MycoData

Grifola frondosa, an edible and medicinal resource, is widely used as functional foods worldwide. To explore bioactive compounds against α-glucosidase, human tumor cells and enterovirus 71 (EV71), eight compounds were isolated from G.

OncologyMetabolic healthRespiratory

High relevance

Turkey Tail · 2023 · Journal Article · Journal of biotechnology

Antifungal activity of simply fractionated organosolv lignin against Trametes versicolor.

In an effort to achieve sustainable development goals, a reevaluation of the materials used in wooden buildings must be done, including the preservatives used to treat the materials. Since typical wood preservatives use toxic heavy metals, their handling and use can contaminate the environment..

High relevance

Lion's Mane · 2023 · Research Article · Polymers

Antioxidant Activities and Prebiotic Activities of Water-Soluble, Alkali-Soluble Polysaccharides Extracted from the Fruiting Bodies of the Fungus Hericium erinaceus.

In this study, the digestion and fermentation properties of the bioactive water-soluble polysaccharide (HEP-W), and alkali-soluble polysaccharide (HEP-A) from Hericium erinaceus and the impact on the human colonic microbiota were determined using simulated saliva-gastrointestinal digestion and human fecal fermentation….

Immune supportGut & microbiome

High relevance

Turkey Tail · 2023 · Research Article · Journal of veterinary research

Antioxidant and antimicrobial properties of an extract rich in proteins obtained from Trametes versicolor.

INTRODUCTION: Bioactive proteins and peptides generated from fruit, vegetables, meat or fish have great potential as functional food or substitutes for antibiotics. In recent years it has also been demonstrated that the fungus kingdom could be a source of these compounds..

Skin & hydrationRespiratory

High relevance

Maitake · 2023 · Research Article · International journal of food science

Antioxidant and Immunomodulatory Activities of Polysaccharides from Fermented Wheat Products of Grifola frondosa: In Vitro Methods.

Despite the well-known health benefits of Grifola frondosa, there is a lack of understanding regarding the potential antioxidant and immunomodulatory properties of different varieties when fermented with wheat grains. We aimed to explore the potential of G.

OncologyImmune supportMetabolic health

High relevance

Yellow Morel · 2023 · Research Article · Foods (Basel, Switzerland)

Antioxidative and Protective Effect of Morchella esculenta against Dextran Sulfate Sodium-Induced Alterations in Liver.

Morchella esculenta is an edible mushroom with special flavor and high nutritional value for humans, primarily owing to its polysaccharide constituents. M.

Immune supportGut & microbiomeLiver support

High relevance

Reishi · 2023 · Research Article · Veterinary world

Antiprotozoal activity of Boesenbergia rotunda (L.) Mansf and Ganoderma lucidum (Fr.) Kart extracts against Blastocystis hominis.

BACKGROUND AND AIM: Blastocystis hominis is an intestinal protozoan in humans and animals. The parasite causes mild-to-severe intestinal complications, such as diarrhea, in healthy humans and immunocompromised hosts..

Immune supportGut & microbiome

High relevance

Reishi · 2023 · Research Article · Chinese journal of cancer research = Chung-kuo yen cheng yen chiu

Aqueous-soluble components of sporoderm-removed Ganoderma lucidum spore powder promote ferroptosis in oral squamous cell carcinoma.

OBJECTIVE: Ferroptosis is a novel cell death process which displays a promising role in cancer treatment. However, clinically available drugs targeting ferroptosis are rarely used, and yet there are no studies reporting on inducing ferroptosis via Chinese herbal extracts..

OncologyEnergy & fatigue

High relevance

Shiitake · 2023 · Journal Article · Animal feed science and technology

Assessing the nutritional quality of fungal treated wheat straw: Compounds formed after treatment with Ceriporiopsis subvermispora and Lentinula edodes

A variety of secondary metabolites are formed and compounds released during the bioconversion of lignocellulosic biomass by white-rot fungi that can affect the nutritional value and acceptance of the biomass by ruminants..

Energy & fatigue

High relevance

Wood Ear · 2023 · Journal Article · International journal of biological macromolecules

Auricularia auricula-judae (Bull.) polysaccharides improve obesity in mice by regulating gut microbiota and TLR4/JNK signaling pathway.

Obesity has emerged as a crucial factor impacting people's lives, and gut microbiota disorders contribute to its development and progression. Auricularia auricula-judae (Bull.) polysaccharides (AAPs), a traditional functional food in Asia, exhibit potential anti-obesity effects..

