MycoData

Energy & fatigueMetabolic health

Reishi · 2025 · Research Article · Theranostics

GLSP mitigates vascular aging by promoting Sirt7-mediated Keap1 deacetylation and Keap1-Nrf2 dissociation.

Background and Purpose: Vascular aging is a prior marker of human aging and a significant contributor to atherosclerosis and vascular calcification. However, there are limited pharmacological options available to mitigate vascular aging..

Immune supportMetabolic healthGut & microbiome

Snow Fungus · 2025 · Research Article · Journal of advanced research

Glycosidic linkages of fungus polysaccharides influence the anti-inflammatory activity in mice.

INTRODUCTION: Over decades, the source-function relationships of bioactive polysaccharides have been progressively investigated, however, it is still unclear how a defined structure may conduce to the bioactivities of polysaccharides..

OncologyImmune supportEnergy & fatigueRespiratory

Oyster Mushroom · 2025 · Research Article · Biotechnology and bioengineering

Gold Nanoparticles Coated With Hydrophobin-ProteinA Fusion Protein: Development of a Versatile Immunosensing Platform.

Advancing immunosensing technologies hinges on the development of next-generation surface functionalization methods, as the precise anchoring of antibodies on transducer interface is essential for achieving high sensitivity and selectivity..

Reishi · 2025 · Journal Article · Biomimetics (Basel, Switzerland)

Growth Propagation of Liquid Spawn on Non-Woven Hemp Mats to Inform Digital Biofabrication of Mycelium-Based Composites.

Mycelium-based composites (MBCs) are highly valued for their ability to transform low-value organic materials into sustainable building materials, offering significant potential for decarbonizing the construction sector..

Cognition & nervesGut & microbiome

Reishi · 2025 · Research Article · Archives of medical science: AMS

Gut microbiota and insomnia: Mendelian randomization and network pharmacology to predict potential intervention with traditional Chinese medicine.

INTRODUCTION: The aim of the study was to identify gut microbiota (GM) with genetic causal effects on insomnia using Mendelian randomization (MR) and predict potential traditional Chinese medicines (TCMs) for GM-targeted intervention in insomnia..

Immune supportCognition & nervesMetabolic healthGut & microbiome

Oyster Mushroom · 2025 · Research Article · Frontiers in immunology

Gut mycobiota dysbiosis and systemic immune dysfunction in Chinese schizophrenia patients with metabolic syndrome.

While bacterial dysbiosis has been extensively studied in schizophrenia with metabolic syndrome (SZ-MetS), the role of gut mycobiota in this comorbidity remains unclear..

Immune supportMetabolic healthGut & microbiome

Reishi · 2025 · Journal Article · Poultry Science

Harnessing mushrooms for poultry nutrition: Boosting health, immunity, and productivity

Edible mushrooms, the fruiting bodies of fungi, are emerging as promising functional feed additives in poultry nutrition, offering a sustainable alternative to synthetic growth promoters..

Maitake · 2025 · Journal Article · International journal of medicinal mushrooms

Health Foods Made from Medicinal Mushrooms: Innovative Recipes Created by an Italian Chef.

An innovative menu based on the use of fresh and dried medicinal mushrooms, which is energetic, healthy, easy to make, and adaptable to any type of diet, is presented..

Reishi · 2025 · Research Article · Nature communications

High-content screening identifies ganoderic acid A as a senotherapeutic to prevent cellular senescence and extend healthspan in preclinical models.

Accumulated senescent cells during the aging process are a key driver of functional decline and age-related disorders. Here, we identify ganoderic acid A (GAA) as a potent anti-senescent compound with low toxicity and favorable drug properties through high-content screening..

Metabolic health

Oyster Mushroom · 2025 · Research Article · Frontiers in plant science

High-quality carrots in relation to the superior phloem parenchyma cells and proportion of xylem vessel in coordinated water-fertilizer management.

BACKGROUND: The coordinated management of water and fertilizer is essential for improving vegetable yield and quality. However, its role in connecting quality with the anatomical structure of the phloem and xylem in carrots remains unclear..

