MycoData

Morchella esculenta polysaccharides exhibit numerous probiotic activities, but their regulatory effects on the gut microbiota are unclear. This study was conducted to explore whether M.

Immune supportMetabolic healthGut & microbiomeLiver support

High relevance

Reishi · 2023 · Research Article · ACS omega

Effects of a Ganoderma lucidum Proteoglycan on Type 2 Diabetic Rats and the Recovery of Rat Pancreatic Islets.

Type 2 diabetes (T2D) results from both insulin resistance and pancreatic β-cell dysfunction. A natural proteoglycan extracted from Ganoderma lucidum, namely, FYGL, has been demonstrated to be capable of ameliorating insulin resistance in previous work..

Metabolic health

High relevance

Shiitake · 2023 · Journal Article · Food chemistry

Effects of continuous enzymolysis on the umami characteristics of Lentinula edodes and the flavor formation mechanism of umami peptides.

The purpose of this study was to explore the effect of continuous enzymolysis on the umami characteristics of Lentinula edodes and illuminate the umami mechanism of peptides..

High relevance

Snow Fungus · 2023 · Research Article · Foods (Basel, Switzerland)

Effects of Different Blanching Methods on the Quality of Tremella fuciformis and Its Moisture Migration Characteristics.

Blanching is a critical step in the processing of Tremella fuciformis (T. fuciformis).

Immune support

High relevance

Reishi · 2023 · Journal Article · Food Research International

Effects of drying methods on bioactive components of Ganoderma lucidum fermented whole wheat in products &in vitro digestive model

The content of bioactive components is the key to determining the quality of Ganoderma lucidum fermented whole wheat (GW) products, and drying is a necessary link in the initial processing of GW, which will affect the bioactivity and quality of GW..

Immune supportEnergy & fatigueGut & microbiome

High relevance

Enoki · 2023 · Research Article · Food science and biotechnology

Effects of Flammulina velutipes polysaccharides on gut microbiota composition and metabolism in vitro fermentation.

UNLABELLED: Flammulina velutipes polysaccharides (FVP) exhibit many biological activities, but the effects on gut microflora and metabolism were still unclear. Here, we explored the composition of FVP, their influence on human gut microflora composition and metabolites..

Immune supportMetabolic healthGut & microbiome

High relevance

Lion's Mane · 2023 · Journal Article · Journal of basic microbiology

Effects of Hericium erinaceus Hedgehog mushroom on the endophytic microbial community of the host plant.

Hedgehog mushroom is a Hericium erinaceus associated with fagaceae and pinaceae trees in the northern hemisphere. It is still unknown whether this symbiotic relationship will affect the endophytic microbial community of the host plants..

High relevance

Reishi · 2023 · Journal Article · PloS one

Effects of Mexican Ganoderma lucidum extracts on liver, kidney, and the gut microbiota of Wistar rats: A repeated dose oral toxicity study.

Well-characterized and standardized extracts of a Mexican genotype of Ganoderma lucidum (Gl), a medicinal mushroom, cultivated on oak sawdust (Gl-1) or oak sawdust plus acetylsalicylic acid (Gl-2, ASA), have been shown to exert antioxidant, hypocholesterolemic, anti-inflammatory, prebiotic, and anticancer properties..

OncologyImmune supportMetabolic healthGut & microbiome

High relevance

Wood Ear · 2023 · Journal Article · Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire

Effects of protein-polysaccharide extracted from Auricularia auricula-judae mushroom on the quality characteristics of Chinese wheat noodles

This study revealed the effect of protein-polysaccharide extracted from Auricularia auricula-judae fruiting bodies (AAP) on the textural properties and microstructures of Chinese wheat noodles. In addition, the underlying mechanisms were explored..

Immune support

High relevance

Oyster Mushroom · 2023 · Research Article · Animals: an open access journal from MDPI

Effects of the Incubation Period of Pleurotus ostreatus on the Chemical Composition and Nutrient Availability of Solid-State-Fermented Corn Stover.

