MycoData

BACKGROUND: Lentinula edodes, known as shiitake, has been utilized as food, as well as, in popular medicine, moreover, compounds isolated from its mycelium and fruiting body have shown several therapeutic properties..

Immune supportRespiratory

High relevance

King Oyster · 2012 · Research Support, Non U.S. Gov'T · International journal of medicinal mushrooms

Preparation of culinary-medicinal king oyster mushroom Pleurotus eryngii-fermented products with high ergothioneine content and their taste quality.

Pleurotus eryngii (DC.: Fr.) Ouel. was used in solid-state fermentation to develop novel mushroom products with a high amount of ergothioneine.

High relevance

Snow Fungus · 2012 · Patent · journal metadata

PRODUCING METHOD OF EXTRACT OF TREMELLA FUCIFORMIS USING ENZYMES AND THE COMPOSITION FOR IMPROVING MEMORY STRENGTH COMPRISING THE EXTRACT

PURPOSE: A composition containing Tremella fuciformis extract is provided to improve yield and to recover neural cells. CONSTITUTION: A method for preparing Tremella fuciformis extract comprises: a step of performing hot water extraction of Tremella fuciformis under an acidic condition and a step of treating enzyme to….

Cognition & nerves

High relevance

King Oyster · 2012 · Research Support, Non U.S. Gov'T · Preparative biochemistry & biotechnology

Production of ligninolytic enzymes by solid-state fermentation using Pleurotus eryngii.

Pleurotus eryngii (DC.) Gillet (MCC58) was investigated for its ability to produce various ligninolytic enzymes such as laccase (Lac), manganese peroxidase (MnP), aryl alcohol oxidase (AAO), and lignin peroxidase (LiP) by solid-state fermentation (SSF), which was carried out using a support substrate from the fruit….

High relevance

Almond Mushroom · 2012 · Research Support, Non U.S. Gov'T · Experimental parasitology

Prophylactic or therapeutic administration of Agaricus blazei Murill is effective in treatment of murine visceral leishmaniasis.

The present study aimed to investigate the in vitro antileishmanial activity of five fractions obtained from Agaricus blazei water extract (AbM), namely, Fab1, Fab2, Fab3, Fab4, and Fab5; and use the selected leishmanicidal fraction to treat BALB/c mice infected with Leishmania chagasi..

Immune supportLiver support

High relevance

Almond Mushroom · 2012 · Research Support, Non U.S. Gov'T · PloS one

The anti-tumorigenic mushroom Agaricus blazei Murill enhances IL-1β production and activates the NLRP3 inflammasome in human macrophages.

Agaricus blazei Murill (AbM) has been reported to possess immune activity against tumors and infections through stimulation of mononuclear phagocytes. Recently, AbM extract was shown to induce the production of the pro-inflammatory cytokine, interleukin-1β (IL-1β), in human monocytes..

OncologyImmune supportEnergy & fatigue

High relevance

Niu-Chang-Chih · 2012 · Retracted Publication · Evidence-based complementary and alternative medicine: eCAM

The Antitumor Activity of Antrodia camphorata in Melanoma Cells: Modulation of Wnt/β-Catenin Signaling Pathways.

Antrodia camphorata (AC) is well known in Taiwan as a traditional Chinese medicine. The aim of this study was to investigate whether a fermented culture broth of AC could inhibit melanoma proliferation and progression via suppression of the Wnt/β-catenin signaling pathway..

Oncology

High relevance

Almond Mushroom · 2012 · Research Support, Non U.S. Gov'T · Parasitology research

Therapeutic efficacy induced by the oral administration of Agaricus blazei Murill against Leishmania amazonensis.

The development of therapeutic alternatives to treat leishmaniasis has received considerable attention. The present study aimed to investigate the efficacy of the Agaricus blazei Murill water extract (AbM) to treat BALB/c mice infected with Leishmania amazonensis.

Immune supportLiver support

High relevance

Niu-Chang-Chih · 2011 · Research Support, Non U.S. Gov'T · Sheng wu gong cheng xue bao = Chinese journal of biotechnology

[Medium optimization for mycelia production of Antrodia camphorata based on artificial neural network-genetic algorithm].

