MycoData

OncologyImmune supportEnergy & fatigue

Cordyceps · 2023 · Journal Article · International immunopharmacology

Cordycepin suppresses vascular inflammation, apoptosis and oxidative stress of arterial smooth muscle cell in thoracic aortic aneurysm with VEGF inhibition.

BACKGROUND: Thoracic aortic aneurysm (TAA) is a type of common and serious vascular disease, in which inflammation, apoptosis and oxidative stress are strongly involved in the progression. Cordycepin, a bioactive compound from Cordyceps militaris, exhibits anti-inflammatory and anti-oxidative activities..

Cordyceps · 2023 · Journal Article · International journal of biological macromolecules

Horizontal gene transfer of Cccyt contributes to virulence of mycoparasite Calcarisporium cordycipiticola by interacting with a host heat shock protein.

Horizontal gene transfer (HGT) is an important driving force for virulence evolution of pathogens, however, functions of these transferred genes are still not fully investigated..

OncologyImmune supportRespiratory

Cordyceps · 2023 · Journal Article · Microorganisms

Natural Product Cordycepin (CD) Inhibition for NRP1/CD304 Expression and Possibly SARS-CoV-2 Susceptibility Prevention on Cancers.

NRP1/CD304 is a typical membrane-bound co-receptor for the vascular endothelial cell growth factor (VEGF), semaphorin family members, and viral SARS-CoV-2. Cordycepin (CD) is a natural product or active gradient from traditional Chinese medicine (TCM) from Cordyceps militaris Link and Ophiocordyceps sinensis (Berk.)..

Chaga · 2023 · Research Article · Heliyon

Preventive effects of inotodiol on polyinosinic-polycytidylic acid-induced inflammation in human dermal fibroblasts.

Double-strand RNA(dsRNA), which can induce inflammation, can be generated by necrotic keratinocytes in the skin environment. As an analog of dsRNA, polyinosinic-polycytidylic acid (poly(I:C)) is used to induce inflammation via the Toll-like Receptor 3 (TLR3) signaling pathway..

Chaga · 2023 · Journal Article · Heliyon

Preventive effects of inotodiol on polyinosinic–polycytidylic acid-induced inflammation in human dermal fibroblasts

Double-strand RNA(dsRNA), which can induce inflammation, can be generated by necrotic keratinocytes in the skin environment. As an analog of dsRNA, polyinosinic–polycytidylic acid (poly(I:C)) is used to induce inflammation via the Toll-like Receptor 3 (TLR3) signaling pathway..

OncologyImmune supportGut & microbiome

Cordyceps · 2022 · Journal Article · International immunopharmacology

Cordycepin enhances anti-tumor immunity in colon cancer by inhibiting phagocytosis immune checkpoint CD47 expression.

Cordycepin, also known as 3'-deoxyadenosine, is an extract from Cordyceps militaris, which has been reported as an anti-inflammation and anti-tumor substance without toxicity. However, the pharmacological mechanism of Cordycepin on tumor immunity under its anti-tumor effect has not yet been elucidated..

Cordyceps · 2022 · Research Article · Pharmaceutical biology

Cordycepin mitigates spermatogenic and redox related expression in H2O2-exposed Leydig cells and regulates testicular oxidative apoptotic signalling in aged rats.

CONTEXT: Cordycepin (COR), from Cordyceps militaris L., (Cordycipitaceae), is a valuable agent with immense health benefits. OBJECTIVE: The protective effects of COR in ageing-associated oxidative and apoptosis events in vivo and hydrogen peroxide (H2O2)-exposed spermatogenesis gene alterations in TM3 Leydig cells was….

Cordyceps · 2022 · Journal Article · Journal of food biochemistry

Cordycerebroside A inhibits ICAM‐1‐dependent M1 monocyte adhesion to osteoarthritis synovial fibroblasts

Osteoarthritis (OA) is represented by the accumulation and adhesion of M1 macrophages into synovium tissues in the joint microenvironment and subsequent inflammatory response..