The current study aimed to optimize and improve the feeding value of Pleurotus ostreatus-fermented corn stover by evaluating the effects of five solid-state fermentation times and three in vitro fermentation periods on the chemical composition, dry matter disappearance (DMD), microbial mass and volatile fatty acid….

Gut & microbiome

High relevance

Snow Fungus · 2023 · Research Article · Ultrasonics sonochemistry

Effects of ultrasonic-enzymatic-assisted ethanol precipitation method on the physicochemical characteristics, antioxidant and hypoglycemic activities of Tremella fuciformis polysaccharides.

This investigation involved the extraction of a novel polysaccharide from the spore fermentation broth of Tremella fuciformis using a method that combined ultrasonic and enzymatic assistance with ethanol precipitation. It was then compared with enzymatic and ultrasonic extraction methods..

Immune supportEnergy & fatigueMetabolic health

High relevance

Enoki · 2023 · Research Article · Antioxidants (Basel, Switzerland)

Effects of UV Stress in Promoting Antioxidant Activities in Fungal Species Тrametes versicolor (L.) Lloyd and Flammulina velutipes (Curtis) Singer.

Trametes versicolor and Flammulina velutipes, after submerged cultivation, with intermittent exposure to ultraviolet light (UV), were studied for Total Phenolic content (TP) and Total Proteins (TPR) contents and antioxidant properties against free radicals..

Skin & hydration

High relevance

Oyster Mushroom · 2023 · Journal Article · Chemosphere

Efficient decolorization and detoxification of triarylmethane and azo dyes by porous-cross-linked enzyme aggregates of Pleurotus ostreatus laccase.

In this preset study, porous-cross-linked enzyme aggregates (CLEAs) of Pleurotus ostreatus laccase were utilized for the spontaneous decolorization and detoxification of triarylmethane and azo dyes, reactive blue 2 (RB) and malachite green (MG)..

Energy & fatigue

High relevance

Turkey Tail · 2023 · Research Article · Brazilian journal of microbiology: [publication of the Brazilian Society for Microbiology]

Enhanced laccase activity in Trametes versicolor (L.: Fr.) Pilát by host substrate and copper.

Laccases are appealing biocatalysts for various industrial utilizations. The fungus Trametes versicolor (L.: Fr.) Pilát causes white rot in wood and has been identified as an important fungal laccase producer.

High relevance

Mesima · 2023 · Journal Article · International journal of medicinal mushrooms

Enhanced Yield of Bioactive Compounds and Antioxidant Activities in Four Fermented Beans of Phellinus linteus Strains (Agaricomycetes) by Solid-State Fermentation.

Phellinus linteus is a famous medicinal mushroom which exhibits various biological activities. This study aimed to investigate the effects of solid-state fermentation by Ph.

Immune support

High relevance

Lion's Mane · 2023 · Research Article · Molecules (Basel, Switzerland)

Enrichment Extraction and Activity Study of the Different Varieties of Hericium erinaceus against HCT-8 Colon Cancer Cells.

Hericium erinaceus (HE), a widely utilized natural remedy and dietary source, has garnered significant attention for its therapeutic potential in various diseases. In this study, we employed supercritical fluid extraction (SFE) technology to isolate the bioactive compounds from HE's fruiting body..

OncologyGut & microbiome

High relevance

Lion's Mane · 2023 · Journal Article · Journal of agricultural and food chemistry

Evaluation of the "Relative Ordered Structure of Hericium erinaceus Polysaccharide" from Different Origins: Based on Similarity and Dissimilarity.

Polysaccharides are organic compounds widely distributed in nature, but structural order and disorder remain a formidable problem. In this study, based on the theoretical framework of the "relative ordered structure of polysaccharide" proposed in our previous work, the structural order of Hericium erinaceus….

Immune support

High relevance

Oyster Mushroom · 2023 · Research Article · Open life sciences

Exopolysaccharides from Pseudomonas tolaasii inhibit the growth of Pleurotus ostreatus mycelia.

