MycoData

Cordyceps · 2023 · Preprint · journal metadata

Ophiocordyceps megala sp. nov (Ophiocordycepitaceae) enriches the species diversity of the O. sinensis-affined lineage

Abstract Ophiocordyceps is a species-rich genus in the order Hypocreales (Ascomycota) including large numbers of invertebrate-pathogen. Ophiocordyceps sinensis is a famous traditional Chinese medicine that adapts to the alpine environment in the Qinghai-Tibet Plateau and adjacent region..

Reishi · 2023 · Preprint · journal metadata

Performance of cocultivation of Chlorella vulgaris and four different fungi in biogas slurry purification and biogas upgrading by induction of strigolactone (GR24) and endophytic bacteria

This study aimed to determine the best fungi to form the algal-bacterial-fungi symbiotic system and identify the optimal conditions for the synchronous processing of biogas slurry and biogas. Chlorella vulgaris ( C..

Cognition & nervesEnergy & fatigue

Almond Mushroom · 2023 · Randomized Controlled Trial · Scientific reports

Reduction in sugar drink valuation and consumption with gamified executive control training.

The overvaluation of high-energy, palatable food cues contributes to unhealthy eating and being overweight. Reducing the valuation of unhealthy food may thus constitute a powerful lever to improve eating habits and conditions characterized by unhealthy eating..

Almond Mushroom · 2023 · Randomized Controlled Trial · Cancer

Single-photon emission computed tomography-defined active bone marrow-sparing volumetric-modulated arc therapy reduces the incidence of acute hematologic toxicity in locally advanced cervical cancer patients who receive chemoradiotherapy: A single-center prospective randomized controlled trial.

BACKGROUND: This study aims to test the efficacy of single-photon emission computed tomography (SPECT)-defined active bone marrow-sparing (ABMS) volumetric-modulated arc therapy (VMAT) in reducing grade 3+ acute hematologic toxicity (HT) in locally advanced cervical cancer patients treated with chemoradiotherapy..

OncologyLiver support

King Oyster · 2022 · Review · Bioresources and bioprocessing

Biodegradation of plastic polymers by fungi: a brief review.

Plastic polymers are non-degradable solid wastes that have become a great threat to the whole world and degradation of these plastics would take a few decades. Compared with other degradation processes, the biodegradation process is the most effective and best way for plastic degradation due to its non-polluting….

Shiitake · 2022 · Clinical Trial Protocol · Trials

Efficacy of active hexose correlated compound on survival of patients with resectable/borderline resectable pancreatic cancer: a study protocol for a double-blind randomized phase II study.

BACKGROUND: The prognosis of pancreatic ductal adenocarcinoma remains very poor. One possible reason for the short survival of patients with this disease is malnutrition, which can be present at the initial diagnosis, and continue after pancreatectomy..

Oncology

Oyster Mushroom · 2022 · Review · Microorganisms

Mycelium vs. Fruiting Bodies of Edible Fungi-A Comparison of Metabolites.

Edible mushrooms are widely appreciated for their appealing flavours, low caloric values and high content of presumably health-protecting metabolites. Their long history of safe use together with the looming worldwide food crisis have revived the idea of generating meat analogues and protein isolates by the controlled….

Cognition & nervesEnergy & fatigueRespiratory

Agarikon · 2022 · Review · Environmental chemistry letters

Old growth forests and large old trees as critical organisms connecting ecosystems and human health. A review.

Old forests containing ancient trees are essential ecosystems for life on earth. Mechanisms that happen both deep in the root systems and in the highest canopies ensure the viability of our planet..

Immune supportGut & microbiomeRespiratory

Shiitake · 2021 · Randomized Controlled Trial · Nutrients

Adjuvant Effect of Orally Applied Preparations Containing Non-Digestible Polysaccharides on Influenza Vaccination in Healthy Seniors: A Double-Blind, Randomised, Controlled Pilot Trial.

Senior individuals can suffer from immunosenescence and novel strategies to bolster the immune response could contribute to healthy ageing. In this double-blind, randomised, controlled pilot trial, we investigated the ability of non-digestible polysaccharide (NPS) preparations to enhance the immune response in a human….

Cognition & nervesMetabolic health

Lion's Mane · 2021 · Review · Bioscience, biotechnology, and biochemistry

Chemical studies on bioactive compounds related to higher fungi.

