MycoData

Abstract Pharmaceutical wastewater contains hazardous contaminants, including analgesics and anti-inflammatory drugs, which pose significant environmental and health risks. Conventional treatment methods are often costly and inefficient, necessitating sustainable alternatives..

Immune support

High relevance

Maitake · 2025 · Research Article · Mycoscience

Two-stage wood decay by Grifola frondosa.

In nature, only white-rot fungi can completely decompose wood biomass in the environmental carbon cycle. However, their degradation strategy is still unclear.

Immune support

High relevance

Chaga · 2025 · Journal Article · Food Biophysics

Ultrasound-Assisted Treatment from Inonotus obliquus Polysaccharides: Extraction Optimization, Structures and Antioxidant Activity

This study examined the effect of sonication conditions on the extraction rate of Inonotus obliquus polysaccharides (IOPs) through a single-factor experiment. Meanwhile, the Box-Behnken design was utilized to optimize the sonication-assisted extraction technology..

Immune supportSkin & hydration

High relevance

Reishi · 2025 · Review · Pharmaceutics

Unlocking the Potential of Ganoderma lucidum (Curtis): Botanical Overview, Therapeutic Applications, and Nanotechnological Advances.

Background:Ganoderma lucidum (GL), commonly known as the "Lingzhi" or "Reishi" mushroom, has long been recognized for its potential health benefits and medicinal properties in traditional Chinese medicine..

OncologyImmune support

High relevance

Reishi · 2025 · Review · 3 Biotech

Unlocking the therapeutic potential of bioactive compounds in Ganoderma lucidum: a new frontier in natural medicine.

Ganoderma lucidum (Reishi), a valued medicinal fungus used in traditional medicine for over 2000 years, has sparked widespread scientific attention due to its extensive range of bioactive ingredients and therapeutic promise in modern medicine. This study presents a detailed and up-to-date examination of G..

OncologyImmune supportCognition & nervesSkin & hydration

High relevance

Lion's Mane · 2025 · Review · Frontiers in pharmacology

Unveiling the role of erinacines in the neuroprotective effects of Hericium erinaceus: a systematic review in preclinical models.

The medicinal mushroom lion's mane (Hericium erinaceus) is suggested to have therapeutic potential for neurological disorders due to its neuroprotective and neurotrophic properties. Mycelia of H..

Immune supportCognition & nerves

High relevance

Lion's Mane · 2025 · Research Article · International journal of molecular sciences

Yamabushitake Mushroom (Hericium erinaceus (Bull.) Pers. 1797) Mycelium Improves Reproductive System Dysfunction in Male Rats Induced by Polystyrene Microplastics.

The use of plastic products has increased, leading to higher levels of plastic pollution, and it is becoming a major public health concern. Health risks-especially those related to reproductive system dysfunction caused by polystyrene microplastics (PS-MPs)-are emerging issues that require urgent attention..

Immune supportCognition & nerves

High relevance

Chaga · 2024 · Review · Heliyon

A brief overview of the medicinal and nutraceutical importance of Inonotus obliquus (chaga) mushrooms.

This literature review offers an extensive exploration of Chaga mushrooms (Inonotus obliquus), focusing on their phytochemical composition, health-promoting attributes, and mechanisms of action..

OncologyImmune supportMetabolic health

High relevance

Cordyceps · 2024 · Journal Article · Environmental science and pollution research international

A novel approach in valorization of spent mushroom substrate of Cordyceps militaris as in-feed antibiotics in Labeo rohita against Aeromonas hydrophila infection.

The study was carried out to investigate Cordyceps militaris spent mushroom substrate (CMSMS), a renewable biomass, for its effect on fish as an alternative source of in-feed antibiotics..

Immune supportMetabolic health

High relevance

Cordyceps · 2024 · Journal Article · Life sciences

A novel exosome-like nanovesicles from Cordyceps militaris potentiate immunomodulatory and anti-tumor effect by reprogramming macrophages.

AIMS: Fungi-derived exosome-like nanovesicles (ENs) are emerging as a highly promising class of nanoparticles, particularly noted for their cost-effective production. However, their impact on immune regulation and their potential as anti-tumor agents need further exploration..

OncologyImmune support

High relevance

Cordyceps · 2024 · Randomized Controlled Trial · Scientific reports

A randomized controlled clinical trial examining the effects of Cordyceps militaris beverage on the immune response in healthy adults.

Cordyceps militaris (L.) Link (C. militaris) contains various beneficial substances, including polysaccharides (galactomannan), nucleotides (adenosine and cordycepin), cordycepic acid, amino acids, and sterols (ergosterol and beta-sitosterol)..