In the present study, the effect of exopolysaccharides (EPSs) extracted from Pseudomonas tolaasii on the growth of Pleurotus ostreatus mycelia was determined. P.

Immune supportMetabolic health

High relevance

Zhu Ling · 2023 · Journal Article · International journal of biological macromolecules

Extraction, characterization, and anti-nonalcoholic steatohepatitis activity of a (1,3) (1,6)-β-D-glucan from the Polyporus umbellatus (Pers.) Fries.

Nonalcoholic steatohepatitis (NASH) is a chronic liver disease characterized by inflammation and hepatic steatosis that may coincide with fibrotic activity. To date, no pharmacological agents have been approved for NASH treatment..

Immune supportLiver support

High relevance

Enoki · 2023 · Journal Article · Food chemistry

Flammulina velutipes polysaccharide improves the water-holding capacity in the dorsal muscle of freeze-thawed cultured large yellow croaker (Larimichthys crocea).

To investigate the effect of Flammulina velutipes polysaccharide (FVP) on the water-holding capacity (WHC) in the dorsal muscle of freeze-thawed large yellow croaker, fresh fish were treated with FVP, commercial cryoprotectant (CC), and distilled water before freezing..

Immune supportEnergy & fatigueSkin & hydration

High relevance

Enoki · 2023 · Journal Article · International journal of biological macromolecules

Flammulina velutipes polysaccharides regulate lipid metabolism disorders in HFD-fed mice via bile acids metabolism.

Our recent study demonstrated that the dynamic changes of gut microbiota mediated by Flammulina velutipes polysaccharide (FVP) could effectively regulate the lipid metabolism in high fat diet-fed (HFD-fed) obese mice model..

Immune supportMetabolic healthGut & microbiomeLiver support

High relevance

Enoki · 2023 · Research Article · Poultry science

Flammulina velutipes stem regulates oxidative damage and synthesis of yolk precursors in aging laying hens by regulating the liver-blood-ovary axis.

Egg production levels in late laying hens are negatively correlated with increasing age. Decreased liver and ovarian function in aging laying hens is accompanied by decreased antioxidant capacity, reproductive hormone levels, and follicular development, resulting in decreased synthesis of yolk precursors..

OncologyImmune supportEnergy & fatigueMetabolic health

High relevance

Enoki · 2023 · Journal Article · Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy

Flammulina velutipes-derived carbon dots for fluorescence detection and imaging of hydroxyl radical.

Monitoring hydroxyl radical (•OH) fluctuation is of great importance to study some relative pathological processes and to predict early diagnosis of diseases. Efficient •OH-responsive fluorescent sensors based on carbon dots (CDs) have been reported, but most researches have focused on the new strategies for the….

High relevance

Agarikon · 2023 · Research Article · Antibiotics (Basel, Switzerland)

Fomitopsis officinalis: Spatial (Pileus and Hymenophore) Metabolomic Variations Affect Functional Components and Biological Activities.

Fomitopsis officinalis is a holartic polyporous mushroom that forms large fruiting bodies on old standing trees, fallen logs, or stumps. F.

Metabolic health

High relevance

Reishi · 2023 · Journal Article · FEMS microbiology letters

Function of a hydrophobin in growth and development, nitrogen regulation, and abiotic stress resistance of Ganoderma lucidum.

Fungal hydrophobins have many important physiological functions, such as maintaining hydrophobicity and affecting virulence, growth, and development. In Ganoderma lucidum, the molecular regulation mechanisms of hydrophobins in mushroom are unclear.

High relevance

Oyster Mushroom · 2023 · Research Article · International journal of molecular sciences

Function of Transcription Factors PoMYB12, PoMYB15, and PoMYB20 in Heat Stress and Growth of Pleurotus ostreatus.

MYB transcription factors (TFs) have been extensively studied in plant abiotic stress responses and growth and development. However, the role of MYB TFs in the heat stress response and growth and development of Pleurotus ostreatus remains unclear.

