MycoData

Cognition & nervesEnergy & fatigueLiver support

Almond Mushroom · 2025 · Randomized Controlled Trial · Behavioural and cognitive psychotherapy

Combining internet-delivered cognitive behavioural therapy and attention bias modification for reducing depressive symptoms in firefighters: a randomized controlled trial.

BACKGROUND: Firefighters are frequently exposed to traumatic events and stressful environments and are at particularly high risk of depressive symptoms. AIMS: The present study aimed to examine the impact of a combined internet-delivered cognitive behavioral therapy (iCBT) and attention bias modification (ABM)….

OncologyImmune supportMetabolic healthLiver support

Niu-Chang-Chih · 2025 · Review · Naunyn-Schmiedeberg's archives of pharmacology

Unlocking the biological potential of methyl antcinate A: a new frontier in cancer and inflammation application.

Antrodia camphorata is a valued and scarce parasitic mushroom that exclusively proliferates on the inner cavity wall of the endangered tree Cinnamomum kanehirai Hay (Lauraceae), endemic to Taiwan..

Almond Mushroom · 2025 · Randomized Controlled Trial · Drug and alcohol review

What hepatology clinicians and their patients with alcohol-related liver disease think of wearable alcohol biosensors to aid abstinence from alcohol: A qualitative study.

INTRODUCTION: We aimed to determine acceptability and feasibility of innovative wearable alcohol biosensor monitors (ABM) for patients with alcohol-related liver disease (ALD) and their clinicians..

OncologyImmune supportMetabolic healthLiver support

Reishi · 2024 · Review · Mycology

Bibliometric, taxonomic, and medicinal perspectives of Ganoderma neo-japonicum Imazeki: A mini review.

Ganoderma, a traditional medicine in Asian countries, has been used to prevent and treat various ailments for centuries. Ganoderma neo-japonicum (synonym Ganoderma bambusicola), also known as purple Lingzhi, is a species that is currently underutilised when compared to Ganoderma lucidum (Lingzhi)..

OncologyLiver supportRespiratory

Cordyceps · 2015 · Research Support, Non U.S. Gov'T · Journal of microbiology (Seoul, Korea)

Anti-tumor effect of Cordyceps militaris in HCV-infected human hepatocarcinoma 7.5 cells.

Cordyceps extract has been reported to have various pharmacological activities including an anti-cancer effect. We investigated the inhibitory effect of Cordyceps militaris on hepatitis C virus-infected human hepatocarcinoma 7.5 cells (J6/JFH1-huh 7.5 cells)..

Cordyceps · 2015 · Research Support, Non U.S. Gov'T · Carbohydrate polymers

Antihyperlipidemic and hepatoprotective activities of residue polysaccharide from Cordyceps militaris SU-12.

Cordyceps militaris has been artificially cultivated in China, and the great amounts of produced medium residue were discarded after the harvest. The aims of this work were to analyze the structure of the residue polysaccharide (RPS) of C..

Chaga · 2015 · Research Support, Non U.S. Gov'T · Journal of ethnopharmacology

Chemical characterization and biological activity of Chaga (Inonotus obliquus), a medicinal "mushroom".

ETHNOPHARMACOLOGICAL RELEVANCE: In Russian traditional medicine, an extract from the mushroom Inonotus obliquus (Fr.) Pil´at is used as an anti-tumor medicine and diuretic. It has been reported that Inonotus obliquus has therapeutic effects, such as anti-inflammatory, immuno-modulatory and hepatoprotective effects..

Almond Mushroom · 2015 · Research Support, Non U.S. Gov'T · Molecular medicine reports

Chitosan oligosaccharides in combination with Agaricus blazei Murill extract reduces hepatoma formation in mice with severe combined immunodeficiency.

Chitosan and Agaricus blazei Murill (ABM) extracts possess antitumor activities. The aim of the present study was to investigate whether chitosan, ABM extract or the two in combination were effective against tumors in tumor‑bearing mice..

Maitake · 2015 · Research Support, Non U.S. Gov'T · Food & function

Hypoglycemic effects of Grifola frondosa (Maitake) polysaccharides F2 and F3 through improvement of insulin resistance in diabetic rats.

Our laboratory has previously demonstrated that Grifola frondosa polysaccharides (GFPs) showed hypoglycemic effects. This study aimed to investigate which polysaccharide-enriched fractions of GFPs were the main active constituents, and to disclose their hypoglycemic mechanism..

