MycoData

ETHNOPHARMACOLOGICAL RELEVANCE: The immunomodulatory capacities of fresh Cordyceps militaris (FCM) and dry Cordyceps militaris (DCM) were compared. MATERIALS AND METHODS: In vivo immunomodulatory assay, different doses of FCM and DCM were orally administrated over a period of 15 days in a cyclophosphamide (CY) induced….

Immune support

High relevance

Almond Mushroom · 2013 · Research Support, Non U.S. Gov'T · International journal of biological macromolecules

Effects of extraction methods on the antioxidant activities of polysaccharides from Agaricus blazei Murrill.

Five polysaccharides were obtained from Agaricus blazei Murrill (ABM) through different extraction methods including hot water extraction, single enzyme extraction (pectinase, cellulase or papain) and compound enzymes extraction (cellulase:pectinase:papain)..

Immune support

High relevance

Enoki · 2013 · Research Support, Non U.S. Gov'T · PloS one

Enhancement of heterologous gene expression in Flammulina velutipes using polycistronic vectors containing a viral 2A cleavage sequence.

Agrobacterium tumefaciens-mediated transformation for edible mushrooms has been previously established. However, the enhancement of heterologous protein production and the expression of multi-target genes remains a challenge..

Respiratory

High relevance

Yellow Morel · 2013 · Research Support, Non U.S. Gov'T · Food & function

Evaluation of the antioxidant activity of extracellular polysaccharides from Morchella esculenta.

Morchella esculenta, an edible medicinal mushroom native to China, is recognized as an unparalleled resource of healthy foods and drug discovery. This study firstly investigated the antioxidant activity of Morchella esculenta extracellular polysaccharides (MEEP)..

Immune supportLiver support

High relevance

Almond Mushroom · 2013 · Research Support, Non U.S. Gov'T · In vivo (Athens, Greece)

Extract of medicinal mushroom Agaricus blazei Murill enhances the non-specific and adaptive immune activities in BALB/c mice.

Agaricus blazei Murill (AbM) is traditionally used against a wide range of conditions such as ulcerative colitis, Crohn's disease, foot-and-mouth disease and chronic hepatitis C infection. In this study, we evaluated the immunomodulatory effects of AbM..

Immune supportGut & microbiomeLiver support

High relevance

King Oyster · 2013 · Research Support, Non U.S. Gov'T · Brazilian journal of microbiology: [publication of the Brazilian Society for Microbiology]

Extraction and in vitro antioxidant activity of exopolysaccharide by Pleurotus eryngii SI-02.

The extraction parameters for Pleurotus eryngii SI-02 exopolysaccharide (EPS) produced during submerged culture were optimized using response surface methodology (RSM)..

Immune support

High relevance

King Oyster · 2013 · Research Support, Non U.S. Gov'T · PloS one

Genetic variability and population structure of the mushroom Pleurotus eryngii var. tuoliensis.

The genetic diversity of 123 wild strains of Pleurotus eryngii var. tuoliensis, which were collected from nine geographical locations in Yumin, Tuoli, and Qinghe counties in the Xinjiang Autonomous Region of China, was analysed using two molecular marker systems (inter-simple sequence repeat and start codon targeted)..

High relevance

King Oyster · 2013 · Research Support, Non U.S. Gov'T · Bioprocess and biosystems engineering

Identification of naphthalene metabolism by white rot fungus Pleurotus eryngii.

The use of biomaterials or microorganisms in PAHs degradation had presented an eye-catching performance. Pleurotus eryngii is a white rot fungus, which is easily isolated from the decayed woods in the tropical rain forest, used to determine the capability to utilize naphthalene, a two-ring polycyclic aromatic….

Energy & fatigueMetabolic health

High relevance

King Oyster · 2013 · Research Support, Non U.S. Gov'T · Biological & pharmaceutical bulletin

Improvement of Depression-Like Behavior and Memory Impairment with the Ethanol Extract of Pleurotus eryngii in Ovariectomized Rats

Ethanol extract of Pleurotus eryngii (DC.) QUÉL has estrogen-like activities that protect against bone loss caused by estrogen deficiency. In the present study, we investigated the effect of P.