High relevance

Enoki · 2023 · Research Article · Journal of fungi (Basel, Switzerland)

FvbHLH1 Regulates the Accumulation of Phenolic Compounds in the Yellow Cap of Flammulina velutipes.

Flammulina velutipes is a renowned edible and medicinal fungus. Commercially cultivated F.

Skin & hydration

High relevance

Reishi · 2023 · Case Reports · Cureus

Ganoderma lingzhi (Reishi Mushroom)-Induced Acute Liver Injury in the Setting of Alcohol Use: A Case Report and Review of the Literature.

As many prior case reports have shown, unregulated supplements and alcohol are both known to cause varying degrees of hepatotoxicity. We present a case of a 47-year-old male who presented to the hospital with headache and abdominal pain after consuming Reishi Mushroom (Ganoderma lingzhi) powder and alcohol..

Liver support

High relevance

Reishi · 2023 · Research Article · RSC advances

Ganoderma lucidum bran-derived blue-emissive and green-emissive carbon dots for detection of copper ions.

Ganoderma lucidum bran (GB) has a broad application prospect in the preparation of activated carbon, livestock feed, and biogas, but the preparation of carbon dots (CDs) from GB has never been reported..

High relevance

Reishi · 2023 · Journal Article · Food and chemical toxicology: an international journal published for the British Industrial Biological Research Association

Ganoderma lucidum extract promotes tumor cell pyroptosis and inhibits metastasis in breast cancer.

Regulation of tumor cell death is a fundamental mechanism for tumor treatment. However, most tumors are resistant to cell death.

OncologyImmune supportEnergy & fatigueGut & microbiome

High relevance

Reishi · 2023 · Research Article · Scientific reports

Ganoderma lucidum methanolic extract as a potent phytoconstituent: characterization, in-vitro antimicrobial and cytotoxic activity.

Ganoderma lucidum methanolic extract (GLME) has attracted tremendous attention due to its exceptional antimicrobial and anticancer properties that can be delicately tuned by controlling the initial extraction's content and concentration..

OncologyEnergy & fatigue

High relevance

Reishi · 2023 · Research Article · Molecules (Basel, Switzerland)

Ganoderma lucidum Mycelia Mass and Bioactive Compounds Production through Grape Pomace and Cheese Whey Valorization.

Numerous compounds obtained from the medicinal mushroom Ganoderma lucidum have evidenced renowned bioactive characteristics. Controlled fermentation to generate fungal mycelia confers several advantages, specifically when the valorization of agro-industrial streams as fermentation feedstocks is included..

Immune support

High relevance

Reishi · 2023 · Journal Article · Phytomedicine: international journal of phytotherapy and phytopharmacology

Ganoderma lucidum polysaccharide inhibits HSC activation and liver fibrosis via targeting inflammation, apoptosis, cell cycle, and ECM-receptor interaction mediated by TGF-β/Smad signaling.

BACKGROUND: Ganoderma lucidum polysaccharide (GLP) has many biological properties, however, the anti-fibrosis effect of GLP is unknown at present. PURPOSE: This study aimed to examine the anti-fibrogenic effect of GLP and its underlying molecular mechanisms in vivo and in vitro..

OncologyImmune supportLiver supportSkin & hydration

High relevance

Reishi · 2023 · Journal Article · Phytomedicine: international journal of phytotherapy and phytopharmacology

Ganoderma lucidum polysaccharide peptide (GLPP) attenuates rheumatic arthritis in rats through inactivating NF-κB and MAPK signaling pathways.

BACKGROUND: Not many drugs with fewer side effects are available for the treatment of rheumatoid arthritis (RA). Ganoderma lucidum polysaccharide peptide (GLPP) has good immunomodulatory effects, but whether it is effective in managing RA is not clear..

