MycoData

Phellinus linteus (mushroom) grown on Rosa multiflora (PL@RM), exposed beneficial effect and safety on Type 2 diabetes mellitus (T2DM) from Korean folk remedies. However, its active chemical constituents and mechanism(s) against T2DM have not been confirmed..

Energy & fatigueMetabolic health

High relevance

Turkey Tail · 2021 · Journal Article · Food and Bioproducts Processing

Activity enhancement of Trametes versicolor aflatoxin B1-degrading enzyme (TV-AFB1D) by molecular docking and site-directed mutagenesis techniques

Aflatoxin B₁ (AFB₁) is highly carcinogenic and teratogenic as a secondary metabolite of Aspergillus flavus and Aspergillus parasiticus. Trametes versicolor aflatoxin B₁-degrading enzyme (TV-AFB₁D) has capability of AFB₁ degradation..

Energy & fatigue

High relevance

Reishi · 2021 · Research Article · ACS omega

Advancement of Microwave-Assisted Biosynthesis for Preparing Au Nanoparticles Using Ganoderma lucidum Extract and Evaluation of Their Catalytic Reduction of 4-Nitrophenol.

This study describes the biosynthesis of gold nanoparticles (AuNPs) using the extract of Ganoderma lucidum in the buffer zone of Bach Ma National Park, Vietnam, as a reducing and protecting agent using microwave-assisted synthesis..

Energy & fatigue

High relevance

Oyster Mushroom · 2021 · Journal Article · Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire

Alternating current electric field inhibits browning of Pleurotus ostreatus via inactivation of oxidative enzymes during postharvest storage

Oyster mushrooms (Pleurotus ostreatus, P. ostreatus) are rich in nutrients and have a pleasant flavour.

Energy & fatigue

High relevance

Oyster Mushroom · 2021 · Journal Article · Microbial cell factories

Alternative oxidase gene induced by nitric oxide is involved in the regulation of ROS and enhances the resistance of Pleurotus ostreatus to heat stress.

BACKGROUND: In China, during the cultivation process of Pleurotus ostreatus, the yield and quality of fruiting bodies are easily affected by high temperatures in summer..

Energy & fatigue

High relevance

Niu-Chang-Chih · 2021 · Journal Article · Journal of separation science

An efficient high-speed countercurrent chromatography method for preparative isolation of highly potent anti-cancer compound antroquinonol from Antrodia camphorata after experimental design optimized extraction.

To avoid irreversible stationary phase adsorption and tedious and time-consuming separation steps, high-speed countercurrent chromatography was employed for the preparative separation of anti-tumor compound antroquinonol from solid fermentation culture of Antrodia camphorata for the first time..

OncologyEnergy & fatigue

High relevance

Zhu Ling · 2021 · Research Article · Frontiers in microbiology

Armillaria mellea Symbiosis Drives Metabolomic and Transcriptomic Changes in Polyporus umbellatus Sclerotia.

Sclerotia, the medicinal part of Polyporus umbellatus, play important roles in diuresis and renal protection, with steroids and polysaccharides as the main active ingredients. The sclerotia grow and develop only after symbiosis with Armillaria sp..

Immune supportEnergy & fatigueMetabolic health

High relevance

Snow Fungus · 2021 · Journal Article · International Journal of Biological Macromolecules

Characterization of chitin-glucan complex from Tremella fuciformis fermentation residue and evaluation of its antibacterial performance

Submerged fermentation of fungi is an efficient way to obtain extracellular polysaccharides, however, in this process, excess discarded biomass is produced. In this study, Tremella fuciformis mycelia were reused as the raw material to isolate a novel fungal chitin-glucan complex (CGC-TFM) using alkaline extraction..

Immune supportEnergy & fatigueMetabolic health

High relevance

Snow Fungus · 2021 · Journal Article · International journal of biological macromolecules

Characterization of chitin-glucan complex from Tremella fuciformis fermentation residue and evaluation of its antibacterial performance.