Immune supportMetabolic healthGut & microbiomeLiver support

High relevance

Reishi · 2023 · Research Article · Molecules (Basel, Switzerland)

Benzothiazole-An Antifungal Compound Derived from Medicinal Mushroom Ganoderma lucidum against Mango Anthracnose Pathogen Colletotrichum gloeosporioides (Penz and (Sacc.)).

The present investigation is focused on exploring the possibilities of identifying biomolecules from the fruiting body of the medicinal mushroom Ganoderma lucidum against the mango anthracnose pathogen Colletotrichum gloeosporioides. The fruiting body (cap and stipe portion) of G..

High relevance

Lion's Mane · 2023 · Journal Article · International journal of biological macromolecules

Biocatalytic characterization of Hericium erinaceus laccase isoenzymes for the oxidation of lignin derivative substrates.

Mushroom laccases are biocatalysts that oxidize various substrates. To identify a novel enzyme involved in lignin valorization, we isolated and characterized laccase isoenzymes from the mushroom Hericium erinaceus..

High relevance

Maitake · 2023 · Research Article · Biotechnology for biofuels and bioproducts

Biochemical and structural characterization of a glucan synthase GFGLS2 from edible fungus Grifola frondosa to synthesize β-1, 3-glucan.

BACKGROUND: Grifola frondosa is a Basidiomycete fungus belonging to the family of Grifolaceae and the order of Polyporales. β-Glucans are the main polymers in G.

Metabolic health

High relevance

Lion's Mane · 2023 · Journal Article · International journal of biological macromolecules

Biochemical characterization and cytotoxicity of polylactosamine-extended N-glycans binding isolectins from the mushroom Hericium erinaceus.

The mushroom Hericium erinaceus expresses isolectins with different glycan binding specificities; of these, the ricin B-like lectin HEL1 and HEL2 (HEL2a and HEL2b) can bind fucosylated N-glycans and core 1 O-glycans, respectively. However, other lectin-like protein-coding transcripts detected in the H..

Oncology

High relevance

Cordyceps · 2023 · Journal Article · Journal of ethnopharmacology

Bioinformatics analysis and in vivo validation study of Ophiocordyceps sinensis (Berk.)G.H.Sungetal against lung adenocarcinoma.

ETHNOPHARMACOLOGICAL RELEVANCE: Lung adenocarcinoma (LUAD) is one of the main types of lung cancer. Ophiocordyceps sinensis has many potentially useful pharmacologic features, such as lung protection, and both anti-inflammatory and antioxidant activities..

OncologyImmune supportRespiratory

High relevance

Turkey Tail · 2023 · Journal Article · Bioresource technology

Biotransformation of chloramphenicol by white-rot-fungi Trametes versicolor under cadmium stress.

The recalcitrant chloramphenicol (CAP) combined with heavy metals cadmium (Cd) commonly co-existed in the environment, posing threat to environment health. The capacity of Trametes versicolor to remove/biodegrade CAP in air-pulse fluidized-bed reactor was evaluated, even under Cd stress.

High relevance

Oyster Mushroom · 2023 · Research Article · Biomimetics (Basel, Switzerland)

Biowelding 3D-Printed Biodigital Brick of Seashell-Based Biocomposite by Pleurotus ostreatus Mycelium.

Mycelium biocomposites are eco-friendly, cheap, easy to produce, and have competitive mechanical properties. However, their integration in the built environment as durable and long-lasting materials is not solved yet..

Energy & fatigueMetabolic healthLiver support

High relevance

Oyster Mushroom · 2023 · Journal Article · Mycologia

Cauliflower-shaped Pleurotus ostreatus cultivated in an atmosphere with high environmental carbon dioxide concentration.

Commercial aspects, physiological properties, and nutritional characteristics of Pleurotus ostreatus grown under various environmental carbon dioxide concentration ([CO2]e) conditions were assessed..

High relevance

Yellow Morel · 2023 · Journal Article · Ying yong sheng tai xue bao = The journal of applied ecology

Characteristics and risk assessment of chilling injury on Morchella esculenta in Western Sichuan Plateau, China.

The development of precise climate risk zoning for chilling injury of Morchella esculenta can provide scientific basis for agricultural cultivation planning, dynamic assessment of chilling injury, and disaster prevention strategies..

High relevance

Cordyceps · 2023 · Research Article · International journal of molecular sciences

Characterization and Biological Activities of Melanin from the Medicinal Fungi Ophiocordyceps sinensis.