Energy & fatigueMetabolic health

Shiitake · 2025 · Journal Article · International journal of medicinal mushrooms

Identification and Quantification of α-D-Glucopyranosyl-Isomaltol, α-D-Maltosyl-Isomaltol, and α-Glucan in AHCCŴ Cultured Mushroom Mycelia Extract.

Consumer demand and use of mushrooms and their extracts for health promotion is increasing in the United States and worldwide. In order to further advance the science and quality assurance of mushroom products and ingredients, analytical data is needed to identify and standardize biochemical markers..

Oyster Mushroom · 2025 · Journal Article · Food chemistry

Identification of new selenium compounds produced by edible mushrooms.

The ability of two common edible mushroom species, Pleurotus ostreatus and Hericium coralloides, to metabolize selenium when grown in the presence of selenite (Se(IV)) and selenate (Se(VI)) was investigated. The efficiency of selenium absorption was 4-8 times higher when Se(IV) was used as selenium source..

Shiitake · 2025 · Journal Article · International Journal of Gastronomy and Food Science

Improvement in texture and flavor of prepared meat patties with natural marination ingredients

This study investigated the effects of four natural ingredients including Lentinula edodes (L. edodes) powder, yeast extract, germinated brown rice (GBR) powder, and chicken soup on the texture and flavor of prepared meat patties..

Mesima · 2025 · Journal Article · International journal of medicinal mushrooms

In Silico Interaction of Phellilane L with HmuY: A Promising Therapeutic Strategy against Porphyromonas gingivalis in Chronic Periodontitis.

This study investigates the in silico interaction between Phellilane L, a sesquiterpene metabolite from Phellinus linteus, and the Porphiromonas gingivalis HmuY protein, a key player in chronic periodontitis pathogenesis..

Cognition & nervesEnergy & fatigue

Reishi · 2025 · Journal Article · International journal of medicinal mushrooms

In Silico Investigation of Ganoderic Acid A Targeting Amyloid-Beta and Tau Protein Aggregation in Alzheimer's Disease.

Alzheimer's disease (AD) represents a significant challenge in neurodegenerative disorders, characterized by the accumulation of amyloid-beta (Aβ) plaques and tau protein tangles in the brain. Current treatments provide symptomatic relief but do not halt disease progression..

Turkey Tail · 2025 · Journal Article · Composites Part A

In situ growth of mycelium in a lignocellulosic scaffold enabled by cellulose nanofibrils for lightweight insulation

Mycelium-lignocellulosic fiber composites (MLFCs) offer a promising sustainable alternative to lightweight, petroleum-based materials and are gaining significant interest across various sectors..

Energy & fatigueGut & microbiome

Oyster Mushroom · 2025 · Research Article · Veterinary world

In vitro evaluation of ammoniation-fungal fermentation of citronella straw: Impacts on digestibility, ruminal fermentation, and palatability in Indonesian native sheep.

BACKGROUND AND AIM: Citronella straw (Cymbopogon nardus L.), a byproduct of essential oil extraction, is rich in lignin therefore poorly digestible, which limits its use as livestock feed..

Oyster Mushroom · 2025 · Journal Article · The Science of the total environment

Inclusion of biochar in mushroom substrate influences microbial community composition of the substrate and elemental composition of the fruiting bodies.

Due to its structure, biochar makes the soil porous and oxygen-rich, enhancing the water-holding capacity and increasing the cation exchange capacity for a longer duration. These aspects could also be favourable for mushroom production.

Turkey Tail · 2025 · Journal Article · Journal of Ethnopharmacology

Inhibition of Pseudomonas aeruginosa Quorum Sensing-Regulated Behaviors by Mushroom Extracts

Microbial biofilm formation, a quorum sensing (QS) phenomenon based on cell-to-cell communication through ligand-receptor interactions, is one of the major causes of nosocomial and chronic infections, foodborne diseases and associated deaths..

Turkey Tail · 2025 · Journal Article · Journal of ethnopharmacology

Inhibition of Pseudomonas aeruginosa quorum sensing-regulated behaviors by mushroom extracts.

ETHNOPHARMACOLOGICAL RELEVANCE: Microbial biofilm formation, a quorum sensing (QS) phenomenon based on cell-to-cell communication through ligand-receptor interactions, is one of the major causes of nosocomial and chronic infections, foodborne diseases and associated deaths..