Immune supportMetabolic healthLiver support

High relevance

Reishi · 2024 · Review · Foods (Basel, Switzerland)

A Review of Ganoderma lucidum Polysaccharide: Preparations, Structures, Physicochemical Properties and Application.

Ganoderma lucidum (GL) is a kind of edible fungus with various functions and a precious medicinal material with a long history. Ganoderma lucidum polysaccharide (GLP) is one of the main bioactive substances in GL, with anti-tumor, anti-oxidation, anti-cancer, and other biological activities..

OncologyImmune support

High relevance

Cordyceps · 2024 · Review · International journal of biological macromolecules

A review on polysaccharide biosynthesis in Cordyceps militaris.

Cordyceps militaris (C. militaris) is an edible parasitic fungus with medicinal properties.

OncologyImmune supportMetabolic health

High relevance

Cordyceps · 2024 · Systematic Review · International journal of biological macromolecules

A systematic review on polysaccharides from fermented Cordyceps sinensis: Advances in the preparation, structural characterization, bioactivities, structure-activity relationships.

Cordyceps sinensis (Berk.) Sacc. (Ophiocordyceps sinensis) is an edible and medicinal fungus used as a natural superior tonic.

OncologyImmune support

High relevance

Cordyceps · 2024 · Research Article · Heliyon

Adjuvant activity of cordycepin, a natural derivative of adenosine from Cordyceps militaris, on an inactivated rabies vaccine in an animal model.

Vaccination is the most feasible way of preventing rabies, an ancient zoonosis that remains a major public health concern globally. However, administration of inactivated rabies vaccination without adjuvants is always inefficient and necessitates four to five injections..

Immune supportCognition & nervesMetabolic healthRespiratory

High relevance

Cordyceps · 2024 · Review · Bioengineering (Basel, Switzerland)

Advancing Cordyceps militaris Industry: Gene Manipulation and Sustainable Biotechnological Strategies.

Cordyceps militaris is considered to be of great medicinal potential due to its remarkable pharmacological effects, safety, and edible characteristics. With the completion of the genome sequence and the advancement of efficient gene-editing technologies, coupled with the identification of gene functions in Cordyceps….

Immune support

High relevance

Almond Mushroom · 2024 · Research Article · International journal of molecular sciences

Anti-Photodamage Effect of Agaricus blazei Murill Polysaccharide on UVB-Damaged HaCaT Cells.

UVB radiation is known to induce photodamage to the skin, disrupt the skin barrier, elicit cutaneous inflammation, and accelerate the aging process. Agaricus blazei Murill (ABM) is an edible medicinal and nutritional fungus..

OncologyImmune supportEnergy & fatigueSkin & hydration

High relevance

King Oyster · 2024 · Journal Article · International journal of biological macromolecules

Antibacterial and hemostatic chitin sponge directly constructed from Pleurotus Eryngii via top-down approach.

Chitin, the second most abundant polysaccharide on earth, possesses unique characteristics, including biosafety, biodegradability, and procoagulant activity, making it an attractive material for hemostasis. However, the conventional bottom-up construction of chitin-based materials is intricate and time-consuming..

Immune supportCognition & nervesLiver supportSkin & hydration

High relevance

Oyster Mushroom · 2024 · Research Article · Frontiers in nutrition

Antioxidant capacities and non-volatile metabolites changes after solid-state fermentation of soybean using oyster mushroom (Pleurotus ostreatus) mycelium.

Given the abundance of beneficial properties and enzymes secreted by edible oyster mushrooms, their mycelium could serve as a starter for fermented foods to enhance their nutritional and bioactive quality..

Immune supportEnergy & fatigue

High relevance

Chaga · 2024 · Research Article · Biomolecules

Chaga Mushroom Triterpenoids Inhibit Dihydrofolate Reductase and Act Synergistically with Conventional Therapies in Breast Cancer.

Inonotus obliquus (Chaga) is a medicinal mushroom with several pharmacological properties that is used as a tea in traditional Chinese medicine. In this study, Chaga water extract was digested in vitro to mimic the natural processing and absorption of its biocomponents when it is consumed as functional beverage, and….

OncologyImmune supportGut & microbiome

High relevance

Cordyceps · 2024 · Journal Article · Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire

Changes in aggregation properties and the metabolite production of probiotics following treatment with polysaccharides derived from the edible mushroom Cordyceps militaris

Low-molecular-weight exopolysaccharides of Cordyceps militaris (LCMP), obtained by enzymatically digesting the exopolysaccharide produced by C. militaris, were purified and found to be comprised of 77.9% mannose and 22.1% glucose..