Melanin is a complex natural pigment that is widely present in fungi. The mushroom Ophiocordyceps sinensis has a variety of pharmacological effects.

Energy & fatigueSkin & hydration

High relevance

Niu-Chang-Chih · 2023 · Journal Article · Journal of agricultural and food chemistry

Characterization of Cinnamomum kanehirae Extract-Stimulated Triterpenoids Synthesis in Submerged Fermentation of Antrodia camphorata via Untargeted Metabolomics.

The underlying mechanisms of Cinnamomum kanehirae-stimulated growth and metabolism of Antrodia camphorata remain unknown. Herein, we first observed that the methanol extract of C.

High relevance

Turkey Tail · 2023 · Research Article · Pharmaceuticals (Basel, Switzerland)

Characterization, In Vitro Biological Activity and In Vivo Cardioprotective Properties of Trametes versicolor (L.:Fr.) Quél. Heteropolysaccharides in a Rat Model of Metabolic Syndrome.

The present study aimed to examine the biological activity and cardioprotective potential of Trametes versicolor heteropolysaccharides (TVH) in a rat model of metabolic syndrome (MetS)..

Immune supportMetabolic health

High relevance

Reishi · 2023 · Research Article · Life (Basel, Switzerland)

Chemical Characterization and Evaluation of Antimicrobial Properties of the Wild Medicinal Mushroom Ganoderma lucidum Growing in Northern Moroccan Forests.

Ganoderma lucidum is an extensively famous medicinal mushroom distributed worldwide. Despite being widely grown in Moroccan forests, there are no studies on its nutritional, nutraceutical and pharmaceutical values..

Skin & hydration

High relevance

Reishi · 2023 · Research Article · Plants (Basel, Switzerland)

Chemical Constituents and Antimicrobial Activity of a Ganoderma lucidum (Curtis.) P. Karst. Aqueous Ammonia Extract.

Mushroom extracts have shown potential as a source of new antimicrobial agents. This study investigates the chemical profile of an aqueous ammonia extract obtained from the carpophores of Ganoderma lucidum, which grows on Quercus ilex trees, and explores its valorization as a biorational..

High relevance

Niu-Chang-Chih · 2023 · Journal Article · Natural product research

Chemical investigations and cytotoxic effects of metabolites from Antrodia camphorata against human hepatocellular carcinoma cells.

Antrodia camphorata is used as a medicinal fungus in Taiwan to treat fatigue, food intoxication, and enhance liver function. Here we identified fermented metabolic components from the mycelium of A.

OncologyEnergy & fatigueMetabolic healthLiver support

High relevance

Oyster Mushroom · 2023 · Research Article · Journal of fungi (Basel, Switzerland)

Co-Culture of White Rot Fungi Pleurotus ostreatus P5 and Bacillus amyloliquefaciens B2: A Strategy to Enhance Lipopeptide Production and Suppress of Fusarium Wilt of Cucumber.

Fusarium wilt, caused by Fusarium oxysporum f. sp.

Metabolic health

High relevance

Lion's Mane · 2023 · Research Article · Biology

Cognitive Healthy Aging in Mice: Boosting Memory by an Ergothioneine-Rich Hericium erinaceus Primordium Extract.

Brain aging is a crucial risk factor for several neurodegenerative disorders and dementia. The most affected cognitive function is memory, worsening early during aging..

Immune supportCognition & nervesSkin & hydration

High relevance

Reishi · 2023 · Journal Article · Food & function

Combined Ganoderma lucidum polysaccharide and ciprofloxacin therapy alleviates Salmonella enterica infection, protects the intestinal barrier, and regulates gut microbiota.

Clinical antibiotics used worldwide could diminish the intestinal barrier, enhance contact with microbiota and intestinal immune cells, and induce inflammation. We found that ciprofloxacin treatment of Salmonella enterica serovar Typhimurium infection resulted in the destruction of the intestinal barrier, with….

Immune supportGut & microbiome

High relevance

Turkey Tail · 2023 · Journal Article · Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire

Combined use of Trametes versicolor extract and sourdough fermentation to extend the microbiological shelf-life of baked goods

Fungal spoilage is the main responsible for the short shelf-life of baked goods. Indeed, many chemical preservatives (e.g., calcium propionate and ethanol) are often included in their formulation leading to consumer dissatisfaction..

Energy & fatigue

High relevance

Shiitake · 2023 · Research Article · Frontiers in microbiology

Comparative analysis of simulated in-situ colonization and degradation by Lentinula edodes on oak wafer and corn stalk.