Hericium erinaceus (Yamabushitake in Japan) is a well-known edible and medicinal mushroom. We discovered antidementia compounds, hericenones C to H, from the fruiting bodies and erinacine A to I from the cultured mycelia of the fungus..

OncologyImmune supportCognition & nerves

Cordyceps · 2021 · Review · Food & function

Dietary agents in mitigating chemotherapy-related cognitive impairment (chemobrain or chemofog): first review addressing the benefits, gaps, challenges and ways forward.

Chemobrain or chemofog is one of the important but less investigated side effects, where the cancer survivors treated with chemotherapy develop long-term cognitive impairments, affecting their quality of life. The biological mechanisms triggering the development of chemobrain are largely unknown..

Turkey Tail · 2021 · Preprint · journal metadata

Melanin Production and Laccase Mediated Oxidative Stress Alleviation During Fungal-fungal Interaction Among Basidiomycetes Fungi

Abstract Fungal-fungal interaction often leads to the change in metabolite profile of both the interacting fungus which may have potential implication in industry or agriculture..

Skin & hydration

OncologyImmune supportLiver supportSkin & hydration

Chaga · 2020 · Journal Article · Voprosy virusologii

[Antiviral activity of extracts of basidiomycetes and humic compounds substances against Human Immunodeficiency Virus (Retroviridae: Orthoretrovirinae: Lentivirus: Human immunodeficiency virus 1) and Herpes Simplex Virus (Herpesviridae: Simplexvirus: Human alphaherpesvirus 1)].

INTRODUCTION: One of the most urgent problem of modern medicine is the fight against the disease caused by the Human Immunodeficiency Virus (HIV) - HIV infection..

Chaga · 2019 · Journal Article · Phytomedicine: international journal of phytotherapy and phytopharmacology

Inotodiol inhibits cells migration and invasion and induces apoptosis via p53-dependent pathway in HeLa cells.

BACKGROUND: Inonotus obliquus, namely as Chaga mushroom, is a medicinal and edible fungus, which is widely used in food and medical fields. Inotodiol, a natural lanostane-type triterpenoid with remarkable pharmacological activities, was isolated from Inonotus obliquus, which its potential anti-tumor molecular….

OncologySkin & hydration

King Oyster · 2004 · Journal Article · Food chemistry

Commercial mushrooms: nutritional quality and effect of cooking

With the aim of extending knowledge on chemical composition of mushrooms, commercial samples, widely consumed in Italy (Boletus group, Agrocybe aegerita and Pleurotus eryngii) have been examined to determine proximate composition and some components of nutritional interest such as dietary fibre, chitin, beta glucan….

Gut & microbiomeSkin & hydration

Snow Fungus · 1993 · Review · Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]

[Pseudomonas contamination of Chinese herbal drug. Tremella fuciformis].

Metadata-grounded summary: This review indexes research on Tremella fuciformis in Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] in 1993. MycoData maps the paper to gut & microbiome, skin & hydration based on its title, species context, article metadata, and study classification..

Almond Mushroom · 2026 · Preprint · journal metadata

Cellfoundry: a GPU-accelerated, multi-physics ABM framework for cellular microenvironment and organoid-scale studies

ABSTRACT Advanced in vitro systems such as organoids and microfluidic organ-on-a-chip platforms enable physiologically richer experimentation, but their complexity creates large parameter spaces and makes it difficult to disentangle the mechanistic roles of transport, mechanics, and extracellular microstructure..

OncologyImmune supportCognition & nervesEnergy & fatigue

Cordyceps · 2026 · Preprint · journal metadata

Fungal Cordyceps Nucleosides and Analogs as Potential PD-L1 Inhibitors as Anti-Glioblastoma: An In Silico Multiparameter Optimization (MPO) Design

Immune checkpoint modulation has emerged as a promising strategy in cancer therapy, including the treatment of aggressive tumors such as glioblastoma. Among these targets, programmed death-ligand 1 (PD-L1) plays a key role in tumor immune evasion and represents an attractive target for small-molecule inhibitor….

Cognition & nervesEnergy & fatigue

Reishi · 2026 · Systematic Review · The international journal of neuropsychopharmacology

The efficacy of nutritional phytochemical compounds in improving cognition.