Immune supportEnergy & fatigueMetabolic health

High relevance

Enoki · 2021 · Journal Article · Food and chemical toxicology: an international journal published for the British Industrial Biological Research Association

Characterization of soy protein isolate/Flammulina velutipes polysaccharide hydrogel and its immunostimulatory effects on RAW264.7 cells.

Soy protein isolate (SPI) is a nutritional commercial product, while the poor solubility and gelling restricts its applications for functional foods. To surmount the challenge presented by this poor solubility, the gelling polysaccharide shows potential in ameliorating SPI..

OncologyImmune supportEnergy & fatigueMetabolic health

High relevance

Lion's Mane · 2021 · Journal Article · Carbohydrate polymers

Construction of hydrogels based on the homogeneous carboxymethylated chitin from Hericium erinaceus residue: Role of carboxymethylation degree.

Carboxymethyl chitin hydrogels with different degree of substitution (DS) were prepared by the homogeneous carboxymethylation of chitin extracted from Hericium erinaceus residue. The effect of DS on gel structure and property were studied..

Energy & fatigue

High relevance

Turkey Tail · 2021 · Research Article · Saudi journal of biological sciences

Deciphering the CNS anti-depressant, antioxidant and cytotoxic profiling of methanol and aqueous extracts of Trametes versicolor and molecular interactions of its phenolic compounds.

The present study sought to evaluate the central nervous system (CNS) depressant, antioxidant, and cytotoxicity activity of methanol and aqueous extract of Trametes versicolor (METV and AETV)..

OncologyCognition & nervesEnergy & fatigue

High relevance

Lion's Mane · 2021 · Research Article · Foods (Basel, Switzerland)

Effect of Pretreatment Processes on Biogenic Amines Content and Some Bioactive Compounds in Hericium erinaceus Extract.

Hericium erinaceus is reported as a source of several nutritional contents and bioactive compounds, especially β-glucan. However, various uncontrolled processes lead to the formation of byproducts that can affect human health, including biogenic amines..

Energy & fatigue

High relevance

Shiitake · 2021 · Journal Article · Journal of the science of food and agriculture

Effects of pre‐cutting treatments and combination drying with different orders on drying characteristics and physicochemical properties of Lentinula edodes

BACKGROUND: Combination drying is recognized as an energy‐efficient method utilized for dry product processing, and proper order of combination is a critical factor determining the effectiveness of the technique..

Energy & fatigueSkin & hydration

High relevance

Oyster Mushroom · 2021 · Research Article · Frontiers in microbiology

Enhanced Biocontrol of Cucumber Fusarium Wilt by Combined Application of New Antagonistic Bacteria Bacillus amyloliquefaciens B2 and Phenolic Acid-Degrading Fungus Pleurotus ostreatus P5.

Continuous monoculture of cucumber (Cucumis sativus L.) typically leads to the frequent incidence of Fusarium wilt caused by Fusarium oxysporum f. sp.

Energy & fatigue

High relevance

Niu-Chang-Chih · 2021 · Research Article · Preventive nutrition and food science

Ergostatrien-3β-ol (EK100) from Antrodia camphorata Attenuates Oxidative Stress, Inflammation, and Liver Injury In Vitro and In Vivo.

Hepatic ischemia/reperfusion (IR) injury is a complication that occurs during liver surgery, whereby hepatic tissue is injured by oxygen deficiency during ischemia, then further damaged by a cascade of inflammatory and oxidative insults when blood is resupplied during reperfusion..

OncologyImmune supportEnergy & fatigueLiver support

High relevance

Enoki · 2021 · Journal Article · Journal of food processing and preservation

Ergothioneine accumulated in the catfish muscle by supplementation of Flammulina velutipes extract prevents lipid oxidation, improves color stability, and limits soft structure of the fillet during frozen storage

This study aimed to evaluate whether ergothioneine (ESH) accumulated in catfish muscle affected to fillet quality during frozen storage. The fish after fed by feed supplemented 0 to 15% concentrated extract (CE) from Flammulina velutipes for 30 days were filleted and stored at −18 ± 0.2°C for 90 days..