To illustrate the complex fermentation process of submerged culture of Antrodia camphorata ATCC 200183, we observed the morphology change of this filamentous fungus..

Metabolic health

High relevance

Yellow Morel · 2011 · English Abstract · Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials

[Optimization of culture conditions for production of extracellular polysaccharides by Morchella esculenta].

OBJECTIVE: To optimize the conditions for exopolysaccharides (EPS) production by Morchella esculenta GIM 5.69. METHODS: A Plackett-Burman design was used to evaluate the effects of variables factors..

Immune supportMetabolic health

High relevance

Turkey Tail · 2011 · Research Support, Non U.S. Gov'T · International journal of medicinal mushrooms

28-day oral safety evaluation of extracellular polysaccharopeptides produced in submerged culture from the turkey tail medicinal mushroom Trametes versicolor (L.:Fr.) Pilát LH-1 in mice.

Turkey tail medicinal mushroom, Trametes versicolor (TV), is a species with a variety of pharmacological activities. Its intracellular polysaccharopeptides are widely commercialized..

Immune supportRespiratory

High relevance

Almond Mushroom · 2011 · Research Support, Non U.S. Gov'T · In vivo (Athens, Greece)

Agaricus blazei Murill extract abrogates CCl4-induced liver injury in rats.

Agaricus blazei Murill (ABM) is enriched with polysaccharides, lipids, vitamins, fibers and minerals. Many studies have shown that ABM possesses immune-enhancing and anti-tumor effects.

OncologyImmune supportLiver support

High relevance

Chaga · 2011 · Research Support, Non U.S. Gov'T · Food & function

Amelioration of scopolamine induced cognitive dysfunction and oxidative stress by Inonotus obliquus - a medicinal mushroom.

The present study was aimed to investigate the cognitive enhancing and anti-oxidant activities of Inonotus obliquus (Chaga) against scopolamine-induced experimental amnesia. Methanolic extract of Chaga (MEC) at 50 and 100 mg kg (-1)doses were administered orally for 7 days to amnesic mice..

Cognition & nerves

High relevance

Chaga · 2011 · Research Support, Non U.S. Gov'T · Phytochemical analysis: PCA

Analysis of antioxidant metabolites by solvent extraction from sclerotia of Inonotus obliquus (Chaga).

INTRODUCTION: The sclerotia of Inonotus obliquus (Chaga) are effective therapeutic agents to treat several human malignant tumours and other diseases without unacceptable toxic side-effects. OBJECTIVE: To investigate solvent effects on metabolic profiles and antioxidant activities of extracts of Chaga..

OncologyImmune supportMetabolic health

High relevance

Niu-Chang-Chih · 2011 · Patent · journal metadata

ANTI-CANCER ACTIVE SUBSTANCE FROM ANTRODIA CAMPHORATA, METHOD FOR PREPARING THE SAME AND USE THEREOF

An anti-cancer active substance from Antrodia Camphorata, produced from mycelium of Antrodia Camphorata by following steps: (1) culturing mycelium of Antrodia Camphorata by liquid fermentation (2) extracting the thus-obtained mycelium with ethanol and concentrating the extracted solution to obtain an ethanol extract….

Oncology

High relevance

Maitake · 2011 · Research Support, Non U.S. Gov'T · Molecules (Basel, Switzerland)

Antioxidant properties and antioxidant compounds of various extracts from the edible basidiomycete Grifola frondosa (Maitake).

Grifola frondosa is an edible mushroom currently available in Taiwan. Ethanolic, cold-water and hot-water extracts were prepared and their antioxidant properties were investigated.

High relevance

King Oyster · 2011 · Research Support, Non U.S. Gov'T · Cellular and molecular biology (Noisy-le-Grand, France)

Biodegradation of brassica haulms by white rot fungus Pleurotus eryngii.

The white rot fungus P. eryngii was grown on chemically and hot water treated agrowaste Brassica haulms.

High relevance

Almond Mushroom · 2011 · Research Support, Non U.S. Gov'T · In vivo (Athens, Greece)

Carbon tetrachloride-induced hepatotoxicity and its amelioration by Agaricus blazei Murrill extract in a mouse model.