The incidence of cognitive disorders is rising, and medications to address cognitive impairments are limited. Phytochemical compounds have had some success in improving cognitive outcomes in preclinical studies..

Almond Mushroom · 2025 · Systematic Review · Frontiers in psychology

Bridging behavioral theory and household energy decisions: enhancing agent-based models with behavioral analysis.

Households are crucial in the energy transition, accounting for over 25% of the European Union's energy consumption. To design effective policy measures that motivate households to change their behavior in favor of the energy transition, agent-based models (ABMs) are vital..

Oyster Mushroom · 2025 · Preprint · journal metadata

Complete genome sequences of tolaasin-detoxifying Mycetocola species isolated from oyster mushroom

Complete genome sequences of tolaasins-detoxifying Mycetocola spp., M. lacteus MAFF 211326, M.

Almond Mushroom · 2025 · Systematic Review · The Journal of bone and joint surgery. American volume

Efficacy and Safety of Osteobiologics for Lumbar Spinal Fusion: A Systematic Review and Network Meta-Analysis.

BACKGROUND: Lumbar spinal fusion (LSF) is a common surgical procedure for treating lumbar degenerative conditions. The use of osteobiologics to enhance fusion has emerged as a promising alternative to address the limitations of autologous iliac crest bone graft (AICBG), but their comparative efficacy and safety remain….

Cordyceps · 2025 · Systematic Review · Pathogens (Basel, Switzerland)

Fungi-Based Bioproducts: A Review in the Context of One Health.

Entomopathogenic fungus-based biopesticides are an excellent alternative to synthetic pesticides and are widely used in insect pest control. With the transformations of the agri-food system, it is important to consider the One Health approach, which recognizes that health threats are shared at the interface between….

Energy & fatigueMetabolic healthGut & microbiome

Turkey Tail · 2025 · Research Support, Non U.S. Gov'T · Applied and environmental microbiology

Fungus-mediated bacterial survival and migration enhance wood lignin degradation.

UNLABELLED: Bacterial-fungal interactions are increasingly recognized as a key factor in wood decomposition; however, the specific mechanisms underlying these interactions remain unclear..

Almond Mushroom · 2025 · Preprint · journal metadata

Multiscale Modeling of Tumor Angiogenesis and Resistance Evolution: A Hybrid PDE–ABM Framework for Cancer Prediction and Therapy Planning

Tumor drug resistance involves intrinsic cellular mechanisms, microenvironmental regulation, and epigenetic alterations. Hypoxia, drug distribution, and microvascular heterogeneity critically mediate resistance within the tumor microenvironment (TME)..

OncologyEnergy & fatigue

Chaga · 2024 · Preprint · journal metadata

(RAP)ENSANDO A RAÇA E O RACISMO: A FERIDA, A CHAGA, A PROCURA DA CURA DE UM VERDADEIRO DRAMA

Neste trabalho, apresento algumas partes da minha dissertação defendida em 2023, onde analiso depoimentos produzidos e compartilhados durante as dinâmicas efetivadas no campo de pesquisa..

Turkey Tail · 2024 · Comparative Study · Viruses

Comparative Analysis of Viromes Identified in Multiple Macrofungi.

Macrofungi play important roles in the soil elemental cycle of terrestrial ecosystems. Fungal viruses are common in filamentous fungi, and some of them can affect the growth and development of hosts.

Respiratory

Almond Mushroom · 2024 · Systematic Review · Cell and tissue banking

Efficacy of mesenchymal stromal cells in the treatment of type 1 diabetes: a systematic review.

To investigate the efficacy of mesenchymal stromal cells in the treatment of type 1 diabetes. Articles about the effects of mesenchymal stromal cells for T1D were retrieved in PubMed, Web of Science, Embase, and the Cochrane Library databases up to July 2023..

Metabolic health

Almond Mushroom · 2024 · Preprint · journal metadata

Simulation of knowledge transfer in complex networks by coupling ABM and GIS: a local road freight transport system as a case study

Abstract Some complex social networks are driven by adaptive and co-evolutionary patterns. However, these can be difficult to detect and analyse since the links between actors are circumstantial and often not revealed..