OncologyImmune supportEnergy & fatigueMetabolic health

Zhu Ling · 2025 · Journal Article · Journal of ethnopharmacology

Injinoryeong-San attenuates metabolic dysfunction-associated steatohepatitis via regulation of YAP/TAZ-signaling pathway.

ETHNOPHARMACOLOGICAL RELEVANCE: Injinoryeong-san (IJO), known as Yinchen-Wuling Powder in Chinese medicine, is a traditional herbal formula comprising six herbal medicinal plants, including Atractylodes macrocephala Koidz., Polyporus umbellatus (Pers.) Fries, Poria cocos (Schw.) Wolf, Cinnamomum cassia Presl, Alisma….

Turkey Tail · 2025 · Research Article · Biotechnology for biofuels and bioproducts

Insight into the role of antioxidant in microbial lignin degradation: Ascorbic acid as a fortifier of lignin-degrading enzymes.

BACKGROUND: Microbial-driven lignin depolymerization has emerged as a promising approach for lignin degradation. However, this process is hindered by the limited activity of lignin-degrading enzymes.

Chaga · 2025 · Research Article · Journal of microbiology and biotechnology

Integrated Assessment of Growth and Protein Content in Basidiomycetous Fungi for Mycoprotein Production.

The rising demand for sustainable and health-conscious protein sources has driven interest in fungal-derived mycoprotein as an alternative to conventional meat products..

Reishi · 2025 · Journal Article · International journal of medicinal mushrooms

Integrated Process for Mycoprotein and Enzyme Production during Solid-State Fermentation of Lignocellulosic Materials Using Medicinal Mushrooms.

This study evaluated the potential of Ganoderma lucidum BCC447 and Pleurotus ostreatus BCC2191 to enrich plant materials with mycoproteins and cellulases through solid-state fermentation (SSF) of wheat bran, shredded wheat, and soybean meal for the use of the fermented product as a natural food additive in poultry and….

Turkey Tail · 2025 · Research Article · Materials (Basel, Switzerland)

Investigating the Efficacy of Established Chemical Wood Modifications on Large-Diameter Pine: Durability Against Basidiomycetes.

In Germany, Pinus sylvestris is a dominant tree species, and many trees with large diameters are not utilised due to difficulties with processing. However, older pines have larger volumes of sapwood, and boards with a high sapwood content can be produced.

Snow Fungus · 2025 · Research Article · China CDC weekly

Isolation and Identification of Burkholderia gladioli pathovar cocovenenans from Black Fungus and Characteristics of the Bon Gene Cluster - Shanghai Municipality, China, 2023.

WHAT IS ALREADY KNOWN ABOUT THIS TOPIC?: Burkholderia gladioli (B. gladioli) pathovar cocovenenans (BGC), a foodborne pathogen, can cause lethal poisoning.

Turkey Tail · 2025 · Research Article · Brazilian journal of microbiology: [publication of the Brazilian Society for Microbiology]

Kraft lignin biobleaching by a dye-decolorizing peroxidase from the Antarctic Pseudomonas sp. AU10 strain.

Pseudomonas sp. AU10 is an Antarctic psychrotolerant bacterium that produces a dye-decolorizing peroxidase (DyP-AU10).

OncologyImmune supportGut & microbiome

Almond Mushroom · 2025 · Research Article · Digestive diseases and sciences

LeLISA: A New Lectin-Based Immunoassay for Evaluation of Mucinous and Serous Content in Pancreatic Cystic Neoplasms.

BACKGROUND: The discrimination of mucinous from serous pancreatic cysts and pseudocysts is an important clinical issue. We aimed to investigate the possibility of using our LeLISA test for distinguishing between different types of pancreatic cysts..

OncologyImmune supportEnergy & fatigue

Shiitake · 2025 · Journal Article · International Journal of Biological Macromolecules

Lentinan attenuates histone deacetylation of SOCS1 promoter to remodel autophagy via JAK2/STAT3 pathway for the prevention of intervertebral disc degeneration

Intervertebral disc degeneration (IVDD), driven by nucleus pulposus cell (NPCs) apoptosis, extracellular matrix (ECM) dyshomeostasis, and inflammation, lacks effective therapies. Lentinan (LNT), a polysaccharide from lentinula edodes, has anti-inflammatory and antioxidant properties..

