MycoData

Cordyceps sinensis, an important medicinal fungus in traditional Chinese medicine, has gained increasing attention for its diverse pharmacological activities, particularly its anti-inflammatory properties..

Immune supportCognition & nervesMetabolic healthGut & microbiome

High relevance

Cordyceps · 2026 · Review · Phytotherapy research: PTR

Biologically Active Ingredients and Underlying Mechanisms of Cordyceps in Treating Respiratory Diseases: A Comprehensive Review With Future Perspectives.

The incidence of respiratory diseases is increasing worldwide and imposes a significant health burden. Due to the complex etiology and diverse inducements of these diseases, existing therapies often struggle to control disease progression and reduce recurrence rates..

Immune supportRespiratory

High relevance

Nameko · 2026 · Review · RSC advances

Extraction, purification, structural characterization, bioactivities, and applications of Pholiota nameko polysaccharide: a review.

Pholiota nameko, an edible mushroom, is recognized for its significant medicinal properties and broad application potential. Pholiota nameko polysaccharide (PNP), a major bioactive component derived from this fungus, exhibits diverse biological activities, including anti-inflammatory, antioxidant, antitumor,….

OncologyImmune supportMetabolic health

High relevance

Enoki · 2025 · Review · Comprehensive reviews in food science and food safety

An Overview of Listeriosis Outbreak Investigations in the United States Linked to Imported Enoki Mushrooms and Associated Regulatory Activities, Research, and Food Safety Knowledge Gaps.

Foods implicated in listeriosis outbreaks continue to change over time. Historically, listeriosis outbreaks have been primarily linked to consumption of deli meat and dairy products.

High relevance

Cordyceps · 2025 · Review · Critical reviews in biotechnology

Chinese cordyceps products, geographic traceability and authenticity assessment: current status, challenges, and future directions.

Chinese cordyceps, a medicinal fungus and nutritional supplement native to the Tibetan Plateau, is highly celebrated for its potential health benefits and significant economic value. The quality of wild Chinese cordyceps varies across different production regions, resulting in considerable price differences..

High relevance

Cordyceps · 2025 · Review · Current nutrition reports

Ergogenic Aid by Cordyceps: Does It Work??

PURPOSE OF REVIEW: Supplements for exercise have gained significant attention among athletes and sports practitioners. Herbs with high bioactive content are commonly used to enhance exercise performance..

Immune supportEnergy & fatigue

High relevance

Cordyceps · 2025 · Review · Zeitschrift fur Naturforschung. C, Journal of biosciences

Ethnopharmacology and current conservational status of Cordyceps sinensis.

Cordyceps sinensis, known as the caterpillar fungus, constitutes an invaluable and irreplaceable part of traditional Chinese medicine (TCM) and is now gaining widespread global recognition and dedicated attention owing to both highly promising characteristics as well as grave dangers that are suggestive of an….

Cognition & nerves

High relevance

Nameko · 2025 · Review · Food science and biotechnology

Extraction, structure and bioactivities of polysaccharides from Pholiota nameko: a review.

Pholiota nameko, a famous edible mushroom, has broad application prospects in the field of health food development because of its high nutritional value, complex structure, and diverse biological activities..

Immune supportMetabolic health

High relevance

Cordyceps · 2025 · Review · Current pharmaceutical design

Immunopharmacological Insights into Cordyceps spp.: Harnessing Therapeutic Potential for Sepsis.

Cordyceps spp. (CS), a well-known medicinal mushroom that belongs to Tibetan medicine and is predominantly found in the high altitudes in the Himalayas.

Immune supportCognition & nervesLiver supportRespiratory

High relevance

Shiitake · 2025 · Preprint · journal metadata

Machine Vision and Deep Learning for Robotic Harvesting of Shiitake Mushrooms

Automation and computer vision are increasingly vital in modern agriculture, yet mushroom harvesting remains largely manual due to complex morphology and occluded growing environments..

Cognition & nervesEnergy & fatigue

High relevance

Cordyceps · 2025 · Review · International journal of molecular sciences

Preclinical Evidence of Withania somnifera and Cordyceps spp.: Neuroprotective Properties for the Management of Alzheimer's Disease.

Alzheimer's disease (AD) is considered one of the main pathologies of our time, whose incidence and prevalence are suggested to be strongly underestimated. AD presents as a complex neurodegenerative condition characterized by marked neuroinflammation and a significant decline in the cognitive and mnemonic functions of….

