and gut microbial metabolite levels. However, little research has been done on the relationship between host and gut microbial metabolites..
Snow Fungus · 2020 · Journal Article · Carbohydrate polymers
Chain conformation and physicochemical properties of polysaccharide (glucuronoxylomannan) from Fruit Bodies of Tremella fuciformis
Based on its potential bioactivities and sustainable source, polysaccharide (glucuronoxylomannan) from fruit bodies of Tremella fuciformis (TFP) aroused attention in food, pharmaceutical and cosmetic industry. The present study aimed at revealing its chain conformational and physicochemical properties..
Snow Fungus · 2020 · Journal Article · Carbohydrate polymers
Chain conformation and physicochemical properties of polysaccharide (glucuronoxylomannan) from Fruit Bodies of Tremella fuciformis.
Based on its potential bioactivities and sustainable source, polysaccharide (glucuronoxylomannan) from fruit bodies of Tremella fuciformis (TFP) aroused attention in food, pharmaceutical and cosmetic industry. The present study aimed at revealing its chain conformational and physicochemical properties..
Lion's Mane · 2020 · Journal Article · International journal of biological macromolecules
Characterization of polysaccharides isolated from Hericium erinaceus and their protective effects on the DON-induced oxidative stress.
In this study, the structure characteristic of the Hericium erinaceus polysaccharide (HEP) was investigated using Fourier transformed infrared spectrometry (FT-IR), gas chromatography-mass spectrometry (GC-MS), gel permeation chromatography (GPC), methylation and nuclear magnetic resonance (NMR)..
Enoki · 2020 · Research Article · Microorganisms
Comparative Analysis of Carbohydrate Active Enzymes in the Flammulina velutipes var. lupinicola Genome.
The purpose of this study was to determine the genome sequence of Flammulina velutipes var. lupinicola based on next-generation sequencing (NGS) and to identify the genes encoding carbohydrate-active enzymes (CAZymes) in the genome..
Shiitake · 2020 · Research Article · PeerJ
Comparative phosphoproteome analysis to identify candidate phosphoproteins involved in blue light-induced brown film formation in Lentinula edodes.
Light plays an important role in the growth and differentiation of Lentinula edodes mycelia, and mycelial morphology is influenced by light wavelengths. The blue light-induced formation of brown film on the vegetative mycelial tissues of L.
Snow Fungus · 2020 · Journal Article · International journal of biological macromolecules
Degradation of Tremella fuciformis polysaccharide by a combined ultrasound and hydrogen peroxide treatment: Process parameters, structural characteristics, and antioxidant activities.
The degradation effect of ultrasound (US)/hydrogen peroxide (H2O2) on Tremella fuciformis polysaccharide (TFP) were studied. The main process parameters of degradation were evaluated and the structural changes and antioxidant activities of TFP before and after US/H2O2 were analyzed..
Chaga · 2020 · Journal Article · Applied biochemistry and biotechnology
Effect of Colloidal Metal Nanoparticles on Biomass, Polysaccharides, Flavonoids, and Melanin Accumulation in Medicinal Mushroom Inonotus obliquus (Ach.:Pers.) Pilát.
The article explores effect of colloidal nanoparticles (NPs) of Ag, Fe, and Mg metals on the growth activity of the medicinal mushroom Inonotus obliquus (Ach.:Pers.) Pilát and the synthesis of biologically active compounds (polysaccharides, flavonoids, and melanins)..
Oyster Mushroom · 2020 · Journal Article · Journal of the science of food and agriculture
Effect of cultivating Pleurotus ostreatus on substrates supplemented with herb residues on yield characteristics, substrates degradation, and fruiting bodies' properties.
BACKGROUND: Inappropriate disposal of herb residues in China has caused major problems for the immediate environment and to human safety. Here, three herb residues, compound Kushen injection (CKI), Qizhi Tongluo capsule (QTC), and Shenbai Shuxin capsule (SSC), were applied as substrates to corncob at various ratios….
Enoki · 2020 · Journal Article · Food & function
Effects of a β-type glycosidic polysaccharide from Flammulina velutipes on anti-inflammation and gut microbiota modulation in colitis mice.
Using the Flammulina velutipes polysaccharide (FVP) extracted from our previous study, herein, we investigated the improvement of this starch-free β-type glycosidic polysaccharide in alleviating dextran sodium sulfate-induced ulcerative colitis (UC) in mice..