Cognition & nervesEnergy & fatigueMetabolic health

High relevance

Lion's Mane · 2013 · Research Support, Non U.S. Gov'T · International journal of medicinal mushrooms

In vitro anti-Helicobacter pylori effects of medicinal mushroom extracts, with special emphasis on the Lion's Mane mushroom, Hericium erinaceus (higher Basidiomycetes).

Although the medicinal mushroom Hericium erinaceus is used extensively in traditional Chinese medicine to treat chronic superficial gastritis, the underlining pharmaceutical mechanism is yet to be fully understood..

Immune supportGut & microbiome

High relevance

King Oyster · 2013 · Research Support, Non U.S. Gov'T · Protein and peptide letters

Isolation of a phytase with distinctive characteristics from an edible mushroom, Pleurotus eryngii.

From the fresh fruiting bodies of the mushroom Pleurotus eryngii a phytase with a molecular mass of 14 kDa was isolated. The isolation protocol entailed ion exchange chromatography on DEAE-cellulose and CM-cellulose, affinity chromatography on Affi-gel blue gel, and ion exchange chromatography on Q-Sepharose..

OncologyLiver support

High relevance

King Oyster · 2013 · Brief Report · Mycobiology

Isolation of Fungal Pathogens to an Edible Mushroom, Pleurotus eryngii, and Development of Specific ITS Primers.

Fungal pathogens have caused severe damage to the commercial production of Pleurotus eryngii, the king oyster mushroom, by reducing production yield, causing deterioration of commercial value, and shortening shelf-life. Four strains of pathogenic fungi, including Trichoderma koningiopsis DC3, Phomopsis sp..

High relevance

Shiitake · 2013 · Research Support, Non U.S. Gov'T · Journal of medicinal food

Lentinula edodes (shiitake) modulates chemically induced mutagenesis by enhancing pitting.

This study was undertaken to understand how Lentinula edodes modulates in vivo mutagenesis induced by alkylating agents in bone marrow and peripheral blood as described in our previous article. Male Swiss mice were pretreated for 15 consecutive days with aqueous extracts prepared from L..

Immune support

High relevance

Maitake · 2013 · Research Support, Non U.S. Gov'T · International journal of medicinal mushrooms

MT-α-glucan from the fruit body of the maitake medicinal mushroom Grifola frondosa (higher Basidiomyetes) shows protective effects for hypoglycemic pancreatic β-cells.

The hypoglycemic effect of an α-glucan (designated here as MT-α-glucan) from the fruit body of the Maitake medicinal mushroom, Grifola frondosa, on a murine type 2 diabetes mellitus (T2DM) model was evaluated..

Metabolic healthLiver support

High relevance

Lion's Mane · 2013 · Research Support, Non U.S. Gov'T · International journal of medicinal mushrooms

Neurotrophic properties of the Lion's mane medicinal mushroom, Hericium erinaceus (Higher Basidiomycetes) from Malaysia.

Neurotrophic factors are important in promoting the growth and differentiation of neurons. Nerve growth factor (NGF) is essential for the maintenance of the basal forebrain cholinergic system.

OncologyCognition & nervesRespiratory

High relevance

King Oyster · 2013 · Research Support, Non U.S. Gov'T · Antonie van Leeuwenhoek

Pantoea beijingensis sp. nov., isolated from the fruiting body of Pleurotus eryngii.

Four Gram-negative-staining, facultatively anaerobic bacterial isolates were obtained from a fruiting body of the edible mushroom Pleurotus eryngii showing symptoms of soft rot disease in Beijing, China..

High relevance

Mesima · 2013 · Research Support, Non U.S. Gov'T · Journal of ethnopharmacology

Polysaccharide from Phellinus linteus induces S-phase arrest in HepG2 cells by decreasing calreticulin expression and activating the P27kip1-cyclin A/D1/E-CDK2 pathway.