OncologyMetabolic healthLiver support

Wood Ear · 2015 · Research Support, Non U.S. Gov'T · International journal of medicinal mushrooms

Hypolipidemic and Hepatic Steatosis Preventing Activities of the Wood Ear Medicinal Mushroom Auricularia auricula-judae (Higher Basidiomycetes) Ethanol Extract In Vivo and In Vitro.

Obesity, a rapidly growing threat to human health worldwide, is responsible for a large proportion of the total burden of disease. Therefore, obesity control could be a vital scheme to prevent many diseases..

OncologyMetabolic healthGut & microbiomeLiver support

King Oyster · 2015 · Research Support, Non U.S. Gov'T · Asian Pacific journal of cancer prevention: APJCP

Inhibition of Azoxymethane-induced Colorectal Aberrant Crypt Foci in Mice Fed a High-fat Diet by Pleurotus eryngii (Eringi) and Hypsizygus marmoreus (Bunashimeji).

Obesity markedly increases the risk of colorectal cancer. Recently, the preventive effects of edible mushrooms on triglyceride elevation and visceral fat accumulation have been reported..

OncologyImmune supportLiver supportRespiratory

King Oyster · 2014 · Research Support, Non U.S. Gov'T · Journal of the science of food and agriculture

Antiproliferative and immunostimulatory activity of a protein from Pleurotus eryngii.

BACKGROUND: Currently, the use of mushrooms as functional foods, nutraceuticals or phytopharmaceuticals source has risen. In contrast, the possible cellular cytotoxicity and immunostimulatory activity of Pleurotus eryngii (DC.

King Oyster · 2014 · Research Support, Non U.S. Gov'T · Food & function

Chemical composition of Pleurotus eryngii polysaccharides and their inhibitory effects on high-fructose diet-induced insulin resistance and oxidative stress in mice.

High intake of dietary fructose exerts a number of adverse metabolic effects. The present study investigates the preventive effects of Pleurotus eryngii polysaccharides (PEP), which showed powerful antioxidant activity in vitro, on insulin resistance and oxidative stress in mice fed a high-fructose diet..

OncologyImmune supportMetabolic healthLiver support

Niu-Chang-Chih · 2014 · Research Support, Non U.S. Gov'T · TheScientificWorldJournal

Effect of Antrodia camphorata on inflammatory arterial thrombosis-mediated platelet activation: the pivotal role of protein kinase C.

Antrodia camphorata is a rare Taiwanese medicinal mushroom. Antrodia camphorata extract has been reported to exhibit antioxidant, anti-inflammation, antimetastasis, and anticancer activities and plays a role in liver fibrosis, vasorelaxation, and immunomodulation..

Energy & fatigueMetabolic healthLiver support

Cordyceps · 2014 · Research Support, Non U.S. Gov'T · Journal of ethnopharmacology

Effect of Cordyceps militaris extract and active constituents on metabolic parameters of obesity induced by high-fat diet in C58BL/6J mice.

ETHNOPHARMACOLOGICAL RELEVANCE: Cordyceps species which is well-known as 'winter worm summer grass' has long been used as tonics and stimulants to enhance energy, exhibiting a potential for energy metabolism. Clinical trials have suggested their beneficial effect on lipid metabolic disorders such as hyperlipidemia..

Enoki · 2014 · Research Support, Non U.S. Gov'T · BioMed research international

Hypolipidemic and antioxidant activity of enoki mushrooms (Flammulina velutipes).

According to the literatures, Flammulina velutipes contains biologically active components such as dietary fiber, polysaccharide, and mycosterol, whose effects in reducing blood sugar, blood pressure, and cholesterol have been proven..

Cordyceps · 2014 · Research Support, Non U.S. Gov'T · BioMed research international

Studies on the antidiabetic activities of Cordyceps militaris extract in diet-streptozotocin-induced diabetic Sprague-Dawley rats.

Due to substantial morbidity and high complications, diabetes mellitus is considered as the third "killer" in the world. A search for alternative antidiabetic drugs from herbs or fungi is highly demanded..

Almond Mushroom · 2014 · Research Support, Non U.S. Gov'T · BioMed research international

The protective effect of Agaricus blazei Murrill, submerged culture using the optimized medium composition, on alcohol-induced liver injury.

Agaricus blazei Murrill (ABM), an edible mushroom native to Brazil, is widely used for nonprescript and medicinal purposes. Alcohol liver disease (ALD) is considered as a leading cause for a liver injury in modern dietary life, which can be developed by a prolonged or large intake of alcohol..