Shiitake · 2020 · Journal Article · International journal of biological macromolecules
Effects of freeze drying and hot-air drying on the physicochemical properties and bioactivities of polysaccharides from Lentinula edodes.
Fresh Lentinula edodes were dried using two process technologies-freeze drying (FD) and hot-air drying (HD). The physicochemical, antioxidant and immunomodulatory properties of purified polysaccharides from dried L.
Lion's Mane · 2020 · Research Article · Evidence-based complementary and alternative medicine: eCAM
Effects of Hericium erinaceus Mycelium Extracts on the Functional Activity of Purinoceptors and Neuropathic Pain in Mice with L5 Spinal Nerve Ligation.
Neuropathic pain is a serious clinical problem that is difficult to treat. Purinoceptors (P2Rs) transduce pain perception from the peripheral to the central nervous system and play an important role in the transmission of neuropathic pain signals..
Oyster Mushroom · 2020 · Research Article · Evidence-based complementary and alternative medicine: eCAM
Efficacy of Pleuran (β-Glucan from Pleurotus ostreatus) in the Management of Herpes Simplex Virus Type 1 Infection.
One of the highly prevalent viral pathogens among children and adults causing infection, clinically presenting as herpes labialis, is herpes simplex virus type 1 (HSV-1). The long-term administration of acyclovir, a standard regimen for therapy against HSV-1 infections, can cause viral resistance against this drug..
Oyster Mushroom · 2020 · Journal Article · International journal of medicinal mushrooms
Ergosterol Peroxide Isolated from Oyster Medicinal Mushroom, Pleurotus ostreatus (Agaricomycetes), Potentially Induces Radiosensitivity in Cervical Cancer.
Every year, more than 500,000 new cases of cervical cancer are reported, making it the fourth leading cause of cancer globally. Although human papillomavirus (HPV) vaccines show promise as a protective measure, HPV-related cancers remain a public health problem since the vaccines, which are only specific to certain….
Turkey Tail · 2020 · Journal Article · Current microbiology
Extracellular and Intracellular Polysaccharide Extracts of Trametes versicolor Improve Lipid Profiles Via Serum Regulation of Lipid-Regulating Enzymes in Hyperlipidemic Mice.
Trametes versicolor extracts have been shown to have health-promoting benefits in hypercholesterolemia, obesity, hepatic steatosis, and cardiovascular disease. However, hypolipidemic or the anti-hyperlipidemic effects of polysaccharide extracts of T.
Almond Mushroom · 2020 · Research Article · BioMed research international
Genome Survey and Transcriptome Analysis on Mycelia and Primordia of Agaricus blazei.
Agaricus blazei, a type of edible straw-rotting mushroom with somewhat sweet taste and fragrance of almonds, has attracted considerable scientific and practical attention. High-throughput Illumina PE150 and PacBio RSII platform were employed to generate a genomic sequence..
Mesima · 2020 · Journal Article · International journal of biological macromolecules
Hepatoprotective effect of Phellinus linteus mycelia polysaccharide (PL-N1) against acetaminophen-induced liver injury in mouse.
Edible and medicinal fungi are one of the major sources for extraction and identification of polysaccharides, which are important biological response modifiers with notable antitumor, hepatoprotective effect and other pharmacological activities..
Maitake · 2020 · Journal Article · International journal of biological macromolecules
Hypoglycemic and hypolipidemic activities of Grifola frondosa polysaccharides and their relationships with the modulation of intestinal microflora in diabetic mice induced by high-fat diet and streptozotocin.
This study aimed to investigate the hypoglycemic and hypolipidemic activities of polysaccharides from Grifola frondosa (GFP) in diabetic mice induced by high-fat diet (HFD) and streptozotocin (STZ)..
Maitake · 2020 · Journal Article · International journal of biological macromolecules
Hypoglycemic and hypolipidemic mechanism of organic chromium derived from chelation of Grifola frondosa polysaccharide-chromium (III) and its modulation of intestinal microflora in high fat-diet and STZ-induced diabetic mice.
Polysaccharide from Grifola frondosa is an excellent metal-ion chelating agent owing to its distinctive structure and outstanding functional activities. Our previous research has successfully synthesized novel organic chromium derived from the chelation ofG.
Turkey Tail · 2020 · Research Article · 3 Biotech
In vitro bioactivity, antimicrobial and anti-inflammatory efficacy of modified solvent evaporation assisted Trametes versicolor extract.