ETHNOPHARMACOLOGY RELEVANCE: Our previous study showed that the proteoglycan P1 from Phellinus linteus (Mesima) exhibits significant anti-tumor activity against human hepatocellular carcinoma cells (HepG2); however, its molecular mechanism remains unknown..

OncologyImmune supportMetabolic healthLiver support

High relevance

Maitake · 2013 · Research Support, Non U.S. Gov'T · International journal of medicinal mushrooms

Purification and characterization of a novel small-molecule polysaccharide from the Maitake medicinal mushroom Grifola frondosa (higher Basidiomycetes).

A novel small-molecule polysaccharide with a molecular mass of 2.6 kDa, was isolated from the culinary-medicinal Maitake mushroom Grifola frondosa. GFPS is composed of fucose, rhamnose, galactose, glucose, and mannose; galactose, glucose, and mannose were the dominant monosaccharides..

OncologyImmune supportMetabolic health

High relevance

Almond Mushroom · 2013 · Research Support, Non U.S. Gov'T · Complementary therapies in medicine

Quality of life improvements among cancer patients in remission following the consumption of Agaricus blazei Murill mushroom extract.

OBJECTIVES: The aim of this preliminary clinical study was to assess if the daily intake of Agaricus blazei Murill (ABM) granulated powder (SSI Co., Ltd., Tokyo, Japan) for 6 months improved the quality of life (QOL) in cancer patients in remission. DESIGN: Open study..

Oncology

High relevance

Shiitake · 2013 · Brief Report · BMC research notes

Rapid genotyping by low-coverage resequencing to construct genetic linkage maps of fungi: a case study in Lentinula edodes.

BACKGROUND: Genetic linkage maps are important tools in breeding programmes and quantitative trait analyses. Traditional molecular markers used for genotyping are limited in throughput and efficiency..

High relevance

Shiitake · 2013 · Research Support, Non U.S. Gov'T · Journal of microbiology (Seoul, Korea)

Reduction of organic and inorganic selenium compounds by the edible medicinal basidiomycete Lentinula edodes and the accumulation of elemental selenium nanoparticles in its mycelium.

We report for the first time that the medicinal basidiomycete Lentinula edodes can reduce selenium from inorganic sodium selenite (Se(IV)) and the organoselenium compound 1,5-diphenyl-3-selenopentanedione-1,5 (DAPS-25) to the elemental state, forming spherical nanoparticles..

Energy & fatigue

High relevance

King Oyster · 2013 · Research Support, Non U.S. Gov'T · Carbohydrate polymers

Structural elucidation of a novel heteropolysaccharide from the fruiting bodies of Pleurotus eryngii.

A novel water-soluble heteropolysaccharide (PEPS1), with a molecular weight of 1.88×10(4) Da as determined by high performance liquid chromatography (HPLC), specifically size exclusion chromatography, was isolated from the fruiting bodies of Pleurotus eryngii by hot water extraction and further purification by DEAE….

Immune supportEnergy & fatigue

High relevance

King Oyster · 2013 · Research Support, Non U.S. Gov'T · International journal of medicinal mushrooms

Submerged cultivation of mycelium with high ergothioneine content from the culinary-medicinal king oyster mushroom Pleurotus eryngii (higher Basidiomycetes) and its composition.

The culinary-medicinal king oyster mushroom, Pleurotus eryngii, was used to produce mycelia with high ergothioneine content using a one-factor-at-a-time method. The optimal culture conditions for mycelia harvested at day 14 were 25°C, 10% inoculation rate, 2% glucose, 0.5% yeast extract, and no adjustment to the….

Metabolic health

High relevance

King Oyster · 2013 · Research Support, Non U.S. Gov'T · Food and chemical toxicology: an international journal published for the British Industrial Biological Research Association

Topical application of Pleurotus eryngii extracts inhibits 2,4-dinitrochlorobenzene-induced atopic dermatitis in NC/Nga mice by the regulation of Th1/Th2 balance.

Pleurotus eryngii is a nutritional and medicinal food rich in polysaccharides that enhance the host immune system as a response to various diseases. The present study investigated the effects of P..