OncologyImmune supportMetabolic healthGut & microbiome

High relevance

King Oyster · 2024 · Journal Article · Journal of food composition and analysis

Characterization of two Tunisian strains of culinary oyster mushroom Pleurotus eryngii: Differences in the biopolymer composition

Two Tunissian strains of oyster mushrooms, identified as Pleurotus eryngii var. elaeoselini and var.

Immune support

High relevance

Cordyceps · 2024 · Research Article · Pharmaceuticals (Basel, Switzerland)

Coffee with Cordyceps militaris and Hericium erinaceus Fruiting Bodies as a Source of Essential Bioactive Substances.

Drinking coffee is a daily routine for many people. Supplement manufacturers have proposed adding powdered Cordyceps militaris, known for its ergogenic and immunostimulating properties, and Hericium erinaceus, known for its nerve growth factor (NGF)-stimulating properties, to coffee..

Immune supportCognition & nerves

High relevance

Oyster Mushroom · 2024 · Research Article · Journal of fungi (Basel, Switzerland)

Comparative Analysis of Freeze-Dried Pleurotus ostreatus Mushroom Powders on Probiotic and Harmful Bacteria and Its Bioactive Compounds.

Pleurotus ostreatus (oyster mushroom) holds excellent promise worldwide, bringing several opportunities and augmenting the tool sets used in the biotechnology field, the food industry, and medicine. Our study explores the antimicrobial and probiotic growth stimulation benefits of freeze-dried P..

Immune supportGut & microbiomeSkin & hydration

High relevance

Enoki · 2024 · Journal Article · Journal of food composition and analysis

Comparative Assessment of β-glucan Composition and Structural Characterization in Wild and Commercial Enoki Mushrooms, Flammulina velutipes

This study investigated the β-glucan content and structure in an indigenous Enoki mushroom compared with a European commercial strain. Both Enoki types belonged to the same species, Flammulina velutipes, and grew on the same substrate..

Immune supportEnergy & fatigue

High relevance

Enoki · 2024 · Journal Article · International journal of biological macromolecules

Comprehensive evaluation of Flammulina velutipes residues polysaccharide based on in vitro digestion and human fecal fermentation.

Flammulina velutipes residues (FVR) are the waste culture medium derived from the collection of Flammulina velutipes fruiting bodies, with an annual output that remains largely unexplored..

Immune supportGut & microbiome

High relevance

Oyster Mushroom · 2024 · Research Article · Frontiers in microbiology

Contrasting effects of NADPH oxidases on the fungal hyphae growth and immune responses in Pleurotus ostreatus.

Pleurotus ostreatus is one of the most consumed mushroom species, as it serves as a high-quality food, favors a rich secondary metabolism, and has remarkable adaptability to the environment and predators..

Immune supportEnergy & fatigue

High relevance

Cordyceps · 2024 · Research Article · Antioxidants (Basel, Switzerland)

Cordyceps militaris Extract and Cordycepin Alleviate Oxidative Stress, Modulate Gut Microbiota and Ameliorate Intestinal Damage in LPS-Induced Piglets.

Cordycepin is considered a major bioactive component in Cordyceps militaris extract. This study was performed to evaluate the ameliorative effect of Cordyceps militaris extract (CME) and cordycepin (CPN) supplementation on intestinal damage in LPS-challenged piglets..

Immune supportGut & microbiome

High relevance

Cordyceps · 2024 · Journal Article · Molecular immunology

Cordyceps militaris fruit body activates myeloid dendritic cells via a Dectin-1-mediated pathway.

Cordyceps militaris, an entomopathogenic fungus, has been traditionally used in East Asian medicine. Recent research indicates that the fruit bodies of C.

Immune support

High relevance

Cordyceps · 2024 · Research Article · International journal of molecular sciences

Cordyceps militaris Grown on Germinated Rhynchosia nulubilis (GRC) Encapsulated in Chitosan Nanoparticle (GCN) Suppresses Particulate Matter (PM)-Induced Lung Inflammation in Mice.

Cordyceps militaris grown on germinated Rhynchosia nulubilis (GRC) exerts various biological effects, including anti-allergic, anti-inflammatory, and immune-regulatory effects..

Immune supportGut & microbiomeRespiratory

High relevance

Cordyceps · 2024 · Research Article · Frontiers in microbiology

Discovering a novel glycosyltransferase gene CmUGT1 enhances main metabolites production of Cordyceps militaris.