INTRODUCTION: The depolymerization of lignocellulose biomass by white-rot fungi has been an important research topic. However, few simulated in-situ analyses have been conducted to uncover the decay..

Immune supportEnergy & fatigueGut & microbiome

High relevance

Oyster Mushroom · 2023 · Journal Article · Journal of biomolecular structure & dynamics

Comparative homology of Pleurotus ostreatus laccase enzyme: Swiss model or Modeller?

Laccases stand out in the industrial context due to their versatile biotechnological applications. Although these enzymes are frequently investigated, currently, Pleurotus ostreatus laccase structural model is unknown.

Energy & fatigue

High relevance

Chaga · 2023 · Research Article · Molecules (Basel, Switzerland)

Comparison of Bioactive Secondary Metabolites and Cytotoxicity of Extracts from Inonotus obliquus Isolates from Different Host Species.

Inonotus obliquus, a wood-decaying mushroom, has been used as a health-promoting supplement and nutraceutical for centuries. It is a source of bioactive compounds accumulated in both the conks (pseudosclerotia/sclerotia) and the biomass obtained in vitro..

OncologyLiver supportSkin & hydration

High relevance

Shiitake · 2023 · Research Article · Food science & nutrition

Composition and contents of fatty acids and amino acids in the mycelia of Lentinula edodes.

With the global shortages of animal protein foods, mycoprotein as a low-cost alternative source of protein by its high-protein and low-fat content has become a development trend. Lentinula edodes (L.

High relevance

Cordyceps · 2023 · Journal Article · International microbiology: the official journal of the Spanish Society for Microbiology

Compositional and functional diversities of core microbial communities in wild and artificial Ophiocordyceps sinensis.

Ophiocordyceps sinensis is an entomogenous fungus, and its wildlife resource is very insufficient, as it is widely traded as a natural health product. The artificial culture of O.

Metabolic health

High relevance

Wood Ear · 2023 · Journal Article · Heliyon

Compounds originating from the edible mushroom Auricularia auricula-judae inhibit tropomyosin receptor kinase B activity

Tropomyosin receptor kinase B (TrkB) serves as a pivotal factor in various cancers. To identify novel natural compounds with TrkB-inhibiting properties, a screening approach was applied using extracts from a collection of wild and cultivated mushroom fruiting bodies, and Ba/F3 cells that ectopically express TrkB….

OncologyImmune support

High relevance

Wood Ear · 2023 · Research Article · Heliyon

Compounds originating from the edible mushroom Auricularia auricula-judae inhibit tropomyosin receptor kinase B activity.

OncologyImmune support

High relevance

Reishi · 2023 · Journal Article · Natural product research

Cytotoxic lanostane-type triterpenes from the fruiting bodies of Ganoderma lucidum.

A new lanostane-type triterpene, namely 3-oxo-5α-lanosta-7,9(11)-dien-24-oic acid methyl ester (2), and three known compounds including ganoderal A (1), ganoderiol B (3) and ganodermenonol (4) were isolated from the fruiting bodies of Ganoderma lucidum by silica gel column chromatography and Sephadex LH-20 column….

Oncology

High relevance

Reishi · 2023 · Journal Article · Biomedical chromatography: BMC

Deciphering the chemical composition of Ganoderma lucidum from different geographical origins by mass spectrometry molecular networking coupled with multivariate analysis.

Ganoderma lucidum is a medicinal fungus that has been widely used in China and many Asian countries for thousands of years. This once rare macrofungus has now been artificially cultivated in a number of regions in China..

High relevance

Shiitake · 2023 · Research Article · Mycobiology

Determination and Analysis of Hyper-Variable A Mating Types in Wild Strains of Lentinula edodes in Korea.

The diversity of A mating type in wild strains of Lentinula edodes was extensively analyzed to characterize and utilize them for developing new cultivars. One hundred twenty-three A mating type alleles, including 67 newly discovered alleles, were identified from 106 wild strains collected for the past four decades in….

High relevance

Yellow Morel · 2023 · Journal Article · Journal of the science of food and agriculture

Digestion profile, antioxidant, and antidiabetic capacity of Morchella esculenta exopolysaccharide: in vitro, in vivo and microbiota analysis

BACKGROUND: Novel functional polysaccharides from fungi are important nutraceuticals. An exopolysaccharide, Morchella esculenta exopolysaccharide (MEP 2), was extracted and purified from the fermentation liquor of M.