Energy & fatigue

High relevance

Enoki · 2021 · Journal Article · International journal of biological macromolecules

Flammulina velutipes polysaccharide improves C57BL/6 mice gut health through regulation of intestine microbial metabolic activity.

Flammulina velutipes polysaccharides (FVP) can improve gut health through gut microbiota and metabolism regulation. In this study, the 28-days fed experiment was used to investigate gut microbime and metabolic profiling induced by FVP..

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

High relevance

Reishi · 2021 · Research Article · Journal of Zhejiang University. Science. B

Heme oxygenase-1/carbon monoxide signaling participates in the accumulation of triterpenoids of Ganoderma lucidum.

Ganoderic triterpenoids (GTs) are the primary bioactive constituents of the Basidiomycotina fungus, Ganoderma lucidum. These compounds exhibit antitumor, anti-hyperlipidemic, and immune-modulatory pharmacological activities.

OncologyImmune supportEnergy & fatigueMetabolic health

High relevance

Cordyceps · 2021 · Research Article · PeerJ

iTRAQ-based comparative proteome analyses of different growth stages revealing the regulatory role of reactive oxygen species in the fruiting body development of Ophiocordyceps sinensis.

In this study, using an isobaric tags for relative and absolute quantitation (iTRAQ ) approach coupled with LC-MS / MS and bioinformatics, the proteomes were analyzed for the crucial three stages covering the fruiting body development of Ophiocordyceps sinensis, including sclerotium (ST), primordium (PR) and mature….

Energy & fatigue

High relevance

Oyster Mushroom · 2021 · Research Article · PeerJ

Ligninolytic activity of the Penicillium chrysogenum and Pleurotus ostreatus fungi involved in the biotransformation of synthetic multi-walled carbon nanotubes modify its toxicity.

Multi-walled carbon nanotubes (MWCNTs) are of multidisciplinary scientific interest due to their exceptional physicochemical properties and a broad range of applications. However, they are considered potentially toxic nanoparticles when they accumulate in the environment..

Energy & fatigueMetabolic health

High relevance

Oyster Mushroom · 2021 · Journal Article · Journal of fluorescence

Live Cell Imaging With Biocompatible Fluorescent Carbon Quantum Dots Derived From Edible Mushrooms Agaricus bisporus, Pleurotus ostreatus, and Suillus luteus.

In the study, fluorescent imaging of live cells was performed using fluorescent carbon quantum dots derived from edible mushrooms species; Agaricus bisporus, Pleurotus ostreatus, and Suillus luteus as a fluorophore agent..

Energy & fatigue

High relevance

Turkey Tail · 2021 · Research Article · Frontiers in bioengineering and biotechnology

Mechanism of Laccase Induction via Emodin in Trametes versicolor.

Secondary metabolites of traditional Chinese herbs can prominently stimulate the production of laccase from white rot fungi during submerged fermentation. However, the molecular mechanism through which these natural products induce the production of laccase remains unknown..

Energy & fatigue

High relevance

Oyster Mushroom · 2021 · Journal Article · International journal of medicinal mushrooms

Nutritional and Bioactive Properties of an Amazon Wild Oyster Culinary-Medicinal Mushroom, Pleurotus ostreatus (Agaricomycetes): Contributions to Functional Food and Human Health.

A wild Amazonian strain of Pleurotus ostreatus (Jacq.: Fr.) P. Kumm.

Energy & fatigue

High relevance

Turkey Tail · 2021 · Journal Article · The Science of the total environment

Pesticide bioremediation by Trametes versicolor: Application in a fixed-bed reactor, sorption contribution and bioregeneration.

Although immobilization on lignocellulosic materials has recently become a promising strategy in the fungal-based technology for micropollutant bioremediation, research evidence in this area is still scarce and significant knowledge gaps need to be addressed..

Energy & fatigueGut & microbiome

High relevance

Chaga · 2021 · Journal Article · Journal of natural medicines

Phelligridin D from Inonotus obliquus attenuates oxidative stress and accumulation of ECM in mesangial cells under high glucose via activating Nrf2.