Energy & fatigueRespiratory

Cordyceps · 2024 · Meta-Analysis · Pharmaceutical biology

Therapeutic efficacy and pharmacological mechanism of Bailing capsule on chronic obstructive pulmonary disease: a meta-analysis and network pharmacology.

CONTEXT: Bailing capsule, derived from Cordyceps sinensis (Berk.) Sacc. (Clavicipitaceae), has shown potential in the treatment of chronic obstructive pulmonary disease (COPD), a prevalent respiratory disorder..

Reishi · 2023 · Journal Article · International journal of biological macromolecules

A new strategy to improve Ganoderma polysaccharides production by symbiotic fungi elicitors through activating the biosynthetic pathway.

Ganoderma lucidum polysaccharides (GLP) attract growing attention due to their remarkable bioactivities, but the low content in raw materials remains a bottleneck severely restricting their application..

Turkey Tail · 2023 · Research Article · RSC advances

Eco-friendly TEMPO/laccase/O2 biocatalytic system for degradation of Indigo Carmine: operative conditions and laccase inactivation.

The biocatalytic system laccase/TEMPO/O2 has attracted the attention of researchers over the past two decades. A variety of applications for the system include organic synthesis, modification of cellulose, and oxidative degradation of environmental contaminants..

OncologyImmune supportRespiratory

Reishi · 2023 · Journal Article · Prilozi (Makedonska akademija na naukite i umetnostite. Oddelenie za medicinski nauki)

Effect of Supplemental Antioxidant-Based Therapy on the Oxidative Stress Level in COVID-19 Patients.

Background: COVID-19 is a disease in several stages starting with virus replication to dysregulation in immune system response, organ failure and recovery/death. Our aim was to determine the effect of Ganoderma lucidum, lycopene, sulforaphane, royal jelly and resveratrol extract on markers of oxidative stress,….

OncologyCognition & nervesLiver support

Reishi · 2023 · Research Article · Aging medicine (Milton (N.S.W))

Ganoderic Acid A targeting leucine-rich repeat kinase 2 involved in Parkinson's disease-A computational study.

OBJECTIVE: This study aims to find the most promising Ganoderma lucidium targeting LRRK2 involved in PD. METHODS: First ADMET analysis was performed for five compounds followed by molecular docking of each compound..

Immune supportMetabolic health

Reishi · 2023 · Journal Article · Theranostics

GLSP and GLSP-derived triterpenes attenuate atherosclerosis and aortic calcification by stimulating ABCA1/G1-mediated macrophage cholesterol efflux and inactivating RUNX2-mediated VSMC osteogenesis.

Background and Purpose: Atherosclerosis is the main pathophysiological foundation of cardiovascular disease, which was caused by inflammation and lipid metabolism disorder, along with vascular calcification..

Oyster Mushroom · 2023 · Research Article · Polymers

Harvesting Mycelial Biomass of Selected Basidiomycetes for Chitosan Biopolymer Extraction.

This study investigates the mycelial biomass production and chitosan extraction potential of various Basidiomycota strains, including Heterobasidion annosum, Phanerochaete chrysosporium, Pleurotus ostreatus, Trametes versicolor, and Lentinus lepideus..

Oyster Mushroom · 2023 · Research Article · Frontiers in nutrition

Is mushroom polysaccharide extract a better fat replacer than dried mushroom powder for food applications?

INTRODUCTION: β-glucans found in the cell walls of mushrooms can be a beneficial food additive in replacing fat in commercial food products. METHODS: Four commonly consumed mushroom species in Singapore, i.e., Pleurotus ostreatus spp., Lentinus edodes, Agaricus bisporus, and Flammulina velutipes were profiled for the….

Chaga · 2023 · Research Article · Molecules (Basel, Switzerland)

Microwave Heating for Synthesis of Carbonaceous Adsorbents for Removal of Toxic Organic and Inorganic Contaminants.

The residues obtained from the extraction of Inonotus obliquus fungus were used to produce carbonaceous adsorbents. The initial material was subjected to pyrolysis in a microwave oven..

Turkey Tail · 2023 · Research Article · Microorganisms

Optimization of Fermentation Conditions and Product Identification of a Saponin-Producing Endophytic Fungus.

BACKGROUND: Some fungal endophytes isolated from P. ginseng may present a new method of obtaining saponins.