OncologyImmune supportLiver supportSkin & hydration

High relevance

Reishi · 2023 · Journal Article · International journal of biological macromolecules

Ganoderma lucidum polysaccharide peptides GL-PPSQ2 alleviate intestinal ischemia-reperfusion injury via inhibiting cytotoxic neutrophil extracellular traps.

Ganoderma lucidum polysaccharides peptides (GLPP) are the main effective ingredients from G. lucidum (Leyss.

OncologyImmune supportMetabolic healthGut & microbiome

High relevance

Reishi · 2023 · Journal Article · Journal of ethnopharmacology

Ganoderma lucidum polysaccharides improve lipid metabolism against high-fat diet-induced dyslipidemia.

ETHNOPHARMACOLOGICAL RELEVANCE: As a kind of traditional medicinal fungi, Ganoderma lucidum has been employed as folk medicine in China against multiple metabolic diseases on account of its superior bioactivities. Recently, accumulated reports have investigated the protective effects of G..

Immune supportMetabolic healthGut & microbiome

High relevance

Maitake · 2023 · Journal Article · International journal of biological macromolecules

Gastrointestinal metabolism characteristics and mechanism of a polysaccharide from Grifola frondosa.

Grifola frondosa polysaccharide (GFP) is mainly composed of α-1,4 glycosidic bonds and possesses multiple pharmacological activities. However, the absence of pharmacokinetic studies has limited its further development and utilization..

Immune supportGut & microbiomeLiver support

High relevance

Zhu Ling · 2023 · Journal Article · Journal of agricultural and food chemistry

Generation of Meaty Aroma from Onion (Allium cepa L.) with Polyporus umbellatus: Fermentation System, Sensory Profile, and Aroma Characterization.

One of the main reasons for consumer rejection of plant-based meat alternatives is the lack of meaty flavor after cooking. In this study, a platform was developed to generate meaty flavors solely from Allium substrates (chives, leeks, ramsons, and onions) using basidiomycete-mediated submerged fermentations..

Liver support

High relevance

Oyster Mushroom · 2023 · Journal Article · Food Research International

Heat stress and excessive maturity of fruiting bodies suppress GABA accumulation by modulating GABA metabolism in Pleurotus ostreatus (Jacq. ex Fr.) P. Kumm

GABA is a health-promoting bioactive substance. Here, the GABA biosynthetic pathways were investigated, and then the dynamic quantitative changes in GABA and the expression levels of genes related to GABA metabolism under heat stress or at different developmental stages of fruiting bodies in Pleurotus ostreatus (Jacq..

High relevance

Lion's Mane · 2023 · Research Article · Biology

Hericium erinaceus Extract Exerts Beneficial Effects on Gut-Neuroinflammaging-Cognitive Axis in Elderly Mice.

Ageing is a biological phenomenon that determines the impairment of cognitive performances, in particular, affecting memory. Inflammation and cellular senescence are known to be involved in the pathogenesis of cognitive decline..

Immune supportCognition & nervesEnergy & fatigueGut & microbiome

High relevance

Lion's Mane · 2023 · Journal Article · Bioscience, biotechnology, and biochemistry

Hericium erinaceus polysaccharide improves the microstructure, immune function, proliferation and reduces apoptosis of thymus and spleen tissue cells of immunosuppressed mice.

In order to study the effect of Hericium erinaceus polysaccharide (HEP) on the immune and antioxidation functions of immunosuppressed mice. The control group received distilled water orally and the model and experimental groups I, II, and III received 0, 80, 160, and 320 mg/kg HEP respectively for a fortnight after….

OncologyImmune support

High relevance

Lion's Mane · 2023 · Research Article · International journal of molecular sciences

Hericium erinaceus Promotes Anti-Inflammatory Effects and Regulation of Metabolites in an Animal Model of Cerebellar Ataxia.

Cerebellar ataxia is a neurodegenerative disorder with no definitive treatment. Although previous study demonstrated the neuroprotective effects of Hericium erinaceus (H.E.), the mechanisms of H.E.