Diabetic nephropathy (DN) is one of the most common microvascular complications of diabetes mellitus and becomes the financial burden and health problem. Pathogenesis of DN has revealed that high glucose has resulted in the oxidative stress and accumulation of extracellular matrix (ECM)..

Energy & fatigueMetabolic healthSkin & hydration

High relevance

Oyster Mushroom · 2021 · Journal Article · Journal of dietary supplements

Pleurotus ostreatus and Lentinus subnudus supplemented diets restore altered acetylcholinesterase and butyrylcholinesterase activities and improve antioxidant status in transgenic Drosophila melanogaster model.

Pleurotus ostreatus (P. ostreatus) and Lentinus subnudus (L.

Cognition & nervesEnergy & fatigue

High relevance

Niu-Chang-Chih · 2021 · Journal Article · Phytotherapy research: PTR

Protective effects of Antrodia camphorata extract against hypoxic cell injury and ischemic stroke brain damage.

Ischemic stroke is the most prevalent stroke condition in the world resulted in either a transient ischemic attack or long-lasting neurological problems due to the interrupted or reduced blood flow to the brain..

Cognition & nervesEnergy & fatigue

High relevance

Turkey Tail · 2021 · Research Article · Journal of fungi (Basel, Switzerland)

Proteomics Reveals Octyl Gallate as an Environmentally Friendly Wood Preservative Leading to Reactive Oxygen Species-Driven Metabolic Inflexibility and Growth Inhibition in White-Rot Fungi (Lenzites betulina and Trametes versicolor).

The most commonly applied wood preservatives are based on creosote, pentachlorophenol, and waterborne chromate copper arsenate, which negatively affect the environment. Thus, environmentally friendly wood preservatives are required..

Energy & fatigueMetabolic health

High relevance

Shiitake · 2021 · Research Article · International journal of molecular sciences

Selenium-Containing Exopolysaccharides Isolated from the Culture Medium of Lentinula edodes: Structure and Biological Activity.

In continuation of our research on the influence of selenium incorporation on the biosynthesis, structure, and immunomodulatory and antioxidant activities of polysaccharides of fungal origin, we have isolated from a post-culture medium of Lentinula edodes a selenium (Se)-containing exopolysaccharide fraction composed….

OncologyImmune supportEnergy & fatigue

High relevance

Oyster Mushroom · 2021 · Research Article · Journal of fungi (Basel, Switzerland)

Strain Degeneration in Pleurotus ostreatus: A Genotype Dependent Oxidative Stress Process Which Triggers Oxidative Stress, Cellular Detoxifying and Cell Wall Reshaping Genes.

Strain degeneration has been defined as a decrease or loss in the yield of important commercial traits resulting from subsequent culture, which ultimately leads to Reactive Oxygen Species (ROS) production. Pleurotus ostreatus is a lignin-producing nematophagous edible mushroom..

Energy & fatigue

High relevance

Enoki · 2021 · Journal Article · International journal of biological macromolecules

The biological regulatory activities of Flammulina velutipes polysaccharide in mice intestinal microbiota, immune repertoire and heart transcriptome.

The effects of a novel Flammulina velutipes polysaccharide (FVP) on intestinal microbiota, immune repertoire and heart transcriptome were investigated in this study. The results showed that FVP treatment could effectively regulate the abundance of colonic microbiota..

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

High relevance

Oyster Mushroom · 2021 · Research Article · Animals: an open access journal from MDPI

Treatment of Rice Stubble with Pleurotus ostreatus and Urea Improves the Growth Performance in Slow-Growing Goats.

The objective of this study was to evaluate the efficacy of the fungal treatment (Pleurotus ostreatus) of urea-treated rice stubble on growth performance in slow-growing goats..

Energy & fatigueMetabolic healthGut & microbiome

High relevance

Oyster Mushroom · 2021 · Research Article · Microbial cell factories

Trehalose alleviates high-temperature stress in Pleurotus ostreatus by affecting central carbon metabolism.