Cordyceps militaris is a filamentous fungus used for both medicinal and culinary purposes. It exhibits a wide range of pharmacological activities due to its valuable contents of cordycepin, polysaccharides, carotenoids, terpenoids and other metabolites.

Immune support

High relevance

Cordyceps · 2024 · Research Article · Journal of animal science

Effect of cordyceps militaris on growth performance, antioxidant capacity, and intestinal epithelium functions in weaned pigs.

To explore the effects of cordyceps militaris (CM) on growth performance and intestinal epithelium functions, 180 weaned pigs were randomly assigned into 5 treatments with 6 replicate pens per treatment (6 pigs per pen)..

Immune supportEnergy & fatigueGut & microbiome

High relevance

Enoki · 2024 · Research Article · Scientific reports

Effect of Flammulina velutipes polysaccharide on mitochondrial apoptosis in lung adenocarcinoma A549 cells.

FVP is a polysaccharide extracted from Flammulina velutipes with immunomodulatory, anti-tumor, and anti-oxidation activities. In this study, we obtained the crude polysaccharide FVP-C from the water extract of Flammulina velutipes, and its main component FVP-S1 was obtained after further purification..

OncologyImmune supportEnergy & fatigueMetabolic health

High relevance

Oyster Mushroom · 2024 · Journal Article · International dairy journal

Effect of polysaccharide fraction from oyster mushroom (Pleurotus ostreatus) on physicochemical and antioxidative properties of acid casein model processed cheese

The effect of polysaccharide fraction from oyster mushroom (POM) on texture, rheological and melting properties, density, water activity, colour, and antioxidative properties of acid casein model processed cheese was investigated. The samples were tested after 24 h and 21 days of cold storage..

Immune support

High relevance

Cordyceps · 2024 · Systematic Review · Frontiers in pharmacology

Effects and safety of Ophiocordyceps sinensis preparation in the adjuvant treatment for dialysis patients: a systematic review and meta-analysis.

ETHNOPHARMACOLOGICAL RELEVANCE: Ophiocordyceps sinensis (O. sinensis), a genus of ascomycete fungi, has been widedly used in China as a dietary supplement or natural remedy and intensively studied in various disease models with its immunomodulatory potentials..

Immune support

High relevance

Wood Ear · 2024 · Journal Article · Phytomedicine: international journal of phytotherapy and phytopharmacology

Effects of Auricularia auricula-judae (Bull.) Quél. polysaccharide acid hydrolysate on glucose metabolism in diabetic mice under oxidative stress.

BACKGROUND: Oxidative stress can lead to uncontrolled glucose metabolism and, thus, diabetes. Auricularia auricula-judae (Bull.) Quél.

Immune supportEnergy & fatigueMetabolic health

High relevance

Reishi · 2024 · Journal Article · Aquaculture

Effects of dietary reishi mushroom (Ganoderma lucidum) on the growth performance of Nile tilapia, Oreochromis niloticus juveniles

In aquaculture, several medicinal mushrooms have been successfully used as prebiotics, with attractive growth-stimulant, immune-modulatory, and antioxidant functions for several finfish species..

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

High relevance

King Oyster · 2024 · Journal Article · International journal of biological macromolecules

Effects of different selenium biofortification methods on Pleurotus eryngii polysaccharides: Structural characteristics, antioxidant activity and binding capacity in vitro.

The effects of selenium biofortification methods involving sodium selenite and selenium yeast on the structural characteristics, antioxidant activity and binding capacity of Pleurotus eryngii polysaccharides were investigated..

Immune support

High relevance

Reishi · 2024 · Randomized Controlled Trial, Veterinary · Animal biotechnology

Effects of JUNCAO Ganoderma lucidum polysaccharide peptide on slaughter performance and intestinal health of Minxinan black rabbits.

This experiment was conducted to investigate the effects of JUNCAO Ganoderma lucidum polysaccharide peptide (JCGLPP) on slaughter performance and intestinal health of Minxinan black rabbits, which aimed to provide the basis for the application of JCGLPP in meat rabbits..

Immune supportEnergy & fatigueGut & microbiome

High relevance

King Oyster · 2024 · Journal Article · Journal of food composition and analysis

Effects of microwave power control on enzyme activity, drying kinetics, and typical nutrients of Pleurotus Eryngii: Exploring the blanching mechanism by microstructural and ultrastructural evaluation

A Penetrating Microwave Infrared Hot-Air Rolling-Bed Dryer (PMIHRBD) was developed for penetrating microwave blanching (PMB) of pleurotus eryngii. The effects of PMB pretreatment on enzyme activity, drying kinetics and typical nutrients constituents were investigated at different power levels (1–3 W/g) and….