Immune supportSkin & hydration

High relevance

Niu-Chang-Chih · 2012 · English Abstract · Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials

[Preliminary analysis of quality of Antrodia camphorata powder].

OBJECTIVE: To proceed a preliminary analysis of the quality of Antrodia camphorata powder. METHODS: The contents of water-soluble extract were detected according to the standards stated in Chinese Pharmacopoeia.

Immune support

High relevance

Yellow Morel · 2012 · English Abstract · Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials

[Study on the extraction of mycelium polysaccharides from selenium-rich Morchella esculenta with neutral proteinase method].

OBJECTIVE: To study the extraction conditions of mycelium polysaccharides from selenium-rich Morchella esculenta with neutral proteinase for increasing of yield. METHODS: On the basis of single factor tests, orthogonal experiment design was applied to analyze the influence of factors including enzyme dosage,….

Immune support

High relevance

Almond Mushroom · 2012 · Research Support, Non U.S. Gov'T · Integrative cancer therapies

An extract of Agaricus blazei Murill administered orally promotes immune responses in murine leukemia BALB/c mice in vivo.

PURPOSE: The edible mushroom (fungus) Agaricus blazei Murill (ABM) is a health food in many countries. Importantly, it has been shown to have antitumor and immune effects.

OncologyImmune supportLiver support

High relevance

Mesima · 2012 · Patent · journal metadata

ANTICANCER HEALTH FOOD CONTAINING PHELLINUS LINTEUS AND VEGETABLE WORMS

Disclosed is a health food containing extracts of Phellinus linteus and vegetable worms for preventing and treating cancer. The health food contains ethanol extract of the mixture containing the mycelia of the Phellinus linteus and vegetable worms at a ratio of 1:5 to 5:1..

OncologyImmune support

High relevance

Almond Mushroom · 2012 · Research Support, Non U.S. Gov'T · Food and chemical toxicology: an international journal published for the British Industrial Biological Research Association

Bioaccessibility of cadmium in fresh and cooked Agaricus blazei Murill assessed by in vitro biomimetic digestion system.

Bioaccessibility of cadmium (Cd) in fresh and cooked Agaricus blazei Murill (AbM) was studied by an in vitro biomimetic digestion system in this paper. The results showed that the Cd content in fresh AbM was 10.27 mg kg(-1) DM..

Gut & microbiome

High relevance

Wood Ear · 2012 · Comparative Study · International journal of medicinal mushrooms

Comparative antitumor activity of jelly ear culinary-medicinal mushroom, Auricularia auricula-judae (Bull.) J. Schrot. (higher basidiomycetes) extracts against tumor cells in vitro.

The present study compares the antitumor activity of extracts from Auricularia auricula-judae, Phellinus gilvus, Ganoderma lucidum, and 100 Korean wild plants in the P388D1 macrophage cell line. The antitumor activity of A.

OncologyImmune support

High relevance

Mesima · 2012 · Patent · journal metadata

COMPOSITION FOR IMMUNOSTIMULATION WHICH COMPRISES POLYSACCHARIDE FROM FERMENTED GINSENG WITH PHELLINUS LINTEUS TO ENHANCE THE IMMUNE FUNCTION

PURPOSE: An immunity activating composition containing polysaccharide separated from a phellinus linteus mycelial fermentation product of ginseng is provided to activate immune cells forming the internal immune system of a user for preventing the infection from viruses or bacteria..

Immune supportRespiratory

High relevance

King Oyster · 2012 · Research Support, Non U.S. Gov'T · International journal of nanomedicine

Delivery of a transforming growth factor β-1 plasmid to mesenchymal stem cells via cationized Pleurotus eryngii polysaccharide nanoparticles.

The objective of this study was to investigate the use of cationized Pleurotus eryngii polysaccharide (CPEPS) as a nonviral gene delivery vehicle to transfer plasmid DNA encoding transforming growth factor beta-1 (pTGF-β1) into mesenchymal stem cells (MSCs) in vitro. Crude P..