OncologyImmune supportCognition & nerves

High relevance

Cordyceps · 2025 · Review · Life (Basel, Switzerland)

The Genus Cordyceps Sensu Lato: Their Chemical Constituents, Biological Activities, and Therapeutic Effects on Air Pollutants Related to Lung and Vascular Diseases.

Air pollutants are significant environmental factors that contribute to the exacerbation of respiratory, cardiopulmonary, and skin diseases in East Asia, and their impact is based on particle size..

Immune supportSkin & hydrationRespiratory

High relevance

Cordyceps · 2025 · Preprint · journal metadata

Three-Dimensional Structural Heteromorphs of Mating-Type Proteins in Hirsutella sinensis and the Natural Cordyceps sinensis Insect-Fungal Complex

The MAT1-1-1 and MAT1-2-1 proteins are essential for the sexual reproduction of Ophiocordyceps sinensis. Although Hirsutella sinensis has been postulated to be the sole-anamorph of O..

High relevance

Cordyceps · 2024 · Review · Critical reviews in biotechnology

Bioactive compounds from Cordyceps and their therapeutic potential.

The Clavicipitaceae family's largest and most diverse genus is Cordyceps. They are most abundant and diverse in humid temperate and tropical forests and have a wide distribution in: Europe, North America, and East and Southeast Asian countries, particularly: Bhutan, China, Japan, Nepal, Korea, Thailand, Vietnam,….

OncologyImmune support

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Cordyceps · 2024 · Review · Journal of ethnopharmacology

Cordyceps: Alleviating ischemic cardiovascular and cerebrovascular injury - A comprehensive review.

ETHNOPHARMACOLOGICAL RELEVANCE: Cordyceps has a long medicinal history as a nourishing herb in traditional Chinese medicine (TCM). Ischemic cardio-cerebrovascular diseases (CCVDs), including cerebral ischemic/reperfusion injury (CI/RI) and myocardial ischemic/reperfusion injury (MI/RI), are major contributors to….

OncologyImmune supportCognition & nervesEnergy & fatigue

High relevance

Almond Mushroom · 2024 · Review · Global spine journal

Efficacy and Outcome Measurement of iFactor/ABM/P-15 in Lumbar Spine Surgery: A Systematic Review.

STUDY DESIGN: Systematic Review. OBJECTIVES: To determine the efficacy and overall outcomes of iFactor/ABM/P-15 following lumbar spine surgery.

High relevance

Cordyceps · 2024 · Review · Journal of industrial microbiology & biotechnology

Enhancement of bioactive metabolites from solid-state fermentation of Cordyceps fungus using various substrates on ameliorating oxidative stress to liver health.

Cordyceps, a genus of Ascomycetes, represents a group of fungi that has attracted considerable attention from both the scientific community and practitioners of traditional medicine..

Liver support

High relevance

Cordyceps · 2024 · Review · Journal of chromatography. A

Insights into the methods for separation and chromatographic determination of nucleotides/nucleosides in Cordyceps spp.

Cordyceps genus is entomopathogenic mushrooms that have traditionally been used in ethnomedicine in Asian countries. Nucleosides (Ns), nucleotide(Nt), Nucleobases (Nb) and their analogues play a critically physiological role and have a great potential in drug development, such as pentostatin and cordycepin (COR)..

Skin & hydration

High relevance

Cordyceps · 2024 · Preprint · journal metadata

Mutations and Differential Transcription of Mating-Type and Pheromone Receptor Genes in Hirsutella sinensis and Natural Cordyceps sinensis

The sexual reproduction of ascomycetes is controlled by the mating-type(MAT) locus. (Pseudo)homothallic reproduction has been hypothesized based on genetic data from Hirsutella sinensis (Genotype #1 of Ophiocordyceps sinensis)..

High relevance

Cordyceps · 2020 · Research Article · Molecules (Basel, Switzerland)

Analysis of Volatile Components in Different Ophiocordyceps sinensis and Insect Host Products.

The artificial production of Ophiocordyceps sinensis mycelia and fruiting bodies and the Chinese cordyceps has been established. However, the volatile components from these O.

High relevance

Almond Mushroom · 2020 · Research Article · Food science & nutrition

Enhancement of glucose homeostasis through the PI3K/Akt signaling pathway by dietary with Agaricus blazei Murrill in STZ-induced diabetic rats.

Agaricus blazei Murrill (ABM) is an edible fungus. This study investigated the protective role of ABM fruiting body against streptozotocin (STZ)-induced diabetic rats.