OncologyImmune supportEnergy & fatigue

Shiitake · 2025 · Journal Article · International journal of biological macromolecules

Lentinan attenuates histone deacetylation of SOCS1 promoter to remodel autophagy via JAK2/STAT3 pathway for the prevention of intervertebral disc degeneration.

OncologyImmune supportCognition & nervesGut & microbiome

Shiitake · 2025 · Research Article · Frontiers in immunology

Lentinan enhances CAR-T cell potency in solid tumors by optimizing T cell differentiation.

CAR-T cell therapy has demonstrated remarkable success in treating hematologic malignancies; however, its efficacy in solid tumors remains constrained. In this study, we demonstrate that Lentinan (LTN), an active polysaccharide derived from Lentinula edodes, potently enhances CAR-T cell function against solid tumors..

Cognition & nervesMetabolic health

Maitake · 2025 · Journal Article · Methods in molecular biology (Clifton, N.J.)

Maistero-2, a Novel Probe for Sterols: Application for Visualizing Cellular Cholesterol.

Maistero-2 is a novel, non-toxic cholesterol-binding protein derived from an edible mushroom Grifola frondosa mRNA. Maistero-2 specifically binds to lipid membranes containing 3-hydroxy sterols with a lower cholesterol concentration threshold than cholesterol-binding domain 4 (D4) of perfringolysin O (PFO) and….

Reishi · 2025 · Journal Article · Biotechnology and bioengineering

Manganese Peroxidase Participates in the Liquid-Solid-Gas Triphase Regulation on Microbial Degradation of Lignocellulose in Solid-State Fermentation.

The three-phase structure of solid-state fermentation (SSF) directly affects substrate degradation and fermentation efficiency. However, the mechanism of three-phase regulation on lignocellulose utilization and microbial metabolism is still unclear..

Turkey Tail · 2025 · Journal Article · Journal of hazardous materials

Metabolic pathways for biotransformation of benzalkonium compounds in fungal- and bacteria-based biofilm reactors

Benzalkonium compounds (BACs) are quaternary ammonium biocides widely used in healthcare and industrial animal production, resulting in high concentrations in manure and wastewater..

Metabolic health

Turkey Tail · 2025 · Journal Article · Journal of hazardous materials

Metabolic pathways for biotransformation of benzalkonium compounds in fungal- and bacteria-based biofilm reactors.

Benzalkonium compounds (BACs) are quaternary ammonium biocides widely used in healthcare and industrial animal production, resulting in high concentrations in manure and wastewater..

Metabolic health

Immune supportMetabolic health

Turkey Tail · 2025 · Research Article · Communications biology

Metabolic profiling of two white-rot fungi during 4-hydroxybenzoate conversion reveals biotechnologically relevant biosynthetic pathways.

White-rot fungi are efficient organisms for the mineralization of lignin and polysaccharides into CO2 and H2O. Despite their biotechnological potential, WRF metabolism remains underexplored..

Metabolic healthGut & microbiome

Snow Fungus · 2025 · Journal Article · Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire

Metagenomics and untargeted metabolomics analyses to unravel the formation mechanism of characteristic metabolites in mung bean sour liquid during different fermentation stages

Mung Bean Sour Liquid (MBSL), a traditional fermented food indigenous to Luoyang, China, acquires its distinctive organic properties and bioactivity through complex microbial metabolic interactions..

Turkey Tail · 2025 · Research Article · Plants (Basel, Switzerland)

Microfluidic Array Enables Rapid Testing of Natural Compounds Against Xylella fastidiosa.

The bacterial pathogen Xylella fastidiosa (Xf), which causes several plant diseases with significant economic impacts on agriculture and the environment, remains a challenge to manage due to its wide host range..

Liver support

Metabolic healthGut & microbiomeSkin & hydration

Oyster Mushroom · 2025 · Research Article · Current research in food science

Modified Okara improves Noodle Properties: Effects on digestibility, structure, and functionality.