OncologyImmune supportLiver supportRespiratory

High relevance

Cordyceps · 2012 · Research Support, Non U.S. Gov'T · Applied microbiology and biotechnology

Determining novel molecular markers in the Chinese caterpillar fungus Ophiocordyceps sinensis by screening a shotgun genomic library.

The Chinese caterpillar fungus Ophiocordyceps sinensis, endemic to alpine regions on the Tibetan Plateau, is one of the most valuable medicinal fungi in the world..

High relevance

King Oyster · 2012 · Research Support, Non U.S. Gov'T · Biotechnology letters

Direct over-expression, characterization and H2O2 stability study of active Pleurotus eryngii versatile peroxidase in Escherichia coli.

The vpl2 gene, encoding versatile peroxidase (VP) from Pleurotus eryngii, was synthesized with codon optimization and cloned into vector-pET-32a(+) and over-expressed in Escherichia coli BL21(DE3)..

High relevance

Enoki · 2012 · Evaluation Study · Poultry science

Effect of Flammulina velutipes on spent-hen breast meat tenderization.

An experiment was carried out to investigate the effects of powdered vegetable dip sauces to improve the tenderness of spent-hen breast meat. Our overall purpose was to find lower-priced materials for the tenderization of spent-hen breast meat..

High relevance

King Oyster · 2012 · Research Support, Non U.S. Gov'T · Journal of agricultural and food chemistry

Effect of Pleurotus eryngii stalk residue on the oxidative status and meat quality of broiler chickens.

Pleurotus eryngii stalk residue (PESR) is a byproduct of the edible portion of the fruiting body. The present study was conducted to evaluate the effects of PESR on the oxidative status and meat quality of broilers..

Liver support

High relevance

King Oyster · 2012 · Research Support, Non U.S. Gov'T · Organic letters

Eryngiolide A, a cytotoxic macrocyclic diterpenoid with an unusual cyclododecane core skeleton produced by the edible mushroom Pleurotus eryngii.

Eryngiolide A (1), the first member of C20 diterpenoids with the skeleton deriving from a cyclododecane core fused with two γ-lactone units, was isolated from the solid culture of the edible mushroom Pleurotus eryngii. The structure of 1 was elucidated by extensive analysis of NMR spectra..

Oncology

High relevance

King Oyster · 2012 · Research Support, Non U.S. Gov'T · Current microbiology

Evaluation of genetic diversity among Chinese Pleurotus eryngii cultivars by combined RAPD/ISSR marker.

Pleurotus eryngii (DC. Ex.

High relevance

Almond Mushroom · 2012 · Research Support, Non U.S. Gov'T · In vivo (Athens, Greece)

Evaluation of genotoxicity and subclinical toxicity of Agaricus blazei Murrill in the Ames test and in histopathological and biochemical analysis.

This study was conducted in order to assess the safety and tolerability of Agaricus blazei Murrill (ABM) in general toxicological studies by Ames tests in vitro and in 28-day feeding toxicity experiments..

Cognition & nervesMetabolic healthGut & microbiomeLiver support

High relevance

Maitake · 2012 · Research Support, Non U.S. Gov'T · World journal of microbiology & biotechnology

Growth, fruiting and lignocellulolytic enzyme production by the edible mushroom Grifola frondosa (maitake).

Cultivation of specialty mushrooms on lignocellulosic wastes represents one of the most economical organic recycling processes. Compared with other cultivated mushrooms, very little is known about the nature of the lignocellulolytic enzymes produced by the edible and medicinal fungus Grifola frondosa, the parameters….

Immune supportGut & microbiome

High relevance

King Oyster · 2012 · Research Support, Non U.S. Gov'T · Journal of microbiology and biotechnology

Identification of mating type loci and development of SCAR marker genetically linked to the B3 locus in Pleurotus eryngii.

In order to estimate how diverse the mating types in Pleurotus eryngii from different regions are, pairings between monokaryons derived from inter- and intragroups were done. Sixteen and 15 alleles were identified at loci A and B from the 12 strains.

High relevance

Shiitake · 2012 · Research Support, Non U.S. Gov'T · Journal of microbiology (Seoul, Korea)

Immunoprophylactic effects of shiitake mushroom (Lentinula edodes) against Bordetella bronchiseptica in mice.