Metabolic healthLiver support

High relevance

Almond Mushroom · 2020 · Randomized Controlled Trial · The spine journal: official journal of the North American Spine Society

Randomized double blind clinical trial of ABM/P-15 versus allograft in noninstrumented lumbar fusion surgery.

BACKGROUND CONTEXT: Due to poor bone stock in the elderly, a noninstrumented fusion is commonly performed in Scandinavia when instability is present. Allograft bone is often used as graft extender with consequent low fusion rates..

High relevance

Shiitake · 2016 · Review · Pharmacognosy reviews

The Unexplored Anticaries Potential of Shiitake Mushroom.

Keeping an eye the escalating costs of dental services, the treatment cost of the consequences of dental caries can be reduced to manageable proportions by preventive measures aimed at decreasing the prevalence. One such measure is by increasing the consumption of caries preventive foods..

OncologySkin & hydrationRespiratory

High relevance

Shiitake · 2026 · Evaluation Study · Food chemistry

Bioconversion-type selenium-enriched kombucha fermentation broth: preservation enhancement and organic selenium enrichment regulation in Lentinula edodes.

Post-harvest deterioration of shiitake mushrooms causes substantial economic losses, while conventional methods lack nutritional enhancement. This study developed a selenium-enriched kombucha fermentation preservation (SKFP) system that simultaneously extends shelf life and improves selenium biofortification..

High relevance

Reishi · 2026 · Journal Article · Journal of basic microbiology

Effects of Biochar on Physiological and Biochemical Characteristics of Ganoderma lingzhi (Lingzhi) During Cultivation.

This study focused on Ganoderma mycelium as the experimental subject and conducted a systematic investigation into the effects of varying the addition ratio of biomass charcoal in the cultivation substrate..

High relevance

Oyster Mushroom · 2026 · Research Article · PLoS genetics

Establishment of a congenic strain for the oyster mushroom reveals the structure and evolution of mating-type loci.

Pleurotus ostreatus, a widely cultivated edible oyster mushroom, is an ecologically versatile species with applications in biotechnology, agriculture, and food production. It functions as a decomposer and in nutrient-limited conditions it enhances its survival by using a potent toxin to prey on nematodes..

High relevance

Maitake · 2026 · Journal Article · Journal of complementary & integrative medicine

Evaluating the anticancer potential of black maitake extract in A375 human malignant melanoma cells.

UNLABELLED: Melanoma is one of the deadliest skin cancers, characterized by high metastatic potential and poor prognosis in advanced stages. While chemotherapeutic agent temozolomide (TMZ) is the standard treatment, its clinical utility is hindered by toxicity and limited specificity..

OncologyEnergy & fatigueSkin & hydration

High relevance

Shiitake · 2026 · Research Article · Foods (Basel, Switzerland)

Regulation of Pickling Efficiency and Physicochemical Properties of Reduced-Sodium Chicken Breast Using Shiitake Mushroom Extract and Ultrasound-Assisted Marination.

Reducing sodium in poultry products often compromises texture and water-holding capacity. This study investigated the interactive effects of shiitake (Lentinula edodes) mushroom extract (SME) and ultrasound (US) on mitigating these defects in reduced-sodium chicken breast..

High relevance

Cordyceps · 2025 · Research Article · Journal of microbiology and biotechnology

Exploring the Therapeutic Potential of Cordyceps Mushroom on SARS-CoV-2 Using Virtual Screening against Mpro and In Vitro Validation of Cordycepin.

Pathogenic coronavirus, including COVID-19, threatens human health, and there have been strong demands for efficient therapeutics. Cordyceps militaris is a medicinal mushroom that has long been used for immune enhancement, anticancer, and antiviral effects.

OncologyImmune supportRespiratory

High relevance

Cordyceps · 2025 · Research Article · Insects

Quantifying Potentially Suitable Geographical Habitat Changes in Chinese Caterpillar Fungus with Enhanced MaxEnt Model.

Chinese Caterpillar Fungus (CCF) is a fungal-insect complex formed by the underground larvae of certain species in the family Hepialidae parasitized by Ophiocordyceps sinensis (Berk.) (G.H.Sung, J.M.Sung, Hywel-Jones & Spatafora). It is a precious Chinese herbal medicine with significant medicinal value..

High relevance

Cordyceps · 2025 · Research Article · Journal of fungi (Basel, Switzerland)

Three-Dimensional Structural Heteromorphs of Mating-Type Proteins in Hirsutella sinensis and the Natural Cordyceps sinensis Insect-Fungal Complex.