This study was conducted to evaluate the hepatoprotective effect of Agaricus blazei Murrill extract (ABM) against experimentally induced carbon tetrachloride (CCl(4)) toxicity in male BALB/c mice..

Liver support

High relevance

Mesima · 2011 · Patent · journal metadata

COMPOSITION FOR PREVENTING OR TREATING ATOPIC DERMATITIS AND ALLERGY-RELATED DISEASES COMPRISING FERMENTED PHELLINUS LINTEUS EXTRACT

PURPOSE: A composition containing fermented phellinus linteus extract is provided to effectively prevent or treat allergic dermatitis-associated disease. CONSTITUTION: A composition for preventing or treating allergic dermatitis-associated disease contains fermented phellinus linteus extract and pahrmacetuically….

Metabolic healthGut & microbiomeSkin & hydration

High relevance

Cordyceps · 2011 · Patent · journal metadata

CULTURING METHOD FOR CORDYCEPS MILITARIS

A culturing method for Cordyceps militaris includes puffing of a medium, then inoculating the medium with liquid inoculum of Cordyceps militaris. The method can reduce production period, decrease costs and improve the quality of product..

High relevance

Enoki · 2011 · Research Support, Non U.S. Gov'T · The Journal of biological chemistry

Endo-beta-1,3-galactanase from winter mushroom Flammulina velutipes.

Arabinogalactan proteins are proteoglycans found on the cell surface and in the cell walls of higher plants. The carbohydrate moieties of most arabinogalactan proteins are composed of β-1,3-galactan main chains and β-1,6-galactan side chains, to which other auxiliary sugars are attached..

High relevance

Chaga · 2011 · Research Support, Non U.S. Gov'T · Journal of industrial microbiology & biotechnology

Enhancement of exo-polysaccharide production and antioxidant activity in submerged cultures of Inonotus obliquus by lignocellulose decomposition.

We reported that lignocellulose decomposition can be used to facilitate the production of bioactive polysaccharides from submerged culture of Inonotus obliquus. Exo-polysaccharide (EPS) production and antioxidant activity by Inonotus obliquus was enhanced by employing lignocellulose decomposition in a corn….

Immune supportMetabolic health

High relevance

Maitake · 2011 · Research Support, Non U.S. Gov'T · Pharmaceutical biology

Enhancement of in vitro and in vivo anticancer activities of polysaccharide peptide from Grifola frondosa by chemical modifications.

CONTEXT: Grifola frondosa (Polyporaceae), maitake, is a widely consumed edible mushroom in some Asian countries. The fruit bodies and mycelia of maitake have shown different bioactive compounds with anticancer and other therapeutic properties..

OncologyImmune supportCognition & nerves

High relevance

King Oyster · 2011 · Research Support, Non U.S. Gov'T · Applied biochemistry and biotechnology

Expression and production of therapeutic recombinant human platelet-derived growth factor-BB in Pleurotus eryngii.

Recombinant human platelet-derived growth factor-BB (rhPDGF-BB) is widely used in many therapeutic applications. Until now, there has been no report on rhPDGF-BB expressed in fungi.

High relevance

Chaga · 2011 · Research Support, Non U.S. Gov'T · International journal of medicinal mushrooms

In vitro antitumor activity and structure characterization of ethanol extracts from wild and cultivated Chaga medicinal mushroom, Inonotus obliquus (Pers.:Fr.) Pilát (Aphyllophoromycetideae).

Inonotus obliquus (Pers.:Fr.) Pilát has been traditionally used as a folk remedy for treatment of cancers, cardiovascular disease and diabetes in Russia, Poland, and most of the Baltic countries, but natural reserves of this fungus have nearly been exhausted..

OncologyMetabolic health

High relevance

Shiitake · 2011 · Research Support, Non U.S. Gov'T · Journal of biomedicine & biotechnology

In vitro assessment of shiitake mushroom (Lentinula edodes) extract for its antigingivitis activity.

Gingivitis is a preventable disease characterised by inflammation of the gums due to the buildup of a microbial biofilm at the gingival margin. It is implicated as a precursor to periodontitis, a much more serious problem which includes associated bone loss..