In the present study, modified solvent evaporation assisted methanolic Trametes versicolor extract was evaluated for its antimicrobial and anti-inflammatory efficacy..
Wood Ear · 2020 · Journal Article · International journal of medicinal mushrooms
Influence of Nigerian Jelly Ear Culinary-Medicinal Mushroom, Auricularia auricula-judae (Agaricomycetes), on Humoral and Cellular Immunity.
The fruiting body of Auricularia auricula-judae has received attention in folk medicine due to its possible medicinal values. Therefore, this study evaluated the immunomodulatory effects of the hot aqueous extract (AAAJ) and the β-D-glucan-rich polysaccharide fraction of A..
Chaga · 2020 · Journal Article · International journal of biological macromolecules
Inonotus obliquus polysaccharide ameliorates impaired reproductive function caused by Toxoplasma gondii infection in male mice via regulating Nrf2-PI3K/AKT pathway.
This study was carried out to investigate the effects of Inonotus obliquus polysaccharide (IOP) on impaired reproductive function and its mechanisms in Toxoplasma gondii (T. gondii)-infected male mice..
Chaga · 2020 · Journal Article · International journal of biological macromolecules
Inonotus obliquus polysaccharide protects against adverse pregnancy caused by Toxoplasma gondii infection through regulating Th17/Treg balance via TLR4/NF-κB pathway.
The study aimed to explore the protective effects of Inonotus obliquus polysaccharide (IOP) on adverse pregnancy caused by Toxoplasma gondii (T. gondii) infection and discover its potential mechanisms in pregnant mice..
Lion's Mane · 2020 · Journal Article · International journal of biological macromolecules
Isolation and structural characterization of a novel polysaccharide from Hericium erinaceus fruiting bodies and its arrest of cell cycle at S-phage in colon cancer cells.
The fruiting body of Hericium erinaceus has been used to treat digestive system disorder-related diseases for over 2000 years in China. A novel polysaccharide, HEFP-2b, was obtained from H.
Zhu Ling · 2020 · Research Article · Frontiers in chemistry
Mechanisms of Macrophage Immunomodulatory Activity Induced by a New Polysaccharide Isolated From Polyporus umbellatus (Pers.) Fries.
Bladder cancer is one of the most malignant tumors closely associated with macrophage immune dysfunction. The Chinese medicine polyporus has shown excellent efficacy in treating bladder cancer, with minimal side effects.
Enoki · 2020 · Research Article · Foods (Basel, Switzerland)
Molecular Properties of Flammulina velutipes Polysaccharide-Whey Protein Isolate (WPI) Complexes via Noncovalent Interactions.
Whey protein isolate (WPI) has a variety of nutritional benefits. The stability of WPI beverages has attracted a large amount of attention.
Enoki · 2020 · Journal Article · Food and chemical toxicology: an international journal published for the British Industrial Biological Research Association
Multiple fingerprint and fingerprint-activity relationship for quality assessment of polysaccharides from Flammulina velutipes.
Polysaccharides are known as one of the most important bioactive compounds in Flammulina velutipes. However, there is no accurate and comprehensive assessment method to evaluate and authenticate F.
Lion's Mane · 2020 · Research Article · BMC complementary medicine and therapies
Neuroprotective effects of Hericium erinaceus (Bull.: Fr.) Pers. against high-dose corticosterone-induced oxidative stress in PC-12 cells.
BACKGROUND: Hericium erinaceus is a culinary and medicinal mushroom in Traditional Chinese Medicines. It has numerous pharmacological effects including immunomodulatory, anti-tumour, anti-microbial, anti-aging and stimulation of nerve growth factor (NGF) synthesis, but little is known about its potential role in….
Enoki · 2020 · Journal Article · Journal of the science of food and agriculture
O/W Pickering emulsions stabilized by Flammulina velutipes polysaccharide nanoparticles as a fat substitute: the effects of phase separation on emulsified sausage's techno-functional and sensory quality.
BACKGROUND: The application of Pickering emulsion stabilized by food-derived particles is of great interest in the food field, including meat processing. However, the creaming phenomenon is a thorny problem and may impact the resulting product quality..