Lion's Mane · 2013 · Research Support, Non U.S. Gov'T · BMC complementary and alternative medicine

Antihyperglycemic and antihyperlipidemic activities of aqueous extract of Hericium erinaceus in experimental diabetic rats.

BACKGROUND: Hericium erinaceus, as a commonly used medicine or food, has attracted much attention due to its health effects when used as a home remedy for some diseases..

Immune supportLiver support

Yellow Morel · 2013 · Research Support, Non U.S. Gov'T · Food & function

Evaluation of the antioxidant activity of extracellular polysaccharides from Morchella esculenta.

Morchella esculenta, an edible medicinal mushroom native to China, is recognized as an unparalleled resource of healthy foods and drug discovery. This study firstly investigated the antioxidant activity of Morchella esculenta extracellular polysaccharides (MEEP)..

Immune supportGut & microbiomeLiver support

Almond Mushroom · 2013 · Research Support, Non U.S. Gov'T · In vivo (Athens, Greece)

Extract of medicinal mushroom Agaricus blazei Murill enhances the non-specific and adaptive immune activities in BALB/c mice.

Agaricus blazei Murill (AbM) is traditionally used against a wide range of conditions such as ulcerative colitis, Crohn's disease, foot-and-mouth disease and chronic hepatitis C infection. In this study, we evaluated the immunomodulatory effects of AbM..

King Oyster · 2013 · Research Support, Non U.S. Gov'T · Protein and peptide letters

Isolation of a phytase with distinctive characteristics from an edible mushroom, Pleurotus eryngii.

From the fresh fruiting bodies of the mushroom Pleurotus eryngii a phytase with a molecular mass of 14 kDa was isolated. The isolation protocol entailed ion exchange chromatography on DEAE-cellulose and CM-cellulose, affinity chromatography on Affi-gel blue gel, and ion exchange chromatography on Q-Sepharose..

OncologyLiver support

Maitake · 2013 · Research Support, Non U.S. Gov'T · International journal of medicinal mushrooms

MT-α-glucan from the fruit body of the maitake medicinal mushroom Grifola frondosa (higher Basidiomyetes) shows protective effects for hypoglycemic pancreatic β-cells.

The hypoglycemic effect of an α-glucan (designated here as MT-α-glucan) from the fruit body of the Maitake medicinal mushroom, Grifola frondosa, on a murine type 2 diabetes mellitus (T2DM) model was evaluated..

OncologyImmune supportMetabolic healthLiver support

Mesima · 2013 · Research Support, Non U.S. Gov'T · Journal of ethnopharmacology

Polysaccharide from Phellinus linteus induces S-phase arrest in HepG2 cells by decreasing calreticulin expression and activating the P27kip1-cyclin A/D1/E-CDK2 pathway.

ETHNOPHARMACOLOGY RELEVANCE: Our previous study showed that the proteoglycan P1 from Phellinus linteus (Mesima) exhibits significant anti-tumor activity against human hepatocellular carcinoma cells (HepG2); however, its molecular mechanism remains unknown..

Almond Mushroom · 2012 · Research Support, Non U.S. Gov'T · Integrative cancer therapies

An extract of Agaricus blazei Murill administered orally promotes immune responses in murine leukemia BALB/c mice in vivo.

PURPOSE: The edible mushroom (fungus) Agaricus blazei Murill (ABM) is a health food in many countries. Importantly, it has been shown to have antitumor and immune effects.

OncologyImmune supportLiver supportRespiratory

King Oyster · 2012 · Research Support, Non U.S. Gov'T · International journal of nanomedicine

Delivery of a transforming growth factor β-1 plasmid to mesenchymal stem cells via cationized Pleurotus eryngii polysaccharide nanoparticles.

The objective of this study was to investigate the use of cationized Pleurotus eryngii polysaccharide (CPEPS) as a nonviral gene delivery vehicle to transfer plasmid DNA encoding transforming growth factor beta-1 (pTGF-β1) into mesenchymal stem cells (MSCs) in vitro. Crude P..

King Oyster · 2012 · Research Support, Non U.S. Gov'T · Journal of agricultural and food chemistry

Effect of Pleurotus eryngii stalk residue on the oxidative status and meat quality of broiler chickens.

Pleurotus eryngii stalk residue (PESR) is a byproduct of the edible portion of the fruiting body. The present study was conducted to evaluate the effects of PESR on the oxidative status and meat quality of broilers..