Immune support

High relevance

King Oyster · 2011 · Research Support, Non U.S. Gov'T · Food and chemical toxicology: an international journal published for the British Industrial Biological Research Association

Inhibitory effect of Pleurotus eryngii extracts on the activities of allergic mediators in antigen-stimulated mast cells.

Pleurotus eryngii is an edible mushroom native to Europe, the Middle East, and North Africa, and is also grown in parts of Asia. The present study investigated the anti-allergy potential of P.

Immune support

High relevance

Chaga · 2011 · Research Support, Non U.S. Gov'T · Journal of ethnopharmacology

Inonotus obliquus extracts suppress antigen-specific IgE production through the modulation of Th1/Th2 cytokines in ovalbumin-sensitized mice.

ETHNOPHARMACOLOGICAL RELEVANCE: Chaga mushroom (Inonotus obliquus, IO) has been used as a folk remedy for cancer, digestive system diseases, and other illnesses in Russia and Eastern Europe. AIM OF THE STUDY: In the present study, we investigated the immunomodulating effects of IO through in vivo and ex vivo studies..

OncologyImmune supportGut & microbiome

High relevance

King Oyster · 2011 · Research Support, Non U.S. Gov'T · Biological trace element research

Interaction of trace elements and ligninolytic enzymes in Pleurotus eryngii.

Considering the fact that some trace elements have influence on the growth and physiological processes in the fungi, the aim of this study was to resolve the question of whether Fe, Zn, and Se, added to the medium in the different forms, affect activity of selected Pleurotus eryngii ligninolytic enzymes participating….

High relevance

Yellow Morel · 2011 · Comparative Study · Journal of the science of food and agriculture

Isolation, partial characterisation and immunomodulatory activities of polysaccharide from Morchella esculenta.

BACKGROUND: Polysaccharides extracted from fungi or algae have shown a variety of medical activities, and the exploitation of polysaccharides for application in pharmacy has been very promising..

Immune supportEnergy & fatigue

High relevance

Lion's Mane · 2011 · Research Support, Non U.S. Gov'T · Food & function

Mechanism of Hericium erinaceus (Yamabushitake) mushroom-induced apoptosis of U937 human monocytic leukemia cells.

Phytochemicals in some foods are a potential source of bioactive safe compounds for cancer chemoprevention and suppression of tumor initiation, promotion, and metastasis..

OncologyEnergy & fatigue

High relevance

Maitake · 2011 · Research Support, Non U.S. Gov'T · International journal of medicinal mushrooms

Nonvolatile taste components of culinary-medicinal maitake mushroom, Grifola frondosa (Dicks.:Fr.) S.F. Gray.

Culinary-medicinal maitake mushroom Grifola frondosa (Dicks.: Fr.) S.F. Gray mycelium was inoculated into wheat, a new product was formed after fungal fermentation, and its nonvolatile taste components were studied..

High relevance

Almond Mushroom · 2011 · Research Support, Non U.S. Gov'T · In vivo (Athens, Greece)

Possible reduction of hepatoma formation by Smmu 7721 cells in SCID mice and metastasis formation by B16F10 melanoma cells in C57BL/6 mice by Agaricus blazei murill extract.

Agaricus blazei Murill extract (ABM) has been reported to possess antitumor effects. In this study, the role of ABM in tumor growth and metastasis in vivo was evaluated in experimental Smmu 7721 hepatoma cells in severe combined immunodeficiency (SCID) mice and B16F10 melanoma cells lung metastasis in C57BL/6 mice..

OncologyImmune supportLiver supportRespiratory

High relevance

Lion's Mane · 2011 · Research Support, Non U.S. Gov'T · International journal of medicinal mushrooms

Potential activity of aqueous extract of culinary-medicinal Lion's Mane mushroom, Hericium erinaceus (Bull.: Fr.) Pers. (Aphyllophoromycetideae) in accelerating wound healing in rats.

This study was conducted to evaluate the effects of topical application of aqueous extract of Hericium erinaceus fruiting bodies (HEFB) on the rate of wound healing enclosure and histology of the healed wound. Five groups of male Sprague-Dawley rats were experimentally wounded in the posterior neck area..