This study developed a modified okara (the product of co-fermentation with Pleurotus ostreatus and Saccharomyces cerevisiae followed by cellulase treatment), evaluating its effects on noodle quality..

Shiitake · 2025 · Research Article · Journal of nematology

Morphological and Molecular Characterization of a Novel Fungal-feeding Stem Nematode Ditylenchoides agaricivorus n. sp. (Tylenchida: Anguinidae) from Intercepted Samples.

A new species of the genus Ditylenchoides, D. agaricivorus n.

Shiitake · 2025 · Research Article · Scientific reports

Mushroom stem-based diets elicit region-specific shifts in rainbow trout gut microbiota.

The intestinal microbiota of fish plays a crucial role in host condition and health, exhibiting region-specific functions influenced by dietary components. This study evaluated the effects of mushroom stem meals from Agaricus bisporus (AB), Lentinula edodes (LE), and Pleurotus ostreatus (PO), used as sustainable….

Gut & microbiome

Reishi · 2025 · Journal Article · Bioresource Technology Reports

Mycelium biocomposites from agricultural and paper waste: Sustainable alternative to plastic foam based secondary packaging

Plastic foams like Expanded polystyrene (EPS) and Expanded Polyethylene (EPE), though common in packaging, are environmentally harmful due to their non-biodegradable nature—especially in regions with poor waste management..

Agarikon · 2025 · Journal Article · ACS applied bio materials

Natural Flavonoid and Fungal Polysaccharide-Based Redox-Responsive Nanogels for Synergistic Tumor Chemo-Immunotherapy.

Cancer remains a leading cause of global mortality, underscoring the urgent need for safe, effective, and innovative therapeutic strategies. Nanotechnology, particularly nanogels, offers promising opportunities for cancer treatment..

OncologyImmune support

Immune supportEnergy & fatigueGut & microbiomeSkin & hydration

Snow Fungus · 2025 · Journal Article · Food Research International

Natural polysaccharides mediated “low-molecular-bridging" network in fermented soybean protein gels: Interaction, microstructure, and rheological properties

This study investigated the interactions, microstructure, and rheological properties of Lactobacillus plantarum JYLP-326-fermented protein gels formed by soybean protein isolate (SPI) and three natural polysaccharides: fucoidan (FU), tremella fuciformis polysaccharide (TFP), and lycium barbarum polysaccharide (LBP)..

Immune supportEnergy & fatigueGut & microbiomeSkin & hydration

Snow Fungus · 2025 · Journal Article · Food research international (Ottawa, Ont.)

Natural polysaccharides mediated "low-molecular-bridging" network in fermented soybean protein gels: Interaction, microstructure, and rheological properties.

OncologyImmune supportEnergy & fatigueMetabolic health

Snow Fungus · 2025 · Research Article · Foods (Basel, Switzerland)

Natural Tremella Polysaccharide Mitigates DEHP-Induced Oxidative Stress and Apoptosis via Dual Regulation of Survival and Antioxidant Pathways.

Diethylhexyl phthalate (DEHP), a common environmental plasticizer, induces oxidative damage and cell apoptosis without efficient treatment. Tremella fuciformis polysaccharides (TFPs) are known natural antioxidants, yet their protection against DEHP toxicity remains unclear..

Turkey Tail · 2025 · Journal Article · Bioelectrochemistry (Amsterdam, Netherlands)

Nernst-Michaelis-Menten framework unlocks electrochemical kinetics for laccases.

Determining oxidoreductase kinetic parameters remains challenging due to spectrophotometric method limitations. Here, we present an innovative approach combining electrochemistry and enzymology principles through a novel Nernst-Michaelis-Menten theoretical framework..

OncologyImmune supportCognition & nerves

Reishi · 2025 · Research Article · International journal of molecular sciences

Network Pharmacology and Bioinformatics Study of Six Medicinal Food Homologous Plants Against Colorectal Cancer.

Integrating network pharmacological analysis and bioinformatic techniques, this study systematically investigated the molecular mechanisms of six medicinal food homologous plants (Astragalus membranaceus, Ganoderma lucidum, Dioscorea opposite, Curcuma longa, Glycyrrhiza uralensis, and Pueraria lobata) against….