Metabolic health

Reishi · 2023 · Journal Article · Water environment research: a research publication of the Water Environment Federation

Performance of cocultivation of Chlorella vulgaris and four different fungi in biogas slurry purification and biogas upgrading by induction of strigolactone (GR24) and endophytic bacteria.

This study aimed to determine the best fungi to form the algal-bacterial-fungal symbionts and identify the optimal conditions for the synchronous processing of biogas slurry and biogas. Chlorella vulgaris (C..

Chaga · 2023 · Journal Article · Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy

Studies on the interaction mechanism between xanthine oxidase and osmundacetone: Molecular docking, multi-spectroscopy and dynamical simulation.

Xanthine oxidase (XO) is a key enzyme in uric acid production, and its molybdopterin (Mo-Pt) domain is an important catalytic center when xanthine and hypoxanthine are oxidated. It is found that the extract of Inonotus obliquus has an inhibitory effect on XO..

Turkey Tail · 2023 · Research Article · Toxins

The Effect of Mushroom Culture Filtrates on the Inhibition of Mycotoxins Produced by Aspergillus flavus and Aspergillus carbonarius.

Two of the mycotoxins of greatest agroeconomic significance are aflatoxin B1 (AFB1), and ochratoxin A (OTA). It has been reported that extracts from some wood-decaying mushrooms, such as Lentinula edodes and Trametes versicolor showed the ability to inhibit AFB1 or OTA biosynthesis..

Shiitake · 2023 · Research Article · Foods (Basel, Switzerland)

Transglutaminase-Catalyzed Glycosylation Improved Physicochemical and Functional Properties of Lentinus edodes Protein Fraction.

Lentinula edodes has high nutritional value and abundant protein. In order to develop and utilize edible mushroom protein, this study was designed to investigate the effects of TGase-catalyzed glycosylation and cross-linking on the physicochemical and functional properties of Lentinus edodes protein fraction..

Energy & fatigueLiver supportSkin & hydration

Lion's Mane · 2022 · Journal Article · International journal of biological macromolecules

A self-healing hydrogel based on oxidized microcrystalline cellulose and carboxymethyl chitosan as wound dressing material.

As the food processing by-products, hericium erinaceus residues (HER) and pineapple peel (PP) are good sources of cellulose and chitosan that can be prepared into hydrogels for structuring a drug delivery system..

Oyster Mushroom · 2022 · Journal Article · Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment

Accumulation of HT-2 toxin from contaminated mushroom compost by edible Agaricus bisporus.

Wheat straw is commonly used as a cellulose source in mushroom compost and could be a secondary source of mycotoxin contamination in the food chain. We cultivated edible Agaricus bisporus and Pleurotus ostreatus on T-2/HT-2 artificially-contaminated mushroom compost and developed and in-house validated an UHPLC-MS/MS….

Turkey Tail · 2022 · Journal Article · Bioresource technology

Biodegradation of cyclophosphamide and etoposide by white rot fungi and their degradation kinetics.

The biodegradation of cyclophosphamide and etoposide by Trametes versicolor (AH05), Ganoderma lucidum (MTCC-1039), and Phanerochaete chrysosporium (MTCC-787) were tested for 3, 6, 9, 12, and 15 days, respectively. G..

Reishi · 2022 · Journal Article · Sensors (Basel, Switzerland)

Effect of Pd-Sensitization on Poisonous Chlorine Gas Detection Ability of TiO2: Green Synthesis and Low-Temperature Operation.

Ganoderma lucidum mushroom-mediated green synthesis of nanocrystalline titanium dioxide (TiO2) is explored via a low-temperature (≤70 °C) wet chemical method. The role of Ganoderma lucidum mushroom extract in the reaction is to release the ganoderic acid molecules that tend to bind to the Ti4+ metal ions to form a….

Turkey Tail · 2022 · Research Article · Polymers

Effect of Tannin Furanic Polymer in Comparison to Its Mimosa Tannin Extract on the Growth of Bacteria and White-Rot Fungi.

Tannins are well-known to protect plants from bacteria and fungi, but nothing is known about its effects on microorganisms once they are copolymerized. Therefore, a study was conducted to evaluate the effect of a tannin−furanic polymer in comparison with industrial mimosa tannin extract on the in vitro growth of two….

Metabolic health