The MAT1-1-1 and MAT1-2-1 proteins are essential for the sexual reproduction of Ophiocordyceps sinensis. Although Hirsutella sinensis has been postulated to be the sole anamorph of O..

High relevance

Oyster Mushroom · 2024 · Research Article · Scientific reports

Dietary incorporation of brown seaweed spent oyster mushroom substrate alters growth performance, physiological responses and meat quality parameters in Boschveld roosters.

Use of brown seaweed (Ecklonia maxima) as a nutraceutical source in indigenous chicken diets is limited by high dietary fibre levels. Inoculating seaweeds with oyster mushroom (Pleurotus ostreatus) spawn (OMS) could enhance the utility of the spent mushroom substrate (SMS)..

Energy & fatigue

High relevance

Maitake · 2024 · Journal Article · Biological & pharmaceutical bulletin

Maitake Beta-Glucan Enhances the Therapeutic Effect of Trastuzumab via Antibody-Dependent Cellular Cytotoxicity and Complement-Dependent Cytotoxicity

Trastuzumab, an anti-HER2 monoclonal antibody, is the mainstay treatment for of HER2-positive breast cancer. However, trastuzumab resistance is often observed during treatment.

OncologyImmune support

High relevance

Cordyceps · 2024 · Research Article · Biology

Mutations and Differential Transcription of Mating-Type and Pheromone Receptor Genes in Hirsutella sinensis and the Natural Cordyceps sinensis Insect-Fungi Complex.

Sexual reproduction in ascomycetes is controlled by the mating-type (MAT) locus. (Pseudo)homothallic reproduction has been hypothesized on the basis of genetic data from Hirsutella sinensis (Genotype #1 of Ophiocordyceps sinensis)..

High relevance

Chaga · 2024 · Research Article · Oxidative medicine and cellular longevity

Synergistic Cytotoxicity of Extracts of Chaga Mushroom and Microalgae against Mammalian Cancer Cells In Vitro.

Chaga mushroom (Inonotus obliquus) contains bioactive metabolites and has been used to treat various ailments, including cancer. Similarly, marine microalgae are considered a sustainable food supplement with anticancer and antioxidant properties..

Oncology

High relevance

Chaga · 2024 · Research Article · Journal of fungi (Basel, Switzerland)

The Effect of Green Extraction Technologies on the Chemical Composition of Medicinal Chaga Mushroom Extracts.

The mushroom industry should implement green extraction technologies; however, there is not enough information on the differences between these techniques expressed as the chemical composition of the resulting extract..

Immune supportMetabolic health

High relevance

Oyster Mushroom · 2024 · Research Article · Poultry science

The influence of dietary supplementation with oyster mushroom waste on laying hens' performance, egg quality and immune parameters.

The objective of the present study was to evaluate the effects of dietary supplementation with oyster mushroom (Pleurotus ostreatus) waste (OMW) on performance, egg quality, fatty acid (FA) profile and oxidative stability, serum and yolk cholesterol and immune parameters of laying hens..

Immune supportEnergy & fatigueMetabolic health

High relevance

Oyster Mushroom · 2024 · Research Article · International journal of molecular sciences

Transmission of Oyster Mushroom Spherical Virus to Progeny via Basidiospores and Horizontally to a New Host Pleurotus floridanus.

Mycoviruses are usually transmitted horizontally via hyphal anastomosis and vertically through sporulation in natural settings. Oyster mushroom spherical virus (OMSV) is a mycovirus that infects Pleurotus ostreatus, with horizontal transmission via hyphal anastomosis..

Respiratory

High relevance

Cordyceps · 2023 · Randomized Controlled Trial, Veterinary · Archives of Razi Institute

Effect of Adding Cordyceps sinensis Extract and Probiotic to the Diet on Productive Performance of Broiler.

Following a substantial increase in poultry breeding, the demand for their meat has risen. Poultry meat is one of the primary sources of protein in human nutrition, which contributes to food security..

Energy & fatigueMetabolic healthGut & microbiome

High relevance

Cordyceps · 2022 · Randomized Controlled Trial · International journal of medicinal mushrooms

Efficacy of Cordyceps cicadae (Ascomycota) Mycelium Supplementation for Amelioration of Dry Eye Symptoms: A Randomized, Double-Blind Clinical Pilot Study.

Dry eye disease (DED), a multifactorial inflammatory ocular surface disorder, affects up to 50% of individuals over 50 years old worldwide and is one of the most common reasons for seeking ophthalmologic care..

Immune support

High relevance

Cordyceps · 2022 · Research Article · Molecules (Basel, Switzerland)

High Throughput Identification of the Potential Antioxidant Peptides in Ophiocordyceps sinensis.