Cognition & nervesMetabolic healthGut & microbiomeLiver support

Almond Mushroom · 2012 · Research Support, Non U.S. Gov'T · In vivo (Athens, Greece)

Evaluation of genotoxicity and subclinical toxicity of Agaricus blazei Murrill in the Ames test and in histopathological and biochemical analysis.

This study was conducted in order to assess the safety and tolerability of Agaricus blazei Murrill (ABM) in general toxicological studies by Ames tests in vitro and in 28-day feeding toxicity experiments..

OncologyImmune supportMetabolic healthLiver support

Reishi · 2012 · Book · journal metadata

Lingzhi, Reishi

Metadata-grounded summary: This book indexes research on Ganoderma lucidum in 2012. MycoData maps the paper to oncology, immune support, metabolic health, liver support based on its title, species context, article metadata, and study classification..

Immune supportLiver support

Almond Mushroom · 2012 · Research Support, Non U.S. Gov'T · Experimental parasitology

Prophylactic or therapeutic administration of Agaricus blazei Murill is effective in treatment of murine visceral leishmaniasis.

The present study aimed to investigate the in vitro antileishmanial activity of five fractions obtained from Agaricus blazei water extract (AbM), namely, Fab1, Fab2, Fab3, Fab4, and Fab5; and use the selected leishmanicidal fraction to treat BALB/c mice infected with Leishmania chagasi..

Immune supportLiver support

Almond Mushroom · 2012 · Research Support, Non U.S. Gov'T · Parasitology research

Therapeutic efficacy induced by the oral administration of Agaricus blazei Murill against Leishmania amazonensis.

The development of therapeutic alternatives to treat leishmaniasis has received considerable attention. The present study aimed to investigate the efficacy of the Agaricus blazei Murill water extract (AbM) to treat BALB/c mice infected with Leishmania amazonensis.

Almond Mushroom · 2011 · Research Support, Non U.S. Gov'T · In vivo (Athens, Greece)

Agaricus blazei Murill extract abrogates CCl4-induced liver injury in rats.

Agaricus blazei Murill (ABM) is enriched with polysaccharides, lipids, vitamins, fibers and minerals. Many studies have shown that ABM possesses immune-enhancing and anti-tumor effects.

Almond Mushroom · 2011 · Research Support, Non U.S. Gov'T · In vivo (Athens, Greece)

Carbon tetrachloride-induced hepatotoxicity and its amelioration by Agaricus blazei Murrill extract in a mouse model.

This study was conducted to evaluate the hepatoprotective effect of Agaricus blazei Murrill extract (ABM) against experimentally induced carbon tetrachloride (CCl(4)) toxicity in male BALB/c mice..

OncologyImmune supportLiver supportRespiratory

Almond Mushroom · 2011 · Research Support, Non U.S. Gov'T · In vivo (Athens, Greece)

Possible reduction of hepatoma formation by Smmu 7721 cells in SCID mice and metastasis formation by B16F10 melanoma cells in C57BL/6 mice by Agaricus blazei murill extract.

Agaricus blazei Murill extract (ABM) has been reported to possess antitumor effects. In this study, the role of ABM in tumor growth and metastasis in vivo was evaluated in experimental Smmu 7721 hepatoma cells in severe combined immunodeficiency (SCID) mice and B16F10 melanoma cells lung metastasis in C57BL/6 mice..

Shiitake · 2010 · Research Support, Non U.S. Gov'T · Journal of medicinal food

Bioavailability of iron from cereal products enriched with dried shittake mushrooms (Lentinula edodes) as determined by iron regeneration efficacy method in female rats.

Lentinula edodes shiitake mushrooms are rich sources of iron, which in addition to their relatively high nutritive value are also characterized by high contents of biologically active components..

OncologyLiver supportRespiratory

Niu-Chang-Chih · 2010 · Patent · journal metadata

NEW COMPOUNDS ISOLATED FROM EXTRACT OF ANTRODIA CAMPHORATA

The present invention relates to a novel compound and use thereof, in particular to Antroquinonol B and Antroquinonol C isolated from Antrodia camphorata extracts which can effectively inhibit the growth of cancer cells..

Lion's Mane · 2010 · Research Support, Non U.S. Gov'T · Bioscience, biotechnology, and biochemistry

Yamabushitake Mushroom (Hericium erinaceus) Improved Lipid Metabolism in Mice Fed a High-Fat Diet

The effects of dietary Yamabushitake mushroom (Hericium erinaceus) on lipid metabolism were examined. C57BL/6J mice were fed a high-fat diet containing hot-water extract (HW-E) and an ethanol extract (EtOH-E) of Yamabushitake mushroom..