OncologyImmune supportGut & microbiome

Shiitake · 2022 · Journal Article · Journal of food composition and analysis

Facile extraction of nanosized β-glucans from edible mushrooms and their antitumor activities

It has been recently reported that, β-Glucans with globular small particle size confer a higher disease resistance due to its induced strong immunomodulating activity. Herein, this work was designed to directly extract the nano β-glucans (NGs) from mushrooms using an acid-base procedure..

Reishi · 2022 · Journal Article · Journal of ethnopharmacology

Integrating network pharmacology and experimental models to investigate the efficacy of QYHJ on pancreatic cancer.

ETHNOPHARMACOLOGICAL RELEVANCE: The Qingyihuaji decoction (QYHJ) is composed of seven herbs: Scutellaria barbata D.Don (Banzhilian, HSB), Gynostemma pentaphyllum (Thunb.) Makino (Jiaogulan, GP), Oldenlandia diffusa (Willd.) Roxb. (Baihuasheshecao, HDH), Ganoderma lucidum (Leyss.

Cordyceps · 2021 · Research Article · Evidence-based complementary and alternative medicine: eCAM

A Network Pharmacology Study on the Molecular Mechanisms of FDY003 for Breast Cancer Treatment.

Herbal medicines have drawn considerable attention with regard to their potential applications in breast cancer (BC) treatment, a frequently diagnosed malignant disease, considering their anticancer efficacy with relatively less adverse effects..

Immune supportMetabolic healthLiver support

Cordyceps · 2021 · Journal Article · International immunopharmacology

Cordycepin attenuates high-fat diet-induced non-alcoholic fatty liver disease via down-regulation of lipid metabolism and inflammatory responses.

Cordycepin (CRD), an adenosine analog derived from traditional Chinese medicine, is an active component in Cordyceps militaris. It has been shown to have many protective effects during liver injury and ameliorate liver disease progression, but little is known about its effect on non-alcoholic fatty liver disease….

Immune supportCognition & nerves

Cordyceps · 2021 · Journal Article · Journal of neuroinflammation

Cordycepin confers long-term neuroprotection via inhibiting neutrophil infiltration and neuroinflammation after traumatic brain injury.

BACKGROUND: The secondary injury caused by traumatic brain injury (TBI), especially white matter injury (WMI), is highly sensitive to neuroinflammation, which further leads to unfavored long-term outcomes..

OncologyImmune supportCognition & nervesSkin & hydration

Cordyceps · 2021 · Journal Article · American journal of cancer research

Cordycepin inhibits the proliferation of malignant peripheral nerve sheath tumor cells through the p53/Sp1/tubulin pathway.

Neurofibromatosis type 1 (NF1) is one of the most common hereditary neurocutaneous disorders. In addition to skin pigmentation and cutaneous neurofibroma, some patients developed the plexiform neurofibroma since birth..

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

King Oyster · 2021 · Research Article · Animal bioscience

Effects of mushroom waster medium and stalk residues on the growth performance and oxidative status in broilers.

OBJECTIVE: The study developed mushroom stalk residues as feed additives in the broiler diet for improving the growth performance and immunity of broilers as well as to increase the value of mushroom stalk residues..

Cordyceps · 2021 · Research Article · International journal of molecular sciences

Ergosta-7, 9 (11), 22-trien-3β-ol Interferes with LPS Docking to LBP, CD14, and TLR4/MD-2 Co-Receptors to Attenuate the NF-κB Inflammatory Pathway In Vitro and Drosophila.

Ergosta-7, 9 (11), 22-trien-3β-ol (EK100) was isolated from Cordyceps militaris, which has been used as a traditional anti-inflammatory medicine. EK100 has been reported to attenuate inflammatory diseases, but its anti-inflammatory mechanism is still unclear..