BACKGROUND: Trehalose, an intracellular protective agent reported to mediate defense against many stresses, can alleviate high-temperature-induced damage in Pleurotus ostreatus..

Energy & fatigueMetabolic health

High relevance

King Oyster · 2019 · Journal Article · Journal of food science

Production of Pork Sausages Using Pleaurotus eryngii with Different Treatments as Replacements for Pork Back Fat.

The effects of four treatments of Pleurotus eryngii (king oyster mushroom) as replacements for pork back fat were evaluated for the physicochemical, technological, and sensory properties; nitrite content; and amino acid profile in pork sausages..

Energy & fatigue

High relevance

Chaga · 2024 · Research Support, Non U.S. Gov'T · Scientific reports

Chaga mushroom extract suppresses oral cancer cell growth via inhibition of energy metabolism.

Oral cancer stands as a prevalent maligancy worldwide; however, its therapeutic potential is limited by undesired effects and complications. As a medicinal edible fungus, Chaga mushroom (Inonotus obliquus) exhibits anticancer effects across diverse cancers..

OncologyEnergy & fatigue

High relevance

Cordyceps · 2023 · Journal Article · Journal of microencapsulation

Nanoencapsulated cordyceps extract enhances collagen synthesis and skin cell regeneration through antioxidation and autophagy.

Oxidative stress from reactive oxygen species is the main cause of skin ageing. Cordycepin, a bioactive compound of Cordyceps militaris, contains antioxidant activity..

Energy & fatigueSkin & hydration

High relevance

Cordyceps · 2022 · Research Article · Ecology and evolution

Comparative analysis of the complete mitochondrial genomes of four cordyceps fungi.

Cordyceps is a large group of entomogenous, medicinally important fungi. In this study, we sequenced, assembled, and annotated the entire mitochondrial genome of Ophiocordyceps xuefengensis, in addition to comparing it against other three complete cordyceps mitogenomes that were previously published..

Energy & fatigue

High relevance

Cordyceps · 2021 · Journal Article · Journal of ethnopharmacology

Discovery of the signal pathways and major bioactive compounds responsible for the anti-hypoxia effect of Chinese cordyceps.

ETHNOPHARMACOLOGICAL RELEVANCE: Hypoxia will cause an increase in the rate of fatigue and aging. Chinese cordyceps, a parasitic Thitarodes insect-Ophiocordyceps sinensis fungus complex in the Qinghai-Tibet Plateau, has long been used to ameliorate human conditions associated with aging and senescence, it is….

Energy & fatigueSkin & hydration

High relevance

Maitake · 2021 · Research Article · Foods (Basel, Switzerland)

Prebiotic Effect of Maitake Extract on a Probiotic Consortium and Its Action after Microbial Fermentation on Colorectal Cell Lines.

Maitake (Grifola frondosa) is a medicinal mushroom known for its peculiar biological activities due to the presence of functional components, including dietary fibers and glucans, that can improve human health through the modulation of the gut microbiota..

OncologyEnergy & fatigueGut & microbiome

High relevance

Cordyceps · 2021 · Journal Article · Journal of ethnopharmacology

Toxicological safety evaluation of the cultivated Chinese cordyceps.

ETHNOPHARMACOLOGICAL RELEVANCE: The Chinese cordyceps, a parasitic Thitarodes insect-Ophiocordyceps sinensis fungus complex in the Qinghai-Tibet Plateau, is one of the most valuable traditional Chinese medicines and health food for ameliorating conditions associated with aging and for treating fatigue, night sweats,….

Energy & fatigueMetabolic healthLiver supportRespiratory

High relevance

Cordyceps · 2020 · Research Article · Animals: an open access journal from MDPI

Effect of Spent Mushroom (Cordyceps militaris) on Growth Performance, Immunity, and Intestinal Microflora in Weaning Pigs.

There are limited published reports regarding the optimal dosage of spent mushroom. This study investigated the effect of various levels of spent mushroom derived from C..