Enoki · 2020 · Journal Article · Journal of the science of food and agriculture
O/W Pickering emulsions stabilized by Flammulina velutipes polysaccharide nanoparticles as a fat substitute: the effects of phase separation on emulsified sausage's techno‐functional and sensory quality
BACKGROUND: The application of Pickering emulsion stabilized by food‐derived particles is of great interest in the food field, including meat processing. However, the creaming phenomenon is a thorny problem and may impact the resulting product quality..
Oyster Mushroom · 2020 · Journal Article · Food chemistry
Obtaining extracts rich in antioxidant polysaccharides from the edible mushroom Pleurotus ostreatus using binary system with hot water and supercritical CO2.
Pleurotus ostreatus is an edible mushroom with pharmacological potential, due to its metabolites, mainly polysaccharides. On here, the development of a new methodology for the recovery of extract rich in antioxidant polysaccharide was reported..
Shiitake · 2020 · Journal Article · Food and Bioproducts Processing
Parametric characterization of the initial pH effect on the polysaccharides production by Lentinula edodes in submerged culture
Edible fungus Lentinula edodes (L. edodes) produces exo-polysaccharides (EPS), which have been obtained from submerged mycelia cultures.
Oyster Mushroom · 2020 · Journal Article · International journal of biological macromolecules
Physicochemical characterization and antitumor activity in vitro of a selenium polysaccharide from Pleurotus ostreatus.
Selenium-enriched polysaccharides have been gaining great attention for their antitumor activity in recent years. In this study, a novel selenium polysaccharide fraction (Se-POP-3) produced by Pleurotus ostreatus was characterized and its antitumor activity explored at cellular level..
Lion's Mane · 2020 · Journal Article · International journal of biological macromolecules
Pre-protective effect of polysaccharides purified from Hericium erinaceus against ethanol-induced gastric mucosal injury in rats.
The β-glucan H6PC20 (Mw: 2390 kDa) and α-heteropolysaccharide HPB-3 (Mw: 15 kDa) were purified from the fruiting body of Hericium erinaceus according to the previous methods..
Maitake · 2020 · Journal Article · Carbohydrate polymers
Preparation and activities of selenium polysaccharide from plant such as Grifola frondosa
Selenium polysaccharide is an organic selenium compound formed by the combination of polysaccharide and selenium. The biological activity of selenium polysaccharide from plant such as Grifola frondosa is generally higher than that of selenium and polysaccharide, and it is more easily absorbed and utilized by human….
Snow Fungus · 2020 · Journal Article · Journal of food biochemistry
Preparation, characterization, and cytokine‐stimulating activity of oligosaccharides from Tremella fuciformis Berk
The Tremella fuciformis Berk polysaccharides (TP) have significant cytokine‐stimulating activity and low oral bioavailability owing to their large molecular volume..
Zhu Ling · 2020 · Journal Article · International journal of biological macromolecules
Preparation, physicochemical characterization, and anti-proliferation of selenium nanoparticles stabilized by Polyporus umbellatus polysaccharide.
Selenium nanoparticles (SeNPs), a novel selenium form, have attracted worldwide attention due to their bioactivities and low toxicity. This study aimed to assess the physicochemical characterization, storage stability, and anti-proliferative activities of SeNPs stabilized by Polyporus umbellatus polysaccharide (PUP)..
Cordyceps · 2020 · Journal Article · International journal of medicinal mushrooms
Protection against X-Ray Irradiation Injury by Chinese Caterpillar Medicinal Mushroom Ophiocordyceps sinensis (Ascomycetes) Polysaccharides in Mice.
Polysaccharides are one of the main active ingredients of Ophiocordyceps sinensis, a traditional Chinese medicinal mushroom. In this study, we investigated the protective effect of O.
Niu-Chang-Chih · 2020 · Research Article · Nutrients
Protective Effect of Spore Powder of Antrodia camphorata ATCC 200183 on CCl4-Induced Liver Fibrosis in Mice.
Liver fibrosis is a pathological process with intrahepatic diffused deposition of the excess extracellular matrix, which leads to various chronic liver diseases. Drugs with high efficacy and low toxicity for liver fibrosis are still unavailable..
Mesima · 2020 · Research Article · Evidence-based complementary and alternative medicine: eCAM
Protective Effects of Phellinus linteus Mycelium on the Development of Osteoarthritis after Monosodium Iodoacetate Injection.
OBJECTIVE: The aim of this study was to identify the protective effects of Phellinus linteus mycelium (PLM) and its possible mechanisms in a model of monosodium iodoacetate- (MIA-) induced osteoarthritis (OA)..