OncologyImmune supportEnergy & fatigue

Cordyceps · 2021 · Research Article · Antioxidants (Basel, Switzerland)

Ergosta-7,9(11),22-trien-3β-ol Attenuates Inflammatory Responses via Inhibiting MAPK/AP-1 Induced IL-6/JAK/STAT Pathways and Activating Nrf2/HO-1 Signaling in LPS-Stimulated Macrophage-like Cells.

Chronic inflammation induces autoimmune disorders and chronic diseases. Several natural products activate nuclear factor erythroid 2-related factor 2 (Nrf2) signaling, attenuating inflammatory responses..

Snow Fungus · 2021 · Research Article · Journal of cosmetic dermatology

Formulation and efficacy evaluation of the safe and efficient moisturizing snow mushroom hand sanitizer.

OBJECTIVES: Snow fungus or snow mushroom or white jelly mushroom (Tremella fuciformis), the edible mushroom, was formulated into hand sanitizer in form of moisturizing alcohol-based hand rub (ABHR) gel. METHODS: The stable base ABHRs were developed..

Immune supportGut & microbiomeLiver support

King Oyster · 2021 · Research Article · Animals: an open access journal from MDPI

Intestinal Microbiota, Anti-Inflammatory, and Anti-Oxidative Status of Broiler Chickens Fed Diets Containing Mushroom Waste Compost By-Products.

This study investigated the effects of using mushroom waste compost as the residue medium for Pleurotus eryngii planting, which was used as a feed replacement; its consequent influence on broiler chickens' intestinal microbiota, anti-inflammatory responses, and anti-oxidative status was likewise studied..

Immune supportSkin & hydrationRespiratory

Chaga · 2021 · Journal Article · International journal of medicinal mushrooms

Medicinal Mushrooms against Influenza Viruses.

This review provides results obtained by scientists from different countries on the antiviral activity of medicinal mushrooms against influenza viruses that can cause pandemics..

Cordyceps · 2021 · Research Article · Journal of biomedical research

Ovalicin attenuates atopic dermatitis symptoms by inhibiting IL-31 signaling and intracellular calcium influx.

Atopic dermatitis (AD) is a common skin disorder difficult to be treated with medication. This study investigated the potential of ovalicin extracted from Cordyceps militaris for the treatment of AD using in vitro and in vivo models..

King Oyster · 2021 · Research Article · Nutrients

The Use of Mushrooms and Spirulina Algae as Supplements to Prevent Growth Inhibition in a Pre-Clinical Model for an Unbalanced Diet.

Today's eating patterns are characterized by the consumption of unbalanced diets (UBDs) resulting in a variety of health consequences on the one hand, and the consumption of dietary supplements in order to achieve overall health and wellness on the other..

OncologyImmune supportRespiratory

Shiitake · 2019 · Research Support, Non U.S. Gov'T · Progress in molecular biology and translational science

Mushroom polysaccharide lentinan for treating different types of cancers: A review of 12 years clinical studies in China.

Lentinula edodes has been used to improve general health for thousands of years in Asia. It is the second largest cultivated and the most popular edible mushroom in the world known as "Xianggu" in China and "Shiitake" in Japan.

Reishi · 2005 · Journal Article · Journal of Pharmacological Sciences

Cellular and Molecular Mechanisms of Immuno-modulation by Ganoderma lucidum

Ganoderma lucidum (Leyss. ex Fr.) Karst.

OncologyImmune supportMetabolic healthLiver support

Reishi · 2005 · Journal Article · Mushroom Science and Biotechnology

Development of the method for efficient disruption and rapid extraction on the β-1,3-glucan determination from the mycelium of Ganoderma lucidum

Metadata-grounded summary: This journal article indexes research on Ganoderma lucidum in Mushroom Science and Biotechnology in 2005. MycoData maps the paper to oncology, immune support, metabolic health, liver support based on its title, species context, article metadata, and study classification..