Antimicrobials are used as feed additives to improve growth performance and to prevent subclinical disease challenge in industrial animals. However, these drugs can lead to the development of resistant strains of bacteria.

OncologyImmune supportEnergy & fatigueMetabolic health

High relevance

King Oyster · 2012 · Research Support, Non U.S. Gov'T · Journal of medicinal food

Induction of a T-Helper 1 (Th1) immune response in mice by an extract from the Pleurotus eryngii (Eringi) mushroom.

To assess the effect of edible mushroom extracts on the induction of T-helper 1 (Th1) immunity, we examined differences in interferon-gamma (IFN-γ) and interleukin (IL)-4 production in mice induced by hot-water extracts of 15 species of edible mushroom..

Immune support

High relevance

Chaga · 2012 · Research Support, Non U.S. Gov'T · Fish & shellfish immunology

Inonotus obliquus containing diet enhances the innate immune mechanism and disease resistance in olive flounder Paralichythys olivaceus against Uronema marinum.

The present study describes the effect of diet supplementation with Chaga mushroom, Inonotus obliquus extract at 0%, 0.01%, 0.1%, and 1.0% levels on the innate humoral (lysozyme, antiprotease, and complement), cellular responses (production of reactive oxygen and nitrogen species and myeloperoxidase), and disease….

Immune supportEnergy & fatigue

High relevance

Reishi · 2012 · Book · journal metadata

Lingzhi, Reishi

Metadata-grounded summary: This book indexes research on Ganoderma lucidum in 2012. MycoData maps the paper to oncology, immune support, metabolic health, liver support based on its title, species context, article metadata, and study classification..

OncologyImmune supportMetabolic healthLiver support

High relevance

King Oyster · 2012 · Research Support, Non U.S. Gov'T · Fungal genetics and biology: FG & B

Nitric oxide alleviates heat stress-induced oxidative damage in Pleurotus eryngii var. tuoliensis.

High temperature is one of the major impediments limiting the growth and development of most edible fungi. While many efforts have been made in agricultural practice, the mechanism for resistance to high temperature remains elusive..

High relevance

King Oyster · 2012 · Research Support, Non U.S. Gov'T · Biotechnology letters

Nitric oxide is involved in the regulation of trehalose accumulation under heat stress in Pleurotus eryngii var. tuoliensis.

Little is known about the mechanism of how trehalose responds to various abiotic stresses although trehalose is considered as an important protectant in fungi. We investigated the role of nitric oxide (NO) in regulating trehalose accumulation during heat stress in Pleurotus eryngii var.

High relevance

Enoki · 2012 · Research Support, Non U.S. Gov'T · Zeitschrift fur Naturforschung. C, Journal of biosciences

Optimization of soluble organic selenium accumulation during fermentation of Flammulina velutipes mycelia.

Selenium is an essential nutrient with diverse physiological functions, and soluble organic selenium (SOS) sources have a higher bioavailability than inorganic selenium sources..

Metabolic health

High relevance

Chaga · 2012 · Research Support, Non U.S. Gov'T · Journal of ethnopharmacology

Orally administered aqueous extract of Inonotus obliquus ameliorates acute inflammation in dextran sulfate sodium (DSS)-induced colitis in mice.

ETHNOPHARMACOLOGICAL RELEVANCE: Chaga mushroom (Inonotus obliquus) has been used in folk medicine to treat several disorders through its various biological functions. I..

OncologyImmune supportMetabolic healthGut & microbiome

High relevance

King Oyster · 2012 · Research Support, Non U.S. Gov'T · Biotechnology letters

Polyethylene glycol-mediated transformation of fused egfp-hph gene under the control of gpd promoter in Pleurotus eryngii.

Pleurotus eryngii was transformed using a polyethylene glycol-mediated method. A plasmid, pEPUGH, containing a reporter gene (enhanced green fluorescent protein gene, egfp) and a positive selectable marker gene (hygromycin phosphotransferase gene, hph) was constructed..