Ophiocordyceps sinensis, an ascomycete caterpillar fungus, has been used as a Traditional Chinese Medicine owing to its bioactive properties. However, until now the bio-active peptides have not been identified in this fungus.

High relevance

Oyster Mushroom · 2022 · Randomized Controlled Trial · Scientific reports

Primordial initiation, yield and yield component traits of two genotypes of oyster mushroom (Pleurotus spp.) as affected by various rates of lime.

Mushrooms are fleshy fungi valued globally for their nutritional and medical benefits. The study was conducted at Ebonyi State University Mushroom Center, Abakaliki, to determine an optimum level of limestone (CaCO3) on the genotypes for maximum growth and yield..

High relevance

Oyster Mushroom · 2021 · Journal Article · International journal of food science & technology

Effects of ultraviolet‐C irradiation on the physicochemical properties of polysaccharide films prepared from the stalk base of oyster mushrooms (Pleurotus ostreatus)

The effects of ultraviolet (UV)‐C irradiation on the physicochemical properties of oyster mushroom polysaccharide (OMP) films were investigated. The prepared OMP films were subjected to UV‐C treatment (5.4 kJ m⁻²)..

Immune supportSkin & hydration

High relevance

Cordyceps · 2020 · Brief Report · Genome biology and evolution

A New High-Quality Draft Genome Assembly of the Chinese Cordyceps Ophiocordyceps sinensis.

Ophiocordyceps sinensis (Berk.) is an entomopathogenic fungus endemic to the Qinghai-Tibet Plateau. It parasitizes and mummifies the underground ghost moth larvae, then produces a fruiting body..

High relevance

Cordyceps · 2020 · Research Support, Non U.S. Gov'T · PloS one

Analysis of reference genes stability and histidine kinase expression under cold stress in Cordyceps militaris.

The development of fungal fruiting bodies from a hyphal thallus is inducible under low temperature (cold stress). The molecular mechanism has been subject to surprisingly few studies.

High relevance

Oyster Mushroom · 2020 · Research Support, Non U.S. Gov'T · Bioorganic chemistry

Antimicrobial chloro-hydroxylactones derived from the biotransformation of bicyclic halolactones by cultures of Pleurotus ostreatus.

The aim of this research was to test the ability of cultures of edible fungi to biotransform three bicyclic halolactones. The substrates (2-chloro-, 2-bromo- and 2-iodo-4,4,6,7-tetramethyl-9-oxabicyclo[4.3.0]nonan-8-one) received by means of synthesis were transformed by oyster mushroom Pleurotus ostreatus and edible….

High relevance

Cordyceps · 2020 · Comparative Study · International journal of medicinal mushrooms

Carotenoid Production by Caterpillar Medicinal Mushrooms, Cordyceps militaris (Ascomycetes), under Different Culture Conditions.

Cordyceps militaris, a well-known edible and medicinal species, is a potential source of natural carotenoids. The optimized conditions for carotenoid production are important for high-quality cultivation since carotenoid contents are the key factors for the appearance of fruiting bodies..

Energy & fatigue

High relevance

Cordyceps · 2020 · Research Support, Non U.S. Gov'T · Biomolecules

Cmfhp Gene Mediates Fruiting Body Development and Carotenoid Production in Cordyceps militaris.

Cordyceps militaris fruiting bodies contain a variety of bioactive components that are beneficial to the human body. However, the low yield of fruiting bodies and the low carotenoid content in C.

High relevance

Cordyceps · 2020 · Research Support, Non U.S. Gov'T · Environmental microbiology

CmVVD is involved in fruiting body development and carotenoid production and the transcriptional linkage among three blue-light receptors in edible fungus Cordyceps militaris.

Fruiting body development and carotenoid production are light-induced in Cordyceps militaris. Our previous studies have shown that two blue-light receptors, CmWC-1 and CmCRY-DASH, regulate fruiting body development and secondary metabolism.

Immune support

High relevance

King Oyster · 2020 · Comparative Study · International journal of medicinal mushrooms

Comparative Neuroprotective, Anti-Inflammatory and Neurite Outgrowth Activities of Extracts of King Oyster Mushroom, Pleurotus eryngii (Agaricomycetes).

Pleurotus eryngii (king oyster mushroom) is a renowned culinary mushroom with various medicinal properties that may be beneficial for health maintenance and disease prevention. However, its effect on the nervous system remains elusive.

Immune supportCognition & nerves