OncologyImmune supportEnergy & fatigueMetabolic health

High relevance

Cordyceps · 2018 · Journal Article · Proceedings for Annual Meeting of The Japanese Pharmacological Society

Protective effect of Echinacoside, Cistanche and Cordyceps militaris extract on reproductive damage in rats

Metadata-grounded summary: This journal article indexes research on Cordyceps militaris in Proceedings for Annual Meeting of The Japanese Pharmacological Society in 2018. MycoData maps the paper to energy & fatigue based on its title, species context, article metadata, and study classification..

Energy & fatigue

High relevance

Cordyceps · 2016 · Research Article · Experimental and therapeutic medicine

Separation of cordycepin from Cordyceps militaris fermentation supernatant using preparative HPLC and evaluation of its antibacterial activity as an NAD+-dependent DNA ligase inhibitor.

Cordycepin exhibits various bio-activities, including anticancer, antibacterial, antiviral and immune regulation activities, and is a significant focus of research. However, the preparation of high-purity cordycepin remains challenging..

OncologyImmune supportEnergy & fatigueRespiratory

High relevance

Cordyceps · 2016 · Journal Article · JOURNAL OF THE BREWING SOCIETY OF JAPAN

The Bioactive Functions by the Extract of Cordyceps Militaris Soaked in the Sweetpotato Shochu

Metadata-grounded summary: This journal article indexes research on Cordyceps militaris in JOURNAL OF THE BREWING SOCIETY OF JAPAN in 2016. MycoData maps the paper to energy & fatigue based on its title, species context, article metadata, and study classification..

Energy & fatigue

High relevance

King Oyster · 2026 · Research Article · Synthetic and systems biotechnology

Development of mycelium-reinforced dialdehyde cellulose-polyvinyl alcohol composites for emerging high-performance sustainable materials.

Dialdehyde cellulose (DAC), featuring reactive carbonyl groups introduced via oxidation of hemp-derived cellulose fibers (confirmed by FTIR spectroscopy), was synthesized to promote strong hydrogen bonding with polyvinyl alcohol (PVA) for composite development..

Energy & fatigue

High relevance

King Oyster · 2025 · Journal Article · Chemistry & biodiversity

Composition Analysis and In Vitro Investigation on Antioxidant, α-Amylase, and Pancreatic Lipase Inhibitory Activities of Major Mushrooms in Qinling Mountains.

Edible mushrooms exhibit a range of pharmacological activities, including anticancer, antimicrobial, antioxidant, anti-obesity, and hepatoprotective effects, thereby holding significant potential for applications in the development of functional foods..

OncologyImmune supportEnergy & fatigueMetabolic health

High relevance

Reishi · 2025 · Research Article · Current issues in molecular biology

Ganoderma lucidum Extract Modulates Gene Expression Profiles Associated with Antioxidant Defense, Cytoprotection, and Senescence in Human Dermal Fibroblasts: Investigation of Quantitative Gene Expression by qPCR.

Cellular senescence plays a crucial role in skin aging, with senescent dermal fibroblasts contributing to reduced skin elasticity and increased inflammation. This study investigated the potential of Ganoderma lucidum (Reishi) ethanol extract to modulate the senescent phenotype of human dermal fibroblasts..

Immune supportEnergy & fatigueSkin & hydration

High relevance

Lion's Mane · 2020 · Review · Antioxidants (Basel, Switzerland)

Potential Antidepressant Effects of Scutellaria baicalensis, Hericium erinaceus and Rhodiola rosea.

Recent studies focused on the pharmacology and feasibility of herbal compounds as a potential strategy to target a variety of human diseases ranging from metabolic to brain disorders..

Immune supportCognition & nervesEnergy & fatigueMetabolic health

High relevance

Chaga · 2019 · Review · Phytotherapy research: PTR

The pharmacological potential and possible molecular mechanisms of action of Inonotus obliquus from preclinical studies.

The use of mushrooms as functional foods and in the treatment of diseases has a long history. Inonotus obliquus is a mushroom belonging to the Hymenochaetaceae family and has possible anticancer, antiviral, and hypoglycemic properties..

OncologyImmune supportEnergy & fatigueMetabolic health