Immune supportCognition & nervesEnergy & fatigueMetabolic health

High relevance

Lion's Mane · 2023 · Research Article · Frontiers in immunology

Hericium erinaceus, in combination with natural flavonoid/alkaloid and B3/B8 vitamins, can improve inflammatory burden in Inflammatory bowel diseases tissue: an ex vivo study.

Hericium erinaceus, berberine, and quercetin are effective in experimental colitis. It is unknown whether they can ameliorate inflammatory bowel diseases in humans.

Immune supportGut & microbiome

High relevance

Enoki · 2023 · Research Article · Journal of fungi (Basel, Switzerland)

Heterogeneous Distribution of Phospholipid Molecular Species in the Surface Culture of Flammulina velutipes: New Facts about Lipids Containing α-Linolenic Fatty Acid.

Mycelial fungi grow as colonies consisting of polar growing hyphae, developing radially from spore or inoculum. Over time, the colony develops, hyphae are subject to various exogenous or endogenous stimuli, and mycelium becomes heterogeneous in growth, gene expression, biosynthesis, and secretion of proteins and….

Metabolic healthGut & microbiome

High relevance

Shiitake · 2023 · Research Article · Journal of fungi (Basel, Switzerland)

HOG1 Mitogen-Activated Protein Kinase Pathway-Related Autophagy Induced by H2O2 in Lentinula edodes Mycelia.

Mycelial ageing is associated with ROS and autophagy in Lentinula edodes. However, the underlying cellular and molecular mechanisms between ROS and autophagy remain obscure.

High relevance

Shiitake · 2023 · Research Article · Frontiers in microbiology

Hydrated lime promoted the polysaccharide content and affected the transcriptomes of Lentinula edodes during brown film formation.

Brown film formation, a unique developmental stage in the life cycle of Lentinula edodes, is essential for the subsequent development of fruiting bodies in L. edodes cultivation.

Immune supportMetabolic health

High relevance

Maitake · 2023 · Research Article · Journal of fungi (Basel, Switzerland)

Identification and Characterization of a Predominant Hydrophobin in the Edible Mushroom Grifola frondosa.

Hydrophobins (HFBs) are a group of small, secreted amphipathic proteins of fungi with multiple physiological functions and potential commercial applications. In this study, HFB genes of the edible mushroom, Grifola frondosa, were systematically identified and characterized, and their transcriptional profiles during….

High relevance

Mesima · 2023 · Journal Article · International journal of biological macromolecules

Identification of galacturonic acid-rich polysaccharide with intestinal immune system modulating activity via Peyer's patch from postbiotics of Phellinus linteus mycelial submerged culture.

Interests in the development and exploration of industrial applications of medicinal mushrooms as postbiotics have lately increased. We recently reported the potential use of Phellinus linteus mycelial-containing whole culture extract (PLME) prepared by submerged cultivation as a postbiotic that promotes immune system….

Immune supportGut & microbiome

High relevance

Oyster Mushroom · 2023 · Research Article · Journal of pesticide science

Identification of two phthalide derivatives and an oxindole compound isolated from the edible mushroom Pleurotus ostreatus and their inhibitory activities against plant pathogenic microorganisms.

The excessive use of chemical pesticides in agricultural fields for controlling plant pathogenic microorganisms harms human health, the environment, and other beneficial microorganisms in the soil and plants..

High relevance

Reishi · 2023 · Journal Article · Journal of fish diseases

Immune-enhancing effects of Astragalus polysaccharides and Ganoderma lucidum polysaccharides on Vibrio harveyi flgJ DNA vaccine in grouper.

Astragalus polysaccharides (APS) and Ganoderma lucidum polysaccharides (GLP) have been shown to possess strong immunoregulatory properties in aquatic animals. In this study, the fragment containing Vibrio harveyi flgJ gene was ligated into pcDNA3.1(+) vector and pcDNA3.1(+)-flgJ was constructed as DNA vaccine..

Immune supportLiver support