Enoki · 2005 · Journal Article · Journal of Applied Glycoscience

Effect of Culture Medium Components on Cultivation of Flammulina velutipes and Characteristics of Fruit Body

Metadata-grounded summary: This journal article indexes research on Flammulina velutipes in Journal of Applied Glycoscience in 2005. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Almond Mushroom · 2005 · Journal Article · Bioscience, Biotechnology, and Biochemistry

In Vitro Augmentation of Natural Killer Activity and Interferon-γ Production in Murine Spleen Cells with Agaricus blazei Fruiting Body Fractions

Aqueous extracts of the Agaricus blazei fruiting body prepared at different temperatures were fractionated by ethanol precipitation with various ethanol concentrations. The original aqueous extracts of A..

Almond Mushroom · 2005 · Journal Article · Mokuzai Gakkaishi

Influence of Culture Medium Components on the Pharmacological Effects of Agaricus blazei

Metadata-grounded summary: This journal article indexes research on Agaricus blazei in Mokuzai Gakkaishi in 2005. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Shiitake · 2005 · Journal Article · Mushroom Science and Biotechnology

Influence of supplements in sawdust substrates on fruit body tastes of Lentinula edodes

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in Mushroom Science and Biotechnology in 2005. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

Maitake · 2005 · Journal Article · IEEJ Transactions on Sensors and Micromachines

Investigation of the Optimum Farming Temperature for Grifola frondosa and Growth Promotion using the Bio-Electric Potential as an Index

Metadata-grounded summary: This journal article indexes research on Grifola frondosa in IEEJ Transactions on Sensors and Micromachines in 2005. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Enoki · 2005 · Journal Article · Mycoscience

Production of enokipodins A, B, C, and D: a new group of antimicrobial metabolites from mycelial culture of Flammulina velutipes

Metadata-grounded summary: This journal article indexes research on Flammulina velutipes in Mycoscience in 2005. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Almond Mushroom · 2005 · Journal Article · 化学工学会研究発表講演要旨集

気泡塔により液体培養したAgaricus blazei菌糸の代謝成分に及ぼす通気条件の影響

Metadata-grounded summary: This journal article indexes research on Agaricus blazei in 化学工学会研究発表講演要旨集 in 2005. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Yellow Morel · 2004 · Journal Article · Food chemistry

Antioxidant properties of methanolic extracts from Grifola frondosa, Morchella esculenta and Termitomyces albuminosus mycelia.

Metadata-grounded summary: This journal article indexes research on Morchella esculenta in Food chemistry in 2004. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Maitake · 2004 · Journal Article · Shokubutsu Kojo Gakkaishi

Bio-Electric Potential of Grifola frondosa under Light Stimuli. (Part 4)

Metadata-grounded summary: This journal article indexes research on Grifola frondosa in Shokubutsu Kojo Gakkaishi in 2004. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Shiitake · 2004 · Journal Article · Mycoscience

Biological and inherited characteristics of a newly identified Lentinula edodes strain capable of forming a fruiting body without a shift to low temperature

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in Mycoscience in 2004. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

Turkey Tail · 2004 · Journal Article · Asian Pacific Confederation of Chemical Engineering congress program and abstracts

Decolorization of Dye Solutions by a Ceramic Membrane Bioreactor using Trametes Versicolor KCTC 16781

Metadata-grounded summary: This journal article indexes research on Trametes versicolor in Asian Pacific Confederation of Chemical Engineering congress program and abstracts in 2004. MycoData maps the paper to oncology, immune support based on its title, species context, article metadata, and study classification..

OncologyImmune supportMetabolic healthLiver support

Reishi · 2004 · Journal Article · Mushroom Science and Biotechnology

Effects of Culture Substrates on Antioxidant Activities of Extracts from Ganoderma lucidum (Rei-shi)

Metadata-grounded summary: This journal article indexes research on Ganoderma lucidum in Mushroom Science and Biotechnology in 2004. MycoData maps the paper to oncology, immune support, metabolic health, liver support based on its title, species context, article metadata, and study classification..