Immune supportSkin & hydration

High relevance

Maitake · 2011 · Research Support, Non U.S. Gov'T · International journal of medicinal mushrooms

Preparation of culinary-medicinal maitake mushroom, Grifola frondosa (Dicks.: Fr.) S.F. Gray (Aphyllophoromycetideae)-fermented wheat and its antioxidant properties.

The optimization of solid-state fermentation conditions for mycelial growth in wheat by culinary-medicinal maitake mushroom, Grifola frondosa (Dicks.: Fr.) S.F. Gray was studied..

High relevance

Chaga · 2011 · Research Support, Non U.S. Gov'T · Phytochemical analysis: PCA

Rapid isolation and purification of inotodiol and trametenolic acid from Inonotus obliquus by high-speed counter-current chromatography with evaporative light scatting detection.

INTRODUCTION: In Eastern Europe, especially Russia, the fruiting body of Inonotus obliquus has been used as a folk medicine for cancer since the sixteenth or seventeenth century. Inotodiol and trametenolic acid are considered to be the main bioactive compounds of the fruiting body of the mushroom..

OncologyEnergy & fatigueMetabolic healthRespiratory

High relevance

Zhu Ling · 2011 · Research Support, Non U.S. Gov'T · Journal of ethnopharmacology

TLR4-mediated activation of macrophages by the polysaccharide fraction from Polyporus umbellatus(pers.) Fries.

AIM OF THE STUDY: Zhu Ling (Polyporus umbellatus) is well-known to reduce the risk of a variety of diseases. In this study, we explored the molecular mechanism of its immunostimulatory potency in immune responses of macrophages, using polysaccharides prepared from Polyporus umbellatus (PPS)..

Immune support

High relevance

Niu-Chang-Chih · 2011 · Patent · journal metadata

USE OF ANTRODIA CAMPHORATA FOR TREATING DISEASES

The present invention relates to the use of antrodia camphorata in the treatment of skin conditions, allergic rhinitis, diabetes mellitus and its complications, cancer cachexia, hypercholesterolemia, gout in a subject in need of such treatment..

OncologyMetabolic healthSkin & hydration

High relevance

Nameko · 2010 · Research Support, Non U.S. Gov'T · Eukaryotic cell

A-mating-type gene expression can drive clamp formation in the bipolar mushroom Pholiota microspora (Pholiota nameko).

In the bipolar basidiomycete Pholiota microspora, a pair of homeodomain protein genes located at the A-mating-type locus regulates mating compatibility. In the present study, we used a DNA-mediated transformation system in P.

High relevance

Mesima · 2010 · Patent · journal metadata

ANTICANCER HEALTH FOOD CONTAINING PHELLINUS LINTEUS AND VEGETABLE WORMS

The present invention relates to a health food containing extracts of Phellinus linteus and vegetable worms for preventing and relieving cancer. The health food contains ethanol extract of the mixture containing the mycelia of the Phellinus linteus and vegetable worms at a ratio of 1:5 to 5:1..

OncologyImmune support

High relevance

Niu-Chang-Chih · 2010 · Research Support, Non U.S. Gov'T · Journal of ethnopharmacology

Apoptotic effects of a high performance liquid chromatography (HPLC) fraction of Antrodia camphorata mycelia are mediated by down-regulation of the expressions of four tumor-related genes in human non-small cell lung carcinoma A549 cell.

AIM OF THE STUDY: Antrodia camphorata (niu-chang-chih) is a fungus native to Taiwan which is believed to be effective in preventing diseases. Recent reports demonstrate that Antrodia camphorata products induce the apoptosis of various kinds of tumor cells..

OncologyImmune supportEnergy & fatigueRespiratory

High relevance

Shiitake · 2010 · Research Support, Non U.S. Gov'T · Journal of medicinal food

Bioavailability of iron from cereal products enriched with dried shittake mushrooms (Lentinula edodes) as determined by iron regeneration efficacy method in female rats.

Lentinula edodes shiitake mushrooms are rich sources of iron, which in addition to their relatively high nutritive value are also characterized by high contents of biologically active components..