Maitake · 2020 · Journal Article · International journal of biological macromolecules
Regulatory effect of Grifola frondosa extract rich in polysaccharides and organic acids on glycolipid metabolism and gut microbiota in rats.
The present study investigated the composition of water extract of Grifola frondosa (GFWE) and its regulatory effects on glycolipid metabolism and gut microbiota in rats..
Snow Fungus · 2020 · Journal Article · International journal of medicinal mushrooms
Structural Analysis and Antioxidant Activity of Extracellular Polysaccharides Extracted from Culinary-Medicinal White Jelly Mushroom Tremella fuciformis (Tremellomycetes) Conidium Cells.
Using Tremella fuciformis conidium cells for submerged fermentation is a cost-effective way to harvest bioactive compounds. In this study, we emphasized the structural and functional analysis of extracellular polysaccharides (EPS) extracted from T.
Maitake · 2020 · Journal Article · Journal of food biochemistry
The hypoglycemic and renal protective effects of Grifola frondosa polysaccharides in early diabetic nephropathy
Grifola frondosa is a basidiomycete polypore fungus. Polysaccharides from G.
Lion's Mane · 2020 · Research Article · Frontiers in nutrition
The Inhibitory Effects of Hericium erinaceus β-glucan on in vitro Starch Digestion.
β-glucan has attracted extensive attention due to its health promoting effects, such as lowering the blood sugar and lipids levels, and enhancing immunity. In this study, three different β-glucans (HEBG-1, HEBG-2, HEBG-3) were obtained from Hericium erinaceus by sodium hydroxide, β-1,3-glucanase and β-1,6-glucanase,….
Maitake · 2020 · Journal Article · Glycoconjugate journal
The preparation of a cold-water soluble polysaccharide from Grifola frondosa and its inhibitory effects on MKN-45 cells.
In this study, a novel water soluble polysaccharide (named GFP-4) was extracted from Grifola frondosa at 4 oC, and its preliminary structure and inhibitory effects on human gastric carcinoma MKN-45 cells through the Fas/FasL death receptor apoptosis pathway were investigated..
Maitake · 2020 · Journal Article · International journal of biological macromolecules
The role of Rho1 gene in the cell wall integrity and polysaccharides biosynthesis of the edible mushroom Grifola frondosa.
Grifola frondosa polysaccharides, especially β-glucans, showed the significant antitumor, hypoglycemic, and immune-stimulating activities. In the present study, a predominant regulatory subunit gfRho1p of β-1,3-glucan synthase in G..
Turkey Tail · 2020 · Research Article · Frontiers in bioengineering and biotechnology
The Secretome of Phanerochaete chrysosporium and Trametes versicolor Grown in Microcrystalline Cellulose and Use of the Enzymes for Hydrolysis of Lignocellulosic Materials.
The ability of white-rot fungi to degrade polysaccharides in lignified plant cell walls makes them a suitable reservoir for CAZyme prospects. However, to date, CAZymes from these species are barely studied, which limits their use in the set of choices for biomass conversion in modern biorefineries..
Maitake · 2020 · Journal Article · International journal of biological macromolecules
UDP-glucose pyrophosphorylase gene affects mycelia growth and polysaccharide synthesis of Grifola frondosa.
To elucidate potential roles of UDP-glucose pyrophosphorylase (UGP) in mycelial growth and polysaccharide synthesis of Grifola frondosa, a putative 2036-bp UDP-glucose pyrophosphorylase gene gfugp encoding a 53.17-kDa protein was cloned and re-annotated..
Oyster Mushroom · 2020 · Journal Article · Molecules (Basel, Switzerland)
Use of a Pleurotus ostreatus Complex Cell Wall Extract as Elicitor of Plant Defenses: From Greenhouse to Field Trial.
Fungi constitute an abundant source of natural polysaccharides, some of them harboring original structures which can induce responses in mammalian or plant cells. An alkaline extract from the edible mushroom Pleurotus ostreatus has been obtained and called Pleuran complex cell wall extract (CCWE)..
Zhu Ling · 2019 · Journal Article · Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
[Study on polysaccharide content and monosaccharide composition of Polyporus umbellatus from different production areas].
In order to provide scientific basics for exploitation and sufficient application of Polyporus umbellatus resources and study the monosaccharide composition of P. umbellatus polysaccharides,the anthrone-sulfuric acid method was applied to compare polysaccharide content of P.