Immune supportMetabolic healthGut & microbiome

High relevance

Yellow Morel · 2023 · Journal Article · Journal of the science of food and agriculture

Digestion profile, antioxidant, and antidiabetic capacity of Morchella esculenta exopolysaccharide: in vitro, in vivo and microbiota analysis.

Immune supportMetabolic healthGut & microbiome

High relevance

Oyster Mushroom · 2023 · Journal Article · Journal of agricultural and food chemistry

Discovery of Novel Terpenoids from the Basidiomycete Pleurotus ostreatus through Genome Mining and Coculture Optimization.

In our previous work, postredienes A-C, three unusual linear sesterterpenes with high antifungal activities, were isolated from Pleurotus ostreatus SY10 when cocultured with Trametes robiniophila SY636. However, their titers were low, and exploration of newly biosynthesized trace analogues is required..

High relevance

Shiitake · 2023 · Research Article · Foods (Basel, Switzerland)

Disentangling the Tissue-Specific Variations of Volatile Flavor Profiles of the Lentinula edodes Fruiting Body.

For Lentinula edodes, its characteristic flavor is the key determinant for consumer preferences. However, the tissue-specific volatile flavor variations of the fruiting body have been overlooked..

Cognition & nervesSkin & hydration

High relevance

Shiitake · 2023 · Research Article · Frontiers in microbiology

Diversity of Trichoderma species associated with green mold contaminating substrates of Lentinula edodes and their interaction.

INTRODUCTION: The contamination of Trichoderma species causing green mold in substrates poses a significant obstacle to the global production of Lentinula edodes, adversely impacting both yield and quality of fruiting bodies. However, the diversity of Trichoderma species in the contaminated substrates of L..

High relevance

Shiitake · 2023 · Journal Article · Anticancer research

Down-regulating Effect of a Standardized Extract of Cultured Lentinula edodes mycelia on Cortactin in Prostate Cancer Cells Is Dependent on Malignant Potential.

BACKGROUND/AIM: The incidence and mortality rates of prostate cancer have been increasing worldwide. Although prostate cancer cells grow slowly in the local original site, once the cancer cells spread to distant organs they grow rapidly and show very aggressive features..

Oncology

High relevance

Niu-Chang-Chih · 2023 · Research Article · Nutrients

Drastic Synergy of Lovastatin and Antrodia camphorata Extract Combination against PC3 Androgen-Refractory Prostate Cancer Cells, Accompanied by AXL and Stemness Molecules Inhibition.

Prostate cancer (PC) is the second most frequently diagnosed cancer and the fifth leading cause of cancer-related death in males worldwide. Early-stage PC patients can benefit from surgical, radiation, and hormonal therapies; however, once the tumor transitions to an androgen-refractory state, the efficacy of….

Oncology

High relevance

Snow Fungus · 2023 · Journal Article · International journal of food science & technology

Eco‐friendly and non‐toxic lysozyme immobilised on chitosan bacteriostatic agent for strawberry and fresh Tremella fuciformis preservation

Safe and suitable food preservatives can ensure food safety and reduce resource wastage. This paper focuses on the modification of chitosan (CS) using 2,2,6,6‐tetramethylpiperidine‐1‐oxyl radical (TEMPO)/laccase oxidation system and chitosanase..

High relevance

Reishi · 2023 · Journal Article · Food & function

Edible and medicinal mushrooms (Pleurotus ostreatus, Ustilago maydis, Ganoderma lucidum) reduce endoplasmic reticulum stress and inflammation in adipose tissue of obese Wistar rats fed with a high fat plus saccharose diet.

Obesity is an increasing global public health problem. A strategy to treat obesity is the use of functional foods.

Immune supportMetabolic healthGut & microbiomeSkin & hydration

High relevance

Enoki · 2023 · Journal Article · Journal of food science

Effect of Flammulina velutipes polysaccharides on endoplasmic reticulum stress-mediated apoptosis by activating PLC-IP3 pathway in HepG2 cells.

Flammulina velutipes polysaccharides (FVP) have been proven to induce apoptosis in HepG2 cells. It is well known that endoplasmic reticulum stress (ERS) is involved in apoptosis.

OncologyImmune supportMetabolic health

High relevance

Enoki · 2023 · Research Article · Frontiers in nutrition

Effect of Flammulina velutipes polysaccharides on the physicochemical properties of catfish surimi and myofibrillar protein oxidation during frozen storage.

This study investigated the effect of Flammulina velutipes polysaccharides (FVPs) on the myofibrillar protein (MP) oxidation protein and physicochemical properties of catfish surimi during 75 days of frozen storage at -18°C..

Immune support