Liver support

High relevance

King Oyster · 2010 · Research Support, Non U.S. Gov'T · Bioresource technology

Biochemical and enzymatic properties of a fibrinolytic enzyme from Pleurotus eryngii cultivated under solid-state conditions using corn cob.

Biochemical and enzymatic properties of a fibrinolytic enzyme purified from Pleurotus eryngii cultivated under solid-state conditions using corn cob as energy source were investigated. The molecular mass of the enzyme was estimated to be 14 kDa by SDS-PAGE..

Energy & fatigue

High relevance

Turkey Tail · 2010 · Research Support, Non U.S. Gov'T · Biodegradation

Cresols utilization by Trametes versicolor and substrate interactions in the mixture with phenol.

The ability of the white rot fungus Trametes versicolor strain 1 to degrade and utilize methylated phenols (cresols) was established for the first time in a medium not containing any other carbon components..

Energy & fatigue

High relevance

King Oyster · 2010 · Patent · journal metadata

Culture medium for pleurotus eryngii and cultivation method of pleurotus eryngii

The invention relates to a culture medium for pleurotus eryngii and a cultivation method of the pleurotus eryngii. The culture medium comprises the following components according to the formula: 75 to 80 percent of solidago canadensis which is cut to have a particle diameter of 0.8 to 1.2cm, 17 to 22 percent of bran,….

High relevance

Niu-Chang-Chih · 2010 · Patent · journal metadata

CYCLOHEXENONE COMPOUNDS FROM ANTRODIA CAMPHORATA AND PHARMACEUTICAL COMPOSITIONS THEREOF USEFUL FOR TREATING AUTOIMMUNE DISEASES

The present invention relates to a compound of Antrodia camphorata used to treat autoimmune diseases, in particular to an extract, 4-hydroxy-2,3-dimethoxy-6-methyl-5(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-cyclohex-2-enone, isolated from Antrodia camphorata, and its use in alleviating symptoms of autoimmune diseases….

Immune support

High relevance

Zhu Ling · 2010 · Research Support, Non U.S. Gov'T · Journal of ethnopharmacology

Diuretic activity and kidney medulla AQP1, AQP2, AQP3, V2R expression of the aqueous extract of sclerotia of Polyporus umbellatus FRIES in normal rats.

AIM OF THE STUDY: Zhuling, sclerotia of Polyporus umbellatus FRIES, a Traditional Chinese Medicine, has long been used as a diuretic. The aim of the present study was to evaluate the diuretic effect on the urinary electrolyte concentration (Na(+), K(+), and Cl(-)) and regulation of the relative mRNA expression of….

High relevance

Turkey Tail · 2010 · Research Support, Non U.S. Gov'T · Water science and technology: a journal of the International Association on Water Pollution Research

Effect of glucose on enzyme activity and color removal by Trametes versicolor for high strength landfill leachate.

This research was carried out to study the treatment of landfill leachate by immobilized Trametes versicolor BCC 8725. Leachate was collected from Nonthaburi disposal site of Thailand from a pipe as discharged from landfill to the stabilization pond..

Energy & fatigueMetabolic health

High relevance

Chaga · 2010 · Comparative Study · Journal of food science

Effects of ultrasonic treatment on the physicochemical properties and DPPH radical scavenging activity of polysaccharides from mushroom Inonotus obliquus.

UNLABELLED: An ultrasonic technique was employed to extract polysaccharides from Inonotus obliquus (UPS). The effects of ultrasonic conditions on the recovery and 1, 1-diphenyl -2-picrylhydrazyl (DPPH) radical scavenging activity of UPS were evaluated..

OncologyImmune supportMetabolic health

High relevance

Enoki · 2010 · Research Support, Non U.S. Gov'T · Microbiological research

Electrophoretic karyotyping and construction of a bacterial artificial chromosome library of the winter mushroom Flammulina velutipes.

An electrophoretic karyotype of Korean Flammulina velutipes was obtained using contour-clamped homogeneous electric field (CHEF) gel electrophoresis. The monokaryotic progenies (4019-20 and 4019-18) and a dikaryotic strain (4019-2018) had 6-8 chromosomes, with sizes ranging from 1.6 to 5.8 megabase (Mb) pairs..