Shiitake · 2004 · Journal Article · Mycoscience

Estimation of viability of inner bark tissue of Quercus serrata, a substrate for log cultivation of Lentinula edodes, using the TTC assay method

Enoki · 2004 · Journal Article · Mycoscience

Influence of light on the morphological changes that take place during the development of the Flammulina velutipes fruit body

Metadata-grounded summary: This journal article indexes research on Flammulina velutipes in Mycoscience in 2004. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Enoki · 2004 · Research Article · Journal of Fujian Agriculture and Forestry University(Natural Science Edition)

Molecular marker for fruit-body color gene of Flammulina velutipes

Metadata-grounded summary: This research article indexes research on Flammulina velutipes in Journal of Fujian Agriculture and Forestry University(Natural Science Edition) in 2004. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Immune supportCognition & nervesEnergy & fatigue

Reishi · 2004 · Journal Article · Journal of Pharmacological Sciences

Polysaccharide Extract Isolated From Ganoderma lucidum Protects Rat Cerebral Cortical Neurons From Hypoxia/Reoxygenation Injury

The effect of polysaccharide extract isolated from Ganoderma lucidum (Gl-PS) on rat cortical neuronal cultures exposed to hypoxia/reoxygenation (H/R) was studied in vitro. Gl-PS (1, 10, 100 microg/ml) increased neuron viability following H/R as measured by the inhibition of MTT reduction..

Lion's Mane · 2004 · Journal Article · Carbohydrate polymers

Structure of polysaccharides from the fruiting body of Hericium erinaceus Pers.

Metadata-grounded summary: This journal article indexes research on Hericium erinaceus in Carbohydrate polymers in 2004. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Lion's Mane · 2004 · Research Article · Natural Product Research and Development

Study on chemical composition of hericium erinaceus polysaccharide HEP--2

Metadata-grounded summary: This research article indexes research on Hericium erinaceus in Natural Product Research and Development in 2004. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Almond Mushroom · 2004 · Journal Article · JOURNAL OF CHEMICAL ENGINEERING OF JAPAN

Submerged Culture of Agaricus blazei Mycelium in a Bubble Column Fermentor

Metadata-grounded summary: This journal article indexes research on Agaricus blazei in JOURNAL OF CHEMICAL ENGINEERING OF JAPAN in 2004. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Enoki · 2004 · Research Article · Hua zhong nong ye da xue xue bao = Journal Huazhong (Central China) Agricultural University

The polysaccharide produced from liquid culture of Flammulina velutipes

Metadata-grounded summary: This research article indexes research on Flammulina velutipes in Hua zhong nong ye da xue xue bao = Journal Huazhong (Central China) Agricultural University in 2004. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Maitake · 2003 · Journal Article · Shokubutsu Kojo Gakkaishi

Bio-Electric Potential under Light Stimuli of Grifola frondosa. (Part 3)

Metadata-grounded summary: This journal article indexes research on Grifola frondosa in Shokubutsu Kojo Gakkaishi in 2003. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Enoki · 2003 · Journal Article · Mushroom science and biotechnology

Double Stranded RNA Elements in the Cultivated Flammulina velutipes, Shinano No. 6

Metadata-grounded summary: This journal article indexes research on Flammulina velutipes in Mushroom science and biotechnology in 2003. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Shiitake · 2003 · Journal Article · Mushroom science and biotechnology

Effect of Temperature and Moisture Content on Competition between Graphostroma platystoma and Lentinula edodes on Branch Segment in Container

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in Mushroom science and biotechnology in 2003. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

Enoki · 2003 · Journal Article · Mycoscience

Electrophoretic karyotype of Flammulina velutipes and its variation among monokaryotic progenies

Metadata-grounded summary: This journal article indexes research on Flammulina velutipes in Mycoscience in 2003. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..