Immune support

High relevance

Mesima · 2024 · Preprint · journal metadata

Effects of tyndallized lactic acid bacteria separated from Phellinus linteus on inflammation and skin barrier damage induced by DNCB

Abstract Background The fruiting bodies of the Sanghwang mushroom ( Phellinus linteus ) have a long history of use in folk medicine throughout Asia, particularly in Korea, Japan, and China. However, research on the Sanghwang mushroom is still at an early stage..

Immune supportSkin & hydration

High relevance

Cordyceps · 2024 · Journal Article · Journal of basic microbiology

Enhanced polysaccharide production through quorum sensing system in Cordyceps militaris.

This study aimed to enhance extracellular polysaccharide (EPS) production in Cordyceps militaris by constructing a quorum sensing (QS) system to regulate the expression of biosynthetic enzyme genes, including phosphoglucomutase, hexokinase, phosphomannomutase, polysaccharide synthase, and UDP-glucose 4-epimerase….

Immune supportMetabolic health

High relevance

Cordyceps · 2024 · Research Article · Scientific reports

Enhancing cancer immunotherapy using cordycepin and Cordyceps militaris extract to sensitize cancer cells and modulate immune responses.

Integrating immunotherapy with natural compounds holds promise in enhancing the immune system's ability to eliminate cancer cells. Cordyceps militaris, a traditional Chinese medicine, emerges as a promising candidate in this regard.

OncologyImmune supportLiver support

High relevance

Cordyceps · 2024 · Journal Article · Journal of biomolecular structure & dynamics

Evaluation of Cordyceps militaris steroids as anti-inflammatory agents to combat the Covid-19 cytokine storm: a bioinformatics and structure-based drug designing approach.

Since the SARS-CoV-2 epidemic, researchers have been working on figuring out ways to tackle multi-organ failure and hyperinflation, which are brought on by a cytokine storm..

Immune supportEnergy & fatigueMetabolic healthRespiratory

High relevance

King Oyster · 2024 · Research Article · Nutrients

Evaluation of Physicochemical Properties and Prebiotics Function of a Bioactive Pleurotus eryngii Aqueous Extract Powder Obtained by Spray Drying.

A bioactive Pleurotus eryngii aqueous extract powder (SPAE) was obtained by spray drying and its performance in terms of physicochemical properties, in vitro digestion, inflammatory factors, and modulation of the intestinal microbiota was explored..

Immune supportEnergy & fatigueGut & microbiome

High relevance

Oyster Mushroom · 2024 · Research Article · Current issues in molecular biology

Evaluation of the Influence of Varied Juncao Grass Substrates on Physiological and Enzymatic Reactions of Pleurotus ostreatus.

Pleurotus ostreutus is one of the world's most commonly consumed mushrooms. The cultivation of mushrooms using wood resources usually results in environmental issues such as deforestation..

Immune supportCognition & nerves

High relevance

Reishi · 2024 · Journal Article · Heliyon

Evaluation of the phytochemical, bioactive compounds and descriptive sensory of encapsulated lingzhi (Ganoderma lucidum) extracts with combined wall materials for masking effect on the perception of off-flavour and bitterness

Lingzhi mushroom (Ganoderma lucidum) is known as a medicinal mushroom that can be utilized in various functional foods available in the market, including powders, dietary supplements, and tea. However, its use is limited due to factors such as bitterness, flavour, and astringency..

Immune support

High relevance

Reishi · 2024 · Research Article · Heliyon

Evaluation of the phytochemical, bioactive compounds and descriptive sensory of encapsulated lingzhi (Ganoderma lucidum) extracts with combined wall materials for masking effect on the perception of off-flavour and bitterness.

Immune support

High relevance

Oyster Mushroom · 2024 · Research Article · Journal of pharmacy & bioallied sciences

Exploring the Role of Pleurotus Ostreatus as an Ointment Formulation in Inducing Wound Healing in Mice Skin.

BACKGROUND: Natural compounds rich in secondary metabolites have gained attention as alternative therapies for wound healing due to their potential advantages over conventional treatments..

Immune supportSkin & hydration

High relevance

Reishi · 2024 · Review · Journal of clinical medicine

Exploring the Therapeutic Potential of Ganoderma lucidum in Cancer.

Triterpenoids, such as ganoderic acid, and polysaccharides, including β-D-glucans, α-D-glucans, and α-D-mannans, are the main secondary metabolites of the medicinal fungus Ganoderma lucidum..

OncologyImmune supportEnergy & fatigue